Jonathan Richard, Ph.D. - Publications

Affiliations: 
2013 Microbiology and Immunology Université de Montréal, Montréal, Canada 
Area:
Virology Biology, Immunology, Microbiology Biology

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Doyon-Laliberté K, Aranguren M, Chagnon-Choquet J, Batraville LA, Dagher O, Richard J, Paniconi M, Routy JP, Tremblay C, Quintal MC, Brassard N, Kaufmann DE, Finzi A, Poudrier J, Roger M. Excess BAFF May Impact HIV-1-Specific Antibodies and May Promote Polyclonal Responses Including Those from First-Line Marginal Zone B-Cell Populations. Current Issues in Molecular Biology. 46: 25-43. PMID 38275663 DOI: 10.3390/cimb46010003  0.452
2023 Benlarbi M, Richard J, Bourassa C, Tolbert WD, Chartrand-Lefebvre C, Gendron-Lepage G, Sylla M, El-Far M, Messier-Peet M, Guertin C, Turcotte I, Fromentin R, Verly MM, Prévost J, Clark A, et al. Plasmatic HIV-1 soluble gp120 is associated with correlates of immune dysfunction and inflammation in ART-treated individuals with undetectable viremia. The Journal of Infectious Diseases. PMID 38035854 DOI: 10.1093/infdis/jiad503  0.435
2023 Benlarbi M, Richard J, Bourassa C, Tolbert WD, Chartrand-Lefebvre C, Gendron-Lepage G, Sylla M, El-Far M, Messier-Peet M, Guertin C, Turcotte I, Fromentin R, Verly MM, Prévost J, Clark A, et al. Plasmatic HIV-1 soluble gp120 is associated with immune dysfunction and inflammation in ART-treated individuals with undetectable viremia. Medrxiv : the Preprint Server For Health Sciences. PMID 37645879 DOI: 10.1101/2023.08.15.23294128  0.435
2023 Marchitto L, Benlarbi M, Prévost J, Laumaea A, Descôteaux-Dinelle J, Medjahed H, Bourassa C, Gendron-Lepage G, Kirchhoff F, Sauter D, Hahn BH, Finzi A, Richard J. Impact of HIV-1 Vpu-mediated downregulation of CD48 on NK-cell-mediated antibody-dependent cellular cytotoxicity. Mbio. e0078923. PMID 37404017 DOI: 10.1128/mbio.00789-23  0.552
2023 Boutin M, Medjahed H, Nayrac M, Lotke R, Gendron-Lepage G, Bourassa C, Sauter D, Richard J, Finzi A. Temsavir Modulates HIV-1 Envelope Conformation by Decreasing Its Proteolytic Cleavage. Viruses. 15. PMID 37243275 DOI: 10.3390/v15051189  0.472
2023 Ding S, Tolbert WD, Zhu H, Lee D, Marchitto L, Higgins T, Zhao X, Nguyen D, Sherburn R, Richard J, Gendron-Lepage G, Medjahed H, Mohammadi M, Abrams C, Pazgier M, et al. Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC. Viruses. 15. PMID 37243271 DOI: 10.3390/v15051185  0.537
2023 Ding S, Tolbert WD, Zhu H, Lee D, Higgins T, Zhao X, Nguyen D, Sherburn R, Richard J, Lepage GG, Medjahed H, Mohammadi M, Abrams C, Pazgier M, Smith AB, et al. Piperidine CD4-mimetic compounds expose vulnerable Env epitopes sensitizing HIV-1-infected cells to ADCC. Biorxiv : the Preprint Server For Biology. PMID 36993184 DOI: 10.1101/2023.03.23.533923  0.537
2023 Fritschi CJ, Anang S, Gong Z, Mohammadi M, Richard J, Bourassa C, Severino KT, Richter H, Yang D, Chen HC, Chiu TJ, Seaman MS, Madani N, Abrams C, Finzi A, et al. Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2222073120. PMID 36961924 DOI: 10.1073/pnas.2222073120  0.527
2023 Richard J, Prévost J, Bourassa C, Brassard N, Boutin M, Benlarbi M, Goyette G, Medjahed H, Gendron-Lepage G, Gaudette F, Chen HC, Tolbert WD, Smith AB, Pazgier M, Dubé M, et al. Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120. Cell Chemical Biology. PMID 36958337 DOI: 10.1016/j.chembiol.2023.03.003  0.684
2023 Laumaea A, Marchitto L, Ding S, Beaudoin-Bussières G, Prévost J, Gasser R, Chatterjee D, Gendron-Lepage G, Medjahed H, Chen HC, Smith AB, Ding H, Kappes JC, Hahn BH, Kirchhoff F, ... Richard J, et al. Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity. Cell Reports. 42: 111983. PMID 36640355 DOI: 10.1016/j.celrep.2022.111983  0.418
2022 Chaplain C, Fritschi CJ, Anang S, Gong Z, Richard J, Bourassa C, Liang S, Mohammadi M, Park J, Finzi A, Madani N, Sodroski JG, Abrams CF, Hendrickson WA, Smith AB. Structural and Functional Characterization of Indane-Core CD4-Mimetic Compounds Substituted with Heterocyclic Amines. Acs Medicinal Chemistry Letters. 14: 51-58. PMID 36655122 DOI: 10.1021/acsmedchemlett.2c00376  0.32
2022 Matsumoto K, Kuwata T, Tolbert WD, Richard J, Ding S, Prévost J, Takahama S, Judicate GP, Ueno T, Nakata H, Kobayakawa T, Tsuji K, Tamamura H, Smith AB, Pazgier M, et al. Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates. Journal of Virology. e0163822. PMID 36511698 DOI: 10.1128/jvi.01638-22  0.363
2022 Prévost J, Anand SP, Rajashekar JK, Zhu L, Richard J, Goyette G, Medjahed H, Gendron-Lepage G, Chen HC, Chen Y, Horwitz JA, Grunst MW, Zolla-Pazner S, Haynes BF, Burton DR, et al. HIV-1 Vpu restricts Fc-mediated effector functions in vivo. Cell Reports. 41: 111624. PMID 36351384 DOI: 10.1016/j.celrep.2022.111624  0.512
2022 Anang S, Richard J, Bourassa C, Goyette G, Chiu TJ, Chen HC, Smith AB, Madani N, Finzi A, Sodroski J. Characterization of Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Variants Selected for Resistance to a CD4-Mimetic Compound. Journal of Virology. e0063622. PMID 35980207 DOI: 10.1128/jvi.00636-22  0.449
2022 Macedo AB, Levinger C, Nguyen BN, Richard J, Gupta M, Cruz CRY, Finzi A, Chiappinelli KB, Crandall KA, Bosque A. The HIV Latency Reversal Agent HODHBt Enhances NK Cell Effector and Memory-Like Functions by Increasing Interleukin-15-Mediated STAT Activation. Journal of Virology. e0037222. PMID 35867565 DOI: 10.1128/jvi.00372-22  0.396
2022 Beaudoin-Bussières G, Arduini A, Bourassa C, Medjahed H, Gendron-Lepage G, Richard J, Pan Q, Wang Z, Liang C, Finzi A. SARS-CoV-2 Accessory Protein ORF8 Decreases Antibody-Dependent Cellular Cytotoxicity. Viruses. 14. PMID 35746708 DOI: 10.3390/v14061237  0.341
2022 Nayrac M, Dubé M, Sannier G, Nicolas A, Marchitto L, Tastet O, Tauzin A, Brassard N, Lima-Barbosa R, Beaudoin-Bussières G, Vézina D, Gong SY, Benlarbi M, Gasser R, Laumaea A, ... ... Richard J, et al. Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen. Cell Reports. 39: 111013. PMID 35732172 DOI: 10.1016/j.celrep.2022.111013  0.598
2022 Nault L, Marchitto L, Goyette G, Tremblay-Sher D, Fortin C, Martel-Laferrière V, Trottier B, Richard J, Durand M, Kaufmann D, Finzi A, Tremblay C. Covid-19 vaccine immunogenicity in people living with HIV-1. Vaccine. 40: 3633-3637. PMID 35568588 DOI: 10.1016/j.vaccine.2022.04.090  0.3
2022 Boutin M, Vézina D, Ding S, Prévost J, Laumaea A, Marchitto L, Anand SP, Medjahed H, Gendron-Lepage G, Bourassa C, Goyette G, Clark A, Richard J, Finzi A. Temsavir Treatment of HIV-1-Infected Cells Decreases Envelope Glycoprotein Recognition by Broadly Neutralizing Antibodies. Mbio. e0057722. PMID 35475646 DOI: 10.1128/mbio.00577-22  0.514
2022 Robinson CA, Lyddon TD, Gil HM, Evans DT, Kuzmichev YV, Richard J, Finzi A, Welbourn S, Rasmussen L, Nebane NM, Gupta VV, Ananthan S, Cai Z, Wonderlich ER, Augelli-Szafran CE, et al. Novel Compound Inhibitors of HIV-1 Vpu. Viruses. 14. PMID 35458546 DOI: 10.3390/v14040817  0.356
2022 Prévost J, Richard J, Gasser R, Medjahed H, Kirchhoff F, Hahn BH, Kappes JC, Ochsenbauer C, Duerr R, Finzi A. Detection of the HIV-1 accessory proteins Nef and Vpu by flow cytometry represents a new tool to study their functional interplay within a single infected CD4+ T cell. Journal of Virology. jvi0192921. PMID 35080425 DOI: 10.1128/jvi.01929-21  0.538
2021 Nayrac M, Dubé M, Sannier G, Nicolas A, Marchitto L, Tastet O, Tauzin A, Brassard N, Beaudoin-Bussières G, Vézina D, Gong SY, Benlarbi M, Gasser R, Laumaea A, Bourassa C, ... ... Richard J, et al. Temporal associations of B and T cell immunity with robust vaccine responsiveness in a 16-week interval BNT162b2 regimen. Biorxiv : the Preprint Server For Biology. PMID 34981046 DOI: 10.1101/2021.12.18.473317  0.597
2021 Tauzin A, Gong SY, Beaudoin-Bussières G, Vézina D, Gasser R, Nault L, Marchitto L, Benlarbi M, Chatterjee D, Nayrac M, Laumaea A, Prévost J, Boutin M, Sannier G, Nicolas A, ... ... Richard J, et al. Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses. Cell Host & Microbe. PMID 34953513 DOI: 10.1016/j.chom.2021.12.004  0.534
2021 Brunet-Ratnasingham E, Anand SP, Gantner P, Dyachenko A, Moquin-Beaudry G, Brassard N, Beaudoin-Bussières G, Pagliuzza A, Gasser R, Benlarbi M, Point F, Prévost J, Laumaea A, Niessl J, Nayrac M, ... ... Richard J, et al. Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality. Science Advances. 7: eabj5629. PMID 34826237 DOI: 10.1126/sciadv.abj5629  0.471
2021 Anand SP, Prévost J, Descôteaux-Dinelle J, Richard J, Nguyen DN, Medjahed H, Chen HC, Smith AB, Pazgier M, Finzi A. HIV-1 Envelope Glycoprotein Cell Surface Localization Is Associated with Antibody-Induced Internalization. Viruses. 13. PMID 34696383 DOI: 10.3390/v13101953  0.398
2021 Richard J, Nguyen DN, Tolbert WD, Gasser R, Ding S, Vézina D, Yu Gong S, Prévost J, Gendron-Lepage G, Medjahed H, Gottumukkala S, Finzi A, Pazgier M. Across Functional Boundaries: Making Nonneutralizing Antibodies To Neutralize HIV-1 and Mediate Fc-Mediated Effector Killing of Infected Cells. Mbio. e0140521. PMID 34579568 DOI: 10.1128/mBio.01405-21  0.502
2021 Anand SP, Ding S, Tolbert WD, Prévost J, Richard J, Gil HM, Gendron-Lepage G, Cheung WF, Wang H, Pastora R, Saxena H, Wakarchuk W, Medjahed H, Wines BD, Hogarth PM, et al. Enhanced ability of plant-derived PGT121 glycovariants to eliminate HIV-1-infected cells. Journal of Virology. JVI0079621. PMID 34232070 DOI: 10.1128/JVI.00796-21  0.506
2021 Rajashekar JK, Richard J, Beloor J, Prévost J, Anand SP, Beaudoin-Bussières G, Shan L, Herndler-Brandstetter D, Gendron-Lepage G, Medjahed H, Bourassa C, Gaudette F, Ullah I, Symmes K, Peric A, et al. Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir. Cell Host & Microbe. PMID 34019804 DOI: 10.1016/j.chom.2021.04.014  0.55
2020 Vézina D, Gong SY, Tolbert WD, Ding S, Nguyen D, Richard J, Gendron-Lepage G, Melillo B, Smith AB, Pazgier M, Finzi A. Stabilizing the HIV-1 envelope glycoprotein State 2A conformation. Journal of Virology. PMID 33298541 DOI: 10.1128/JVI.01620-20  0.305
2020 Planas D, Fert A, Zhang Y, Goulet JP, Richard J, Finzi A, Ruiz MJ, Marchand LR, Chatterjee D, Chen H, Salinas TRW, Gosselin A, Cohen EA, Routy JP, Chomont N, et al. Pharmacological Inhibition of PPARy Boosts HIV Reactivation and Th17 Effector Functions, While Preventing Progeny Virion Release and de Infection. Pathogens & Immunity. 5: 177-239. PMID 33089034 DOI: 10.20411/pai.v5i1.348  0.638
2020 Hopfensperger K, Richard J, Stürzel CM, Bibollet-Ruche F, Apps R, Leoz M, Plantier JC, Hahn BH, Finzi A, Kirchhoff F, Sauter D. Convergent Evolution of HLA-C Downmodulation in HIV-1 and HIV-2. Mbio. 11. PMID 32665270 DOI: 10.1128/Mbio.00782-20  0.568
2020 Niessl J, Baxter AE, Morou A, Brunet-Ratnasingham E, Sannier G, Gendron-Lepage G, Richard J, Delgado GG, Brassard N, Turcotte I, Fromentin R, Bernard NF, Chomont N, Routy JP, Dubé M, et al. Persistent expansion and Th1-like skewing of HIV-specific circulating T follicular helper cells during antiretroviral therapy. Ebiomedicine. 54: 102727. PMID 32268275 DOI: 10.1016/J.Ebiom.2020.102727  0.729
2020 Prévost J, Edgar CR, Richard J, Trothen SM, Jacob RA, Mumby MJ, Pickering S, Dubé M, Kaufmann DE, Kirchhoff F, Neil SJD, Finzi A, Dikeakos JD. HIV-1 Vpu downregulates Tim-3 from the surface of infected CD4 T cells. Journal of Virology. PMID 31941771 DOI: 10.1128/Jvi.01999-19  0.747
2019 Ding S, Grenier MC, Tolbert WD, Vézina D, Sherburn R, Richard J, Prévost J, Chapleau JP, Gendron-Lepage G, Medjahed H, Abrams C, Sodroski J, Pazgier M, Smith AB, Finzi A. A new family of small-molecule CD4-mimetic compounds contact the highly conserved aspartic acid 368 of HIV-1 gp120 and mediates ADCC. Journal of Virology. PMID 31554684 DOI: 10.1128/Jvi.01325-19  0.474
2019 Prévost J, Pickering S, Mumby MJ, Medjahed H, Gendron-Lepage G, Delgado GG, Dirk BS, Dikeakos JD, Stürzel CM, Sauter D, Kirchhoff F, Bibollet-Ruche F, Hahn BH, Dubé M, Kaufmann DE, ... ... Richard J, et al. Upregulation of BST-2 by Type I Interferons Reduces the Capacity of Vpu To Protect HIV-1-Infected Cells from NK Cell Responses. Mbio. 10. PMID 31213558 DOI: 10.1128/Mbio.01113-19  0.721
2019 Alsahafi N, Bakouche N, Kazemi M, Richard J, Ding S, Bhattacharyya S, Das D, Anand SP, Prévost J, Tolbert WD, Lu H, Medjahed H, Gendron-Lepage G, Ortega Delgado GG, Kirk S, et al. An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity. Cell Host & Microbe. 25: 578-587.e5. PMID 30974085 DOI: 10.1016/J.Chom.2019.03.002  0.529
2019 Anand SP, Grover JR, Tolbert WD, Prévost J, Richard J, Ding S, Baril S, Medjahed H, Evans DT, Pazgier M, Mothes W, Finzi A. Antibody-induced internalization of HIV-1 Env proteins limits the surface expression of the closed conformation of Env. Journal of Virology. PMID 30894474 DOI: 10.1128/Jvi.00293-19  0.56
2019 Lee WS, Prévost J, Richard J, van der Sluis RM, Lewin SR, Pazgier M, Finzi A, Parsons MS, Kent SJ. CD4- and time-dependent susceptibility of HIV-1-infected cells to ADCC. Journal of Virology. PMID 30842324 DOI: 10.1128/Jvi.01901-18  0.627
2018 Anand SP, Prévost J, Baril S, Richard J, Medjahed H, Chapleau JP, Tolbert WD, Kirk S, Smith AB, Wines BD, Kent SJ, Hogarth PM, Parsons MS, Pazgier M, Finzi A. Two families of Env antibodies efficiently engage Fc-gamma receptors and eliminate HIV-1-infected cells. Journal of Virology. PMID 30429344 DOI: 10.1128/Jvi.01823-18  0.435
2018 Alsahafi N, Anand SP, Castillo-Menendez L, Verly MM, Medjahed H, Prévost J, Herschhorn A, Richard J, Schön A, Melillo B, Freire E, Smith AB, Sodroski J, Finzi A. SOSIP changes affect human immunodeficiency virus (HIV-1) envelope glycoprotein conformation and CD4 engagement. Journal of Virology. PMID 30021898 DOI: 10.1128/Jvi.01080-18  0.397
2018 Porichis F, Hart MG, Massa A, Everett HL, Morou A, Richard J, Brassard N, Veillette M, Hassan M, Ly NL, Routy JP, Freeman GJ, Dubé M, Finzi A, Kaufmann DE. Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 29934472 DOI: 10.4049/Jimmunol.1701551  0.735
2018 Madani N, Princiotto AM, Mach L, Ding S, Prevost J, Richard J, Hora B, Sutherland L, Zhao CA, Conn BP, Bradley T, Moody MA, Melillo B, Finzi A, Haynes BF, et al. A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge. Nature Communications. 9: 2363. PMID 29915222 DOI: 10.1038/S41467-018-04758-9  0.541
2018 Prévost J, Richard J, Medjahed H, Alexander A, Jones J, Kappes JC, Ochsenbauer C, Finzi A. Incomplete downregulation of CD4 expression affects HIV-1 Env conformation and ADCC responses. Journal of Virology. PMID 29669829 DOI: 10.1128/Jvi.00484-18  0.566
2018 Richard J, Prévost J, Baxter AE, von Bredow B, Ding S, Medjahed H, Delgado GG, Brassard N, Stürzel CM, Kirchhoff F, Hahn BH, Parsons MS, Kaufmann DE, Evans DT, Finzi A. Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses. Mbio. 9. PMID 29559570 DOI: 10.1128/Mbio.00358-18  0.611
2017 Prévost J, Richard J, Ding S, Pacheco B, Charlebois R, Hahn BH, Kaufmann DE, Finzi A. Envelope glycoproteins sampling states 2/3 are susceptible to ADCC by sera from HIV-1-infected individuals. Virology. 515: 38-45. PMID 29248757 DOI: 10.1016/J.Virol.2017.12.002  0.561
2017 Richard J, Prévost J, Alsahafi N, Ding S, Finzi A. Impact of HIV-1 Envelope Conformation on ADCC Responses. Trends in Microbiology. PMID 29162391 DOI: 10.1016/J.Tim.2017.10.007  0.587
2017 Richard J, Ding S, Finzi A. Unlocking HIV-1 Env: implications for antibody attack. Aids Research and Therapy. 14: 42. PMID 28893275 DOI: 10.1186/S12981-017-0168-5  0.619
2017 Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Massanella M, Brassard N, Alsahafi N, Routy JP, Finzi A, Chomont N, Kaufmann DE. Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique. Nature Protocols. 12: 2029-2049. PMID 28880280 DOI: 10.1038/Nprot.2017.079  0.567
2017 Alsahafi N, Richard J, Prévost J, Coutu M, Brassard N, Parsons MS, Kaufmann DE, Brockman M, Finzi A. Impaired downregulation of NKG2D ligands by Nef protein from elite controllers sensitizes HIV-1-infected cells to ADCC. Journal of Virology. PMID 28615199 DOI: 10.1128/Jvi.00109-17  0.623
2017 Richard J, Prévost J, von Bredow B, Ding S, Brassard N, Medjahed H, Coutu M, Melillo B, Bibollet-Ruche F, Hahn BH, Kaufmann DE, Smith AB, Sodroski J, Sauter D, Kirchhoff F, et al. BST-2 Expression Modulates Small CD4 Mimetic Sensitization of HIV-1-infected cells to ADCC. Journal of Virology. PMID 28331088 DOI: 10.1128/Jvi.00219-17  0.63
2017 Prévost J, Zoubchenok D, Richard J, Veillette M, Pacheco B, Coutu M, Brassard N, Parsons MS, Ruxrungtham K, Bunupuradah T, Tovanabutra S, Hwang KK, Moody MA, Haynes BF, Bonsignori M, et al. Influence of the Envelope Gp120 Phe 43 Cavity on HIV-1 Sensitivity to ADCC Responses. Journal of Virology. PMID 28100618 DOI: 10.1128/Jvi.02452-16  0.59
2016 Gohain N, Tolbert WD, Orlandi C, Richard J, Ding S, Chen X, Bonsor DA, Sundberg EJ, Lu W, Ray K, Finzi A, Lewis GK, Pazgier M. Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240. Scientific Reports. 6: 36685. PMID 27827447 DOI: 10.1038/Srep36685  0.518
2016 Richard J, Pacheco B, Gohain N, Veillette M, Ding S, Alsahafi N, Tolbert WD, Prévost J, Chapleau JP, Coutu M, Jia M, Brassard N, Park J, Courter JR, Melillo B, et al. Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins. Ebiomedicine. PMID 27633463 DOI: 10.1016/J.Ebiom.2016.09.004  0.559
2016 Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Charlebois R, Massanella M, Brassard N, Alsahafi N, Delgado GG, Routy JP, Walker BD, Finzi A, Chomont N, Kaufmann DE. Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals. Cell Host & Microbe. PMID 27545045 DOI: 10.1016/J.Chom.2016.07.015  0.626
2016 Mwimanzi P, Tietjen I, Miller SC, Shahid A, Cobarrubias K, Kinloch NN, Baraki B, Richard J, Finzi A, Fedida D, Brumme ZL, Brockman MA. A novel acylguanidine-based inhibitor of HIV-1. Journal of Virology. PMID 27512074 DOI: 10.1128/Jvi.01107-16  0.55
2016 Parsons MS, Richard J, Lee WS, Vanderven H, Grant MD, Finzi A, Kent SJ. NKG2D acts as a co-receptor for natural killer cell-mediated anti-HIV-1 antibody-dependent cellular cytotoxicity. Aids Research and Human Retroviruses. PMID 27487965 DOI: 10.1089/Aid.2016.0099  0.61
2016 Richard J, Veillette M, Ding S, Zoubchenok D, Alsahafi N, Coutu M, Brassard N, Park J, Courter JR, Melillo B, Smith AB, Shaw GM, Hahn BH, Sodroski J, Kaufmann DE, et al. Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity. Ebiomedicine. 3: 122-34. PMID 26870823 DOI: 10.1016/J.Ebiom.2015.12.004  0.625
2016 Veillette M, Richard J, Pazgier M, Lewis GK, Parsons MS, Finzi A. Role of HIV-1 Envelope Glycoproteins Conformation and Accessory Proteins on ADCC Responses. Current Hiv Research. 14: 9-23. PMID 26310828 DOI: 10.2174/1570162X13666150827093449  0.615
2015 Alsahafi N, Ding S, Richard J, Markle T, Brassard N, Walker B, Lewis GK, Kaufmann DE, Brockman MA, Finzi A. Nef proteins from HIV-1 elite controllers are inefficient at preventing ADCC. Journal of Virology. PMID 26719277 DOI: 10.1128/Jvi.02973-15  0.629
2015 Lee WS, Richard J, Lichtfuss M, Smith AB, Park J, Courter JR, Melillo BN, Sodroski JG, Kaufmann DE, Finzi A, Parsons MS, Kent SJ. Antibody-dependent cellular cytotoxicity against reactivated HIV-1-infected cells. Journal of Virology. PMID 26656700 DOI: 10.1128/Jvi.02717-15  0.626
2015 Veillette M, Richard J, Finzi A. Uncovering HIV-1-infected cells. Oncotarget. 6: 21791-2. PMID 26314853 DOI: 10.18632/Oncotarget.4974  0.61
2015 Murray MK, Teran VA, Chapleau JP, Wang B, Kim SH, LaBranche CC, Richard J, Montefiori DC, Finzi A, Yuan W. Soluble Envelope Glycoprotein Trimers from a CD4-Independent HIV-1 Elicit Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Guinea Pigs. Journal of Virology. 89: 10707-11. PMID 26246571 DOI: 10.1128/Jvi.01642-15  0.561
2015 Richard J, Veillette M, Brassard N, Iyer SS, Roger M, Martin L, Pazgier M, Schön A, Freire E, Routy JP, Smith AB, Park J, Jones DM, Courter JR, Melillo BN, et al. CD4 mimetics sensitize HIV-1-infected cells to ADCC. Proceedings of the National Academy of Sciences of the United States of America. 112: E2687-94. PMID 25941367 DOI: 10.1073/Pnas.1506755112  0.604
2015 Veillette M, Coutu M, Richard J, Batraville LA, Dagher O, Bernard N, Tremblay C, Kaufmann DE, Roger M, Finzi A. The HIV-1 gp120 CD4-bound conformation is preferentially targeted by antibody-dependent cellular cytotoxicity-mediating antibodies in sera from HIV-1-infected individuals. Journal of Virology. 89: 545-51. PMID 25339767 DOI: 10.1128/Jvi.02868-14  0.614
2015 Gooneratne SL, Richard J, Lee WS, Finzi A, Kent SJ, Parsons MS. Slaying the Trojan horse: natural killer cells exhibit robust anti-HIV-1 antibody-dependent activation and cytolysis against allogeneic T cells. Journal of Virology. 89: 97-109. PMID 25320293 DOI: 10.1128/Jvi.02461-14  0.608
2014 Batraville LA, Richard J, Veillette M, Labbé AC, Alary M, Guédou F, Kaufmann DE, Poudrier J, Finzi A, Roger M. Short communication: Anti-HIV-1 envelope immunoglobulin Gs in blood and cervicovaginal samples of Beninese commercial sex workers. Aids Research and Human Retroviruses. 30: 1145-9. PMID 25354025 DOI: 10.1089/Aid.2014.0163  0.587
2014 Veillette M, Coutu M, Richard J, Batraville LA, Désormeaux A, Roger M, Finzi A. Conformational evaluation of HIV-1 trimeric envelope glycoproteins using a cell-based ELISA assay. Journal of Visualized Experiments : Jove. 51995. PMID 25286159 DOI: 10.3791/51995  0.532
2014 Herschhorn A, Gu C, Espy N, Richard J, Finzi A, Sodroski JG. A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry. Nature Chemical Biology. 10: 845-52. PMID 25174000 DOI: 10.1038/Nchembio.1623  0.495
2014 Richard J, Veillette M, Batraville LA, Coutu M, Chapleau JP, Bonsignori M, Bernard N, Tremblay C, Roger M, Kaufmann DE, Finzi A. Flow cytometry-based assay to study HIV-1 gp120 specific antibody-dependent cellular cytotoxicity responses. Journal of Virological Methods. 208: 107-14. PMID 25125129 DOI: 10.1016/J.Jviromet.2014.08.003  0.56
2013 Richard J, Pham TN, Ishizaka Y, Cohen EA. Viral protein R upregulates expression of ULBP2 on uninfected bystander cells during HIV-1 infection of primary CD4+ T lymphocytes. Virology. 443: 248-56. PMID 23726848 DOI: 10.1016/J.Virol.2013.04.037  0.684
2011 Pham TN, Richard J, Gerard FC, Power C, Cohen ÉA. Modulation of NKG2D-mediated cytotoxic functions of natural killer cells by viral protein R from HIV-1 primary isolates. Journal of Virology. 85: 12254-61. PMID 21957298 DOI: 10.1128/Jvi.05835-11  0.64
2010 Richard J, Cohen ÉA. HIV-1 Vpu disarms natural killer cells. Cell Host & Microbe. 8: 389-91. PMID 21075348 DOI: 10.1016/J.Chom.2010.11.001  0.639
2010 Belzile JP, Richard J, Rougeau N, Xiao Y, Cohen EA. HIV-1 Vpr induces the K48-linked polyubiquitination and proteasomal degradation of target cellular proteins to activate ATR and promote G2 arrest. Journal of Virology. 84: 3320-30. PMID 20089662 DOI: 10.1128/Jvi.02590-09  0.509
2010 Richard J, Sindhu S, Pham TN, Belzile JP, Cohen EA. HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing. Blood. 115: 1354-63. PMID 20008788 DOI: 10.1182/Blood-2009-08-237370  0.694
2010 Yang YX, Guen V, Richard J, Cohen EA, Berthoux L. Cell context-dependent involvement of ATR in early stages of retroviral replication. Virology. 396: 272-9. PMID 19913868 DOI: 10.1016/J.Virol.2009.10.032  0.578
2008 Xiao Y, Chen G, Richard J, Rougeau N, Li H, Seidah NG, Cohen EA. Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases. Virology. 372: 384-97. PMID 18061232 DOI: 10.1016/J.Virol.2007.10.036  0.654
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