Jeffrey N. Agar - Publications

Affiliations: 
Chemistry Brandeis University, Waltham, MA, United States 
 Northeastern University, Boston, MA, United States 
Area:
Analytical Chemistry, General Biophysics, Biochemistry
Website:
http://www.northeastern.edu/cos/faculty/jeffrey-agar/

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, et al. How many human proteoforms are there? Nature Chemical Biology. 14: 206-214. PMID 29443976 DOI: 10.1038/nchembio.2576  1
2015 Rawlins CM, Salisbury JP, Feldman DR, Isim S, Agar NY, Luther E, Agar JN. Imaging and Mapping of Tissue Constituents at the Single-Cell Level Using MALDI MSI and Quantitative Laser Scanning Cytometry. Methods in Molecular Biology (Clifton, N.J.). 1346: 133-49. PMID 26542720 DOI: 10.1007/978-1-4939-2987-0_10  1
2015 Salisbury JP, Sîrbulescu RF, Moran BM, Auclair JR, Zupanc GKH, Agar JN. The central nervous system transcriptome of the weakly electric brown ghost knifefish (Apteronotus leptorhynchus): De novo assembly, annotation, and proteomics validation Bmc Genomics. 16. DOI: 10.1186/s12864-015-1354-2  1
2014 Salisbury JP, Liu Q, Agar JN. QUDeX-MS: hydrogen/deuterium exchange calculation for mass spectra with resolved isotopic fine structure. Bmc Bioinformatics. 15: 403. PMID 25495703 DOI: 10.1186/s12859-014-0403-1  1
2014 Dang X, Scotcher J, Wu S, Chu RK, Tolić N, Ntai I, Thomas PM, Fellers RT, Early BP, Zheng Y, Durbin KR, Leduc RD, Wolff JJ, Thompson CJ, Pan J, ... ... Agar JN, et al. The first pilot project of the consortium for top-down proteomics: a status report. Proteomics. 14: 1130-40. PMID 24644084 DOI: 10.1002/pmic.201300438  1
2014 Auclair JR, Salisbury JP, Johnson JL, Petsko GA, Ringe D, Bosco DA, Agar NY, Santagata S, Durham HD, Agar JN. Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation. Proteomics. 14: 1152-7. PMID 24634066 DOI: 10.1002/pmic.201300450  1
2014 Liu Q, Easterling ML, Agar JN. Resolving isotopic fine structure to detect and quantify natural abundance- and hydrogen/deuterium exchange-derived isotopomers. Analytical Chemistry. 86: 820-5. PMID 24328359 DOI: 10.1021/ac403365g  1
2014 Liu Q, Cobb JS, Johnson JL, Wang Q, Agar JN. Performance comparisons of nano-LC systems, electrospray sources and LC-MS-MS platforms. Journal of Chromatographic Science. 52: 120-7. PMID 23329739 DOI: 10.1093/chromsci/bms255  1
2013 Salisbury JP, Boggio KJ, Hsu YW, Quijada J, Sivachenko A, Gloeckner G, Kowalski PJ, Easterling ML, Rosbash M, Agar JN. A rapid MALDI-TOF mass spectrometry workflow for Drosophila melanogaster differential neuropeptidomics. Molecular Brain. 6: 60. PMID 24373546 DOI: 10.1186/1756-6606-6-60  1
2013 Liu X, Ide JL, Norton I, Marchionni MA, Ebling MC, Wang LY, Davis E, Sauvageot CM, Kesari S, Kellersberger KA, Easterling ML, Santagata S, Stuart DD, Alberta J, Agar JN, et al. Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging. Scientific Reports. 3: 2859. PMID 24091529 DOI: 10.1038/srep02859  1
2013 Auclair JR, Johnson JL, Liu Q, Salisbury JP, Rotunno MS, Petsko GA, Ringe D, Brown RH, Bosco DA, Agar JN. Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage. Biochemistry. 52: 6137-44. PMID 23927036 DOI: 10.1021/bi4006122  1
2013 Auclair JR, Brodkin HR, D'Aquino JA, Petsko GA, Ringe D, Agar JN. Structural consequences of cysteinylation of Cu/Zn-superoxide dismutase Biochemistry. 52: 6145-6150. PMID 23919400 DOI: 10.1021/bi400613h  1
2012 Auclair JR, Somasundaran M, Green KM, Evans JE, Schiffer CA, Ringe D, Petsko GA, Agar JN. Mass spectrometry tools for analysis of intermolecular interactions. Methods in Molecular Biology (Clifton, N.J.). 896: 387-98. PMID 22821539 DOI: 10.1007/978-1-4614-3704-8_26  1
2012 Kabashi E, Agar JN, Strong MJ, Durham HD. Impaired proteasome function in sporadic amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 13: 367-71. PMID 22632443 DOI: 10.3109/17482968.2012.686511  1
2011 Wang W, Perovic I, Chittuluru J, Kaganovich A, Nguyen LT, Liao J, Auclair JR, Johnson D, Landeru A, Simorellis AK, Ju S, Cookson MR, Asturias FJ, Agar JN, Webb BN, et al. A soluble α-synuclein construct forms a dynamic tetramer. Proceedings of the National Academy of Sciences of the United States of America. 108: 17797-802. PMID 22006323 DOI: 10.1073/pnas.1113260108  1
2011 Boggio KJ, Obasuyi E, Sugino K, Nelson SB, Agar NY, Agar JN. Recent advances in single-cell MALDI mass spectrometry imaging and potential clinical impact. Expert Review of Proteomics. 8: 591-604. PMID 21999830 DOI: 10.1586/epr.11.53  1
2011 Brodkin HR, Novak WRP, Milne AC, D'Aquino JA, Karabacak NM, Goldberg IG, Agar JN, Payne MS, Petsko GA, Ondrechen MJ, Ringe D. Evidence of the participation of remote residues in the catalytic activity of co-type nitrile hydratase from Pseudomonas putida Biochemistry. 50: 4923-4935. PMID 21473592 DOI: 10.1021/bi101761e  1
2010 Auclair JR, Boggio KJ, Petsko GA, Ringe D, Agar JN. Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis Proceedings of the National Academy of Sciences of the United States of America. 107: 21394-21399. PMID 21098299 DOI: 10.1073/pnas.1015463107  1
2010 Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nature Neuroscience. 13: 1396-403. PMID 20953194 DOI: 10.1038/nn.2660  1
2010 Li L, Karabacak NM, Cobb JS, Wang Q, Hong P, Agar JN. Memory-efficient calculation of the isotopic mass states of a molecule. Rapid Communications in Mass Spectrometry : Rcm. 24: 2689-96. PMID 20814974 DOI: 10.1002/rcm.4666  1
2010 Agar NY, Kowalski JM, Kowalski PJ, Wong JH, Agar JN. Tissue preparation for the in situ MALDI MS imaging of proteins, lipids, and small molecules at cellular resolution. Methods in Molecular Biology (Clifton, N.J.). 656: 415-31. PMID 20680605 DOI: 10.1007/978-1-60761-746-4_24  1
2010 Karabacak NM, Easterling ML, Agar NY, Agar JN. Transformative effects of higher magnetic field in Fourier transform ion cyclotron resonance mass spectrometry. Journal of the American Society For Mass Spectrometry. 21: 1218-22. PMID 20444622 DOI: 10.1016/j.jasms.2010.03.033  1
2010 Cobb JS, Easterling ML, Agar JN. Structural characterization of intact proteins is enhanced by prevalent fragmentation pathways rarely observed for peptides. Journal of the American Society For Mass Spectrometry. 21: 949-59. PMID 20303285 DOI: 10.1016/j.jasms.2010.02.009  1
2010 Agar NY, Malcolm JG, Mohan V, Yang HW, Johnson MD, Tannenbaum A, Agar JN, Black PM. Imaging of meningioma progression by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Analytical Chemistry. 82: 2621-5. PMID 20196536 DOI: 10.1021/ac100113w  1
2009 Molnar KS, Karabacak NM, Johnson JL, Wang Q, Tiwari A, Hayward LJ, Coales SJ, Hamuro Y, Agar JN. A common property of amyotrophic lateral sclerosis-associated variants: destabilization of the copper/zinc superoxide dismutase electrostatic loop. The Journal of Biological Chemistry. 284: 30965-73. PMID 19635794 DOI: 10.1074/jbc.M109.023945  1
2009 Karabacak NM, Li L, Tiwari A, Hayward LJ, Hong P, Easterling ML, Agar JN. Sensitive and specific identification of wild type and variant proteins from 8 to 669 kDa using top-down mass spectrometry. Molecular & Cellular Proteomics : McP. 8: 846-56. PMID 19074999 DOI: 10.1074/mcp.M800099-MCP200  1
2008 Li L, Kresh JA, Karabacak NM, Cobb JS, Agar JN, Hong P. A hierarchical algorithm for calculating the isotopic fine structures of molecules. Journal of the American Society For Mass Spectrometry. 19: 1867-74. PMID 18818092 DOI: 10.1016/j.jasms.2008.08.008  1
2008 Wang Q, Johnson JL, Agar NY, Agar JN. Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival. Plos Biology. 6: e170. PMID 18666828 DOI: 10.1371/journal.pbio.0060170  1
2008 Kabashi E, Agar JN, Hong Y, Taylor DM, Minotti S, Figlewicz DA, Durham HD. Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis. Journal of Neurochemistry. 105: 2353-66. PMID 18315558 DOI: 10.1111/j.1471-4159.2008.05317.x  1
2008 Morris AM, Watzky MA, Agar JN, Finke RG. Fitting neurological protein aggregation kinetic data via a 2-step, minimal/"Ockham's razor" model: the Finke-Watzky mechanism of nucleation followed by autocatalytic surface growth. Biochemistry. 47: 2413-27. PMID 18247636 DOI: 10.1021/bi701899y  1
2007 Agar NY, Yang HW, Carroll RS, Black PM, Agar JN. Matrix solution fixation: histology-compatible tissue preparation for MALDI mass spectrometry imaging. Analytical Chemistry. 79: 7416-23. PMID 17822313 DOI: 10.1021/ac071460e  1
2007 Taylor DM, Gibbs BF, Kabashi E, Minotti S, Durham HD, Agar JN. Tryptophan 32 potentiates aggregation and cytotoxicity of a copper/zinc superoxide dismutase mutant associated with familial amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 282: 16329-35. PMID 17389599 DOI: 10.1074/jbc.M610119200  1
2006 Durham HD, Kabashi E, Taylor DM, Agar JN. Motor neuron disease The Proteasome in Neurodegeneration. 247-264. DOI: 10.1007/0-387-28500-8_16  1
2005 Smith AD, Jameson GN, Dos Santos PC, Agar JN, Naik S, Krebs C, Frazzon J, Dean DR, Huynh BH, Johnson MK. NifS-mediated assembly of [4Fe-4S] clusters in the N- and C-terminal domains of the NifU scaffold protein. Biochemistry. 44: 12955-69. PMID 16185064 DOI: 10.1021/bi051257i  1
2005 Taylor DM, Kabashi E, Agar JN, Minotti S, Durham HD. Proteasome activity or expression is not altered by activation of the heat shock transcription factor Hsf1 in cultured fibroblasts or myoblasts. Cell Stress & Chaperones. 10: 230-41. PMID 16184768 DOI: 10.1379/CSC-119R.1  1
2004 Taylor DM, Minotti S, Agar JN, Durham HD. Overexpression of metallothionein protects cultured motor neurons against oxidative stress, but not mutant Cu/Zn-superoxide dismutase toxicity. Neurotoxicology. 25: 779-92. PMID 15288509 DOI: 10.1016/j.neuro.2004.02.002  1
2004 Kabashi E, Agar JN, Taylor DM, Minotti S, Durham HD. Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis. Journal of Neurochemistry. 89: 1325-35. PMID 15189335 DOI: 10.1111/j.1471-4159.2004.02453.x  1
2003 Antonicka H, Leary SC, Guercin GH, Agar JN, Horvath R, Kennaway NG, Harding CO, Jaksch M, Shoubridge EA. Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency. Human Molecular Genetics. 12: 2693-702. PMID 12928484 DOI: 10.1093/hmg/ddg284  1
2001 Krebs C, Agar JN, Smith AD, Frazzon J, Dean DR, Huynh BH, Johnson MK. IscA, an alternate scaffold for Fe-S cluster biosynthesis. Biochemistry. 40: 14069-80. PMID 11705400 DOI: 10.1021/bi015656z  1
2001 Smith AD, Agar JN, Johnson KA, Frazzon J, Amster IJ, Dean DR, Johnson MK. Sulfur transfer from IscS to IscU: the first step in iron-sulfur cluster biosynthesis. Journal of the American Chemical Society. 123: 11103-4. PMID 11686732 DOI: 10.1021/ja016757n  1
2000 Olson JW, Agar JN, Johnson MK, Maier RJ. Characterization of the NifU and NifS Fe-S cluster formation proteins essential for viability in Helicobacter pylori. Biochemistry. 39: 16213-9. PMID 11123951 DOI: 10.1021/bi001744s  1
2000 Agar JN, Krebs C, Frazzon J, Huynh BH, Dean DR, Johnson MK. IscU as a scaffold for iron-sulfur cluster biosynthesis: sequential assembly of [2Fe-2S] and [4Fe-4S] clusters in IscU. Biochemistry. 39: 7856-62. PMID 10891064 DOI: 10.1021/bi000931n  1
2000 Agar JN, Yuvaniyama P, Jack RF, Cash VL, Smith AD, Dean DR, Johnson MK. Modular organization and identification of a mononuclear iron-binding site within the NifU protein. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 5: 167-77. PMID 10819462  1
2000 Yuvaniyama P, Agar JN, Cash VL, Johnson MK, Dean DR. NifS-directed assembly of a transient [2Fe-2S] cluster within the NifU protein. Proceedings of the National Academy of Sciences of the United States of America. 97: 599-604. PMID 10639125 DOI: 10.1073/pnas.97.2.599  1
2000 Agar JN, Zheng L, Cash VL, Dean DR, Johnson MK. Role of the IscU protein in iron-sulfur cluster biosynthesis: IscS- mediated assembly of a [Fe2S2] cluster in IscU Journal of the American Chemical Society. 122: 2136-2137. DOI: 10.1021/ja9944195  1
1998 Goodwin PJ, Agar JN, Roll JT, Roberts GP, Johnson MK, Dean DR. The Azotobacter vinelandii NifEN complex contains two identical [4Fe-4S] clusters. Biochemistry. 37: 10420-8. PMID 9671511 DOI: 10.1021/bi980435n  1
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