Chen-Yong Lin - Publications

Biochemistry University of Maryland School of Medicine, Baltimore, MD, United States 
Biochemistry, Cell Biology, Molecular Biology

92 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Jia B, Thompson HA, Barndt RB, Chiu YL, Lee MJ, Lee SC, Wang JK, Tang HJ, Lin CY, Johnson MD. Mild acidity likely accelerates the physiological matriptase autoactivation process: a comparative study between spontaneous and acid-induced matriptase zymogen activation. Human Cell. PMID 32779152 DOI: 10.1007/s13577-020-00410-1  0.64
2020 Chang SC, Chiang CP, Lai CH, Du PA, Hung YS, Chen YH, Yang HY, Fang HY, Lee SP, Tang HJ, Wang JK, Johnson MD, Lin CY. Matriptase and prostasin proteolytic activities are differentially regulated in normal and wounded skin. Human Cell. PMID 32617892 DOI: 10.1007/s13577-020-00385-z  0.64
2020 Lin CY, Wang JK, Johnson MD. The spatiotemporal control of human matriptase action on its physiological substrates: a case against a direct role for matriptase proteolytic activity in profilaggrin processing and desquamation. Human Cell. PMID 32306195 DOI: 10.1007/s13577-020-00361-7  0.64
2020 Tseng CC, Jia B, Barndt RB, Dai YH, Chen YH, Du PA, Wang JK, Tang HJ, Lin CY, Johnson MD. The intracellular seven amino acid motif EEGEVFL is required for matriptase vesicle sorting and translocation to the basolateral plasma membrane. Plos One. 15: e0228874. PMID 32049977 DOI: 10.1371/journal.pone.0228874  0.64
2019 Chiu YL, Wu YY, Barndt RB, Yeo YH, Lin YW, Sytwo HP, Liu HC, Xu Y, Jia B, Wang JK, Johnson MD, Lin CY. Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2. Journal of Enzyme Inhibition and Medicinal Chemistry. 34: 692-702. PMID 30777474 DOI: 10.1080/14756366.2019.1577831  0.64
2018 Rather GM, Lin SY, Lin H, Banach-Petrosky W, Hirshfield KM, Lin CY, Johnson MD, Szekely Z, Bertino JR. Activated matriptase as a target to treat breast cancer with a drug conjugate. Oncotarget. 9: 25983-25992. PMID 29899836 DOI: 10.18632/oncotarget.25414  0.64
2018 Lee SP, Kao CY, Chang SC, Chiu YL, Chen YJ, Chen MG, Chang CC, Lin YW, Chiang CP, Wang JK, Lin CY, Johnson MD. Correction: Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin. Plos One. 13: e0198569. PMID 29852013 DOI: 10.1371/journal.pone.0198569  0.72
2018 Yamamoto K, Kawaguchi M, Shimomura T, Izumi A, Konari K, Honda A, Lin CY, Johnson MD, Yamashita Y, Fukushima T, Kataoka H. Hepatocyte growth factor activator inhibitor type-2 (HAI-2)/contributes to invasive growth of oral squamous cell carcinoma cells. Oncotarget. 9: 11691-11706. PMID 29545930 DOI: 10.18632/oncotarget.24450  0.64
2018 Chang CC, Cho SF, Chuang YW, Lin CY, Huang YF, Tyan YC. Prognostic significance of retention index of bone marrow on dual-phase 18F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with diffuse large B-cell lymphoma. Medicine. 97: e9513. PMID 29480842 DOI: 10.1097/MD.0000000000009513  0.72
2018 Lee SP, Kao CY, Chang SC, Chiu YL, Chen YJ, Chen MG, Chang CC, Lin YW, Chiang CP, Wang JK, Lin CY, Johnson MD. Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin. Plos One. 13: e0192632. PMID 29438412 DOI: 10.1371/journal.pone.0192632  0.72
2017 Chang CC, Cho SF, Chuang YW, Lin CY, Chang SM, Hsu WL, Huang YF. Prognostic significance of total metabolic tumor volume on 18F-fluorodeoxyglucose positron emission tomography/ computed tomography in patients with diffuse large B-cell lymphoma receiving rituximab-containing chemotherapy. Oncotarget. 8: 99587-99600. PMID 29245926 DOI: 10.18632/oncotarget.20447  0.72
2017 Chang CC, Cho SF, Tu HP, Lin CY, Chuang YW, Chang SM, Hsu WL, Huang YF. Tumor and bone marrow uptakes on [18F]fluorodeoxyglucose positron emission tomography/computed tomography predict prognosis in patients with diffuse large B-cell lymphoma receiving rituximab-containing chemotherapy. Medicine. 96: e8655. PMID 29137104 DOI: 10.1097/MD.0000000000008655  0.72
2017 Chuang YW, Hsu CC, Chang CC, Lin CY, Chu HL, Huang YF, Tyan YC. Multiple Bony Injuries on Bone Scan in a Case of Unsuspected Child Abuse. Case Reports in Medicine. 2017: 3015941. PMID 28740509 DOI: 10.1155/2017/3015941  0.72
2017 Shiao F, Liu LO, Huang N, Lai YJ, Barndt RJ, Tseng CC, Wang JK, Jia B, Johnson MD, Lin CY. Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2. Plos One. 12: e0170944. PMID 28125689 DOI: 10.1371/journal.pone.0170944  0.64
2016 Yang MH, Chen KC, Chiang PW, Chung TW, Chen WJ, Chu PY, Chen SC, Lu YS, Yuan CH, Wang MC, Lin CY, Huang YF, Jong SB, Lin PC, Tyan YC. Proteomic Profiling of Neuroblastoma Cells Adhesion on Hyaluronic Acid-Based Surface for Neural Tissue Engineering. Biomed Research International. 2016: 1917394. PMID 28053978 DOI: 10.1155/2016/1917394  0.72
2016 Su HC, Liang YA, Lai YJ, Chiu YL, Barndt RB, Shiao F, Chang HD, Lu DD, Huang N, Tseng CC, Wang JK, Lee MS, Johnson MD, Huang SM, Lin CY. Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner. Plos One. 11: e0167894. PMID 27936035 DOI: 10.1371/journal.pone.0167894  0.64
2016 Kanemaru A, Yamamoto K, Kawaguchi M, Fukushima T, Lin CY, Johnson MD, Camerer E, Kataoka H. Deregulated matriptase activity in oral squamous cell carcinoma promotes the infiltration of cancer-associated fibroblasts by paracrine activation of protease-activated receptor 2. International Journal of Cancer. PMID 27615543 DOI: 10.1002/ijc.30426  0.64
2016 Lai CH, Chang SC, Chen YJ, Wang YJ, Lai YJ, Chang HD, Berens EB, Johnson MD, Wang JK, Lin CY. Matriptase and prostasin are expressed in human skin in an inverse trend over the course of differentiation and are targeted to different regions of the plasma membrane. Biology Open. PMID 27543057 DOI: 10.1242/bio.019745  0.64
2016 Zoratti GL, Tanabe LM, Hyland TE, Duhaime MJ, Colombo É, Leduc R, Marsault E, Johnson MD, Lin CY, Boerner J, Lang JE, List K. Matriptase regulates c-Met mediated proliferation and invasion in inflammatory breast cancer. Oncotarget. PMID 27528224 DOI: 10.18632/oncotarget.11262  0.64
2016 Lai CH, Lai YJ, Chou FP, Chang HD, Tseng CC, Johnson MD, Wang JK, Lin CY. Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation. Plos One. 11: e0152904. PMID 27043831 DOI: 10.1371/journal.pone.0152904  0.64
2016 Chen CY, Chen CJ, Lai CH, Wu BY, Lee SP, Johnson MD, Lin CY, Wang JK. Increased matriptase zymogen activation by UV irradiation protects keratinocyte from cell death. Journal of Dermatological Science. PMID 26996264 DOI: 10.1016/j.jdermsci.2016.03.006  0.48
2016 Chen YW, Yin S, Lai YJ, Johnson MD, Lin CY. Plasminogen-dependent matriptase activation accelerates plasmin generation by differentiating primary human keratinocytes. The Journal of Investigative Dermatology. PMID 26872599 DOI: 10.1016/j.jid.2016.01.029  0.72
2015 Hsu YL, Chen YW, Lin CY, Lai YC, Chen SC, Lin ZY. Variable uptake feature of focal nodular hyperplasia in Tc-99m phytate hepatic scintigraphy/single-photon emission computed tomography-A parametric analysis. The Kaohsiung Journal of Medical Sciences. 31: 621-5. PMID 26709223 DOI: 10.1016/j.kjms.2015.09.010  0.44
2015 Lai YJ, Chang HD, Lai H, Xu Y, Shiao F, Huang N, Li L, Lee MS, Johnson MD, Wang JK, Lin CY. N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin. Plos One. 10: e0132163. PMID 26171609 DOI: 10.1371/journal.pone.0132163  0.48
2015 Najy AJ, Dyson G, Jena BP, Lin CY, Kim HC. Matriptase Activation and Shedding through PDGF-D-mediated Extracellular Acidosis. American Journal of Physiology. Cell Physiology. ajpcell.00043.2015. PMID 26157007 DOI: 10.1152/ajpcell.00043.2015  0.48
2015 Lin CY, Hsieh HY, Pitt WG, Huang CY, Tseng IC, Yeh CK, Wei KC, Liu HL. Focused ultrasound-induced blood-brain barrier opening for non-viral, non-invasive, and targeted gene delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 212: 1-9. PMID 26071631 DOI: 10.1016/j.jconrel.2015.06.010  0.32
2015 Chang YL, Liu CT, Chu HL, Chen YW, Lin CY. Incidental Finding of Urinary Bladder Retention on the 99mTc-Labeled Red Blood Cells Subcutaneous Radionuclide Venography. Clinical Nuclear Medicine. PMID 26018701 DOI: 10.1097/RLU.0000000000000820  0.72
2015 Kawaguchi M, Kanemaru A, Sawaguchi A, Yamamoto K, Baba T, Lin CY, Johnson MD, Fukushima T, Kataoka H. Hepatocyte Growth Factor Activator Inhibitor Type 1 Maintains the Assembly of Keratin into Desmosomes in Keratinocytes by Regulating Protease-Activated Receptor 2-Dependent p38 Signaling. The American Journal of Pathology. 185: 1610-23. PMID 25842366 DOI: 10.1016/j.ajpath.2015.02.009  0.48
2015 Chang HH, Xu Y, Lai H, Yang X, Tseng CC, Lai YJ, Pan Y, Zhou E, Johnson MD, Wang JK, Lin CY. Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells. Plos One. 10: e0120489. PMID 25786220 DOI: 10.1371/journal.pone.0120489  0.48
2014 Chang CC, Tu HP, Chen YW, Lin CY, Hou MF. Tumour and lymph node uptakes on dual-phased 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography correlate with prognostic parameters in breast cancer. The Journal of International Medical Research. 42: 1209-21. PMID 25339454 DOI: 10.1177/0300060514549785  0.72
2014 Wang JK, Teng IJ, Lo TJ, Moore S, Yeo YH, Teng YC, Kaul M, Chen CC, Zuo AH, Chou FP, Yang X, Tseng IC, Johnson MD, Lin CY. Matriptase autoactivation is tightly regulated by the cellular chemical environments. Plos One. 9: e93899. PMID 24705933 DOI: 10.1371/journal.pone.0093899  0.48
2014 Chu LL, Xu Y, Yang JR, Hu YA, Chang HH, Lai HY, Tseng CC, Wang HY, Johnson MD, Wang JK, Lin CY. Human cancer cells retain modest levels of enzymatically active matriptase only in extracellular milieu following induction of zymogen activation. Plos One. 9: e92244. PMID 24663123 DOI: 10.1371/journal.pone.0092244  0.48
2014 Ye J, Kawaguchi M, Haruyama Y, Kanemaru A, Fukushima T, Yamamoto K, Lin CY, Kataoka H. Loss of hepatocyte growth factor activator inhibitor type 1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model. Cancer Science. 105: 44-51. PMID 24147538 DOI: 10.1111/cas.12306  0.56
2014 Wu BY, Lee SP, Hsiao HC, Chiu H, Chen CY, Yeo YH, Lee HS, Chen YW, Kaul M, Kataoka H, Johnson MD, Wang JK, Lin CY. Matriptase expression and zymogen activation in human pilosebaceous unit. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 62: 50-9. PMID 24004857 DOI: 10.1369/0022155413505599  0.72
2014 Chen YW, Wang JK, Chou FP, Wu BY, Hsiao HC, Chiu H, Xu Z, Baksh AN, Shi G, Kaul M, Barndt R, Shanmugam VK, Johnson MD, Lin CY. Matriptase regulates proliferation and early, but not terminal, differentiation of human keratinocytes. The Journal of Investigative Dermatology. 134: 405-14. PMID 23900022 DOI: 10.1038/jid.2013.320  0.48
2013 Chou FP, Chen YW, Zhao XF, Xu-Monette ZY, Young KH, Gartenhaus RB, Wang JK, Kataoka H, Zuo AH, Barndt RJ, Johnson M, Lin CY. Imbalanced matriptase pericellular proteolysis contributes to the pathogenesis of malignant B-cell lymphomas. The American Journal of Pathology. 183: 1306-17. PMID 24070417 DOI: 10.1016/j.ajpath.2013.06.024  0.72
2013 Lin CY, Huo C, Kuo LK, Hiipakka RA, Jones RB, Lin HP, Hung Y, Su LC, Tseng JC, Kuo YY, Wang YL, Fukui Y, Kao YH, Kokontis JM, Yeh CC, et al. Cholestane-3β, 5α, 6β-triol suppresses proliferation, migration, and invasion of human prostate cancer cells. Plos One. 8: e65734. PMID 23785446 DOI: 10.1371/journal.pone.0065734  0.72
2013 Chen YW, Xu Z, Baksh AN, Wang JK, Chen CY, Swanson R, Olson ST, Kataoka H, Johnson MD, Lin CY. Antithrombin regulates matriptase activity involved in plasmin generation, syndecan shedding, and HGF activation in keratinocytes. Plos One. 8: e62826. PMID 23675430 DOI: 10.1371/journal.pone.0062826  0.72
2013 Uen YH, Lin KY, Sun DP, Liao CC, Hsieh MS, Huang YK, Chen YW, Huang PH, Chen WJ, Tai CC, Lee KW, Chen YC, Lin CY. Comparative proteomics, network analysis and post-translational modification identification reveal differential profiles of plasma Con A-bound glycoprotein biomarkers in gastric cancer. Journal of Proteomics. 83: 197-213. PMID 23541716 DOI: 10.1016/j.jprot.2013.03.007  0.72
2013 Lin CY, Chen YW, Chang CC, Yang WC, Huang CJ, Hou MF. Bone metastasis versus bone marrow metastasis? Integration of diagnosis by (18)F-fluorodeoxyglucose positron emission/computed tomography in advanced malignancy with super bone scan: two case reports and literature review. The Kaohsiung Journal of Medical Sciences. 29: 229-33. PMID 23541269 DOI: 10.1016/j.kjms.2012.08.038  0.72
2013 Chuang YW, Hsu CC, Huang YF, Lin HF, Chang CC, Lin CY, Tyan YC. Brain perfusion SPECT in patients with Behçet's disease. Journal of Neuroradiology. Journal De Neuroradiologie. 40: 288-93. PMID 23433907 DOI: 10.1016/j.neurad.2013.01.001  0.72
2013 Larsen BR, Steffensen SD, Nielsen NV, Friis S, Godiksen S, Bornholdt J, Soendergaard C, Nonboe AW, Andersen MN, Poulsen SS, Szabo R, Bugge TH, Lin CY, Skovbjerg H, Jensen JK, et al. Hepatocyte growth factor activator inhibitor-2 prevents shedding of matriptase. Experimental Cell Research. 319: 918-29. PMID 23333561 DOI: 10.1016/j.yexcr.2013.01.008  0.48
2012 Kohama K, Kawaguchi M, Fukushima T, Lin CY, Kataoka H. Regulation of pericellular proteolysis by hepatocyte growth factor activator inhibitor type 1 (HAI-1) in trophoblast cells. Human Cell. 25: 100-10. PMID 23248048 DOI: 10.1007/s13577-012-0055-2  0.56
2012 Chang CC, Cho SF, Chen YW, Tu HP, Lin CY, Chang CS. SUV on dual-phase FDG PET/CT correlates with the Ki-67 proliferation index in patients with newly diagnosed non-Hodgkin lymphoma. Clinical Nuclear Medicine. 37: e189-95. PMID 22785526 DOI: 10.1097/RLU.0b013e318251e16e  0.72
2012 Baba T, Kawaguchi M, Fukushima T, Sato Y, Orikawa H, Yorita K, Tanaka H, Lin CY, Sakoda S, Kataoka H. Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells' invasiveness. The Journal of Pathology. 228: 181-92. PMID 22262311 DOI: 10.1002/path.3993  0.56
2012 Xu H, Xu Z, Tseng IC, Chou FP, Chen YW, Wang JK, Johnson MD, Kataoka H, Lin CY. Mechanisms for the control of matriptase activity in the absence of sufficient HAI-1. American Journal of Physiology. Cell Physiology. 302: C453-62. PMID 22031598 DOI: 10.1152/ajpcell.00344.2011  0.72
2011 Xu Z, Chen YW, Battu A, Wilder P, Weber D, Yu W, Mackerell AD, Chen LM, Chai KX, Johnson MD, Lin CY. Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade. Journal of Medicinal Chemistry. 54: 7567-78. PMID 21966950 DOI: 10.1021/jm200920s  0.48
2011 Yuan S, Yu SL, Chen HY, Hsu YC, Su KY, Chen HW, Chen CY, Yu CJ, Shih JY, Chang YL, Cheng CL, Hsu CP, Hsia JY, Lin CY, Wu G, et al. Clustered genomic alterations in chromosome 7p dictate outcomes and targeted treatment responses of lung adenocarcinoma with EGFR-activating mutations. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3435-42. PMID 21810691 DOI: 10.1200/JCO.2011.35.3979  0.48
2011 Chou FP, Xu H, Lee MS, Chen YW, Richards OX, Swanson R, Olson ST, Johnson MD, Lin CY. Matriptase is inhibited by extravascular antithrombin in epithelial cells but not in most carcinoma cells. American Journal of Physiology. Cell Physiology. 301: C1093-103. PMID 21795523 DOI: 10.1152/ajpcell.00122.2011  0.72
2011 Chen YW, Lin CY, Hou PN, Lee CS, Hou MF, Tsai EM. Whole-body FDG PET/CT in diagnosis of internal mammary nodal metastasis of ovarian carcinosarcoma. Clinical Nuclear Medicine. 36: 460-1. PMID 21552025 DOI: 10.1097/RLU.0b013e31820aa165  0.72
2011 Chen CJ, Wu BY, Tsao PI, Chen CY, Wu MH, Chan YL, Lee HS, Johnson MD, Eckert RL, Chen YW, Chou F, Wang JK, Lin CY. Increased matriptase zymogen activation in inflammatory skin disorders. American Journal of Physiology. Cell Physiology. 300: C406-15. PMID 21123732 DOI: 10.1152/ajpcell.00403.2010  0.48
2010 Wu SR, Cheng TS, Chen WC, Shyu HY, Ko CJ, Huang HP, Teng CH, Lin CH, Johnson MD, Lin CY, Lee MS. Matriptase is involved in ErbB-2-induced prostate cancer cell invasion. The American Journal of Pathology. 177: 3145-58. PMID 20971737 DOI: 10.2353/ajpath.2010.100228  0.64
2010 Chen YW, Wang JK, Chou FP, Chen CY, Rorke EA, Chen LM, Chai KX, Eckert RL, Johnson MD, Lin CY. Regulation of the matriptase-prostasin cell surface proteolytic cascade by hepatocyte growth factor activator inhibitor-1 during epidermal differentiation. The Journal of Biological Chemistry. 285: 31755-62. PMID 20696767 DOI: 10.1074/jbc.M110.150367  0.48
2010 Jiang H, Jans R, Xu W, Rorke EA, Lin CY, Chen YW, Fang S, Zhong Y, Eckert RL. Type I transglutaminase accumulation in the endoplasmic reticulum may be an underlying cause of autosomal recessive congenital ichthyosis. The Journal of Biological Chemistry. 285: 31634-46. PMID 20663883 DOI: 10.1074/jbc.M110.128645  0.48
2010 Chen YW, Lee MS, Lucht A, Chou FP, Huang W, Havighurst TC, Kim K, Wang JK, Antalis TM, Johnson MD, Lin CY. TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate cancer cells. The American Journal of Pathology. 176: 2986-96. PMID 20382709 DOI: 10.2353/ajpath.2010.090665  0.48
2010 Camerer E, Barker A, Duong DN, Ganesan R, Kataoka H, Cornelissen I, Darragh MR, Hussain A, Zheng YW, Srinivasan Y, Brown C, Xu SM, Regard JB, Lin CY, Craik CS, et al. Local protease signaling contributes to neural tube closure in the mouse embryo. Developmental Cell. 18: 25-38. PMID 20152175 DOI: 10.1016/j.devcel.2009.11.014  0.48
2010 Buzza MS, Netzel-Arnett S, Shea-Donohue T, Zhao A, Lin CY, List K, Szabo R, Fasano A, Bugge TH, Antalis TM. Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine. Proceedings of the National Academy of Sciences of the United States of America. 107: 4200-5. PMID 20142489 DOI: 10.1073/pnas.0903923107  0.48
2010 Tseng IC, Xu H, Chou FP, Li G, Vazzano AP, Kao JP, Johnson MD, Lin CY. Matriptase activation, an early cellular response to acidosis. The Journal of Biological Chemistry. 285: 3261-70. PMID 19940125 DOI: 10.1074/jbc.M109.055640  0.64
2010 Chen M, Chen LM, Lin CY, Chai KX. Hepsin activates prostasin and cleaves the extracellular domain of the epidermal growth factor receptor. Molecular and Cellular Biochemistry. 337: 259-66. PMID 19911255 DOI: 10.1007/s11010-009-0307-y  0.68
2009 Wang JK, Lee MS, Tseng IC, Chou FP, Chen YW, Fulton A, Lee HS, Chen CJ, Johnson MD, Lin CY. Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition. American Journal of Physiology. Cell Physiology. 297: C459-70. PMID 19535514 DOI: 10.1152/ajpcell.00201.2009  0.72
2009 Li MH, Sanchez T, Yamase H, Hla T, Oo ML, Pappalardo A, Lynch KR, Lin CY, Ferrer F. S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor. Cancer Letters. 276: 171-9. PMID 19131156 DOI: 10.1016/j.canlet.2008.11.025  0.48
2009 Chen M, Ni J, Chang HC, Lin CY, Muyan M, Yeh S. CCDC62/ERAP75 functions as a coactivator to enhance estrogen receptor beta-mediated transactivation and target gene expression in prostate cancer cells. Carcinogenesis. 30: 841-50. PMID 19126643 DOI: 10.1093/carcin/bgn288  0.68
2008 Estrada R, Zeng Q, Lu H, Sarojini H, Lee JF, Mathis SP, Sanchez T, Wang E, Kontos CD, Lin CY, Hla T, Haribabu B, Lee MJ. Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells. The Journal of Biological Chemistry. 283: 30363-75. PMID 18765664 DOI: 10.1074/jbc.M804392200  0.48
2008 Tseng IC, Chou FP, Su SF, Oberst M, Madayiputhiya N, Lee MS, Wang JK, Sloane DE, Johnson M, Lin CY. Purification from human milk of matriptase complexes with secreted serpins: mechanism for inhibition of matriptase other than HAI-1. American Journal of Physiology. Cell Physiology. 295: C423-31. PMID 18550704 DOI: 10.1152/ajpcell.00164.2008  0.64
2008 Wang L, Lee JF, Lin CY, Lee MJ. Rho GTPases mediated integrin alpha v beta 3 activation in sphingosine-1-phosphate stimulated chemotaxis of endothelial cells. Histochemistry and Cell Biology. 129: 579-88. PMID 18247041 DOI: 10.1007/s00418-008-0389-8  0.48
2008 Chen M, Chen LM, Lin CY, Chai KX. The epidermal growth factor receptor (EGFR) is proteolytically modified by the Matriptase-Prostasin serine protease cascade in cultured epithelial cells. Biochimica Et Biophysica Acta. 1783: 896-903. PMID 18054338 DOI: 10.1016/j.bbamcr.2007.10.019  0.68
2008 Lin CY, Tseng IC, Chou FP, Su SF, Chen YW, Johnson MD, Dickson RB. Zymogen activation, inhibition, and ectodomain shedding of matriptase. Frontiers in Bioscience : a Journal and Virtual Library. 13: 621-35. PMID 17981575  0.72
2007 Chen M, Fu YY, Lin CY, Chen LM, Chai KX. Prostasin induces protease-dependent and independent molecular changes in the human prostate carcinoma cell line PC-3. Biochimica Et Biophysica Acta. 1773: 1133-40. PMID 17532063 DOI: 10.1016/j.bbamcr.2007.04.013  0.68
2007 Lee MS, Tseng IC, Wang Y, Kiyomiya K, Johnson MD, Dickson RB, Lin CY. Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain. American Journal of Physiology. Cell Physiology. 293: C95-105. PMID 17344310 DOI: 10.1152/ajpcell.00611.2006  0.64
2007 Oo ML, Thangada S, Wu MT, Liu CH, Macdonald TL, Lynch KR, Lin CY, Hla T. Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor. The Journal of Biological Chemistry. 282: 9082-9. PMID 17237497 DOI: 10.1074/jbc.M610318200  0.48
2006 Jin X, Yagi M, Akiyama N, Hirosaki T, Higashi S, Lin CY, Dickson RB, Kitamura H, Miyazaki K. Matriptase activates stromelysin (MMP-3) and promotes tumor growth and angiogenesis. Cancer Science. 97: 1327-34. PMID 16999819 DOI: 10.1111/j.1349-7006.2006.00328.x  0.6
2006 Netzel-Arnett S, Currie BM, Szabo R, Lin CY, Chen LM, Chai KX, Antalis TM, Bugge TH, List K. Evidence for a matriptase-prostasin proteolytic cascade regulating terminal epidermal differentiation. The Journal of Biological Chemistry. 281: 32941-5. PMID 16980306 DOI: 10.1074/jbc.C600208200  0.48
2006 Saleem M, Adhami VM, Zhong W, Longley BJ, Lin CY, Dickson RB, Reagan-Shaw S, Jarrard DF, Mukhtar H. A novel biomarker for staging human prostate adenocarcinoma: overexpression of matriptase with concomitant loss of its inhibitor, hepatocyte growth factor activator inhibitor-1. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 217-27. PMID 16492908 DOI: 10.1158/1055-9965.EPI-05-0737  0.6
2006 Kiyomiya K, Lee MS, Tseng IC, Zuo H, Barndt RJ, Johnson MD, Dickson RB, Lin CY. Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells. American Journal of Physiology. Cell Physiology. 291: C40-9. PMID 16467405 DOI: 10.1152/ajpcell.00351.2005  0.64
2006 Ito Y, Akinaga A, Yamanaka K, Nakagawa T, Kondo A, Dickson RB, Lin CY, Miyauchi A, Taniguchi N, Miyoshi E. Co-expression of matriptase and N-acetylglucosaminyltransferase V in thyroid cancer tissues--its possible role in prolonged stability in vivo by aberrant glycosylation. Glycobiology. 16: 368-74. PMID 16464868 DOI: 10.1093/glycob/cwj084  0.6
2006 Ahmed S, Jin X, Yagi M, Yasuda C, Sato Y, Higashi S, Lin CY, Dickson RB, Miyazaki K. Identification of membrane-bound serine proteinase matriptase as processing enzyme of insulin-like growth factor binding protein-related protein-1 (IGFBP-rP1/angiomodulin/mac25). The Febs Journal. 273: 615-27. PMID 16420484 DOI: 10.1111/j.1742-4658.2005.05094.x  0.6
2005 Siddiqui SF, Pawelek J, Handerson T, Lin CY, Dickson RB, Rimm DL, Camp RL. Coexpression of β1,6-N-acetylglucosaminyltransferase V glycoprotein substrates defines aggressive breast cancers with poor outcome Cancer Epidemiology Biomarkers and Prevention. 14: 2517-2523. PMID 16284372 DOI: 10.1158/1055-9965.EPI-05-0464  0.48
2005 Lee JW, Yong Song S, Choi JJ, Lee SJ, Kim BG, Park CS, Lee JH, Lin CY, Dickson RB, Bae DS. Increased expression of matriptase is associated with histopathologic grades of cervical neoplasia. Human Pathology. 36: 626-33. PMID 16021568 DOI: 10.1016/j.humpath.2005.03.003  0.6
2005 Jin X, Hirosaki T, Lin CY, Dickson RB, Higashi S, Kitamura H, Miyazaki K. Production of soluble matriptase by human cancer cell lines and cell surface activation of its zymogen by trypsin. Journal of Cellular Biochemistry. 95: 632-47. PMID 15832373 DOI: 10.1002/jcb.20418  0.6
2005 Oberst MD, Chen LY, Kiyomiya K, Williams CA, Lee MS, Johnson MD, Dickson RB, Lin CY. HAI-1 regulates activation and expression of matriptase, a membrane-bound serine protease. American Journal of Physiology. Cell Physiology. 289: C462-70. PMID 15800053 DOI: 10.1152/ajpcell.00076.2005  0.64
2005 Lee MS, Kiyomiya K, Benaud C, Dickson RB, Lin CY. Simultaneous activation and hepatocyte growth factor activator inhibitor 1-mediated inhibition of matriptase induced at activation foci in human mammary epithelial cells. American Journal of Physiology. Cell Physiology. 288: C932-41. PMID 15590895 DOI: 10.1152/ajpcell.00497.2004  0.64
2004 Hung RJ, Hsu IaW, Dreiling JL, Lee MJ, Williams CA, Oberst MD, Dickson RB, Lin CY. Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts. American Journal of Physiology. Cell Physiology. 286: C1159-69. PMID 15075215 DOI: 10.1152/ajpcell.00400.2003  0.6
2004 Suzuki M, Kobayashi H, Kanayama N, Saga Y, Suzuki M, Lin CY, Dickson RB, Terao T. Inhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinase. The Journal of Biological Chemistry. 279: 14899-908. PMID 14747469 DOI: 10.1074/jbc.M313130200  0.6
2004 Ihara S, Miyoshi E, Nakahara S, Sakiyama H, Ihara H, Akinaga A, Honke K, Dickson RB, Lin CY, Taniguchi N. Addition of beta1-6 GlcNAc branching to the oligosaccharide attached to Asn 772 in the serine protease domain of matriptase plays a pivotal role in its stability and resistance against trypsin. Glycobiology. 14: 139-46. PMID 14551220 DOI: 10.1093/glycob/cwh013  0.6
2003 Oberst MD, Singh B, Ozdemirli M, Dickson RB, Johnson MD, Lin CY. Characterization of matriptase expression in normal human tissues. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 51: 1017-25. PMID 12871983  0.64
2003 Johnson MD, Oberst MD, Lin CY, Dickson RB. Possible role of matriptase in the diagnosis of ovarian cancer. Expert Review of Molecular Diagnostics. 3: 331-8. PMID 12779007 DOI: 10.1586/14737159.3.3.331  0.64
2003 Oberst MD, Williams CA, Dickson RB, Johnson MD, Lin CY. The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor. The Journal of Biological Chemistry. 278: 26773-9. PMID 12738778 DOI: 10.1074/jbc.M304282200  0.64
2003 Kang JY, Dolled-Filhart M, Ocal IT, Singh B, Lin CY, Dickson RB, Rimm DL, Camp RL. Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer. Cancer Research. 63: 1101-5. PMID 12615728  0.6
2002 Benaud CM, Oberst M, Dickson RB, Lin CY. Deregulated activation of matriptase in breast cancer cells. Clinical & Experimental Metastasis. 19: 639-49. PMID 12498394 DOI: 10.1023/A:1020985632550  0.48
2002 Oberst MD, Johnson MD, Dickson RB, Lin CY, Singh B, Stewart M, Williams A, al-Nafussi A, Smyth JF, Gabra H, Sellar GC. Expression of the serine protease matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: correlation with clinical outcome and tumor clinicopathological parameters. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 1101-7. PMID 11948120  0.64
2002 Ihara S, Miyoshi E, Ko JH, Murata K, Nakahara S, Honke K, Dickson RB, Lin CY, Taniguchi N. Prometastatic effect of N-acetylglucosaminyltransferase V is due to modification and stabilization of active matriptase by adding beta 1-6 GlcNAc branching. The Journal of Biological Chemistry. 277: 16960-7. PMID 11864986 DOI: 10.1074/jbc.M200673200  0.6
2002 Benaud C, Oberst M, Hobson JP, Spiegel S, Dickson RB, Lin CY. Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase. The Journal of Biological Chemistry. 277: 10539-46. PMID 11792696 DOI: 10.1074/jbc.M109064200  0.6
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