William S. Hancock - Publications

Affiliations: 
2002- Chemistry Northeastern University, Boston, MA, United States 
Area:
Proteomics, Biotechnology
Website:
http://cbi.mit.edu/research-overview/bioman/bioman-news-events/2012-biomanufacturing-summit-details/william-s-hancock-phd/

193 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang Y, Liu D, Crowell LE, Love KR, Wu SL, Hancock WS. The application of HPLC/MS analysis with a multi-enzyme digest strategy to characterize different interferon product variants produced from Pichia pastoris. Amino Acids. PMID 31446487 DOI: 10.1007/S00726-019-02772-9  0.321
2018 Crowell LE, Lu AE, Love KR, Stockdale A, Timmick SM, Wu D, Wang YA, Doherty W, Bonnyman A, Vecchiarello N, Goodwine C, Bradbury L, Brady JR, Clark JJ, Colant NA, ... ... Hancock WS, et al. On-demand manufacturing of clinical-quality biopharmaceuticals. Nature Biotechnology. PMID 30272677 DOI: 10.1038/Nbt.4262  0.304
2018 Herrington WF, Singh GP, Wu D, Barone PW, Hancock W, Ram RJ. Optical Detection of Degraded Therapeutic Proteins. Scientific Reports. 8: 5089. PMID 29572496 DOI: 10.1038/S41598-018-23409-Z  0.316
2017 Wang YA, Wu D, Auclair JR, Salisbury JP, Sarin R, Tang Y, Mozdzierz NJ, Shah K, Zhang AF, Wu SL, Agar JN, Love JC, Love KR, Hancock WS. Integrated bottom-up and top-down liquid chromatography-mass spectrometry (LC-MS) for characterization of recombinant human growth hormone degradation products. Analytical Chemistry. PMID 29096433 DOI: 10.1021/Acs.Analchem.7B03026  0.419
2017 Na K, Shin H, Cho JY, Jung SH, Lim J, Lim JS, Kim EA, Kim HS, Kang AR, Kim JH, Shin JM, Jeong SK, Kim CY, Park JY, Chung HM, ... ... Hancock WS, et al. A systematic proteogenomic approach to exploring a novel function for NHERF1 in human reproductive disorder: lessons for exploring missing proteins. Journal of Proteome Research. PMID 28960081 DOI: 10.1021/Acs.Jproteome.7B00146  0.4
2017 Liu Y, Wu SL, Love KR, Hancock WS. Characterization of Site-Specific glycosylation in Influenza A Virus Hemagglutinin produced by Spodoptera frugiperda insect cell line. Analytical Chemistry. PMID 28921955 DOI: 10.1021/Acs.Analchem.7B03025  0.354
2017 Higdon R, Kala J, Wilkins D, Yan JF, Sethi MK, Lin L, Liu S, Montague E, Janko I, Choiniere J, Kolker N, Hancock WS, Kolker E, Fanayan S. Integrated Proteomic and Transcriptomic-Based Approaches to Identifying Signature Biomarkers and Pathways for Elucidation of Daoy and UW228 Subtypes. Proteomes. 5. PMID 28248256 DOI: 10.3390/Proteomes5010005  0.393
2016 Sethi MK, Hancock WS, Fanayan S. Identifying N-Glycan Biomarkers in Colorectal Cancer by Mass Spectrometry. Accounts of Chemical Research. PMID 27653471 DOI: 10.1021/Acs.Accounts.6B00193  0.403
2016 Ouyang W, Ko SH, Wu D, Wang AY, Barone PW, Hancock WS, Han J. Rapid Assessment of Therapeutic Proteins Using Molecular Charge Modulation Enhanced Electrokinetic Concentration Assays. Analytical Chemistry. PMID 27624735 DOI: 10.1021/Acs.Analchem.6B02517  0.31
2016 Deutsch EW, Overall CM, Van Eyk JE, Baker MS, Paik YK, Weintraub ST, Lane L, Martens L, Vandenbrouck Y, Kusebauch U, Hancock WS, Hermjakob H, Aebersold R, Moritz RL, Omenn GS. Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1. Journal of Proteome Research. 15: 3961-3970. PMID 27490519 DOI: 10.1021/Acs.Jproteome.6B00392  0.345
2016 Kim S, Lee HJ, Hahm JH, Jeong SK, Park DH, Hancock WS, Paik YK. Quantitative Profiling Identifies Potential Regulatory Proteins Involved in Developmental from Dauer Stage to L4 Stage in Caenorhabditis elegans. Journal of Proteome Research. PMID 26751275 DOI: 10.1021/Acs.Jproteome.5B00884  0.342
2015 Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS. A systems proteomics view of the endogenous human claudin protein family. Journal of Proteome Research. PMID 26680015 DOI: 10.1021/Acs.Jproteome.5B00769  0.353
2015 Yan JF, Kim H, Jeong SK, Lee HJ, Sethi MK, Lee LY, Beavis RC, Im H, Snyder MP, Hofree M, Ideker T, Wu SL, Paik YK, Fanayan S, Hancock WS. Integrated Proteomic and Genomic Analysis of Gastric Cancer Patient Tissues. Journal of Proteome Research. PMID 26435392 DOI: 10.1021/Acs.Jproteome.5B00827  0.321
2015 Paik YK, Omenn GS, Overall CM, Deutsch EW, Hancock WS. Recent Advances in the Chromosome-Centric Human Proteome Project: Missing Proteins in the Spot Light. Journal of Proteome Research. 14: 3409-14. PMID 26337862 DOI: 10.1021/Acs.Jproteome.5B00785  0.307
2015 Cho JY, Lee HJ, Jeong SK, Kim KY, Kwon KH, Yoo JS, Omenn GS, Baker MS, Hancock WS, Paik YK. Combination of Multiple Spectral Libraries Improves the Current Search Methods Used to Identify Missing Proteins in the Chromosome-Centric Human Proteome Project. Journal of Proteome Research. PMID 26330117 DOI: 10.1021/Acs.Jproteome.5B00578  0.417
2015 Jeong SK, Hancock WS, Paik YK. GenomewidePDB 2.0: A Newly Upgraded Versatile Proteogenomic Database for the Chromosome-Centric Human Proteome Project. Journal of Proteome Research. 14: 3710-9. PMID 26272709 DOI: 10.1021/Acs.Jproteome.5B00541  0.398
2015 Sethi MK, Kim H, Park CK, Baker MS, Paik YK, Packer NH, Hancock WS, Fanayan S, Thaysen-Andersen M. In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation. Glycobiology. PMID 26085185 DOI: 10.1093/Glycob/Cwv042  0.32
2015 Horvatovich P, Lundberg EK, Chen YJ, Sung TY, He F, Nice EC, Goode RJ, Yu S, Ranganathan S, Baker MS, Domont GB, Velasquez E, Li D, Liu S, Wang Q, ... ... Hancock WS, et al. Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project. Journal of Proteome Research. PMID 26076068 DOI: 10.1021/Pr5013009  0.367
2015 Sethi MK, Thaysen-Andersen M, Kim H, Park CK, Baker MS, Packer NH, Paik YK, Hancock WS, Fanayan S. Quantitative proteomic analysis of paired colorectal cancer and non-tumorigenic tissues reveals signature proteins and perturbed pathways involved in CRC progression and metastasis. Journal of Proteomics. PMID 26054784 DOI: 10.1016/J.Jprot.2015.05.037  0.374
2015 Gbormittah FO, Bones J, Hincapie M, Tousi F, Hancock WS, Iliopoulos O. Clusterin glycopeptide variant characterization reveals significant site-specific glycan changes in the plasma of clear cell renal cell carcinoma. Journal of Proteome Research. 14: 2425-36. PMID 25855029 DOI: 10.1021/Pr501104J  0.772
2015 Nilsson CL, Mostovenko E, Lichti CF, Ruggles K, Fenyö D, Rosenbloom KR, Hancock WS, Paik YK, Omenn GS, LaBaer J, Kroes RA, Uhlén M, Hober S, Végvári Á, Andrén PE, et al. Use of ENCODE resources to characterize novel proteoforms and missing proteins in the human proteome. Journal of Proteome Research. 14: 603-8. PMID 25369122 DOI: 10.1021/Pr500564Q  0.42
2014 Gbormittah FO, Hincapie M, Hancock WS. Development of an improved fractionation of the human plasma proteome by a combination of abundant proteins depletion and multi-lectin affinity chromatography. Bioanalysis. 6: 2537-48. PMID 25411697 DOI: 10.4155/Bio.14.217  0.807
2014 Zhang AF, Wu SL, Jung Y, Qin S, Hancock WS, Kreidberg JA. Identification of novel glycans with disialylated structures in α3 integrin from mouse kidney cells with the phenotype of polycystic kidney disease. Journal of Proteome Research. 13: 4901-9. PMID 25300029 DOI: 10.1021/Pr5009702  0.304
2014 Lee LY, Thaysen-Andersen M, Baker MS, Packer NH, Hancock WS, Fanayan S. Comprehensive N-glycome profiling of cultured human epithelial breast cells identifies unique secretome N-glycosylation signatures enabling tumorigenic subtype classification. Journal of Proteome Research. 13: 4783-95. PMID 25210975 DOI: 10.1021/Pr500331M  0.346
2014 Gbormittah FO, Lee LY, Taylor K, Hancock WS, Iliopoulos O. Comparative studies of the proteome, glycoproteome, and N-glycome of clear cell renal cell carcinoma plasma before and after curative nephrectomy. Journal of Proteome Research. 13: 4889-900. PMID 25184692 DOI: 10.1021/Pr500591E  0.799
2014 Lee MJ, Na K, Jeong SK, Lim JS, Kim SA, Lee MJ, Song SY, Kim H, Hancock WS, Paik YK. Identification of human complement factor B as a novel biomarker candidate for pancreatic ductal adenocarcinoma. Journal of Proteome Research. 13: 4878-88. PMID 25057901 DOI: 10.1021/Pr5002719  0.331
2014 Pinto SM, Manda SS, Kim MS, Taylor K, Selvan LD, Balakrishnan L, Subbannayya T, Yan F, Prasad TS, Gowda H, Lee C, Hancock WS, Pandey A. Functional annotation of proteome encoded by human chromosome 22. Journal of Proteome Research. 13: 2749-60. PMID 24669763 DOI: 10.1021/Pr401169D  0.566
2014 Lee HJ, Cha HJ, Lim JS, Lee SH, Song SY, Kim H, Hancock WS, Yoo JS, Paik YK. Abundance-ratio-based semiquantitative analysis of site-specific N-linked glycopeptides present in the plasma of hepatocellular carcinoma patients. Journal of Proteome Research. 13: 2328-38. PMID 24628331 DOI: 10.1021/Pr4011519  0.32
2014 Islam MT, Garg G, Hancock WS, Risk BA, Baker MS, Ranganathan S. Protannotator: a semiautomated pipeline for chromosome-wise functional annotation of the "missing" human proteome. Journal of Proteome Research. 13: 76-83. PMID 24313344 DOI: 10.1021/Pr400794X  0.378
2014 Gbormittah FO, Haab BB, Partyka K, Garcia-Ott C, Hancapie M, Hancock WS. Characterization of glycoproteins in pancreatic cyst fluid using a high-performance multiple lectin affinity chromatography platform. Journal of Proteome Research. 13: 289-99. PMID 24303806 DOI: 10.1021/Pr400813U  0.802
2014 Sethi MK, Thaysen-Andersen M, Smith JT, Baker MS, Packer NH, Hancock WS, Fanayan S. Comparative N-glycan profiling of colorectal cancer cell lines reveals unique bisecting GlcNAc and α-2,3-linked sialic acid determinants are associated with membrane proteins of the more metastatic/aggressive cell lines. Journal of Proteome Research. 13: 277-88. PMID 24295106 DOI: 10.1021/Pr400861M  0.36
2014 Menon R, Im H, Zhang EY, Wu SL, Chen R, Snyder M, Hancock WS, Omenn GS. Distinct splice variants and pathway enrichment in the cell-line models of aggressive human breast cancer subtypes. Journal of Proteome Research. 13: 212-27. PMID 24111759 DOI: 10.1021/Pr400773V  0.31
2013 Tousi F, Bones J, Hancock WS, Hincapie M. Differential chemical derivatization integrated with chromatographic separation for analysis of isomeric sialylated N-glycans: a nano-hydrophilic interaction liquid chromatography-MS platform. Analytical Chemistry. 85: 8421-8. PMID 23901877 DOI: 10.1021/Ac4018007  0.809
2013 Zhang EY, Cristofanilli M, Robertson F, Reuben JM, Mu Z, Beavis RC, Im H, Snyder M, Hofree M, Ideker T, Omenn GS, Fanayan S, Jeong SK, Paik YK, Zhang AF, ... ... Hancock WS, et al. Genome wide proteomics of ERBB2 and EGFR and other oncogenic pathways in inflammatory breast cancer. Journal of Proteome Research. 12: 2805-17. PMID 23647160 DOI: 10.1021/Pr4001527  0.322
2013 Fanayan S, Smith JT, Lee LY, Yan F, Snyder M, Hancock WS, Nice E. Proteogenomic analysis of human colon carcinoma cell lines LIM1215, LIM1899, and LIM2405. Journal of Proteome Research. 12: 1732-42. PMID 23458625 DOI: 10.1021/Pr3010869  0.625
2013 Wu SL, Taylor AD, Lu Q, Hanash SM, Im H, Snyder M, Hancock WS. Identification of potential glycan cancer markers with sialic acid attached to sialic acid and up-regulated fucosylated galactose structures in epidermal growth factor receptor secreted from A431 cell line. Molecular & Cellular Proteomics : McP. 12: 1239-49. PMID 23371026 DOI: 10.1074/Mcp.M112.024554  0.609
2013 Lee HJ, Jeong SK, Na K, Lee MJ, Lee SH, Lim JS, Cha HJ, Cho JY, Kwon JY, Kim H, Song SY, Yoo JS, Park YM, Kim H, Hancock WS, et al. Comprehensive genome-wide proteomic analysis of human placental tissue for the Chromosome-Centric Human Proteome Project. Journal of Proteome Research. 12: 2458-66. PMID 23362793 DOI: 10.1021/Pr301040G  0.394
2013 Kim KY, Joo HJ, Kwon HW, Kim H, Hancock WS, Paik YK. Development of a method to quantitate nematode pheromone for study of small-molecule metabolism in Caenorhabditis elegans. Analytical Chemistry. 85: 2681-8. PMID 23347231 DOI: 10.1021/Ac4001964  0.355
2013 Kwon KH, Kim JY, Kim SY, Min HK, Lee HJ, Ji IJ, Kang T, Park GW, An HJ, Lee B, Ravid R, Ferrer I, Chung CK, Paik YK, Hancock WS, et al. Chromosome 11-centric human proteome analysis of human brain hippocampus tissue. Journal of Proteome Research. 12: 97-105. PMID 23286719 DOI: 10.1021/Pr3008368  0.311
2013 Cao Z, Partyka K, McDonald M, Brouhard E, Hincapie M, Brand RE, Hancock WS, Haab BB. Modulation of glycan detection on specific glycoproteins by lectin multimerization. Analytical Chemistry. 85: 1689-98. PMID 23286506 DOI: 10.1021/Ac302826A  0.381
2013 Liu S, Im H, Bairoch A, Cristofanilli M, Chen R, Deutsch EW, Dalton S, Fenyo D, Fanayan S, Gates C, Gaudet P, Hincapie M, Hanash S, Kim H, Jeong SK, ... ... Hancock WS, et al. A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17. Journal of Proteome Research. 12: 45-57. PMID 23259914 DOI: 10.1021/Pr300985J  0.624
2013 Jeong SK, Lee HJ, Na K, Cho JY, Lee MJ, Kwon JY, Kim H, Park YM, Yoo JS, Hancock WS, Paik YK. GenomewidePDB, a proteomic database exploring the comprehensive protein parts list and transcriptome landscape in human chromosomes. Journal of Proteome Research. 12: 106-11. PMID 23252913 DOI: 10.1021/Pr3009447  0.363
2013 Fanayan S, Smith JT, Sethi MK, Cantor D, Goode R, Simpson RJ, Baker MS, Hancock WS, Nice E. Chromosome 7-centric analysis of proteomics data from a panel of human colon carcinoma cell lines. Journal of Proteome Research. 12: 89-96. PMID 23244008 DOI: 10.1021/Pr300906Y  0.357
2013 Goode RJ, Yu S, Kannan A, Christiansen JH, Beitz A, Hancock WS, Nice E, Smith AI. The proteome browser web portal. Journal of Proteome Research. 12: 172-8. PMID 23215242 DOI: 10.1021/Pr3010056  0.345
2013 Dorai H, Liu S, Yao X, Wang Y, Tekindemir U, Lewis MJ, Wu SL, Hancock W. Proteomic analysis of bioreactor cultures of an antibody expressing CHOGS cell line that promotes high productivity Journal of Proteomics and Bioinformatics. 6: 99-108. DOI: 10.4172/Jpb.1000268  0.349
2012 Lee LY, Hincapie M, Packer N, Baker MS, Hancock WS, Fanayan S. An optimized approach for enrichment of glycoproteins from cell culture lysates using native multi-lectin affinity chromatography. Journal of Separation Science. 35: 2445-52. PMID 22997032 DOI: 10.1002/Jssc.201200049  0.404
2012 Tousi F, Bones J, Iliopoulos O, Hancock WS, Hincapie M. Multidimensional liquid chromatography platform for profiling alterations of clusterin N-glycosylation in the plasma of patients with renal cell carcinoma. Journal of Chromatography. A. 1256: 121-8. PMID 22885037 DOI: 10.1016/J.Chroma.2012.07.066  0.802
2012 Tep S, Hincapie M, Hancock WS. The characterization and quantitation of glycomic changes in CHO cells during a bioreactor campaign. Biotechnology and Bioengineering. 109: 3007-17. PMID 22752974 DOI: 10.1002/Bit.24590  0.793
2012 Fanayan S, Hincapie M, Hancock WS. Using lectins to harvest the plasma/serum glycoproteome. Electrophoresis. 33: 1746-54. PMID 22740463 DOI: 10.1002/Elps.201100567  0.463
2012 Carlage T, Kshirsagar R, Zang L, Janakiraman V, Hincapie M, Lyubarskaya Y, Weiskopf A, Hancock WS. Analysis of dynamic changes in the proteome of a Bcl-XL overexpressing Chinese hamster ovary cell culture during exponential and stationary phases. Biotechnology Progress. 28: 814-23. PMID 22556165 DOI: 10.1002/Btpr.1534  0.792
2012 Paik YK, Omenn GS, Uhlen M, Hanash S, Marko-Varga G, Aebersold R, Bairoch A, Yamamoto T, Legrain P, Lee HJ, Na K, Jeong SK, He F, Binz PA, Nishimura T, ... ... Hancock WS, et al. Standard guidelines for the chromosome-centric human proteome project. Journal of Proteome Research. 11: 2005-13. PMID 22443261 DOI: 10.1021/Pr200824A  0.332
2012 Paik YK, Jeong SK, Omenn GS, Uhlen M, Hanash S, Cho SY, Lee HJ, Na K, Choi EY, Yan F, Zhang F, Zhang Y, Snyder M, Cheng Y, Chen R, ... ... Hancock WS, et al. The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome. Nature Biotechnology. 30: 221-3. PMID 22398612 DOI: 10.1038/Nbt.2152  0.565
2012 Lu Q, Padler-Karavani V, Yu H, Chen X, Wu SL, Varki A, Hancock WS. LC-MS analysis of polyclonal human anti-Neu5Gc xeno-autoantibodies immunoglobulin G Subclass and partial sequence using multistep intravenous immunoglobulin affinity purification and multienzymatic digestion. Analytical Chemistry. 84: 2761-8. PMID 22390546 DOI: 10.1021/Ac2030893  0.629
2012 Tep S, Hincapie M, Hancock WS. A general approach for the purification and quantitative glycomic analysis of human plasma. Analytical and Bioanalytical Chemistry. 402: 2687-700. PMID 22274286 DOI: 10.1007/S00216-012-5712-5  0.803
2012 Tep S, Hincapie M, Hancock WS. A MALDI-TOF MS method for the simultaneous and quantitative analysis of neutral and sialylated glycans of CHO-expressed glycoproteins. Carbohydrate Research. 347: 121-9. PMID 22138464 DOI: 10.1016/J.Carres.2011.10.005  0.79
2012 Rafalko A, Dai S, Hancock WS, Karger BL, Hincapie M. Development of a Chip/Chip/SRM platform using digital chip isoelectric focusing and LC-Chip mass spectrometry for enrichment and quantitation of low abundance protein biomarkers in human plasma. Journal of Proteome Research. 11: 808-17. PMID 22098410 DOI: 10.1021/Pr2006704  0.814
2012 Udiavar S, Apffel A, Chakel J, Swedberg S, Hancock WS, Pungor E. The use of multidimensional liquid-phase separations and mass spectrometry for the detailed characterization of posttranslational modifications in glycoproteins. Analytical Chemistry. 70: 3572-8. PMID 21644704 DOI: 10.1021/ac980405q  0.304
2012 Apffel A, Chakel JA, Fischer S, Lichtenwalter K, Hancock WS. Analysis of Oligonucleotides by HPLC-Electrospray Ionization Mass Spectrometry. Analytical Chemistry. 69: 1320-5. PMID 21639339 DOI: 10.1021/Ac960916H  0.391
2011 Tousi F, Hancock WS, Hincapie M. Technologies and strategies for glycoproteomics and glycomics and their application to clinical biomarker research. Analytical Methods : Advancing Methods and Applications. 3: 20-32. PMID 32938106 DOI: 10.1039/C0Ay00413H  0.793
2011 Legrain P, Aebersold R, Archakov A, Bairoch A, Bala K, Beretta L, Bergeron J, Borchers CH, Corthals GL, Costello CE, Deutsch EW, Domon B, Hancock W, He F, Hochstrasser D, et al. The human proteome project: current state and future direction. Molecular & Cellular Proteomics : McP. 10: M111.009993. PMID 21742803 DOI: 10.1074/Mcp.M111.009993  0.365
2011 Zeng Z, Hincapie M, Pitteri SJ, Hanash S, Schalkwijk J, Hogan JM, Wang H, Hancock WS. A proteomics platform combining depletion, multi-lectin affinity chromatography (M-LAC), and isoelectric focusing to study the breast cancer proteome. Analytical Chemistry. 83: 4845-54. PMID 21513341 DOI: 10.1021/Ac2002802  0.471
2011 Wang Y, Lu Q, Wu SL, Karger BL, Hancock WS. Characterization and comparison of disulfide linkages and scrambling patterns in therapeutic monoclonal antibodies: using LC-MS with electron transfer dissociation. Analytical Chemistry. 83: 3133-40. PMID 21428412 DOI: 10.1021/Ac200128D  0.605
2011 Dorai H, Santiago A, Campbell M, Tang QM, Lewis MJ, Wang Y, Lu QZ, Wu SL, Hancock W. Characterization of the proteases involved in the N-terminal clipping of glucagon-like-peptide-1-antibody fusion proteins. Biotechnology Progress. 27: 220-31. PMID 21312369 DOI: 10.1002/Btpr.537  0.632
2011 Murugesan N, Macdonald JA, Lu Q, Wu SL, Hancock WS, Pachter JS. Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics. Methods in Molecular Biology (Clifton, N.J.). 686: 297-311. PMID 21082378 DOI: 10.1007/978-1-60761-938-3_14  0.638
2011 Tousi F, Hancock WS, Hincapie M. Technologies and strategies for glycoproteomics and glycomics and their application to clinical biomarker research Analytical Methods. 3: 20-32. DOI: 10.1039/c0ay00413h  0.795
2010 Rafalko A, Iliopoulos O, Fusaro VA, Hancock W, Hincapie M. Immunoaffinity enrichment and liquid chromatography-selected reaction monitoring mass spectrometry for quantitation of carbonic anhydrase 12 in cultured renal carcinoma cells. Analytical Chemistry. 82: 8998-9005. PMID 20936840 DOI: 10.1021/Ac101981T  0.814
2010 Mischak H, Allmaier G, Apweiler R, Attwood T, Baumann M, Benigni A, Bennett SE, Bischoff R, Bongcam-Rudloff E, Capasso G, Coon JJ, D'Haese P, Dominiczak AF, Dakna M, Dihazi H, ... ... Hancock WS, et al. Recommendations for biomarker identification and qualification in clinical proteomics. Science Translational Medicine. 2: 46ps42. PMID 20739680 DOI: 10.1126/Scitranslmed.3001249  0.334
2010 Lee A, Nakano M, Hincapie M, Kolarich D, Baker MS, Hancock WS, Packer NH. The lectin riddle: Glycoproteins fractionated from complex mixtures have similar glycomic profiles Omics a Journal of Integrative Biology. 14: 487-499. PMID 20726804 DOI: 10.1089/Omi.2010.0075  0.373
2010 Jiang H, Wu SL, Karger BL, Hancock WS. Characterization of the glycosylation occupancy and the active site in the follow-on protein therapeutic: TNK-tissue plasminogen activator. Analytical Chemistry. 82: 6154-62. PMID 20552988 DOI: 10.1021/Ac100956X  0.515
2010 Wu SL, Jiang H, Hancock WS, Karger BL. Identification of the unpaired cysteine status and complete mapping of the 17 disulfides of recombinant tissue plasminogen activator using LC-MS with electron transfer dissociation/collision induced dissociation. Analytical Chemistry. 82: 5296-303. PMID 20481521 DOI: 10.1021/Ac100766R  0.541
2010 Kullolli M, Hancock WS, Hincapie M. Automated platform for fractionation of human plasma glycoproteome in clinical proteomics. Analytical Chemistry. 82: 115-20. PMID 19957969 DOI: 10.1021/Ac9013308  0.808
2010 Zeng Z, Hincapie M, Haab BB, Hanash S, Pitteri SJ, Kluck S, Hogan JM, Kennedy J, Hancock WS. The development of an integrated platform to identify breast cancer glycoproteome changes in human serum. Journal of Chromatography. A. 1217: 3307-15. PMID 19782370 DOI: 10.1016/J.Chroma.2009.09.029  0.428
2009 Lu Q, Zheng X, McIntosh T, Davis H, Nemeth JF, Pendley C, Wu SL, Hancock WS. Development of different analysis platforms with LC-MS for pharmacokinetic studies of protein drugs. Analytical Chemistry. 81: 8715-23. PMID 19788250 DOI: 10.1021/Ac901991X  0.626
2009 Akella LM, Rejtar T, Orazine C, Hincapie M, Hancock WS. CLUE-TIPS, clustering methods for pattern analysis of LC-MS data. Journal of Proteome Research. 8: 4732-42. PMID 19725534 DOI: 10.1021/Pr900427Q  0.794
2009 Carlage T, Hincapie M, Zang L, Lyubarskaya Y, Madden H, Mhatre R, Hancock WS. Proteomic profiling of a high-producing Chinese hamster ovary cell culture. Analytical Chemistry. 81: 7357-62. PMID 19663468 DOI: 10.1021/Ac900792Z  0.784
2009 Taylor AD, Hancock WS, Hincapie M, Taniguchi N, Hanash SM. Towards an integrated proteomic and glycomic approach to finding cancer biomarkers. Genome Medicine. 1: 57. PMID 19519948 DOI: 10.1186/Gm57  0.42
2009 Jiang H, Wu SL, Karger BL, Hancock WS. Mass spectrometric analysis of innovator, counterfeit, and follow-on recombinant human growth hormone. Biotechnology Progress. 25: 207-18. PMID 19224592 DOI: 10.1002/Btpr.72  0.557
2009 Zheng X, Wu SL, Hincapie M, Hancock WS. Study of the human plasma proteome of rheumatoid arthritis. Journal of Chromatography. A. 1216: 3538-45. PMID 19215933 DOI: 10.1016/J.Chroma.2009.01.063  0.447
2009 Wu SL, Jiang H, Lu Q, Dai S, Hancock WS, Karger BL. Mass spectrometric determination of disulfide linkages in recombinant therapeutic proteins using online LC-MS with electron-transfer dissociation. Analytical Chemistry. 81: 112-22. PMID 19117448 DOI: 10.1021/Ac801560K  0.71
2008 Plavina T, Hincapie M, Wakshull E, Subramanyam M, Hancock WS. Increased plasma concentrations of cytoskeletal and Ca2+-binding proteins and their peptides in psoriasis patients. Clinical Chemistry. 54: 1805-14. PMID 18801941 DOI: 10.1373/Clinchem.2008.103770  0.339
2008 Kullolli M, Hancock WS, Hincapie M. Preparation of a high-performance multi-lectin affinity chromatography (HP-M-LAC) adsorbent for the analysis of human plasma glycoproteins. Journal of Separation Science. 31: 2733-9. PMID 18693314 DOI: 10.1002/Jssc.200800233  0.794
2008 Lu Q, Murugesan N, Macdonald JA, Wu SL, Pachter JS, Hancock WS. Analysis of mouse brain microvascular endothelium using immuno-laser capture microdissection coupled to a hybrid linear ion trap with Fourier transform-mass spectrometry proteomics platform Electrophoresis. 29: 2689-2695. PMID 18481836 DOI: 10.1002/Elps.200700936  0.666
2008 Orazine CI, Hincapie M, Hancock WS, Hattersley M, Hanke JH. A proteomic analysis of the plasma glycoproteins of a MCF-7 mouse xenograft: a model system for the detection of tumor markers. Journal of Proteome Research. 7: 1542-54. PMID 18336003 DOI: 10.1021/Pr7008516  0.782
2008 Dayarathna MK, Hancock WS, Hincapie M. A two step fractionation approach for plasma proteomics using immunodepletion of abundant proteins and multi-lectin affinity chromatography: Application to the analysis of obesity, diabetes, and hypertension diseases. Journal of Separation Science. 31: 1156-66. PMID 18306431 DOI: 10.1002/Jssc.200700271  0.363
2008 Ralin DW, Dultz SC, Silver JE, Travis JC, Kullolli M, Hancock WS, Hincapie M. Kinetic analysis of glycoprotein-lectin interactions by label-free internal reflection ellipsometry Clinical Proteomics. 4: 37-46. DOI: 10.1007/S12014-008-9007-Y  0.783
2007 Csanky E, Olivova P, Rajnavolgyi E, Hempel W, Tardieu N, Katalin ET, Jullien A, Malderez-Bloes C, Kuras M, Duval MX, Nagy L, Scholtz B, Hancock W, Karger B, Guttman A, et al. Monoclonal antibody proteomics: Discovery and prevalidation of chronic obstructive pulmonary disease biomarkers in a single step Electrophoresis. 28: 4401-4406. PMID 18041035 DOI: 10.1002/Elps.200700256  0.349
2007 Gu Y, Wu SL, Meyer JL, Hancock WS, Burg LJ, Linder J, Hanlon DW, Karger BL. Proteomic analysis of high-grade dysplastic cervical cells obtained from ThinPrep slides using laser capture microdissection and mass spectrometry. Journal of Proteome Research. 6: 4256-68. PMID 17902640 DOI: 10.1021/Pr070319J  0.451
2007 Plavina T, Wakshull E, Hancock WS, Hincapie M. Combination of abundant protein depletion and multi-lectin affinity chromatography (M-LAC) for plasma protein biomarker discovery. Journal of Proteome Research. 6: 662-71. PMID 17269723 DOI: 10.1021/Pr060413K  0.361
2006 Zheng X, Baker H, Hancock WS, Fawaz F, McCaman M, Pungor E. Proteomic analysis for the assessment of different lots of fetal bovine serum as a raw material for cell culture. Part IV. Application of proteomics to the manufacture of biological drugs. Biotechnology Progress. 22: 1294-300. PMID 17022666 DOI: 10.1021/Bp060121O  0.339
2006 Wang Y, Dai Z, Sadee W, Hancock WS. A pharmacoproteomics study of the cancer cell line EKVX using capillary-LC/MS/MS. Molecular Pharmaceutics. 3: 566-78. PMID 17009856 DOI: 10.1021/Mp060002B  0.412
2006 Zheng X, Wu SL, Hancock WS. Glycation of interferon-beta-1b and human serum albumin in a lyophilized glucose formulation. Part III: application of proteomic analysis to the manufacture of biological drugs. International Journal of Pharmaceutics. 322: 136-45. PMID 16920285 DOI: 10.1016/J.Ijpharm.2006.06.038  0.335
2006 Yang Z, Harris LE, Palmer-Toy DE, Hancock WS. Multilectin affinity chromatography for characterization of multiple glycoprotein biomarker candidates in serum from breast cancer patients. Clinical Chemistry. 52: 1897-905. PMID 16916992 DOI: 10.1373/Clinchem.2005.065862  0.302
2006 Wang Y, Wu SL, Hancock WS. Monitoring of glycoprotein products in cell culture lysates using lectin affinity chromatography and capillary HPLC coupled to electrospray linear ion trap-Fourier transform mass spectrometry (LTQ/FTMS). Biotechnology Progress. 22: 873-80. PMID 16739974 DOI: 10.1021/Bp060005L  0.432
2006 Zheng X, Baker H, Hancock WS. Analysis of the low molecular weight serum peptidome using ultrafiltration and a hybrid ion trap-Fourier transform mass spectrometer. Journal of Chromatography. A. 1120: 173-84. PMID 16527286 DOI: 10.1016/J.Chroma.2006.01.098  0.398
2006 Plymoth A, Yang Z, Löfdahl CG, Ekberg-Jansson A, Dahlbäck M, Fehniger TE, Marko-Varga G, Hancock WS. Rapid proteome analysis of bronchoalveolar lavage samples of lifelong smokers and never-smokers by micro-scale liquid chromatography and mass spectrometry. Clinical Chemistry. 52: 671-9. PMID 16497942 DOI: 10.1373/Clinchem.2005.060715  0.313
2006 Wang Y, Wu SL, Hancock WS. Approaches to the study of N-linked glycoproteins in human plasma using lectin affinity chromatography and nano-HPLC coupled to electrospray linear ion trap--Fourier transform mass spectrometry. Glycobiology. 16: 514-23. PMID 16497783 DOI: 10.1093/Glycob/Cwj091  0.422
2005 Wang Y, Wu SL, Hancock WS, Trala R, Kessler M, Taylor AH, Patel PS, Aon JC. Proteomic profiling of Escherichia coli proteins under high cell density fed-batch cultivation with overexpression of phosphogluconolactonase. Biotechnology Progress. 21: 1401-11. PMID 16209543 DOI: 10.1021/Bp050048M  0.414
2005 Ping P, Vondriska TM, Creighton CJ, Gandhi TK, Yang Z, Menon R, Kwon MS, Cho SY, Drwal G, Kellmann M, Peri S, Suresh S, Gronborg M, Molina H, Chaerkady R, ... ... Hancock WS, et al. A functional annotation of subproteomes in human plasma. Proteomics. 5: 3506-19. PMID 16104058 DOI: 10.1002/Pmic.200500140  0.411
2005 Omenn GS, States DJ, Adamski M, Blackwell TW, Menon R, Hermjakob H, Apweiler R, Haab BB, Simpson RJ, Eddes JS, Kapp EA, Moritz RL, Chan DW, Rai AJ, Admon A, ... ... Hancock WS, et al. Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database. Proteomics. 5: 3226-45. PMID 16104056 DOI: 10.1002/Pmic.200500358  0.461
2005 Wu SL, Kim J, Hancock WS, Karger B. Extended Range Proteomic Analysis (ERPA): a new and sensitive LC-MS platform for high sequence coverage of complex proteins with extensive post-translational modifications-comprehensive analysis of beta-casein and epidermal growth factor receptor (EGFR). Journal of Proteome Research. 4: 1155-70. PMID 16083266 DOI: 10.1021/Pr050113N  0.342
2005 Yang Z, Hancock WS, Chew TR, Bonilla L. A study of glycoproteins in human serum and plasma reference standards (HUPO) using multilectin affinity chromatography coupled with RPLC-MS/MS. Proteomics. 5: 3353-66. PMID 16052617 DOI: 10.1002/Pmic.200401190  0.396
2005 Yang Z, Hancock WS. Monitoring glycosylation pattern changes of glycoproteins using multi-lectin affinity chromatography. Journal of Chromatography. A. 1070: 57-64. PMID 15861788 DOI: 10.1016/J.Chroma.2005.02.034  0.414
2005 Baker H, Patel V, Molinolo AA, Shillitoe EJ, Ensley JF, Yoo GH, Meneses-García A, Myers JN, El-Naggar AK, Gutkind JS, Hancock WS. Proteome-wide analysis of head and neck squamous cell carcinomas using laser-capture microdissection and tandem mass spectrometry. Oral Oncology. 41: 183-99. PMID 15695121 DOI: 10.1016/J.Oraloncology.2004.08.009  0.401
2005 Hancock WS. Hints of the Post-Proteome Era Journal of Proteome Research. 4: 657-657. DOI: 10.1021/Pr050509Z  0.322
2005 Hancock WS. Toward a Common Proteomics Platform Journal of Proteome Research. 4: 213-213. DOI: 10.1021/Pr050502H  0.346
2004 Wang Y, Hancock WS, Weber G, Eckerskorn C, Palmer-Toy D. Free flow electrophoresis coupled with liquid chromatography-mass spectrometry for a proteomic study of the human cell line (K562/CR3). Journal of Chromatography. A. 1053: 269-78. PMID 15543993 DOI: 10.1016/J.Chroma.2004.08.164  0.476
2004 Yang Z, Hancock WS. Approach to the comprehensive analysis of glycoproteins isolated from human serum using a multi-lectin affinity column. Journal of Chromatography. A. 1053: 79-88. PMID 15543974 DOI: 10.1016/J.Chroma.2004.08.150  0.405
2004 Wu SL, Jardine I, Hancock WS, Karger BL. A new and sensitive on-line liquid chromatography/mass spectrometric approach for top-down protein analysis: the comprehensive analysis of human growth hormone in an E. coli lysate using a hybrid linear ion trap/Fourier transform ion cyclotron resonance mass spectrometer. Rapid Communications in Mass Spectrometry : Rcm. 18: 2201-7. PMID 15384137 DOI: 10.1002/Rcm.1609  0.419
2004 Zang L, Palmer Toy D, Hancock WS, Sgroi DC, Karger BL. Proteomic analysis of ductal carcinoma of the breast using laser capture microdissection, LC-MS, and 16O/18O isotopic labeling. Journal of Proteome Research. 3: 604-12. PMID 15253443 DOI: 10.1021/Pr034131L  0.391
2003 Hancock WS. What is new in proteomics? Biomarkers. Journal of Proteome Research. 2: 457. PMID 14582641 DOI: 10.1021/Pr030737Y  0.304
2003 Wu SL, Choudhary G, Ramström M, Bergquist J, Hancock WS. Evaluation of shotgun sequencing for proteomic analysis of human plasma using HPLC coupled with either ion trap or Fourier transform mass spectrometry Journal of Proteome Research. 2: 383-393. PMID 12938928 DOI: 10.1021/Pr034015I  0.471
2003 Wu SL, Hancock WS, Goodrich GG, Kunitake ST. An approach to the proteomic analysis of a breast cancer cell line (SKBR-3). Proteomics. 3: 1037-46. PMID 12833528 DOI: 10.1002/Pmic.200300382  0.451
2003 Choudhary G, Wu SL, Shieh P, Hancock WS. Multiple enzymatic digestion for enhanced sequence coverage of proteins in complex proteomic mixtures using capillary LC with ion trap MS/MS. Journal of Proteome Research. 2: 59-67. PMID 12643544 DOI: 10.1021/Pr025557N  0.43
2003 Hancock WS. The Challenge of High-Molecular-Weight Protein Characterization Journal of Proteome Research. 2: 345-345. DOI: 10.1021/Pr030734L  0.301
2002 Wu SL, Amato H, Biringer R, Choudhary G, Shieh P, Hancock WS. Targeted proteomics of low-level proteins in human plasma by LC/MSn: using human growth hormone as a model system. Journal of Proteome Research. 1: 459-65. PMID 12645918 DOI: 10.1021/Pr025537L  0.47
2002 Hancock WS. Proteomics versus immunoassays. Journal of Proteome Research. 1: 393. PMID 12645910 DOI: 10.1021/Pr020340E  0.375
2002 Hancock WS, Wu SL, Stanley RR, Gombocz EA. Publishing large proteome datasets: scientific policy meets emerging technologies. Trends in Biotechnology. 20: S39-44. PMID 12570159 DOI: 10.1016/S1471-1931(02)00205-7  0.394
2002 Hancock WS, Wu SL, Shieh P. The challenges of developing a sound proteomics strategy. Proteomics. 2: 352-9. PMID 12164694 DOI: 10.1002/1615-9861(200204)2:4<352::Aid-Prot352>3.0.Co;2-U  0.44
2001 McCaman MT, Murakami P, Pungor E, Hahnenberger KM, Hancock WS. Analysis of recombinant adenoviruses using an integrated microfluidic chip-based system. Analytical Biochemistry. 291: 262-8. PMID 11401300 DOI: 10.1006/Abio.2001.5043  0.317
2001 Lichtenwalter KG, Apffel A, Bai J, Chakel JA, Dai Y, Hahnenberger KM, Li L, Hancock WS. Approaches to functional genomics: potential of matrix-assisted laser desorption ionization--time of flight mass spectrometry combined with separation methods for the analysis of DNA in biological samples. Journal of Chromatography. B, Biomedical Sciences and Applications. 745: 231-41. PMID 10997718 DOI: 10.1016/S0378-4347(00)00131-6  0.369
2000 Choudhary G, Apffel A, Yin H, Hancock W. Use of on-line mass spectrometric detection in capillary electrochromatography Journal of Chromatography A. 887: 85-101. PMID 10961305 DOI: 10.1016/S0021-9673(00)00530-6  0.367
1999 Hancock W, Apffel A, Chakel J, Hahnenberger K, Choudhary G, Traina JA, Pungor E. Integrated genomic/proteomic analysis Analytical Chemistry. 71. PMID 10565269 DOI: 10.1021/Ac9907641  0.316
1999 Choudhary G, Hancock W, Witt K, Rozing G, Torres-Duarte A, Wainer I. Integrated approach to the multidimensional analysis of complex biological samples by microseparation techniques: Analysis of glycoprotein factor associated with cancer cachexia Journal of Chromatography A. 857: 183-192. PMID 10536837 DOI: 10.1016/S0021-9673(99)00783-9  0.372
1999 Lehmberg E, Traina JA, Chakel JA, Chang RJ, Parkman M, McCaman MT, Murakami PK, Lahidji V, Nelson JW, Hancock WS, Nestaas E, Pungor E. Reversed-phase high-performance liquid chromatographic assay for the adenovirus type 5 proteome Journal of Chromatography B: Biomedical Sciences and Applications. 732: 411-423. PMID 10517364 DOI: 10.1016/S0378-4347(99)00316-3  0.402
1999 Apffel A, Yin H, Hancock WS, McManigill D, Frenz J, Wu SL. Effect of electric field on liquid chromatographic separation of peptide digests. Combining capillary separation techniques. Journal of Chromatography. A. 832: 149-63. PMID 10070770 DOI: 10.1016/S0021-9673(98)00957-1  0.795
1999 Choudhary G, Chakel J, Hancock W, Torres-Duarte A, McMahon G, Wainer I. Investigation of the potential of capillary electrophoresis with off- line matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for clinical analysis: Examination of a glycoprotein factor associated with cancer cachexia Analytical Chemistry. 71: 855-859. PMID 10051848 DOI: 10.1021/Ac980633K  0.394
1999 Grimm R, Grasser KD, Kubach J, Hancock WS. A rapid and sensitive procedure for the micro-purification and subsequent characterization of peptides and protein samples by N-terminal sequencing and matrix assisted laser desorption ionization time of flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 18: 545-54. PMID 9919954 DOI: 10.1016/S0731-7085(98)00208-8  0.473
1999 Fleming CM, Kowalski BR, Apffel A, Hancock WS. Windowed mass selection method: a new data processing algorithm for liquid chromatography–mass spectrometry data Journal of Chromatography A. 849: 71-85. DOI: 10.1016/S0021-9673(99)00553-1  0.337
1997 Chakel JA, Pungor E, Hancock WS, Swedberg SA. Analysis of recombinant DNA-derived glycoproteins via high-performance capillary electrophoresis coupled with off-line matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Journal of Chromatography. B, Biomedical Sciences and Applications. 689: 215-20. PMID 9061496 DOI: 10.1016/S0378-4347(96)00373-8  0.409
1997 Apffel A, Chakel JA, Hancock WS, Souders C, M'Timkulu T, Pungor E. Application of multidimensional affinity high-performance liquid chromatography and electrospray ionization liquid chromatography-mass spectrometry to the characterization of glycosylation in single-chain plasminogen activator. Initial results. Journal of Chromatography. A. 750: 35-42. PMID 8938380 DOI: 10.1016/0021-9673(96)00528-6  0.408
1997 Apffel A, Chakel JA, Fischer S, Lichtenwalter K, Hancock WS. New procedure for the use of high-performance liquid chromatography–electrospray ionization mass spectrometry for the analysis of nucleotides and oligonucleotides Journal of Chromatography A. 777: 3-21. DOI: 10.1016/S0021-9673(97)00256-2  0.401
1996 Hancock WS, Apffel A, Chakel J, Souders C, M'Timkulu T, Pungor E, Guzzetta AW. Reversed-phase peptide mapping of glycoproteins using liquid chromatography/electrospray ionization-mass spectrometry. Methods in Enzymology. 271: 403-27. PMID 8782563 DOI: 10.1016/S0076-6879(96)71019-4  0.424
1996 Apffel A, Chakel JA, Hancock WS, Souders C, M'Timkulu T, Pungor E. Application of high-performance liquid chromatograph-electrospray ionization mass spectrometry and matrix-assisted laser-desorption ionization time-of-flight mass spectrometry in combination with selective enzymatic modifications in the characterization of glycosylation patterns in single-chain plasminogen activator. Journal of Chromatography. A. 732: 27-42. PMID 8646333 DOI: 10.1016/0021-9673(95)01231-1  0.416
1996 Apffel A, Chakel J, Udiavar S, Hancock WS, Souders C, Pungor E. Application of capillary electrophoresis, high-performance liquid chromatography, on-line electrospray mass spectrometry and matrix-assisted laser desorption ionization--time of flight mass spectrometry to the characterization of single-chain plasminogen activator. Journal of Chromatography. A. 717: 41-60. PMID 8520684 DOI: 10.1016/0021-9673(95)00603-0  0.429
1995 Battersby JE, Mukku VR, Clark RG, Hancock WS. Affinity purification and microcharacterization of recombinant DNA-derived human growth hormone isolated from an in vivo model. Analytical Chemistry. 67: 447-55. PMID 7856886 DOI: 10.1021/Ac00098A600  0.374
1995 Battersby JE, Guzzetta AW, Hancock WS. Application of capillary high-performance liquid chromatography to biotechnology, with reference to the analysis of recombinant DNA-derived human growth hormone. Journal of Chromatography. B, Biomedical Applications. 662: 335-42. PMID 7719487 DOI: 10.1016/0378-4347(94)00312-2  0.399
1994 Lewis DA, Guzzetta AW, Hancock WS, Costello M. Characterization of humanized anti-TAC, an antibody directed against the interleukin 2 receptor, using electrospray ionization mass spectrometry by direct infusion, LC/MS, and MS/MS. Analytical Chemistry. 66: 585-95. PMID 8154587 DOI: 10.1021/Ac00077A003  0.407
1994 Chloupek RC, Hancock WS, Marchylo BA, Kirkland JJ, Boyes BE, Snyder LR. Temperature as a variable in reversed-phase high-performance liquid chromatographic separations of peptide and protein samples. II. Selectivity effects observed in the separation of several peptide and protein mixtures. Journal of Chromatography. A. 686: 45-59. PMID 7849983 DOI: 10.1016/S0021-9673(94)89009-9  0.366
1994 Hancock WS, Chloupek RC, Kirkland JJ, Snyder LR. Temperature as a variable in reversed-phase high-performance liquid chromatographic separations of peptide and protein samples. I. Optimizing the separation of a growth hormone tryptic digest. Journal of Chromatography. A. 686: 31-43. PMID 7849982 DOI: 10.1016/0021-9673(94)00077-8  0.383
1994 Anicetti V, Hancock WS. Analytical Considerations in the Development of Protein Purification Processes Bioprocess Technology. 18: 11-36. DOI: 10.1201/9780203741733-2  0.348
1993 Maschke HE, Frenz J, Belenkii A, Karger BL, Hancock WS. Ultrasensitive plasmid mapping by high performance capillary electrophoresis Electrophoresis. 14: 509-514. PMID 8354236 DOI: 10.1002/Elps.1150140178  0.78
1993 Guzzetta AW, Basa LJ, Hancock WS, Keyt BA, Bennett WF. Identification of carbohydrate structures in glycoprotein peptide maps by the use of LC/MS with selected ion extraction with special reference to tissue plasminogen activator and a glycosylation variant produced by site directed mutagenesis. Analytical Chemistry. 65: 2953-62. PMID 8256861 DOI: 10.1021/Ac00069A004  0.421
1992 Frenz J, Quan CP, Hancock WS, Bourell J. Characterization of a tryptic digest by high-performance displacement chromatography and mass spectrometry. Journal of Chromatography. 557: 289-305. PMID 1744202 DOI: 10.1016/S0021-9673(01)87139-9  0.811
1992 Chloupek RC, Hancock WS, Snyder LR. Computer simulation as a tool for the rapid optimization of the high-performance liquid chromatographic separation of a tryptic digest of human growth hormone. Journal of Chromatography. 594: 65-73. PMID 1587930 DOI: 10.1016/0021-9673(92)80313-J  0.36
1992 Oroszlan P, Wicar S, Teshima G, Wu SL, Hancock WS, Karger BL. Conformational effects in the reversed-phase chromatographic behavior of recombinant human growth hormone (rhGH) and N-methionyl recombinant human growth hormone (Met-hGH) Analytical Chemistry. 64: 1623-1631. PMID 1503227 DOI: 10.1021/Ac00038A021  0.337
1991 Ling V, Guzzetta AW, Canova-Davis E, Stults JT, Hancock WS, Covey TR, Shushan BI. Characterization of the tryptic map of recombinant DNA derived tissue plasminogen activator by high-performance liquid chromatography-electrospray ionization mass spectrometry. Analytical Chemistry. 63: 2909-15. PMID 1789452 DOI: 10.1021/Ac00024A020  0.396
1991 Frenz J, Hancock WS. High performance capillary electrophoresis. Trends in Biotechnology. 9: 243-50. PMID 1367350 DOI: 10.1016/0167-7799(91)90078-V  0.801
1990 Wu SL, Hancock WS, Pavlu B, Gellerfors P. Application of high-performance hydrophobic-interaction chromatography to the characterization of recombinant DNA-derived human growth hormone. Journal of Chromatography. 500: 595-606. PMID 2329152 DOI: 10.1016/S0021-9673(00)96094-1  0.39
1990 Sievert HJ, Wu SL, Chloupek R, Hancock WS. Automated evaluation of tryptic digest from recombinant human growth hormone using ultraviolet spectra and numeric peak information. Journal of Chromatography. 499: 221-34. PMID 2324209 DOI: 10.1016/S0021-9673(00)96975-9  0.327
1990 Frenz J, Bourell J, Hancock WS. High-performance displacement chromatography-mass spectrometry of tryptic peptides of recombinant human growth hormone. Journal of Chromatography. 512: 299-314. PMID 2229231 DOI: 10.1016/S0021-9673(01)89497-8  0.814
1990 Canova-Davis E, Baldonado IP, Moore JA, Rudman CG, Bennett WF, Hancock WS. Properties of a cleaved two-chain form of recombinant human growth hormone. International Journal of Peptide and Protein Research. 35: 17-24. PMID 2182557 DOI: 10.1111/J.1399-3011.1990.Tb00716.X  0.347
1989 Frenz J, Wu SL, Hancock WS. Characterization of human growth hormone by capillary electrophoresis Journal of Chromatography A. 480: 379-391. PMID 2592489 DOI: 10.1016/S0021-9673(01)84307-7  0.811
1989 Chloupek RC, Harris RJ, Leonard CK, Keck RG, Keyt BA, Spellman MW, Jones AJ, Hancock WS. Study of the primary structure of recombinant tissue plasminogen activator by reversed-phase high-performance liquid chromatographic tryptic mapping. Journal of Chromatography. 463: 375-96. PMID 2496137 DOI: 10.1016/S0021-9673(01)84491-5  0.372
1987 Hancock WS, Prestidge RL. Chapter 6 Biochemical Applications of Preparative Liquid Chromatography Journal of Chromatography Library. 38: 203-233. DOI: 10.1016/S0301-4770(08)60369-3  0.402
1985 Harding DR, Hancock WS, Sparrow JT. Synthesis of peptide labelled with p-iodophenylalanine which corresponds to the first amphipathic region of apolipoprotein C-I. International Journal of Peptide and Protein Research. 26: 208-13. PMID 4066155 DOI: 10.1111/J.1399-3011.1985.Tb03198.X  0.36
1985 Poll D, Harding DR, Hancock WS, Nye ER, Janus ED, Hannan SF, Scott PJ. The use of reversed-phase high-performance liquid chromatography to analyse the cholesterol ester profiles present in lipoproteins of patients exhibiting hyperalphalipoproteinaemia or hypoalphalipoproteinaemia (Tangier disease). Journal of Chromatography. 343: 149-54. PMID 3934204 DOI: 10.1016/S0378-4347(00)84578-8  0.312
1985 Gunn PR, Sato F, Powell KF, Bellamy AR, Napier JR, Harding DR, Hancock WS, Siegman LJ, Both GW. Rotavirus neutralizing protein VP7: antigenic determinants investigated by sequence analysis and peptide synthesis. Journal of Virology. 54: 791-7. PMID 2582147 DOI: 10.1128/Jvi.54.3.791-797.1985  0.312
1985 Knighton DR, Harding DRK, Napier JR, Hancock WS. Purification of synthetic lipid associating peptides and the monitoring of the deformylation of Nin-formyltryptophan by reversed-phase high-performance liquid chromatography Journal of Chromatography A. 347: 237-248. DOI: 10.1016/S0021-9673(01)95489-5  0.348
1984 Christie DL, Birch NP, Aitken JF, Harding DR, Hancock WS. Antisera to synthetic peptide recognize high molecular weight enkephalin-containing proteins. Biochemical and Biophysical Research Communications. 120: 650-6. PMID 6203524 DOI: 10.1016/0006-291X(84)91305-6  0.33
1982 Hancock WS, Harding DR, Friedman Z. Rapid analysis of 3-methylhistidine in urine, plasma, muscle and amniotic fluid with a single high-performance liquid chromatographic system but with different ion-pairing reagents. Journal of Chromatography. 228: 273-8. PMID 7076749 DOI: 10.1016/S0378-4347(00)80440-5  0.328
1982 Knighton DR, Harding DRK, Napier JR, Hancock WS. Facile, semi-preparative, high-performance liquid chromatographicn separation of synthetic peptides using ammonium bicarbonate buffers Journal of Chromatography A. 249: 193-198. DOI: 10.1016/S0021-9673(00)80249-6  0.343
1981 Hearn MT, Harris EL, Bethell GS, Hancock WS, Ayers JA. Application of 1,1'-carbonyldiimidazole-activated matrices for the purification of proteins. III. The use of 1,1'-carbonyldiimidazole-activated agaroses in the biospecific affinity chromatographic isolation of serum antibodies. Journal of Chromatography. 218: 509-18. PMID 7320121 DOI: 10.1016/S0021-9673(00)82076-2  0.332
1981 Harding DR, Bishop CA, Tarttelin MF, Hancock WS. Use of perfluoroalkanoic acids as volatile ion pairing reagents in preparative HPLC. International Journal of Peptide and Protein Research. 18: 214-20. PMID 7309379 DOI: 10.1111/J.1399-3011.1981.Tb02060.X  0.325
1981 Hancock WS, Bishop CA, Gotto AM, Harding DR, Lamplugh SM, Sparrow JT. Separation of the apoprotein components of human very low density lipoproteins by ion-paired, reversed-phase high performance liquid chromatography. Lipids. 16: 250-9. PMID 7242277 DOI: 10.1007/Bf02535025  0.332
1981 Hancock WS, Sparrow JT. Use of mixed-mode, high-performance liquid chromatography for the separation of peptide and protein mixtures. Journal of Chromatography. 206: 71-82. PMID 7217282 DOI: 10.1016/S0021-9673(00)82606-0  0.37
1981 Hancock WS, Capra JD, Bradley WA, Sparrow JT. The use of reversed-phase high-performance liquid chromatography with radial compression for the analysis of peptide and protein mixtures. Journal of Chromatography. 206: 59-70. PMID 7217281 DOI: 10.1016/S0021-9673(00)82605-9  0.378
1981 Bishop CA, Meyer LJ, Harding DR, Hancock WS, Hearn MTW. The preparative separation of synthetic peptides on reversed-phase silica packed in radially compressed flexible-walled columns.+ Journal of Liquid Chromatography. 4: 661-680. DOI: 10.1080/01483918108059963  0.315
1981 Bishop CA, Hancock WS, Brennan SO, Carrell RW, Hearn MTW. High performance chromatography of amino acids, peptides and proteins xxiii-peptide mapping by hydrophilic ion-paired, reversed-phase high performance liquid chromatography for the characterisation of the tryptic digest of haemoglobin variants1 Journal of Liquid Chromatography. 4: 599-612. DOI: 10.1080/01483918108059958  0.366
1981 Bishop CA, Kitson TM, Harding DRK, Hancock WS. Investigation of the isolation of a mixed disulphide, diethylthiocarbamoyl 2-pyridyl disulphide by analytical and preparative high-performance liquid chromatography Journal of Chromatography A. 208: 141-147. DOI: 10.1016/S0021-9673(00)87977-7  0.33
1980 Friedman Z, Smith HW, Hancock WS. Rapid high-performance liquid chromatographic method for quantitation of 3-methylhistidine. Journal of Chromatography. 182: 414-8. PMID 7391184 DOI: 10.1016/S0378-4347(00)81492-9  0.333
1980 Hearn MT, Grego B, Hancock WS. High-performance liquid chromatography of amino acids, peptides and proteins. XX. Investigation of the effects of pH and ion-pair formation on the retention of peptides on chemically-bonded hydrocarbonaceous stationary phases. Journal of Chromatography. 185: 429-44. PMID 44715 DOI: 10.1016/S0021-9673(00)85619-8  0.302
1980 Hearn MT, Grego B, Bishop CA, Hancock WS. High-Speed Gel Permeation Chromatography of Human Thyroglobulin and Sheep Liver Aldehyde Dehydrogenase Journal of Liquid Chromatography. 3: 1549-1560. DOI: 10.1080/01483918008062795  0.31
1980 Bishop CA, Harding DRK, Meyer LJ, Hancock WS, Hearn MTW. High-performance liquid chromatography of amino acids, peptides and proteins. XXI. The application of preparative reversed-phase high-performance liquid chromatography for the purification of a synthetic underivatised peptide Journal of Chromatography A. 192: 222-227. DOI: 10.1016/S0021-9673(00)81858-0  0.378
1980 Hancock W. High-performance liquid chromatography Trends in Biochemical Sciences. 5: XVI-XVIII. DOI: 10.1016/0968-0004(80)90061-4  0.319
1979 Hearn MT, Bethell GS, Ayers JS, Hancock WS. Application of 1,1'-carbonyldiimidazole-activated agarose for the purification of proteins. II. The use of an activated matrix devoid of additional charged groups for the purification of thyroid proteins. Journal of Chromatography. 185: 463-70. PMID 546931 DOI: 10.1016/S0021-9673(00)85622-8  0.301
1979 Hancock WS, Bishop CA, Hearn MT. The analysis of nanogram levels of free amino acids by reverse-phase high-pressure liquid chromatography. Analytical Biochemistry. 92: 170-3. PMID 426276 DOI: 10.1016/0003-2697(79)90640-7  0.381
1979 Hearn MTW, Hancock WS, Hurrell JGR, Fleming RJ, Kemp B. The Analysis of Insulin-Related Peptides by Reversed-Phase High-Performance Liquid Chromatography Journal of Liquid Chromatography. 2: 919-933. DOI: 10.1080/01483917908060115  0.349
1979 Hearn MT, Bishop CA, Hancock WS, Harding DR, Reynolds GD. Application of Reversed Phase High Performance Liquid Chromatography in Solid Phase Peptide Synthesis Journal of Liquid Chromatography. 2: 1-21. DOI: 10.1080/01483917908060041  0.355
1979 Hearn MT, Hancock WS. Ion pair partition reversed phase HPLC Trends in Biochemical Sciences. 4: N58-N62. DOI: 10.1016/0968-0004(79)90254-8  0.322
1979 Hancock WS, Bishop CA, Battersby JE, Harding DRK, Hearn MTW. High-pressure liquid chromatography of peptides and proteins XI. The use of cationic reagents for the analysis of peptides by high-pressure liquid chromatography Journal of Chromatography A. 168: 377-384. DOI: 10.1016/0021-9673(79)80007-2  0.349
1978 Hancock WS, Bishop CA, Prestidge RL, Hearn MT. The use of high pressure liquid chromatography (hplc) for peptide mapping of proteins. IV. Analytical Biochemistry. 89: 203-12. PMID 707798 DOI: 10.1016/0003-2697(78)90742-X  0.429
1978 Hearn MT, Hancock WS, Bishop CA. High-pressure liquid chromatography of amino acids, peptides and proteins. V. Separation of thyroidal iodo-amino acids by hydrophilic ion-paired reversed-phase high-performance liquid chromatography. Journal of Chromatography. 157: 337-44. PMID 701445 DOI: 10.1016/S0021-9673(00)92351-3  0.344
1978 Hancock WS, Bishop CA, Prestidge RL, Harding DR, Hearn MT. Reversed-phase, high-pressure liquid chromatography of peptides and proteins with ion-pairing reagents. Science (New York, N.Y.). 200: 1168-70. PMID 206966 DOI: 10.1126/Science.206966  0.368
1978 Hancock WS, Bishop CA, Meyer LJ, Harding DRK, Hearn MTW. High-pressure liquid chromatography of peptides and proteins. VI. Rapid analysis of peptides by high-pressure liquid chromatography with hydrophobic ion-pairing of amino groups Journal of Chromatography A. 161: 291-298. DOI: 10.1016/S0021-9673(01)85239-0  0.349
1978 Hancock WS, Bishop CA, Prestidge RL, Harding DRK, Hearn MTW. High-pressure liquid chromatography of peptides and proteins. II. The use of phosphoric acid in the analysis of under-ivatised peptides by reversed-phase high-pressure liquid chromatography Journal of Chromatography A. 153: 391-398. DOI: 10.1016/S0021-9673(00)95499-2  0.354
1977 Hancock WS, Mander LN, Massy-Westropp RA. The rearrangement of some epoxy podocarpanoic acids Australian Journal of Chemistry. 30: 1093-1107. DOI: 10.1002/Chin.197736359  0.577
1976 Hancock WS, Battersby JE, Harding DR. The use of picric acid as a simple monitoring procedure for automated peptide synthesis. Analytical Biochemistry. 69: 497-503. PMID 1217716 DOI: 10.1016/0003-2697(75)90152-9  0.311
1976 Hancock WS, Bishop CA, Hearn MTW. High pressure liquid chromatography in the analysis of underivatised peptides using a sensitive and rapid procedure Febs Letters. 72: 139-142. PMID 1001457 DOI: 10.1016/0014-5793(76)80830-7  0.334
1973 Hancock WS, Mander LN, Massy-Westropp RA. A synthesis of rosenonolactone from podocarpic acid Journal of Organic Chemistry. 38: 4090-4091. DOI: 10.1021/Jo00987A040  0.577
1973 Hancock WS, Prescott DJ, Vagelos PR, Marshall GR. Solvation of the polymer matrix. Source of truncated and failure sequences in solid phase synthesis The Journal of Organic Chemistry. 38: 774-781. DOI: 10.1021/Jo00944A033  0.535
1973 HANCOCK WS, PRESCOTT DJ, VAGELOS PR, MARSHALL GR. ChemInform Abstract: SOLVATISIERUNG DER POLYMER-MATRIX, DIE QUELLE FUER VERSTUEMMELTE UND ABGELOESTE SEQUENZEN BEI DER FESTPHASEN-SYNTH. Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197322461  0.514
1971 Hancock WS, Prescott DJ, Nulty WL, Weintraub J, Vagelos PR, Marshall GR. The synthesis of a protein with acyl carrier protein activity [15] Journal of the American Chemical Society. 93: 1799-1800. PMID 4927590 DOI: 10.1021/Ja00736A048  0.592
1970 Greenspan MD, Birge CH, Powell G, Hancock WS, Vagelos PR. Enzyme specificity as a factor in regulation of fatty acid chain length in Escherichia coli. Science (New York, N.Y.). 170: 1203-4. PMID 4920654 DOI: 10.1126/Science.170.3963.1203  0.555
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