Ya-Wen Chen, Ph.D. - Related publications

Affiliations: 
2012 Molecular Medicine University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Molecular Biology, Cell Biology, Biochemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Byun WS, Kim S, Shin YH, Kim WK, Oh DC, Lee SK. Antitumor Activity of Ohmyungsamycin A through the Regulation of the Skp2-p27 Axis and MCM4 in Human Colorectal Cancer Cells. Journal of Natural Products. PMID 31894983 DOI: 10.1021/acs.jnatprod.9b00918   
2020 Yoon JH, Shin JW, Pham TH, Choi YJ, Ryu HW, Oh SR, Oh JW, Yoon DY. Methyl lucidone induces apoptosis and G/M phase arrest the PI3K/Akt/NF-κB pathway in ovarian cancer cells. Pharmaceutical Biology. 58: 51-59. PMID 31875458 DOI: 10.1080/13880209.2019.1701044   
2020 Li W, Ping Z, Xuemei G, Minglian L, Hongjuan M, Yi H, Zhongxiang Z. Naturally Occurring Sclareol Diterpene Augments the Chemosensitivity of Human Hela Cervical Cancer Cells by Inducing Mitochondrial Mediated Programmed Cell Death, S-Phase Cell Cycle Arrest and Targeting Mitogen-Activated Protein Kinase (MAPK)/Extracellular-Signal-Regulated Kinase (ERK) Signaling Pathway. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 26: e920248. PMID 31935210 DOI: 10.12659/MSM.920248   
2020 Yang K, Tang XJ, Xu FF, Liu JH, Tan YQ, Gao L, Sun Q, Ding X, Liu BH, Chen QX. PI3K/mTORC1/2 inhibitor PQR309 inhibits proliferation and induces apoptosis in human glioblastoma cells. Oncology Reports. PMID 32020210 DOI: 10.3892/or.2020.7472   
2020 Chen YT, Hsieh MJ, Chen PN, Weng CJ, Yang SF, Lin CW. Erianin Induces Apoptosis and Autophagy in Oral Squamous Cell Carcinoma Cells. The American Journal of Chinese Medicine. 1-18. PMID 31903779 DOI: 10.1142/S0192415X2050010X   
2020 Qiao H, Tan X, Lv DJ, Xing RW, Shu FP, Zhong CF, Li C, Zou YG, Mao XM. Phosphoribosyl pyrophosphate synthetases 2 knockdown inhibits prostate cancer progression by suppressing cell cycle and inducing cell apoptosis. Journal of Cancer. 11: 1027-1037. PMID 31956349 DOI: 10.7150/jca.37401   
2020 Lu CH, Kuo YY, Lin GB, Chen WT, Chao CY. Application of non-invasive low-intensity pulsed electric field with thermal cycling-hyperthermia for synergistically enhanced anticancer effect of chlorogenic acid on PANC-1 cells. Plos One. 15: e0222126. PMID 31995555 DOI: 10.1371/journal.pone.0222126   
2020 Gao Y, Ma C, Feng X, Haimiti X, Liu Y. BF12, a novel benzofuran, exhibits anti-tumor activity by inhibiting microtubules and the PI3K/Akt/mTOR signaling pathway in human cervical cancer cells. Chemistry & Biodiversity. PMID 31951313 DOI: 10.1002/cbdv.201900622   
2020 Gao Y, Li L, Hou L, Niu B, Ru X, Zhang D. SOX12 promotes the growth of multiple myeloma cells by enhancing Wnt/β-catenin signaling. Experimental Cell Research. 111814. PMID 31904384 DOI: 10.1016/j.yexcr.2020.111814   
2020 Li W, Du H, Zhou G, Song D. Euxanthone Represses the Proliferation, Migration, and Invasion of Glioblastoma Cells by modulating STAT3/SHP-1 signalling. Anatomical Record (Hoboken, N.J. : 2007). PMID 31922313 DOI: 10.1002/ar.24363   
2020 Luo X, Han G, Lu R, Guan S, Wang Y, Ju L, Chen L, Shao J, Bian Z. Transmembrane protein 106C promotes the development of hepatocellular carcinoma. Journal of Cellular Biochemistry. PMID 32037603 DOI: 10.1002/jcb.29678   
2020 Chowdhury P, Dey P, De D, Ghosh U. Gamma ray induced cell migration via EGFR/ERK/Akt/p38 activation is prevented by olaparib pre-treatment. International Journal of Radiation Biology. 1-26. PMID 31914341 DOI: 10.1080/09553002.2020.1711461   
2020 de Oliveira Ribeiro H, Pereira Cortez A, de Ávila RI, Christian Garcia da Silva A, de Carvalho FS, Menegatti R, Lião LM, Valadares MC. Small-molecule MDM2 inhibitor LQFM030-induced apoptosis in p53-null K562 chronic myeloid leukemia cells. Fundamental & Clinical Pharmacology. PMID 32011031 DOI: 10.1111/fcp.12540   
2020 Ke X, Qin Q, Deng T, Liao Y, Gao SJ. Heterogeneous Responses of Gastric Cancer Cell Lines to Tenovin-6 and Synergistic Effect with Chloroquine. Cancers. 12. PMID 32033497 DOI: 10.3390/cancers12020365   
2020 Rozpędek W, Pytel D, Wawrzynkiewicz A, Siwecka N, Dziki A, Dziki Ł, Diehl JA, Majsterek I. Use of small-molecule inhibitory compound of PERK-dependent signaling pathway as a promising target-based therapy for colorectal cancer. Current Cancer Drug Targets. PMID 31906838 DOI: 10.2174/1568009620666200106114826   
2020 Zhang X, Liu P, Shang Y, Kerndl H, Kumstel S, Gong P, Vollmar B, Zechner D. Metformin and LW6 impairs pancreatic cancer cells and reduces nuclear localization of YAP1. Journal of Cancer. 11: 479-487. PMID 31897243 DOI: 10.7150/jca.33029   
2020 Chakraborty S, Mir KB, Seligson ND, Nayak D, Kumar R, Goswami A. Integration of EMT and cellular survival instincts in reprogramming of programmed cell death to anastasis. Cancer Metastasis Reviews. PMID 32020420 DOI: 10.1007/s10555-020-09866-x   
2020 Ding J, Qin D, Zhang Y, Li Q, Li Y, Li J. SMAC mimetic birinapant inhibits hepatocellular carcinoma growth by activating the cIAP1/TRAF3 signaling pathway. Molecular Medicine Reports. PMID 31922244 DOI: 10.3892/mmr.2020.10908   
2020 Li J, Zheng L, Yan M, Wu J, Liu Y, Tian X, Jiang W, Zhang L, Wang R. Activity and mechanism of flavokawain A in inhibiting P-glycoprotein expression in paclitaxel resistance of lung cancer. Oncology Letters. 19: 379-387. PMID 31897150 DOI: 10.3892/ol.2019.11069   
2020 Akter M, Jangra A, Choi SA, Choi EH, Han I. Non-Thermal Atmospheric Pressure Bio-Compatible Plasma Stimulates Apoptosis via p38/MAPK Mechanism in U87 Malignant Glioblastoma. Cancers. 12. PMID 31963881 DOI: 10.3390/cancers12010245   
2020 Liao XZ, Gao Y, Sun LL, Liu JH, Chen HR, Yu L, Chen ZZ, Chen WH, Lin LZ. Rosmarinic acid reverses non-small cell lung cancer cisplatin resistance by activating the MAPK signaling pathway. Phytotherapy Research : Ptr. PMID 31985119 DOI: 10.1002/ptr.6584   
2020 Shanmugapriya K, Kim H, Lee YW, Kang HW. Cellulose nanocrystals/nanofibrils loaded astaxanthin nanoemulsion for the induction of apoptosis via ROS-dependent mitochondrial dysfunction in cancer cells under photobiomodulation. International Journal of Biological Macromolecules. PMID 31987944 DOI: 10.1016/j.ijbiomac.2020.01.243   
2020 Sheng LX, Zhang JY, Li L, Xie X, Wen XA, Cheng KG. Design, Synthesis, and Evaluation of Novel 2-Methoxyestradiol Derivatives as Apoptotic Inducers Through an Intrinsic Apoptosis Pathway. Biomolecules. 10. PMID 31936880 DOI: 10.3390/biom10010123   
2020 Wang L, Wang L, Wei S, Wang X, Shen D. The Effects of (11R)-13-(6-Nitroindazole)-11,13-Dihydroludartin on Human Prostate Carcinoma Cells and Mouse Tumor Xenografts. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 26: e920389. PMID 32036379 DOI: 10.12659/MSM.920389   
2020 Li J, Vangundy Z, Poi M. Cisplatin Induced the Expression of () Oncogene in Human Oral Squamous Cancer Cell Lines. Anticancer Research. 40: 67-73. PMID 31892553 DOI: 10.21873/anticanres.13926   
2020 Hernandes C, Miguita L, de Sales RO, Silva EP, Mendonça POR, Lorencini da Silva B, Klingbeil MFG, Mathor MB, Rangel EB, Marti LC, Coppede JDS, Nunes FD, Pereira AMS, Severino P. Anticancer Activities of the Quinone-Methide Triterpenes Maytenin and 22-β-hydroxymaytenin Obtained from Cultivated Roots Associated with Down-Regulation of miRNA-27a and miR-20a/miR-17-5p. Molecules (Basel, Switzerland). 25. PMID 32050628 DOI: 10.3390/molecules25030760   
2020 Ma Q, Hou L, Gao X, Yan K. NKAP promotes renal cell carcinoma growth via AKT/mTOR signalling pathway. Cell Biochemistry and Function. PMID 32032976 DOI: 10.1002/cbf.3508   
2020 Peng SY, Hsiao CC, Lan TH, Yen CY, Farooqi AA, Cheng CM, Tang JY, Yu TJ, Yeh YC, Chuang YT, Chiu CC, Chang HW. Pomegranate extract inhibits migration and invasion of oral cancer cells by downregulating matrix metalloproteinase-2/9 and epithelial-mesenchymal transition. Environmental Toxicology. PMID 31995279 DOI: 10.1002/tox.22903   
2020 Lu Y, Zhang X, Wang J, Chen K. Exopolysaccharides isolated from Rhizopus nigricans induced colon cancer cell apoptosis in vitro and in vivo via activating the AMPK pathway. Bioscience Reports. PMID 31894839 DOI: 10.1042/BSR20192774   
2020 Hu X, Han T, Bian Y, Tong H, Wen X, Li Y, Wan X. Knockdown of SLCO4C1 inhibits cell proliferation and metastasis in endometrial cancer through inactivating the PI3K/Akt signaling pathway. Oncology Reports. PMID 32020231 DOI: 10.3892/or.2020.7478   
2020 Markezana A, Ahmed M, Kumar G, Zorde-Khvalevsky E, Rozenblum N, Galun E, Goldberg SN. Moderate hyperthermic heating encountered during thermal ablation increases tumor cell activity. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 37: 119-129. PMID 31969029 DOI: 10.1080/02656736.2020.1714084   
2020 Saraiva N, Costa JG, Reis C, Almeida N, Rijo P, Fernandes AS. Anti-Migratory and Pro-Apoptotic Properties of Parvifloron D on Triple-Negative Breast Cancer Cells. Biomolecules. 10. PMID 31963771 DOI: 10.3390/biom10010158   
2020 Hafezi K, Hemmati AA, Abbaszadeh H, Valizadeh A, Makvandi M. Anticancer activity and molecular mechanisms of α-conidendrin, a polyphenolic compound present in Taxus yunnanensis, on human breast cancer cell lines. Phytotherapy Research : Ptr. PMID 31971313 DOI: 10.1002/ptr.6613   
2020 Hafezi K, Hemmati AA, Abbaszadeh H, Valizadeh A, Makvandi M. Anticancer activity and molecular mechanisms of α-conidendrin, a polyphenolic compound present in Taxus yunnanensis, on human breast cancer cell lines. Phytotherapy Research : Ptr. PMID 31971313 DOI: 10.1002/ptr.6613   
2020 Sp N, Kang DY, Jo ES, Rugamba A, Kim WS, Park YM, Hwang DY, Yoo JS, Liu Q, Jang KJ, Yang YM. Tannic Acid Promotes TRAIL-Induced Extrinsic Apoptosis by Regulating Mitochondrial ROS in Human Embryonic Carcinoma Cells. Cells. 9. PMID 31979292 DOI: 10.3390/cells9020282   
2020 Turnham DJ, Yang WW, Davies J, Varnava A, Ridley AJ, Conlan RS, Clarkson RWE. Bcl-3 promotes multi-modal tumour cell migration via NF-κB1 mediated regulation of Cdc42. Carcinogenesis. PMID 31957805 DOI: 10.1093/carcin/bgaa005   
2020 Fu Y, Wang Z, Luo C, Wang Y, Wang Y, Zhong X, Zheng H. Downregulation of CXXC Finger Protein 4 Leads to a Tamoxifen-resistant Phenotype in Breast Cancer Cells Through Activation of the Wnt/β-catenin Pathway. Translational Oncology. 13: 423-440. PMID 31911277 DOI: 10.1016/j.tranon.2019.12.005   
2020 Freund E, Liedtke KR, Miebach L, Wende K, Heidecke A, Kaushik NK, Choi EH, Partecke LI, Bekeschus S. Identification of Two Kinase Inhibitors with Synergistic Toxicity with Low-Dose Hydrogen Peroxide in Colorectal Cancer Cells in vitro. Cancers. 12. PMID 31906582 DOI: 10.3390/cancers12010122   
2020 Lian X, Zhu C, Lin H, Gao Z, Li G, Zhang N, Cao B, Kang Y. Radiosensitization of HER2-positive esophageal cancer cells by pyrotinib. Bioscience Reports. PMID 32022229 DOI: 10.1042/BSR20194167   
2020 Ding YY, Luan JJ, Fan Y, Olatunji OJ, Song J, Zuo J. α-Mangostin reduced the viability of A594 cells in vitro by provoking ROS production through downregulation of NAMPT/NAD. Cell Stress & Chaperones. PMID 31898286 DOI: 10.1007/s12192-019-01063-2   
2020 Huang XB, Yuan LW, Shao J, Yang Y, Liu Y, Lu JJ, Chen L. Cytotoxic effects of flavonoids from root of in cancer cells. Natural Product Research. 1-6. PMID 31928368 DOI: 10.1080/14786419.2020.1712382   
2020 Luo C, Wang Y, Wei C, Chen Y, Ji Z. The anti-migration and anti-invasion effects of Bruceine D in human triple-negative breast cancer MDA-MB-231 cells. Experimental and Therapeutic Medicine. 19: 273-279. PMID 31853299 DOI: 10.3892/etm.2019.8187   
2020 Wang YY, Kwak JH, Lee KT, Deyou T, Jang YP, Choi JH. Isoflavones Isolated from the Seeds of Induced Apoptotic Cell Death in Human Ovarian Cancer Cells. Molecules (Basel, Switzerland). 25. PMID 31947862 DOI: 10.3390/molecules25010207   
2020 Bekeschus S, Eisenmann S, Sagwal SK, Bodnar Y, Moritz J, Poschkamp B, Stoffels I, Emmert S, Madesh M, Weltmann KD, von Woedtke T, Gandhirajan RK. xCT (SLC7A11) expression confers intrinsic resistance to physical plasma treatment in tumor cells. Redox Biology. 30: 101423. PMID 31931281 DOI: 10.1016/j.redox.2019.101423   
2020 Ling X, Li Y, Qiu F, Lu X, Yang L, Chen J, Li T, Wu D, Xiong H, Su W, Huang D, Chen J, Yang B, Zhao H, Xie C, et al. Down expression of decreases that of is associated with the lung cancer susceptibility and cigarette smoking history. Aging. 12. PMID 31901898 DOI: 10.18632/aging.102633   
2020 Gan D, He W, Yin H, Gou X. β-elemene enhances cisplatin-induced apoptosis in bladder cancer cells through the ROS-AMPK signaling pathway. Oncology Letters. 19: 291-300. PMID 31897141 DOI: 10.3892/ol.2019.11103   
2020 Dai W, Wu J, Wang D, Wang J. Cancer gene therapy by NF-κB-activated cancer cell-specific expression of CRISPR/Cas9 targeting telomeres. Gene Therapy. PMID 32034293 DOI: 10.1038/s41434-020-0128-x   
2020 Liu YT, Chuang YC, Lo YS, Lin CC, Hsi YT, Hsieh MJ, Chen MK. Asiatic Acid, Extracted from and Induces Apoptosis Pathway through the Phosphorylation p38 Mitogen-Activated Protein Kinase in Cisplatin-Resistant Nasopharyngeal Carcinoma Cells. Biomolecules. 10. PMID 31991751 DOI: 10.3390/biom10020184   
2020 Ahmad A, Ahsan H. Ras mediated activation of NF-κB and DNA damage response in carcinogenesis. Cancer Investigation. 1-58. PMID 31971023 DOI: 10.1080/07357907.2020.1721523   
2020 Shao G, Zhao Z, Zhao W, Hu G, Zhang L, Li W, Xing C, Zhang X. Long non-coding RNA MALAT1 activates autophagy and promotes cell proliferation by downregulating microRNA-204 expression in gastric cancer. Oncology Letters. 19: 805-812. PMID 31897197 DOI: 10.3892/ol.2019.11184