Robert V. Stahelin, Ph.D. - Publications

Affiliations: 
1998-2006 Chemistry University of Illinois at Chicago, Chicago, IL, United States 
 2006-2017 Chemistry and Biochemistry University of Notre Dame, Notre Dame, IN, United States 
 2006-2017 Biochemistry and Molecular Biology Indiana University School of Medicine-South Bend 
 2017- Medicinal Chemistry and Molecular Biology Purdue University, West Lafayette, IN, United States 
Area:
Biochemistry, General Biophysics, Cell Biology, Virology
Website:
https://thestahelinlab.weebly.com/

136 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Parvate A, Sengupta R, Williams EP, Xue Y, Chu YK, Stahelin RV, Jonsson CB. Cryofixation of Inactivated Hantavirus-Infected Cells as a Method for Obtaining High-Quality Ultrastructural Preservation for Electron Microscopic Studies. Frontiers in Cellular and Infection Microbiology. 10: 580339. PMID 33240823 DOI: 10.3389/fcimb.2020.580339  1
2020 Plescia CB, David EA, Patra D, Sengupta R, Amiar S, Su Y, Stahelin RV. SARS-CoV-2 viral budding and entry can be modeled using BSL-2 level virus-like particles. The Journal of Biological Chemistry. PMID 33214224 DOI: 10.1074/jbc.RA120.016148  1
2020 Plescia CB, David EA, Patra D, Sengupta R, Amiar S, Su Y, Stahelin RV. SARS-CoV-2 viral budding and entry can be modeled using virus-like particles. Biorxiv : the Preprint Server For Biology. PMID 33024964 DOI: 10.1101/2020.09.30.320903  1
2020 Smulders L, Daniels AJ, Plescia CB, Berger D, Stahelin RV, Nikolaidis N. Characterization of the Relationship between the Chaperone and Lipid-Binding Functions of the 70-kDa Heat-Shock Protein, HspA1A. International Journal of Molecular Sciences. 21. PMID 32825419 DOI: 10.3390/Ijms21175995  1
2020 Su Y, Stahelin RV. The Minor Matrix Protein VP24 from Ebola Virus Lacks Direct Lipid-Binding Properties. Viruses. 12. PMID 32784484 DOI: 10.3390/V12080869  0.96
2020 Ravala SK, Hopkins JB, Plescia CB, Allgood SR, Kane MA, Cash JN, Stahelin RV, Tesmer JJG. The first DEP domain of the RhoGEF P-Rex1 autoinhibits activity andcontributes to membrane binding. The Journal of Biological Chemistry. PMID 32661198 DOI: 10.1074/Jbc.Ra120.014534  1
2020 Abeywickrama CS, Wijesinghe KJ, Plescia CB, Fisher LS, Goodson Iii T, Stahelin RV, Pang Y. A pyrene-based two-photon excitable fluorescent probe to visualize nuclei in live cells. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. PMID 32639494 DOI: 10.1039/D0Pp00107D  1
2020 Johnson KA, Pokhrel R, Budicini MR, Gerstman BS, Chapagain PP, Stahelin RV. A Conserved Tryptophan in the Ebola Virus Matrix Protein C-Terminal Domain Is Required for Efficient Virus-Like Particle Formation. Pathogens (Basel, Switzerland). 9. PMID 32455873 DOI: 10.3390/Pathogens9050402  1
2020 Wijesinghe KJ, McVeigh L, Husby ML, Bhattarai N, Ma J, Gerstman BS, Chapagain PP, Stahelin RV. Mutation of Hydrophobic Residues in the C-Terminal Domain of the Marburg Virus Matrix Protein VP40 Disrupts Trafficking to the Plasma Membrane. Viruses. 12. PMID 32344654 DOI: 10.3390/V12040482  1
2020 Ward KE, Sengupta R, Ropa JP, Amiar S, Stahelin RV. The Cytosolic Phospholipase Aα N-terminal C2 Domain Binds and Oligomerizes on Membranes with Positive Curvature. Biomolecules. 10. PMID 32331436 DOI: 10.3390/biom10040647  1
2020 Amiar S, Stahelin RV. Ebola virus matrix protein VP40 hijacks the host plasma membrane to form the virus envelope. Journal of Lipid Research. PMID 32295828 DOI: 10.1194/Jlr.Ilr120000753  1
2020 Mihelc EM, Angel S, Stahelin RV, Mattoo S. The CryoAPEX Method for Electron Microscopy Analysis of Membrane Protein Localization Within Ultrastructurally-Preserved Cells. Journal of Visualized Experiments : Jove. PMID 32176196 DOI: 10.3791/60677  0.01
2020 Olson KR, Gao Y, Steiger AK, Pluth MD, Tessier CR, Markel TA, Boone D, Stahelin RV, Batinic-Haberle I, Straubg KD. Effects of Manganese Porphyrins on Cellular Sulfur Metabolism. Molecules (Basel, Switzerland). 25. PMID 32098303 DOI: 10.3390/Molecules25040980  1
2020 Scott JL, Frick CT, Johnson KA, Liu H, Yong SS, Varney AG, Wiest O, Stahelin RV. Molecular Analysis of Membrane Targeting by the C2 Domain of the E3 Ubiquitin Ligase Smurf1. Biomolecules. 10. PMID 32033048 DOI: 10.3390/biom10020229  1
2020 Stahelin RV. Assembly and Budding of Filoviruses from the Host Cell Plasma Membrane Biophysical Journal. 118: 480a. DOI: 10.1016/J.Bpj.2019.11.2657  0.01
2019 Abeywickrama CS, Wijesinghe KJ, Stahelin RV, Pang Y. Bright red-emitting highly reliable styryl probe with large Stokes shift for visualizing mitochondria in live cells under wash-free conditions. Sensors and Actuators. B, Chemical. 285: 76-83. PMID 31762582 DOI: 10.1016/J.Snb.2019.01.041  1
2019 Pavadai E, Bhattarai N, Baral P, Stahelin RV, Chapagain PP, Gerstman BS. Conformational Flexibility of the Protein-Protein Interfaces of the Ebola Virus VP40 Structural Matrix Filament. The Journal of Physical Chemistry. B. PMID 31576755 DOI: 10.1021/Acs.Jpcb.9B04674  1
2019 Olson KR, Gao Y, DeLeon ER, Markel TA, Drucker N, Boone D, Whiteman M, Steiger AK, Pluth MD, Tessier CR, Stahelin RV. Extended Hypoxia-Mediated H S Production Provides for Long-Term Oxygen Sensing. Acta Physiologica (Oxford, England). e13368. PMID 31442361 DOI: 10.1111/Apha.13368  1
2019 Abeywickrama CS, Wijesinghe KJ, Stahelin RV, Pang Y. Lysosome imaging in cancer cells by pyrene-benzothiazolium dyes: An alternative imaging approach for LAMP-1 expression based visualization methods to avoid background interference. Bioorganic Chemistry. 91: 103144. PMID 31377388 DOI: 10.1016/J.Bioorg.2019.103144  1
2019 Kimiti Kilili G, Shakya B, Dolan PT, Wang L, Husby ML, Stahelin RV, Nakayasu ES, LaCount DJ. The Plasmodium falciparum MESA erythrocyte cytoskeleton-binding (MEC) motif binds to erythrocyte ankyrin. Molecular and Biochemical Parasitology. 111189. PMID 31125575 DOI: 10.1016/J.Molbiopara.2019.111189  1
2019 Ebrahimzadeh Z, Mukherjee A, Crochetière MÈ, Sergerie A, Amiar S, Thompson LA, Gagnon D, Gaumond D, Stahelin RV, Dacks JB, Richard D. A pan-apicomplexan phosphoinositide-binding protein acts in malarial microneme exocytosis. Embo Reports. PMID 31097469 DOI: 10.15252/Embr.201847102  1
2019 Bilog AD, Smulders L, Oliverio R, Labanieh C, Zapanta J, Stahelin RV, Nikolaidis N. Membrane Localization of HspA1A, a Stress Inducible 70-kDa Heat-Shock Protein, Depends on Its Interaction with Intracellular Phosphatidylserine. Biomolecules. 9. PMID 30999671 DOI: 10.3390/biom9040152  0.08
2019 Abeywickrama CS, Wijesinghe KJ, Stahelin RV, Pang Y. Red-emitting pyrene-benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect. Chemical Communications (Cambridge, England). PMID 30839045 DOI: 10.1039/C9Cc01068H  1
2019 Abeywickrama CS, Bertman KA, Plescia CB, Stahelin RV, Pang Y. Structural Effect on the Cellular Selectivity of an NIR-Emitting Cyanine Probe: From Lysosome to Simultaneous Nucleus and Mitochondria Selectivity with Potential for Monitoring Mitochondria Dysfunction in Cells Acs Applied Bio Materials. 2: 5174-5181. DOI: 10.1021/acsabm.9b00810  0.01
2018 Nganga R, Oleinik N, Kim J, Panneer Selvam S, De Palma R, Johnson KA, Parikh RY, Gangaraju V, Peterson Y, Dany M, Stahelin RV, Voelkel-Johnson C, Szulc ZM, Bieberich E, Ogretmen B. Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis. The Journal of Biological Chemistry. PMID 30420430 DOI: 10.1074/Jbc.Ra118.005865  1
2018 Pei D, Appiah Kubi G, Qian Z, Amiar S, Sahni A, Stahelin RV. Non-Peptidic Cell-Penetrating Motifs for Mitochondrion-Specific Cargo Delivery. Angewandte Chemie (International Ed. in English). PMID 30376611 DOI: 10.1002/Anie.201811940  1
2018 Kuc N, Doermann A, Shirey C, Lee DD, Lowe CW, Awasthi N, Schwarz RE, Stahelin RV, Schwarz MA. Pancreatic Ductal Adenocarcinoma Cell Secreted Extracellular Vesicles Containing Ceramide-1-Phosphate Promote Pancreatic Cancer Stem Cell Motility. Biochemical Pharmacology. PMID 30222969 DOI: 10.1016/J.Bcp.2018.09.017  0.01
2018 Del Vecchio K, Stahelin RV. Investigation of the phosphatidylserine binding properties of the lipid biosensor, Lactadherin C2 (LactC2), in different membrane environments. Journal of Bioenergetics and Biomembranes. PMID 29426977 DOI: 10.1007/S10863-018-9745-0  1
2018 Stahelin RV. The unmasking of the lipid binding face of sphingosine kinase 1. Journal of Lipid Research. PMID 29382689 DOI: 10.1194/Jlr.C083907  0.01
2018 Bhattacharjee S, Coppens I, Mbengue A, Suresh N, Ghorbal M, Slouka Z, Safeukui I, Tang HY, Speicher DW, Stahelin RV, Mohandas N, Haldar K. Remodeling of the malaria parasite and host human red cell by vesicle amplification that induces artemisinin resistance. Blood. PMID 29363540 DOI: 10.1182/Blood-2017-11-814665  1
2018 Del Vecchio K, Frick CT, Gc JB, Oda SI, Gerstman BS, Saphire EO, Chapagain PP, Stahelin RV. A cationic, C-terminal patch and structural rearrangements in Ebola virus matrix VP40 protein control its interactions with phosphatidylserine. The Journal of Biological Chemistry. PMID 29348171 DOI: 10.1074/Jbc.M117.816280  1
2017 Gc JB, Pokhrel R, Bhattarai N, Johnson KA, Gerstman BS, Stahelin RV, Chapagain PP. Graphene-VP40 interactions and potential disruption of the Ebola virus matrix filaments. Biochemical and Biophysical Research Communications. PMID 28917841 DOI: 10.1016/J.Bbrc.2017.09.052  1
2017 Ahn G, Kim H, Kim DH, Hanh NH, Yoon Y, Singaram I, Wijesinghe KJ, Johnson KA, Zhuang XH, Liang Z, Stahelin RV, Jiang L, Cho W, Kang BH, Hwang I. SH3P2 plays a crucial role at the step of membrane tubulation during cell plate formation in plants. The Plant Cell. PMID 28584166 DOI: 10.1105/Tpc.17.00108  1
2017 Bhattarai N, Gc JB, Gerstman BS, Stahelin RV, Chapagain PP. Plasma membrane association facilitates conformational changes in the Marburg virus protein VP40 dimer. Rsc Advances. 7: 22741-22748. PMID 28580138 DOI: 10.1039/C7Ra02940C  1
2017 Abeywickrama CS, Wijesinghe KJ, Stahelin RV, Pang Y. Bright red-emitting pyrene derivatives with a large Stokes shift for nucleus staining. Chemical Communications (Cambridge, England). PMID 28509921 DOI: 10.1039/C7Cc03417B  1
2017 Wijesinghe KJ, Urata S, Bhattarai N, Kooijman EE, Gerstman BS, Chapagain PP, Li S, Stahelin RV. Detection of Lipid Induced Structural Changes of the Marburg Virus Matrix Protein VP40 Using Hydrogen/Deuterium Exchange Mass Spectrometry. The Journal of Biological Chemistry. PMID 28167534 DOI: 10.1074/Jbc.M116.758300  1
2016 Gc JB, Gerstman BS, Stahelin RV, Chapagain PP. The Ebola virus protein VP40 hexamer enhances the clustering of PI(4,5)P2 lipids in the plasma membrane. Physical Chemistry Chemical Physics : Pccp. 18: 28409-28417. PMID 27757455 DOI: 10.1039/C6Cp03776C  1
2016 Shirey CM, Scott JL, Stahelin RV. Notes and tips for improving quality of lipid-protein overlay assays. Analytical Biochemistry. PMID 27742211 DOI: 10.1016/J.Ab.2016.10.009  1
2016 Gc JB, Johnson KA, Husby ML, Frick CT, Gerstman BS, Stahelin RV, Chapagain PP. Interdomain salt-bridges in the Ebola virus protein VP40 and their role in domain association and plasma membrane localization. Protein Science : a Publication of the Protein Society. PMID 27328459 DOI: 10.1002/Pro.2969  1
2016 Shirey CM, Ward KE, Stahelin RV. Investigation of the biophysical properties of a fluorescently modified ceramide-1-phosphate. Chemistry and Physics of Lipids. PMID 27318040 DOI: 10.1016/J.Chemphyslip.2016.06.004  1
2016 Johnson KA, Taghon GJ, Scott JL, Stahelin RV. The Ebola Virus matrix protein, VP40, requires phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) for extensive oligomerization at the plasma membrane and viral egress. Scientific Reports. 6: 19125. PMID 26753796 DOI: 10.1038/Srep19125  1
2016 Del Vecchio K, Stahelin RV. Using Surface Plasmon Resonance to Quantitatively Assess Lipid-Protein Interactions. Methods in Molecular Biology (Clifton, N.J.). 1376: 141-53. PMID 26552681 DOI: 10.1007/978-1-4939-3170-5_12  1
2015 Wijesinghe KJ, Stahelin RV. Investigation of the Lipid Binding Properties of the Marburg Virus Matrix Protein VP40. Journal of Virology. 90: 3074-85. PMID 26719280 DOI: 10.1128/Jvi.02607-15  1
2015 Oda SI, Noda T, Wijesinghe KJ, Halfmann P, Bornholdt ZA, Abelson DM, Armbrust T, Stahelin RV, Kawaoka Y, Saphire EO. Crystal structure of Marburg virus VP40: matrix assembly and immunosuppression. Journal of Virology. PMID 26656687 DOI: 10.1128/Jvi.01597-15  1
2015 Stahelin RV. Time to Fold: Tom1 Uses New Tricks to Regulate Lipid Binding of Tollip. Structure (London, England : 1993). 23: 1781-2. PMID 26445490 DOI: 10.1016/J.Str.2015.09.003  1
2015 Stahelin RV. The Ebola Virus: From Basic Research to a Global Health Crisis. Plos Pathogens. 11: e1005093. PMID 26270052 DOI: 10.1371/Journal.Ppat.1005093  1
2015 Adu-Gyamfi E, Johnson KA, Fraser ME, Scott JL, Soni SP, Jones KR, Digman MA, Gratton E, Tessier CR, Stahelin RV. Host Cell Plasma Membrane Phosphatidylserine Regulates the Assembly and Budding of Ebola Virus. Journal of Virology. 89: 9440-53. PMID 26136573 DOI: 10.1128/Jvi.01087-15  0.92
2015 Panneer Selvam S, De Palma RM, Oaks JJ, Oleinik N, Peterson YK, Stahelin RV, Skordalakes E, Ponnusamy S, Garrett-Mayer E, Smith CD, Ogretmen B. Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Science Signaling. 8: ra58. PMID 26082434 DOI: 10.1126/Scisignal.Aaa4998  1
2015 Mbengue A, Bhattacharjee S, Pandharkar T, Liu H, Estiu G, Stahelin RV, Rizk SS, Njimoh DL, Ryan Y, Chotivanich K, Nguon C, Ghorbal M, Lopez-Rubio JJ, Pfrender M, Emrich S, et al. A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria. Nature. 520: 683-7. PMID 25874676 DOI: 10.1038/Nature14412  1
2015 Frick CT, Stahelin RV. The Ebola Virus Matrix Protein VP40 Interacts With Several Host Protein Networks to Facilitate Viral Replication Current Clinical Microbiology Reports. 2: 137-141. DOI: 10.1007/s40588-015-0022-2  0.01
2014 Adu-Gyamfi E, Soni SP, Jee CS, Digman MA, Gratton E, Stahelin RV. A loop region in the N-terminal domain of Ebola virus VP40 is important in viral assembly, budding, and egress. Viruses. 6: 3837-54. PMID 25330123 DOI: 10.3390/V6103837  1
2014 Soni SP, Stahelin RV. The Ebola virus matrix protein VP40 selectively induces vesiculation from phosphatidylserine-enriched membranes. The Journal of Biological Chemistry. 289: 33590-7. PMID 25315776 DOI: 10.1074/Jbc.M114.586396  1
2014 Stahelin RV. Membrane binding and bending in Ebola VP40 assembly and egress. Frontiers in Microbiology. 5: 300. PMID 24995005 DOI: 10.3389/Fmicb.2014.00300  1
2014 Stahelin RV. Ready, set, go! How protein kinase C manages dynamic signaling. Chemistry & Biology. 21: 433-4. PMID 24766842 DOI: 10.1016/J.Chembiol.2014.04.003  1
2014 Stahelin RV, Scott JL, Frick CT. Cellular and molecular interactions of phosphoinositides and peripheral proteins. Chemistry and Physics of Lipids. 182: 3-18. PMID 24556335 DOI: 10.1016/J.Chemphyslip.2014.02.002  1
2014 Stahelin RV. Could the Ebola virus matrix protein VP40 be a drug target? Expert Opinion On Therapeutic Targets. 18: 115-20. PMID 24283270 DOI: 10.1517/14728222.2014.863877  1
2014 Ward KE, Ropa JP, Stahelin RV. Characterizing the Curve: A Mechanistic Study of CPLA2-Mediated Membrane Bending Biophysical Journal. 106: 91a. DOI: 10.1016/J.Bpj.2013.11.578  0.01
2014 Soni SP, Stahelin RV. The Ebola Virus Matrix Protein Bends Biological Membranes Biophysical Journal. 106: 513a. DOI: 10.1016/J.Bpj.2013.11.2868  0.01
2014 Scott JL, Stahelin RV. Novel Properties of the Smurf1 C2 Domain in Cellular Lipid Binding Biophysical Journal. 106: 301a-302a. DOI: 10.1016/J.Bpj.2013.11.1753  0.01
2014 Stahelin RV. Molecular Basis of the Assembly and Budding of the Ebola Virus from the Plasma Membrane of Human Cells Biophysical Journal. 106: 2a. DOI: 10.1016/J.Bpj.2013.11.040  0.01
2013 Stahelin RV. Monitoring peripheral protein oligomerization on biological membranes. Methods in Cell Biology. 117: 359-71. PMID 24143987 DOI: 10.1016/B978-0-12-408143-7.00019-0  1
2013 Stahelin RV. A new model of interfacial kinetics for phospholipases. Biophysical Journal. 105: 1-2. PMID 23823217 DOI: 10.1016/J.Bpj.2013.03.044  1
2013 Hankins JL, Ward KE, Linton SS, Barth BM, Stahelin RV, Fox TE, Kester M. Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complex. The Journal of Biological Chemistry. 288: 19726-38. PMID 23696646 DOI: 10.1074/Jbc.M113.481622  1
2013 Soni SP, Adu-Gyamfi E, Yong SS, Jee CS, Stahelin RV. The Ebola virus matrix protein deeply penetrates the plasma membrane: an important step in viral egress. Biophysical Journal. 104: 1940-9. PMID 23663837 DOI: 10.1016/J.Bpj.2013.03.021  1
2013 Stahelin RV. Surface plasmon resonance: a useful technique for cell biologists to characterize biomolecular interactions. Molecular Biology of the Cell. 24: 883-6. PMID 23533209 DOI: 10.1091/Mbc.E12-10-0713  1
2013 Jiang RH, Stahelin RV, Bhattacharjee S, Haldar K. Eukaryotic virulence determinants utilize phosphoinositides at the ER and host cell surface. Trends in Microbiology. 21: 145-56. PMID 23375057 DOI: 10.1016/J.Tim.2012.12.004  1
2013 Adu-Gyamfi E, Soni SP, Xue Y, Digman MA, Gratton E, Stahelin RV. The Ebola virus matrix protein penetrates into the plasma membrane: a key step in viral protein 40 (VP40) oligomerization and viral egress. The Journal of Biological Chemistry. 288: 5779-89. PMID 23297401 DOI: 10.1074/Jbc.M112.443960  1
2013 Ward KE, Bhardwaj N, Vora M, Chalfant CE, Lu H, Stahelin RV. The molecular basis of ceramide-1-phosphate recognition by C2 domains. Journal of Lipid Research. 54: 636-48. PMID 23277511 DOI: 10.1194/Jlr.M031088  1
2013 Saddoughi SA, Gencer S, Peterson YK, Ward KE, Mukhopadhyay A, Oaks J, Bielawski J, Szulc ZM, Thomas RJ, Selvam SP, Senkal CE, Garrett-Mayer E, De Palma RM, Fedarovich D, Liu A, ... ... Stahelin RV, et al. Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis. Embo Molecular Medicine. 5: 105-21. PMID 23180565 DOI: 10.1002/Emmm.201201283  1
2013 Scott JL, Stahelin RV. Spatial and Temporal Regulation of the Nedd4 Family of E3 Ubiquitin Ligases through Phospholipid Binding Biophysical Journal. 104: 595a. DOI: 10.1016/J.Bpj.2012.11.3304  0.01
2013 Soni SP, Adu-Gyamfi E, Stahelin RV, Leblang C. Membrane Penetrating Ability of Ebola Matrix Protein, VP40 Biophysical Journal. 104: 595a. DOI: 10.1016/J.Bpj.2012.11.3303  0.01
2013 Adu-Gyamfi E, Soni SP, Stahelin RV. Elucidating the Mechanism of Ebola Virus Assembly and Budding Biophysical Journal. 104: 416a. DOI: 10.1016/J.Bpj.2012.11.2316  0.01
2013 Ward KE, Ropa JP, Adu-Gyamfi E, Stahelin RV. Investigating the Molecular Basis of cPLA2α Membrane Bending Biophysical Journal. 104: 363a. DOI: 10.1016/J.Bpj.2012.11.2017  0.01
2012 Adu-Gyamfi E, Digman MA, Gratton E, Stahelin RV. Single-particle tracking demonstrates that actin coordinates the movement of the Ebola virus matrix protein. Biophysical Journal. 103: L41-3. PMID 23199932 DOI: 10.1016/J.Bpj.2012.09.026  1
2012 Bhattacharjee S, Stahelin RV, Haldar K. Host targeting of virulence determinants and phosphoinositides in blood stage malaria parasites. Trends in Parasitology. 28: 555-62. PMID 23084821 DOI: 10.1016/J.Pt.2012.09.004  1
2012 Ward KE, Ropa JP, Adu-Gyamfi E, Stahelin RV. C2 domain membrane penetration by group IVA cytosolic phospholipase A₂ induces membrane curvature changes. Journal of Lipid Research. 53: 2656-66. PMID 22991194 DOI: 10.1194/Jlr.M030718  1
2012 Bhattacharjee S, Speicher KD, Stahelin RV, Speicher DW, Haldar K. PI(3)P-independent and -dependent pathways function together in a vacuolar translocation sequence to target malarial proteins to the host erythrocyte. Molecular and Biochemical Parasitology. 185: 106-13. PMID 22828070 DOI: 10.1016/J.Molbiopara.2012.07.004  1
2012 Stahelin RV, Kong KF, Raha S, Tian W, Melowic HR, Ward KE, Murray D, Altman A, Cho W. Protein kinase Cθ C2 domain is a phosphotyrosine binding module that plays a key role in its activation. The Journal of Biological Chemistry. 287: 30518-28. PMID 22787157 DOI: 10.1074/Jbc.M112.391557  1
2012 Adu-Gyamfi E, Digman MA, Gratton E, Stahelin RV. Investigation of Ebola VP40 assembly and oligomerization in live cells using number and brightness analysis. Biophysical Journal. 102: 2517-25. PMID 22713567 DOI: 10.1016/J.Bpj.2012.04.022  1
2012 Scott JL, Musselman CA, Adu-Gyamfi E, Kutateladze TG, Stahelin RV. Emerging methodologies to investigate lipid-protein interactions. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 247-58. PMID 22327461 DOI: 10.1039/C2Ib00143H  1
2012 Bhattacharjee S, Stahelin RV, Speicher KD, Speicher DW, Haldar K. Endoplasmic reticulum PI(3)P lipid binding targets malaria proteins to the host cell. Cell. 148: 201-12. PMID 22265412 DOI: 10.1016/J.Cell.2011.10.051  1
2011 He J, Gajewiak J, Scott JL, Gong D, Ali M, Best MD, Prestwich GD, Stahelin RV, Kutateladze TG. Metabolically stabilized derivatives of phosphatidylinositol 4-phosphate: synthesis and applications. Chemistry & Biology. 18: 1312-9. PMID 22035800 DOI: 10.1016/J.Chembiol.2011.07.022  1
2011 Lamour NF, Wijesinghe DS, Mietla JA, Ward KE, Stahelin RV, Chalfant CE. Ceramide kinase regulates the production of tumor necrosis factor α (TNFα) via inhibition of TNFα-converting enzyme. The Journal of Biological Chemistry. 286: 42808-17. PMID 22009748 DOI: 10.1074/Jbc.M111.310169  1
2011 Lamour NF, Wijesinghe DS, Mietla JA, Ward KE, Stahelin RV, Chalfant CE. WITHDRAWN: Ceramide kinase regulates the production of TNF{alpha} via inhibition of TNF{alpha}-converting enzyme. The Journal of Biological Chemistry. PMID 21896476 DOI: 10.1074/Jbc.M111.276048  1
2011 Lumb CN, He J, Xue Y, Stansfeld PJ, Stahelin RV, Kutateladze TG, Sansom MS. Biophysical and computational studies of membrane penetration by the GRP1 pleckstrin homology domain. Structure (London, England : 1993). 19: 1338-46. PMID 21893292 DOI: 10.1016/J.Str.2011.04.010  1
2011 Silkov A, Yoon Y, Lee H, Gokhale N, Adu-Gyamfi E, Stahelin RV, Cho W, Murray D. Genome-wide structural analysis reveals novel membrane binding properties of AP180 N-terminal homology (ANTH) domains. The Journal of Biological Chemistry. 286: 34155-63. PMID 21828048 DOI: 10.1074/Jbc.M111.265611  1
2011 He J, Scott JL, Heroux A, Roy S, Lenoir M, Overduin M, Stahelin RV, Kutateladze TG. Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain. The Journal of Biological Chemistry. 286: 18650-7. PMID 21454700 DOI: 10.1074/Jbc.M111.233015  1
2010 Li XJ, Marchal CC, Stull ND, Stahelin RV, Dinauer MC. p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation. The Journal of Biological Chemistry. 285: 35169-79. PMID 20817944 DOI: 10.1074/Jbc.M110.164475  1
2010 Heller B, Adu-Gyamfi E, Smith-Kinnaman W, Babbey C, Vora M, Xue Y, Bittman R, Stahelin RV, Wells CD. Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain. The Journal of Biological Chemistry. 285: 12308-20. PMID 20080965 DOI: 10.1074/Jbc.M109.096230  1
2009 Smith MD, Sudhahar CG, Gong D, Stahelin RV, Best MD. Modular synthesis of biologically active phosphatidic acid probes using click chemistry. Molecular Biosystems. 5: 962-72. PMID 19668861 DOI: 10.1039/B901420A  1
2009 Lamour NF, Subramanian P, Wijesinghe DS, Stahelin RV, Bonventre JV, Chalfant CE. Ceramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis. The Journal of Biological Chemistry. 284: 26897-907. PMID 19632995 DOI: 10.1074/Jbc.M109.001677  0.28
2009 He J, Vora M, Haney RM, Filonov GS, Musselman CA, Burd CG, Kutateladze AG, Verkhusha VV, Stahelin RV, Kutateladze TG. Membrane insertion of the FYVE domain is modulated by pH. Proteins. 76: 852-60. PMID 19296456 DOI: 10.1002/Prot.22392  1
2009 Stahelin RV. Lipid binding domains: more than simple lipid effectors. Journal of Lipid Research. 50: S299-304. PMID 19008549 DOI: 10.1194/Jlr.R800078-Jlr200  1
2008 Sudhahar CG, Haney RM, Xue Y, Stahelin RV. Cellular membranes and lipid-binding domains as attractive targets for drug development Current Drug Targets. 9: 603-613. PMID 18691008 DOI: 10.2174/138945008785132420  1
2008 Stahelin RV. Peripheral proteins as drug targets. Current Drug Targets. 9: 601-2. PMID 18691007 DOI: 10.2174/138945008785132448  1
2008 Smith MD, Gong D, Sudhahar CG, Reno JC, Stahelin RV, Best MD. Synthesis and convenient functionalization of azide-labeled diacylglycerol analogues for modular access to biologically active lipid probes. Bioconjugate Chemistry. 19: 1855-63. PMID 18683963 DOI: 10.1021/Bc8001002  1
2008 Manna D, Bhardwaj N, Vora MS, Stahelin RV, Lu H, Cho W. Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain. The Journal of Biological Chemistry. 283: 26047-58. PMID 18621733 DOI: 10.1074/Jbc.M802617200  1
2008 He J, Haney RM, Vora M, Verkhusha VV, Stahelin RV, Kutateladze TG. Molecular mechanism of membrane targeting by the GRP1 PH domain. Journal of Lipid Research. 49: 1807-15. PMID 18469301 DOI: 10.1194/Jlr.M800150-Jlr200  1
2008 Hanshaw RG, Stahelin RV, Smith BD. Noncovalent keystone interactions controlling biomembrane structure. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 1690-7. PMID 18085538 DOI: 10.1002/Chem.200701589  1
2007 Subramanian P, Vora M, Gentile LB, Stahelin RV, Chalfant CE. Anionic lipids activate group IVA cytosolic phospholipase A2 via distinct and separate mechanisms. Journal of Lipid Research. 48: 2701-8. PMID 17890681 DOI: 10.1194/Jlr.M700356-Jlr200  1
2007 Hom RA, Vora M, Regner M, Subach OM, Cho W, Verkhusha VV, Stahelin RV, Kutateladze TG. pH-dependent binding of the Epsin ENTH domain and the AP180 ANTH domain to PI(4,5)P2-containing bilayers. Journal of Molecular Biology. 373: 412-23. PMID 17825837 DOI: 10.1016/J.Jmb.2007.08.016  1
2007 Bhardwaj N, Stahelin RV, Zhao G, Cho W, Lu H. MeTaDoR: a comprehensive resource for membrane targeting domains and their host proteins. Bioinformatics (Oxford, England). 23: 3110-2. PMID 17720983 DOI: 10.1093/Bioinformatics/Btm395  1
2007 Stahelin RV, Karathanassis D, Murray D, Williams RL, Cho W. Structural and membrane binding analysis of the Phox homology domain of Bem1p: basis of phosphatidylinositol 4-phosphate specificity. The Journal of Biological Chemistry. 282: 25737-47. PMID 17581820 DOI: 10.1074/Jbc.M702861200  1
2007 Melowic HR, Stahelin RV, Blatner NR, Tian W, Hayashi K, Altman A, Cho W. Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Ctheta. The Journal of Biological Chemistry. 282: 21467-76. PMID 17548359 DOI: 10.1074/Jbc.M700119200  1
2007 Stahelin RV, Subramanian P, Vora M, Cho W, Chalfant CE. Ceramide-1-phosphate binds group IVA cytosolic phospholipase a2 via a novel site in the C2 domain. The Journal of Biological Chemistry. 282: 20467-74. PMID 17472963 DOI: 10.1074/Jbc.M701396200  1
2007 Lamour NF, Stahelin RV, Wijesinghe DS, Maceyka M, Wang E, Allegood JC, Merrill AH, Cho W, Chalfant CE. Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis. Journal of Lipid Research. 48: 1293-304. PMID 17392267 DOI: 10.1194/Jlr.M700083-Jlr200  1
2007 Lee SA, Regner MA, Stahelin R, Verkhusha VV, Burd CG, Cho W, Kutateladze TG. Membrane docking by PI‐binding domains The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A603-C  0.01
2006 Málková S, Stahelin RV, Pingali SV, Cho W, Schlossman ML. Orientation and penetration depth of monolayer-bound p40phox-PX. Biochemistry. 45: 13566-75. PMID 17087510 DOI: 10.1021/Bi061133L  1
2006 Stahelin RV, Karathanassis D, Bruzik KS, Waterfield MD, Bravo J, Williams RL, Cho W. Structural and membrane binding analysis of the Phox homology domain of phosphoinositide 3-kinase-C2alpha. The Journal of Biological Chemistry. 281: 39396-406. PMID 17038310 DOI: 10.1074/Jbc.M607079200  1
2006 Mallikaratchy P, Stahelin RV, Cao Z, Cho W, Tan W. Selection of DNA ligands for protein kinase C-delta. Chemical Communications (Cambridge, England). 3229-31. PMID 17028752 DOI: 10.1039/B604778E  1
2006 Lee SA, Kovacs J, Stahelin RV, Cheever ML, Overduin M, Setty TG, Burd CG, Cho W, Kutateladze TG. Molecular mechanism of membrane docking by the Vam7p PX domain. The Journal of Biological Chemistry. 281: 37091-101. PMID 16984909 DOI: 10.1074/Jbc.M608610200  1
2006 Cho W, Stahelin RV. Membrane binding and subcellular targeting of C2 domains. Biochimica Et Biophysica Acta. 1761: 838-49. PMID 16945584 DOI: 10.1016/J.Bbalip.2006.06.014  1
2006 Bhardwaj N, Stahelin RV, Langlois RE, Cho W, Lu H. Structural bioinformatics prediction of membrane-binding proteins. Journal of Molecular Biology. 359: 486-95. PMID 16626739 DOI: 10.1016/J.Jmb.2006.03.039  1
2006 Cho W, Stahelin RV. In vitro and Cellular Membrane-binding Mechanisms of Membrane-targeting Domains Protein-Lipid Interactions: From Membrane Domains to Cellular Networks. 367-401. DOI: 10.1002/3527606769.ch15  1
2005 Stahelin RV, Hwang JH, Kim JH, Park ZY, Johnson KR, Obeid LM, Cho W. The mechanism of membrane targeting of human sphingosine kinase 1. The Journal of Biological Chemistry. 280: 43030-8. PMID 16243846 DOI: 10.1074/Jbc.M507574200  1
2005 Stahelin RV, Wang J, Blatner NR, Rafter JD, Murray D, Cho W. The origin of C1A-C2 interdomain interactions in protein kinase Calpha. The Journal of Biological Chemistry. 280: 36452-63. PMID 16079140 DOI: 10.1074/Jbc.M506224200  1
2005 Málková S, Long F, Stahelin RV, Pingali SV, Murray D, Cho W, Schlossman ML. X-ray reflectivity studies of cPLA2{alpha}-C2 domains adsorbed onto Langmuir monolayers of SOPC. Biophysical Journal. 89: 1861-73. PMID 15994899 DOI: 10.1529/Biophysj.105.061515  1
2005 Cho W, Stahelin RV. Membrane-protein interactions in cell signaling and membrane trafficking. Annual Review of Biophysics and Biomolecular Structure. 34: 119-51. PMID 15869386 DOI: 10.1146/Annurev.Biophys.33.110502.133337  1
2005 Stahelin RV, Digman MA, Medkova M, Ananthanarayanan B, Melowic HR, Rafter JD, Cho W. Diacylglycerol-induced membrane targeting and activation of protein kinase Cepsilon: mechanistic differences between protein kinases Cdelta and Cepsilon. The Journal of Biological Chemistry. 280: 19784-93. PMID 15769752 DOI: 10.1074/Jbc.M411285200  1
2005 Subramanian P, Stahelin RV, Szulc Z, Bielawska A, Cho W, Chalfant CE. Ceramide 1-phosphate acts as a positive allosteric activator of group IVA cytosolic phospholipase A2 alpha and enhances the interaction of the enzyme with phosphatidylcholine. The Journal of Biological Chemistry. 280: 17601-7. PMID 15743759 DOI: 10.1074/Jbc.M414173200  1
2004 Stahelin RV, Ananthanarayanan B, Blatner NR, Singh S, Bruzik KS, Murray D, Cho W. Mechanism of membrane binding of the phospholipase D1 PX domain. The Journal of Biological Chemistry. 279: 54918-26. PMID 15475361 DOI: 10.1074/Jbc.M407798200  1
2004 Blatner NR, Stahelin RV, Diraviyam K, Hawkins PT, Hong W, Murray D, Cho W. The molecular basis of the differential subcellular localization of FYVE domains. The Journal of Biological Chemistry. 279: 53818-27. PMID 15452113 DOI: 10.1074/Jbc.M408408200  1
2004 Stahelin RV, Digman MA, Medkova M, Ananthanarayanan B, Rafter JD, Melowic HR, Cho W. Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta. The Journal of Biological Chemistry. 279: 29501-12. PMID 15105418 DOI: 10.1074/jbc.M403191200  1
2003 Ananthanarayanan B, Stahelin RV, Digman MA, Cho W. Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains. The Journal of Biological Chemistry. 278: 46886-94. PMID 12954613 DOI: 10.1074/Jbc.M307853200  1
2003 Cho W, Digman M, Ananthanarayanan B, Stahelin RV. Bacterial expression and purification of C1 and C2 domains of protein kinase C isoforms. Methods in Molecular Biology (Clifton, N.J.). 233: 291-8. PMID 12840516 DOI: 10.1385/1-59259-397-6:291  1
2003 Stahelin RV, Long F, Peter BJ, Murray D, De Camilli P, McMahon HT, Cho W. Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains. The Journal of Biological Chemistry. 278: 28993-9. PMID 12740367 DOI: 10.1074/Jbc.M302865200  1
2003 Diraviyam K, Stahelin RV, Cho W, Murray D. Computer modeling of the membrane interaction of FYVE domains. Journal of Molecular Biology. 328: 721-36. PMID 12706728 DOI: 10.1016/S0022-2836(03)00325-5  1
2003 Stahelin RV, Burian A, Bruzik KS, Murray D, Cho W. Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox. The Journal of Biological Chemistry. 278: 14469-79. PMID 12556460 DOI: 10.1074/Jbc.M212579200  1
2003 Stahelin RV, Rafter JD, Das S, Cho W. The molecular basis of differential subcellular localization of C2 domains of protein kinase C-alpha and group IVa cytosolic phospholipase A2. The Journal of Biological Chemistry. 278: 12452-60. PMID 12531893 DOI: 10.1074/Jbc.M212864200  1
2003 Stahelin RV, Forslund RE, Wink DJ, Cho W. Development of a biochemistry laboratory course with a project-oriented goal Biochemistry and Molecular Biology Education. 31: 106-112. DOI: 10.1002/Bmb.2003.494031020182  1
2002 Karathanassis D, Stahelin RV, Bravo J, Perisic O, Pacold CM, Cho W, Williams RL. Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction. The Embo Journal. 21: 5057-68. PMID 12356722 DOI: 10.1093/Emboj/Cdf519  1
2002 Stahelin RV, Long F, Diraviyam K, Bruzik KS, Murray D, Cho W. Phosphatidylinositol 3-phosphate induces the membrane penetration of the FYVE domains of Vps27p and Hrs. The Journal of Biological Chemistry. 277: 26379-88. PMID 12006563 DOI: 10.1074/Jbc.M201106200  1
2001 Stahelin RV, Cho W. Roles of calcium ions in the membrane binding of C2 domains Biochemical Journal. 359: 679-685. PMID 11672443 DOI: 10.1042/0264-6021:3590679  1
2001 Cho W, Bittova L, Stahelin RV. Membrane binding assays for peripheral proteins. Analytical Biochemistry. 296: 153-61. PMID 11554709 DOI: 10.1006/Abio.2001.5225  1
2001 Stahelin RV, Cho W. Differential roles of ionic, aliphatic, and aromatic residues in membrane - Protein interactions: A surface plasmon resonance study on phospholipases A2 Biochemistry. 40: 4672-4678. PMID 11294634 DOI: 10.1021/Bi0020325  1
2001 Bittova L, Stahelin RV, Cho W. Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity. The Journal of Biological Chemistry. 276: 4218-26. PMID 11029472 DOI: 10.1074/Jbc.M008491200  1
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