Steven O. Mansoorabadi, Ph.D. - Publications

2006 University of Wisconsin, Madison, Madison, WI 
Biochemistry, General Biophysics

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.


Year Citation  Score
2017 Pierce E, Mansoorabadi SO, Can M, Reed GH, Ragsdale SW. Properties of intermediates in the catalytic cycle of oxalate oxidoreductase and its suicide inactivation by pyruvate. Biochemistry. PMID 28514140 DOI: 10.1021/acs.biochem.7b00222  1
2016 Ngo PD, Mansoorabadi SO, Frey PA. Serine Protease Catalysis: A Computational Study of Tetrahedral Intermediates and Inhibitory Adducts. The Journal of Physical Chemistry. B. PMID 27387593 DOI: 10.1021/acs.jpcb.6b04089  1
2014 Mansoorabadi SO, Wu M, Tao Z, Gao P, Pingali SV, Guo L, Liu HW. Conformational activation of poly(ADP-ribose) polymerase-1 upon DNA binding revealed by small-angle X-ray scattering. Biochemistry. 53: 1779-88. PMID 24588584 DOI: 10.1021/bi401439n  1
2013 Kim HJ, McCarty RM, Ogasawara Y, Liu YN, Mansoorabadi SO, LeVieux J, Liu HW. GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme. Journal of the American Chemical Society. 135: 8093-6. PMID 23679096 DOI: 10.1021/ja312641f  1
2013 Chang WC, Mansoorabadi SO, Liu HW. Reaction of HppE with substrate analogues: evidence for carbon-phosphorus bond cleavage by a carbocation rearrangement. Journal of the American Chemical Society. 135: 8153-6. PMID 23672451 DOI: 10.1021/ja403441x  1
2013 Chang WC, Dey M, Liu P, Mansoorabadi SO, Moon SJ, Zhao ZK, Drennan CL, Liu HW. Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reaction. Nature. 496: 114-8. PMID 23552950 DOI: 10.1038/nature11998  1
2012 Huang H, Chang WC, Pai PJ, Romo A, Mansoorabadi SO, Russell DH, Liu HW. Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analogues. Journal of the American Chemical Society. 134: 16171-4. PMID 23006053 DOI: 10.1021/ja3078126  1
2012 Choi SH, Mansoorabadi SO, Liu YN, Chien TC, Liu HW. Analysis of UDP-D-apiose/UDP-D-xylose synthase-catalyzed conversion of UDP-D-apiose phosphonate to UDP-D-xylose phosphonate: implications for a retroaldol-aldol mechanism. Journal of the American Chemical Society. 134: 13946-9. PMID 22830643 DOI: 10.1021/ja305322x  1
2012 Reed GH, Ragsdale SW, Mansoorabadi SO. Radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases. Biochimica Et Biophysica Acta. 1824: 1291-8. PMID 22178227 DOI: 10.1016/j.bbapap.2011.11.010  1
2012 Calveras J, Thibodeaux CJ, Mansoorabadi SO, Liu HW. Stereochemical studies of the type II isopentenyl diphosphate-dimethylallyl diphosphate isomerase implicate the FMN coenzyme in substrate protonation. Chembiochem : a European Journal of Chemical Biology. 13: 42-6. PMID 22135039 DOI: 10.1002/cbic.201100694  1
2011 Ruszczycky MW, Choi SH, Mansoorabadi SO, Liu HW. Mechanistic studies of the radical S-adenosyl-L-methionine enzyme DesII: EPR characterization of a radical intermediate generated during its catalyzed dehydrogenation of TDP-D-quinovose. Journal of the American Chemical Society. 133: 7292-5. PMID 21513273 DOI: 10.1021/ja201212f  1
2009 Tang KH, Mansoorabadi SO, Reed GH, Frey PA. Radical triplets and suicide inhibition in reactions of 4-thia-D- and 4-thia-L-lysine with lysine 5,6-aminomutase. Biochemistry. 48: 8151-60. PMID 19634897 DOI: 10.1021/bi900828f  1
2009 Munos JW, Pu X, Mansoorabadi SO, Kim HJ, Liu HW. A secondary kinetic isotope effect study of the 1-deoxy-D-xylulose-5-phosphate reductoisomerase-catalyzed reaction: evidence for a retroaldol-aldol rearrangement. Journal of the American Chemical Society. 131: 2048-9. PMID 19159292 DOI: 10.1021/ja807987h  1
2009 Martinez-Gomez NC, Poyner RR, Mansoorabadi SO, Reed GH, Downs DM. Reaction of AdoMet with ThiC generates a backbone free radical. Biochemistry. 48: 217-9. PMID 19113839 DOI: 10.1021/bi802154j  1
2008 Munos JW, Moon SJ, Mansoorabadi SO, Chang W, Hong L, Yan F, Liu A, Liu HW. Purification and characterization of the epoxidase catalyzing the formation of fosfomycin from Pseudomonas syringae. Biochemistry. 47: 8726-35. PMID 18656958 DOI: 10.1021/bi800877v  1
2008 Thibodeaux CJ, Mansoorabadi SO, Kittleman W, Chang WC, Liu HW. Evidence for the involvement of acid/base chemistry in the reaction catalyzed by the type II isopentenyl diphosphate/dimethylallyl diphosphate isomerase from Staphylococcus aureus. Biochemistry. 47: 2547-58. PMID 18229948 DOI: 10.1021/bi701467g  1
2007 Mansoorabadi SO, Thibodeaux CJ, Liu HW. The diverse roles of flavin coenzymes--nature's most versatile thespians. The Journal of Organic Chemistry. 72: 6329-42. PMID 17580897 DOI: 10.1021/jo0703092  1
2006 Mansoorabadi SO, Magnusson OT, Poyner RR, Frey PA, Reed GH. Analysis of the Cob(II)alamin-5'-deoxy-3',4'-anhydroadenosyl radical triplet spin system in the active site of diol dehydrase. Biochemistry. 45: 14362-70. PMID 17128975 DOI: 10.1021/bi061586q  1
2006 Behshad E, Ruzicka FJ, Mansoorabadi SO, Chen D, Reed GH, Frey PA. Enantiomeric free radicals and enzymatic control of stereochemistry in a radical mechanism: the case of lysine 2,3-aminomutases. Biochemistry. 45: 12639-46. PMID 17042480 DOI: 10.1021/bi061328t  1
2006 Yoon M, Patwardhan A, Qiao C, Mansoorabadi SO, Menefee AL, Reed GH, Marsh EN. Reaction of adenosylcobalamin-dependent glutamate mutase with 2-thiolglutarate. Biochemistry. 45: 11650-7. PMID 16981724 DOI: 10.1021/bi061067n  1
2006 Mansoorabadi SO, Seravalli J, Furdui C, Krymov V, Gerfen GJ, Begley TP, Melnick J, Ragsdale SW, Reed GH. EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase. Biochemistry. 45: 7122-31. PMID 16752902 DOI: 10.1021/bi0602516  1
2006 Astashkin AV, Seravalli J, Mansoorabadi SO, Reed GH, Ragsdale SW. Pulsed electron paramagnetic resonance experiments identify the paramagnetic intermediates in the pyruvate ferredoxin oxidoreductase catalytic cycle. Journal of the American Chemical Society. 128: 3888-9. PMID 16551078 DOI: 10.1021/ja0585275  1
2006 Sims PA, Menefee AL, Larsen TM, Mansoorabadi SO, Reed GH. Structure and catalytic properties of an engineered heterodimer of enolase composed of one active and one inactive subunit. Journal of Molecular Biology. 355: 422-31. PMID 16309698 DOI: 10.1016/j.jmb.2005.10.050  1
2005 Mansoorabadi SO, Padmakumar R, Fazliddinova N, Vlasie M, Banerjee R, Reed GH. Characterization of a succinyl-CoA radical-cob(II)alamin spin triplet intermediate in the reaction catalyzed by adenosylcobalamin-dependent methylmalonyl-CoA mutase. Biochemistry. 44: 3153-8. PMID 15736925 DOI: 10.1021/bi0482102  1
2003 Reed GH, Mansoorabadi SO. The positions of radical intermediates in the active sites of adenosylcobalamin-dependent enzymes. Current Opinion in Structural Biology. 13: 716-21. PMID 14675550 DOI: 10.1016/  1
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