| Year |
Citation |
Score |
| 2024 |
Neja S, Dashwood WM, Dashwood RH, Rajendran P. Histone Acyl Code in Precision Oncology: Mechanistic Insights from Dietary and Metabolic Factors. Nutrients. 16. PMID 38337680 DOI: 10.3390/nu16030396 |
0.349 |
|
| 2023 |
Zhang S, Kapoor S, Tripathi C, Perez JT, Mohan N, Dashwood WM, Zhang K, Rajendran P, Dashwood R. Targeting ACE2-BRD4 crosstalk in colorectal cancer and the deregulation of DNA repair and apoptosis. Npj Precision Oncology. 7: 20. PMID 36801948 DOI: 10.1038/s41698-023-00361-4 |
0.317 |
|
| 2022 |
Kapoor S, Damiani E, Wang S, Dharmanand R, Tripathi C, Tovar Perez JE, Dashwood WM, Rajendran P, Dashwood RH. BRD9 Inhibition by Natural Polyphenols Targets DNA Damage/Repair and Apoptosis in Human Colon Cancer Cells. Nutrients. 14. PMID 36297001 DOI: 10.3390/nu14204317 |
0.4 |
|
| 2022 |
Chen YS, Li J, Neja S, Kapoor S, Tovar Perez JE, Tripathi C, Menon R, Jayaraman A, Lee K, Dashwood WM, Wang S, Zhang K, Kobayashi K, Rajendran P, Dashwood R. Metabolomics of Acute vs. Chronic Spinach Intake in an Apc-Mutant Genetic Background: Linoleate and Butanoate Metabolites Targeting HDAC Activity and IFN-γ Signaling. Cells. 11. PMID 35159382 DOI: 10.3390/cells11030573 |
0.312 |
|
| 2021 |
Kapoor S, Gustafson T, Zhang M, Chen YS, Li J, Nguyen N, Perez JET, Dashwood WM, Rajendran P, Dashwood RH. Deacetylase Plus Bromodomain Inhibition Downregulates ERCC2 and Suppresses the Growth of Metastatic Colon Cancer Cells. Cancers. 13. PMID 33809839 DOI: 10.3390/cancers13061438 |
0.395 |
|
| 2021 |
Dashwood RH. Cancer interception by interceptor molecules: mechanistic, preclinical and human translational studies with chlorophylls. Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society. 43: 8. PMID 33676582 DOI: 10.1186/s41021-021-00180-8 |
0.308 |
|
| 2020 |
Damiani E, Duran MN, Mohan N, Rajendran P, Dashwood RH. Targeting Epigenetic 'Readers' with Natural Compounds for Cancer Interception. Journal of Cancer Prevention. 25: 189-203. PMID 33409252 DOI: 10.15430/JCP.2020.25.4.189 |
0.351 |
|
| 2020 |
Johnson GS, Rajendran P, Dashwood RH. CCAR1 and CCAR2 as gene chameleons with antagonistic duality: Preclinical, human translational, and mechanistic basis. Cancer Science. 111: 3416-3425. PMID 33403784 DOI: 10.1111/Cas.14579 |
0.45 |
|
| 2020 |
Davis JS, Kanikarla-Marie P, Gagea M, Yu PL, Fang D, Sebastian M, Yang P, Hawk E, Dashwood R, Lichtenberger LM, Menter D, Kopetz S. Sulindac plus a phospholipid is effective for polyp reduction and safer than sulindac alone in a mouse model of colorectal cancer development. Bmc Cancer. 20: 871. PMID 32912193 DOI: 10.1186/S12885-020-07311-4 |
0.389 |
|
| 2020 |
Bhattacharjee S, Li J, Dashwood RH. Emerging crosstalk between long non-coding RNAs and Nrf2 signaling. Cancer Letters. PMID 32717274 DOI: 10.1016/J.Canlet.2020.07.011 |
0.324 |
|
| 2020 |
Rajendran P, Damiani E, Wang S, Dashwood W, Dashwood RH. Abstract 3477: Dietary polyphenols as epigenetic ‘reader' inhibitors Cancer Research. 80: 3477-3477. DOI: 10.1158/1538-7445.Am2020-3477 |
0.486 |
|
| 2019 |
Zhang Z, Garzotto M, Davis EW, Mori M, Stoller WA, Farris PE, Wong CP, Beaver LM, Thomas GV, Williams DE, Dashwood RH, Hendrix DA, Ho E, Shannon J. Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial. Nutrition and Cancer. 1-14. PMID 31155953 DOI: 10.1080/01635581.2019.1619783 |
0.376 |
|
| 2019 |
Rajendran P, Johnson GS, Li L, Chen YS, Dashwood WM, Nguyen N, Ulusan AM, Ertem FU, Zhang M, Li J, Sun D, Huang Y, Wang S, Leung HE, Lieberman D, ... ... Dashwood RH, et al. Acetylation of CCAR2 establishes a BET/BRD9 acetyl switch in response to combined deacetylase and bromodomain inhibition. Cancer Research. PMID 30643017 DOI: 10.1158/0008-5472.Can-18-2003 |
0.517 |
|
| 2019 |
Ulusan A, Rajendran P, Dashwood W, Mohammed A, Sei S, Brown PH, Vilar-Sanchez E, Dashwood RH. Abstract 5074: Optimizing erlotinib plus sulindac dosing regimens in a preclinical model of FAP Cancer Research. 79: 5074-5074. DOI: 10.1158/1538-7445.Am2019-5074 |
0.372 |
|
| 2019 |
Johnson GS, Rajendran P, Li L, Chen Y, Dashwood WM, Nguyen N, Ulusan AM, Ertem F, Zhang M, Sun D, Huang Y, Wang S, Leung HE, Lieberman D, Beaver LM, ... ... Dashwood RH, et al. Abstract 2614: CCAR2 acetylation establishes a BET/BRD9 acetyl switch in response to combined deacetylase and bromodomain inhibition Cancer Research. 79: 2614-2614. DOI: 10.1158/1538-7445.Am2019-2614 |
0.521 |
|
| 2018 |
Zhang J, Tan P, Guo L, Gong J, Ma J, Li J, Lee M, Fang S, Jing J, Johnson G, Sun D, Cao WM, Dashwood R, Han L, Zhou Y, et al. p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance. Oncogene. PMID 30390073 DOI: 10.1038/S41388-018-0524-5 |
0.402 |
|
| 2018 |
Beaver LM, Lӧhr CV, Clarke JD, Glasser ST, Watson GW, Wong CP, Zhang Z, Williams DE, Dashwood RH, Shannon J, Thuillier P, Ho E. Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice. Current Developments in Nutrition. 2: nzy002. PMID 30019025 DOI: 10.1093/cdn/nzy002 |
0.328 |
|
| 2018 |
Reddy DS, Wu X, Golub VM, Dashwood WM, Dashwood RH. Measuring Histone Deacetylase Inhibition in the Brain. Current Protocols in Pharmacology. e41. PMID 29927058 DOI: 10.1002/Cpph.41 |
0.438 |
|
| 2018 |
Okonkwo A, Mitra J, Johnson GS, Li L, Dashwood WM, Hegde M, Yue C, Dashwood RH, Rajendran P. Heterocyclic Analogs of Sulforaphane Trigger DNA Damage and Impede DNA Repair in Colon Cancer Cells: Interplay of HATs and HDACs. Molecular Nutrition & Food Research. e1800228. PMID 29924908 DOI: 10.1002/Mnfr.201800228 |
0.395 |
|
| 2017 |
Kumar R, Herold JL, Schady D, Davis J, Kopetz S, Martinez-Moczygemba M, Murray BE, Han F, Li Y, Callaway E, Chapkin RS, Dashwood WM, Dashwood RH, Berry T, Mackenzie C, et al. Streptococcus gallolyticus subsp. gallolyticus promotes colorectal tumor development. Plos Pathogens. 13: e1006440. PMID 28704539 DOI: 10.1371/journal.ppat.1006440 |
0.308 |
|
| 2017 |
Palomera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E. The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells. The Journal of Nutritional Biochemistry. 47: 113-119. PMID 28582660 DOI: 10.1016/J.Jnutbio.2017.05.005 |
0.385 |
|
| 2017 |
Chen YS, Wang R, Dashwood WM, Löhr CV, Williams DE, Ho E, Mertens-Talcott S, Dashwood RH. A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat. Archives of Toxicology. PMID 28289824 DOI: 10.1007/S00204-017-1945-6 |
0.314 |
|
| 2017 |
Wang R, Chen YS, Dashwood WM, Li Q, Löhr CV, Fischer K, Ho E, Williams DE, Dashwood RH. Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors. Molecular Carcinogenesis. PMID 28218467 DOI: 10.1002/Mc.22630 |
0.384 |
|
| 2017 |
Beaver LM, Kuintzle R, Buchanan A, Wiley MW, Glasser ST, Wong CP, Johnson GS, Chang JH, Löhr CV, Williams DE, Dashwood RH, Hendrix DA, Ho E. Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer. The Journal of Nutritional Biochemistry. 42: 72-83. PMID 28131897 DOI: 10.1016/J.Jnutbio.2017.01.001 |
0.346 |
|
| 2017 |
Chen Y, Wang R, Dashwood W, Löhr C, Williams DE, Ho E, Mertens-Talcott S, Dashwood RH. Abstract 4428: A miRNA signature linked to human environmental risk defined from carcinogen-induced and genetically-driven colon carcinogenesis models Cancer Research. 77: 4428-4428. DOI: 10.1158/1538-7445.Am2017-4428 |
0.315 |
|
| 2017 |
Ertem FU, Zhang W, Chang K, Dashwood W, Rajendran P, Sun D, Abudayyeh A, Abdulrahim M, Vilar E, Dashwood RH. Abstract 2229: Prevention by tolfenamic acid and characterization of the molecular targets in Pirc and FAP colorectal adenomas Cancer Research. 77: 2229-2229. DOI: 10.1158/1538-7445.Am2017-2229 |
0.406 |
|
| 2016 |
Johnson GS, Li J, Beaver LM, Dashwood WM, Sun D, Rajendran P, Williams DE, Ho E, Dashwood RH. A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a co-activator of NQO1 in sulforaphane-treated colon cancer cells. Molecular Nutrition & Food Research. PMID 27860235 DOI: 10.1002/Mnfr.201600769 |
0.42 |
|
| 2016 |
Ertem FU, Zhang W, Chang K, Mohaiza Dashwood W, Rajendran P, Sun D, Abudayyeh A, Vilar E, Abdelrahim M, Dashwood RH. Oncogenic targets Mmp7, S100a9, Nppb and Aldh1a3 from transcriptome profiling of FAP and Pirc adenomas are downregulated in response to tumor suppression by Clotam. International Journal of Cancer. PMID 27706811 DOI: 10.1002/Ijc.30458 |
0.386 |
|
| 2016 |
Wang R, Kang Y, Löhr CV, Fischer KA, Bradford CS, Johnson G, Dashwood WM, Williams DE, Ho E, Dashwood RH. Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer. Cancer Letters. PMID 27539959 DOI: 10.1016/J.Canlet.2016.08.008 |
0.467 |
|
| 2016 |
Kim H, Banerjee N, Ivanov I, Pfent CM, Prudhomme KR, Bisson WH, Dashwood RH, Talcott ST, Mertens-Talcott SU. Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis. Molecular Nutrition & Food Research. PMID 27028006 DOI: 10.1002/Mnfr.201501008 |
0.3 |
|
| 2016 |
Ertem FU, Dashwood W, Rajendran P, Raju G, Rashid A, Dashwood R. Abstract 839: Novel polypectomy system in a preclinical model of colon cancer Cancer Research. 76: 839-839. DOI: 10.1158/1538-7445.Am2016-839 |
0.359 |
|
| 2015 |
Watson GW, Wickramasekara S, Fang Y, Maier CS, Williams DE, Dashwood RH, Perez VI, Ho E. HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells. Experimental Biology and Medicine (Maywood, N.J.). PMID 26643866 DOI: 10.1177/1535370215618518 |
0.508 |
|
| 2015 |
Rajendran P, Dashwood WM, Li L, Kang Y, Kim E, Johnson G, Fischer KA, Löhr CV, Williams DE, Ho E, Yamamoto M, Lieberman DA, Dashwood RH. Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon. Clinical Epigenetics. 7: 102. PMID 26388957 DOI: 10.1186/S13148-015-0132-Y |
0.443 |
|
| 2015 |
Kim E, Bisson WH, Löhr CV, Williams DE, Ho E, Dashwood RH, Rajendran P. Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors. Current Topics in Medicinal Chemistry. PMID 26303421 DOI: 10.2174/1568026615666150825125857 |
0.486 |
|
| 2015 |
Watson GW, Wickramasekara S, Fang Y, Palomera-Sanchez Z, Maier CS, Williams DE, Dashwood RH, Perez VI, Ho E. Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells. Molecular Nutrition & Food Research. PMID 26108801 DOI: 10.1002/Mnfr.201500283 |
0.374 |
|
| 2015 |
Atwell LL, Beaver LM, Shannon J, Williams DE, Dashwood RH, Ho E. Epigenetic Regulation by Sulforaphane: Opportunities for Breast and Prostate Cancer Chemoprevention. Current Pharmacology Reports. 1: 102-111. PMID 26042194 DOI: 10.1007/S40495-014-0002-X |
0.483 |
|
| 2015 |
Dashwood RH. Abstract CN12-02: Dietary HDAC inhibitors: Prevention or therapy? Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-Cn12-02 |
0.506 |
|
| 2014 |
Watson GW, Wickramasekara S, Palomera-Sanchez Z, Black C, Maier CS, Williams DE, Dashwood RH, Ho E. SUV39H1/H3K9me3 attenuates sulforaphane-induced apoptotic signaling in PC3 prostate cancer cells. Oncogenesis. 3: e131. PMID 25486523 DOI: 10.1038/oncsis.2014.47 |
0.368 |
|
| 2014 |
Kang Y, Nian H, Rajendran P, Kim E, Dashwood WM, Pinto JT, Boardman LA, Thibodeau SN, Limburg PJ, Löhr CV, Bisson WH, Williams DE, Ho E, Dashwood RH. HDAC8 and STAT3 repress BMF gene activity in colon cancer cells. Cell Death & Disease. 5: e1476. PMID 25321483 DOI: 10.1038/Cddis.2014.422 |
0.629 |
|
| 2014 |
Beaver LM, Buchanan A, Sokolowski EI, Riscoe AN, Wong CP, Chang JH, Löhr CV, Williams DE, Dashwood RH, Ho E. Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention. Molecular Nutrition & Food Research. 58: 2001-13. PMID 25044704 DOI: 10.1002/Mnfr.201400269 |
0.424 |
|
| 2014 |
Wong CP, Hsu A, Buchanan A, Palomera-Sanchez Z, Beaver LM, Houseman EA, Williams DE, Dashwood RH, Ho E. Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells. Plos One. 9: e86787. PMID 24466240 DOI: 10.1371/Journal.Pone.0086787 |
0.433 |
|
| 2013 |
Cerella C, Michiels C, Dashwood RH, Surh YJ, Diederich M. Metabolism and cancer: old and new players. International Journal of Cell Biology. 2013: 293201. PMID 23864859 DOI: 10.1155/2013/293201 |
0.438 |
|
| 2013 |
Kaur P, Shorey LE, Ho E, Dashwood RH, Williams DE. The epigenome as a potential mediator of cancer and disease prevention in prenatal development. Nutrition Reviews. 71: 441-57. PMID 23815143 DOI: 10.1111/Nure.12030 |
0.375 |
|
| 2013 |
Rajendran P, Kidane AI, Yu TW, Dashwood WM, Bisson WH, Löhr CV, Ho E, Williams DE, Dashwood RH. HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. Epigenetics : Official Journal of the Dna Methylation Society. 8: 612-23. PMID 23770684 DOI: 10.4161/Epi.24710 |
0.5 |
|
| 2013 |
Shorey LE, Madeen EP, Atwell LL, Ho E, Löhr CV, Pereira CB, Dashwood RH, Williams DE. Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane. Toxicology and Applied Pharmacology. 270: 60-9. PMID 23566957 DOI: 10.1016/J.Taap.2013.02.016 |
0.367 |
|
| 2013 |
Wang R, Löhr CV, Fischer K, Dashwood WM, Greenwood JA, Ho E, Williams DE, Ashktorab H, Dashwood MR, Dashwood RH. Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer. International Journal of Cancer. Journal International Du Cancer. 132: 1004-12. PMID 22865632 DOI: 10.1002/Ijc.27762 |
0.389 |
|
| 2012 |
Romagnolo DF, Dashwood R, Stover PJ, Waterland RA, Ziegler TR. Nutritional regulation of epigenetic changes. Advances in Nutrition (Bethesda, Md.). 3: 749-50. PMID 22983864 DOI: 10.3945/An.112.002675 |
0.337 |
|
| 2012 |
Beaver LM, Yu TW, Sokolowski EI, Williams DE, Dashwood RH, Ho E. 3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells. Toxicology and Applied Pharmacology. 263: 345-51. PMID 22800507 DOI: 10.1016/J.Taap.2012.07.007 |
0.513 |
|
| 2012 |
Parasramka MA, Dashwood WM, Wang R, Abdelli A, Bailey GS, Williams DE, Ho E, Dashwood RH. MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach. Molecular Nutrition & Food Research. 56: 1259-69. PMID 22641368 DOI: 10.1002/Mnfr.201200117 |
0.305 |
|
| 2012 |
Shorey LE, Hagman AM, Williams DE, Ho E, Dashwood RH, Benninghoff AD. 3,3'-Diindolylmethane induces G1 arrest and apoptosis in human acute T-cell lymphoblastic leukemia cells. Plos One. 7: e34975. PMID 22514694 DOI: 10.1371/Journal.Pone.0034975 |
0.373 |
|
| 2012 |
McQuistan TJ, Simonich MT, Pratt MM, Pereira CB, Hendricks JD, Dashwood RH, Williams DE, Bailey GS. Cancer chemoprevention by dietary chlorophylls: a 12,000-animal dose-dose matrix biomarker and tumor study. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 50: 341-52. PMID 22079312 DOI: 10.1016/J.Fct.2011.10.065 |
0.33 |
|
| 2012 |
Lee SH, Richardson RL, Dashwood RH, Baek SJ. Capsaicin represses transcriptional activity of β-catenin in human colorectal cancer cells. The Journal of Nutritional Biochemistry. 23: 646-55. PMID 21764279 DOI: 10.1016/J.Jnutbio.2011.03.009 |
0.395 |
|
| 2012 |
Parasramka MA, Ho E, Williams DE, Dashwood RH. MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals. Molecular Carcinogenesis. 51: 213-30. PMID 21739482 DOI: 10.1002/Mc.20822 |
0.33 |
|
| 2012 |
Dashwood R. Chlorophylls as anticarcinogens (review). International Journal of Oncology. 10: 721-7. PMID 21533436 DOI: 10.3892/ijo.10.4.721 |
0.319 |
|
| 2012 |
Rajendran P, kidane AI, Yu T, Dashwood W, Ho E, Williams DE, Dashwood RH. Abstract LB-184: Differential effects of sulforaphane and related isothiocyanates on HDAC turnover and the DNA damage response in colon cancer cells Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-184 |
0.463 |
|
| 2012 |
Shorey LE, Kaur P, Rosato C, Houseman EA, Ho E, Dashwood RH, Benninghoff AD, Williams DE. Abstract 5430: Analysis of genome-wide DNA methylation in CCRF-CEM cells confirms hypermethylation at reported epigenetic markers of T-cell lymphoblastic leukemia and identifies novel therapeutic targets with reduced methylation upon treatment with dietary indoles Cancer Research. 72: 5430-5430. DOI: 10.1158/1538-7445.Am2012-5430 |
0.335 |
|
| 2011 |
Ho E, Beaver LM, Williams DE, Dashwood RH. Dietary factors and epigenetic regulation for prostate cancer prevention. Advances in Nutrition (Bethesda, Md.). 2: 497-510. PMID 22332092 DOI: 10.3945/An.111.001032 |
0.466 |
|
| 2011 |
Hsu A, Wong CP, Yu Z, Williams DE, Dashwood RH, Ho E. Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells. Clinical Epigenetics. 3: 3. PMID 22303414 DOI: 10.1186/1868-7083-3-3 |
0.441 |
|
| 2011 |
Rajendran P, Ho E, Williams DE, Dashwood RH. Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clinical Epigenetics. 3: 4. PMID 22247744 DOI: 10.1186/1868-7083-3-4 |
0.46 |
|
| 2011 |
Li Q, Luo C, Löhr CV, Dashwood RH. Activator protein-2α functions as a master regulator of multiple transcription factors in the mouse liver. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 41: 776-83. PMID 21682828 DOI: 10.1111/J.1872-034X.2011.00827.X |
0.307 |
|
| 2011 |
Rajendran P, Delage B, Dashwood WM, Yu TW, Wuth B, Williams DE, Ho E, Dashwood RH. Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly. Molecular Cancer. 10: 68. PMID 21624135 DOI: 10.1186/1476-4598-10-68 |
0.538 |
|
| 2011 |
Rajendran P, Williams DE, Ho E, Dashwood RH. Metabolism as a key to histone deacetylase inhibition. Critical Reviews in Biochemistry and Molecular Biology. 46: 181-99. PMID 21599534 DOI: 10.3109/10409238.2011.557713 |
0.472 |
|
| 2011 |
Clarke JD, Hsu A, Yu Z, Dashwood RH, Ho E. Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells. Molecular Nutrition & Food Research. 55: 999-1009. PMID 21374800 DOI: 10.1002/Mnfr.201000547 |
0.502 |
|
| 2011 |
Wang R, Dashwood RH. Endothelins and their receptors in cancer: identification of therapeutic targets. Pharmacological Research. 63: 519-24. PMID 21251982 DOI: 10.1016/J.Phrs.2011.01.002 |
0.399 |
|
| 2011 |
Wang R, Dashwood WM, Nian H, Löhr CV, Fischer KA, Tsuchiya N, Nakagama H, Ashktorab H, Dashwood RH. NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). International Journal of Cancer. Journal International Du Cancer. 128: 2581-90. PMID 20715105 DOI: 10.1002/Ijc.25610 |
0.642 |
|
| 2010 |
Ho E, Dashwood RH. Dietary manipulation of histone structure and function. Journal of Nutrigenetics and Nutrigenomics. 3: 231-8. PMID 21474954 DOI: 10.1159/000324359 |
0.538 |
|
| 2010 |
Larsen CA, Dashwood RH, Bisson WH. Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance. Pharmacological Research. 62: 457-64. PMID 20691268 DOI: 10.1016/J.Phrs.2010.07.010 |
0.697 |
|
| 2010 |
Larsen CA, Dashwood RH. (-)-Epigallocatechin-3-gallate inhibits Met signaling, proliferation, and invasiveness in human colon cancer cells. Archives of Biochemistry and Biophysics. 501: 52-7. PMID 20361925 DOI: 10.1016/J.Abb.2010.03.017 |
0.71 |
|
| 2010 |
Kwon IK, Wang R, Thangaraju M, Shuang H, Liu K, Dashwood R, Dulin N, Ganapathy V, Browning DD. PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4. Oncogene. 29: 3423-34. PMID 20348951 DOI: 10.1038/Onc.2010.91 |
0.441 |
|
| 2009 |
Larsen CA, Bisson WH, Dashwood RH. Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies. Journal of Medicinal Chemistry. 52: 6543-5. PMID 19839593 DOI: 10.1021/Jm901330E |
0.689 |
|
| 2009 |
Ho E, Clarke JD, Dashwood RH. Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention. The Journal of Nutrition. 139: 2393-6. PMID 19812222 DOI: 10.3945/Jn.109.113332 |
0.541 |
|
| 2009 |
Larsen CA, Dashwood RH. Suppression of Met activation in human colon cancer cells treated with (-)-epigallocatechin-3-gallate: minor role of hydrogen peroxide. Biochemical and Biophysical Research Communications. 389: 527-30. PMID 19744467 DOI: 10.1016/J.Bbrc.2009.09.019 |
0.681 |
|
| 2009 |
Chimploy K, DÃaz GD, Li Q, Carter O, Dashwood WM, Mathews CK, Williams DE, Bailey GS, Dashwood RH. E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin. International Journal of Cancer. Journal International Du Cancer. 125: 2086-94. PMID 19585502 DOI: 10.1002/Ijc.24559 |
0.358 |
|
| 2009 |
Lee JI, Nian H, Cooper AJ, Sinha R, Dai J, Bisson WH, Dashwood RH, Pinto JT. Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells. Cancer Prevention Research (Philadelphia, Pa.). 2: 683-93. PMID 19584079 DOI: 10.1158/1940-6207.Capr-09-0047 |
0.645 |
|
| 2009 |
Nian H, Bisson WH, Dashwood WM, Pinto JT, Dashwood RH. Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells. Carcinogenesis. 30: 1416-23. PMID 19528666 DOI: 10.1093/Carcin/Bgp147 |
0.685 |
|
| 2009 |
Li Q, Löhr CV, Dashwood RH. Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse. Cancer Letters. 283: 36-42. PMID 19376641 DOI: 10.1016/J.Canlet.2009.03.026 |
0.367 |
|
| 2009 |
Nian H, Delage B, Ho E, Dashwood RH. Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds. Environmental and Molecular Mutagenesis. 50: 213-21. PMID 19197985 DOI: 10.1002/Em.20454 |
0.705 |
|
| 2009 |
Castro DJ, Löhr CV, Fischer KA, Waters KM, Webb-Robertson BJ, Dashwood RH, Bailey GS, Williams DE. Identifying efficacious approaches to chemoprevention with chlorophyllin, purified chlorophylls and freeze-dried spinach in a mouse model of transplacental carcinogenesis. Carcinogenesis. 30: 315-20. PMID 19073876 DOI: 10.1093/Carcin/Bgn280 |
0.318 |
|
| 2009 |
Ashktorab H, Belgrave K, Hosseinkhah F, Brim H, Nouraie M, Takkikto M, Hewitt S, Lee EL, Dashwood RH, Smoot D. Global histone H4 acetylation and HDAC2 expression in colon adenoma and carcinoma. Digestive Diseases and Sciences. 54: 2109-17. PMID 19057998 DOI: 10.1007/S10620-008-0601-7 |
0.442 |
|
| 2008 |
Dashwood RH, Ho E. Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates. Nutrition Reviews. 66: S36-8. PMID 18673487 DOI: 10.1111/J.1753-4887.2008.00065.X |
0.547 |
|
| 2008 |
Castro DJ, Yu Z, Löhr CV, Pereira CB, Giovanini JN, Fischer KA, Orner GA, Dashwood RH, Williams DE. Chemoprevention of dibenzo[a,l]pyrene transplacental carcinogenesis in mice born to mothers administered green tea: primary role of caffeine. Carcinogenesis. 29: 1581-6. PMID 18635525 DOI: 10.1093/Carcin/Bgm237 |
0.31 |
|
| 2008 |
Nian H, Delage B, Pinto JT, Dashwood RH. Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter. Carcinogenesis. 29: 1816-24. PMID 18628250 DOI: 10.1093/Carcin/Bgn165 |
0.665 |
|
| 2008 |
Wang R, Dashwood WM, Löhr CV, Fischer KA, Nakagama H, Williams DE, Dashwood RH. beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet. Cancer Science. 99: 1754-9. PMID 18616682 DOI: 10.1111/J.1349-7006.2008.00887.X |
0.346 |
|
| 2008 |
Delage B, Dashwood RH. Dietary manipulation of histone structure and function. Annual Review of Nutrition. 28: 347-66. PMID 18598138 DOI: 10.1146/Annurev.Nutr.28.061807.155354 |
0.39 |
|
| 2008 |
Clarke JD, Dashwood RH, Ho E. Multi-targeted prevention of cancer by sulforaphane. Cancer Letters. 269: 291-304. PMID 18504070 DOI: 10.1016/J.Canlet.2008.04.018 |
0.488 |
|
| 2008 |
Wang R, Dashwood WM, Löhr CV, Fischer KA, Pereira CB, Louderback M, Nakagama H, Bailey GS, Williams DE, Dashwood RH. Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat. Carcinogenesis. 29: 834-9. PMID 18283038 DOI: 10.1093/Carcin/Bgn051 |
0.357 |
|
| 2008 |
Simonich MT, McQuistan T, Jubert C, Pereira C, Hendricks JD, Schimerlik M, Zhu B, Dashwood RH, Williams DE, Bailey GS. Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 46: 1014-24. PMID 18069110 DOI: 10.1016/J.Fct.2007.10.034 |
0.322 |
|
| 2008 |
Wang R, Dashwood W, Nian H, Tsuchiya N, Nakagama H, Dashwood R. Abstract B84: NADPH oxidase 1 (NOX1) and related NOX isoforms as key mediators of NFκB signaling in colon cancer Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-B84 |
0.623 |
|
| 2007 |
Dashwood RH, Ho E. Dietary histone deacetylase inhibitors: from cells to mice to man. Seminars in Cancer Biology. 17: 363-9. PMID 17555985 DOI: 10.1016/J.Semcancer.2007.04.001 |
0.561 |
|
| 2007 |
Li Q, Dashwood WM, Zhong X, Nakagama H, Dashwood RH. Bcl-2 overexpression in PhIP-induced colon tumors: Cloning of the rat Bcl-2 promoter and characterization of a pathway involving β-catenin, c-Myc and E2F1 Oncogene. 26: 6194-6202. PMID 17404573 DOI: 10.1038/Sj.Onc.1210438 |
0.348 |
|
| 2007 |
Higdon JV, Delage B, Williams DE, Dashwood RH. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 55: 224-36. PMID 17317210 DOI: 10.1016/J.Phrs.2007.01.009 |
0.395 |
|
| 2007 |
Myzak MC, Tong P, Dashwood WM, Dashwood RH, Ho E. Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects. Experimental Biology and Medicine (Maywood, N.J.). 232: 227-34. PMID 17259330 DOI: 10.3181/00379727-207-2320227 |
0.815 |
|
| 2007 |
Dashwood RH. Frontiers in polyphenols and cancer prevention. The Journal of Nutrition. 137: 267S-269S. PMID 17182838 DOI: 10.1093/Jn/137.1.267S |
0.395 |
|
| 2006 |
Kwon D, Yoon S, Carter O, Bailey GS, Dashwood RH. Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. Biofactors (Oxford, England). 26: 231-44. PMID 17119270 DOI: 10.1002/Biof.5520260402 |
0.362 |
|
| 2006 |
Dashwood RH. Xenobiotic metabolism relevance to cancer. The Journal of Nutrition. 136: 2681S-2S. PMID 16988148 DOI: 10.1093/Jn/136.10.2681S |
0.406 |
|
| 2006 |
Wang R, Dashwood WM, Bailey GS, Williams DE, Dashwood RH. Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status. Mutation Research. 601: 11-8. PMID 16860348 DOI: 10.1016/J.Mrfmmm.2006.05.026 |
0.302 |
|
| 2006 |
Myzak MC, Ho E, Dashwood RH. Dietary agents as histone deacetylase inhibitors. Molecular Carcinogenesis. 45: 443-6. PMID 16652377 DOI: 10.1002/Mc.20224 |
0.821 |
|
| 2006 |
Myzak MC, Dashwood RH. Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane. Current Drug Targets. 7: 443-52. PMID 16611031 DOI: 10.2174/138945006776359467 |
0.817 |
|
| 2006 |
Myzak MC, Dashwood RH. Chemoprotection by sulforaphane: keep one eye beyond Keap1. Cancer Letters. 233: 208-18. PMID 16520150 DOI: 10.1016/J.Canlet.2005.02.033 |
0.804 |
|
| 2006 |
Myzak MC, Dashwood WM, Orner GA, Ho E, Dashwood RH. Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 506-8. PMID 16407454 DOI: 10.1096/Fj.05-4785Fje |
0.813 |
|
| 2006 |
Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E. Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells. Carcinogenesis. 27: 811-9. PMID 16280330 DOI: 10.1093/Carcin/Bgi265 |
0.802 |
|
| 2006 |
Dashwood RH, Myzak MC, Ho E. Dietary HDAC inhibitors: time to rethink weak ligands in cancer chemoprevention? Carcinogenesis. 27: 344-9. PMID 16267097 DOI: 10.1093/Carcin/Bgi253 |
0.821 |
|
| 2005 |
Dashwood WM, Carter O, Al-Fageeh M, Li Q, Dashwood RH. Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate. Mutation Research. 591: 161-72. PMID 16054165 DOI: 10.1016/J.Mrfmmm.2005.03.029 |
0.335 |
|
| 2004 |
Carter O, Bailey GS, Dashwood RH. The dietary phytochemical chlorophyllin alters E-cadherin and beta-catenin expression in human colon cancer cells. The Journal of Nutrition. 134: 3441S-3444S. PMID 15570051 DOI: 10.1093/Jn/134.12.3441S |
0.398 |
|
| 2004 |
Yu TW, Xu M, Dashwood RH. Antimutagenic activity of spearmint. Environmental and Molecular Mutagenesis. 44: 387-93. PMID 15529323 DOI: 10.1002/Em.20063 |
0.335 |
|
| 2004 |
Li Q, Dashwood RH. Activator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cells. The Journal of Biological Chemistry. 279: 45669-75. PMID 15331612 DOI: 10.1074/Jbc.M405025200 |
0.332 |
|
| 2004 |
Myzak MC, Karplus PA, Chung FL, Dashwood RH. A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. Cancer Research. 64: 5767-74. PMID 15313918 DOI: 10.1158/0008-5472.Can-04-1326 |
0.824 |
|
| 2004 |
Al-Fageeh M, Li Q, Dashwood WM, Myzak MC, Dashwood RH. Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32. Oncogene. 23: 4839-46. PMID 15064718 DOI: 10.1038/Sj.Onc.1207634 |
0.748 |
|
| 2004 |
Li Q, Dashwood WM, Zhong X, Al-Fageeh M, Dashwood RH. Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters. Genomics. 83: 231-42. PMID 14706452 DOI: 10.1016/J.Ygeno.2003.08.004 |
0.352 |
|
| 2003 |
Blum CA, Tanaka T, Zhong X, Li Q, Dashwood WM, Pereira C, Xu M, Dashwood RH. Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun. Molecular Carcinogenesis. 36: 195-203. PMID 12669311 DOI: 10.1002/Mc.10112 |
0.328 |
|
| 2003 |
Blum CA, Xu M, Orner GA, Darío Díaz G, Li Q, Dashwood WM, Bailey GS, Dashwood RH. Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling. Mutation Research. 523: 217-23. PMID 12628520 DOI: 10.1016/S0027-5107(02)00338-X |
0.386 |
|
| 2003 |
Orner GA, Dashwood WM, Blum CA, Díaz GD, Li Q, Dashwood RH. Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac. Carcinogenesis. 24: 263-7. PMID 12584176 DOI: 10.1093/Carcin/24.2.263 |
0.338 |
|
| 2003 |
Dashwood RH. Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis. Journal of Biochemistry and Molecular Biology. 36: 35-42. PMID 12542973 DOI: 10.5483/Bmbrep.2003.36.1.035 |
0.329 |
|
| 2002 |
Orner GA, Dashwood WM, Blum CA, Díaz GD, Li Q, Al-Fageeh M, Tebbutt N, Heath JK, Ernst M, Dashwood RH. Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Mutation Research. 506: 121-7. PMID 12351151 DOI: 10.1016/S0027-5107(02)00158-6 |
0.363 |
|
| 2002 |
Dashwood WM, Orner GA, Dashwood RH. Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations. Biochemical and Biophysical Research Communications. 296: 584-8. PMID 12176021 DOI: 10.1016/S0006-291X(02)00914-2 |
0.363 |
|
| 2002 |
Franke AA, Custer LJ, Cooney RV, Tanaka Y, Xu M, Dashwood RH. Inhibition of colonic aberrant crypt formation by the dietary flavonoids (+)-catechin and hesperidin. Advances in Experimental Medicine and Biology. 505: 123-33. PMID 12083456 DOI: 10.1007/978-1-4757-5235-9_11 |
0.325 |
|
| 2002 |
Dashwood RH. Modulation of heterocyclic amine-induced mutagenicity and carcinogenicity: an 'A-to-Z' guide to chemopreventive agents, promoters, and transgenic models. Mutation Research. 511: 89-112. PMID 12052429 DOI: 10.1016/S1383-5742(02)00005-4 |
0.39 |
|
| 2002 |
Amantana A, Santana-Rios G, Butler JA, Xu M, Whanger PD, Dashwood RH. Antimutagenic activity of selenium-enriched green tea toward the heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline. Biological Trace Element Research. 86: 177-91. PMID 12008980 DOI: 10.1385/Bter:86:2:177 |
0.358 |
|
| 2002 |
Li Q, Dixon BM, Al-Fageeh M, Blum CA, Dashwood RH. Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline. Gene. 283: 255-62. PMID 11867232 DOI: 10.1016/S0378-1119(01)00839-3 |
0.331 |
|
| 2001 |
Santana-Rios G, Orner GA, Xu M, Izquierdo-Pulido M, Dashwood RH. Inhibition by white tea of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced colonic aberrant crypts in the F344 rat Nutrition and Cancer. 41: 98-103. PMID 12094635 DOI: 10.1080/01635581.2001.9680618 |
0.332 |
|
| 2001 |
Santana-Rios G, Orner GA, Amantana A, Provost C, Wu SY, Dashwood RH. Potent antimutagenic activity of white tea in comparison with green tea in the Salmonella assay Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 495: 61-74. PMID 11448643 DOI: 10.1016/S1383-5718(01)00200-5 |
0.338 |
|
| 2001 |
Yu Z, Xu M, Santana-Rios G, Shen R, Izquierdo-Pulido M, Williams DE, Dashwood RH. A comparison of whole wheat, refined wheat and wheat bran as inhibitors of heterocyclic amines in the Salmonella mutagenicity assay and in the rat colonic aberrant crypt focus assay Food and Chemical Toxicology. 39: 655-665. PMID 11397513 DOI: 10.1016/S0278-6915(01)00012-6 |
0.366 |
|
| 2001 |
Dashwood RH, Xu M, Orner GA, Horio DT. Colonic cell proliferation, apoptosis and aberrant crypt foci development in rats given 2-amino-3-methylimidazo[4,5-f]quinoline and treated postinitiation with chlorophyllin European Journal of Cancer Prevention. 10: 139-145. PMID 11330454 DOI: 10.1097/00008469-200104000-00004 |
0.362 |
|
| 2001 |
Blum CA, Xu M, Orner GA, Fong AT, Bailey GS, Stoner GD, Horio DT, Dashwood RH. β-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol Carcinogenesis. 22: 315-320. PMID 11181454 DOI: 10.1093/Carcin/22.2.315 |
0.317 |
|
| 2001 |
Xu M, Orner GA, Bailey GS, Stoner GD, Horio DT, Dashwood RH. Post-initiation effects of chlorophyllin and indole-3-carbinol in rats given 1,2-dimethylhydrazine or 2-amino-3-methyl-imidazo[4,5-f]quinoline Carcinogenesis. 22: 309-314. PMID 11181453 DOI: 10.1093/Carcin/22.2.309 |
0.342 |
|
| 1999 |
Xu M, Dashwood RH. Chemoprevention studies of heterocyclic amine-induced colon carcinogenesis Cancer Letters. 143: 179-183. PMID 10503900 DOI: 10.1016/S0304-3835(99)00121-4 |
0.409 |
|
| 1999 |
Suzui M, Ushijima T, Dashwood RH, Yoshimi N, Sugimura T, Mori H, Nagao M. Frequent mutations of the rat β-catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1-hydroxyanthraquinone Molecular Carcinogenesis. 24: 232-237. PMID 10204808 DOI: 10.1002/(Sici)1098-2744(199903)24:3<232::Aid-Mc10>3.0.Co;2-M |
0.322 |
|
| 1999 |
Dashwood RH, Xu M, Hernaez JF, Hasaniya N, Youn K, Razzuk A. Cancer chemopreventive mechanisms of tea against heterocyclic amine mutagens from cooked meat Proceedings of the Society For Experimental Biology and Medicine. 220: 239-243. PMID 10202396 DOI: 10.1046/J.1525-1373.1999.D01-41.X |
0.421 |
|
| 1999 |
Dashwood RH. Early detection and prevention of colorectal cancer (review) Oncology Reports. 6: 277-281. PMID 10022989 |
0.304 |
|
| 1998 |
Dashwood RH. The "Sufficiency Principle" from the perspective of cancer prevention Japanese Journal of Clinical Oncology. 28: 410-411. PMID 9730159 DOI: 10.1093/Jjco/28.6.410 |
0.382 |
|
| 1998 |
Dashwood RH. Cancer chemoprevention from the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine [1] Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 405: 109-110. PMID 9729314 DOI: 10.1016/S0027-5107(98)00119-5 |
0.336 |
|
| 1998 |
Hernaez JF, Xu M, Dashwood RH. Antimutagenic activity of tea towards 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline: Effect of tea concentration and brew time on electrophile scavenging Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 402: 299-306. PMID 9675318 DOI: 10.1016/S0027-5107(97)00309-6 |
0.323 |
|
| 1998 |
Dashwood R, Negishi T, Hayatsu H, Breinholt V, Hendricks J, Bailey G. Chemopreventive properties of chlorophylls towards aflatoxin B1: a review of the antimutagenicity and anticarcinogenicity data in rainbow trout. Mutation Research. 399: 245-53. PMID 9672663 DOI: 10.1016/S0027-5107(97)00259-5 |
0.351 |
|
| 1998 |
Dashwood RH. Indole-3-carbinol: Anticarcinogen or tumor promoter in brassica vegetables? Chemico-Biological Interactions. 110: 1-5. PMID 9566721 DOI: 10.1016/S0009-2797(97)00115-4 |
0.343 |
|
| 1998 |
Hernaez J, Xu M, Dashwood R. Effects of tea and chlorophyllin on the mutagenicity of N-hydroxy-IQ: studies of enzyme inhibition, molecular complex formation, and degradation/scavenging of the active metabolites. Environmental and Molecular Mutagenesis. 30: 468-74. PMID 9435888 DOI: 10.1002/(Sici)1098-2280(1997)30:4<468::Aid-Em12>3.0.Co;2-B |
0.354 |
|
| 1997 |
Hasaniya N, Youn K, Xu M, Hernaez J, Dashwood R. Inhibitory activity of green and black tea in a free radical-generating system using 2-amino-3-methylimidazo[4,5-f]quinoline as substrate. Japanese Journal of Cancer Research : Gann. 88: 553-8. PMID 9263532 DOI: 10.1111/J.1349-7006.1997.Tb00418.X |
0.32 |
|
| 1997 |
Dashwood RH. Chlorophylls as anticarcinogens International Journal of Oncology. 10: 721-727. |
0.321 |
|
| 1996 |
Xu M, Bailey AC, Hernaez JF, Taoka CR, Schut HA, Dashwood RH. Protection by green tea, black tea, and indole-3-carbinol against 2-amino-3-methylimidazo[4,5-f]quinoline-induced DNA adducts and colonic aberrant crypts in the F344 rat. Carcinogenesis. 17: 1429-34. PMID 8706244 DOI: 10.1093/Carcin/17.7.1429 |
0.334 |
|
| 1995 |
Liew C, Schut HAJ, Chin SF, Pariza MW, Dashwood RH. Protection of conjugated linoleic acids against 2-amino-3-methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the f344 rat: A study of inhibitory mechanisms Carcinogenesis. 16: 3037-3043. PMID 8603482 DOI: 10.1093/Carcin/16.12.3037 |
0.34 |
|
| 1995 |
Guo D, Schut HAJ, Davis CD, Snyderwine EG, Bailey GS, Dashwood RH. Protection by chlorophyllin and indole-3-carbinol against 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced DNA adducts and colonic aberrant crypts in the f344 rat Carcinogenesis. 16: 2931-2937. PMID 8603466 DOI: 10.1093/Carcin/16.12.2931 |
0.346 |
|
| 1994 |
Guo D, Dashwood R. Inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA binding in rats given chlorophyllin: dose-response and time-course studies in the liver and colon. Carcinogenesis. 15: 763-6. PMID 8149493 DOI: 10.1093/Carcin/15.4.763 |
0.331 |
|
| 1993 |
Fong AT, Dashwood RH, Cheng R, Mathews C, Ford B, Hendricks JD, Bailey GS. Carcinogenicity, metabolism and Ki-ras proto-oncogene activation by 7,12-dimethylbenz[a]anthracene in rainbow trout embryos. Carcinogenesis. 14: 629-35. PMID 8472326 DOI: 10.1093/Carcin/14.4.629 |
0.301 |
|
| 1993 |
Dashwood R, Guo D. Antimutagenic potency of chlorophyllin in the Salmonella assay and its correlation with binding constants of mutagen-inhibitor complexes. Environmental and Molecular Mutagenesis. 22: 164-71. PMID 8404876 DOI: 10.1002/Em.2850220309 |
0.341 |
|
| 1992 |
Dashwood RH. Protection by chlorophyllin against the covalent binding of 2-amino-3-methylimidazo[4,5-f]qiiinoline (IQ) to rat liver DNA Carcinogenesis. 13: 113-118. PMID 1733563 DOI: 10.1093/Carcin/13.1.113 |
0.302 |
|
| 1992 |
Dashwood R, Guo D. Inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA binding by chlorophyllin: studies of enzyme inhibition and molecular complex formation. Carcinogenesis. 13: 1121-6. PMID 1638677 DOI: 10.1093/Carcin/13.7.1121 |
0.302 |
|
| 1992 |
Dashwood R, Liew C. Chlorophyllin-enhanced excretion of urinary and fecal mutagens in rats given 2-amino-3-methylimidazo[4,5-f]quinoline. Environmental and Molecular Mutagenesis. 20: 199-205. PMID 1396610 DOI: 10.1002/Em.2850200308 |
0.313 |
|
| 1990 |
Dashwood RH, Fong AT, Hendricks JD, Bailey GS. Tumor dose-response studies with aflatoxin B1 and the ambivalent modulator indole-3-carbinol: inhibitory versus promotional potency. Basic Life Sciences. 52: 361-5. PMID 2109597 DOI: 10.1007/978-1-4615-9561-8_33 |
0.31 |
|
| 1990 |
Fong AT, Swanson HI, Dashwood RH, Williams DE, Hendricks JD, Bailey GS. Mechanisms of anti-carcinogenesis by indole-3-carbinol. Studies of enzyme induction, electrophile-scavenging, and inhibition of aflatoxin B1 activation. Biochemical Pharmacology. 39: 19-26. PMID 2105094 DOI: 10.1016/0006-2952(90)90643-Y |
0.338 |
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