Roberta Pelanda - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Immunology, Molecular Biology, Biochemistry

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mathew D, Kremer KN, Strauch P, Tigyi G, Pelanda R, Torres RM. LPA Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling. Frontiers in Immunology. 10: 1159. PMID 31231367 DOI: 10.3389/fimmu.2019.01159  0.44
2019 Greaves SA, Peterson JN, Strauch P, Torres RM, Pelanda R. Active PI3K abrogates central tolerance in high-avidity autoreactive B cells. The Journal of Experimental Medicine. PMID 30948496 DOI: 10.1084/jem.20181652  0.44
2018 Greaves SA, Peterson JN, Torres RM, Pelanda R. Corrigendum: Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance. Frontiers in Immunology. 9: 2218. PMID 30323810 DOI: 10.3389/fimmu.2018.02218  0.44
2018 Sang A, Danhorn T, Peterson JN, Rankin AL, O'Connor BP, Leach SM, Torres RM, Pelanda R. Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus. Nature Communications. 9: 3973. PMID 30266981 DOI: 10.1038/s41467-018-06293-z  0.44
2018 Agazio AE, Pelanda R, Torres RM. Silencing of TLM B cells by chronic HIV infection. Nature Immunology. 19: 902-903. PMID 30104630 DOI: 10.1038/s41590-018-0191-2  0.44
2018 Greaves SA, Peterson JN, Torres RM, Pelanda R. Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance. Frontiers in Immunology. 9: 707. PMID 29686680 DOI: 10.3389/fimmu.2018.00707  0.44
2017 Lang J, Zhang B, Kelly M, Peterson JN, Barbee J, Freed BM, Di Santo JP, Matsuda JL, Torres RM, Pelanda R. Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice. Blood Advances. 1: 2729-2741. PMID 29296925 DOI: 10.1182/bloodadvances.2017010090  0.44
2017 Schroeder KMS, Agazio A, Strauch PJ, Jones ST, Thompson SB, Harper MS, Pelanda R, Santiago ML, Torres RM. Breaching peripheral tolerance promotes the production of HIV-1-neutralizing antibodies. The Journal of Experimental Medicine. PMID 28698284 DOI: 10.1084/jem.20161190  0.44
2015 Lang J, Ota T, Kelly M, Strauch P, Freed BM, Torres RM, Nemazee D, Pelanda R. Receptor editing and genetic variability in human autoreactive B cells. The Journal of Experimental Medicine. PMID 26694971 DOI: 10.1084/jem.20151039  0.44
2015 Hobeika E, Levit-Zerdoun E, Anastasopoulou V, Pohlmeyer R, Altmeier S, Alsadeq A, Dobenecker MW, Pelanda R, Reth M. CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk. The Embo Journal. 34: 925-39. PMID 25630702 DOI: 10.15252/embj.201489732  0.44
2014 Teodorovic LS, Babolin C, Rowland SL, Greaves SA, Baldwin DP, Torres RM, Pelanda R. Activation of Ras overcomes B-cell tolerance to promote differentiation of autoreactive B cells and production of autoantibodies Proceedings of the National Academy of Sciences of the United States of America. 111: E2797-E2806. PMID 24958853 DOI: 10.1073/pnas.1402159111  0.44
2014 Hu J, Oda SK, Shotts K, Donovan EE, Strauch P, Pujanauski LM, Victorino F, Al-Shami A, Fujiwara Y, Tigyi G, Oravecz T, Pelanda R, Torres RM. Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response. Journal of Immunology (Baltimore, Md. : 1950). 193: 85-95. PMID 24890721 DOI: 10.4049/jimmunol.1300429  0.44
2014 Pelanda R. Dual immunoglobulin light chain B cells: Trojan horses of autoimmunity? Current Opinion in Immunology. 27: 53-9. PMID 24549093 DOI: 10.1016/j.coi.2014.01.012  0.44
2013 Oda SK, Strauch P, Fujiwara Y, Al-Shami A, Oravecz T, Tigyi G, Pelanda R, Torres RM. Lysophosphatidic acid inhibits CD8 T cell activation and control of tumor progression. Cancer Immunology Research. 1: 245-55. PMID 24455753 DOI: 10.1158/2326-6066.CIR-13-0043-T  0.44
2013 Feldman AG, Tucker RM, Fenner EK, Pelanda R, Mack CL. B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia. Plos One. 8: e73644. PMID 23991203 DOI: 10.1371/journal.pone.0073644  0.44
2013 Fuquay R, Renner B, Kulik L, McCullough JW, Amura C, Strassheim D, Pelanda R, Torres R, Thurman JM. Renal ischemia-reperfusion injury amplifies the humoral immune response. Journal of the American Society of Nephrology : Jasn. 24: 1063-72. PMID 23641055 DOI: 10.1681/ASN.2012060560  0.44
2013 Lang J, Kelly M, Freed BM, McCarter MD, Kedl RM, Torres RM, Pelanda R. Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 190: 2090-101. PMID 23335750 DOI: 10.4049/jimmunol.1202810  0.44
2013 Pujanauski LM, Janoff EN, McCarter MD, Pelanda R, Torres RM. Mouse marginal zone B cells harbor specificities similar to human broadly neutralizing HIV antibodies. Proceedings of the National Academy of Sciences of the United States of America. 110: 1422-7. PMID 23288906 DOI: 10.1073/pnas.1213713110  0.44
2013 Swanson CL, Pelanda R, Torres RM. Division of labor during primary humoral immunity. Immunologic Research. 55: 277-86. PMID 22945808 DOI: 10.1007/s12026-012-8372-9  0.44
2013 Rowland SL, Tuttle K, Torres RM, Pelanda R. Antigen and cytokine receptor signals guide the development of the naïve mature B cell repertoire Immunologic Research. 55: 231-240. PMID 22941591 DOI: 10.1007/s12026-012-8366-7  0.44
2012 Hartney JM, Chu H, Pelanda R, Torres RM. Sub-chronic exposure to second hand smoke induces airspace leukocyte infiltration and decreased lung elastance. Frontiers in Physiology. 3: 300. PMID 22934051 DOI: 10.3389/fphys.2012.00300  0.44
2012 Fournier EM, Velez MG, Leahy K, Swanson CL, Rubtsov AV, Torres RM, Pelanda R. Dual-reactive B cells are autoreactive and highly enriched in the plasmablast and memory B cell subsets of autoimmune mice. The Journal of Experimental Medicine. 209: 1797-812. PMID 22927551 DOI: 10.1084/jem.20120332  0.44
2012 Larson JD, Thurman JM, Rubtsov AV, Claypool D, Marrack P, van Dyk LF, Torres RM, Pelanda R. Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 109: E1092-100. PMID 22474381 DOI: 10.1073/pnas.1203019109  0.44
2012 Pelanda R, Torres RM. Central B-cell tolerance: where selection begins. Cold Spring Harbor Perspectives in Biology. 4: a007146. PMID 22378602 DOI: 10.1101/cshperspect.a007146  0.44
2012 Teodorovic LS, Riccardi C, Torres RM, Pelanda R. Murine B cell development and antibody responses to model antigens are not impaired in the absence of the TNF receptor GITR. Plos One. 7: e31632. PMID 22328941 DOI: 10.1371/journal.pone.0031632  0.44
2011 Hartney JM, Gustafson CE, Bowler RP, Pelanda R, Torres RM. Thromboxane receptor signaling is required for fibronectin-induced matrix metalloproteinase 9 production by human and murine macrophages and is attenuated by the Arhgef1 molecule. The Journal of Biological Chemistry. 286: 44521-31. PMID 22086927 DOI: 10.1074/jbc.M111.282772  0.44
2011 Eschbach C, Bach MP, Fidler I, Pelanda R, Köhler F, Rajewsky K, Jumaa H. Efficient generation of B lymphocytes by recognition of self-antigens. European Journal of Immunology. 41: 2397-403. PMID 21604259 DOI: 10.1002/eji.201041344  0.44
2011 Lang J, Weiss N, Freed BM, Torres RM, Pelanda R. Generation of hematopoietic humanized mice in the newborn BALB/c-Rag2null Il2rγnull mouse model: a multivariable optimization approach. Clinical Immunology (Orlando, Fla.). 140: 102-16. PMID 21536497 DOI: 10.1016/j.clim.2011.04.002  0.44
2011 Santiago ML, Smith DS, Barrett BS, Montano M, Benitez RL, Pelanda R, Hasenkrug KJ, Greene WC. Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor. Journal of Virology. 85: 189-99. PMID 20980520 DOI: 10.1128/JVI.01838-10  0.44
2010 Rowland SL, Leahy KF, Halverson R, Torres RM, Pelanda R. BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling Journal of Immunology. 185: 4570-4581. PMID 20861359 DOI: 10.4049/jimmunol.1001708  0.44
2010 Swanson CL, Wilson TJ, Strauch P, Colonna M, Pelanda R, Torres RM. Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response. The Journal of Experimental Medicine. 207: 1485-500. PMID 20566717 DOI: 10.1084/jem.20092695  0.44
2010 Rowland SL, DePersis CL, Torres RM, Pelanda R. Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation Journal of Experimental Medicine. 207: 607-621. PMID 20176802 DOI: 10.1084/jem.20091673  0.44
2010 Hartney JM, Brown J, Chu HW, Chang LY, Pelanda R, Torres RM. Arhgef1 regulates alpha5beta1 integrin-mediated matrix metalloproteinase expression and is required for homeostatic lung immunity. The American Journal of Pathology. 176: 1157-68. PMID 20093499 DOI: 10.2353/ajpath.2010.090200  0.44
2010 Donovan EE, Pelanda R, Torres RM. S1P3 confers differential S1P-induced migration by autoreactive and non-autoreactive immature B cells and is required for normal B-cell development. European Journal of Immunology. 40: 688-98. PMID 20039302 DOI: 10.1002/eji.200939858  0.44
2008 Pelanda R, Piccirillo CA. Tolerance, immune regulation, and autoimmunity: cells and cytokines that make a difference. Current Opinion in Immunology. 20: 629-31. PMID 18977298 DOI: 10.1016/j.coi.2008.10.005  0.44
2008 Rubtsov AV, Swanson CL, Troy S, Strauch P, Pelanda R, Torres RM. TLR agonists promote marginal zone B cell activation and facilitate T-dependent IgM responses. Journal of Immunology (Baltimore, Md. : 1950). 180: 3882-8. PMID 18322196  0.44
2008 Hu J, Strauch P, Rubtsov A, Donovan EE, Pelanda R, Torres RM. Lsc activity is controlled by oligomerization and regulates integrin adhesion. Molecular Immunology. 45: 1825-36. PMID 18157933 DOI: 10.1016/j.molimm.2007.11.002  0.44
2007 Velez MG, Kane M, Liu S, Gauld SB, Cambier JC, Torres RM, Pelanda R. Ig allotypic inclusion does not prevent B cell development or response. Journal of Immunology (Baltimore, Md. : 1950). 179: 1049-57. PMID 17617597  0.44
2007 Fraenkel S, Mostoslavsky R, Novobrantseva TI, Pelanda R, Chaudhuri J, Esposito G, Jung S, Alt FW, Rajewsky K, Cedar H, Bergman Y. Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus. Nature Immunology. 8: 715-22. PMID 17546032 DOI: 10.1038/ni1476  0.44
2007 Liu H, Schmidt-Supprian M, Shi Y, Hobeika E, Barteneva N, Jumaa H, Pelanda R, Reth M, Skok J, Rajewsky K. Yin Yang 1 is a critical regulator of B-cell development Genes and Development. 21: 1179-1189. PMID 17504937 DOI: 10.1101/gad.1529307  0.44
2007 Brown JP, Taube C, Miyahara N, Koya T, Pelanda R, Gelfand EW, Torres RM. Arhgef1 is required by T cells for the development of airway hyperreactivity and inflammation. American Journal of Respiratory and Critical Care Medicine. 176: 10-9. PMID 17463415 DOI: 10.1164/rccm.200702-270OC  0.44
2006 Hobeika E, Thiemann S, Storch B, Jumaa H, Nielsen PJ, Pelanda R, Reth M. Testing gene function early in the B cell lineage in mb1-cre mice Proceedings of the National Academy of Sciences of the United States of America. 103: 13789-13794. PMID 16940357 DOI: 10.1073/pnas.0605944103  0.44
2006 Sasaki Y, Derudder E, Hobeika E, Pelanda R, Reth M, Rajewsky K, Schmidt-Supprian M. Canonical NF-κB Activity, Dispensable for B Cell Development, Replaces BAFF-Receptor Signals and Promotes B Cell Proliferation upon Activation Immunity. 24: 729-739. PMID 16782029 DOI: 10.1016/j.immuni.2006.04.005  0.44
2006 Pelanda R, Torres RM. Receptor editing for better or for worse. Current Opinion in Immunology. 18: 184-90. PMID 16460922 DOI: 10.1016/j.coi.2006.01.005  0.44
2005 Rubtsov A, Strauch P, Digiacomo A, Hu J, Pelanda R, Torres RM. Lsc regulates marginal-zone B cell migration and adhesion and is required for the IgM T-dependent antibody response. Immunity. 23: 527-38. PMID 16286020 DOI: 10.1016/j.immuni.2005.09.018  0.44
2005 Liu S, Velez MG, Humann J, Rowland S, Conrad FJ, Halverson R, Torres RM, Pelanda R. Receptor editing can lead to allelic inclusion and development of B cells that retain antibodies reacting with high avidity autoantigens. Journal of Immunology (Baltimore, Md. : 1950). 175: 5067-76. PMID 16210610  0.44
2005 Novobrantseva T, Xu S, Tan JE, Maruyama M, Schwers S, Pelanda R, Lam KP. Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo. International Immunology. 17: 343-50. PMID 15710909 DOI: 10.1093/intimm/dxh214  0.44
2004 Galler GR, Mundt C, Parker M, Pelanda R, Mårtensson IL, Winkler TH. Surface mu heavy chain signals down-regulation of the V(D)J-recombinase machinery in the absence of surrogate light chain components. The Journal of Experimental Medicine. 199: 1523-32. PMID 15173209 DOI: 10.1084/jem.20031523  0.44
2004 Halverson R, Torres RM, Pelanda R. Receptor editing is the main mechanism of B cell tolerance toward membrane antigens. Nature Immunology. 5: 645-50. PMID 15156139 DOI: 10.1038/ni1076  0.44
2004 Heinrich AC, Pelanda R, Klingmüller U. A mouse model for visualization and conditional mutations in the erythroid lineage. Blood. 104: 659-66. PMID 15090451 DOI: 10.1182/blood-2003-05-1442  0.44
2002 Pelanda R, Braun U, Hobeika E, Nussenzweig MC, Reth M. B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta. Journal of Immunology (Baltimore, Md. : 1950). 169: 865-72. PMID 12097390  0.44
2002 Pelanda R, Hobeika E, Kurokawa T, Zhang Y, Kuppig S, Reth M. Cre recombinase-controlled expression of the mb-1 allele. Genesis (New York, N.Y. : 2000). 32: 154-7. PMID 11857807 DOI: 10.1002/gene.10070  0.44
2000 Braun U, Rajewsky K, Pelanda R. Different sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenes Proceedings of the National Academy of Sciences of the United States of America. 97: 7429-7434. PMID 10829061 DOI: 10.1073/pnas.050578497  0.44
1999 Korganow AS, Ji H, Mangialaio S, Duchatelle V, Pelanda R, Martin T, Degott C, Kikutani H, Rajewsky K, Pasquali JL, Benoist C, Mathis D. From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity. 10: 451-61. PMID 10229188 DOI: 10.1016/S1074-7613(00)80045-X  0.44
1999 Novobrantseva TI, Martin VM, Pelanda R, Müller W, Rajewsky K, Ehlich A. Rearrangement and expression of immunoglobulin light chain genes can precede heavy chain expression during normal B cell development in mice Journal of Experimental Medicine. 189: 75-87. PMID 9874565 DOI: 10.1084/jem.189.1.75  0.44
1998 Mostoslavsky R, Singh N, Kirillov A, Pelanda R, Cedar H, Chess A, Bergman Y. Kappa chain monoallelic demethylation and the establishment of allelic exclusion. Genes & Development. 12: 1801-11. PMID 9637682  0.44
1998 Casellas R, Nussenzweig A, Wuerffel R, Pelanda R, Reichlin A, Suh H, Qin XF, Besmer E, Kenter A, Rajewsky K, Nussenzweig MC. Ku80 is required for immunoglobulin isotype switching Embo Journal. 17: 2404-2411. PMID 9545251 DOI: 10.1093/emboj/17.8.2404  0.44
1997 Pelanda R, Schwers S, Sonoda E, Torres RM, Nemazee D, Rajewsky K. Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity. 7: 765-75. PMID 9430222 DOI: 10.1016/S1074-7613(00)80395-7  0.44
1997 Papavasiliou F, Casellas R, Suh H, Qin XF, Besmer E, Pelanda R, Nemazee D, Rajewsky K, Nussenzweig MC. V(D)J recombination in mature B cells: a mechanism for altering antibody responses. Science (New York, N.Y.). 278: 298-301. PMID 9323210 DOI: 10.1126/science.278.5336.298  0.44
1996 Pelanda R, Schaal S, Torres RM, Rajewsky K. A prematurely expressed Igκ transgene, but not a VκJκ gene segment targeted into the Igκ locus, can rescue B cell development in λ5-deficient mice Immunity. 5: 229-239. PMID 8808678 DOI: 10.1016/S1074-7613(00)80318-0  0.44
1993 Pelanda R, Vanoni MA, Perego M, Piubelli L, Galizzi A, Curti B, Zanetti G. Glutamate synthase genes of the diazotroph Azospirillum brasilense: Cloning, sequencing, and analysis of functional domains Journal of Biological Chemistry. 268: 3099-3106. PMID 8428988  0.44
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