Richard B. Van Breemen - Publications

Affiliations: 
University of Illinois at Chicago, Health Sciences Center 
Area:
Pharmaceutical Chemistry, Analytical Chemistry, Biochemistry

315 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 van Breemen RB, Chen L, Tonsing-Carter A, Banuvar S, Barengolts E, Viana M, Chen SN, Pauli GF, Bolton JB. Pharmacokinetic interactions of a hop dietary supplement with drug metabolism in peri-menopausal and post-menopausal women. Journal of Agricultural and Food Chemistry. PMID 32285669 DOI: 10.1021/acs.jafc.0c01077  0.88
2020 Yu Y, Pauli GF, Huang L, Gan LS, van Breemen RB, Li D, McAlpine JB, Lankin DC, Chen SN. Classification of Flavonoid Metabolomes via Data Mining and Quantification of Hydroxyl NMR Signals. Analytical Chemistry. PMID 32108467 DOI: 10.1021/acs.analchem.9b05084  0.88
2020 van Breemen RB, Hathout Y, Fabris D. Catherine Fenselau: A distinguished career dedicated to biomedical mass spectrometry. Journal of Mass Spectrometry : Jms. 55: e4500. PMID 32073193 DOI: 10.1002/jms.4500  0.56
2019 Feinstein DL, Nosal DG, Ramanathan S, Zhou J, Chen L, Hershow RC, van Breemen RB, Wright E, Hafner JW, Rubinstein I. Effects of vitamin K1 treatment on plasma concentrations of long-acting anticoagulant rodenticide enantiomers following inhalation of contaminated synthetic cannabinoids. Clinical Toxicology (Philadelphia, Pa.). 1-9. PMID 31736367 DOI: 10.1080/15563650.2019.1687903  0.64
2019 Fang J, Nikolic D, Lankin DC, Simmler C, Chen SN, Ramos Alvarenga RF, Liu Y, Pauli GF, van Breemen RB. Formation of (2R)- and (2S)-8-Prenylnaringenin Glucuronides by Human UDP-Glucuronosyltransferases. Journal of Agricultural and Food Chemistry. PMID 31554401 DOI: 10.1021/acs.jafc.9b04657  0.88
2019 Bolton JL, Dunlap TL, Hajirahimkhan A, Mbachu O, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM. Correction to The Multiple Biological Targets of Hops and Bioactive Compounds. Chemical Research in Toxicology. PMID 31392882 DOI: 10.1021/acs.chemrestox.9b00300  0.92
2019 Bolton JL, Dunlap TL, Hajirahimkhan DA, Mbachu OC, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM. The Multiple Biological Targets of Hops and Bioactive Compounds. Chemical Research in Toxicology. PMID 30608650 DOI: 10.1021/acs.chemrestox.8b00345  0.92
2018 Wang S, Dunlap TL, Huang L, Liu Y, Simmler C, Lantvit DD, Crosby J, Howell CE, Dong H, Chen SN, Pauli GF, van Breemen RB, Dietz BM, Bolton JL. Evidence for Chemopreventive and resilience activity of licorice: Glycyrrhiza glabra and G. inflata extracts modulate estrogen metabolism in ACI rats. Cancer Prevention Research (Philadelphia, Pa.). PMID 30287522 DOI: 10.1158/1940-6207.CAPR-18-0178  0.92
2018 Abdelkarim H, Marshall MS, Scesa G, Smith RA, Rue E, Marshall J, Elackattu V, Stoskute M, Issa Y, Santos M, Nguyen D, Hauck Z, van Breemen R, Celej MS, Gaponenko V, et al. α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies. Scientific Reports. 8: 12462. PMID 30127535 DOI: 10.1038/s41598-018-30808-9  0.44
2018 Johnson HE, Amarillas C, Bzhelyansky A, Jennens M, Krepich S, Kuszak A, Monagas M, Parisi S, Reif K, Rimmer CA, Stewart J, Szpylka J, Tims MC, Van Breemen R, Zhao H. (SMPRs®) 2018.007: Identification of Skullcap in Raw Materials, Skullcap-Based Dietary Ingredients, and Dietary Supplements. Journal of Aoac International. 101: 1266-1267. PMID 29986803 DOI: 10.5740/jaoacint.SMPR2018.007  0.32
2018 Johnson HE, Amarillas C, Bzhelyansky A, Jennens M, Krepich S, Kuszak A, Monagas M, Parisi S, Reif K, Rimmer CA, Stewart J, Szpylka J, Tims MC, Van Breemen R, Zhao H, et al. (SMPRs®) 2018.006: Determination of Select Flavonoids from Skullcap. Journal of Aoac International. 101: 1261-1265. PMID 29986802 DOI: 10.5740/jaoacint.SMPR2018.006  0.32
2018 Dentali SJ, Amarillas C, Blythe T, Brown PN, Bzhelyansky A, Fields C, Johnson HE, Krepich S, Kuszak A, Metcalfe C, Monagas M, Mudge E, Parisi S, Reif K, Rimmer CA, ... ... Van Breemen R, et al. (SMPRs®) 2018.005: Determination of Kavalactones and/or Flavokavains from Kava (). Journal of Aoac International. 101: 1256-1260. PMID 29986801 DOI: 10.5740/jaoacint.SMPR2018.005  0.32
2018 Van Breemen R, Bzhelyansky A, Es-Safi NE, Jennens M, Johnson HE, Krepich S, Kuszak A, Monagas M, Reif K, Rimmer CA, Solyom AM, Stewart J, Szpylka J, You H, Young K, et al. (SMPRs®) 2018.004: Determination of Resveratrol in Dietary Supplements and Dietary Ingredients. Journal of Aoac International. 101: 1254-1255. PMID 29986800 DOI: 10.5740/jaoacint.SMPR2018.004  0.32
2018 Hajirahimkhan A, Mbachu O, Simmler C, Ellis SG, Dong H, Nikolic D, Lankin DC, van Breemen RB, Chen SN, Pauli GF, Dietz BM, Bolton JL. Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication. Journal of Natural Products. PMID 29641206 DOI: 10.1021/acs.jnatprod.7b01070  0.92
2018 Marshall MS, Jakubauskas B, Bogue W, Stoskute M, Hauck Z, Rue E, Nichols M, DiAntonio LL, van Breemen RB, Kordower JH, Saavedra-Matiz CA, Bongarzone ER. Analysis of age-related changes in psychosine metabolism in the human brain. Plos One. 13: e0193438. PMID 29481565 DOI: 10.1371/journal.pone.0193438  0.44
2017 Keiler AM, Helle J, Bader MI, Ehrhardt T, Nestler K, Kretzschmar G, Bernhardt R, Vollmer G, Nikolić D, Bolton JL, Pauli GF, Chen SN, Dietz BM, van Breemen RB, Zierau O. A standardized Humulus lupulus (L.) ethanol extract partially prevents ovariectomy-induced bone loss in the rat without induction of adverse effects in the uterus. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 34: 50-58. PMID 28899509 DOI: 10.1016/j.phymed.2017.08.001  0.92
2017 van Breemen R, Betz JM, Evans L, Hall A, Jennens M, Kreider R, Kuszak A, Mudge E, Patel P, Phillips MM, Rimmer CA, Schaneberg BT, Sheshadri A, Solyom AM, Sullivan DM, et al. AOAC SMPR 2016.017. Journal of Aoac International. 100: 294-296. PMID 28825562 DOI: 10.5740/jaoacint.SMPR2016.017  0.32
2017 Dietz BM, Chen SN, Alvarenga RFR, Dong H, Nikolić D, Biendl M, van Breemen RB, Bolton JL, Pauli GF. DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women's Health. Journal of Natural Products. PMID 28812892 DOI: 10.1021/acs.jnatprod.7b00284  0.92
2017 Li G, Simmler C, Chen L, Nikolic D, Chen SN, Pauli GF, van Breemen RB. Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28774812 DOI: 10.1016/j.ejps.2017.07.034  0.88
2017 Prins GS, Ye SH, Birch L, Zhang X, Cheong A, Lin H, Calderon-Gierszal E, Groen J, Hu WY, Ho SM, van Breemen RB. Prostate Cancer Risk and DNA Methylation Signatures in Aging Rats following Developmental BPA Exposure: A Dose-Response Analysis. Environmental Health Perspectives. 125: 077007. PMID 28728135 DOI: 10.1289/EHP1050  0.72
2017 Simmler C, Lankin DC, Nikolić D, van Breemen RB, Pauli GF. Isolation and structural characterization of dihydrobenzofuran congeners of licochalcone A. Fitoterapia. PMID 28647482 DOI: 10.1016/j.fitote.2017.06.017  0.88
2017 Nikolić D, Macias C, Lankin DC, van Breemen RB. Collision-induced dissociation of phenethylamides: role of ion-neutral complex. Rapid Communications in Mass Spectrometry : Rcm. PMID 28558170 DOI: 10.1002/rcm.7915  0.76
2017 D'Auria L, Reiter C, Ward E, Moyano AL, Marshall MS, Nguyen D, Scesa G, Hauck Z, van Breemen R, Givogri MI, Bongarzone ER. Psychosine enhances the shedding of membrane microvesicles: Implications in demyelination in Krabbe's disease. Plos One. 12: e0178103. PMID 28531236 DOI: 10.1371/journal.pone.0178103  0.44
2016 Li G, Nikolic D, van Breemen RB. Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS. Journal of Agricultural and Food Chemistry. PMID 27696846 DOI: 10.1021/acs.jafc.6b02954  0.88
2016 Moyano AL, Li G, Boullerne AI, Feinstein DL, Hartman E, Skias D, Balavanov R, van Breemen RB, Bongarzone ER, Månsson JE, Givogri MI. Sulfatides in extracellular vesicles isolated from plasma of multiple sclerosis patients. Journal of Neuroscience Research. PMID 27557608 DOI: 10.1002/jnr.23899  0.72
2016 Kondratyuk TP, Adrian JA, Wright B, Park EJ, van Breemen RB, Morris KR, Pezzuto JM. Evidence supporting the conceptual framework of cancer chemoprevention in canines. Scientific Reports. 6: 26500. PMID 27216246 DOI: 10.1038/srep26500  1
2016 Stahlhut RW, van Breemen RB, Gerona RR, Taylor JA, Welshons WV, Vom Saal FS. Comment on "Optimal Exposure Biomarkers for Nonpersistent Chemicals in Environmental Epidemiology". Environmental Health Perspectives. 124: A66. PMID 27035054 DOI: 10.1289/ehp.1511057  1
2016 Vandenberg LN, Gerona RR, Kannan K, Taylor JA, van Breemen RB, Dickenson CA, Liao C, Yuan Y, Newbold RR, Padmanabhan V, Vom Saal FS, Woodruff TJ. Erratum to: A round robin approach to the analysis of bisphenol a (BPA) in human blood samples. Environmental Health : a Global Access Science Source. 15: 43. PMID 26956378 DOI: 10.1186/s12940-016-0126-z  0.84
2016 Kataria Y, Deaton RJ, Enk E, Jin M, Petrauskaite M, Dong L, Goldenberg JR, Cotler SJ, Jensen DM, van Breemen RB, Gann PH. Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer. Bmc Gastroenterology. 16: 30. PMID 26927700 DOI: 10.1186/s12876-016-0432-5  1
2016 Hauck ZZ, Feinstein DL, van Breemen RB. LC-MS-MS Analysis of Brodifacoum Isomers in Rat Tissue. Journal of Analytical Toxicology. PMID 26912564 DOI: 10.1093/jat/bkw008  1
2016 Newsome AG, Li Y, van Breemen RB. Improved quantification of free and ester bound gallic acid in food and beverages by UHPLC-MS/MS. Journal of Agricultural and Food Chemistry. PMID 26804199 DOI: 10.1021/acs.jafc.5b04966  1
2016 Imai A, Lankin DC, Nikolić D, Ahn S, van Breemen RB, Farnsworth NR, McAlpine JB, Chen SN, Pauli GF. Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa. Journal of Natural Products. PMID 26760374 DOI: 10.1021/acs.jnatprod.5b00927  1
2016 Hauck ZZ, Huang K, Li G, van Breemen RB. Determination of bisphenol A-glucuronide in human urine using ultrahigh-pressure liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 30: 400-6. PMID 26754133 DOI: 10.1002/rcm.7450  1
2016 Sprouse AA, van Breemen RB. Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 44: 162-71. PMID 26438626 DOI: 10.1124/dmd.115.066902  1
2015 Zhou Q, Chen T, Zhang W, Bozkanat M, Li Y, Xiao L, van Breemen RB, Christman JW, Sznajder JI, Zhou G. Suppression of Von Hippel-Lindau Protein in Fibroblasts Protects Against Bleomycin-induced Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology. PMID 26488390 DOI: 10.1165/rcmb.2015-0111OC  1
2015 Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen SN, Nikolic D, Pauli GF, van Breemen RB, Dietz BM, Bolton JL. Induction of NAD(P)H:quinone oxidoreductase 1 (NQO1) by Glycyrrhiza species used for women's health: differential effects of the Michael acceptors isoliquiritigenin and licochalcone A. Chemical Research in Toxicology. PMID 26473469 DOI: 10.1021/acs.chemrestox.5b00310  1
2015 Gann PH, Deaton RJ, Rueter EE, van Breemen RB, Nonn L, Macias V, Han M, Ananthanarayanan V. A Phase II Randomized Trial of Lycopene-Rich Tomato Extract Among Men with High-Grade Prostatic Intraepithelial Neoplasia. Nutrition and Cancer. 67: 1104-12. PMID 26422197 DOI: 10.1080/01635581.2015.1075560  0.52
2015 Li G, Huang K, Nikolic D, van Breemen RB. High-throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26285764 DOI: 10.1124/dmd.115.065987  1
2015 van Breemen RB. Development of Safe and Effective Botanical Dietary Supplements. Journal of Medicinal Chemistry. 58: 8360-72. PMID 26125082 DOI: 10.1021/acs.jmedchem.5b00417  1
2015 Parvinian A, Casadaban LC, Hauck ZZ, van Breemen RB, Gaba RC. Pharmacokinetic study of conventional sorafenib chemoembolization in a rabbit VX2 liver tumor model. Diagnostic and Interventional Radiology (Ankara, Turkey). 21: 235-40. PMID 25835078 DOI: 10.5152/dir.2014.14394  1
2015 Huang K, Huang L, van Breemen RB. Detection of reactive metabolites using isotope-labeled glutathione trapping and simultaneous neutral loss and precursor ion scanning with ultra-high-pressure liquid chromatography triple quadruple mass spectrometry. Analytical Chemistry. 87: 3646-54. PMID 25774910 DOI: 10.1021/ac504737x  1
2015 Cantuti-Castelvetri L, Maravilla E, Marshall M, Tamayo T, D'auria L, Monge J, Jeffries J, Sural-Fehr T, Lopez-Rosas A, Li G, Garcia K, van Breemen R, Vite C, Garcia J, Bongarzone ER. Mechanism of neuromuscular dysfunction in Krabbe disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 1606-16. PMID 25632136 DOI: 10.1523/JNEUROSCI.2431-14.2015  1
2015 Pituch KC, Moyano AL, Lopez-Rosas A, Marottoli FM, Li G, Hu C, van Breemen R, Månsson JE, Givogri MI. Dysfunction of platelet-derived growth factor receptor α (PDGFRα) represses the production of oligodendrocytes from arylsulfatase A-deficient multipotential neural precursor cells. The Journal of Biological Chemistry. 290: 7040-53. PMID 25605750 DOI: 10.1074/jbc.M115.636498  1
2015 Nikolić D, Lankin DC, Cisowska T, Chen SN, Pauli GF, Van Breemen RB. Nitrogen-containing constituents of black cohosh: Chemistry, structure elucidation, and biological activities The Formation, Structure and Activity of Phytochemicals. 45: 31-75. DOI: 10.1007/978-3-319-20397-3_2  1
2014 Simmler C, Jones T, Anderson JR, Nikoli? DC, van Breemen RB, Soejarto DD, Chen SN, Pauli GF. Species-specific Standardisation of Licorice by Metabolomic Profiling of Flavanones and Chalcones. Phytochemical Analysis : Pca. 25: 378-88. PMID 25859589 DOI: 10.1002/pca.2472  1
2014 Yu LF, Brek Eaton J, Zhang HK, Sabath E, Hanania T, Li GN, van Breemen RB, Whiteaker P, Liu Q, Wu J, Chang YC, Lukas RJ, Brunner D, Kozikowski AP. The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile. Pharmacology Research & Perspectives. 2: e00026. PMID 25505580 DOI: 10.1002/prp2.26  0.84
2014 Ramos Alvarenga RF, Friesen JB, Nikolić D, Simmler C, Napolitano JG, van Breemen R, Lankin DC, McAlpine JB, Pauli GF, Chen SN. K-targeted metabolomic analysis extends chemical subtraction to DESIGNER extracts: selective depletion of extracts of hops (Humulus lupulus). Journal of Natural Products. 77: 2595-604. PMID 25437744 DOI: 10.1021/np500376g  1
2014 Moyano AL, Li G, Lopez-Rosas A, Månsson JE, van Breemen RB, Givogri MI. Distribution of C16:0, C18:0, C24:1, and C24:0 sulfatides in central nervous system lipid rafts by quantitative ultra-high-pressure liquid chromatography tandem mass spectrometry. Analytical Biochemistry. 467: 31-9. PMID 25205652 DOI: 10.1016/j.ab.2014.08.033  1
2014 Simmler C, Nikoli? D, Lankin DC, Yu Y, Friesen JB, van Breemen RB, Lecomte A, Le Quémener C, Audo G, Pauli GF. Orthogonal Analysis Underscores the Relevance of Primary and Secondary Metabolites in Licorice. Journal of Natural Products. PMID 25080313 DOI: 10.1021/np5001945  1
2014 van Breemen RB, Yuan Y, Banuvar S, Shulman LP, Qiu X, Alvarenga RF, Chen SN, Dietz BM, Bolton JL, Pauli GF, Krause E, Viana M, Nikolic D. Pharmacokinetics of prenylated hop phenols in women following oral administration of a standardized extract of hops. Molecular Nutrition & Food Research. 58: 1962-9. PMID 25045111 DOI: 10.1002/mnfr.201400245  1
2014 Newsome AG, Culver CA, van Breemen RB. Nature's palette: the search for natural blue colorants. Journal of Agricultural and Food Chemistry. 62: 6498-511. PMID 24930897 DOI: 10.1021/jf501419q  1
2014 García ME, Nicotra VE, Oberti JC, Ríos-Luci C, León LG, Marler L, Li G, Pezzuto JM, van Breemen RB, Padrón JM, Hueso-Falcón I, Estévez-Braun A. Antiproliferative and quinone reductase-inducing activities of withanolides derivatives. European Journal of Medicinal Chemistry. 82: 68-81. PMID 24878636 DOI: 10.1016/j.ejmech.2014.05.045  1
2014 Krause E, Yuan Y, Hajirahimkhan A, Dong H, Dietz BM, Nikolic D, Pauli GF, Bolton JL, van Breemen RB. Biological and chemical standardization of a hop (Humulus lupulus) botanical dietary supplement. Biomedical Chromatography : Bmc. 28: 729-34. PMID 24861737 DOI: 10.1002/bmc.3177  1
2014 Nikoli? D, Li J, van Breemen RB. Metabolism of Nω -methylserotonin, a serotonergic constituent of black cohosh (Cimicifuga racemosa, L. (Nutt.)), by human liver microsomes. Biomedical Chromatography : Bmc. 28: 1647-51. PMID 24817649 DOI: 10.1002/bmc.3197  1
2014 Vandenberg LN, Gerona RR, Kannan K, Taylor JA, van Breemen RB, Dickenson CA, Liao C, Yuan Y, Newbold RR, Padmanabhan V, Vom Saal FS, Woodruff TJ. A round robin approach to the analysis of bisphenol A (BPA) in human blood samples. Environmental Health : a Global Access Science Source. 13: 25. PMID 24690217 DOI: 10.1186/1476-069X-13-25  1
2014 Karalius VP, Harbison JE, Plange-Rhule J, van Breemen RB, Li G, Huang K, Durazo-Arvizu RA, Mora N, Dugas LR, Vail L, Tuchman NC, Forrester T, Luke A. Bisphenol A (BPA) Found in Humans and Water in Three Geographic Regions with Distinctly Different Levels of Economic Development. Environmental Health Insights. 8: 1-3. PMID 24453495 DOI: 10.4137/EHI.S13130  0.88
2014 Prins GS, Hu WY, Shi GB, Hu DP, Majumdar S, Li G, Huang K, Nelles JL, Ho SM, Walker CL, Kajdacsy-Balla A, van Breemen RB. Bisphenol A promotes human prostate stem-progenitor cell self-renewal and increases in vivo carcinogenesis in human prostate epithelium. Endocrinology. 155: 805-17. PMID 24424067 DOI: 10.1210/en.2013-1955  0.88
2014 Zhuge Y, Yuan Y, van Breemen R, Degrand M, Holian O, Yoder M, Lum H. Stimulated bronchial epithelial cells release bioactive lysophosphatidylcholine 16:0, 18:0, and 18:1. Allergy, Asthma & Immunology Research. 6: 66-74. PMID 24404396 DOI: 10.4168/aair.2014.6.1.66  0.84
2014 Yoder M, Zhuge Y, Yuan Y, Holian O, Kuo S, van Breemen R, Thomas LL, Lum H. Bioactive lysophosphatidylcholine 16:0 and 18:0 are elevated in lungs of asthmatic subjects. Allergy, Asthma & Immunology Research. 6: 61-5. PMID 24404395 DOI: 10.4168/aair.2014.6.1.61  1
2014 Van Loo-Bouwman CA, Naber TH, Minekus M, van Breemen RB, Hulshof PJ, Schaafsma G. Food matrix effects on bioaccessibility of β-carotene can be measured in an in vitro gastrointestinal model. Journal of Agricultural and Food Chemistry. 62: 950-5. PMID 24397305 DOI: 10.1021/jf403312v  1
2014 Yuan Y, Qiu X, Nikolić D, Chen SN, Huang K, Li G, Pauli GF, van Breemen RB. Inhibition of human cytochrome P450 enzymes by hops (Humulus lupulus) and hop prenylphenols. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 53: 55-61. PMID 24342125 DOI: 10.1016/j.ejps.2013.12.003  0.88
2013 Abdelkarim H, Brunsteiner M, Neelarapu R, Bai H, Madriaga A, van Breemen RB, Blond SY, Gaponenko V, Petukhov PA. Photoreactive "nanorulers" detect a novel conformation of full length HDAC3-SMRT complex in solution. Acs Chemical Biology. 8: 2538-49. PMID 24010878 DOI: 10.1021/cb400601g  1
2013 Andreani A, Leoni A, Locatelli A, Morigi R, Rambaldi M, Cervellati R, Greco E, Kondratyuk TP, Park EJ, Huang K, van Breemen RB, Pezzuto JM. Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles. European Journal of Medicinal Chemistry. 68: 412-21. PMID 23994869 DOI: 10.1016/j.ejmech.2013.07.052  1
2013 Eilati E, Hales K, Zhuge Y, Ansenberger Fricano K, Yu R, van Breemen RB, Hales DB. Flaxseed enriched diet-mediated reduction in ovarian cancer severity is correlated to the reduction of prostaglandin E(2) in laying hen ovaries. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 89: 179-87. PMID 23978451 DOI: 10.1016/j.plefa.2013.08.001  1
2013 Dong SH, Cai G, Napolitano JG, Nikolić D, Lankin DC, McAlpine JB, van Breemen RB, Soejarto DD, Pauli GF, Chen SN. Lipidated steroid saponins from Dioscorea villosa (wild yam). Fitoterapia. 91: 113-24. PMID 23968665 DOI: 10.1016/j.fitote.2013.07.018  1
2013 Mo S, Dong L, Hurst WJ, van Breemen RB. Quantitative analysis of phytosterols in edible oils using APCI liquid chromatography-tandem mass spectrometry. Lipids. 48: 949-56. PMID 23884629 DOI: 10.1007/s11745-013-3813-3  1
2013 Hajirahimkhan A, Simmler C, Yuan Y, Anderson JR, Chen SN, Nikolić D, Dietz BM, Pauli GF, van Breemen RB, Bolton JL. Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms. Plos One. 8: e67947. PMID 23874474 DOI: 10.1371/journal.pone.0067947  1
2013 van Breemen RB. Robert J. Cotter (1943-2012). Journal of the American Society For Mass Spectrometry. 24: 655-6. PMID 23536270 DOI: 10.1007/s13361-013-0611-3  1
2013 Yu R, Zhao G, Christman JW, Xiao L, Van Breemen RB. Method development and validation for ultra-high pressure liquid chromatography/tandem mass spectrometry determination of multiple prostanoids in biological samples. Journal of Aoac International. 96: 67-76. PMID 23513960 DOI: 10.5740/jaoacint.12-280  1
2013 Dietz BM, Hagos GK, Eskra JN, Wijewickrama GT, Anderson JR, Nikolic D, Guo J, Wright B, Chen SN, Pauli GF, van Breemen RB, Bolton JL. Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo. Molecular Nutrition & Food Research. 57: 1055-66. PMID 23512484 DOI: 10.1002/mnfr.201200534  1
2013 Gaba RC, Yap FY, Martinez EM, Li Y, Guzman G, Parvinian A, van Breemen RB, Kumar N. Transarterial sorafenib chemoembolization: preliminary study of technical feasibility in a rabbit model. Journal of Vascular and Interventional Radiology : Jvir. 24: 744-50. PMID 23510657 DOI: 10.1016/j.jvir.2013.01.488  1
2013 Qiu X, Yuan Y, Vaishnav A, Tessel MA, Nonn L, van Breemen RB. Effects of lycopene on protein expression in human primary prostatic epithelial cells. Cancer Prevention Research (Philadelphia, Pa.). 6: 419-27. PMID 23483004 DOI: 10.1158/1940-6207.CAPR-12-0364  1
2013 Jana A, Modi KK, Roy A, Anderson JA, van Breemen RB, Pahan K. Up-regulation of neurotrophic factors by cinnamon and its metabolite sodium benzoate: therapeutic implications for neurodegenerative disorders. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 739-55. PMID 23475543 DOI: 10.1007/s11481-013-9447-7  1
2013 Conda-Sheridan M, Park EJ, Beck DE, Reddy PV, Nguyen TX, Hu B, Chen L, White JJ, van Breemen RB, Pezzuto JM, Cushman M. Design, synthesis, and biological evaluation of indenoisoquinoline rexinoids with chemopreventive potential. Journal of Medicinal Chemistry. 56: 2581-605. PMID 23472886 DOI: 10.1021/jm400026k  1
2013 Yuan Y, Yu LF, Qiu X, Kozikowski AP, Van Breemen RB. Pharmacokinetics and brain penetration of LF-3-88, (2-[5-[5-(2(S)-azetidinylmethoxyl)-3-pyridyl]-3-isoxazolyl]ethanol), a selective α4β2-nAChR partial agonist and promising antidepressant Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 912: 38-42. PMID 23246847 DOI: 10.1016/j.jchromb.2012.11.011  1
2013 Zhao G, Yu R, Deng J, Zhao Q, Li Y, Joo M, van Breemen RB, Christman JW, Xiao L. Pivotal role of reactive oxygen species in differential regulation of lipopolysaccharide-induced prostaglandins production in macrophages. Molecular Pharmacology. 83: 167-78. PMID 23071105 DOI: 10.1124/mol.112.080762  1
2013 Kabirov KK, Kapetanovic IM, Benbrook DM, Dinger N, Mankovskaya I, Zakharov A, Detrisac C, Pereira M, Martín-Jiménez T, Onua E, Banerjee A, van Breemen RB, Nikolić D, Chen L, Lyubimov AV. Oral toxicity and pharmacokinetic studies of SHetA2, a new chemopreventive agent, in rats and dogs. Drug and Chemical Toxicology. 36: 284-95. PMID 22947079 DOI: 10.3109/01480545.2012.710632  1
2013 Nikolić D, van Breemen RB. Analytical methods for quantitation of prenylated flavonoids from hops Current Analytical Chemistry. 9: 71-85.  1
2012 Yuan Y, Qiu X, Nikolic D, Dahl JH, van Breemen RB. Method development and validation for ultra-high-pressure LC/MS/MS determination of hop prenylflavonoids in human serum. Journal of Aoac International. 95: 1744-9. PMID 23451393 DOI: 10.5740/jaoacint.11-542  1
2012 Dong SH, Nikolić D, Simmler C, Qiu F, van Breemen RB, Soejarto DD, Pauli GF, Chen SN. Diarylheptanoids from Dioscorea villosa (Wild Yam). Journal of Natural Products. 75: 2168-77. PMID 23245349 DOI: 10.1021/np300603z  1
2012 Vaidya AS, Neelarapu R, Madriaga A, Bai H, Mendonca E, Abdelkarim H, van Breemen RB, Blond SY, Petukhov PA. Novel histone deacetylase 8 ligands without a zinc chelating group: exploring an 'upside-down' binding pose. Bioorganic & Medicinal Chemistry Letters. 22: 6621-7. PMID 23010266 DOI: 10.1016/j.bmcl.2012.08.104  1
2012 Vaidya AS, Karumudi B, Mendonca E, Madriaga A, Abdelkarim H, van Breemen RB, Petukhov PA. Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2. Bioorganic & Medicinal Chemistry Letters. 22: 5025-30. PMID 22771007 DOI: 10.1016/j.bmcl.2012.06.017  1
2012 Zhu H, Lopez-Rosas A, Qiu X, Van Breemen RB, Bongarzone ER. Detection of the neurotoxin psychosine in samples of peripheral blood: application in diagnostics and follow-up of Krabbe disease. Archives of Pathology & Laboratory Medicine. 136: 709-10. PMID 22742542 DOI: 10.5858/arpa.2011-0667-LE  1
2012 Chen L, Conda-Sheridan M, Reddy PV, Morrell A, Park EJ, Kondratyuk TP, Pezzuto JM, van Breemen RB, Cushman M. Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents. Journal of Medicinal Chemistry. 55: 5965-81. PMID 22712432 DOI: 10.1021/jm3006806  1
2012 Baumgarten S, Gaba RC, van Breemen RB. Confirmation of drug delivery after liver chemoembolization: direct tissue doxorubicin measurement by UHPLC-MS-MS. Biomedical Chromatography : Bmc. 26: 1529-33. PMID 22454282 DOI: 10.1002/bmc.2727  1
2012 Kondratyuk TP, Park EJ, Yu R, van Breemen RB, Asolkar RN, Murphy BT, Fenical W, Pezzuto JM. Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents. Marine Drugs. 10: 451-64. PMID 22412812 DOI: 10.3390/md10020451  1
2012 van Breemen RB, Dong L, Pajkovic ND. Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry of Carotenoids. International Journal of Mass Spectrometry. 312: 163-172. PMID 22408388 DOI: 10.1016/j.ijms.2011.07.030  1
2012 Gaba RC, Baumgarten S, Omene BO, van Breemen RB, Garcia KD, Larson AC, Omary RA. Ethiodized oil uptake does not predict doxorubicin drug delivery after chemoembolization in VX2 liver tumors. Journal of Vascular and Interventional Radiology : Jvir. 23: 265-73. PMID 22178040 DOI: 10.1016/j.jvir.2011.10.022  1
2012 Hu C, Nikolic D, Eggler AL, Mesecar AD, van Breemen RB. Screening for natural chemoprevention agents that modify human Keap1. Analytical Biochemistry. 421: 108-14. PMID 22074792 DOI: 10.1016/j.ab.2011.10.028  1
2012 Gödecke T, Yao P, Napolitano JG, Nikolić D, Dietz BM, Bolton JL, van Breemen RB, Farnsworth NR, Chen SN, Lankin DC, Pauli GF. Integrated standardization concept for Angelica botanicals using quantitative NMR. Fitoterapia. 83: 18-32. PMID 21907766 DOI: 10.1016/j.fitote.2011.08.017  1
2012 Kaltashov IA, Van Breemen RB. Special issue honoring Catherine Fenselau International Journal of Mass Spectrometry. 312: 1-4. DOI: 10.1016/j.ijms.2012.01.014  1
2011 Yu R, Xiao L, Zhao G, Christman JW, van Breemen RB. Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2. The Journal of Pharmacology and Experimental Therapeutics. 339: 716-25. PMID 21865441 DOI: 10.1124/jpet.111.185405  1
2011 Li J, Gödecke T, Chen SN, Imai A, Lankin DC, Farnsworth NR, Pauli GF, van Breemen RB, Nikoli? D. In vitro metabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. PMID 21827327 DOI: 10.3109/00498254.2011.603385  1
2011 Kondratyuk TP, Park EJ, Marler LE, Ahn S, Yuan Y, Choi Y, Yu R, van Breemen RB, Sun B, Hoshino J, Cushman M, Jermihov KC, Mesecar AD, Grubbs CJ, Pezzuto JM. Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity. Molecular Nutrition & Food Research. 55: 1249-65. PMID 21714126 DOI: 10.1002/mnfr.201100122  1
2011 Park EJ, Kondratyuk TP, Morrell A, Kiselev E, Conda-Sheridan M, Cushman M, Ahn S, Choi Y, White JJ, van Breemen RB, Pezzuto JM. Induction of retinoid X receptor activity and consequent upregulation of p21WAF1/CIP1 by indenoisoquinolines in MCF7 cells. Cancer Prevention Research (Philadelphia, Pa.). 4: 592-607. PMID 21464033 DOI: 10.1158/1940-6207.CAPR-10-0004  1
2011 van Breemen RB, Sharifi R, Viana M, Pajkovic N, Zhu D, Yuan L, Yang Y, Bowen PE, Stacewicz-Sapuntzakis M. Antioxidant effects of lycopene in African American men with prostate cancer or benign prostate hyperplasia: a randomized, controlled trial. Cancer Prevention Research (Philadelphia, Pa.). 4: 711-8. PMID 21430075 DOI: 10.1158/1940-6207.CAPR-10-0288  1
2011 Hu C, Eggler AL, Mesecar AD, van Breemen RB. Modification of keap1 cysteine residues by sulforaphane. Chemical Research in Toxicology. 24: 515-21. PMID 21391649 DOI: 10.1021/tx100389r  1
2011 Yang JH, Kondratyuk TP, Jermihov KC, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Huang R, Liu Y, Wang LQ, Mesecar AD, van Breemen RB, Pezzuto JM, et al. Bioactive compounds from the fern Lepisorus contortus. Journal of Natural Products. 74: 129-36. PMID 21261296 DOI: 10.1021/np100373f  1
2011 Choi Y, Jermihov K, Nam SJ, Sturdy M, Maloney K, Qiu X, Chadwick LR, Main M, Chen SN, Mesecar AD, Farnsworth NR, Pauli GF, Fenical W, Pezzuto JM, van Breemen RB, ... van Breemen RR, et al. Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS. Analytical Chemistry. 83: 1048-52. PMID 21192729 DOI: 10.1021/ac1028424  1
2011 Chen SN, Friesen JB, Webster D, Nikolic D, van Breemen RB, Wang ZJ, Fong HH, Farnsworth NR, Pauli GF. Phytoconstituents from Vitex agnus-castus fruits. Fitoterapia. 82: 528-33. PMID 21163339 DOI: 10.1016/j.fitote.2010.12.003  1
2011 van Breemen RB, Tao Y, Li W. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia. 82: 38-43. PMID 20837112 DOI: 10.1016/j.fitote.2010.09.004  1
2011 Cao H, Yu R, Tao Y, Nikolic D, van Breemen RB. Measurement of cyclooxygenase inhibition using liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 54: 230-5. PMID 20817448 DOI: 10.1016/j.jpba.2010.08.001  1
2010 Dong L, Shion H, Davis RG, Terry-Penak B, Castro-Perez J, van Breemen RB. Collision cross-section determination and tandem mass spectrometric analysis of isomeric carotenoids using electrospray ion mobility time-of-flight mass spectrometry. Analytical Chemistry. 82: 9014-21. PMID 20939506 DOI: 10.1021/ac101974g  1
2010 Guo J, Peng D, Dai Q, Liao S, Wright BJ, van Breemen RB. Quantitative analysis of 3alpha,6alpha,24-trihydroxy-24,24-di(trifluoromethyl)-5beta-cholane, a potent synthetic steroidal liver X receptor agonist in plasma using liquid chromatography-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 1885-8. PMID 20627826 DOI: 10.1016/j.jchromb.2010.05.009  1
2010 Hoshino J, Park EJ, Kondratyuk TP, Marler L, Pezzuto JM, van Breemen RB, Mo S, Li Y, Cushman M. Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. Journal of Medicinal Chemistry. 53: 5033-43. PMID 20527891 DOI: 10.1021/jm100274c  1
2010 Wang Z, Chandrasena ER, Yuan Y, Peng KW, van Breemen RB, Thatcher GR, Bolton JL. Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens. Chemical Research in Toxicology. 23: 1365-73. PMID 20509668 DOI: 10.1021/tx1001282  1
2010 Dahl JH, van Breemen RB. Rapid quantitative analysis of 8-iso-prostaglandin-F(2alpha) using liquid chromatography-tandem mass spectrometry and comparison with an enzyme immunoassay method. Analytical Biochemistry. 404: 211-6. PMID 20507827 DOI: 10.1016/j.ab.2010.05.023  1
2010 Bolca S, Li J, Nikolic D, Roche N, Blondeel P, Possemiers S, De Keukeleire D, Bracke M, Heyerick A, van Breemen RB, Depypere H. Disposition of hop prenylflavonoids in human breast tissue. Molecular Nutrition & Food Research. 54: S284-94. PMID 20486208 DOI: 10.1002/mnfr.200900519  0.88
2010 Cao H, Yu R, Choi Y, Ma ZZ, Zhang H, Xiang W, Lee DY, Berman BM, Moudgil KD, Fong HH, van Breemen RB. Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation. Pharmacological Research. 61: 519-24. PMID 20188172 DOI: 10.1016/j.phrs.2010.02.007  1
2010 Van Loo-Bouwman CA, Naber TH, van Breemen RB, Zhu D, Dicke H, Siebelink E, Hulshof PJ, Russel FG, Schaafsma G, West CE. Vitamin A equivalency and apparent absorption of beta-carotene in ileostomy subjects using a dual-isotope dilution technique. The British Journal of Nutrition. 103: 1836-43. PMID 20132586 DOI: 10.1017/S0007114509993849  1
2010 Yang JH, Kondratyuk TP, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Pegan S, Liu Y, Wang LQ, Mesecar AD, Van Breemen RB, Pezzuto JM, Fong HH, et al. Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata. Phytochemistry. 71: 641-7. PMID 20100622 DOI: 10.1016/j.phytochem.2010.01.002  0.6
2010 Cuendet M, Guo J, Luo Y, Chen S, Oteham CP, Moon RC, van Breemen RB, Marler LE, Pezzuto JM. Cancer chemopreventive activity and metabolism of isoliquiritigenin, a compound found in licorice. Cancer Prevention Research (Philadelphia, Pa.). 3: 221-32. PMID 20068129 DOI: 10.1158/1940-6207.CAPR-09-0049  1
2010 van Breemen RB, Liang W, Banuvar S, Shulman LP, Pang Y, Tao Y, Nikolic D, Krock KM, Fabricant DS, Chen SN, Hedayat S, Bolton JL, Pauli GF, Piersen CE, Krause EC, et al. Pharmacokinetics of 23-epi-26-deoxyactein in women after oral administration of a standardized extract of black cohosh. Clinical Pharmacology and Therapeutics. 87: 219-25. PMID 20032972 DOI: 10.1038/clpt.2009.251  1
2010 Koch D, Johnson L, Gehrke CW, Sandra P, Van Breemen RB. Chromatography-Advances in Environmental and Natural Products, Chemical Analysis and Synthesis Chromatography: a Science of Discovery. 345-359. DOI: 10.1002/9780470555729.ch9  1
2009 Tao Y, Li W, Liang W, Van Breemen RB. Identification and quantification of gingerols and related compounds in ginger dietary supplements using high-performance liquid chromatography-tandem mass spectrometry. Journal of Agricultural and Food Chemistry. 57: 10014-21. PMID 19817455 DOI: 10.1021/jf9020224  1
2009 Geller SE, Shulman LP, van Breemen RB, Banuvar S, Zhou Y, Epstein G, Hedayat S, Nikolic D, Krause EC, Piersen CE, Bolton JL, Pauli GF, Farnsworth NR. Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms: a randomized controlled trial. Menopause (New York, N.Y.). 16: 1156-66. PMID 19609225 DOI: 10.1097/gme.0b013e3181ace49b  1
2009 Calderón AI, Wright BJ, Hurst WJ, van Breemen RB. Screening antioxidants using LC-MS: case study with cocoa. Journal of Agricultural and Food Chemistry. 57: 5693-9. PMID 19489609 DOI: 10.1021/jf9014203  1
2009 Gödecke T, Lankin DC, Nikolic D, Chen SN, van Breemen RB, Farnsworth NR, Pauli GF. Guanidine alkaloids and Pictet-Spengler adducts from black cohosh (Cimicifuga racemosa). Journal of Natural Products. 72: 433-7. PMID 19220011 DOI: 10.1021/np8006952  1
2009 Wang Z, Wijewickrama GT, Peng KW, Dietz BM, Yuan L, van Breemen RB, Bolton JL, Thatcher GR. Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus. The Journal of Biological Chemistry. 284: 8633-42. PMID 19158089 DOI: 10.1074/jbc.M807860200  1
2009 Gödecke T, Nikolic D, Lankin DC, Chen SN, Powell SL, Dietz B, Bolton JL, van Breemen RB, Farnsworth NR, Pauli GF. Phytochemistry of cimicifugic acids and associated bases in Cimicifuga racemosa root extracts. Phytochemical Analysis : Pca. 20: 120-33. PMID 19140115 DOI: 10.1002/pca.1106  1
2009 Van Loo-Bouwman CA, West CE, van Breemen RB, Zhu D, Siebelink E, Versloot P, Hulshof PJ, van Lieshout M, Russel FG, Schaafsma G, Naber TH. Vitamin A equivalency of beta-carotene in healthy adults: limitation of the extrinsic dual-isotope dilution technique to measure matrix effect. The British Journal of Nutrition. 101: 1837-45. PMID 19025719 DOI: 10.1017/S0007114508131762  1
2009 Qin Z, Kastrati I, Ashgodom RT, Lantvit DD, Overk CR, Choi Y, van Breemen RB, Bolton JL, Thatcher GR. Structural modulation of oxidative metabolism in design of improved benzothiophene selective estrogen receptor modulators. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 161-9. PMID 18936111 DOI: 10.1124/dmd.108.023408  1
2008 Powell SL, Gödecke T, Nikolic D, Chen SN, Ahn S, Dietz B, Farnsworth NR, van Breemen RB, Lankin DC, Pauli GF, Bolton JL. In vitro serotonergic activity of black cohosh and identification of N(omega)-methylserotonin as a potential active constituent. Journal of Agricultural and Food Chemistry. 56: 11718-26. PMID 19049296 DOI: 10.1021/jf803298z  1
2008 Dietz BM, Liu D, Hagos GK, Yao P, Schinkovitz A, Pro SM, Deng S, Farnsworth NR, Pauli GF, van Breemen RB, Bolton JL. Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1. Chemical Research in Toxicology. 21: 1939-48. PMID 18808158 DOI: 10.1021/tx8001274  1
2008 Ding S, Wang Y, Kolbanovskiy A, Durandin A, Bolton JL, van Breemen RB, Broyde S, Geacintov NE. Determination of absolute configurations of 4-hydroxyequilenin-cytosine and -adenine adducts by optical rotatory dispersion, electronic circular dichroism, density functional theory calculations, and mass spectrometry. Chemical Research in Toxicology. 21: 1739-48. PMID 18680315 DOI: 10.1021/tx800095f  1
2008 Guo J, Liu A, Cao H, Luo Y, Pezzuto JM, van Breemen RB. Biotransformation of the chemopreventive agent 2',4',4-trihydroxychalcone (isoliquiritigenin) by UDP-glucuronosyltransferases. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2104-12. PMID 18653743 DOI: 10.1124/dmd.108.021857  1
2008 Overk CR, Guo J, Chadwick LR, Lantvit DD, Minassi A, Appendino G, Chen SN, Lankin DC, Farnsworth NR, Pauli GF, van Breemen RB, Bolton JL. In vivo estrogenic comparisons of Trifolium pratense (red clover) Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin. Chemico-Biological Interactions. 176: 30-9. PMID 18619951 DOI: 10.1016/j.cbi.2008.06.005  1
2008 van Breemen RB, Pajkovic N. Multitargeted therapy of cancer by lycopene. Cancer Letters. 269: 339-51. PMID 18585855 DOI: 10.1016/j.canlet.2008.05.016  1
2008 van Breemen RB, Fong HH, Farnsworth NR. Ensuring the safety of botanical dietary supplements. The American Journal of Clinical Nutrition. 87: 509S-13S. PMID 18258648  1
2008 Farnsworth NR, Krause EC, Bolton JL, Pauli GF, van Breemen RB, Graham JG. The University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements Research for Women's Health: from plant to clinical use. The American Journal of Clinical Nutrition. 87: 504S-8S. PMID 18258647  1
2008 Barnes S, Birt DF, Cassileth BR, Cefalu WT, Chilton FH, Farnsworth NR, Raskin I, van Breemen RB, Weaver CM. Technologies and experimental approaches at the National Institutes of Health Botanical Research Centers. The American Journal of Clinical Nutrition. 87: 476S-80S. PMID 18258642  1
2008 Chen SN, Turner A, Jaki BU, Nikolic D, van Breemen RB, Friesen JB, Pauli GF. An experimental implementation of chemical subtraction. Journal of Pharmaceutical and Biomedical Analysis. 46: 692-8. PMID 18234463 DOI: 10.1016/j.jpba.2007.12.014  1
2008 Choi Y, van Breemen RB. Development of a screening assay for ligands to the estrogen receptor based on magnetic microparticles and LC-MS. Combinatorial Chemistry & High Throughput Screening. 11: 1-6. PMID 18220538 DOI: 10.2174/138620708783398340  1
2008 Guo J, Liu D, Nikolic D, Zhu D, Pezzuto JM, van Breemen RB. In vitro metabolism of isoliquiritigenin by human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 461-8. PMID 18006650 DOI: 10.1124/dmd.107.018721  1
2008 Cao H, Xiao L, Park G, Wang X, Azim AC, Christman JW, van Breemen RB. An improved LC-MS/MS method for the quantification of prostaglandins E(2) and D(2) production in biological fluids. Analytical Biochemistry. 372: 41-51. PMID 17976507 DOI: 10.1016/j.ab.2007.08.041  1
2008 Van Breemen RB. Editorial from editor-in-chief Combinatorial Chemistry and High Throughput Screening. 11: 83. DOI: 10.2174/138620708783744534  1
2008 Eggler AL, Luo Y, Van Breemen RB, Mesecar AD. Identification of the highly reactive cysteine 151 in the chemopreventive agent-sensor Keap1 protein is method-dependent (Chemical Research in Toxicology (2007) 20, 12, (1878-1884)) Chemical Research in Toxicology. 21: 556. DOI: 10.1021/tx800015c  1
2007 Goo YA, Li Z, Pajkovic N, Shaffer S, Taylor G, Chen J, Campbell D, Arnstein L, Goodlett DR, van Breemen RB. Systematic investigation of lycopene effects in LNCaP cells by use of novel large-scale proteomic analysis software. Proteomics. Clinical Applications. 1: 513-523. PMID 20740054 DOI: 10.1002/prca.200600511  1
2007 Azim AC, Wang X, Park GY, Sadikot RT, Cao H, Mathew B, Atchison M, van Breemen RB, Joo M, Christman JW. NF-kappaB-inducing kinase regulates cyclooxygenase 2 gene expression in macrophages by phosphorylation of PU.1. Journal of Immunology (Baltimore, Md. : 1950). 179: 7868-75. PMID 18025233 DOI: 10.4049/JIMMUNOL.179.11.7868  0.84
2007 Luo Y, Eggler AL, Liu D, Liu G, Mesecar AD, van Breemen RB. Sites of alkylation of human Keap1 by natural chemoprevention agents. Journal of the American Society For Mass Spectrometry. 18: 2226-32. PMID 17980616 DOI: 10.1016/j.jasms.2007.09.015  1
2007 Eggler AL, Luo Y, van Breemen RB, Mesecar AD. Identification of the highly reactive cysteine 151 in the chemopreventive agent-sensor Keap1 protein is method-dependent. Chemical Research in Toxicology. 20: 1878-84. PMID 17935299 DOI: 10.1021/tx700217c  1
2007 Pang Y, Nikolic D, Zhu D, Chadwick LR, Pauli GF, Farnsworth NR, van Breemen RB. Binding of the hop (Humulus lupulus L.) chalcone xanthohumol to cytosolic proteins in Caco-2 intestinal epithelial cells. Molecular Nutrition & Food Research. 51: 872-9. PMID 17579893 DOI: 10.1002/mnfr.200600252  1
2007 Azim AC, Cao H, Gao X, Joo M, Malik AB, van Breemen RB, Sadikot RT, Park G, Christman JW. Regulation of cyclooxygenase-2 expression by small GTPase Rac2 in bone marrow macrophages. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L668-73. PMID 17575012 DOI: 10.1152/ajplung.00043.2007  0.84
2007 Chen SN, Lankin DC, Nikolic D, Fabricant DS, Lu ZZ, Ramirez B, van Breemen RB, Fong HH, Farnsworth NR, Pauli GF. Chlorination diversifies Cimicifuga racemosa triterpene glycosides. Journal of Natural Products. 70: 1016-23. PMID 17555351 DOI: 10.1021/np0700319  1
2007 van Breemen RB, Fong HH, Farnsworth NR. The role of quality assurance and standardization in the safety of botanical dietary supplements. Chemical Research in Toxicology. 20: 577-82. PMID 17362032 DOI: 10.1021/tx7000493  1
2007 Turner A, Chen SN, Nikolic D, van Breemen R, Farnsworth NR, Pauli GF. Coumaroyl iridoids and a depside from cranberry (Vaccinium macrocarpon). Journal of Natural Products. 70: 253-8. PMID 17269823 DOI: 10.1021/np060260f  1
2007 Mathew B, Park GY, Cao H, Azim AC, Wang X, Van Breemen RB, Sadikot RT, Christman JW. Inhibitory kappaB kinase 2 activates airway epithelial cells to stimulate bone marrow macrophages. American Journal of Respiratory Cell and Molecular Biology. 36: 562-72. PMID 17204585 DOI: 10.1165/rcmb.2006-0245OC  1
2006 Deng S, Chen SN, Lu J, Wang ZJ, Nikolic D, van Breemen RB, Santarsiero BD, Mesecar A, Fong HH, Farnsworth NR, Pauli GF. GABAergic phthalide dimers from Angelica sinensis (Oliv.) Diels. Phytochemical Analysis : Pca. 17: 398-405. PMID 17144247 DOI: 10.1002/pca.937  1
2006 Wang Z, Yuan H, Nikolic D, Van Breemen RB, Silverman RB. (+/-)-(1S,2R,5S)-5-Amino-2-fluorocyclohex-3-enecarboxylic acid. A potent GABA aminotransferase inactivator that irreversibly inhibits via an elimination-aromatization pathway. Biochemistry. 45: 14513-22. PMID 17128990 DOI: 10.1021/bi061592m  1
2006 Liu A, Pajkovic N, Pang Y, Zhu D, Calamini B, Mesecar AL, van Breemen RB. Absorption and subcellular localization of lycopene in human prostate cancer cells. Molecular Cancer Therapeutics. 5: 2879-85. PMID 17121935 DOI: 10.1158/1535-7163.MCT-06-0373  1
2006 Melse-Boonstra A, Verhoef P, West CE, van Rhijn JA, van Breemen RB, Lasaroms JJ, Garbis SD, Katan MB, Kok FJ. A dual-isotope-labeling method of studying the bioavailability of hexaglutamyl folic acid relative to that of monoglutamyl folic acid in humans by using multiple orally administered low doses. The American Journal of Clinical Nutrition. 84: 1128-33. PMID 17093166 DOI: 10.1093/ajcn/84.5.1128  1
2006 Kapetanovic IM, Krishnaraj R, Martin-Jimenez T, Yuan L, van Breemen RB, Lyubimov A. Effects of oral dosing paradigms (gavage versus diet) on pharmacokinetics and pharmacodynamics. Chemico-Biological Interactions. 164: 68-75. PMID 17027946 DOI: 10.1016/j.cbi.2006.08.019  1
2006 Zhu D, Wang Y, Pang Y, Liu A, Guo J, Bouwman CA, West CE, van Breemen RB. Quantitative analyses of beta-carotene and retinol in serum and feces in support of clinical bioavailability studies. Rapid Communications in Mass Spectrometry : Rcm. 20: 2427-32. PMID 16841362 DOI: 10.1002/rcm.2601  1
2006 Nikolic D, Li Y, Chadwick LR, van Breemen RB. In vitro studies of intestinal permeability and hepatic and intestinal metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus L.). Pharmaceutical Research. 23: 864-72. PMID 16715376 DOI: 10.1007/s11095-006-9902-8  1
2006 Mallavadhani UV, Narasimhan K, Sudhakar AV, Mahapatra A, Li W, van Breemen RB. Three new pentacyclic triterpenes and some flavonoids from the fruits of an Indian Ayurvedic plant Dendrophthoe falcata and their estrogen receptor binding activity. Chemical & Pharmaceutical Bulletin. 54: 740-4. PMID 16651782 DOI: JST.JSTAGE/cpb/54.740  1
2006 Deng S, Chen SN, Yao P, Nikolic D, van Breemen RB, Bolton JL, Fong HH, Farnsworth NR, Pauli GF. Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. Journal of Natural Products. 69: 536-41. PMID 16643021 DOI: 10.1021/np050301s  1
2006 Guo J, Nikolic D, Chadwick LR, Pauli GF, van Breemen RB. Identification of human hepatic cytochrome P450 enzymes involved in the metabolism of 8-prenylnaringenin and isoxanthohumol from hops (Humulus lupulus L.). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1152-9. PMID 16611861 DOI: 10.1124/dmd.105.008250  1
2006 Booth NL, Overk CR, Yao P, Burdette JE, Nikolic D, Chen SN, Bolton JL, van Breemen RB, Pauli GF, Farnsworth NR. The chemical and biologic profile of a red clover (Trifolium pratense L.) phase II clinical extract. Journal of Alternative and Complementary Medicine (New York, N.Y.). 12: 133-9. PMID 16566672 DOI: 10.1089/acm.2006.12.133  1
2006 Van Breemen RB. Combinatorial Chemistry & High Throughput Screening: Editorial Combinatorial Chemistry and High Throughput Screening. 9: 1. DOI: 10.2174/138620706775213877  1
2005 van Breemen RB, Li Y. Caco-2 cell permeability assays to measure drug absorption. Expert Opinion On Drug Metabolism & Toxicology. 1: 175-85. PMID 16922635 DOI: 10.1517/17425255.1.2.175  1
2005 Cheng X, van Breemen RB. Mass spectrometry-based screening for inhibitors of beta-amyloid protein aggregation. Analytical Chemistry. 77: 7012-5. PMID 16255603 DOI: 10.1021/ac050556a  1
2005 Li Y, Yang X, van Breemen RB, Bolton JL. Characterization of two new variants of human catechol O-methyltransferase in vitro. Cancer Letters. 230: 81-9. PMID 16253764 DOI: 10.1016/j.canlet.2004.12.022  1
2005 Liu G, Eggler AL, Dietz BM, Mesecar AD, Bolton JL, Pezzuto JM, van Breemen RB. Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1. Analytical Chemistry. 77: 6407-14. PMID 16194107 DOI: 10.1021/ac050892r  1
2005 Liu J, Li Q, Yang X, van Breemen RB, Bolton JL, Thatcher GR. Analysis of protein covalent modification by xenobiotics using a covert oxidatively activated tag: raloxifene proof-of-principle study. Chemical Research in Toxicology. 18: 1485-96. PMID 16167842 DOI: 10.1021/tx0501738  1
2005 Fabricant DS, Nikolic D, Lankin DC, Chen SN, Jaki BU, Krunic A, van Breemen RB, Fong HH, Farnsworth NR, Pauli GF. Cimipronidine, a cyclic guanidine alkaloid from Cimicifuga racemosa. Journal of Natural Products. 68: 1266-70. PMID 16124775 DOI: 10.1021/np050066d  1
2005 Dietz BM, Kang YH, Liu G, Eggler AL, Yao P, Chadwick LR, Pauli GF, Farnsworth NR, Mesecar AD, van Breemen RB, Bolton JL. Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase. Chemical Research in Toxicology. 18: 1296-305. PMID 16097803 DOI: 10.1021/tx050058x  1
2005 Overk CR, Yao P, Chadwick LR, Nikolic D, Sun Y, Cuendet MA, Deng Y, Hedayat AS, Pauli GF, Farnsworth NR, van Breemen RB, Bolton JL. Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense). Journal of Agricultural and Food Chemistry. 53: 6246-53. PMID 16076101 DOI: 10.1021/jf050448p  1
2005 van Breemen RB. How do intermediate endpoint markers respond to lycopene in men with prostate cancer or benign prostate hyperplasia? The Journal of Nutrition. 135: 2062S-4S. PMID 16046743  1
2005 Eggler AL, Liu G, Pezzuto JM, van Breemen RB, Mesecar AD. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proceedings of the National Academy of Sciences of the United States of America. 102: 10070-5. PMID 16006525 DOI: 10.1073/pnas.0502402102  1
2005 Li Y, Yang X, Chang M, Yager JD, van Breemen RB, Bolton JL. Functional and structural comparisons of cysteine residues in the Val108 wild type and Met108 variant of human soluble catechol O-methyltransferase. Chemico-Biological Interactions. 152: 151-63. PMID 15840388 DOI: 10.1016/j.cbi.2005.03.001  1
2005 Constantinou AI, White BE, Tonetti D, Yang Y, Liang W, Li W, van Breemen RB. The soy isoflavone daidzein improves the capacity of tamoxifen to prevent mammary tumours. European Journal of Cancer (Oxford, England : 1990). 41: 647-54. PMID 15737570 DOI: 10.1016/j.ejca.2004.12.005  1
2005 Liu J, Liu H, van Breemen RB, Thatcher GR, Bolton JL. Bioactivation of the selective estrogen receptor modulator acolbifene to quinone methides. Chemical Research in Toxicology. 18: 174-82. PMID 15720121 DOI: 10.1021/tx0497752  1
2005 Liu H, Liu J, van Breemen RB, Thatcher GR, Bolton JL. Bioactivation of the selective estrogen receptor modulator desmethylated arzoxifene to quinoids: 4'-fluoro substitution prevents quinoid formation. Chemical Research in Toxicology. 18: 162-73. PMID 15720120 DOI: 10.1021/tx049776u  1
2005 Sun Y, Li W, Fitzloff JF, van Breemen RB. Liquid chromatography/electrospray tandem mass spectrometry of terpenoid lactones in Ginkgo biloba. Journal of Mass Spectrometry : Jms. 40: 373-9. PMID 15712369 DOI: 10.1002/jms.795  1
2005 Nikolic D, Li Y, Chadwick LR, Pauli GF, van Breemen RB. Metabolism of xanthohumol and isoxanthohumol, prenylated flavonoids from hops (Humulus lupulus L.), by human liver microsomes. Journal of Mass Spectrometry : Jms. 40: 289-99. PMID 15712367 DOI: 10.1002/jms.753  1
2005 Sun Y, Gu C, Liu X, Liang W, Yao P, Bolton JL, van Breemen RB. Ultrafiltration tandem mass spectrometry of estrogens for characterization of structure and affinity for human estrogen receptors. Journal of the American Society For Mass Spectrometry. 16: 271-9. PMID 15694777 DOI: 10.1016/j.jasms.2004.11.002  1
2005 Zhu Y, Nikolic D, Van Breemen RB, Silverman RB. Mechanism of inactivation of inducible nitric oxide synthase by amidines. Irreversible enzyme inactivation without inactivator modification. Journal of the American Chemical Society. 127: 858-68. PMID 15656623 DOI: 10.1021/ja0445645  1
2005 Kobayashi T, Yang X, Walker LA, Van Breemen RB, Solaro RJ. A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: Identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C Journal of Molecular and Cellular Cardiology. 38: 213-218. PMID 15623438 DOI: 10.1016/j.yjmcc.2004.10.014  1
2005 Van Breemen RB. Combinatorial Chemistry and High Throughput Screening: Editorial from editor-in-chief Combinatorial Chemistry and High Throughput Screening. 8: 1-2. DOI: 10.2174/1386207053328200  1
2004 Chadwick LR, Nikolic D, Burdette JE, Overk CR, Bolton JL, van Breemen RB, Fröhlich R, Fong HH, Farnsworth NR, Pauli GF. Estrogens and congeners from spent hops (Humulus lupulus). Journal of Natural Products. 67: 2024-32. PMID 15620245 DOI: 10.1021/np049783i  1
2004 Booth NL, Nikolic D, van Breemen RB, Geller SE, Banuvar S, Shulman LP, Farnsworth NR. Confusion regarding anticoagulant coumarins in dietary supplements. Clinical Pharmacology and Therapeutics. 76: 511-6. PMID 15592321 DOI: 10.1016/j.clpt.2004.08.023  1
2004 Mariappan SV, Cheng X, van Breemen RB, Silks LA, Gupta G. Analysis of GAA/TTC DNA triplexes using nuclear magnetic resonance and electrospray ionization mass spectrometry. Analytical Biochemistry. 334: 216-26. PMID 15494127 DOI: 10.1016/j.ab.2004.07.036  1
2004 Li Y, Grubjesic S, Nikolic D, Zhu D, Kosmeder JW, Moriarty RM, Pezzuto JM, Van Breemen RB. In vitro assessment of intestinal permeability and hepatic metabolism of 4'-bromoflavone, a promising cancer chemopreventive agent. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 34: 535-47. PMID 15277014 DOI: 10.1080/00498250410001713159  1
2004 Yu L, Liu H, Li W, Zhang F, Luckie C, van Breemen RB, Thatcher GR, Bolton JL. Oxidation of raloxifene to quinoids: potential toxic pathways via a diquinone methide and o-quinones. Chemical Research in Toxicology. 17: 879-88. PMID 15257612 DOI: 10.1021/tx0342722  1
2004 Piersen CE, Booth NL, Sun Y, Liang W, Burdette JE, van Breemen RB, Geller SE, Gu C, Banuvar S, Shulman LP, Bolton JL, Farnsworth NR. Chemical and biological characterization and clinical evaluation of botanical dietary supplements: a phase I red clover extract as a model. Current Medicinal Chemistry. 11: 1361-74. PMID 15180571  1
2004 Li Y, Yao J, Chang M, Nikolic D, Yu L, Yager JD, Mesecar AD, van Breemen RB, Bolton JL. Equine catechol estrogen 4-hydroxyequilenin is a more potent inhibitor of the variant form of catechol-O-methyltransferase. Chemical Research in Toxicology. 17: 512-20. PMID 15089093 DOI: 10.1021/tx0342464  1
2004 Nikolic D, van Breemen RB. New metabolic pathways for flavanones catalyzed by rat liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 387-97. PMID 15039291 DOI: 10.1124/dmd.32.4.387  1
2004 Yang X, Wu H, Kobayashi T, Solaro RJ, van Breemen RB. Enhanced ionization of phosphorylated peptides during MALDI TOF mass spectrometry. Analytical Chemistry. 76: 1532-6. PMID 14987115 DOI: 10.1021/ac035203v  1
2004 Liu J, Burdette JE, Sun Y, Deng S, Schlecht SM, Zheng W, Nikolic D, Mahady G, van Breemen RB, Fong HH, Pezzuto JM, Bolton JL, Farnsworth NR. Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry). Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 11: 18-23. PMID 14974442 DOI: 10.1078/0944-7113-00331  1
2004 Nikolic D, Li Y, Chadwick LR, Grubjesic S, Schwab P, Metz P, van Breemen RB. Metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 272-9. PMID 14744951 DOI: 10.1124/dmd.32.2.272  1
2004 Singletary KW, Barnes SL, van Breemen RB. Ethanol inhibits benzo[a]pyrene-DNA adduct removal and increases 8-oxo-deoxyguanosine formation in human mammary epithelial cells. Cancer Letters. 203: 139-44. PMID 14732221 DOI: 10.1016/j.canlet.2003.09.004  1
2004 Li W, Sun Y, Van Breemen RB, Fitzloff JF. Evaluation of major caffeic acid derivatives in Echinacea purpurea dietary supplements by HPLC with photodiode array detection and electrospray mass spectrometry Journal of Liquid Chromatography and Related Technologies. 27: 2507-2529. DOI: 10.1081/JLC-200028369  1
2004 Van Breemen RB. Combinatorial Chemistry and High Throughput Screening: Preface Combinatorial Chemistry and High Throughput Screening. 7.  1
2003 Li Y, Shin YG, Yu C, Kosmeder JW, Hirschelman WH, Pezzuto JM, van Breemen RB. Increasing the throughput and productivity of Caco-2 cell permeability assays using liquid chromatography-mass spectrometry: application to resveratrol absorption and metabolism. Combinatorial Chemistry & High Throughput Screening. 6: 757-67. PMID 14683481 DOI: 10.2174/138620703771826865  1
2003 Singletary KW, Stansbury MJ, Giusti M, Van Breemen RB, Wallig M, Rimando A. Inhibition of rat mammary tumorigenesis by concord grape juice constituents. Journal of Agricultural and Food Chemistry. 51: 7280-6. PMID 14640571 DOI: 10.1021/jf030278l  1
2003 Lu X, Nikolic D, Mitchell DJ, van Breemen RB, Mersfelder JA, Hille R, Silverman RB. A mechanism for substrate-Induced formation of 6-hydroxyflavin mononucleotide catalyzed by C30A trimethylamine dehydrogenase. Bioorganic & Medicinal Chemistry Letters. 13: 4129-32. PMID 14592522 DOI: 10.1016/j.bmcl.2003.07.032  1
2003 Lyons MM, Yu C, Toma RB, Cho SY, Reiboldt W, Lee J, van Breemen RB. Resveratrol in raw and baked blueberries and bilberries. Journal of Agricultural and Food Chemistry. 51: 5867-70. PMID 13129286 DOI: 10.1021/jf034150f  1
2003 Cheng X, Shin YG, Levine BS, Smith AC, Tomaszewski JE, van Breemen RB. Quantitative analysis of betulinic acid in mouse, rat and dog plasma using electrospray liquid chromatography/mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 17: 2089-92. PMID 12955738 DOI: 10.1002/rcm.1155  1
2003 Burdette JE, Liu J, Chen SN, Fabricant DS, Piersen CE, Barker EL, Pezzuto JM, Mesecar A, Van Breemen RB, Farnsworth NR, Bolton JL. Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor. Journal of Agricultural and Food Chemistry. 51: 5661-70. PMID 12952416 DOI: 10.1021/jf034264r  1
2003 Su BN, Park EJ, Nikolic D, Schunke Vigo J, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora. Journal of Natural Products. 66: 1089-93. PMID 12932130 DOI: 10.1021/np030081n  1
2003 Van Lieshout M, West CE, Van De Bovenkamp P, Wang Y, Sun Y, Van Breemen RB, Muhilal DP, Verhoeven MA, Creemers AF, Lugtenburg J. Extraction of carotenoids from feces, enabling the bioavailability of beta-carotene to be studied in Indonesian children. Journal of Agricultural and Food Chemistry. 51: 5123-30. PMID 12903979 DOI: 10.1021/jf0300240  1
2003 Kouloumbos VN, Tsipi DF, Hiskia AE, Nikolic D, van Breemen RB. Identification of photocatalytic degradation products of diazinon in TiO2 aqueous suspensions using GC/MS/MS and LC/MS with quadrupole time-of-flight mass spectrometry. Journal of the American Society For Mass Spectrometry. 14: 803-17. PMID 12892905 DOI: 10.1016/S1044-0305(03)00333-7  1
2003 Johnson BM, Van Breemen RB. In vitro formation of quinoid metabolites of the dietary supplement Cimicifuga racemosa (black cohosh) Chemical Research in Toxicology. 16: 838-846. PMID 12870886  1
2003 Liu X, Zhang F, Liu H, Burdette JE, Li Y, Overk CR, Pisha E, Yao J, van Breemen RB, Swanson SM, Bolton JL. Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin. Chemical Research in Toxicology. 16: 741-9. PMID 12807357 DOI: 10.1021/tx030001f  1
2003 Johnson BM, Qiu SX, Zhang S, Zhang F, Burdette JE, Yu L, Bolton JL, van Breemen RB. Identification of novel electrophilic metabolites of piper methysticum Forst (Kava). Chemical Research in Toxicology. 16: 733-40. PMID 12807356 DOI: 10.1021/tx020113r  1
2003 Yao J, Li Y, Chang M, Wu H, Yang X, Goodman JE, Liu X, Liu H, Mesecar AD, Van Breemen RB, Yager JD, Bolton JL. Catechol estrogen 4-hydroxyequilenin is a substrate and an inhibitor of catechol-O-methyltransferase. Chemical Research in Toxicology. 16: 668-75. PMID 12755597 DOI: 10.1021/tx0340549  1
2003 Gu JQ, Li W, Kang YH, Su BN, Fong HHS, Van Breemen RB, Pezzuto JM, Kinghorn AD. Minor withanolides from Physalis philadelphica: Structures, quinone reductase induction activities, and liquid chromatography (LC)-MS-MS investigation as artifacts Chemical and Pharmaceutical Bulletin. 51: 530-539. PMID 12736452  1
2003 Li W, Sun Y, Liang W, Fitzloff JF, van Breemen RB. Identification of caffeic acid derivatives in Actea racemosa (Cimicifuga racemosa, black cohosh) by liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 17: 978-82. PMID 12717772 DOI: 10.1002/rcm.1008  1
2003 Su BN, Park EJ, Nikolic D, Santarsiero BD, Mesecar AD, Vigo JS, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity. The Journal of Organic Chemistry. 68: 2350-61. PMID 12636402 DOI: 10.1021/jo020542u  1
2003 Fang L, Pajkovic N, Wang Y, Gu C, van Breemen RB. Quantitative analysis of lycopene isomers in human plasma using high-performance liquid chromatography-tandem mass spectrometry. Analytical Chemistry. 75: 812-7. PMID 12622371 DOI: 10.1021/ac026118a  1
2003 Yu C, Shin YG, Kosmeder JW, Pezzuto JM, van Breemen RB. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Communications in Mass Spectrometry : Rcm. 17: 307-13. PMID 12569440 DOI: 10.1002/rcm.918  1
2003 Li W, Sun Y, Joseph J, Fitzloff JF, Fong HH, van Breemen RB. p-Hydroxybenzoic acid alkyl esters in Andrographis paniculata herbs, commercial extracts, and formulated products. Journal of Agricultural and Food Chemistry. 51: 524-9. PMID 12517121 DOI: 10.1021/jf0258712  1
2003 Van Lieshout M, West CE, Van Breemen RB. Isotopic tracer techniques for studying the bioavailability and bioefficacy of dietary carotenoids, particularly β-carotene, in humans: A review American Journal of Clinical Nutrition. 77: 12-28. PMID 12499318  1
2003 Van Breemen RB. Combinatorial Chemistry & High Throughput Screening: Preface Combinatorial Chemistry and High Throughput Screening. 6.  1
2002 Yu C, Shin YG, Chow A, Li Y, Kosmeder JW, Lee YS, Hirschelman WH, Pezzuto JM, Mehta RG, van Breemen RB. Human, rat, and mouse metabolism of resveratrol. Pharmaceutical Research. 19: 1907-14. PMID 12523673 DOI: 10.1023/A:1021414129280  1
2002 Burdette JE, Chen SN, Lu ZZ, Xu H, White BE, Fabricant DS, Liu J, Fong HH, Farnsworth NR, Constantinou AI, Van Breemen RB, Pezzuto JM, Bolton JL. Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles. Journal of Agricultural and Food Chemistry. 50: 7022-8. PMID 12428954 DOI: 10.1021/jf020725h  1
2002 Yang Y, Nikolic D, Swanson SM, van Breemen RB. Quantitative determination of N7-methyldeoxyguanosine and O6-methyldeoxyguanosine in DNA by LC-UV-MS-MS. Analytical Chemistry. 74: 5376-82. PMID 12403596 DOI: 10.1021/ac020235o  1
2002 Johnson BM, Nikolic D, van Breemen RB. Applications of pulsed ultrafiltration-mass spectrometry. Mass Spectrometry Reviews. 21: 76-86. PMID 12373745 DOI: 10.1002/mas.10020  1
2002 Li W, Sun Y, Fitzloff JF, van Breemen RB. Evaluation of commercial ginkgo and echinacea dietary supplements for colchicine using liquid chromatography-tandem mass spectrometry. Chemical Research in Toxicology. 15: 1174-8. PMID 12230411 DOI: 10.1021/tx025559m  1
2002 Prins GS, Chang WY, Wang Y, van Breemen RB. Retinoic acid receptors and retinoids are up-regulated in the developing and adult rat prostate by neonatal estrogen exposure. Endocrinology. 143: 3628-40. PMID 12193579 DOI: 10.1210/en.2002-220184  1
2002 Liu X, Yao J, Pisha E, Yang Y, Hua Y, van Breemen RB, Bolton JL. Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha. Chemical Research in Toxicology. 15: 512-9. PMID 11952337 DOI: 10.1021/tx0101649  1
2002 van Breemen RB, Xu X, Viana MA, Chen L, Stacewicz-Sapuntzakis M, Duncan C, Bowen PE, Sharifi R. Liquid chromatography-mass spectrometry of cis- and all-trans-lycopene in human serum and prostate tissue after dietary supplementation with tomato sauce. Journal of Agricultural and Food Chemistry. 50: 2214-9. PMID 11929273 DOI: 10.1021/jf0110351  0.8
2002 Geun Shin Y, Bolton JL, van Breemen RB. Screening drugs for metabolic stability using pulsed ultrafiltration mass spectrometry. Combinatorial Chemistry & High Throughput Screening. 5: 59-64. PMID 11860340  1
2002 Wang Y, Catana F, Yang Y, Roderick R, van Breemen RB. An LC-MS method for analyzing total resveratrol in grape juice, cranberry juice, and in wine. Journal of Agricultural and Food Chemistry. 50: 431-5. PMID 11804508 DOI: 10.1021/jf010812u  1
2002 Burdette JE, Liu J, Lantvit D, Lim E, Booth N, Bhat KP, Hedayat S, Van Breemen RB, Constantinou AI, Pezzuto JM, Farnsworth NR, Bolton JL. Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized Sprague-Dawley rats. The Journal of Nutrition. 132: 27-30. PMID 11773503  1
2002 Papadantonakis GA, Tranter R, Brezinsky K, Yang Y, Van Breemen RB, LeBreton PR. Low-energy, low-yield photoionization, and production of 8-oxo-2′-deoxyguanosine and guanine from 2′-deoxyguanosine Journal of Physical Chemistry B. 106: 7704-7712. DOI: 10.1021/jp020649l  1
2002 Johnson BM, Van Breemen RB. Rapid analysis of Cimicifuga racemosa (black cohosh) for the formation of electrophilic phase I metabolites: Investigation of corresponding mercapturates in women Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 399-400.  1
2002 Nikolic D, Li Y, Farnsworth NR, Van Breemen RB. Transport and metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus iupulus) by human intestinal Caco-2 cells and hepatocytes Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 487-488.  1
2002 Van Breemen RB, Wang Y, Van Lieshout M, West CE. Experimental design and application of LC-MS-MS and stable isotope labeling for determination of carotenoid bioavailability Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 77-78.  1
2002 Sun Y, Gu C, Nikolic D, Chadwick LR, Farnsworth NR, Van Breemen RB. Screening of Humulus Iupulus (hops) for estrogenic compounds using ultrafiltration LC-MS Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 397-398.  1
2002 Liu G, Yang Y, Ratia KM, Mesecar A, Van Breemen RB. Ultrafiltration LC/MS method to screen retinoids and natural products for binding to human retinoic acid receptor-gamma (hRAR γ) Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 401-402.  1
2002 Pajkovic N, Nikolic D, Tolga U, Manev H, Van Breemen RB. LC-MS-MS quantitation of N-acetylserotonin in neuronal tissues and cell culture media Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 571-572.  1
2002 Liang W, Nikolic D, Li Y, Li W, Farnsworth NR, Van Breemen RB. Identification of human liver cytochrome P450 isoenzymes for the O-demethylation of three isoflavones in Trifolium pratense (red clover) dietary supplements: Formononetin, biochanin A and prunetin Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 473-474.  1
2002 Kouloumbos VN, Tsipi DF, Hiskia AE, Nikolic D, Van Breemen RB. Identification of photocatalytic degradation products of diazinon using GC/MS/MS and LC/MS with quadrupole time-of-flight mass spectrometry Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 665-666.  1
2002 Yu C, Shin YG, Li Y, Kosmeder JW, Pezzuto JM, Van Breemen RB. Characterization of human UDP-glucuronosyltransferases and sulfotransferases responsible for in vivo metabolism of resveratrol by using LC-DAD-MS and LC-UV-MS-MS Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 439-440.  1
2002 Yang Y, Li Y, Nikolic D, Hong M, Swanson SM, Pajkovic N, Van Breemen RB. Quantitative determination of N-methyl-N-nitrosourea-induced in vitro and in vivo DNA methylation by LC-UV-MS-MS Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 423-424.  1
2001 Constantinou AI, Lantvit D, Hawthorne M, Xu X, Van Breemen RB, Pezzuto JM. Chemopreventive effects of soy protein and purified soy isoflavones on DMBA-induced mammary tumors in female Sprague-Dawley rats Nutrition and Cancer. 41: 75-81. PMID 12094632  1
2001 Shin YG, van Breemen RB. Analysis and screening of combinatorial libraries using mass spectrometry Biopharmaceutics and Drug Disposition. 22: 353-372. PMID 11835254 DOI: 10.1002/bdd.278  1
2001 Garbis SD, Melse-Boonstra A, West CE, van Breemen RB. Determination of folates in human plasma using hydrophilic interaction chromatography-tandem mass spectrometry. Analytical Chemistry. 73: 5358-64. PMID 11816560 DOI: 10.1021/ac010741y  1
2001 Zhang F, Swanson SM, van Breemen RB, Liu X, Yang Y, Gu C, Bolton JL. Equine estrogen metabolite 4-hydroxyequilenin induces DNA damage in the rat mammary tissues: formation of single-strand breaks, apurinic sites, stable adducts, and oxidized bases. Chemical Research in Toxicology. 14: 1654-9. PMID 11743748 DOI: 10.1021/tx010158c  1
2001 Yao D, Zhang F, Yu L, Yang Y, van Breemen RB, Bolton JL. Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones. Chemical Research in Toxicology. 14: 1643-53. PMID 11743747 DOI: 10.1021/tx010137i  1
2001 Johnson BM, Bolton JL, Van Breemen RB. Screening botanical extracts for quinoid metabolites Chemical Research in Toxicology. 14: 1546-1551. PMID 11712913 DOI: 10.1021/tx010106n  1
2001 Wang Y, Chang WY, Prins GS, Van Breemen RB. Simultaneous determination of all-trans, 9-cis, 13-cis retinoic acid and retinol in rat prostate using liquid chromatography-mass spectrometry Journal of Mass Spectrometry. 36: 882-888. PMID 11523087 DOI: 10.1002/jms.189  1
2001 Mitchell DJ, Nikolic D, Jang MH, van Breemen RB, Hille R, Silverman RB. Inactivation of C30A trimethylamine dehydrogenase by N-cyclopropyl-alpha-methylbenzylamine, 1-phenylcyclopropylamine, and phenylhydrazine. Biochemistry. 40: 8523-30. PMID 11456490 DOI: 10.1021/bi0105126  1
2001 Mitchell DJ, Nikolic D, van Breemen RB, Silverman RB. Inactivation of monoamine oxidase B by 1-phenylcyclopropylamine: mass spectral evidence for the flavin adduct. Bioorganic & Medicinal Chemistry Letters. 11: 1757-60. PMID 11425554 DOI: 10.1016/S0960-894X(01)00302-X  1
2001 Zhang F, Yao D, Hua Y, van Breemen RB, Bolton JL. Synthesis and reactivity of the catechol metabolites from the equine estrogen, 8,9-dehydroestrone. Chemical Research in Toxicology. 14: 754-63. PMID 11409947  1
2001 Liu J, Burdette JE, Xu H, Gu C, van Breemen RB, Bhat KP, Booth N, Constantinou AI, Pezzuto JM, Fong HH, Farnsworth NR, Bolton JL. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. Journal of Agricultural and Food Chemistry. 49: 2472-9. PMID 11368622 DOI: 10.1021/jf0014157  1
2001 Park EJ, Lee D, Shin YG, Lantvit DD, van Breemen RB, Kinghorn AD, Pezzuto JM. Analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors using liquid chromatography-electrospray mass spectrometry. Journal of Chromatography. B, Biomedical Sciences and Applications. 754: 327-32. PMID 11339276 DOI: 10.1016/S0378-4347(00)00620-4  0.4
2001 Mitchell DJ, Nikolic D, Rivera E, Sablin SO, Choi S, van Breemen RB, Singer TP, Silverman RB. Spectrometric evidence for the flavin-1-phenylcyclopropylamine inactivator adduct with monoamine oxidase N. Biochemistry. 40: 5447-56. PMID 11331009 DOI: 10.1021/bi010388q  1
2001 Nikolic D, van Breemen RB. DNA oxidation induced by cyclooxygenase-2. Chemical Research in Toxicology. 14: 351-4. PMID 11304122 DOI: 10.1021/tx010004x  1
2001 Chang M, Shin YG, van Breemen RB, Blond SY, Bolton JL. Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin. Biochemistry. 40: 4811-20. PMID 11294649 DOI: 10.1021/bi002513o  1
2001 Hua Y, Wainhaus SB, Yang Y, Shen L, Xiong Y, Xu X, Zhang F, Bolton JL, van Breemen RB. Comparison of negative and positive ion electrospray tandem mass spectrometry for the liquid chromatography tandem mass spectrometry analysis of oxidized deoxynucleosides. Journal of the American Society For Mass Spectrometry. 12: 80-7. PMID 11142363 DOI: 10.1016/S1044-0305(00)00191-4  1
2000 Li W, Gu C, Zhang H, Awang DV, Fitzloff JF, Fong HH, van Breemen RB. Use of high-performance liquid chromatography-tandem mass spectrometry to distinguish Panax ginseng C. A. Meyer (Asian ginseng) and Panax quinquefolius L. (North American ginseng). Analytical Chemistry. 72: 5417-22. PMID 11080895 DOI: 10.1021/ac000650l  0.52
2000 Wang Y, Xu X, van Lieshout M, West CE, Lugtenburg J, Verhoeven MA, Creemers AF, Muhilal, van Breemen RB. A liquid chromatography-mass spectrometry method for the quantification of bioavailability and bioconversion of beta-carotene to retinol in humans. Analytical Chemistry. 72: 4999-5003. PMID 11055721 DOI: 10.1021/ac000454e  1
2000 Henry LK, Puspitasari-Nienaber NL, Jarén-Galán M, van Breemen RB, Catignani GL, Schwartz SJ. Effects of ozone and oxygen on the degradation of carotenoids in an aqueous model system. Journal of Agricultural and Food Chemistry. 48: 5008-13. PMID 11052770 DOI: 10.1021/jf000503o  1
2000 Nikolic D, Habibi-Goudarzi S, Corley DG, Gafner S, Pezzuto JM, van Breemen RB. Evaluation of cyclooxygenase-2 inhibitors using pulsed ultrafiltration mass spectrometry. Analytical Chemistry. 72: 3853-9. PMID 10959973 DOI: 10.1021/ac0000980  1
2000 Chen Y, Liu X, Pisha E, Constantinou AI, Hua Y, Shen L, van Breemen RB, Elguindi EC, Blond SY, Zhang F, Bolton JL. A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines. Chemical Research in Toxicology. 13: 342-50. PMID 10813650 DOI: 10.1021/tx990186j  1
2000 Zhang F, Fan PW, Liu X, Shen L, van Breemen RB, Bolton JL. Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-dihydroxytamoxifen-o-quinone. Chemical Research in Toxicology. 13: 53-62. PMID 10649967 DOI: 10.1021/tx990145n  1
2000 Hamm ML, Nikolic D, Van Breemen RB, Piccirilli JA. Unconventional origin of metal ion rescue in the hammerhead ribozyme reaction: Mn2+-assisted redox conversion of 2′-mercaptocytidine to cytidine Journal of the American Chemical Society. 122: 12069-12078. DOI: 10.1021/ja000379p  1
2000 Van Breemen RB. Preface Combinatorial Chemistry and High Throughput Screening. 3.  1
1999 Gu C, Nikolic D, Lai J, Xu X, Van Breemen RB. Assays of ligand-human serum albumin binding using pulsed ultrafiltration and liquid chromatography-mass spectrometry Combinatorial Chemistry and High Throughput Screening. 2: 353-359. PMID 10644860  1
1999 Xu X, Wang Y, Constantinou AI, Stacewicz-Sapuntzakis M, Bowen PE, Van Breemen RB. Solubilization and stabilization of carotenoids using micelles: Delivery of lycopene to cells in culture Lipids. 34: 1031-1036. PMID 10580330 DOI: 10.1007/s11745-999-0454-9  1
1999 Chung HS, Chang LC, Lee SK, Shamon LA, Van Breemen RB, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Flavonoid constituents of Chorizanthe diffusa with potential cancer chemopreventive activity Journal of Agricultural and Food Chemistry. 47: 36-41. PMID 10563845 DOI: 10.1021/jf980784o  1
1999 Nikolic D, Fan PW, Bolton JL, van Breemen RB. Screening for xenobiotic electrophilic metabolites using pulsed ultrafiltration-mass spectrometry. Combinatorial Chemistry & High Throughput Screening. 2: 165-75. PMID 10420970  1
1999 Korecka M, Nikolic D, Van Breemen RB, Shaw LM. The apparent inhibition of inosine monophosphate dehydrogenase by mycophenolic acid glucuronide is attributable to the presence of trace quantities of mycophenolic acid Clinical Chemistry. 45: 1047-1050. PMID 10388481  1
1999 Zhang F, Chen Y, Pisha E, Shen L, Xiong Y, van Breemen RB, Bolton JL. The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone. Chemical Research in Toxicology. 12: 204-13. PMID 10027800 DOI: 10.1021/tx980217v  1
1999 Fu M, Nikolic D, Van Breemen RB, Silverman RB. Mechanism of inactivation of γ-aminobutyric acid aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid Journal of the American Chemical Society. 121: 7751-7759. DOI: 10.1021/ja9915551  1
1999 Fast W, Nikolic D, Van Breemen RB, Silverman RB. Mechanistic studies of the inactivation of inducible nitric oxide synthase by N5-(1-iminoethyl)-L-ornithine (L-NIO) Journal of the American Chemical Society. 121: 903-916. DOI: 10.1021/ja982318l  1
1998 Nikolic D, Van Breemen RB. Screening for inhibitors of dihydrofolate reductase using pulsed ultrafiltration mass spectrometry Combinatorial Chemistry and High Throughput Screening. 1: 47-55. PMID 10499129  1
1998 Chen Y, Shen L, Zhang F, Lau SS, van Breemen RB, Nikolic D, Bolton JL. The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro. Chemical Research in Toxicology. 11: 1105-11. PMID 9760286 DOI: 10.1021/tx980083l  1
1998 Chang M, Zhang F, Shen L, Pauss N, Alam I, van Breemen RB, Blond SY, Bolton JL. Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens. Chemical Research in Toxicology. 11: 758-65. PMID 9671538 DOI: 10.1021/tx9702190  1
1998 Shen L, Qiu S, Chen Y, Zhang F, van Breemen RB, Nikolic D, Bolton JL. Alkylation of 2'-deoxynucleosides and DNA by the Premarin metabolite 4-hydroxyequilenin semiquinone radical. Chemical Research in Toxicology. 11: 94-101. PMID 9511900 DOI: 10.1021/tx970181r  1
1998 van Breemen RB, Nikolic D, Xu X, Xiong Y, van Lieshout M, West CE, Schilling AB. Development of a method for quantitation of retinol and retinyl palmitate in human serum using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry. Journal of Chromatography. A. 794: 245-51. PMID 9491562 DOI: 10.1016/S0021-9673(97)01138-2  1
1998 Van Breemen RB, Nikolic D, Bolton JL. Metabolic screening using on-line ultrafiltration mass spectrometry Drug Metabolism and Disposition. 26: 85-90. PMID 9456292  1
1998 Van Breemen RB, Tan Y, Lai J, Huang CR, Zhao X. Immobilized thymine chromatography-mass spectrometry of oligonucleotides Journal of Chromatography A. 806: 67-76. DOI: 10.1016/S0021-9673(98)00153-8  1
1997 Zhao YZ, van Breemen RB, Nikolic D, Huang CR, Woodbury CP, Schilling A, Venton DL. Screening solution-phase combinatorial libraries using pulsed ultrafiltration/electrospray mass spectrometry. Journal of Medicinal Chemistry. 40: 4006-12. PMID 9406591 DOI: 10.1021/jm960729b  1
1997 Bolton JL, Pisha E, Shen L, Krol ES, Iverson SL, Huang Z, Van Breemen RB, Pezzuto JM. The reactivity of o-quinones which do not isomerize to quinone methides correlates with alkylcatechol-induced toxicity in human melanoma cells Chemico-Biological Interactions. 106: 133-148. PMID 9366899 DOI: 10.1016/S0009-2797(97)00066-5  1
1997 Van Breemen RB, Huang CR, Nikolic D, Woodbury CP, Zhao YZ, Venton DL. Pulsed ultrafiltration mass spectrometry: A new method for screening combinatorial libraries Analytical Chemistry. 69: 2159-2164. PMID 9183179 DOI: 10.1021/ac970132j  1
1997 Shen L, Pisha E, Huang Z, Pezzuto JM, Krol E, Alam Z, Van Breemen RB, Bolton JL. Bioreductive activation of catechol estrogen-ortho-quinones: Aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity Carcinogenesis. 18: 1093-1101. PMID 9163701 DOI: 10.1093/carcin/18.5.1093  1
1997 Shen L, Qiu S, Van Breemen RB, Zhang F, Chen Y, Bolton JL. Reaction of the premarin metabolite 4-hydroxyequilenin semiquinone radical with 2'-deoxyguanosine: Formation of unusual cyclic adducts Journal of the American Chemical Society. 119: 11126-11127. DOI: 10.1021/ja971396q  1
1997 Van Breemen RB. Liquid chromatography/mass spectrometry of carotenoids Pure and Applied Chemistry. 69: 2061-2066.  1
1996 Van Breemen RB, Huang CR. High-performance liquid chromatography-electrospray mass spectrometry of retinoids Faseb Journal. 10: 1098-1101. PMID 8801173  1
1996 Van Breemen RB, Huang CR, Tan Y, Sander LC, Schilling AB. Liquid chromatography/mass spectrometry of carotenoids using atmospheric pressure chemical ionization Journal of Mass Spectrometry. 31: 975-981. DOI: 10.1002/(SICI)1096-9888(199609)31:9<975::AID-JMS380>3.0.CO;2-S  1
1996 Van Breemen RB. Innovations in carotenoid analysis using LC/MS Analytical Chemistry. 68.  1
1995 Spanos GA, Schwartz SJ, van Breemen RB, Huang CH. High-performance liquid chromatography with light-scattering detection and desorption chemical-ionization tandem mass spectrometry of milk fat triacylglycerols Lipids. 30: 85-90. PMID 7760693 DOI: 10.1007/BF02537046  1
1995 Van Breemen RB, Huang CR, Lu ZZ, Rimando A, Fong HHS, Fitzloff JF. Electrospray liquid chromatography/mass spectrometry of ginsenosides Analytical Chemistry. 67: 3985-3989. DOI: 10.1021/ac00117a026  1
1995 Van Breemen RB. Electrospray liquid chromatography-mass spectrometry of carotenoids Analytical Chemistry. 67: 2004-2009.  1
1995 Van Breemen RB, Schmitz HH, Schwartz SJ. Fast atom bombardment tandem mass spectrometry of carotenoids Journal of Agricultural and Food Chemistry. 43: 384-389.  1
1995 Van Breemen RB, Jiang O, Tidwell RR, Hall JE, Brewer TG. Fast atom bombardment tandem mass spectrometry of the anti-parasitic agent pentamidine and its oxygenated metabolites Journal of Mass Spectrometry. 30: 549-556.  1
1993 Blackburn RK, Van Breemen RB. Application of an immobilized digestive enzyme assay to measure chemical and enzymatic hydrolysis of the cyclic peptide antibiotic lysobactin Drug Metabolism and Disposition. 21: 573-579. PMID 8104115  1
1993 Saljoughian M, Williams PG, Morimoto H, Goodlett DR, Van Breemen RB. Tritiated diimide: A regio- and stereo-selective tritium-labelling reagent Journal of the Chemical Society, Chemical Communications. 414-416. DOI: 10.1039/C39930000414  1
1993 Van Breemen RB, Tsou Y, Connolly G. Oxidation of dicyclopentadiene in surface water Biological Mass Spectrometry. 22: 579-584.  1
1993 Van Breemen RB, Schmitz HH, Schwartz SJ. Continuous-flow fast atom bombardment liquid chromatography/mass spectrometry of carotenoids Analytical Chemistry. 65: 965-969.  1
1992 Van Breemen RB, Davis RG. Rates of peptide proteolysis measured using liquid chromatography and continuous-flow fast atom bombardment mass spectrometry Analytical Chemistry. 64: 2233-2237. PMID 1449212  1
1992 Bumgardner CL, Huang CH, Van Breemen RB. Characterization of oligomers of 3,3,3-trifluoro-1-phenylpropyne and 1-phenylpropyne by mass spectrometry Journal of Fluorine Chemistry. 56: 175-187. DOI: 10.1016/S0022-1139(00)81100-8  1
1992 Schmitz HH, Van Breemen RB, Schwartz SJ. Fast-atom bombardment and continuous-flow fast-atom bombardment mass spectrometry in carotenoid analysis Methods in Enzymology. 213: 322-336. DOI: 10.1016/0076-6879(92)13134-J  1
1991 van Breemen RB, Martin LB, Le JC. Continuous-flow fast atom bombardment mass spectrometry of oligonucleotides. Journal of the American Society For Mass Spectrometry. 2: 157-63. PMID 24242175 DOI: 10.1016/1044-0305(91)80009-V  1
1991 Martin LB, Schreiner AF, van Breemen RB. Characterization of cisplatin adducts of oligonucleotides by fast atom bombardment mass spectrometry. Analytical Biochemistry. 193: 6-15. PMID 2042743 DOI: 10.1016/0003-2697(91)90035-R  1
1991 Van Breemen RB, Bartlett MG, Tsou YH, Culver C, Swaisgood H, Unger SE. Degradation of peptide drugs by immobilized digestive proteases. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 19: 683-90. PMID 1680637  1
1991 van Breemen RB, Canjura FL, Schwartz SJ. High-performance liquid chromatography-continuous-flow fast atom bombardment mass spectrometry of chlorophyll derivatives Journal of Chromatography A. 542: 373-383. DOI: 10.1016/S0021-9673(01)88776-8  1
1991 Freeman HS, Hao Z, Sokotowska-Gajda J, van Breemen RB, Le JC. Matrix selection for the analysis of hydrophilic dyes by fast atom bombardment mass spectrometry Dyes and Pigments. 16: 317-327. DOI: 10.1016/0143-7208(91)85021-Y  1
1991 Van Breemen RB, Huang CH, Bumgardner CL. Continuous-flow fast atom bombardment and field desorption mass spectrometry of oligomers of 3,3,3-trifluoro-1-phenylpropyne Analytical Chemistry. 63: 2577-2580.  1
1990 Goodlett DR, Armstrong FB, Creech RJ, van Breemen RB. Formylated peptides from cyanogen bromide digests identified by fast atom bombardment mass spectrometry Analytical Biochemistry. 186: 116-120. PMID 2356963 DOI: 10.1016/0003-2697(90)90583-U  1
1990 van Breemen RB, Wheeler JJ, Boss WF. Identification of carrot inositol phospholipids by fats atom bombardment mass spectrometry Lipids. 25: 328-334. DOI: 10.1007/BF02544342  1
1989 van Breemen RB, Le JC. Enhanced sensitivity of peptide analysis by fast-atom bombardment mass spectrometry using nitrocellulose as a substrate Rapid Communications in Mass Spectrometry : Rcm. 3: 20-24. PMID 2485176  1
1988 Van Breemen RB, Stogniew M, Fenselau C. Characterization of acyl-linked glucuronides by electron impact and fast atom bombardment mass spectrometry Biomedical and Environmental Mass Spectrometry. 17: 97-103. PMID 3191255 DOI: 10.1002/bms.1200170205  1
1988 Van Breemen RB. Comparison of electron impact, desorption chemical ionization, field desorption, and fast atom bombardment mass spectra of nine monosubstituted group VI metal carbonyls Analytical® Chemistry. 60: 1314-1318.  1
1987 van Breemen RB, Fenselau CC, Cotter RJ, Curtis AJ, Connolly G. Derivatives of dicyclopentadiene in ground water. Biomedical & Environmental Mass Spectrometry. 14: 97-102. PMID 2953399 DOI: 10.1002/bms.1200140302  1
1986 Van Breemen RB, Fenselau C, Mogilevsky W, Odell GB. Reaction of bilirubin glucuronides with serum albumin Journal of Chromatography B: Biomedical Sciences and Applications. 383: 387-392. PMID 3558567 DOI: 10.1016/S0378-4347(00)83484-2  1
1986 van Breemen RB, Fenselau CC, Dulik DM. Activated phase II metabolites: comparison of alkylation by 1-O-acyl glucuronides and acyl sulfates Advances in Experimental Medicine and Biology. 197: 423-429. PMID 3094339 DOI: 10.1007/978-1-4684-5134-4_41  1
1986 Van Breemen RB, Fenselau CC. Reaction of 1-O-acyl glucuronides with 4-(p-nitrobenzyl)pyridine Drug Metabolism and Disposition. 14: 197-201. PMID 2870894  1
1985 Van Breemen RB, Fenselau C. Acylation of albumin by 1-O-acyl glucuronides Drug Metabolism and Disposition. 13: 318-320. PMID 2861990  1
1984 Van Breemen RB, Tabet JC, Cotter RJ. Characterization of oxygen-linked glucuronides by laser desorption mass spectrometry Biomedical Mass Spectrometry. 11: 278-283. PMID 6743767 DOI: 10.1002/bms.1200110606  1
1984 Van Breemen RB, Fenselau CC. Electrophilic reactions of acyl-linked glucuronides Federation Proceedings. 43.  1
1983 Van Breemen RB, Snow M, Cotter RJ. Time-resolved laser desorption mass spectrometry. I. Desorption of preformed ions International Journal of Mass Spectrometry and Ion Physics. 49: 35-50. DOI: 10.1016/0020-7381(83)85074-8  1
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