Richard B. Van Breemen, Ph.D. - Publications

Affiliations: 
1986-1993 Chemistry North Carolina State University, Raleigh, NC 
 1994-2017 Medicinal Chemistry and Pharmacognosy University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
 2018- Pharmaceutical Sciences and Linus Pauling Institute Oregon State University, Corvallis, OR 
Area:
Pharmaceutical Chemistry, Analytical Chemistry, Biochemistry
Website:
https://blogs.oregonstate.edu/vanbreemen/

229 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Rebiai R, Rue E, Zaldua S, Nguyen D, Scesa G, Jastrzebski M, Foster R, Wang B, Jiang X, Tai L, Brady ST, van Breemen R, Givogri MI, Sands MS, Bongarzone ER. CRISPR-Cas9 Knock-In of T513M and G41S Mutations in the Murine β-Galactosyl-Ceramidase Gene Re-capitulates Early-Onset and Adult-Onset Forms of Krabbe Disease. Frontiers in Molecular Neuroscience. 15: 896314. PMID 35620447 DOI: 10.3389/fnmol.2022.896314  0.766
2022 Reiter CR, Rebiai R, Kwak A, Marshall J, Wozniak D, Scesa G, Nguyen D, Rue E, Pathmasiri C, Pijewski R, van Breemen R, Cologna S, Crocker SJ, Givogri MI, Bongarzone ER. The Pathogenic Sphingolipid Psychosine is Secreted in Extracellular Vesicles in the Brain of a Mouse Model of Krabbe Disease. Asn Neuro. 14: 17590914221087817. PMID 35300522 DOI: 10.1177/17590914221087817  0.766
2021 Burton TCJ, Lankin DC, Nikolic D, Guo B, Ju J, Dietz BM, Che CT, Soejarto DD, van Breemen RB. Isolation and elucidation of two isoflavonoids from an American Indian plant, Pursh, using Magnetic Microbead Affinity Selection Screening (MagMASS) for estrogen receptor alpha ligands. Phytochemistry Letters. 45: 110-116. PMID 35465454 DOI: 10.1016/j.phytol.2021.07.018  0.542
2021 Muchiri RN, van Breemen RB. Drug discovery from natural products using affinity selection-mass spectrometry. Drug Discovery Today. Technologies. 40: 59-63. PMID 34916024 DOI: 10.1016/j.ddtec.2021.10.005  0.305
2021 Molina J, Nikolic D, Jeevarathanam JR, Abzalimov R, Park EJ, Pedales R, Mojica EE, Tandang D, McLaughlin W, Wallick K, Adams J, Novy A, Pell SK, van Breemen RB, Pezzuto JM. Living with a giant, flowering parasite: metabolic differences between Tetrastigma loheri Gagnep. (Vitaceae) shoots uninfected and infected with Rafflesia (Rafflesiaceae) and potential applications for propagation. Planta. 255: 4. PMID 34841446 DOI: 10.1007/s00425-021-03787-x  0.477
2021 van Breemen RB, Hafner JW, Nosal DG, Feinstein DL, Rubinstein I. Unmet clinical laboratory need in patients hospitalized for acute poisoning from long-acting anticoagulant rodenticides. Toxicology Communications. 5: 93-96. PMID 34458660 DOI: 10.1080/24734306.2021.1925444  0.796
2021 Nosal DG, van Breemen RB, Haffner JW, Rubinstein I, Feinstein DL. Brodifacoum pharmacokinetics in acute human poisoning: implications for estimating duration of vitamin K therapy. Toxicology Communications. 5: 69-72. PMID 33768191 DOI: 10.1080/24734306.2021.1887637  0.773
2021 Heller GJ, Marshall MS, Issa Y, Marshall JN, Nguyen D, Rue E, Pathmasiri KC, Domowicz MS, van Breemen RB, Tai LM, Cologna SM, Crocker SJ, Givogri MI, Sands MS, Bongarzone ER. Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33508430 DOI: 10.1016/j.ymthe.2021.01.026  0.767
2021 Nosal DG, Feinstein DL, van Breemen RB. Chiral liquid chromatography-tandem mass spectrometry analysis of superwarfarin rodenticide stereoisomers - Bromadiolone, difenacoum and brodifacoum - In human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1165: 122529. PMID 33486217 DOI: 10.1016/j.jchromb.2021.122529  0.811
2020 Nosal DG, Feinstein DL, Chen L, van Breemen RB. Separation and Quantification of Superwarfarin Rodenticide Diastereomers-Bromadiolone, Difenacoum, Flocoumafen, Brodifacoum, and Difethialone-in Human Plasma. Journal of Aoac International. 103: 770-778. PMID 33241367 DOI: 10.1093/Jaoacint/Qsaa007  0.776
2020 Chen L, Choi J, Leonard SW, Banuvar S, Barengolts E, Viana M, Chen SN, Pauli GF, Bolton JL, van Breemen RB. No Clinically Relevant Pharmacokinetic Interactions of a Red Clover Dietary Supplement with Cytochrome P450 Enzymes in Women. Journal of Agricultural and Food Chemistry. PMID 33197178 DOI: 10.1021/acs.jafc.0c05856  0.717
2020 van Breemen RB, Chen L, Tonsing-Carter A, Banuvar S, Barengolts E, Viana M, Chen SN, Pauli GF, Bolton JB. Pharmacokinetic interactions of a hop dietary supplement with drug metabolism in peri-menopausal and post-menopausal women. Journal of Agricultural and Food Chemistry. PMID 32285669 DOI: 10.1021/Acs.Jafc.0C01077  0.74
2020 Yu Y, Pauli GF, Huang L, Gan LS, van Breemen RB, Li D, McAlpine JB, Lankin DC, Chen SN. Classification of Flavonoid Metabolomes via Data Mining and Quantification of Hydroxyl NMR Signals. Analytical Chemistry. PMID 32108467 DOI: 10.1021/acs.analchem.9b05084  0.681
2020 van Breemen RB, Hathout Y, Fabris D. Catherine Fenselau: A distinguished career dedicated to biomedical mass spectrometry. Journal of Mass Spectrometry : Jms. 55: e4500. PMID 32073193 DOI: 10.1002/jms.4500  0.563
2019 Chen L, van Breemen RB. Validation of a sensitive UHPLC-MS/MS method for cytochrome P450 probe substrates caffeine, tolbutamide, dextromethorphan, and alprazolam in human serum reveals drug contamination of serum used for research. Journal of Pharmaceutical and Biomedical Analysis. 112983. PMID 31744669 DOI: 10.1016/j.jpba.2019.112983  0.75
2019 Feinstein DL, Nosal DG, Ramanathan S, Zhou J, Chen L, Hershow RC, van Breemen RB, Wright E, Hafner JW, Rubinstein I. Effects of vitamin K1 treatment on plasma concentrations of long-acting anticoagulant rodenticide enantiomers following inhalation of contaminated synthetic cannabinoids. Clinical Toxicology (Philadelphia, Pa.). 1-9. PMID 31736367 DOI: 10.1080/15563650.2019.1687903  0.774
2019 Fang J, Nikolic D, Lankin DC, Simmler C, Chen SN, Ramos Alvarenga RF, Liu Y, Pauli GF, van Breemen RB. Formation of (2R)- and (2S)-8-Prenylnaringenin Glucuronides by Human UDP-Glucuronosyltransferases. Journal of Agricultural and Food Chemistry. PMID 31554401 DOI: 10.1021/acs.jafc.9b04657  0.538
2019 Rasin A, Devgun JM, Nosal DG, Meehan TJ, van Breemen RB, Thompson TM. Coagulopathy After Synthetic Cannabinoid Use: A Case Report. Annals of Internal Medicine. PMID 31450243 DOI: 10.7326/L19-0321  0.752
2019 Bolton JL, Dunlap TL, Hajirahimkhan A, Mbachu O, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM. Correction to The Multiple Biological Targets of Hops and Bioactive Compounds. Chemical Research in Toxicology. PMID 31392882 DOI: 10.1021/Acs.Chemrestox.9B00300  0.501
2019 Rue EA, Glinski JA, Glinski VB, van Breemen RB. Ion Mobility-Mass Spectrometry for the Separation and Analysis of Procyanidins. Journal of Mass Spectrometry : Jms. PMID 31144405 DOI: 10.1002/jms.4377  0.801
2019 Rubinstein I, van Breemen R, Nosal DG, Weinberg G, Hershow RC, Feinstein DL. Should Cytochrome P450 Inducers be Used to Accelerate Clearance of Brodifacoum from Poisoned Patients? Drugs in R&D. PMID 30689138 DOI: 10.1007/S40268-019-0261-4  0.78
2019 Bolton JL, Dunlap TL, Hajirahimkhan DA, Mbachu OC, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM. The Multiple Biological Targets of Hops and Bioactive Compounds. Chemical Research in Toxicology. PMID 30608650 DOI: 10.1021/Acs.Chemrestox.8B00345  0.544
2018 Wang S, Dunlap TL, Huang L, Liu Y, Simmler C, Lantvit DD, Crosby J, Howell CE, Dong H, Chen SN, Pauli GF, van Breemen RB, Dietz BM, Bolton JL. Evidence for Chemopreventive and resilience activity of licorice: Glycyrrhiza glabra and G. inflata extracts modulate estrogen metabolism in ACI rats. Cancer Prevention Research (Philadelphia, Pa.). PMID 30287522 DOI: 10.1158/1940-6207.Capr-18-0178  0.69
2018 Rush MD, Rue EA, Wong AM, Kowalski P, Glinski JA, van Breemen RB. Rapid Determination of Procyanidins Using MALDI-ToF/ToF Mass Spectrometry. Journal of Agricultural and Food Chemistry. PMID 30286291 DOI: 10.1021/acs.jafc.8b04258  0.79
2018 Abdelkarim H, Marshall MS, Scesa G, Smith RA, Rue E, Marshall J, Elackattu V, Stoskute M, Issa Y, Santos M, Nguyen D, Hauck Z, van Breemen R, Celej MS, Gaponenko V, et al. α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies. Scientific Reports. 8: 12462. PMID 30127535 DOI: 10.1038/S41598-018-30808-9  0.752
2018 Rue EA, Rush MD, van Breemen RB. Procyanidins: a comprehensive review encompassing structure elucidation via mass spectrometry. Phytochemistry Reviews : Proceedings of the Phytochemical Society of Europe. 17: 1-16. PMID 29651231 DOI: 10.1007/s11101-017-9507-3  0.804
2018 Hajirahimkhan A, Mbachu O, Simmler C, Ellis SG, Dong H, Nikolic D, Lankin DC, van Breemen RB, Chen SN, Pauli GF, Dietz BM, Bolton JL. Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication. Journal of Natural Products. PMID 29641206 DOI: 10.1021/Acs.Jnatprod.7B01070  0.525
2018 Marshall MS, Jakubauskas B, Bogue W, Stoskute M, Hauck Z, Rue E, Nichols M, DiAntonio LL, van Breemen RB, Kordower JH, Saavedra-Matiz CA, Bongarzone ER. Analysis of age-related changes in psychosine metabolism in the human brain. Plos One. 13: e0193438. PMID 29481565 DOI: 10.1371/Journal.Pone.0193438  0.759
2018 Marshall MS, Issa Y, Jakubauskas B, Stoskute M, Elackattu V, Marshall JN, Bogue W, Nguyen D, Hauck Z, Rue E, Karumuthil-Melethil S, Zaric V, Bosland M, van Breemen RB, Givogri MI, et al. Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29433937 DOI: 10.1016/J.Ymthe.2018.01.009  0.76
2017 Huang L, Nikolic D, van Breemen RB. Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry. PMID 29127460 DOI: 10.1007/s00216-017-0642-x  0.777
2017 Keiler AM, Macejova D, Dietz BM, Bolton JL, Pauli GF, Chen SN, van Breemen RB, Nikolic D, Goerl F, Muders MH, Zierau O, Vollmer G. Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28964928 DOI: 10.1016/J.Jsbmb.2017.09.020  0.509
2017 Kalinin S, Marangoni N, Kowal K, Dey A, Lis K, Brodsky S, van Breemen R, Hauck Z, Ripper R, Rubinstein I, Weinberg G, Feinstein DL. The Long-Lasting Rodenticide Brodifacoum Induces Neuropathology in Adult Male Rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 159: 224-237. PMID 28903499 DOI: 10.1093/Toxsci/Kfx134  0.773
2017 Keiler AM, Helle J, Bader MI, Ehrhardt T, Nestler K, Kretzschmar G, Bernhardt R, Vollmer G, Nikolić D, Bolton JL, Pauli GF, Chen SN, Dietz BM, van Breemen RB, Zierau O. A standardized Humulus lupulus (L.) ethanol extract partially prevents ovariectomy-induced bone loss in the rat without induction of adverse effects in the uterus. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 34: 50-58. PMID 28899509 DOI: 10.1016/J.Phymed.2017.08.001  0.484
2017 Dietz BM, Chen SN, Alvarenga RFR, Dong H, Nikolić D, Biendl M, van Breemen RB, Bolton JL, Pauli GF. DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women's Health. Journal of Natural Products. PMID 28812892 DOI: 10.1021/Acs.Jnatprod.7B00284  0.538
2017 Li G, Simmler C, Chen L, Nikolic D, Chen SN, Pauli GF, van Breemen RB. Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28774812 DOI: 10.1016/j.ejps.2017.07.034  0.791
2017 Simmler C, Lankin DC, Nikolić D, van Breemen RB, Pauli GF. Isolation and structural characterization of dihydrobenzofuran congeners of licochalcone A. Fitoterapia. PMID 28647482 DOI: 10.1016/j.fitote.2017.06.017  0.502
2017 Nikolić D, Macias C, Lankin DC, van Breemen RB. Collision-induced dissociation of phenethylamides: role of ion-neutral complex. Rapid Communications in Mass Spectrometry : Rcm. PMID 28558170 DOI: 10.1002/rcm.7915  0.511
2017 D'Auria L, Reiter C, Ward E, Moyano AL, Marshall MS, Nguyen D, Scesa G, Hauck Z, van Breemen R, Givogri MI, Bongarzone ER. Psychosine enhances the shedding of membrane microvesicles: Implications in demyelination in Krabbe's disease. Plos One. 12: e0178103. PMID 28531236 DOI: 10.1371/Journal.Pone.0178103  0.762
2016 Simmler C, Chen SN, Anderson J, Lankin DC, Phansalkar R, Krause E, Dietz B, Bolton JL, Nikolic D, van Breemen RB, Pauli GF. Botanical Integrity: Part 2: Traditional and Modern Analytical Approaches. Herbalgram. 109: 60-64. PMID 30287984  0.493
2016 Rush MD, Walker EM, Prehna G, Burton T, van Breemen RB. Development of a Magnetic Microbead Affinity Selection Screen (MagMASS) Using Mass Spectrometry for Ligands to the Retinoid X Receptor-α. Journal of the American Society For Mass Spectrometry. PMID 27966173 DOI: 10.1007/s13361-016-1564-0  0.787
2016 Rush MD, van Breemen RB. Role of ammonium in the ionization of phosphatidylcholines during electrospray mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. PMID 27862466 DOI: 10.1002/rcm.7788  0.801
2016 Rush MD, Walker EM, Burton T, van Breemen RB. Magnetic Microbead Affinity Selection Screening (MagMASS) of Botanical Extracts for Inhibitors of 15-Lipoxygenase. Journal of Natural Products. PMID 27802026 DOI: 10.1021/acs.jnatprod.6b00693  0.778
2016 Li G, Nikolic D, van Breemen RB. Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS. Journal of Agricultural and Food Chemistry. PMID 27696846 DOI: 10.1021/acs.jafc.6b02954  0.723
2016 Moyano AL, Li G, Boullerne AI, Feinstein DL, Hartman E, Skias D, Balavanov R, van Breemen RB, Bongarzone ER, Månsson JE, Givogri MI. Sulfatides in extracellular vesicles isolated from plasma of multiple sclerosis patients. Journal of Neuroscience Research. PMID 27557608 DOI: 10.1002/Jnr.23899  0.61
2016 Feinstein DL, Akpa BS, Ayee MA, Boullerne AI, Braun D, Brodsky SV, Gidalevitz D, Hauck Z, Kalinin S, Kowal K, Kuzmenko I, Lis K, Marangoni N, Martynowycz MW, Rubinstein I, ... van Breemen R, et al. The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures. Annals of the New York Academy of Sciences. PMID 27244102 DOI: 10.1111/Nyas.13085  0.769
2016 Vandenberg LN, Gerona RR, Kannan K, Taylor JA, van Breemen RB, Dickenson CA, Liao C, Yuan Y, Newbold RR, Padmanabhan V, Vom Saal FS, Woodruff TJ. Erratum to: A round robin approach to the analysis of bisphenol a (BPA) in human blood samples. Environmental Health : a Global Access Science Source. 15: 43. PMID 26956378 DOI: 10.1186/s12940-016-0126-z  0.387
2016 Kataria Y, Deaton RJ, Enk E, Jin M, Petrauskaite M, Dong L, Goldenberg JR, Cotler SJ, Jensen DM, van Breemen RB, Gann PH. Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer. Bmc Gastroenterology. 16: 30. PMID 26927700 DOI: 10.1186/s12876-016-0432-5  0.599
2016 Hauck ZZ, Feinstein DL, van Breemen RB. LC-MS-MS Analysis of Brodifacoum Isomers in Rat Tissue. Journal of Analytical Toxicology. PMID 26912564 DOI: 10.1093/Jat/Bkw008  0.809
2016 Newsome AG, Li Y, van Breemen RB. Improved quantification of free and ester bound gallic acid in food and beverages by UHPLC-MS/MS. Journal of Agricultural and Food Chemistry. PMID 26804199 DOI: 10.1021/acs.jafc.5b04966  0.808
2016 Imai A, Lankin DC, Nikolić D, Ahn S, van Breemen RB, Farnsworth NR, McAlpine JB, Chen SN, Pauli GF. Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa. Journal of Natural Products. PMID 26760374 DOI: 10.1021/Acs.Jnatprod.5B00927  0.602
2016 Hauck ZZ, Huang K, Li G, van Breemen RB. Determination of bisphenol A-glucuronide in human urine using ultrahigh-pressure liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 30: 400-6. PMID 26754133 DOI: 10.1002/rcm.7450  0.808
2015 Simmler C, Chen SN, Anderson J, Lankin DC, Phansalkar R, Krause E, Dietz B, Bolton JL, Nikolic D, van Breemen RB, Pauli GF. Botanical Integrity: The Importance of the Integration of Chemical, Biological, and Botanical Analyses, and the Role of DNA Barcoding. Herbalgram. 106: 58-60. PMID 30287983  0.506
2015 Nikolić D, Lankin DC, Cisowska T, Chen SN, Pauli GF, van Breemen RB. Nitrogen-Containing Constituents of Black Cohosh: Chemistry, Structure Elucidation, and Biological Activities. Recent Advances in Phytochemistry. 45: 31-75. PMID 27795590 DOI: 10.1007/978-3-319-20397-3_2  0.513
2015 Zhou Q, Chen T, Zhang W, Bozkanat M, Li Y, Xiao L, van Breemen RB, Christman JW, Sznajder JI, Zhou G. Suppression of Von Hippel-Lindau Protein in Fibroblasts Protects Against Bleomycin-induced Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology. PMID 26488390 DOI: 10.1165/Rcmb.2015-0111Oc  0.495
2015 Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen SN, Nikolic D, Pauli GF, van Breemen RB, Dietz BM, Bolton JL. Induction of NAD(P)H:quinone oxidoreductase 1 (NQO1) by Glycyrrhiza species used for women's health: differential effects of the Michael acceptors isoliquiritigenin and licochalcone A. Chemical Research in Toxicology. PMID 26473469 DOI: 10.1021/Acs.Chemrestox.5B00310  0.669
2015 Li G, Huang K, Nikolic D, van Breemen RB. High-throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26285764 DOI: 10.1124/dmd.115.065987  0.722
2015 Parvinian A, Casadaban LC, Hauck ZZ, van Breemen RB, Gaba RC. Pharmacokinetic study of conventional sorafenib chemoembolization in a rabbit VX2 liver tumor model. Diagnostic and Interventional Radiology (Ankara, Turkey). 21: 235-40. PMID 25835078 DOI: 10.5152/dir.2014.14394  0.764
2015 Huang K, Huang L, van Breemen RB. Detection of reactive metabolites using isotope-labeled glutathione trapping and simultaneous neutral loss and precursor ion scanning with ultra-high-pressure liquid chromatography triple quadruple mass spectrometry. Analytical Chemistry. 87: 3646-54. PMID 25774910 DOI: 10.1021/ac504737x  0.763
2015 Cantuti-Castelvetri L, Maravilla E, Marshall M, Tamayo T, D'auria L, Monge J, Jeffries J, Sural-Fehr T, Lopez-Rosas A, Li G, Garcia K, van Breemen R, Vite C, Garcia J, Bongarzone ER. Mechanism of neuromuscular dysfunction in Krabbe disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 1606-16. PMID 25632136 DOI: 10.1523/Jneurosci.2431-14.2015  0.524
2015 Pituch KC, Moyano AL, Lopez-Rosas A, Marottoli FM, Li G, Hu C, van Breemen R, Månsson JE, Givogri MI. Dysfunction of platelet-derived growth factor receptor α (PDGFRα) represses the production of oligodendrocytes from arylsulfatase A-deficient multipotential neural precursor cells. The Journal of Biological Chemistry. 290: 7040-53. PMID 25605750 DOI: 10.1074/Jbc.M115.636498  0.64
2014 Moyano AL, Li G, Lopez-Rosas A, Månsson JE, van Breemen RB, Givogri MI. Distribution of C16:0, C18:0, C24:1, and C24:0 sulfatides in central nervous system lipid rafts by quantitative ultra-high-pressure liquid chromatography tandem mass spectrometry. Analytical Biochemistry. 467: 31-9. PMID 25205652 DOI: 10.1016/J.Ab.2014.08.033  0.588
2014 van Breemen RB, Yuan Y, Banuvar S, Shulman LP, Qiu X, Alvarenga RF, Chen SN, Dietz BM, Bolton JL, Pauli GF, Krause E, Viana M, Nikolic D. Pharmacokinetics of prenylated hop phenols in women following oral administration of a standardized extract of hops. Molecular Nutrition & Food Research. 58: 1962-9. PMID 25045111 DOI: 10.1002/Mnfr.201400245  0.759
2014 Newsome AG, Culver CA, van Breemen RB. Nature's palette: the search for natural blue colorants. Journal of Agricultural and Food Chemistry. 62: 6498-511. PMID 24930897 DOI: 10.1021/jf501419q  0.771
2014 García ME, Nicotra VE, Oberti JC, Ríos-Luci C, León LG, Marler L, Li G, Pezzuto JM, van Breemen RB, Padrón JM, Hueso-Falcón I, Estévez-Braun A. Antiproliferative and quinone reductase-inducing activities of withanolides derivatives. European Journal of Medicinal Chemistry. 82: 68-81. PMID 24878636 DOI: 10.1016/J.Ejmech.2014.05.045  0.566
2014 Krause E, Yuan Y, Hajirahimkhan A, Dong H, Dietz BM, Nikolic D, Pauli GF, Bolton JL, van Breemen RB. Biological and chemical standardization of a hop (Humulus lupulus) botanical dietary supplement. Biomedical Chromatography : Bmc. 28: 729-34. PMID 24861737 DOI: 10.1002/Bmc.3177  0.648
2014 Nikoli? D, Li J, van Breemen RB. Metabolism of Nω -methylserotonin, a serotonergic constituent of black cohosh (Cimicifuga racemosa, L. (Nutt.)), by human liver microsomes. Biomedical Chromatography : Bmc. 28: 1647-51. PMID 24817649 DOI: 10.1002/Bmc.3197  0.505
2014 Vandenberg LN, Gerona RR, Kannan K, Taylor JA, van Breemen RB, Dickenson CA, Liao C, Yuan Y, Newbold RR, Padmanabhan V, Vom Saal FS, Woodruff TJ. A round robin approach to the analysis of bisphenol A (BPA) in human blood samples. Environmental Health : a Global Access Science Source. 13: 25. PMID 24690217 DOI: 10.1186/1476-069X-13-25  0.423
2014 Karalius VP, Harbison JE, Plange-Rhule J, van Breemen RB, Li G, Huang K, Durazo-Arvizu RA, Mora N, Dugas LR, Vail L, Tuchman NC, Forrester T, Luke A. Bisphenol A (BPA) Found in Humans and Water in Three Geographic Regions with Distinctly Different Levels of Economic Development. Environmental Health Insights. 8: 1-3. PMID 24453495 DOI: 10.4137/Ehi.S13130  0.613
2014 Prins GS, Hu WY, Shi GB, Hu DP, Majumdar S, Li G, Huang K, Nelles JL, Ho SM, Walker CL, Kajdacsy-Balla A, van Breemen RB. Bisphenol A promotes human prostate stem-progenitor cell self-renewal and increases in vivo carcinogenesis in human prostate epithelium. Endocrinology. 155: 805-17. PMID 24424067 DOI: 10.1210/en.2013-1955  0.623
2014 Smith BR, Santos MB, Marshall MS, Cantuti-Castelvetri L, Lopez-Rosas A, Li G, van Breemen R, Claycomb KI, Gallea JI, Celej MS, Crocker SJ, Givogri MI, Bongarzone ER. Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease. The Journal of Pathology. 232: 509-21. PMID 24415155 DOI: 10.1002/Path.4328  0.534
2014 Zhuge Y, Yuan Y, van Breemen R, Degrand M, Holian O, Yoder M, Lum H. Stimulated bronchial epithelial cells release bioactive lysophosphatidylcholine 16:0, 18:0, and 18:1. Allergy, Asthma & Immunology Research. 6: 66-74. PMID 24404396 DOI: 10.4168/Aair.2014.6.1.66  0.377
2014 Yoder M, Zhuge Y, Yuan Y, Holian O, Kuo S, van Breemen R, Thomas LL, Lum H. Bioactive lysophosphatidylcholine 16:0 and 18:0 are elevated in lungs of asthmatic subjects. Allergy, Asthma & Immunology Research. 6: 61-5. PMID 24404395 DOI: 10.4168/Aair.2014.6.1.61  0.383
2014 Yuan Y, Qiu X, Nikolić D, Chen SN, Huang K, Li G, Pauli GF, van Breemen RB. Inhibition of human cytochrome P450 enzymes by hops (Humulus lupulus) and hop prenylphenols. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 53: 55-61. PMID 24342125 DOI: 10.1016/J.Ejps.2013.12.003  0.795
2013 Andreani A, Leoni A, Locatelli A, Morigi R, Rambaldi M, Cervellati R, Greco E, Kondratyuk TP, Park EJ, Huang K, van Breemen RB, Pezzuto JM. Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles. European Journal of Medicinal Chemistry. 68: 412-21. PMID 23994869 DOI: 10.1016/J.Ejmech.2013.07.052  0.423
2013 Eilati E, Hales K, Zhuge Y, Ansenberger Fricano K, Yu R, van Breemen RB, Hales DB. Flaxseed enriched diet-mediated reduction in ovarian cancer severity is correlated to the reduction of prostaglandin E(2) in laying hen ovaries. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 89: 179-87. PMID 23978451 DOI: 10.1016/J.Plefa.2013.08.001  0.471
2013 Mo S, Dong L, Hurst WJ, van Breemen RB. Quantitative analysis of phytosterols in edible oils using APCI liquid chromatography-tandem mass spectrometry. Lipids. 48: 949-56. PMID 23884629 DOI: 10.1007/s11745-013-3813-3  0.683
2013 Hajirahimkhan A, Simmler C, Yuan Y, Anderson JR, Chen SN, Nikolić D, Dietz BM, Pauli GF, van Breemen RB, Bolton JL. Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms. Plos One. 8: e67947. PMID 23874474 DOI: 10.1371/Journal.Pone.0067947  0.433
2013 Yu R, Zhao G, Christman JW, Xiao L, Van Breemen RB. Method development and validation for ultra-high pressure liquid chromatography/tandem mass spectrometry determination of multiple prostanoids in biological samples. Journal of Aoac International. 96: 67-76. PMID 23513960 DOI: 10.5740/jaoacint.12-280  0.559
2013 Dietz BM, Hagos GK, Eskra JN, Wijewickrama GT, Anderson JR, Nikolic D, Guo J, Wright B, Chen SN, Pauli GF, van Breemen RB, Bolton JL. Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo. Molecular Nutrition & Food Research. 57: 1055-66. PMID 23512484 DOI: 10.1002/Mnfr.201200534  0.626
2013 Gaba RC, Yap FY, Martinez EM, Li Y, Guzman G, Parvinian A, van Breemen RB, Kumar N. Transarterial sorafenib chemoembolization: preliminary study of technical feasibility in a rabbit model. Journal of Vascular and Interventional Radiology : Jvir. 24: 744-50. PMID 23510657 DOI: 10.1016/j.jvir.2013.01.488  0.502
2013 Qiu X, Yuan Y, Vaishnav A, Tessel MA, Nonn L, van Breemen RB. Effects of lycopene on protein expression in human primary prostatic epithelial cells. Cancer Prevention Research (Philadelphia, Pa.). 6: 419-27. PMID 23483004 DOI: 10.1158/1940-6207.Capr-12-0364  0.705
2013 Conda-Sheridan M, Park EJ, Beck DE, Reddy PV, Nguyen TX, Hu B, Chen L, White JJ, van Breemen RB, Pezzuto JM, Cushman M. Design, synthesis, and biological evaluation of indenoisoquinoline rexinoids with chemopreventive potential. Journal of Medicinal Chemistry. 56: 2581-605. PMID 23472886 DOI: 10.1021/Jm400026K  0.773
2013 Yuan Y, Yu LF, Qiu X, Kozikowski AP, Van Breemen RB. Pharmacokinetics and brain penetration of LF-3-88, (2-[5-[5-(2(S)-azetidinylmethoxyl)-3-pyridyl]-3-isoxazolyl]ethanol), a selective α4β2-nAChR partial agonist and promising antidepressant Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 912: 38-42. PMID 23246847 DOI: 10.1016/J.Jchromb.2012.11.011  0.735
2013 Zhao G, Yu R, Deng J, Zhao Q, Li Y, Joo M, van Breemen RB, Christman JW, Xiao L. Pivotal role of reactive oxygen species in differential regulation of lipopolysaccharide-induced prostaglandins production in macrophages. Molecular Pharmacology. 83: 167-78. PMID 23071105 DOI: 10.1124/mol.112.080762  0.622
2013 Kabirov KK, Kapetanovic IM, Benbrook DM, Dinger N, Mankovskaya I, Zakharov A, Detrisac C, Pereira M, Martín-Jiménez T, Onua E, Banerjee A, van Breemen RB, Nikolić D, Chen L, Lyubimov AV. Oral toxicity and pharmacokinetic studies of SHetA2, a new chemopreventive agent, in rats and dogs. Drug and Chemical Toxicology. 36: 284-95. PMID 22947079 DOI: 10.3109/01480545.2012.710632  0.453
2012 Yuan Y, Qiu X, Nikolic D, Dahl JH, van Breemen RB. Method development and validation for ultra-high-pressure LC/MS/MS determination of hop prenylflavonoids in human serum. Journal of Aoac International. 95: 1744-9. PMID 23451393 DOI: 10.5740/Jaoacint.11-542  0.806
2012 Cinelli MA, Reddy PV, Lv PC, Liang JH, Chen L, Agama K, Pommier Y, van Breemen RB, Cushman M. Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I poisons. Journal of Medicinal Chemistry. 55: 10844-62. PMID 23215354 DOI: 10.1021/Jm300519W  0.521
2012 Zhu H, Lopez-Rosas A, Qiu X, Van Breemen RB, Bongarzone ER. Detection of the neurotoxin psychosine in samples of peripheral blood: application in diagnostics and follow-up of Krabbe disease. Archives of Pathology & Laboratory Medicine. 136: 709-10. PMID 22742542 DOI: 10.5858/Arpa.2011-0667-Le  0.604
2012 Chen L, Conda-Sheridan M, Reddy PV, Morrell A, Park EJ, Kondratyuk TP, Pezzuto JM, van Breemen RB, Cushman M. Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents. Journal of Medicinal Chemistry. 55: 5965-81. PMID 22712432 DOI: 10.1021/Jm3006806  0.522
2012 Baumgarten S, Gaba RC, van Breemen RB. Confirmation of drug delivery after liver chemoembolization: direct tissue doxorubicin measurement by UHPLC-MS-MS. Biomedical Chromatography : Bmc. 26: 1529-33. PMID 22454282 DOI: 10.1002/bmc.2727  0.792
2012 Kondratyuk TP, Park EJ, Yu R, van Breemen RB, Asolkar RN, Murphy BT, Fenical W, Pezzuto JM. Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents. Marine Drugs. 10: 451-64. PMID 22412812 DOI: 10.3390/Md10020451  0.467
2012 van Breemen RB, Dong L, Pajkovic ND. Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry of Carotenoids. International Journal of Mass Spectrometry. 312: 163-172. PMID 22408388 DOI: 10.1016/j.ijms.2011.07.030  0.788
2012 Nikolić D, Gödecke T, Chen SN, White J, Lankin DC, Pauli GF, van Breemen RB. Mass spectrometric dereplication of nitrogen-containing constituents of black cohosh (Cimicifuga racemosa L.). Fitoterapia. 83: 441-60. PMID 22178683 DOI: 10.1016/J.Fitote.2011.12.006  0.795
2012 Gaba RC, Baumgarten S, Omene BO, van Breemen RB, Garcia KD, Larson AC, Omary RA. Ethiodized oil uptake does not predict doxorubicin drug delivery after chemoembolization in VX2 liver tumors. Journal of Vascular and Interventional Radiology : Jvir. 23: 265-73. PMID 22178040 DOI: 10.1016/J.Jvir.2011.10.022  0.781
2012 Hu C, Nikolic D, Eggler AL, Mesecar AD, van Breemen RB. Screening for natural chemoprevention agents that modify human Keap1. Analytical Biochemistry. 421: 108-14. PMID 22074792 DOI: 10.1016/J.Ab.2011.10.028  0.686
2012 Al-Alem U, Gann PH, Dahl J, van Breemen RB, Mistry V, Lam PM, Evans MD, Van Horn L, Wright ME. Associations between functional polymorphisms in antioxidant defense genes and urinary oxidative stress biomarkers in healthy, premenopausal women. Genes & Nutrition. 7: 191-5. PMID 22068340 DOI: 10.1007/S12263-011-0257-3  0.774
2011 Yu R, Xiao L, Zhao G, Christman JW, van Breemen RB. Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2. The Journal of Pharmacology and Experimental Therapeutics. 339: 716-25. PMID 21865441 DOI: 10.1124/jpet.111.185405  0.505
2011 Li J, Gödecke T, Chen SN, Imai A, Lankin DC, Farnsworth NR, Pauli GF, van Breemen RB, Nikoli? D. In vitro metabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. PMID 21827327 DOI: 10.3109/00498254.2011.603385  0.521
2011 Kondratyuk TP, Park EJ, Marler LE, Ahn S, Yuan Y, Choi Y, Yu R, van Breemen RB, Sun B, Hoshino J, Cushman M, Jermihov KC, Mesecar AD, Grubbs CJ, Pezzuto JM. Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity. Molecular Nutrition & Food Research. 55: 1249-65. PMID 21714126 DOI: 10.1002/Mnfr.201100122  0.729
2011 Park EJ, Kondratyuk TP, Morrell A, Kiselev E, Conda-Sheridan M, Cushman M, Ahn S, Choi Y, White JJ, van Breemen RB, Pezzuto JM. Induction of retinoid X receptor activity and consequent upregulation of p21WAF1/CIP1 by indenoisoquinolines in MCF7 cells. Cancer Prevention Research (Philadelphia, Pa.). 4: 592-607. PMID 21464033 DOI: 10.1158/1940-6207.Capr-10-0004  0.784
2011 van Breemen RB, Sharifi R, Viana M, Pajkovic N, Zhu D, Yuan L, Yang Y, Bowen PE, Stacewicz-Sapuntzakis M. Antioxidant effects of lycopene in African American men with prostate cancer or benign prostate hyperplasia: a randomized, controlled trial. Cancer Prevention Research (Philadelphia, Pa.). 4: 711-8. PMID 21430075 DOI: 10.1158/1940-6207.Capr-10-0288  0.764
2011 Hu C, Eggler AL, Mesecar AD, van Breemen RB. Modification of keap1 cysteine residues by sulforaphane. Chemical Research in Toxicology. 24: 515-21. PMID 21391649 DOI: 10.1021/Tx100389R  0.478
2011 Castelvetri LC, Givogri MI, Zhu H, Smith B, Lopez-Rosas A, Qiu X, van Breemen R, Bongarzone ER. Axonopathy is a compounding factor in the pathogenesis of Krabbe disease. Acta Neuropathologica. 122: 35-48. PMID 21373782 DOI: 10.1007/S00401-011-0814-2  0.607
2011 Yang JH, Kondratyuk TP, Jermihov KC, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Huang R, Liu Y, Wang LQ, Mesecar AD, van Breemen RB, Pezzuto JM, et al. Bioactive compounds from the fern Lepisorus contortus. Journal of Natural Products. 74: 129-36. PMID 21261296 DOI: 10.1021/Np100373F  0.783
2011 Choi Y, Jermihov K, Nam SJ, Sturdy M, Maloney K, Qiu X, Chadwick LR, Main M, Chen SN, Mesecar AD, Farnsworth NR, Pauli GF, Fenical W, Pezzuto JM, van Breemen RB, ... van Breemen RR, et al. Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS. Analytical Chemistry. 83: 1048-52. PMID 21192729 DOI: 10.1021/Ac1028424  0.757
2011 Chen SN, Friesen JB, Webster D, Nikolic D, van Breemen RB, Wang ZJ, Fong HH, Farnsworth NR, Pauli GF. Phytoconstituents from Vitex agnus-castus fruits. Fitoterapia. 82: 528-33. PMID 21163339 DOI: 10.1016/j.fitote.2010.12.003  0.539
2011 van Breemen RB, Tao Y, Li W. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia. 82: 38-43. PMID 20837112 DOI: 10.1016/j.fitote.2010.09.004  0.697
2011 Cao H, Yu R, Tao Y, Nikolic D, van Breemen RB. Measurement of cyclooxygenase inhibition using liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 54: 230-5. PMID 20817448 DOI: 10.1016/J.Jpba.2010.08.001  0.791
2010 Marler L, Conda-Sheridan M, Cinelli MA, Morrell AE, Cushman M, Chen L, Huang K, Van Breemen R, Pezzuto JM. Cancer chemopreventive potential of aromathecins and phenazines, novel natural product derivatives. Anticancer Research. 30: 4873-82. PMID 21187465  0.628
2010 Dong L, Shion H, Davis RG, Terry-Penak B, Castro-Perez J, van Breemen RB. Collision cross-section determination and tandem mass spectrometric analysis of isomeric carotenoids using electrospray ion mobility time-of-flight mass spectrometry. Analytical Chemistry. 82: 9014-21. PMID 20939506 DOI: 10.1021/ac101974g  0.803
2010 Guo J, Peng D, Dai Q, Liao S, Wright BJ, van Breemen RB. Quantitative analysis of 3alpha,6alpha,24-trihydroxy-24,24-di(trifluoromethyl)-5beta-cholane, a potent synthetic steroidal liver X receptor agonist in plasma using liquid chromatography-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 1885-8. PMID 20627826 DOI: 10.1016/J.Jchromb.2010.05.009  0.466
2010 Hoshino J, Park EJ, Kondratyuk TP, Marler L, Pezzuto JM, van Breemen RB, Mo S, Li Y, Cushman M. Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. Journal of Medicinal Chemistry. 53: 5033-43. PMID 20527891 DOI: 10.1021/Jm100274C  0.547
2010 Wang Z, Chandrasena ER, Yuan Y, Peng KW, van Breemen RB, Thatcher GR, Bolton JL. Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens. Chemical Research in Toxicology. 23: 1365-73. PMID 20509668 DOI: 10.1021/Tx1001282  0.412
2010 Dahl JH, van Breemen RB. Rapid quantitative analysis of 8-iso-prostaglandin-F(2alpha) using liquid chromatography-tandem mass spectrometry and comparison with an enzyme immunoassay method. Analytical Biochemistry. 404: 211-6. PMID 20507827 DOI: 10.1016/j.ab.2010.05.023  0.807
2010 Bolca S, Li J, Nikolic D, Roche N, Blondeel P, Possemiers S, De Keukeleire D, Bracke M, Heyerick A, van Breemen RB, Depypere H. Disposition of hop prenylflavonoids in human breast tissue. Molecular Nutrition & Food Research. 54: S284-94. PMID 20486208 DOI: 10.1002/Mnfr.200900519  0.651
2010 Cao H, Yu R, Choi Y, Ma ZZ, Zhang H, Xiang W, Lee DY, Berman BM, Moudgil KD, Fong HH, van Breemen RB. Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation. Pharmacological Research. 61: 519-24. PMID 20188172 DOI: 10.1016/J.Phrs.2010.02.007  0.708
2010 Van Loo-Bouwman CA, Naber TH, van Breemen RB, Zhu D, Dicke H, Siebelink E, Hulshof PJ, Russel FG, Schaafsma G, West CE. Vitamin A equivalency and apparent absorption of beta-carotene in ileostomy subjects using a dual-isotope dilution technique. The British Journal of Nutrition. 103: 1836-43. PMID 20132586 DOI: 10.1017/S0007114509993849  0.47
2010 Yang JH, Kondratyuk TP, Marler LE, Qiu X, Choi Y, Cao H, Yu R, Sturdy M, Pegan S, Liu Y, Wang LQ, Mesecar AD, Van Breemen RB, Pezzuto JM, Fong HH, et al. Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata. Phytochemistry. 71: 641-7. PMID 20100622 DOI: 10.1016/J.Phytochem.2010.01.002  0.789
2010 Cuendet M, Guo J, Luo Y, Chen S, Oteham CP, Moon RC, van Breemen RB, Marler LE, Pezzuto JM. Cancer chemopreventive activity and metabolism of isoliquiritigenin, a compound found in licorice. Cancer Prevention Research (Philadelphia, Pa.). 3: 221-32. PMID 20068129 DOI: 10.1158/1940-6207.Capr-09-0049  0.481
2010 van Breemen RB, Liang W, Banuvar S, Shulman LP, Pang Y, Tao Y, Nikolic D, Krock KM, Fabricant DS, Chen SN, Hedayat S, Bolton JL, Pauli GF, Piersen CE, Krause EC, et al. Pharmacokinetics of 23-epi-26-deoxyactein in women after oral administration of a standardized extract of black cohosh. Clinical Pharmacology and Therapeutics. 87: 219-25. PMID 20032972 DOI: 10.1038/Clpt.2009.251  0.665
2009 He B, Velaparthi S, Pieffet G, Pennington C, Mahesh A, Holzle DL, Brunsteiner M, van Breemen R, Blond SY, Petukhov PA. Binding ensemble profiling with photoaffinity labeling (BEProFL) approach: mapping the binding poses of HDAC8 inhibitors. Journal of Medicinal Chemistry. 52: 7003-13. PMID 19886628 DOI: 10.1021/Jm9005077  0.673
2009 Tao Y, Li W, Liang W, Van Breemen RB. Identification and quantification of gingerols and related compounds in ginger dietary supplements using high-performance liquid chromatography-tandem mass spectrometry. Journal of Agricultural and Food Chemistry. 57: 10014-21. PMID 19817455 DOI: 10.1021/Jf9020224  0.793
2009 Geller SE, Shulman LP, van Breemen RB, Banuvar S, Zhou Y, Epstein G, Hedayat S, Nikolic D, Krause EC, Piersen CE, Bolton JL, Pauli GF, Farnsworth NR. Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms: a randomized controlled trial. Menopause (New York, N.Y.). 16: 1156-66. PMID 19609225 DOI: 10.1097/Gme.0B013E3181Ace49B  0.472
2009 Calderón AI, Wright BJ, Hurst WJ, van Breemen RB. Screening antioxidants using LC-MS: case study with cocoa. Journal of Agricultural and Food Chemistry. 57: 5693-9. PMID 19489609 DOI: 10.1021/jf9014203  0.714
2009 White AB, Givogri MI, Lopez-Rosas A, Cao H, van Breemen R, Thinakaran G, Bongarzone ER. Psychosine accumulates in membrane microdomains in the brain of krabbe patients, disrupting the raft architecture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6068-77. PMID 19439584 DOI: 10.1523/Jneurosci.5597-08.2009  0.461
2009 Gödecke T, Lankin DC, Nikolic D, Chen SN, van Breemen RB, Farnsworth NR, Pauli GF. Guanidine alkaloids and Pictet-Spengler adducts from black cohosh (Cimicifuga racemosa). Journal of Natural Products. 72: 433-7. PMID 19220011 DOI: 10.1021/np8006952  0.547
2009 Wang Z, Wijewickrama GT, Peng KW, Dietz BM, Yuan L, van Breemen RB, Bolton JL, Thatcher GR. Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus. The Journal of Biological Chemistry. 284: 8633-42. PMID 19158089 DOI: 10.1074/Jbc.M807860200  0.434
2009 Gödecke T, Nikolic D, Lankin DC, Chen SN, Powell SL, Dietz B, Bolton JL, van Breemen RB, Farnsworth NR, Pauli GF. Phytochemistry of cimicifugic acids and associated bases in Cimicifuga racemosa root extracts. Phytochemical Analysis : Pca. 20: 120-33. PMID 19140115 DOI: 10.1002/Pca.1106  0.515
2009 Van Loo-Bouwman CA, West CE, van Breemen RB, Zhu D, Siebelink E, Versloot P, Hulshof PJ, van Lieshout M, Russel FG, Schaafsma G, Naber TH. Vitamin A equivalency of beta-carotene in healthy adults: limitation of the extrinsic dual-isotope dilution technique to measure matrix effect. The British Journal of Nutrition. 101: 1837-45. PMID 19025719 DOI: 10.1017/S0007114508131762  0.471
2009 Qin Z, Kastrati I, Ashgodom RT, Lantvit DD, Overk CR, Choi Y, van Breemen RB, Bolton JL, Thatcher GR. Structural modulation of oxidative metabolism in design of improved benzothiophene selective estrogen receptor modulators. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 161-9. PMID 18936111 DOI: 10.1124/Dmd.108.023408  0.503
2008 Powell SL, Gödecke T, Nikolic D, Chen SN, Ahn S, Dietz B, Farnsworth NR, van Breemen RB, Lankin DC, Pauli GF, Bolton JL. In vitro serotonergic activity of black cohosh and identification of N(omega)-methylserotonin as a potential active constituent. Journal of Agricultural and Food Chemistry. 56: 11718-26. PMID 19049296 DOI: 10.1021/Jf803298Z  0.623
2008 Dietz BM, Liu D, Hagos GK, Yao P, Schinkovitz A, Pro SM, Deng S, Farnsworth NR, Pauli GF, van Breemen RB, Bolton JL. Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1. Chemical Research in Toxicology. 21: 1939-48. PMID 18808158 DOI: 10.1021/Tx8001274  0.753
2008 Guo J, Liu A, Cao H, Luo Y, Pezzuto JM, van Breemen RB. Biotransformation of the chemopreventive agent 2',4',4-trihydroxychalcone (isoliquiritigenin) by UDP-glucuronosyltransferases. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2104-12. PMID 18653743 DOI: 10.1124/Dmd.108.021857  0.731
2008 Overk CR, Guo J, Chadwick LR, Lantvit DD, Minassi A, Appendino G, Chen SN, Lankin DC, Farnsworth NR, Pauli GF, van Breemen RB, Bolton JL. In vivo estrogenic comparisons of Trifolium pratense (red clover) Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin. Chemico-Biological Interactions. 176: 30-9. PMID 18619951 DOI: 10.1016/J.Cbi.2008.06.005  0.371
2008 van Breemen RB, Pajkovic N. Multitargeted therapy of cancer by lycopene. Cancer Letters. 269: 339-51. PMID 18585855 DOI: 10.1016/J.Canlet.2008.05.016  0.754
2008 Chen SN, Turner A, Jaki BU, Nikolic D, van Breemen RB, Friesen JB, Pauli GF. An experimental implementation of chemical subtraction. Journal of Pharmaceutical and Biomedical Analysis. 46: 692-8. PMID 18234463 DOI: 10.1016/J.Jpba.2007.12.014  0.563
2008 Choi Y, van Breemen RB. Development of a screening assay for ligands to the estrogen receptor based on magnetic microparticles and LC-MS. Combinatorial Chemistry & High Throughput Screening. 11: 1-6. PMID 18220538 DOI: 10.2174/138620708783398340  0.509
2008 Guo J, Liu D, Nikolic D, Zhu D, Pezzuto JM, van Breemen RB. In vitro metabolism of isoliquiritigenin by human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 461-8. PMID 18006650 DOI: 10.1124/Dmd.107.018721  0.794
2008 Cao H, Xiao L, Park G, Wang X, Azim AC, Christman JW, van Breemen RB. An improved LC-MS/MS method for the quantification of prostaglandins E(2) and D(2) production in biological fluids. Analytical Biochemistry. 372: 41-51. PMID 17976507 DOI: 10.1016/J.Ab.2007.08.041  0.526
2007 Goo YA, Li Z, Pajkovic N, Shaffer S, Taylor G, Chen J, Campbell D, Arnstein L, Goodlett DR, van Breemen RB. Systematic investigation of lycopene effects in LNCaP cells by use of novel large-scale proteomic analysis software. Proteomics. Clinical Applications. 1: 513-523. PMID 20740054 DOI: 10.1002/Prca.200600511  0.774
2007 Galbiati F, Basso V, Cantuti L, Givogri MI, Lopez-Rosas A, Perez N, Vasu C, Cao H, van Breemen R, Mondino A, Bongarzone ER. Autonomic denervation of lymphoid organs leads to epigenetic immune atrophy in a mouse model of Krabbe disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13730-8. PMID 18077684 DOI: 10.1523/Jneurosci.3379-07.2007  0.441
2007 Azim AC, Wang X, Park GY, Sadikot RT, Cao H, Mathew B, Atchison M, van Breemen RB, Joo M, Christman JW. NF-kappaB-inducing kinase regulates cyclooxygenase 2 gene expression in macrophages by phosphorylation of PU.1. Journal of Immunology (Baltimore, Md. : 1950). 179: 7868-75. PMID 18025233 DOI: 10.4049/Jimmunol.179.11.7868  0.447
2007 Liu D, Guo J, Luo Y, Broderick DJ, Schimerlik MI, Pezzuto JM, van Breemen RB. Screening for ligands of human retinoid X receptor-alpha using ultrafiltration mass spectrometry. Analytical Chemistry. 79: 9398-402. PMID 17997524 DOI: 10.1021/Ac701701K  0.79
2007 Luo Y, Eggler AL, Liu D, Liu G, Mesecar AD, van Breemen RB. Sites of alkylation of human Keap1 by natural chemoprevention agents. Journal of the American Society For Mass Spectrometry. 18: 2226-32. PMID 17980616 DOI: 10.1016/J.Jasms.2007.09.015  0.802
2007 Eggler AL, Luo Y, van Breemen RB, Mesecar AD. Identification of the highly reactive cysteine 151 in the chemopreventive agent-sensor Keap1 protein is method-dependent. Chemical Research in Toxicology. 20: 1878-84. PMID 17935299 DOI: 10.1021/Tx700217C  0.321
2007 Pang Y, Nikolic D, Zhu D, Chadwick LR, Pauli GF, Farnsworth NR, van Breemen RB. Binding of the hop (Humulus lupulus L.) chalcone xanthohumol to cytosolic proteins in Caco-2 intestinal epithelial cells. Molecular Nutrition & Food Research. 51: 872-9. PMID 17579893 DOI: 10.1002/Mnfr.200600252  0.725
2007 Azim AC, Cao H, Gao X, Joo M, Malik AB, van Breemen RB, Sadikot RT, Park G, Christman JW. Regulation of cyclooxygenase-2 expression by small GTPase Rac2 in bone marrow macrophages. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L668-73. PMID 17575012 DOI: 10.1152/Ajplung.00043.2007  0.443
2007 Chen SN, Lankin DC, Nikolic D, Fabricant DS, Lu ZZ, Ramirez B, van Breemen RB, Fong HH, Farnsworth NR, Pauli GF. Chlorination diversifies Cimicifuga racemosa triterpene glycosides. Journal of Natural Products. 70: 1016-23. PMID 17555351 DOI: 10.1021/np0700319  0.545
2007 Li W, Xu X, Zhang H, Ma C, Fong H, van Breemen R, Fitzloff J. Secondary metabolites from Andrographis paniculata. Chemical & Pharmaceutical Bulletin. 55: 455-8. PMID 17329890 DOI: 10.1248/Cpb.55.455  0.602
2007 Turner A, Chen SN, Nikolic D, van Breemen R, Farnsworth NR, Pauli GF. Coumaroyl iridoids and a depside from cranberry (Vaccinium macrocarpon). Journal of Natural Products. 70: 253-8. PMID 17269823 DOI: 10.1021/Np060260F  0.511
2007 Mathew B, Park GY, Cao H, Azim AC, Wang X, Van Breemen RB, Sadikot RT, Christman JW. Inhibitory kappaB kinase 2 activates airway epithelial cells to stimulate bone marrow macrophages. American Journal of Respiratory Cell and Molecular Biology. 36: 562-72. PMID 17204585 DOI: 10.1165/Rcmb.2006-0245Oc  0.443
2006 Deng S, Chen SN, Lu J, Wang ZJ, Nikolic D, van Breemen RB, Santarsiero BD, Mesecar A, Fong HH, Farnsworth NR, Pauli GF. GABAergic phthalide dimers from Angelica sinensis (Oliv.) Diels. Phytochemical Analysis : Pca. 17: 398-405. PMID 17144247 DOI: 10.1002/Pca.937  0.544
2006 Wang Z, Yuan H, Nikolic D, Van Breemen RB, Silverman RB. (+/-)-(1S,2R,5S)-5-Amino-2-fluorocyclohex-3-enecarboxylic acid. A potent GABA aminotransferase inactivator that irreversibly inhibits via an elimination-aromatization pathway. Biochemistry. 45: 14513-22. PMID 17128990 DOI: 10.1021/Bi061592M  0.483
2006 Liu A, Pajkovic N, Pang Y, Zhu D, Calamini B, Mesecar AL, van Breemen RB. Absorption and subcellular localization of lycopene in human prostate cancer cells. Molecular Cancer Therapeutics. 5: 2879-85. PMID 17121935 DOI: 10.1158/1535-7163.Mct-06-0373  0.774
2006 Melse-Boonstra A, Verhoef P, West CE, van Rhijn JA, van Breemen RB, Lasaroms JJ, Garbis SD, Katan MB, Kok FJ. A dual-isotope-labeling method of studying the bioavailability of hexaglutamyl folic acid relative to that of monoglutamyl folic acid in humans by using multiple orally administered low doses. The American Journal of Clinical Nutrition. 84: 1128-33. PMID 17093166 DOI: 10.1093/Ajcn/84.5.1128  0.571
2006 Kapetanovic IM, Krishnaraj R, Martin-Jimenez T, Yuan L, van Breemen RB, Lyubimov A. Effects of oral dosing paradigms (gavage versus diet) on pharmacokinetics and pharmacodynamics. Chemico-Biological Interactions. 164: 68-75. PMID 17027946 DOI: 10.1016/J.Cbi.2006.08.019  0.445
2006 Zhu D, Wang Y, Pang Y, Liu A, Guo J, Bouwman CA, West CE, van Breemen RB. Quantitative analyses of beta-carotene and retinol in serum and feces in support of clinical bioavailability studies. Rapid Communications in Mass Spectrometry : Rcm. 20: 2427-32. PMID 16841362 DOI: 10.1002/Rcm.2601  0.771
2006 Nikolic D, Li Y, Chadwick LR, van Breemen RB. In vitro studies of intestinal permeability and hepatic and intestinal metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus L.). Pharmaceutical Research. 23: 864-72. PMID 16715376 DOI: 10.1007/s11095-006-9902-8  0.606
2006 Mallavadhani UV, Narasimhan K, Sudhakar AV, Mahapatra A, Li W, van Breemen RB. Three new pentacyclic triterpenes and some flavonoids from the fruits of an Indian Ayurvedic plant Dendrophthoe falcata and their estrogen receptor binding activity. Chemical & Pharmaceutical Bulletin. 54: 740-4. PMID 16651782 DOI: JST.JSTAGE/cpb/54.740  0.583
2006 Deng S, Chen SN, Yao P, Nikolic D, van Breemen RB, Bolton JL, Fong HH, Farnsworth NR, Pauli GF. Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. Journal of Natural Products. 69: 536-41. PMID 16643021 DOI: 10.1021/Np050301S  0.523
2006 Guo J, Nikolic D, Chadwick LR, Pauli GF, van Breemen RB. Identification of human hepatic cytochrome P450 enzymes involved in the metabolism of 8-prenylnaringenin and isoxanthohumol from hops (Humulus lupulus L.). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1152-9. PMID 16611861 DOI: 10.1124/dmd.105.008250  0.609
2006 Booth NL, Overk CR, Yao P, Burdette JE, Nikolic D, Chen SN, Bolton JL, van Breemen RB, Pauli GF, Farnsworth NR. The chemical and biologic profile of a red clover (Trifolium pratense L.) phase II clinical extract. Journal of Alternative and Complementary Medicine (New York, N.Y.). 12: 133-9. PMID 16566672 DOI: 10.1089/Acm.2006.12.133  0.588
2005 van Breemen RB, Li Y. Caco-2 cell permeability assays to measure drug absorption. Expert Opinion On Drug Metabolism & Toxicology. 1: 175-85. PMID 16922635 DOI: 10.1517/17425255.1.2.175  0.528
2005 Cheng X, van Breemen RB. Mass spectrometry-based screening for inhibitors of beta-amyloid protein aggregation. Analytical Chemistry. 77: 7012-5. PMID 16255603 DOI: 10.1021/Ac050556A  0.506
2005 Li Y, Yang X, van Breemen RB, Bolton JL. Characterization of two new variants of human catechol O-methyltransferase in vitro. Cancer Letters. 230: 81-9. PMID 16253764 DOI: 10.1016/J.Canlet.2004.12.022  0.368
2005 Liu G, Eggler AL, Dietz BM, Mesecar AD, Bolton JL, Pezzuto JM, van Breemen RB. Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1. Analytical Chemistry. 77: 6407-14. PMID 16194107 DOI: 10.1021/Ac050892R  0.532
2005 Liu J, Li Q, Yang X, van Breemen RB, Bolton JL, Thatcher GR. Analysis of protein covalent modification by xenobiotics using a covert oxidatively activated tag: raloxifene proof-of-principle study. Chemical Research in Toxicology. 18: 1485-96. PMID 16167842 DOI: 10.1021/Tx0501738  0.394
2005 Fabricant DS, Nikolic D, Lankin DC, Chen SN, Jaki BU, Krunic A, van Breemen RB, Fong HH, Farnsworth NR, Pauli GF. Cimipronidine, a cyclic guanidine alkaloid from Cimicifuga racemosa. Journal of Natural Products. 68: 1266-70. PMID 16124775 DOI: 10.1021/np050066d  0.532
2005 Dietz BM, Kang YH, Liu G, Eggler AL, Yao P, Chadwick LR, Pauli GF, Farnsworth NR, Mesecar AD, van Breemen RB, Bolton JL. Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase. Chemical Research in Toxicology. 18: 1296-305. PMID 16097803 DOI: 10.1021/Tx050058X  0.495
2005 Overk CR, Yao P, Chadwick LR, Nikolic D, Sun Y, Cuendet MA, Deng Y, Hedayat AS, Pauli GF, Farnsworth NR, van Breemen RB, Bolton JL. Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense). Journal of Agricultural and Food Chemistry. 53: 6246-53. PMID 16076101 DOI: 10.1021/Jf050448P  0.671
2005 Eggler AL, Liu G, Pezzuto JM, van Breemen RB, Mesecar AD. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proceedings of the National Academy of Sciences of the United States of America. 102: 10070-5. PMID 16006525 DOI: 10.1073/Pnas.0502402102  0.447
2005 Li Y, Yang X, Chang M, Yager JD, van Breemen RB, Bolton JL. Functional and structural comparisons of cysteine residues in the Val108 wild type and Met108 variant of human soluble catechol O-methyltransferase. Chemico-Biological Interactions. 152: 151-63. PMID 15840388 DOI: 10.1016/J.Cbi.2005.03.001  0.364
2005 Constantinou AI, White BE, Tonetti D, Yang Y, Liang W, Li W, van Breemen RB. The soy isoflavone daidzein improves the capacity of tamoxifen to prevent mammary tumours. European Journal of Cancer (Oxford, England : 1990). 41: 647-54. PMID 15737570 DOI: 10.1016/J.Ejca.2004.12.005  0.734
2005 Sun Y, Li W, Fitzloff JF, van Breemen RB. Liquid chromatography/electrospray tandem mass spectrometry of terpenoid lactones in Ginkgo biloba. Journal of Mass Spectrometry : Jms. 40: 373-9. PMID 15712369 DOI: 10.1002/Jms.795  0.751
2005 Nikolic D, Li Y, Chadwick LR, Pauli GF, van Breemen RB. Metabolism of xanthohumol and isoxanthohumol, prenylated flavonoids from hops (Humulus lupulus L.), by human liver microsomes. Journal of Mass Spectrometry : Jms. 40: 289-99. PMID 15712367 DOI: 10.1002/jms.753  0.642
2005 Sun Y, Gu C, Liu X, Liang W, Yao P, Bolton JL, van Breemen RB. Ultrafiltration tandem mass spectrometry of estrogens for characterization of structure and affinity for human estrogen receptors. Journal of the American Society For Mass Spectrometry. 16: 271-9. PMID 15694777 DOI: 10.1016/J.Jasms.2004.11.002  0.674
2005 Zhu Y, Nikolic D, Van Breemen RB, Silverman RB. Mechanism of inactivation of inducible nitric oxide synthase by amidines. Irreversible enzyme inactivation without inactivator modification. Journal of the American Chemical Society. 127: 858-68. PMID 15656623 DOI: 10.1021/Ja0445645  0.535
2005 Kobayashi T, Yang X, Walker LA, Van Breemen RB, Solaro RJ. A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: Identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C Journal of Molecular and Cellular Cardiology. 38: 213-218. PMID 15623438 DOI: 10.1016/J.Yjmcc.2004.10.014  0.328
2004 Chadwick LR, Nikolic D, Burdette JE, Overk CR, Bolton JL, van Breemen RB, Fröhlich R, Fong HH, Farnsworth NR, Pauli GF. Estrogens and congeners from spent hops (Humulus lupulus). Journal of Natural Products. 67: 2024-32. PMID 15620245 DOI: 10.1021/Np049783I  0.544
2004 Booth NL, Nikolic D, van Breemen RB, Geller SE, Banuvar S, Shulman LP, Farnsworth NR. Confusion regarding anticoagulant coumarins in dietary supplements. Clinical Pharmacology and Therapeutics. 76: 511-6. PMID 15592321 DOI: 10.1016/j.clpt.2004.08.023  0.465
2004 Mariappan SV, Cheng X, van Breemen RB, Silks LA, Gupta G. Analysis of GAA/TTC DNA triplexes using nuclear magnetic resonance and electrospray ionization mass spectrometry. Analytical Biochemistry. 334: 216-26. PMID 15494127 DOI: 10.1016/J.Ab.2004.07.036  0.501
2004 Li Y, Grubjesic S, Nikolic D, Zhu D, Kosmeder JW, Moriarty RM, Pezzuto JM, Van Breemen RB. In vitro assessment of intestinal permeability and hepatic metabolism of 4'-bromoflavone, a promising cancer chemopreventive agent. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 34: 535-47. PMID 15277014 DOI: 10.1080/00498250410001713159  0.556
2004 Yu L, Liu H, Li W, Zhang F, Luckie C, van Breemen RB, Thatcher GR, Bolton JL. Oxidation of raloxifene to quinoids: potential toxic pathways via a diquinone methide and o-quinones. Chemical Research in Toxicology. 17: 879-88. PMID 15257612 DOI: 10.1021/Tx0342722  0.618
2004 Piersen CE, Booth NL, Sun Y, Liang W, Burdette JE, van Breemen RB, Geller SE, Gu C, Banuvar S, Shulman LP, Bolton JL, Farnsworth NR. Chemical and biological characterization and clinical evaluation of botanical dietary supplements: a phase I red clover extract as a model. Current Medicinal Chemistry. 11: 1361-74. PMID 15180571 DOI: 10.2174/0929867043365134  0.668
2004 Li Y, Yao J, Chang M, Nikolic D, Yu L, Yager JD, Mesecar AD, van Breemen RB, Bolton JL. Equine catechol estrogen 4-hydroxyequilenin is a more potent inhibitor of the variant form of catechol-O-methyltransferase. Chemical Research in Toxicology. 17: 512-20. PMID 15089093 DOI: 10.1021/Tx0342464  0.516
2004 Nikolic D, van Breemen RB. New metabolic pathways for flavanones catalyzed by rat liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 387-97. PMID 15039291 DOI: 10.1124/dmd.32.4.387  0.549
2004 Yang X, Wu H, Kobayashi T, Solaro RJ, van Breemen RB. Enhanced ionization of phosphorylated peptides during MALDI TOF mass spectrometry. Analytical Chemistry. 76: 1532-6. PMID 14987115 DOI: 10.1021/Ac035203V  0.556
2004 Liu J, Burdette JE, Sun Y, Deng S, Schlecht SM, Zheng W, Nikolic D, Mahady G, van Breemen RB, Fong HH, Pezzuto JM, Bolton JL, Farnsworth NR. Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry). Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 11: 18-23. PMID 14974442 DOI: 10.1078/0944-7113-00331  0.519
2004 Nikolic D, Li Y, Chadwick LR, Grubjesic S, Schwab P, Metz P, van Breemen RB. Metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 272-9. PMID 14744951 DOI: 10.1124/Dmd.32.2.272  0.634
2004 Li W, Sun Y, Van Breemen RB, Fitzloff JF. Evaluation of major caffeic acid derivatives in Echinacea purpurea dietary supplements by HPLC with photodiode array detection and electrospray mass spectrometry Journal of Liquid Chromatography and Related Technologies. 27: 2507-2529. DOI: 10.1081/Jlc-200028369  0.546
2003 Li Y, Shin YG, Yu C, Kosmeder JW, Hirschelman WH, Pezzuto JM, van Breemen RB. Increasing the throughput and productivity of Caco-2 cell permeability assays using liquid chromatography-mass spectrometry: application to resveratrol absorption and metabolism. Combinatorial Chemistry & High Throughput Screening. 6: 757-67. PMID 14683481 DOI: 10.2174/138620703771826865  0.685
2003 Lu X, Nikolic D, Mitchell DJ, van Breemen RB, Mersfelder JA, Hille R, Silverman RB. A mechanism for substrate-Induced formation of 6-hydroxyflavin mononucleotide catalyzed by C30A trimethylamine dehydrogenase. Bioorganic & Medicinal Chemistry Letters. 13: 4129-32. PMID 14592522 DOI: 10.1016/J.Bmcl.2003.07.032  0.468
2003 Lyons MM, Yu C, Toma RB, Cho SY, Reiboldt W, Lee J, van Breemen RB. Resveratrol in raw and baked blueberries and bilberries. Journal of Agricultural and Food Chemistry. 51: 5867-70. PMID 13129286 DOI: 10.1021/Jf034150F  0.808
2003 Cheng X, Shin YG, Levine BS, Smith AC, Tomaszewski JE, van Breemen RB. Quantitative analysis of betulinic acid in mouse, rat and dog plasma using electrospray liquid chromatography/mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 17: 2089-92. PMID 12955738 DOI: 10.1002/Rcm.1155  0.562
2003 Su BN, Park EJ, Nikolic D, Schunke Vigo J, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora. Journal of Natural Products. 66: 1089-93. PMID 12932130 DOI: 10.1021/Np030081N  0.521
2003 Van Lieshout M, West CE, Van De Bovenkamp P, Wang Y, Sun Y, Van Breemen RB, Muhilal DP, Verhoeven MA, Creemers AF, Lugtenburg J. Extraction of carotenoids from feces, enabling the bioavailability of beta-carotene to be studied in Indonesian children. Journal of Agricultural and Food Chemistry. 51: 5123-30. PMID 12903979 DOI: 10.1021/Jf0300240  0.503
2003 Kouloumbos VN, Tsipi DF, Hiskia AE, Nikolic D, van Breemen RB. Identification of photocatalytic degradation products of diazinon in TiO2 aqueous suspensions using GC/MS/MS and LC/MS with quadrupole time-of-flight mass spectrometry. Journal of the American Society For Mass Spectrometry. 14: 803-17. PMID 12892905 DOI: 10.1016/S1044-0305(03)00333-7  0.584
2003 Johnson BM, Van Breemen RB. In vitro formation of quinoid metabolites of the dietary supplement Cimicifuga racemosa (black cohosh) Chemical Research in Toxicology. 16: 838-846. PMID 12870886  0.627
2003 Johnson BM, Qiu SX, Zhang S, Zhang F, Burdette JE, Yu L, Bolton JL, van Breemen RB. Identification of novel electrophilic metabolites of piper methysticum Forst (Kava). Chemical Research in Toxicology. 16: 733-40. PMID 12807356 DOI: 10.1021/Tx020113R  0.64
2003 Yao J, Li Y, Chang M, Wu H, Yang X, Goodman JE, Liu X, Liu H, Mesecar AD, Van Breemen RB, Yager JD, Bolton JL. Catechol estrogen 4-hydroxyequilenin is a substrate and an inhibitor of catechol-O-methyltransferase. Chemical Research in Toxicology. 16: 668-75. PMID 12755597 DOI: 10.1021/Tx0340549  0.582
2003 Gu JQ, Li W, Kang YH, Su BN, Fong HHS, Van Breemen RB, Pezzuto JM, Kinghorn AD. Minor withanolides from Physalis philadelphica: Structures, quinone reductase induction activities, and liquid chromatography (LC)-MS-MS investigation as artifacts Chemical and Pharmaceutical Bulletin. 51: 530-539. PMID 12736452 DOI: 10.1248/Cpb.51.530  0.67
2003 Li W, Sun Y, Liang W, Fitzloff JF, van Breemen RB. Identification of caffeic acid derivatives in Actea racemosa (Cimicifuga racemosa, black cohosh) by liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 17: 978-82. PMID 12717772 DOI: 10.1002/Rcm.1008  0.788
2003 Su BN, Park EJ, Nikolic D, Santarsiero BD, Mesecar AD, Vigo JS, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity. The Journal of Organic Chemistry. 68: 2350-61. PMID 12636402 DOI: 10.1021/Jo020542U  0.529
2003 Fang L, Pajkovic N, Wang Y, Gu C, van Breemen RB. Quantitative analysis of lycopene isomers in human plasma using high-performance liquid chromatography-tandem mass spectrometry. Analytical Chemistry. 75: 812-7. PMID 12622371 DOI: 10.1021/Ac026118A  0.81
2003 Yu C, Shin YG, Kosmeder JW, Pezzuto JM, van Breemen RB. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Communications in Mass Spectrometry : Rcm. 17: 307-13. PMID 12569440 DOI: 10.1002/Rcm.918  0.563
2003 Li W, Sun Y, Joseph J, Fitzloff JF, Fong HH, van Breemen RB. p-Hydroxybenzoic acid alkyl esters in Andrographis paniculata herbs, commercial extracts, and formulated products. Journal of Agricultural and Food Chemistry. 51: 524-9. PMID 12517121 DOI: 10.1021/Jf0258712  0.742
2002 Yu C, Shin YG, Chow A, Li Y, Kosmeder JW, Lee YS, Hirschelman WH, Pezzuto JM, Mehta RG, van Breemen RB. Human, rat, and mouse metabolism of resveratrol. Pharmaceutical Research. 19: 1907-14. PMID 12523673 DOI: 10.1023/A:1021414129280  0.619
2002 Yang Y, Nikolic D, Swanson SM, van Breemen RB. Quantitative determination of N7-methyldeoxyguanosine and O6-methyldeoxyguanosine in DNA by LC-UV-MS-MS. Analytical Chemistry. 74: 5376-82. PMID 12403596 DOI: 10.1021/Ac020235O  0.64
2002 Johnson BM, Nikolic D, van Breemen RB. Applications of pulsed ultrafiltration-mass spectrometry. Mass Spectrometry Reviews. 21: 76-86. PMID 12373745 DOI: 10.1002/mas.10020  0.722
2002 Li W, Sun Y, Fitzloff JF, van Breemen RB. Evaluation of commercial ginkgo and echinacea dietary supplements for colchicine using liquid chromatography-tandem mass spectrometry. Chemical Research in Toxicology. 15: 1174-8. PMID 12230411 DOI: 10.1021/Tx025559M  0.756
2002 Liu X, Yao J, Pisha E, Yang Y, Hua Y, van Breemen RB, Bolton JL. Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha. Chemical Research in Toxicology. 15: 512-9. PMID 11952337 DOI: 10.1021/Tx0101649  0.783
2002 van Breemen RB, Xu X, Viana MA, Chen L, Stacewicz-Sapuntzakis M, Duncan C, Bowen PE, Sharifi R. Liquid chromatography-mass spectrometry of cis- and all-trans-lycopene in human serum and prostate tissue after dietary supplementation with tomato sauce. Journal of Agricultural and Food Chemistry. 50: 2214-9. PMID 11929273 DOI: 10.1021/jf0110351  0.548
2002 Wang Y, Catana F, Yang Y, Roderick R, van Breemen RB. An LC-MS method for analyzing total resveratrol in grape juice, cranberry juice, and in wine. Journal of Agricultural and Food Chemistry. 50: 431-5. PMID 11804508 DOI: 10.1021/Jf010812U  0.536
2002 Papadantonakis GA, Tranter R, Brezinsky K, Yang Y, Van Breemen RB, LeBreton PR. Low-energy, low-yield photoionization, and production of 8-oxo-2′-deoxyguanosine and guanine from 2′-deoxyguanosine Journal of Physical Chemistry B. 106: 7704-7712. DOI: 10.1021/Jp020649L  0.381
2002 Pajkovic N, Nikolic D, Tolga U, Manev H, Van Breemen RB. LC-MS-MS quantitation of N-acetylserotonin in neuronal tissues and cell culture media Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 571-572.  0.768
2002 Yang Y, Li Y, Nikolic D, Hong M, Swanson SM, Pajkovic N, Van Breemen RB. Quantitative determination of N-methyl-N-nitrosourea-induced in vitro and in vivo DNA methylation by LC-UV-MS-MS Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 423-424.  0.771
2001 Garbis SD, Melse-Boonstra A, West CE, van Breemen RB. Determination of folates in human plasma using hydrophilic interaction chromatography-tandem mass spectrometry. Analytical Chemistry. 73: 5358-64. PMID 11816560 DOI: 10.1021/Ac010741Y  0.64
2001 Zhang F, Swanson SM, van Breemen RB, Liu X, Yang Y, Gu C, Bolton JL. Equine estrogen metabolite 4-hydroxyequilenin induces DNA damage in the rat mammary tissues: formation of single-strand breaks, apurinic sites, stable adducts, and oxidized bases. Chemical Research in Toxicology. 14: 1654-9. PMID 11743748 DOI: 10.1021/Tx010158C  0.471
2001 Yao D, Zhang F, Yu L, Yang Y, van Breemen RB, Bolton JL. Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones. Chemical Research in Toxicology. 14: 1643-53. PMID 11743747 DOI: 10.1021/Tx010137I  0.421
2001 Johnson BM, Bolton JL, Van Breemen RB. Screening botanical extracts for quinoid metabolites Chemical Research in Toxicology. 14: 1546-1551. PMID 11712913 DOI: 10.1021/tx010106n  0.324
2001 Hua Y, Wainhaus SB, Yang Y, Shen L, Xiong Y, Xu X, Zhang F, Bolton JL, van Breemen RB. Comparison of negative and positive ion electrospray tandem mass spectrometry for the liquid chromatography tandem mass spectrometry analysis of oxidized deoxynucleosides. Journal of the American Society For Mass Spectrometry. 12: 80-7. PMID 11142363 DOI: 10.1016/S1044-0305(00)00191-4  0.486
1999 Nikolic D, Fan PW, Bolton JL, van Breemen RB. Screening for xenobiotic electrophilic metabolites using pulsed ultrafiltration-mass spectrometry. Combinatorial Chemistry & High Throughput Screening. 2: 165-75. PMID 10420970  0.309
1998 van Breemen RB, Nikolic D, Xu X, Xiong Y, van Lieshout M, West CE, Schilling AB. Development of a method for quantitation of retinol and retinyl palmitate in human serum using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry. Journal of Chromatography. A. 794: 245-51. PMID 9491562 DOI: 10.1016/S0021-9673(97)01138-2  0.301
1993 Saljoughian M, Williams PG, Morimoto H, Goodlett DR, Van Breemen RB. Tritiated diimide: A regio- and stereo-selective tritium-labelling reagent Journal of the Chemical Society, Chemical Communications. 414-416. DOI: 10.1039/C39930000414  0.437
1990 Goodlett DR, Armstrong FB, Creech RJ, van Breemen RB. Formylated peptides from cyanogen bromide digests identified by fast atom bombardment mass spectrometry Analytical Biochemistry. 186: 116-120. PMID 2356963 DOI: 10.1016/0003-2697(90)90583-U  0.613
1988 Van Breemen RB, Stogniew M, Fenselau C. Characterization of acyl-linked glucuronides by electron impact and fast atom bombardment mass spectrometry Biomedical and Environmental Mass Spectrometry. 17: 97-103. PMID 3191255 DOI: 10.1002/bms.1200170205  0.433
1987 van Breemen RB, Fenselau CC, Cotter RJ, Curtis AJ, Connolly G. Derivatives of dicyclopentadiene in ground water. Biomedical & Environmental Mass Spectrometry. 14: 97-102. PMID 2953399 DOI: 10.1002/Bms.1200140302  0.526
1986 Van Breemen RB, Fenselau C, Mogilevsky W, Odell GB. Reaction of bilirubin glucuronides with serum albumin Journal of Chromatography B: Biomedical Sciences and Applications. 383: 387-392. PMID 3558567 DOI: 10.1016/S0378-4347(00)83484-2  0.376
1986 van Breemen RB, Fenselau CC, Dulik DM. Activated phase II metabolites: comparison of alkylation by 1-O-acyl glucuronides and acyl sulfates Advances in Experimental Medicine and Biology. 197: 423-429. PMID 3094339 DOI: 10.1007/978-1-4684-5134-4_41  0.44
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