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Lucio Miele - Publications

Molecular and Cellular Biochemistry Program Loyola University Chicago, Chicago, IL, United States 
Molecular Biology, Oncology

186 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Bao B, Wang Z, Ali S, Kong D, Li Y, Ahmad A, Banerjee S, Azmi AS, Miele L, Sarkar FH. Retraction notice to "Notch-1 induces Epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells". Cancer Letters. 423: 153. PMID 29606293 DOI: 10.1016/J.Canlet.2018.03.020  0.52
2016 Crabtree JS, Singleton CS, Miele L. Notch Signaling in Neuroendocrine Tumors. Frontiers in Oncology. 6: 94. PMID 27148486 DOI: 10.3389/fonc.2016.00094  0.68
2016 Hicks C, Sitthi-Amorn J, Douglas J, Ramani R, Miele L, Vijayakumar V, Karlson C, Chipeta J, Megason G. Molecular Analysis of Central Nervous System Disease Spectrum in Childhood Acute Lymphoblastic Leukemia. Clinical Medicine Insights. Oncology. 10: 5-15. PMID 26997880 DOI: 10.4137/CMO.S18180  0.68
2016 Su RW, Strug MR, Jeong JW, Miele L, Fazleabas AT. Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858409 DOI: 10.1073/pnas.1520441113  0.68
2015 Zhong Q, Zhang C, Zhang Q, Miele L, Zheng S, Wang G. Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status. Bmc Cancer. 15: 625. PMID 26354796 DOI: 10.1186/S12885-015-1621-2  0.68
2015 Pandya K, Wyatt D, Gallagher B, Bloodworth JC, Shah D, Baker A, Zlobin A, Pannuti A, Green AR, Ellis IO, Filipovic A, Sagert J, Rana A, Albain KS, Miele L, et al. PKCα Attenuates Jagged-1-mediated Notch Signaling in ErbB-2 positive Breast Cancer to Reverse Trastuzumab Resistance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26350262 DOI: 10.1158/1078-0432.CCR-15-0179  0.68
2015 Sorrentino C, Miele L, Porta A, Pinto A, Morello S. Myeloid-derived suppressor cells contribute to A2B adenosine receptor-induced VEGF production and angiogenesis in a mouse melanoma model. Oncotarget. 6: 27478-89. PMID 26317647 DOI: 10.18632/Oncotarget.4393  0.68
2015 Yun J, Espinoza I, Pannuti A, Romero D, Martinez L, Caskey M, Stanculescu A, Bocchetta M, Rizzo P, Band V, Band H, Kim HM, Park SK, Kang KW, Avantaggiati ML, ... ... Miele L, et al. p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating with the Notch Transcriptional Complex via MAML1. Journal of Cellular Physiology. PMID 26033683 DOI: 10.1002/Jcp.25052  0.68
2015 Takebe N, Miele L, Harris PJ, Jeong W, Bando H, Kahn M, Yang SX, Ivy SP. Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update. Nature Reviews. Clinical Oncology. PMID 25850553 DOI: 10.1038/nrclinonc.2015.61  0.68
2015 Zhang S, Chung WC, Wu G, Egan SE, Miele L, Xu K. Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction. Cancer Research. 75: 1936-43. PMID 25808869 DOI: 10.1158/0008-5472.CAN-14-3303  0.68
2015 Ramakrishnan G, Davaakhuu G, Chung WC, Zhu H, Rana A, Filipovic A, Green AR, Atfi A, Pannuti A, Miele L, Tzivion G. AKT and 14-3-3 regulate Notch4 nuclear localization. Scientific Reports. 5: 8782. PMID 25740432 DOI: 10.1038/Srep08782  0.68
2015 Nguyen D, Rubinstein L, Takebe N, Miele L, Tomaszewski JE, Ivy P, Doroshow JH, Yang SX. Notch1 phenotype and clinical stage progression in non-small cell lung cancer. Journal of Hematology & Oncology. 8: 9. PMID 25653136 DOI: 10.1186/s13045-014-0104-2  0.68
2015 Su RW, Strug MR, Joshi NR, Jeong JW, Miele L, Lessey BA, Young SL, Fazleabas AT. Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization. The Journal of Clinical Endocrinology and Metabolism. 100: E433-42. PMID 25546156 DOI: 10.1210/Jc.2014-3720  0.68
2014 Morello S, Miele L. Targeting the adenosine A2b receptor in the tumor microenvironment overcomes local immunosuppression by myeloid-derived suppressor cells. Oncoimmunology. 3: e27989. PMID 25101221 DOI: 10.4161/onci.27989  0.68
2014 Chinchar E, Makey KL, Gibson J, Chen F, Cole SA, Megason GC, Vijayakumar S, Miele L, Gu JW. Sunitinib significantly suppresses the proliferation, migration, apoptosis resistance, tumor angiogenesis and growth of triple-negative breast cancers but increases breast cancer stem cells. Vascular Cell. 6: 12. PMID 24914410 DOI: 10.1186/2045-824X-6-12  0.68
2014 Shin HM, Tilahun ME, Cho OH, Chandiran K, Kuksin CA, Keerthivasan S, Fauq AH, Golde TE, Miele L, Thome M, Osborne BA, Minter LM. NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome. Frontiers in Immunology. 5: 249. PMID 24904593 DOI: 10.3389/Fimmu.2014.00249  0.68
2014 De Salvo M, Raimondi L, Vella S, Adesso L, Ciarapica R, Verginelli F, Pannuti A, Citti A, Boldrini R, Milano GM, Cacchione A, Ferrari A, Collini P, Rosolen A, Bisogno G, ... ... Miele L, et al. Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells. Plos One. 9: e96238. PMID 24797362 DOI: 10.1371/Journal.Pone.0096238  0.68
2014 Antico G, Aloman M, Lakota K, Miele L, Fiore S, Sodin-Semrl S. Uteroglobin, a possible ligand of the lipoxin receptor inhibits serum amyloid A-driven inflammation. Mediators of Inflammation. 2014: 876395. PMID 24782597 DOI: 10.1155/2014/876395  0.68
2014 Dongre A, Surampudi L, Lawlor RG, Fauq AH, Miele L, Golde TE, Minter LM, Osborne BA. Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells. Frontiers in Immunology. 5: 54. PMID 24611064 DOI: 10.3389/Fimmu.2014.00054  0.68
2014 Zhang S, Chung WC, Miele L, Xu K. Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer. Cancer Biology & Therapy. 15: 633-42. PMID 24556651 DOI: 10.4161/cbt.28180  0.68
2014 Wells KJ, Lima DS, Meade CD, Muñoz-Antonia T, Scarinci I, McGuire A, Gwede CK, Pledger WJ, Partridge E, Lipscomb J, Matthews R, Matta J, Flores I, Weiner R, Turner T, ... Miele L, et al. Assessing needs and assets for building a regional network infrastructure to reduce cancer related health disparities. Evaluation and Program Planning. 44: 14-25. PMID 24486917 DOI: 10.1016/J.Evalprogplan.2013.12.003  0.68
2014 Ramakrishnan G, Davaakhuu G, Kaplun L, Chung WC, Rana A, Atfi A, Miele L, Tzivion G. Sirt2 deacetylase is a novel AKT binding partner critical for AKT activation by insulin. The Journal of Biological Chemistry. 289: 6054-66. PMID 24446434 DOI: 10.1074/jbc.M113.537266  0.68
2014 Bell D, Hanna EY, Miele L, Roberts D, Weber RS, El-Naggar AK. Expression and significance of notch signaling pathway in salivary adenoid cystic carcinoma. Annals of Diagnostic Pathology. 18: 10-3. PMID 24238845 DOI: 10.1016/j.anndiagpath.2013.10.001  0.68
2014 Tan Y, Qin S, Hou X, Qian X, Xia J, Li Y, Wang R, Chen C, Yang Q, Miele L, Wu Q, Wang Z. Proteomic-based analysis for identification of proteins involved in 5-fluorouracil resistance in hepatocellular carcinoma Current Pharmaceutical Design. 20: 81-87. PMID 23530500 DOI: 10.2174/138161282001140113125143  0.68
2014 Gao J, Sarkar FH, Miele L, Wang Z. The Role of Notch Signaling Pathway in the Progression of Pancreatic Cancer Molecular Diagnostics and Treatment of Pancreatic Cancer. 75-89. DOI: 10.1016/B978-0-12-408103-1.00004-2  0.68
2013 Iannone R, Miele L, Maiolino P, Pinto A, Morello S. Blockade of A2b adenosine receptor reduces tumor growth and immune suppression mediated by myeloid-derived suppressor cells in a mouse model of melanoma. Neoplasia (New York, N.Y.). 15: 1400-9. PMID 24403862 DOI: 10.1593/neo.131748  0.68
2013 Li Y, Ma J, Qian X, Wu Q, Xia J, Miele L, Sarkar FH, Wang Z. Regulation of EMT by Notch signaling pathway in tumor progression. Current Cancer Drug Targets. 13: 957-62. PMID 24168187 DOI: 10.2174/15680096113136660101  0.68
2013 Wu Q, Wang R, Yang Q, Hou X, Chen S, Hou Y, Chen C, Yang Y, Miele L, Sarkar FH, Chen Y, Wang Z. Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway. Oncotarget. 4: 1999-2009. PMID 24158561 DOI: 10.18632/oncotarget.1471  0.52
2013 Espinoza I, Pochampally R, Xing F, Watabe K, Miele L. Notch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transition. Oncotargets and Therapy. 6: 1249-59. PMID 24043949 DOI: 10.2147/Ott.S36162  0.68
2013 Hicks C, Miele L, Koganti T, Vijayakumar S. Comprehensive assessment and network analysis of the emerging genetic susceptibility landscape of prostate cancer. Cancer Informatics. 12: 175-91. PMID 24031161 DOI: 10.4137/CIN.S12128  0.68
2013 Ma J, Xia J, Miele L, Sarkar FH, Wang Z. Notch Signaling Pathway in Pancreatic Cancer Progression. Pancreatic Disorders & Therapy. 3. PMID 24027656  0.52
2013 Hicks C, Miele L, Koganti T, Young-Gaylor L, Rogers D, Vijayakumar V, Megason G. Analysis of Patterns of Gene Expression Variation within and between Ethnic Populations in Pediatric B-ALL. Cancer Informatics. 12: 155-73. PMID 24023509 DOI: 10.4137/CIN.S11831  0.68
2013 Cao Z, Bao M, Miele L, Sarkar FH, Wang Z, Zhou Q. Tumour vasculogenic mimicry is associated with poor prognosis of human cancer patients: a systemic review and meta-analysis. European Journal of Cancer (Oxford, England : 1990). 49: 3914-23. PMID 23992642 DOI: 10.1016/J.Ejca.2013.07.148  0.68
2013 Espinoza I, Miele L. Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells. Cancer Letters. 341: 41-5. PMID 23973264 DOI: 10.1016/j.canlet.2013.08.027  0.68
2013 Cao Z, Shang B, Zhang G, Miele L, Sarkar FH, Wang Z, Zhou Q. Tumor cell-mediated neovascularization and lymphangiogenesis contrive tumor progression and cancer metastasis. Biochimica Et Biophysica Acta. 1836: 273-86. PMID 23933263 DOI: 10.1016/J.Bbcan.2013.08.001  0.68
2013 Ma J, Zhang Q, Chen S, Fang B, Yang Q, Chen C, Miele L, Sarkar FH, Xia J, Wang Z. Mitochondrial dysfunction promotes breast cancer cell migration and invasion through HIF1α accumulation via increased production of reactive oxygen species. Plos One. 8: e69485. PMID 23922721 DOI: 10.1371/Journal.Pone.0069485  0.68
2013 Yun J, Pannuti A, Espinoza I, Zhu H, Hicks C, Zhu X, Caskey M, Rizzo P, D'Souza G, Backus K, Denning MF, Coon J, Sun M, Bresnick EH, Osipo C, ... ... Miele L, et al. Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells. Oncogenesis. 2: e60. PMID 23917222 DOI: 10.1038/oncsis.2013.26  0.68
2013 Zhu H, Zhou X, Redfield S, He Z, Lewin J, Miele L. Elevated expression of notch1 is associated with metastasis of human malignancies. International Journal of Surgical Pathology. 21: 449-54. PMID 23883974 DOI: 10.1177/1066896913496146  0.68
2013 Mo YY, Tang H, Miele L. Notch-associated microRNAs in cancer. Current Drug Targets. 14: 1157-66. PMID 23834150 DOI: 10.2174/13894501113149990188  0.68
2013 Ma J, Cheng L, Liu H, Zhang J, Shi Y, Zeng F, Miele L, Sarkar FH, Xia J, Wang Z. Genistein down-regulates miR-223 expression in pancreatic cancer cells Current Drug Targets. 14: 1150-1156. PMID 23834147 DOI: 10.2174/13894501113149990187  0.68
2013 Wang R, Ma J, Wu Q, Xia J, Miele L, Sarkar FH, Wang Z. Functional role of miR-34 family in human cancer Current Drug Targets. 14: 1185-1191. PMID 23834144 DOI: 10.2174/13894501113149990191  0.68
2013 Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L. γ-Secretase inhibitors and modulators. Biochimica Et Biophysica Acta. 1828: 2898-907. PMID 23791707 DOI: 10.1016/J.Bbamem.2013.06.005  0.68
2013 Hicks C, Koganti T, Brown AS, Monico J, Backus K, Miele L. Novel Integrative Genomics Approach for Associating GWAS Information with Intrinsic Subtypes of Breast Cancer. Cancer Informatics. 12: 125-42. PMID 23761956 DOI: 10.4137/CIN.S11452  0.68
2013 Roderick JE, Gonzalez-Perez G, Kuksin CA, Dongre A, Roberts ER, Srinivasan J, Andrzejewski C, Fauq AH, Golde TE, Miele L, Minter LM. Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia. The Journal of Experimental Medicine. 210: 1311-29. PMID 23733784 DOI: 10.1084/Jem.20112615  0.68
2013 Zhu H, Zhou X, Redfield S, Lewin J, Miele L. Elevated Jagged-1 and Notch-1 expression in high grade and metastatic prostate cancers. American Journal of Translational Research. 5: 368-78. PMID 23634247  0.68
2013 Gopisetty A, Bhattacharya P, Haddad C, Bruno JC, Vasu C, Miele L, Prabhakar BS. OX40L/Jagged1 cosignaling by GM-CSF-induced bone marrow-derived dendritic cells is required for the expansion of functional regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 5516-25. PMID 23630352 DOI: 10.4049/Jimmunol.1202298  0.68
2013 Zhang G, Yang P, Guo P, Miele L, Sarkar FH, Wang Z, Zhou Q. Unraveling the mystery of cancer metabolism in the genesis of tumor-initiating cells and development of cancer. Biochimica Et Biophysica Acta. 1836: 49-59. PMID 23523716 DOI: 10.1016/J.Bbcan.2013.03.001  0.68
2013 Espinoza I, Miele L. Notch inhibitors for cancer treatment. Pharmacology & Therapeutics. 139: 95-110. PMID 23458608 DOI: 10.1016/J.Pharmthera.2013.02.003  0.68
2013 Hicks C, Kumar R, Pannuti A, Backus K, Brown A, Monico J, Miele L. An Integrative Genomics Approach for Associating GWAS Information with Triple-Negative Breast Cancer. Cancer Informatics. 12: 1-20. PMID 23423317 DOI: 10.4137/Cin.S10413  0.68
2013 Wu Q, Hou X, Xia J, Qian X, Miele L, Sarkar FH, Wang Z. Emerging roles of PDGF-D in EMT progression during tumorigenesis Cancer Treatment Reviews. 39: 640-646. PMID 23261166 DOI: 10.1016/J.Ctrv.2012.11.006  0.68
2013 Tan Y, Wu Q, Xia J, Miele L, Sarkar FH, Wang Z. Systems biology approaches in identifying the targets of natural compounds for cancer therapy Current Drug Discovery Technologies. 10: 139-146. PMID 23237676 DOI: 10.2174/1570163811310020006  0.68
2013 Rizzo P, Miele L, Ferrari R. The Notch pathway: a crossroad between the life and death of the endothelium. European Heart Journal. 34: 2504-9. PMID 22645188 DOI: 10.1093/eurheartj/ehs141  0.68
2013 Espinoza I, Miele L. Development of notch pathway inhibitors for cancer therapy Breast Cancer Metastasis and Drug Resistance: Progress and Prospects. 2147483647: 291-327. DOI: 10.1007/978-1-4614-5647-6_17  0.68
2012 Tan Y, Miele L, Sarkar FH, Wang Z. Identifying Biomarkers and Drug Targets Using Systems Biology Approaches for Pancreatic Cancer. Pancreatic Disorders & Therapy. 2: 1000e128. PMID 23378937  0.52
2012 Rota R, Ciarapica R, Miele L, Locatelli F. Notch signaling in pediatric soft tissue sarcomas. Bmc Medicine. 10: 141. PMID 23158439 DOI: 10.1186/1741-7015-10-141  0.68
2012 Wu Q, Miele L, Sarkar FH, Wang Z. The Role of EMT in Pancreatic Cancer Progression. Pancreatic Disorders & Therapy. 2. PMID 23145368 DOI: 10.4172/2165-7092.1000e121  0.52
2012 Xia J, Duan Q, Ahmad A, Bao B, Banerjee S, Shi Y, Ma J, Geng J, Chen Z, Rahman KM, Miele L, Sarkar FH, Wang Z. Genistein inhibits cell growth and induces apoptosis through up-regulation of miR-34a in pancreatic cancer cells. Current Drug Targets. 13: 1750-6. PMID 23140286 DOI: 10.2174/138945012804545597  0.52
2012 Xia J, Li Y, Yang Q, Mei C, Chen Z, Bao B, Ahmad A, Miele L, Sarkar FH, Wang Z. Arsenic trioxide inhibits cell growth and induces apoptosis through inactivation of notch signaling pathway in breast cancer. International Journal of Molecular Sciences. 13: 9627-41. PMID 22949821 DOI: 10.3390/Ijms13089627  0.52
2012 Xia J, Chen C, Chen Z, Miele L, Sarkar FH, Wang Z. Targeting pancreatic cancer stem cells for cancer therapy. Biochimica Et Biophysica Acta. 1826: 385-99. PMID 22728049 DOI: 10.1016/J.Bbcan.2012.06.002  0.68
2012 Pallavi SK, Ho DM, Hicks C, Miele L, Artavanis-Tsakonas S. Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila. The Embo Journal. 31: 2895-907. PMID 22580825 DOI: 10.1038/emboj.2012.129  0.68
2012 Afshar Y, Miele L, Fazleabas AT. Notch1 is regulated by chorionic gonadotropin and progesterone in endometrial stromal cells and modulates decidualization in primates. Endocrinology. 153: 2884-96. PMID 22535768 DOI: 10.1210/En.2011-2122  0.68
2012 Gu JW, Rizzo P, Pannuti A, Golde T, Osborne B, Miele L. Notch signals in the endothelium and cancer "stem-like" cells: opportunities for cancer therapy. Vascular Cell. 4: 7. PMID 22487493 DOI: 10.1186/2045-824X-4-7  0.68
2012 Hicks C, Kumar R, Pannuti A, Miele L. Integrative Analysis of Response to Tamoxifen Treatment in ER-Positive Breast Cancer Using GWAS Information and Transcription Profiling. Breast Cancer : Basic and Clinical Research. 6: 47-66. PMID 22399860 DOI: 10.4137/BCBCR.S8652  0.68
2012 Raimondi L, Ciarapica R, De Salvo M, Verginelli F, Gueguen M, Martini C, De Sio L, Cortese G, Locatelli M, Dang TP, Carlesso N, Miele L, Stifani S, Limon I, Locatelli F, et al. Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21(Cip1) expression and hampers tumour cell growth in vitro and in vivo. Cell Death and Differentiation. 19: 871-81. PMID 22117196 DOI: 10.1038/Cdd.2011.171  0.68
2012 Afshar Y, Jeong JW, Roqueiro D, DeMayo F, Lydon J, Radtke F, Radnor R, Miele L, Fazleabas A. Notch1 mediates uterine stromal differentiation and is critical for complete decidualization in the mouse. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 282-94. PMID 21990372 DOI: 10.1096/Fj.11-184663  0.68
2011 Cho S, Lu M, He X, Ee PL, Bhat U, Schneider E, Miele L, Beck WT. Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 20778-83. PMID 22143792 DOI: 10.1073/Pnas.1019452108  0.68
2011 Rota R, Ciarapica R, Giordano A, Miele L, Locatelli F. MicroRNAs in rhabdomyosarcoma: pathogenetic implications and translational potentiality. Molecular Cancer. 10: 120. PMID 21943149 DOI: 10.1186/1476-4598-10-120  0.68
2011 Selever J, Gu G, Lewis MT, Beyer A, Herynk MH, Covington KR, Tsimelzon A, Dontu G, Provost P, Di Pietro A, Boumendjel A, Albain K, Miele L, Weiss H, Barone I, et al. Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 6510-21. PMID 21878538 DOI: 10.1158/1078-0432.Ccr-11-1403  0.68
2011 Miele L. Transcription factor RBPJ/CSL: a genome-wide look at transcriptional regulation. Proceedings of the National Academy of Sciences of the United States of America. 108: 14715-6. PMID 21873209 DOI: 10.1073/pnas.1110570108  0.68
2011 Hicks C, Asfour R, Pannuti A, Miele L. An integrative genomics approach to biomarker discovery in breast cancer. Cancer Informatics. 10: 185-204. PMID 21869864 DOI: 10.4137/CIN.S6837  0.68
2011 Pandya K, Meeke K, Clementz AG, Rogowski A, Roberts J, Miele L, Albain KS, Osipo C. Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence. British Journal of Cancer. 105: 796-806. PMID 21847123 DOI: 10.1038/Bjc.2011.321  0.68
2011 Keerthivasan S, Suleiman R, Lawlor R, Roderick J, Bates T, Minter L, Anguita J, Juncadella I, Nickoloff BJ, Le Poole IC, Miele L, Osborne BA. Notch signaling regulates mouse and human Th17 differentiation. Journal of Immunology (Baltimore, Md. : 1950). 187: 692-701. PMID 21685328 DOI: 10.4049/Jimmunol.1003658  0.68
2011 Clementz AG, Rogowski A, Pandya K, Miele L, Osipo C. NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications. Breast Cancer Research : Bcr. 13: R63. PMID 21679465 DOI: 10.1186/Bcr2900  0.68
2011 Wang Z, Banerjee S, Ahmad A, Li Y, Azmi AS, Gunn JR, Kong D, Bao B, Ali S, Gao J, Mohammad RM, Miele L, Korc M, Sarkar FH. Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways. Plos One. 6: e20537. PMID 21673986 DOI: 10.1371/Journal.Pone.0020537  0.52
2011 Ciarapica R, Miele L, Giordano A, Locatelli F, Rota R. Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications. Bmc Medicine. 9: 63. PMID 21609503 DOI: 10.1186/1741-7015-9-63  0.68
2011 Hicks C, Pannuti A, Miele L. Associating GWAS Information with the Notch Signaling Pathway Using Transcription Profiling. Cancer Informatics. 10: 93-108. PMID 21584266 DOI: 10.4137/CIN.S6072  0.68
2011 Wang Z, Ahmad A, Li Y, Azmi AS, Miele L, Sarkar FH. Targeting notch to eradicate pancreatic cancer stem cells for cancer therapy. Anticancer Research. 31: 1105-13. PMID 21508353  0.68
2011 Bao B, Wang Z, Ali S, Kong D, Banerjee S, Ahmad A, Li Y, Azmi AS, Miele L, Sarkar FH. Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. Journal of Cellular Biochemistry. 112: 2296-306. PMID 21503965 DOI: 10.1002/Jcb.23150  0.52
2011 Bao B, Wang Z, Ali S, Kong D, Li Y, Ahmad A, Banerjee S, Azmi AS, Miele L, Sarkar FH. Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Letters. 307: 26-36. PMID 21463919 DOI: 10.1016/J.Canlet.2011.03.012  0.52
2011 Gu JW, Young E, Patterson SG, Makey KL, Wells J, Huang M, Tucker KB, Miele L. Postmenopausal obesity promotes tumor angiogenesis and breast cancer progression in mice. Cancer Biology & Therapy. 11: 910-7. PMID 21451264 DOI: 10.4161/cbt.11.10.15473  0.68
2011 Bell D, Miele L. A magnifying glass on glioblastoma stem cell signaling pathways. Cancer Biology & Therapy. 11: 765-8. PMID 21386658 DOI: 10.4161/Cbt.11.8.15277  0.68
2011 Liao S, Xia J, Chen Z, Zhang S, Ahmad A, Miele L, Sarkar FH, Wang Z. Inhibitory effect of curcumin on oral carcinoma CAL-27 cells via suppression of Notch-1 and NF-κB signaling pathways. Journal of Cellular Biochemistry. 112: 1055-65. PMID 21308734 DOI: 10.1002/Jcb.23019  0.52
2011 Wang Z, Li Y, Ahmad A, Banerjee S, Azmi AS, Kong D, Wojewoda C, Miele L, Sarkar FH. Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells. Journal of Cellular Biochemistry. 112: 78-88. PMID 20658545 DOI: 10.1002/Jcb.22770  0.52
2011 Yao K, Rizzo P, Rajan P, Albain K, Rychlik K, Shah S, Miele L. Notch-1 and notch-4 receptors as prognostic markers in breast cancer. International Journal of Surgical Pathology. 19: 607-13. PMID 20444726 DOI: 10.1177/1066896910362080  0.68
2011 Miele L. Transcription factor RBPJ/CSL: A genome-wide look at transcriptional regulation (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 36, (14715-14716) DOI: 10.1073/pnas.1110570108) Proceedings of the National Academy of Sciences of the United States of America. 108: 16481. DOI: 10.1073/pnas.1114338108  0.68
2010 Grudzien P, Lo S, Albain KS, Robinson P, Rajan P, Strack PR, Golde TE, Miele L, Foreman KE. Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation. Anticancer Research. 30: 3853-67. PMID 21036696  0.68
2010 Young E, Miele L, Tucker KB, Huang M, Wells J, Gu JW. SU11248, a selective tyrosine kinases inhibitor suppresses breast tumor angiogenesis and growth via targeting both tumor vasculature and breast cancer cells. Cancer Biology & Therapy. 10: 703-11. PMID 20686367 DOI: 10.4161/cbt.10.7.12904  0.68
2010 Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, Osborne B, Miele L. Targeting Notch to target cancer stem cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3141-52. PMID 20530696 DOI: 10.1158/1078-0432.Ccr-09-2823  0.68
2010 Dumortier A, Durham AD, Di Piazza M, Vauclair S, Koch U, Ferrand G, Ferrero I, Demehri S, Song LL, Farr AG, Leonard WJ, Kopan R, Miele L, Hohl D, Finke D, et al. Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin. Plos One. 5: e9258. PMID 20174635 DOI: 10.1371/Journal.Pone.0009258  0.68
2010 Eliasz S, Liang S, Chen Y, De Marco MA, Machek O, Skucha S, Miele L, Bocchetta M. Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway. Oncogene. 29: 2488-98. PMID 20154720 DOI: 10.1038/Onc.2010.7  0.68
2010 Hao L, Rizzo P, Osipo C, Pannuti A, Wyatt D, Cheung LW, Sonenshein G, Osborne BA, Miele L. Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells. Oncogene. 29: 201-13. PMID 19838210 DOI: 10.1038/Onc.2009.323  0.68
2009 Rizzo P, Osipo C, Pannuti A, Golde T, Osborne B, Miele L. Targeting Notch signaling cross-talk with estrogen receptor and ErbB-2 in breast cancer. Advances in Enzyme Regulation. 49: 134-41. PMID 19344631 DOI: 10.1016/J.Advenzreg.2009.01.008  0.68
2009 Cho OH, Shin HM, Miele L, Golde TE, Fauq A, Minter LM, Osborne BA. Notch regulates cytolytic effector function in CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 3380-9. PMID 19265115 DOI: 10.4049/Jimmunol.0802598  0.68
2008 Graziani I, Eliasz S, De Marco MA, Chen Y, Pass HI, De May RM, Strack PR, Miele L, Bocchetta M. Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway. Cancer Research. 68: 9678-85. PMID 19047145 DOI: 10.1158/0008-5472.Can-08-0969  0.68
2008 Rizzo P, Osipo C, Foreman K, Golde T, Osborne B, Miele L. Rational targeting of Notch signaling in cancer. Oncogene. 27: 5124-31. PMID 18758481 DOI: 10.1038/Onc.2008.226  0.68
2008 Miele L. Rational targeting of Notch signaling in breast cancer. Expert Review of Anticancer Therapy. 8: 1197-202. PMID 18699758 DOI: 10.1586/14737140.8.8.1197  0.68
2008 Rizzo P, Miao H, D'Souza G, Osipo C, Song LL, Yun J, Zhao H, Mascarenhas J, Wyatt D, Antico G, Hao L, Yao K, Rajan P, Hicks C, Siziopikou K, ... ... Miele L, et al. Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Research. 68: 5226-35. PMID 18593923 DOI: 10.1158/0008-5472.Can-07-5744  0.68
2008 Samon JB, Champhekar A, Minter LM, Telfer JC, Miele L, Fauq A, Das P, Golde TE, Osborne BA. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood. 112: 1813-21. PMID 18550850 DOI: 10.1182/Blood-2008-03-144980  0.68
2008 Osipo C, Patel P, Rizzo P, Clementz AG, Hao L, Golde TE, Miele L. ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor. Oncogene. 27: 5019-32. PMID 18469855 DOI: 10.1038/Onc.2008.149  0.68
2008 Osipo C, Golde TE, Osborne BA, Miele LA. Off the beaten pathway: the complex cross talk between Notch and NF-kappaB. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 11-7. PMID 18059366 DOI: 10.1038/Labinvest.3700700  0.68
2008 Rizzo P, Miao H, D'Souza G, Osipo C, Song LL, Yun J, Zhao H, Mascarenhas J, Wyatt D, Antico G, Hao L, Yao K, Rajan P, Hicks C, Siziopikou K, ... ... Miele L, et al. Cross-talk between Notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches (Cancer Research (July 1, 2008) 68 (5226-5235)) Cancer Research. 68: 7246. DOI: 10.1158/0008-5472.Can-68-17-Cor1  0.68
2007 Chen Y, De Marco MA, Graziani I, Gazdar AF, Strack PR, Miele L, Bocchetta M. Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung. Cancer Research. 67: 7954-9. PMID 17804701 DOI: 10.1158/0008-5472.Can-07-1229  0.68
2007 Afshar Y, Stanculescu A, Miele L, Fazleabas AT. The role of chorionic gonadotropin and Notch1 in implantation. Journal of Assisted Reproduction and Genetics. 24: 296-302. PMID 17616802 DOI: 10.1007/S10815-007-9149-2  0.68
2007 Curry CL, Reed LL, Broude E, Golde TE, Miele L, Foreman KE. Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-kappaB signaling. Molecular Cancer Therapeutics. 6: 1983-92. PMID 17604336 DOI: 10.1158/1535-7163.Mct-07-0093  0.68
2007 Song LL, Miele L. Cancer stem cells--an old idea that's new again: implications for the diagnosis and treatment of breast cancer. Expert Opinion On Biological Therapy. 7: 431-8. PMID 17373895 DOI: 10.1517/14712598.7.4.431  0.68
2007 Kanamori M, Kawaguchi T, Nigro JM, Feuerstein BG, Berger MS, Miele L, Pieper RO. Contribution of Notch signaling activation to human glioblastoma multiforme. Journal of Neurosurgery. 106: 417-27. PMID 17367064 DOI: 10.3171/Jns.2007.106.3.417  0.68
2007 De Falco M, Cobellis L, Giraldi D, Mastrogiacomo A, Perna A, Colacurci N, Miele L, De Luca A. Expression and Distribution of Notch Protein Members in Human Placenta Throughout Pregnancy Placenta. 28: 118-126. PMID 17185135 DOI: 10.1016/j.placenta.2006.03.010  0.68
2006 Miele L, Golde T, Osborne B. Notch signaling in cancer. Current Molecular Medicine. 6: 905-18. PMID 17168741 DOI: 10.2174/156652406779010830  0.68
2006 Miele L, Miao H, Nickoloff BJ. NOTCH signaling as a novel cancer therapeutic target. Current Cancer Drug Targets. 6: 313-23. PMID 16848722 DOI: 10.2174/156800906777441771  0.68
2006 Curry CL, Reed LL, Nickoloff BJ, Miele L, Foreman KE. Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 842-52. PMID 16732296 DOI: 10.1038/Labinvest.3700442  0.68
2006 Arumugam TV, Chan SL, Jo DG, Yilmaz G, Tang SC, Cheng A, Gleichmann M, Okun E, Dixit VD, Chigurupati S, Mughal MR, Ouyang X, Miele L, Magnus T, Poosala S, et al. Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke. Nature Medicine. 12: 621-3. PMID 16680150 DOI: 10.1038/Nm1403  0.68
2006 Osipo C, Miele L. Hedgehog signaling in hepatocellular carcinoma: novel therapeutic strategy targeting hedgehog signaling in HCC. Cancer Biology & Therapy. 5: 238-9. PMID 16552173 DOI: 10.4161/Cbt.5.2.2566  0.68
2006 Antico G, Lingen MW, Sassano A, Melby J, Welch RW, Fiore S, Pilon AL, Miele L. Recombinant human uteroglobin/CC10 inhibits the adhesion and migration of primary human endothelial cells via specific and saturable binding to fibronectin. Journal of Cellular Physiology. 207: 553-61. PMID 16453303 DOI: 10.1002/Jcp.20604  0.68
2005 Nickoloff BJ, Hendrix MJ, Pollock PM, Trent JM, Miele L, Qin JZ. Notch and NOXA-related pathways in melanoma cells. The Journal of Investigative Dermatology. Symposium Proceedings / the Society For Investigative Dermatology, Inc. [and] European Society For Dermatological Research. 10: 95-104. PMID 16363061 DOI: 10.1111/j.1087-0024.2005.200404.x  0.68
2005 Minter LM, Turley DM, Das P, Shin HM, Joshi I, Lawlor RG, Cho OH, Palaga T, Gottipati S, Telfer JC, Kostura L, Fauq AH, Simpson K, Such KA, Miele L, et al. Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nature Immunology. 6: 680-8. PMID 15991363 DOI: 10.1038/Ni1209X  0.68
2005 Curry CL, Reed LL, Golde TE, Miele L, Nickoloff BJ, Foreman KE. Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells. Oncogene. 24: 6333-44. PMID 15940249 DOI: 10.1038/Sj.Onc.1208783  0.68
2005 Song L, Zlobin A, Ghoshal P, Zhang Q, Houde C, Weijzen S, Jiang Q, Nacheva E, Yagan D, Davis E, Galiegue-Zouitina S, Catovsky D, Grogan T, Fisher RI, Miele L, et al. Alteration of SMRT tumor suppressor function in transformed non-Hodgkin lymphomas. Cancer Research. 65: 4554-61. PMID 15930272 DOI: 10.1158/0008-5472.Can-04-4108  0.68
2005 Song LL, Miele L. Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells Women's Oncology Review. 5: 9-11. DOI: 10.3109/14733400500089633  0.68
2005 Rizzo P, Miele L. Evidence for the Notch signaling pathway on the role of estrogen in angiogenesis Women's Oncology Review. 5: 13-16. DOI: 10.1080/14733400500089617  0.68
2004 Miele L. The biology of cyclins and cyclin-dependent protein kinases: an introduction Methods in Molecular Biology (Clifton, N.J.). 285: 3-21. PMID 15269391  0.68
2004 Wang Y, Chan SL, Miele L, Yao PJ, Mackes J, Ingram DK, Mattson MP, Furukawa K. Involvement of Notch signaling in hippocampal synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. 101: 9458-62. PMID 15190179 DOI: 10.1073/Pnas.0308126101  0.68
2003 Nickoloff BJ, Osborne BA, Miele L. Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents. Oncogene. 22: 6598-608. PMID 14528285 DOI: 10.1038/Sj.Onc.1206758  0.68
2003 Palaga T, Miele L, Golde TE, Osborne BA. TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 3019-24. PMID 12960327 DOI: 10.4049/Jimmunol.171.6.3019  0.68
2003 Carbone M, Pass HI, Miele L, Bocchetta M. New developments about the association of SV40 with human mesothelioma Oncogene. 22: 5173-5180. PMID 12910254 DOI: 10.1038/Sj.Onc.1206552  0.68
2003 Cheng P, Nefedova Y, Miele L, Osborne BA, Gabrilovich D. Notch signaling is necessary but not sufficient for differentiation of dendritic cells. Blood. 102: 3980-8. PMID 12907456 DOI: 10.1182/Blood-2003-04-1034  0.68
2003 Carbone M, Bocchetta M, Cristaudo A, Emri S, Gazdar A, Jasani B, Lednicky J, Miele L, Mutti L, Pass HI, Ramael M, Rizzo P, Testa JR, Weggen S, Yeung A. SV40 and human brain tumors. International Journal of Cancer. Journal International Du Cancer. 106: 140-2; author reply . PMID 12794770 DOI: 10.1002/Ijc.11189  0.68
2003 Weijzen S, Zlobin A, Braid M, Miele L, Kast WM. HPV16 E6 and E7 oncoproteins regulate Notch-1 expression and cooperate to induce transformation. Journal of Cellular Physiology. 194: 356-62. PMID 12548555 DOI: 10.1002/Jcp.10217  0.68
2003 Bocchetta M, Miele L, Pass HI, Carbone M. Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells. Oncogene. 22: 81-9. PMID 12527910 DOI: 10.1038/Sj.Onc.1206097  0.68
2003 Miele L. New weapons against inflammation: Dual inhibitors of phospholipase A2 and transglutaminase Journal of Clinical Investigation. 111: 19-21. PMID 12511581 DOI: 10.1172/JCI200317506  0.68
2003 Miele L. Apoptosis and antiapoptosis in multimodality cancer treatment Cancer Immunology, Immunotherapy. 52.  0.68
2003 Miele L. Session IV: Discussion session: Regulatory perspectives, including FDA - Developing cancer immunotherapies for the clinic: Regulatory perspectives Cancer Immunology, Immunotherapy. 52.  0.68
2002 Weijzen S, Velders MP, Elmishad AG, Bacon PE, Panella JR, Nickoloff BJ, Miele L, Kast WM. The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 4273-8. PMID 12370358 DOI: 10.4049/Jimmunol.169.8.4273  0.68
2002 Weijzen S, Rizzo P, Braid M, Vaishnav R, Jonkheer SM, Zlobin A, Osborne BA, Gottipati S, Aster JC, Hahn WC, Rudolf M, Siziopikou K, Kast WM, Miele L. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nature Medicine. 8: 979-86. PMID 12185362 DOI: 10.1038/Nm754  0.68
2002 Chowdhury B, Mantile-Selvaggi G, Miele L, Cordella-Miele E, Zhang Z, Mukherjee AB. Lys 43 and Asp 46 in alpha-helix 3 of uteroglobin are essential for its phospholipase A2 inhibitory activity. Biochemical and Biophysical Research Communications. 295: 877-83. PMID 12127976 DOI: 10.1016/S0006-291X(02)00767-2  0.68
2002 Nickoloff BJ, Qin JZ, Chaturvedi V, Denning MF, Bonish B, Miele L. Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-κB and PPARγ Cell Death and Differentiation. 9: 842-855. PMID 12107827 DOI: 10.1038/Sj.Cdd.4401036  0.68
2001 Cheng P, Zlobin A, Volgina V, Gottipati S, Osborne B, Simel EJ, Miele L, Gabrilovichz DI. Notch-1 regulates NF-κB activity in hemopoietic progenitor cells Journal of Immunology. 167: 4458-4467. PMID 11591772 DOI: 10.4049/Jimmunol.167.8.4458  0.68
2001 Wang J, Shelly L, Miele L, Boykins R, Norcross MA, Guan E. Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain. Journal of Immunology (Baltimore, Md. : 1950). 167: 289-95. PMID 11418662  0.68
2000 Zlobin A, Jang M, Miele L. Toward the rational design of cell fate modifiers: notch signaling as a target for novel biopharmaceuticals Current Pharmaceutical Biotechnology. 1: 83-106. PMID 11467364  0.68
2000 Jang MS, Zlobin A, Kast WM, Miele L. Notch signaling as a target in multimodality cancer therapy Current Opinion in Molecular Therapeutics. 2: 55-65. PMID 11249652  0.68
2000 Chowdhury B, Mantile-Selvaggi G, Kundu GC, Miele L, Cordella-Miele E, Zhang Z, Mukherjee AB. Amino acid residues in alpha-helix-3 of human uteroglobin are critical for its phospholipase A2 inhibitory activity. Annals of the New York Academy of Sciences. 923: 307-11. PMID 11193767 DOI: 10.1111/j.1749-6632.2000.tb05539.x  0.68
2000 Miele L. Bioactive peptides derived from uteroglobin Annals of the New York Academy of Sciences. 923: 128-140. PMID 11193751 DOI: 10.1111/J.1749-6632.2000.Tb05524.X  0.68
2000 Pattabiraman N, Matthews JH, Ward KB, Mantile-Selvaggi G, Miele L, Mukherjee AB. Crystal structure analysis of recombinant human uteroglobin and molecular modeling of ligand binding Annals of the New York Academy of Sciences. 923: 113-127. PMID 11193750  0.68
2000 Peri A, Bonaccorsi L, Muratori M, Luconi M, Baldi E, Granchi S, Pesciullesi A, Mini E, Cioppi F, Forti G, Serio M, Miele L, Maggi M. Uteroglobin reverts the transformed phenotype in the endometrial adenocarcinoma cell line HEC-1A by disrupting the metabolic pathways generating platelet-activating factor International Journal of Cancer. 88: 525-534. PMID 11058867 DOI: 10.1002/1097-0215(20001115)88:4<525::Aid-Ijc3>3.0.Co;2-Z  0.68
2000 Yasutomo K, Doyle C, Miele L, Germain RN. The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate Nature. 404: 506-510. PMID 10761920 DOI: 10.1038/35006664  0.68
2000 Mantile G, Fuchs C, Cordella-Miele E, Peri A, Mukherjee AB, Miele L. Stable, long-term bacterial production of soluble, dimeric, disulfide-bonded protein pharmaceuticals without antibiotic selection Biotechnology Progress. 16: 17-25. PMID 10662484 DOI: 10.1021/bp990129g  0.68
1999 Osborne B, Miele L. Notch and the immune system Immunity. 11: 653-663. PMID 10626888 DOI: 10.1016/S1074-7613(00)80140-5  0.68
1999 Miele L, Osborne B. Arbiter of differentiation and death: Notch signaling meets apoptosis Journal of Cellular Physiology. 181: 393-409. PMID 10528225 DOI: 10.1002/(Sici)1097-4652(199912)181:3<393::Aid-Jcp3>3.0.Co;2-6  0.68
1999 Shelly LL, Fuchs C, Miele L. Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds Journal of Cellular Biochemistry. 73: 164-175. PMID 10227380 DOI: 10.1002/(SICI)1097-4644(19990501)73:2<164::AID-JCB3>3.0.CO;2-0  0.68
1997 Miele L. Cystic fibrosis gene mutation (ΔF508) is associated with an intrinsic abnormality in Ca2+-induced arachidonic acid release by epithelial cells Dna and Cell Biology. 16: 749-759. PMID 9212168 DOI: 10.1089/dna.1997.16.749  0.68
1997 Miele L, Stein KE. Points to consider in the manufacture and testing of monoclonal antibody products for human use (1997) Journal of Immunotherapy. 20: 214-243. PMID 9181460 DOI: 10.1097/00002371-199705000-00007  0.68
1997 Carlomagno T, Mantile G, Bazzo R, Miele L, Paolillo L, Mukherjee AB, Barbato G. Resonance assignment and secondary structure determination and stability of the recombinant human uteroglobin with heteronuclear multidimensional NMR Journal of Biomolecular Nmr. 9: 35-46. PMID 9081543 DOI: 10.1023/A:1018619501038  0.68
1997 Miele L. Plants as bioreactors for biopharmaceuticals: Regulatory considerations Trends in Biotechnology. 15: 45-50. PMID 9081298 DOI: 10.1016/S0167-7799(97)84202-3  0.68
1996 Kundu GC, Mantile G, Miele L, Cordella-Miele E, Mukherjee AB. Recombinant human uteroglobin suppresses cellular invasiveness via a novel class of high-affinity cell surface binding site Proceedings of the National Academy of Sciences of the United States of America. 93: 2915-2919. PMID 8610142 DOI: 10.1073/pnas.93.7.2915  0.68
1995 Xing M, Miele L, Mukherjee AB. Arachidonic acid release from NIH 3T3 cells by group-I phospholipase A2: Involvement of a receptor-mediated mechanism Journal of Cellular Physiology. 165: 566-575. PMID 7593236 DOI: 10.1002/jcp.1041650315  0.68
1994 Mukherjee AB, Miele L, Pattabiraman N. Phospholipase A2 enzymes: Regulation and physiological role Biochemical Pharmacology. 48: 1-10. PMID 8043009 DOI: 10.1016/0006-2952(94)90216-X  0.68
1994 Leyton J, Manyak MJ, Patierno SR, Mukherjee AB, Miele L, Mantile G. Recombinant Human Uteroglobin Inhibits the in Vitro Invasiveness of Human Metastatic Prostate Tumor Cells and the Release of Arachidonic Acid Stimulated by Fibroblast-conditioned Medium1 Cancer Research. 54: 3696-3699. PMID 8033085  0.68
1994 Chock SP, Schmauder-Chock EA, Cordella-Miele E, Miele L, Mukherjee AB. The localization of phospholipase A2 in the secretory granule Biochemical Journal. 300: 619-622. PMID 8010941  0.68
1994 Miele L, Peri A, Cordella-Miele E, Mukherjee AB. Development of novel, sensitive, nonradioactive, quantitative ELISA-PCR methods potentially applicable to the detection of fetal cells in maternal circulation Annals of the New York Academy of Sciences. 731: 246-247. PMID 7944128 DOI: 10.1111/j.1749-6632.1994.tb55777.x  0.68
1994 Miele L, Cordella-Miele E, Mantile G, Peri A, Mukherjee AB. Uteroglobin and uteroglobin-like proteins: The uteroglobin family of proteins Journal of Endocrinological Investigation. 17: 679-692. PMID 7868811 DOI: 10.1007/BF03349687  0.68
1994 Matthews JH, Pattabiraman N, Ward KB, Mantile G, Miele L, Mukherjee AB. Crystallization and characterization of the recombinant human Clara cell 10-kDa protein Proteins: Structure, Function and Genetics. 20: 191-196. PMID 7846028 DOI: 10.1002/Prot.340200209  0.68
1994 Ulane MM, Butler JD, Peri A, Miele L, Ulane RE, Hubbard VS. Cystic fibrosis and phosphatidylcholine biosynthesis. Clinica Chimica Acta; International Journal of Clinical Chemistry. 230: 109-16. PMID 7834862 DOI: 10.1016/0009-8981(94)90263-1  0.68
1994 Miele L, Peri A, Cordella-Miele E, Mukherjee AB. Nonradiometric ELISA-based quantitation and validation of polymerase chain reaction-amplified DNA, including detection of point mutations, without allele-specific amplification, or ligation Dna and Cell Biology. 13: 1233-1242. PMID 7529025  0.68
1994 Peri A, Cowan BD, Bhartiya D, Miele L, Nieman LK, Nwaeze IO, Mukherjee AB. Expression of Clara cell 10-kD gene in the human endometrium and its relationship to ovarian menstrual cycle Dna and Cell Biology. 13: 495-503. PMID 7517678 DOI: 10.1089/Dna.1994.13.495  0.68
1993 Butler JD, Levin SW, Facchiano A, Miele L, Mukherjee AB. Amino acid composition and N-terminal sequence of purified cystine binding protein of Escherichia coli. Life Sciences. 52: 1209-15. PMID 8450713 DOI: 10.1016/0024-3205(93)90103-A  0.68
1993 Peri A, Cordella-Miele E, Miele L, Mukherjee AB. Tissue-specific expression of the gene coding for human clara cell 10-kD protein, a phospholipase A2-inhibitory protein Journal of Clinical Investigation. 92: 2099-2109. PMID 8227325 DOI: 10.1172/Jci116810  0.68
1993 Mantile G, Miele L, Cordella-Miele E, Singh G, Katyal SL, Mukherjee AB. Human Clara cell 10-kDa protein is the counterpart of rabbit uteroglobin. The Journal of Biological Chemistry. 268: 20343-51. PMID 8104186  0.68
1993 Cordella-miele E, Miele L, Beninati S, Mukherjee AB. Transglutaminase-catalyzed incorporation of polyamines into phospholipase A2 Journal of Biochemistry. 113: 164-173. PMID 8096844 DOI: 10.1093/Oxfordjournals.Jbchem.A124021  0.68
1993 Cordella-Miele E, Miele L, Mukherjee AB. Identification of a specific region of low molecular weight phospholipases A2 (residues 21-40) as a potential target for structure-based design of inhibitors of these enzymes Proceedings of the National Academy of Sciences of the United States of America. 90: 10290-10294. PMID 7694288  0.68
1992 Mukherjee AB, Cordella-Miele E, Miele L. Regulation of extracellular phospholipase A2 activity: Implications for inflammatory diseases Dna and Cell Biology. 11: 233-243. PMID 1567556  0.68
1991 Chan CC, Ni M, Miele L, Cordella-Miele E, Ferrick M, Mukherjee AB, Nussenblatt RB. Effects of Antiflammins on Endotoxin-Induced Uveitis in Rats Archives of Ophthalmology. 109: 278-281. PMID 1993038 DOI: 10.1001/archopht.1991.01080020124058  0.68
1991 Facchiano A, Cordella-Miele E, Miele L, Mukherjee AB. Inhibition of pancreatic phospholipase A2 activity by uteroglobin and antiflammin peptides: Possible mechanism of action Life Sciences. 48: 453-464. PMID 1992287 DOI: 10.1016/0024-3205(91)90501-2  0.68
1991 Miele L, Strack B, Kruft V, Lanka E. Gene organization and nucleotide sequence of the primase region of incp plasmids RP4 and r751 Mitochondrial Dna. 2: 145-162. PMID 1818755 DOI: 10.3109/10425179109039685  0.68
1990 Miele L, Cordella-Miele E, Mukherjee AB. High level bacterial expression of uteroglobin, a dimeric eukaryotic protein with two interchain disulfide bridges, in its natural quaternary structure Journal of Biological Chemistry. 265: 6427-6435. PMID 2318861  0.68
1990 Miele L, Cordella-Miele E, Facchiano A, Mukherjee AB. Inhibition of phospholipase A2 by uteroglobin and antiflammin peptides Advances in Experimental Medicine and Biology. 279: 137-160. PMID 2151414  0.68
1990 Cordella-Miele E, Miele L, Beninati S, Mukherjee AB. Stimulation of phospholipases A2 by transglutaminases Advances in Experimental Medicine and Biology. 279: 105-123. PMID 1982917  0.68
1990 Cordella-Miele E, Miele L, Mukherjee AB. A novel transglutaminase-mediated post-translational modification of phospholipase A2 dramatically increases its catalytic activity Journal of Biological Chemistry. 265: 17180-17188. PMID 1976627  0.68
1990 Chan CC, Ni M, Miele L, Cordella-Miele E, Mukherjee AB, Nussenblatt RB. Antiflammins: Inhibition of endotoxin-induced uveitis in Lewis rats Ocular Immunology Today: Proceedings of the 5th International Symposium On the Immunology and Immunopathology of the Eye. Ics918. 467-470.  0.68
1989 Pulcini D, Stiuso P, Miele L, Della Pietra G, Colonna G. The molecular localization of non-tryptophan chromophores in calf lens crystallins. Biochimica Et Biophysica Acta. 995: 64-9. PMID 2923916 DOI: 10.1016/0167-4838(89)90234-3  0.68
1989 Vostal JG, Mukherjee AB, Miele L, Raphael Shulman N. Novel peptides derived from a region of local homology between uteroglobin and lipocortin-1 inhibit platelet aggregation and secretion Biochemical and Biophysical Research Communications. 165: 27-36. PMID 2531581 DOI: 10.1016/0006-291X(89)91029-2  0.68
1988 Stiuso P, Pulcini D, Ragone R, Miele L, Della Pietra G, Colonna G. Presence of nontryptophan fluorophores specifically bound to gamma 2-crystallin. Archives of Biochemistry and Biophysics. 266: 61-71. PMID 3178231 DOI: 10.1016/0003-9861(88)90236-6  0.68
1988 Miele L, Cordella-Miele E, Facchiano A, Mukherjee AB. Novel anti-inflammatory peptides from the region of highest similarity between uteroglobin and lipocortin I Nature. 335: 726-730. PMID 2971881  0.68
1988 Mukherjee AB, Cordella-Miele E, Kikukawa T, Miele L. Modulation of cellular response to antigens by uteroglobin and transglutaminase Advances in Experimental Medicine and Biology. 231: 135-152. PMID 2901190  0.68
1987 Miele L, Cordella-Miele E, Mukherjee AB. Uteroglobin: structure, molecular biology, and new perspectives on its function as a phospholipase A2 inhibitor Endocrine Reviews. 8: 474-490. PMID 3319534  0.68
1987 Pansegrau W, Miele L, Lurz R, Lanka E. Nucleotide sequence of the kanamycin resistance determinant of plasmid RP4: Homology to other aminoglycoside 3′-phosphotransferases Plasmid. 18: 193-204. PMID 2832861 DOI: 10.1016/0147-619X(87)90062-X  0.68
1984 Miele L, De Santis A, Abruzzese A. Polyamine levels in human malignant tumors Italian Journal of Biochemistry. 33.  0.68
1983 Libondi T, Rinaldi E, Miele L, Menzione M, Pulcino D, Della Pietra F, Auricchio G. Serum tryptophan in humans with senile cataracts Metabolic, Pediatric and Systemic Ophthalmology. 7: 75-79. PMID 6656619  0.68
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