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Liqiang Chen, Ph.D. - Publications

Affiliations: 
2002 University of Iowa, Iowa City, IA 
Area:
Organic Chemistry
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ding R, Zhang T, Wilson DJ, Xie J, Williams J, Xu Y, Ye Y, Chen L. Discovery of Irreversible p97 Inhibitors. Journal of Medicinal Chemistry. PMID 30830772 DOI: 10.1021/Acs.Jmedchem.9B00144  0.349
2016 Ding R, Zhang T, Xie J, Williams J, Ye Y, Chen L. Eeyarestatin I derivatives with improved aqueous solubility. Bioorganic & Medicinal Chemistry Letters. PMID 27729187 DOI: 10.1016/J.Bmcl.2016.09.068  0.313
2016 Ai T, Wilson DJ, More SS, Xie J, Chen L. 5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors. Journal of Medicinal Chemistry. PMID 26982234 DOI: 10.1021/Acs.Jmedchem.5B01376  0.387
2015 Ai T, Qiu L, Xie J, Geraghty RJ, Chen L. Design and synthesis of an activity-based protein profiling probe derived from cinnamic hydroxamic acid. Bioorganic & Medicinal Chemistry. PMID 26753813 DOI: 10.1016/J.Bmc.2015.12.035  0.312
2014 Cui H, Kamal Z, Ai T, Xu Y, More SS, Wilson DJ, Chen L. Discovery of potent and selective sirtuin 2 (SIRT2) inhibitors using a fragment-based approach. Journal of Medicinal Chemistry. 57: 8340-57. PMID 25275824 DOI: 10.1021/Jm500777S  0.404
2012 Ai T, Cui H, Chen L. Multi-Targeted Histone Deacetylase Inhibitors in Cancer Therapy Current Medicinal Chemistry. 19: 475-487. PMID 22204328 DOI: 10.2174/092986712798918842  0.313
2011 Chen L. Medicinal chemistry of sirtuin inhibitors. Current Medicinal Chemistry. 18: 1936-1946. PMID 21517778 DOI: 10.2174/092986711795590057  0.335
2011 Felczak K, Chen L, Wilson D, Williams J, Vince R, Petrelli R, Jayaram HN, Kusumanchi P, Kumar M, Pankiewicz KW. Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain. Bioorganic & Medicinal Chemistry. 19: 1594-605. PMID 21324702 DOI: 10.1016/J.Bmc.2011.01.042  0.308
2010 Chen L, Petrelli R, Gao G, Wilson DJ, McLean GT, Jayaram HN, Sham YY, Pankiewicz KW. Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylase based on a cinnamic hydroxamic acid core structure. Bioorganic & Medicinal Chemistry. 18: 5950-64. PMID 20650640 DOI: 10.1016/J.Bmc.2010.06.081  0.355
2010 Chen L, Wilson DJ, Xu Y, Aldrich CC, Felczak K, Sham YY, Pankiewicz KW. Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 53: 4768-78. PMID 20491506 DOI: 10.1021/Jm100424M  0.368
2009 Petrelli R, Sham YY, Chen L, Felczak K, Bennett E, Wilson D, Aldrich C, Yu JS, Cappellacci L, Franchetti P, Grifantini M, Mazzola F, Di Stefano M, Magni G, Pankiewicz KW. Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues. Bioorganic & Medicinal Chemistry. 17: 5656-64. PMID 19596199 DOI: 10.1016/J.Bmc.2009.06.013  0.534
2008 Chen L, Wilson DJ, Labello NP, Jayaram HN, Pankiewicz KW. Mycophenolic acid analogs with a modified metabolic profile. Bioorganic & Medicinal Chemistry. 16: 9340-5. PMID 18809333 DOI: 10.1016/J.Bmc.2008.08.062  0.304
2008 Neres J, Labello NP, Somu RV, Boshoff HI, Wilson DJ, Vannada J, Chen L, Barry CE, Bennett EM, Aldrich CC. Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues: structure-activity relationships of the nucleobase domain of 5'-O-[N-(salicyl)sulfamoyl]adenosine. Journal of Medicinal Chemistry. 51: 5349-70. PMID 18690677 DOI: 10.1021/Jm800567V  0.336
2008 Chen L, Petrelli R, Olesiak M, Wilson DJ, Labello NP, Pankiewicz KW. Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase. Bioorganic & Medicinal Chemistry. 16: 7462-9. PMID 18583139 DOI: 10.1016/J.Bmc.2008.06.003  0.334
2008 Chen L, Petrelli R, Felczak K, Olesiak M, Bennett EM, Magni G, Pankiewicz KW. Novel cofactor-type inhibitors of NAD-dependent enzymes. NAD-based therapeutics Collection of Czechoslovak Chemical Communications. 10: 71-79. DOI: 10.1135/Css200810071  0.326
2007 Chen L, Wilson D, Jayaram HN, Pankiewicz KW. Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylases for cancer treatment. Journal of Medicinal Chemistry. 50: 6685-91. PMID 18038969 DOI: 10.1021/Jm070864W  0.363
2007 Chen L, Gao G, Felczak K, Bonnac L, Patterson SE, Wilson D, Bennett EM, Jayaram HN, Hedstrom L, Pankiewicz KW. Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues. Journal of Medicinal Chemistry. 50: 5743-51. PMID 17958343 DOI: 10.1021/Jm070568J  0.345
2007 Witter DJ, Belvedere S, Chen L, Secrist JP, Mosley RT, Miller TA. Benzo[b]thiophene-based histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 4562-7. PMID 17576064 DOI: 10.1016/J.Bmcl.2007.05.091  0.312
2007 Bonnac L, Gao GY, Chen L, Felczak K, Bennett EM, Xu H, Kim T, Liu N, Oh H, Tonge PJ, Pankiewicz KW. Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry Letters. 17: 4588-91. PMID 17560106 DOI: 10.1016/J.Bmcl.2007.05.084  0.339
2007 Chen L, Gao G, Bonnac L, Wilson DJ, Bennett EM, Jayaram HN, Pankiewicz KW. Methylenebis(sulfonamide) linked nicotinamide adenine dinucleotide analogue as an inosine monophosphate dehydrogenase inhibitor. Bioorganic & Medicinal Chemistry Letters. 17: 3152-5. PMID 17395461 DOI: 10.1016/J.Bmcl.2007.03.035  0.357
2007 Bonnac L, Chen L, Pathak R, Gao G, Ming Q, Bennett E, Felczak K, Kullberg M, Patterson SE, Mazzola F, Magni G, Pankiewicz KW. Probing binding requirements of NAD kinase with modified substrate (NAD) analogues. Bioorganic & Medicinal Chemistry Letters. 17: 1512-5. PMID 17258457 DOI: 10.1016/J.Bmcl.2007.01.012  0.36
2006 Chen L, Rejman D, Bonnac L, Pankiewicz KW, Patterson SE. Nucleoside-5'-phosphoimidazolides: reagents for facile synthesis of dinucleoside pyrophosphates. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 13.4. PMID 18428947 DOI: 10.1002/0471142700.Nc1304S23  0.352
2006 Rejman D, Olesiak M, Chen L, Patterson SE, Wilson D, Jayaram HN, Hedstrom L, Pankiewicz KW. Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase. Journal of Medicinal Chemistry. 49: 5018-22. PMID 16884314 DOI: 10.1021/Jm060479R  0.346
2002 Chen L, Wiemer DF. Synthesis of a carbon analogue of N-acetylmannosamine via acetolysis on a relatively stable ozonide. The Journal of Organic Chemistry. 67: 7561-4. PMID 12375999 DOI: 10.1021/Jo020362K  0.481
2002 Chen L, Wiemer DF. Tandem reduction-reductive alkylation of azido sugars Tetrahedron Letters. 43: 2705-2708. DOI: 10.1016/S0040-4039(02)00386-6  0.457
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