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Jeffrey D. Neighbors, Ph.D. - Publications

Affiliations: 
2004 University of Iowa, Iowa City, IA 
Area:
Organic Chemistry
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Koubek EJ, Weissenrieder JS, Neighbors JD, Hohl RJ. Schweinfurthins: Lipid Modulators with Promising Anticancer Activity. Lipids. PMID 30334267 DOI: 10.1002/Lipd.12088  0.358
2017 Stockdale DP, Titunick MB, Biegler JM, Reed JL, Hartung AM, Wiemer DF, McLaughlin PJ, Neighbors JD. Selective opioid growth factor receptor antagonists based on a stilbene isostere. Bioorganic & Medicinal Chemistry. PMID 28693915 DOI: 10.1016/J.Bmc.2017.06.035  0.531
2016 Hartung AM, Navarro HA, Wiemer DF, Neighbors JD. Corrigendum to "A selective delta opioid receptor antagonist based on a stilbene core" [Bioorg. Med. Chem. Lett. 25 (2015) 5532-5535]. Bioorganic & Medicinal Chemistry Letters. 26: 1645. PMID 28750745 DOI: 10.1016/J.Bmcl.2016.02.014  0.488
2015 Hartung AM, Navarro HA, Wiemer DF, Neighbors JD. A selective delta opioid receptor antagonist based on a stilbene core. Bioorganic & Medicinal Chemistry Letters. 25: 5532-5. PMID 26525865 DOI: 10.1016/J.Bmcl.2015.10.059  0.532
2015 Kuder CH, Weivoda MM, Zhang Y, Zhu J, Neighbors JD, Wiemer DF, Hohl RJ. 3-Deoxyschweinfurthin B Lowers Cholesterol Levels by Decreasing Synthesis and Increasing Export in Cultured Cancer Cell Lines. Lipids. PMID 26494560 DOI: 10.1007/S11745-015-4083-Z  0.529
2014 Hartung AM, Beutler JA, Navarro HA, Wiemer DF, Neighbors JD. Stilbenes as κ-selective, non-nitrogenous opioid receptor antagonists. Journal of Natural Products. 77: 311-9. PMID 24456556 DOI: 10.1021/Np4009046  0.512
2012 Kuder CH, Sheehy RM, Neighbors JD, Wiemer DF, Hohl RJ. Functional evaluation of a fluorescent schweinfurthin: mechanism of cytotoxicity and intracellular quantification. Molecular Pharmacology. 82: 9-16. PMID 22461663 DOI: 10.1124/Mol.111.077107  0.528
2010 Topczewski JJ, Kuder CH, Neighbors JD, Hohl RJ, Wiemer DF. Fluorescent schweinfurthin B and F analogs with anti-proliferative activity. Bioorganic & Medicinal Chemistry. 18: 6734-41. PMID 20724169 DOI: 10.1016/J.Bmc.2010.07.056  0.699
2010 Topczewski JJ, Callahan MP, Neighbors JD, Wiemer DF. Synthesis of (+)-Angelichalcone Synfacts. 2010: 266-266. DOI: 10.1055/S-0029-1219253  0.601
2010 Topczewski JJ, Neighbors JD, Wiemer DF. ChemInform Abstract: Total Synthesis of (+)-Schweinfurthins B (I) and E (II). Cheminform. 41. DOI: 10.1002/chin.201005210  0.665
2009 Birt DF, Widrlechner MP, Hammer KD, Hillwig ML, Wei J, Kraus GA, Murphy PA, McCoy J, Wurtele ES, Neighbors JD, Wiemer DF, Maury WJ, Price JP. Hypericum in infection: Identification of anti-viral and anti-inflammatory constituents. Pharmaceutical Biology. 47: 774-782. PMID 19907671 DOI: 10.1080/13880200902988645  0.517
2009 Topczewski JJ, Callahan MP, Neighbors JD, Wiemer DF. A tandem cascade cyclization-electrophilic aromatic substitution: application in the total synthesis of (+)-angelichalcone. Journal of the American Chemical Society. 131: 14630-1. PMID 19824722 DOI: 10.1021/Ja906468V  0.725
2009 Topczewski JJ, Neighbors JD, Wiemer DF. Total synthesis of (+)-schweinfurthins B and E. The Journal of Organic Chemistry. 74: 6965-72. PMID 19697910 DOI: 10.1021/Jo901161M  0.74
2009 Maury W, Price JP, Brindley MA, Oh C, Neighbors JD, Wiemer DF, Wills N, Carpenter S, Hauck C, Murphy P, Widrlechner MP, Delate K, Kumar G, Kraus GA, Rizshsky L, et al. Identification of light-independent inhibition of human immunodeficiency virus-1 infection through bioguided fractionation of Hypericum perforatum. Virology Journal. 6: 101. PMID 19594941 DOI: 10.1186/1743-422X-6-101  0.475
2009 Kuder CH, Neighbors JD, Hohl RJ, Wiemer DF. Synthesis and biological activity of a fluorescent schweinfurthin analogue. Bioorganic & Medicinal Chemistry. 17: 4718-23. PMID 19464190 DOI: 10.1016/J.Bmc.2009.04.071  0.578
2009 Neighbors JD, Topczewski JJ, Swenson DC, Wiemer DF. Synthesis of the cis-fused hexahydroxanthene system via cationic cascade cyclization Tetrahedron Letters. 50: 3881-3884. DOI: 10.1016/J.Tetlet.2009.04.052  0.7
2008 Neighbors JD, Buller MJ, Boss KD, Wiemer DF. A concise synthesis of pawhuskin A. Journal of Natural Products. 71: 1949-52. PMID 18922035 DOI: 10.1021/Np800351C  0.624
2008 Mente NR, Neighbors JD, Wiemer DF. BF3 x Et2O-mediated cascade cyclizations: synthesis of schweinfurthins F and G. The Journal of Organic Chemistry. 73: 7963-70. PMID 18795788 DOI: 10.1021/Jo800951Q  0.722
2008 Hammer KD, Hillwig ML, Neighbors JD, Sim YJ, Kohut ML, Wiemer DF, Wurtele ES, Birt DF. Pseudohypericin is necessary for the light-activated inhibition of prostaglandin E2 pathways by a 4 component system mimicking an Hypericum perforatum fraction. Phytochemistry. 69: 2354-62. PMID 18707743 DOI: 10.1016/J.Phytochem.2008.06.010  0.515
2008 Neighbors JD, Mente NR, Boss KD, Zehnder DW, Wiemer DF. Synthesis of the schweinfurthin hexahydroxanthene core through Shi epoxidation Tetrahedron Letters. 49: 516-519. DOI: 10.1016/J.Tetlet.2007.11.086  0.727
2007 Mente NR, Wiemer AJ, Neighbors JD, Beutler JA, Hohl RJ, Wiemer DF. Total synthesis of (R,R,R)- and (S,S,S)-schweinfurthin F: differences of bioactivity in the enantiomeric series. Bioorganic & Medicinal Chemistry Letters. 17: 911-5. PMID 17236766 DOI: 10.1016/J.Bmcl.2006.11.096  0.686
2006 Neighbors JD, Salnikova MS, Beutler JA, Wiemer DF. Synthesis and structure-activity studies of schweinfurthin B analogs: Evidence for the importance of a D-ring hydrogen bond donor in expression of differential cytotoxicity. Bioorganic & Medicinal Chemistry. 14: 1771-84. PMID 16290161 DOI: 10.1016/J.Bmc.2005.10.025  0.612
2005 Neighbors JD, Beutler JA, Wiemer DF. Synthesis of nonracemic 3-deoxyschweinfurthin B. The Journal of Organic Chemistry. 70: 925-31. PMID 15675850 DOI: 10.1021/Jo048444R  0.622
2005 Neighbors JD, Salnikova MS, Wiemer DF. Total synthesis of pawhuskin C: A directed ortho metalation approach Tetrahedron Letters. 46: 1321-1324. DOI: 10.1016/J.Tetlet.2004.12.114  0.582
2002 Treadwell EM, Neighbors JD, Wiemer DF. A cascade cyclization approach to schweinfurthin B. Organic Letters. 4: 3639-42. PMID 12375907 DOI: 10.1021/Ol0266368  0.757
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