Robert M. Lawrence, Ph.D. - Publications

Affiliations: 
2011 Biochemistry Arizona State University, Tempe, AZ, United States 
Area:
Biochemistry, General Biophysics, Plant Physiology

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Li X, Chiu CY, Wang HJ, Kassemeyer S, Botha S, Shoeman RL, Lawrence RM, Kupitz C, Kirian R, James D, Wang D, Nelson G, Messerschmidt M, Boutet S, Williams GJ, et al. Corrigendum: Diffraction data of core-shell nanoparticles from an X-ray free electron laser. Scientific Data. 4: 170154. PMID 29064473 DOI: 10.1038/sdata.2017.154  0.68
2017 Li X, Chiu CY, Wang HJ, Kassemeyer S, Botha S, Shoeman RL, Lawrence RM, Kupitz C, Kirian R, James D, Wang D, Nelson G, Messerschmidt M, Boutet S, Williams GJ, et al. Diffraction data of core-shell nanoparticles from an X-ray free electron laser. Scientific Data. 4: 170048. PMID 28398334 DOI: 10.1038/sdata.2017.48  0.68
2016 Lawrence RM, Zook JD, Hogue BG. Full inactivation of alphaviruses in single particle and crystallized forms. Journal of Virological Methods. PMID 27465218 DOI: 10.1016/j.jviromet.2016.07.020  0.68
2016 Ma Z, Chao HJ, Turdi H, Hangeland JJ, Friends T, Kopcho LM, Lawrence RM, Cheng D. Characterization of Monoacylglycerol Acyltransferase 2 (MGAT2) Inhibitors by a Novel Probe in Binding Assays. Analytical Biochemistry. PMID 26925857 DOI: 10.1016/j.ab.2016.02.012  0.36
2016 Ding J, Lawrence RM, Jones PV, Hogue BG, Hayes MA. Concentration of Sindbis virus with optimized gradient insulator-based dielectrophoresis. The Analyst. PMID 26878279 DOI: 10.1039/c5an02430g  0.36
2015 Lawrence RM, Conrad CE, Zatsepin NA, Grant TD, Liu H, James D, Nelson G, Subramanian G, Aquila A, Hunter MS, Liang M, Boutet S, Coe J, Spence JC, Weierstall U, et al. Serial femtosecond X-ray diffraction of enveloped virus microcrystals. Structural Dynamics (Melville, N.Y.). 2: 041720. PMID 26798819 DOI: 10.1063/1.4929410  0.68
2015 Qiao JX, Wang TC, Adam L, Chen AY, Taylor D, Yang R, Zhuang S, Sleph PG, Li J, Li D, Yin X, Chang M, Chen XQ, Shen H, Li J, ... ... Lawrence RM, et al. Triphenylethanamine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors: Discovery of N-[(1R)-1-(3-cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide (BMS-795311). Journal of Medicinal Chemistry. PMID 26524347 DOI: 10.1021/acs.jmedchem.5b01363  0.36
2015 Onorato JM, Chu CH, Ma Z, Kopcho LM, Chao HJ, Lawrence RM, Cheng D. Cell-based assay of MGAT2-driven diacylglycerol synthesis for profiling inhibitors: use of a stable isotope-labeled substrate and high-resolution LC/MS. Journal of Lipid Research. 56: 747-53. PMID 25598079 DOI: 10.1194/jlr.D055020  0.36
2015 Lawrence RM, Conrad CE, Zatsepin NA, Grant TD, Liu H, James D, Nelson G, Subramanian G, Aquila A, Hunter MS, Liang M, Boutet S, Coe J, Spence JCH, Weierstall U, et al. Serial femtosecond X-ray diffraction of enveloped virus microcrystals Structural Dynamics. 2. DOI: 10.1063/1.4929410  0.68
2014 Lee HH, Cherni I, Yu H, Fromme R, Doran JD, Grotjohann I, Mittman M, Basu S, Deb A, Dörner K, Aquila A, Barty A, Boutet S, Chapman HN, Doak RB, ... ... Lawrence RM, et al. Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1. Iucrj. 1: 305-17. PMID 25295172 DOI: 10.1107/S2052252514014900  0.36
2014 Khandelwal P, Stryker S, Chao H, Aranibar N, Lawrence RM, Madireddi M, Zhao W, Chen L, Reily MD. 1H NMR-based lipidomics of rodent fur: species-specific lipid profiles and SCD1 inhibitor-related dermal toxicity. Journal of Lipid Research. 55: 1366-1374. PMID 24755647 DOI: 10.1194/jlr.M049155  0.36
2014 Wang Y, Yang W, Finlay HJ, Harikrishnan LS, Jiang J, Kamau MG, Van Kirk K, Nirschl DS, Taylor DS, Chen AY, Yin X, Sleph PG, Yang RZ, Huang CS, Adam LP, ... Lawrence RM, et al. Diphenylpyridylethanamine (DPPE)-based aminoheterocycles as cholesteryl ester transfer protein inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 860-4. PMID 24424134 DOI: 10.1016/j.bmcl.2013.12.088  0.36
2013 Chao H, Turdi H, Herpin TF, Roberge JY, Liu Y, Schnur DM, Poss MA, Rehfuss R, Hua J, Wu Q, Price LA, Abell LM, Schumacher WA, Bostwick JS, Steinbacher TE, ... ... Lawrence RM, et al. Discovery of 2-(phenoxypyridine)-3-phenylureas as small molecule P2Y1 antagonists. Journal of Medicinal Chemistry. 56: 1704-14. PMID 23368907 DOI: 10.1021/jm301708u  0.36
2012 Harikrishnan LS, Finlay HJ, Qiao JX, Kamau MG, Jiang J, Wang TC, Li J, Cooper CB, Poss MA, Adam LP, Taylor DS, Chen AY, Yin X, Sleph PG, Yang RZ, ... ... Lawrence RM, et al. Diphenylpyridylethanamine (DPPE) derivatives as cholesteryl ester transfer protein (CETP) inhibitors. Journal of Medicinal Chemistry. 55: 6162-75. PMID 22650305 DOI: 10.1021/jm300611v  0.36
2012 Kamau MG, Harikrishnan LS, Finlay HJ, Qiao JX, Jiang J, Poss MA, Salvati ME, Wexler RR, Lawrence RM. Synthesis of tertiary carbinamines Tetrahedron. 68: 2696-2703. DOI: 10.1016/j.tet.2012.01.050  0.36
2012 Ruan Z, Van Kirk K, Cooper CB, Lawrence RM, Poss M. One-Step Palladium-and Phenylsilane-Activated Amidation of Solid-Supported Ally Esters Solid-Phase Organic Syntheses. 2: 35-40. DOI: 10.1002/9781118336953.ch3  0.36
2011 Roongta UV, Pabalan JG, Wang X, Ryseck RP, Fargnoli J, Henley BJ, Yang WP, Zhu J, Madireddi MT, Lawrence RM, Wong TW, Rupnow BA. Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy. Molecular Cancer Research : McR. 9: 1551-61. PMID 21954435 DOI: 10.1158/1541-7786.MCR-11-0126  0.36
2011 Lawrence RM, Varco-Merth B, Bley CJ, Chen JJ, Fromme P. Recombinant production and purification of the subunit c of chloroplast ATP synthase. Protein Expression and Purification. 76: 15-24. PMID 21040791 DOI: 10.1016/j.pep.2010.10.009  0.36
2009 Roberge JY, Harikrishnan LS, Kamau MG, Ruan Z, Van Kirk K, Liu Y, Cooper CB, Poss MA, Dickson JK, Gavai AV, Chao ST, Leith LW, Bednarz MS, Mathur A, Kakarla R, ... ... Lawrence RM, et al. Design and synthesis of a G-protein-coupled receptor antagonist library of aryloxyalkanolamines using a polymer-supported acyclic acetal linker. Journal of Combinatorial Chemistry. 11: 72-82. PMID 19086798 DOI: 10.1021/cc800051u  0.36
2008 Seethala R, Peterson T, Dong J, Chu CH, Chen L, Golla R, Ma Z, Panemangalore R, Lawrence RM, Cheng D. A simple homogeneous scintillation proximity assay for acyl-coenzyme A:diacylglycerol acyltransferase. Analytical Biochemistry. 383: 144-50. PMID 18834848 DOI: 10.1016/j.ab.2008.09.013  0.36
2008 Cheng D, Iqbal J, Devenny J, Chu CH, Chen L, Dong J, Seethala R, Keim WJ, Azzara AV, Lawrence RM, Pelleymounter MA, Hussain MM. Acylation of acylglycerols by acyl coenzyme A:diacylglycerol acyltransferase 1 (DGAT1). Functional importance of DGAT1 in the intestinal fat absorption. The Journal of Biological Chemistry. 283: 29802-11. PMID 18768481 DOI: 10.1074/jbc.M800494200  0.36
2007 Li JJ, Wang H, Tino JA, Robl JA, Herpin TF, Lawrence RM, Biller S, Jamil H, Ponticiello R, Chen L, Chu CH, Flynn N, Cheng D, Zhao R, Chen B, et al. 2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 3208-11. PMID 17383874 DOI: 10.1016/j.bmcl.2007.03.017  0.36
2007 Roberge JY, Yu G, Mikkilineni A, Wu X, Zhu Y, Lawrence RM, Ewing WR. Synthesis of triazolopyridines and triazolopyrimidines using a modified Mitsunobu reaction Arkivoc. 2007: 132-147.  0.36
2006 Chen T, Knapp AC, Wu Y, Huang J, Lynch JS, Dickson JK, Lawrence RM, Feyen JH, Agler ML. High throughput screening identified a substituted imidazole as a novel RANK pathway-selective osteoclastogenesis inhibitor. Assay and Drug Development Technologies. 4: 387-96. PMID 16945012 DOI: 10.1089/adt.2006.4.387  0.36
2006 Kang L, McIntyre KW, Gillooly KM, Yang Y, Haycock J, Roberts S, Khanna A, Herpin TF, Yu G, Wu X, Morton GC, Tuerdi H, Koplowitz B, Walker SG, Wardwell-Swanson J, ... ... Lawrence RM, et al. A selective small molecule agonist of the melanocortin-1 receptor inhibits lipopolysaccharide-induced cytokine accumulation and leukocyte infiltration in mice Journal of Leukocyte Biology. 80: 897-904. PMID 16888084 DOI: 10.1189/jlb.1204748  0.36
2006 Ruan Z, Lawrence RM, Cooper CB. Phenylsilane as an active amidation reagent for the preparation of carboxamides and peptides Tetrahedron Letters. 47: 7649-7651. DOI: 10.1016/j.tetlet.2006.08.024  0.36
2005 Gavai AV, Vaz RJ, Mikkilineni AB, Roberge JY, Liu Y, Lawrence RM, Corte JR, Yang W, Bednarz M, Dickson JK, Ma Z, Seethala R, Feyen JH. Discovery of novel 1-arylmethyl pyrrolidin-2-yl ethanol amines as calcium-sensing receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 15: 5478-82. PMID 16216508 DOI: 10.1016/j.bmcl.2005.08.095  0.36
2005 Spires TE, Fink BE, Kick EK, You D, Rizzo CA, Takenaka I, Lawrence RM, Ruan Z, Salvati ME, Vite GD, Weinmann R, Attar RM, Gottardis MM, Lorenzi MV. Identification of novel functional inhibitors of 17beta-hydroxysteroid dehydrogenase type III (17beta-HSD3). The Prostate. 65: 159-70. PMID 15924334 DOI: 10.1002/pros.20279  0.36
2005 Yang W, Wang Y, Roberge JY, Ma Z, Liu Y, Michael Lawrence R, Rotella DP, Seethala R, Feyen JH, Dickson JK. Discovery and structure-activity relationships of 2-benzylpyrrolidine-substituted aryloxypropanols as calcium-sensing receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 15: 1225-8. PMID 15686947 DOI: 10.1016/j.bmcl.2004.11.071  0.36
2005 Bisacchi GS, Stein PD, Gougoutas JZ, Hartl KS, Lawrence RM, Liu E, Pudzianowski A, Schumacher WA, Sitkoff D, Steinbacher TE, Sutton J, Zhang Z, Seiler SM. Initial structure-activity relationships for a caprolactam-based series of neutral factor Xa inhibitors: Lead identification Letters in Drug Design and Discovery. 2: 625-630. DOI: 10.2174/157018005774717316  0.36
2004 Li JJ, Chao HG, Wang H, Tino JA, Lawrence RM, Ewing WR, Ma Z, Yan M, Slusarchyk D, Seethala R, Sun H, Li D, Burford NT, Stoffel RH, Salyan ME, et al. Discovery of a potent and novel motilin agonist. Journal of Medicinal Chemistry. 47: 1704-8. PMID 15027861 DOI: 10.1021/jm0304865  0.36
2003 Magnin DR, Biller SA, Wetterau J, Robl JA, Dickson JK, Taunk P, Harrity TW, Lawrence RM, Sun CQ, Wang T, Logan J, Fryszman O, Connolly F, Jolibois K, Kunselman L. Microsomal triglyceride transfer protein inhibitors: Discovery and synthesis of alkyl phosphonates as potent MTP inhibitors and cholesterol lowering agents Bioorganic and Medicinal Chemistry Letters. 13: 1337-1340. PMID 12657277 DOI: 10.1016/S0960-894X(03)00116-1  0.36
2003 Herpin TF, Yu G, Carlson KE, Morton GC, Wu X, Kang L, Tuerdi H, Khanna A, Tokarski JS, Lawrence RM, Macor JE. Discovery of tyrosine-based potent and selective melanocortin-1 receptor small-molecule agonists with anti-inflammatory properties Journal of Medicinal Chemistry. 46: 1123-1126. PMID 12646021 DOI: 10.1021/jm025600i  0.36
1998 Wetterau JR, Gregg RE, Harrity TW, Arbeeny C, Cap M, Connolly F, Chu CH, George RJ, Gordon DA, Jamil H, Jolibois KG, Kunselman LK, Lan SJ, Maccagnan TJ, Ricci B, ... ... Lawrence RM, et al. An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits. Science (New York, N.Y.). 282: 751-4. PMID 9784135 DOI: 10.1126/science.282.5389.751  0.36
1997 Lawrence RM, Biller SA, Fryszman OM, Poss MA. Automated synthesis and purification of amides: Exploitation of automated solid phase extraction in organic synthesis Synthesis. 553-558.  0.36
1996 Magnin DR, Biller SA, Chen Y, Dickson JK, Fryszman OM, Lawrence RM, Logan JV, Sieber-McMaster ES, Sulsky RB, Traeger SC, Hsieh DC, Lan SJ, Rinehart JK, Harrity TW, Jolibois KG, et al. alpha-Phosphonosulfonic acids: potent and selective inhibitors of squalene synthase. Journal of Medicinal Chemistry. 39: 657-60. PMID 8576905 DOI: 10.1021/jm9507340  0.36
1996 Lawrence RM, Biller SA, Dickson JK, Logan JVH, Magnin DR, Sulsky RB, DiMarco JD, Gougoutas JZ, Beyer BD, Taylor SC, Lan SJ, Ciosek CP, Harrity TW, Jolibois KG, Kunselman LK, et al. Enantioselective synthesis of α-phosphono sulfonate squalene synthase inhibitors: Chiral recognition in the interactions of an α-phosphono sulfonate inhibitor with squalene synthase Journal of the American Chemical Society. 118: 11668-11669. DOI: 10.1021/ja962505o  0.36
1996 Lawrence RM, Fryszman OM, Poss MA, Biller SA, Weller HN. Automated preparation and purification of amides American Biotechnology Laboratory. 14: 10-15.  0.36
1993 Ciosek CP, Magnin DR, Harrity TW, Logan JV, Dickson JK, Gordon EM, Hamilton KA, Jolibois KG, Kunselman LK, Lawrence RM. Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo. The Journal of Biological Chemistry. 268: 24832-7. PMID 8227045  0.36
1989 Whitesell JK, Lawrence RM. Stereocontrolled synthesis of peptide bond isosteres. Chirality. 1: 89-91. PMID 2642038 DOI: 10.1002/chir.530010116  0.36
1986 Whitesell JK, Lawrence RM, Chen HH. Auxiliary structure and asymmetric induction in the ene reactions of chiral glyoxylates Journal of Organic Chemistry. 51: 4779-4784.  0.36
1985 Whitesell JK, Chen HH, Lawrence RM. trans-2-phenylcyclohexanol. A powerful and readily available chiral auxiliary Journal of Organic Chemistry. 50: 4663-4664.  0.36
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