Nicholas A. Cacalano - Publications

Affiliations: 
Biomedical Physics 0119 University of California, Los Angeles, Los Angeles, CA 
Area:
Oncology, Molecular Biology, Cell Biology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lee S, Burner DN, Mendoza TR, Muldong MT, Arreola C, Wu CN, Cacalano NA, Kulidjian AA, Kane CJ, Jamieson CAM. Establishment and Analysis of Three-Dimensional (3D) Organoids Derived from Patient Prostate Cancer Bone Metastasis Specimens and their Xenografts. Journal of Visualized Experiments : Jove. PMID 32065165 DOI: 10.3791/60367  0.301
2019 Kaur K, Kozlowska AK, Topchyan P, Ko MW, Ohanian N, Chiang J, Cook J, Maung PO, Park SH, Cacalano N, Fang C, Jewett A. Probiotic-Treated Super-Charged NK Cells Efficiently Clear Poorly Differentiated Pancreatic Tumors in Hu-BLT Mice. Cancers. 12. PMID 31878338 DOI: 10.3390/Cancers12010063  0.343
2019 Li Q, Wang H, Peng H, Huyan T, Cacalano NA. Exosomes: Versatile Nano Mediators of Immune Regulation. Cancers. 11. PMID 31615107 DOI: 10.3390/Cancers11101557  0.381
2019 Zhang H, Wang S, Cacalano N, Zhu H, Liu Q, Xie M, Kamrava M, Konecny G, Jin S. Oncogenic Y68 frame shift mutation of PTEN represents a mechanism of docetaxel resistance in endometrial cancer cell lines. Scientific Reports. 9: 2111. PMID 30765787 DOI: 10.1038/S41598-019-38585-9  0.358
2018 Muldong M, Jamieson CA, Deichaite I, Lewis A, Anderson DW, Long YO, Cacalano NA. Abstract B49: Novel epidermal growth factor receptor inhibitors cross the blood-brain barrier and inhibit the growth of metastatic non-small cell lung cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-B49  0.304
2016 Kozlowska AK, Tseng HC, Kaur K, Topchyan P, Inagaki A, Bui VT, Kasahara N, Cacalano N, Jewett A. Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural killer cells. Cancer Immunology, Immunotherapy : Cii. PMID 27439500 DOI: 10.1007/S00262-016-1866-X  0.394
2016 Cacalano NA. Regulation of Natural Killer Cell Function by STAT3. Frontiers in Immunology. 7: 128. PMID 27148255 DOI: 10.3389/Fimmu.2016.00128  0.428
2016 Jamieson CA, Muldong M, Long YO, Deichaite I, Lewis A, Anderson DW, Cacalano NA. Novel epidermal growth factor receptor inhibitor accumulates in the brain and inhibits the growth of brain metastatic non-small cell lung cancer Journal of Thoracic Oncology. 11: S17-S18. DOI: 10.1016/J.Jtho.2015.12.030  0.388
2015 Tseng HC, Inagaki A, Bui VT, Cacalano N, Kasahara N, Man YG, Jewett A. Differential Targeting of Stem Cells and Differentiated Glioblastomas by NK Cells. Journal of Cancer. 6: 866-76. PMID 26284138 DOI: 10.7150/Jca.11527  0.378
2015 Tseng HC, Cacalano N, Jewett A. Split anergized Natural Killer cells halt inflammation by inducing stem cell differentiation, resistance to NK cell cytotoxicity and prevention of cytokine and chemokine secretion. Oncotarget. 6: 8947-59. PMID 25860927 DOI: 10.18632/Oncotarget.3250  0.418
2015 Kim MH, Kim MS, Kim W, Kang MA, Cacalano NA, Kang SB, Shin YJ, Jeong JH. Suppressor of cytokine signaling (SOCS) genes are silenced by DNA hypermethylation and histone deacetylation and regulate response to radiotherapy in cervical cancer cells. Plos One. 10: e0123133. PMID 25849377 DOI: 10.1371/Journal.Pone.0123133  0.433
2014 Tseng HC, Bui V, Man YG, Cacalano N, Jewett A. Induction of Split Anergy Conditions Natural Killer Cells to Promote Differentiation of Stem Cells through Cell-Cell Contact and Secreted Factors. Frontiers in Immunology. 5: 269. PMID 24995006 DOI: 10.3389/Fimmu.2014.00269  0.406
2014 Jewett A, Man YG, Cacalano N, Kos J, Tseng HC. Natural killer cells as effectors of selection and differentiation of stem cells: role in resolution of inflammation. Journal of Immunotoxicology. 11: 297-307. PMID 24575813 DOI: 10.3109/1547691X.2013.877104  0.386
2014 Jiang S, Coppola G, Mose E, Lowy A, Jamieson C, Cacalano N. Abstract A10: Suppressor of cytokine signaling (SOCS)-3 and the C-X-C chemokines CXCL1 and CXCL2 promote tumor aggressiveness and radiation resistance in pancreatic cancer Cancer Research. 74: 4208-4208. DOI: 10.1158/1557-3125.Modorg-A10  0.603
2014 Jiang S, Mose E, Coppola G, Lowy A, Jamieson C, Cacalano NA. Abstract 4208: Suppressor of Cytokine Signaling (SOCS)-3 and the C-X-C chemokines CXCL1 and CXCL2 promote tumor aggessiveness and radiation resistance in pancreatic cancer Molecular and Cellular Biology. DOI: 10.1158/1538-7445.Am2014-4208  0.549
2012 Jewett A, Tseng HC, Arasteh A, Saadat S, Christensen RE, Cacalano NA. Natural killer cells preferentially target cancer stem cells; role of monocytes in protection against NK cell mediated lysis of cancer stem cells. Current Drug Delivery. 9: 5-16. PMID 22023212 DOI: 10.2174/156720112798375989  0.411
2011 Huynh T, Kapur RV, Kaplan CW, Cacalano N, Kinder Haake S, Shi W, Sieling P, Jewett A. The role of aggregation in Fusobacterium nucleatum- induced immune cell death. Journal of Endodontics. 37: 1531-5. PMID 22000457 DOI: 10.1016/J.Joen.2011.06.034  0.335
2011 Cacalano NA, Jiang S. Abstract 2888: SOCS3-deficient cells are defective in the DNA damage response Cancer Research. 71: 2888-2888. DOI: 10.1158/1538-7445.Am2011-2888  0.654
2011 Jamieson C, Petrigliano F, Belanto J, Virk M, Coppola G, Tchieu J, Fu E, Magyar C, Raheem O, Kazarian M, Morris S, Cacalano N, Geschwind D, Tetradis S, Jamieson C, et al. 1451 GENOME-WIDE EXPRESSION PROFILING OF CASTRATION-RESISTANT PROSTATE CANCER XENOGRAFTS IN THE BONE-NICHE REVEALED UP-REGULATION OF THE ANTI-APOPTOSIS GENE, YWHAZ, A NETWORK MODULE HUB GENE Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1364  0.323
2010 Sherman MH, Kuraishy AI, Deshpande C, Hong JS, Cacalano NA, Gatti RA, Manis JP, Damore MA, Pellegrini M, Teitell MA. AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling. Molecular Cell. 39: 873-85. PMID 20864035 DOI: 10.1016/J.Molcel.2010.08.019  0.397
2010 Tseng HC, Arasteh A, Paranjpe A, Teruel A, Yang W, Behel A, Alva JA, Walter G, Head C, Ishikawa TO, Herschman HR, Cacalano N, Pyle AD, Park NH, Jewett A. Increased lysis of stem cells but not their differentiated cells by natural killer cells; de-differentiation or reprogramming activates NK cells. Plos One. 5: e11590. PMID 20661281 DOI: 10.1371/Journal.Pone.0011590  0.376
2010 Mussano F, Lee KJ, Zuk P, Tran L, Cacalano NA, Jewett A, Carossa S, Nishimura I. Differential effect of ionizing radiation exposure on multipotent and differentiation-restricted bone marrow mesenchymal stem cells. Journal of Cellular Biochemistry. 111: 322-32. PMID 20506196 DOI: 10.1002/Jcb.22699  0.387
2010 Jewett A, Arasteh A, Tseng HC, Behel A, Arasteh H, Yang W, Cacalano NA, Paranjpe A. Strategies to rescue mesenchymal stem cells (MSCs) and dental pulp stem cells (DPSCs) from NK cell mediated cytotoxicity. Plos One. 5: e9874. PMID 20360990 DOI: 10.1371/Journal.Pone.0009874  0.384
2010 Belanto JJ, Diaz-Perez SV, Magyar CE, Maxwell MM, Yilmaz Y, Topp K, Boso G, Jamieson CH, Cacalano NA, Jamieson CA. Dexamethasone induces dysferlin in myoblasts and enhances their myogenic differentiation. Neuromuscular Disorders : Nmd. 20: 111-21. PMID 20080405 DOI: 10.1016/J.Nmd.2009.12.003  0.35
2009 Paranjpe A, Cacalano NA, Hume WR, Jewett A. N-acetyl cysteine mediates protection from 2-hydroxyethyl methacrylate induced apoptosis via nuclear factor kappa B-dependent and independent pathways: potential involvement of JNK. Toxicological Sciences : An Official Journal of the Society of Toxicology. 108: 356-66. PMID 19176594 DOI: 10.1093/Toxsci/Kfp010  0.392
2008 Cacalano NA, Le D, Paranjpe A, Wang MY, Fernandez A, Evazyan T, Park NH, Jewett A. Regulation of IGFBP6 gene and protein is mediated by the inverse expression and function of c-jun N-terminal kinase (JNK) and NFkappaB in a model of oral tumor cells. Apoptosis : An International Journal On Programmed Cell Death. 13: 1439-49. PMID 18982452 DOI: 10.1007/S10495-008-0270-1  0.402
2008 Paranjpe A, Cacalano NA, Hume WR, Jewett A. Mechanisms of N-acetyl cysteine-mediated protection from 2-hydroxyethyl methacrylate-induced apoptosis. Journal of Endodontics. 34: 1191-7. PMID 18793918 DOI: 10.1016/J.Joen.2008.06.011  0.327
2008 Sitko JC, Yeh B, Kim M, Zhou H, Takaesu G, Yoshimura A, McBride WH, Jewett A, Jamieson CA, Cacalano NA. SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage. Cellular Signalling. 20: 2221-30. PMID 18793717 DOI: 10.1016/J.Cellsig.2008.08.011  0.717
2008 Paranjpe A, Sung EC, Cacalano NA, Hume WR, Jewett A. N-acetyl cysteine protects pulp cells from resin toxins in vivo. Journal of Dental Research. 87: 537-41. PMID 18502961 DOI: 10.1177/154405910808700603  0.35
2008 Kim K, Brush JM, Watson PA, Cacalano NA, Iwamoto KS, McBride WH. Epidermal growth factor receptor vIII expression in U87 glioblastoma cells alters their proteasome composition, function, and response to irradiation. Molecular Cancer Research : McR. 6: 426-34. PMID 18337449 DOI: 10.1158/1541-7786.Mcr-07-0313  0.411
2008 Jewett A, Teruel A, Romero M, Head C, Cacalano N. Rapid and potent induction of cell death and loss of NK cell cytotoxicity against oral tumors by F(ab')2 fragment of anti-CD16 antibody. Cancer Immunology, Immunotherapy : Cii. 57: 1053-66. PMID 18188563 DOI: 10.1007/S00262-007-0437-6  0.362
2008 Teruel A, Romero M, Cacalano NA, Head C, Jewett A. Potential contribution of naïve immune effectors to oral tumor resistance: role in synergistic induction of VEGF, IL-6, and IL-8 secretion. Cancer Immunology, Immunotherapy : Cii. 57: 359-66. PMID 17703300 DOI: 10.1007/S00262-007-0375-3  0.359
2008 Sitko J, Yeh B, Kim M, Zhou H, Takaesu G, Yoshimura A, McBride W, Jewett A, Jamieson C, Cacalano N. SOCS3 Regulates p21 Expression and Cell Cycle Arrest in Response to Radiation-induced DNA Damage International Journal of Radiation Oncology*Biology*Physics. 72: S693. DOI: 10.1016/J.Ijrobp.2008.06.589  0.705
2007 Paranjpe A, Cacalano NA, Hume WR, Jewett A. N-acetylcysteine protects dental pulp stromal cells from HEMA-induced apoptosis by inducing differentiation of the cells. Free Radical Biology & Medicine. 43: 1394-408. PMID 17936186 DOI: 10.1016/J.Freeradbiomed.2007.07.011  0.396
2007 Romero-Reyes M, Head C, Cacalano NA, Jewett A. Potent induction of TNF-alpha during interaction of immune effectors with oral tumors as a potential mechanism for the loss of NK cell viability and function. Apoptosis : An International Journal On Programmed Cell Death. 12: 2063-75. PMID 17713857 DOI: 10.1007/S10495-007-0112-6  0.319
2007 Zhou H, Miki R, Eeva M, Fike FM, Seligson D, Yang L, Yoshimura A, Teitell MA, Jamieson CA, Cacalano NA. Reciprocal regulation of SOCS 1 and SOCS3 enhances resistance to ionizing radiation in glioblastoma multiforme. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2344-53. PMID 17438093 DOI: 10.1158/1078-0432.Ccr-06-2303  0.476
2007 Cui X, Zhang L, Luo J, Rajasekaran A, Hazra S, Cacalano N, Dubinett SM. Unphosphorylated STAT6 contributes to constitutive cyclooxygenase-2 expression in human non-small cell lung cancer. Oncogene. 26: 4253-60. PMID 17237818 DOI: 10.1038/Sj.Onc.1210222  0.449
2006 Jewett A, Head C, Cacalano NA. Emerging mechanisms of immunosuppression in oral cancers. Journal of Dental Research. 85: 1061-73. PMID 17122156 DOI: 10.1177/154405910608501201  0.386
2006 Wang CC, Liao YP, Mischel PS, Iwamoto KS, Cacalano NA, McBride WH. HDJ-2 as a target for radiosensitization of glioblastoma multiforme cells by the farnesyltransferase inhibitor R115777 and the role of the p53/p21 pathway. Cancer Research. 66: 6756-62. PMID 16818651 DOI: 10.1158/0008-5472.Can-06-0185  0.398
2006 Jewett A, Cacalano NA, Head C, Teruel A. Coengagement of CD16 and CD94 receptors mediates secretion of chemokines and induces apoptotic death of naive natural killer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1994-2003. PMID 16609008 DOI: 10.1158/1078-0432.Ccr-05-2306  0.31
2006 Jewett A, Cacalano NA, Teruel A, Romero M, Rashedi M, Wang M, Nakamura H. Inhibition of nuclear factor kappa B (NFkappaB) activity in oral tumor cells prevents depletion of NK cells and increases their functional activation. Cancer Immunology, Immunotherapy : Cii. 55: 1052-63. PMID 16328384 DOI: 10.1007/S00262-005-0093-7  0.423
2006 Geron I, Barroga C, Gotlib J, Kavalerchik E, Abrahamsson A, Goff D, Cacalano N, Hood J, Soll R, Noronha G, Tefferi A, Weissman IL, Kaushansky K, Jamieson C. Inhibition of JAK2 V617F-Induced Erythroid Skewing of Hematopoietic Stem Cell Differentiation with a Selective JAK2 Antagonist. Blood. 108: 3616-3616. DOI: 10.1182/Blood.V108.11.3616.3616  0.349
2005 Dalwadi H, Krysan K, Heuze-Vourc'h N, Dohadwala M, Elashoff D, Sharma S, Cacalano N, Lichtenstein A, Dubinett S. Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 7674-82. PMID 16278387 DOI: 10.1158/1078-0432.Ccr-05-1205  0.382
2004 Sitko JC, Guevara CI, Cacalano NA. Tyrosine-phosphorylated SOCS3 interacts with the Nck and Crk-L adapter proteins and regulates Nck activation. The Journal of Biological Chemistry. 279: 37662-9. PMID 15173187 DOI: 10.1074/Jbc.M404007200  0.686
2003 Haan S, Ferguson P, Sommer U, Hiremath M, McVicar DW, Heinrich PC, Johnston JA, Cacalano NA. Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation. The Journal of Biological Chemistry. 278: 31972-9. PMID 12783885 DOI: 10.1074/Jbc.M303170200  0.349
2001 Cacalano NA, Sanden D, Johnston JA. Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras Nature Cell Biology. 3: 460-465. PMID 11331873 DOI: 10.1038/35074525  0.388
1999 Cacalano NA, Johnston JA. Interleukin-2 signaling and inherited immunodeficiency American Journal of Human Genetics. 65: 287-293. PMID 10417270 DOI: 10.1086/302518  0.403
1999 Cohney SJ, Sanden D, Cacalano NA, Yoshimura A, Mui A, Migone TS, Johnston JA. SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation Molecular and Cellular Biology. 19: 4980-4988. PMID 10373548 DOI: 10.1128/Mcb.19.7.4980  0.328
1999 Cacalano NA, Migone TS, Bazan F, Hanson EP, Chen M, Candotti F, O'Shea JJ, Johnston JA. Autosomal SCID caused by a point mutation in the N-terminus of Jak3: Mapping of the Jak3-receptor interaction domain Embo Journal. 18: 1549-1558. PMID 10075926 DOI: 10.1093/Emboj/18.6.1549  0.33
1998 Migone TS, Rodig S, Cacalano NA, Berg M, Schreiber RD, Leonard WJ. Functional cooperation of the interleukin-2 receptor β chain and Jak1 in phosphatidylinositol 3-kinase recruitment and phosphorylation Molecular and Cellular Biology. 18: 6416-6422. PMID 9774657 DOI: 10.1128/Mcb.18.11.6416  0.304
1998 Migone TS, Cacalano NA, Taylor N, Yi T, Waldmann TA, Johnston JA. Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells Proceedings of the National Academy of Sciences of the United States of America. 95: 3845-3850. PMID 9520455 DOI: 10.1073/Pnas.95.7.3845  0.36
Show low-probability matches.