Yung H. Wong - Publications

Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 

180 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tse LH, Wong YH. Modeling the Heterodimer Interfaces of Melatonin Receptors. Frontiers in Cellular Neuroscience. 15: 725296. PMID 34690701 DOI: 10.3389/fncel.2021.725296  0.329
2020 Chung YK, Wong YH. Re-examining the 'Dissociation Model' of G protein activation from the perspective of Gβγ signaling. The Febs Journal. PMID 33085809 DOI: 10.1111/febs.15605  0.329
2020 Li Y, Liu W, Saini V, Wong YH. Mutations at the dimer interface and surface residues of Nm23-H1 metastasis suppressor affect its expression and function. Molecular and Cellular Biochemistry. PMID 32705629 DOI: 10.1007/S11010-020-03836-1  0.301
2020 Chan KH, Tse LH, Huang X, Wong YH. Molecular basis defining the selectivity of substituted isoquinolinones for the melatonin MT receptor. Biochemical Pharmacology. 114020. PMID 32389636 DOI: 10.1016/J.Bcp.2020.114020  0.406
2020 Dong K, Goyarts E, Rella A, Pelle E, Wong YH, Pernodet N. Age Associated Decrease of MT-1 Melatonin Receptor in Human Dermal Skin Fibroblasts Impairs Protection Against UV-Induced DNA Damage. International Journal of Molecular Sciences. 21. PMID 31947744 DOI: 10.3390/Ijms21010326  0.331
2019 Tse LH, Wong YH. GPCRs in Autocrine and Paracrine Regulations. Frontiers in Endocrinology. 10: 428. PMID 31354618 DOI: 10.3389/Fendo.2019.00428  0.454
2017 Li Y, Song J, Tong Y, Chung SK, Wong YH. RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway. Oncotarget. 8: 69945-69960. PMID 29050254 DOI: 10.18632/Oncotarget.19509  0.418
2017 Li Y, Song J, Tong Y, Kim Chung S, Wong YH. RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway. Oncotarget. PMID 28779067 DOI: 10.18632/oncotarget.19509  0.307
2017 Leung CCY, Wong YH. Role of G Protein-Coupled Receptors in the Regulation of Structural Plasticity and Cognitive Function. Molecules (Basel, Switzerland). 22. PMID 28737723 DOI: 10.3390/Molecules22071239  0.366
2016 Yang L, Lee MM, Leung MM, Wong YH. Regulator of G protein signaling 20 enhances cancer cell aggregation, migration, invasion and adhesion. Cellular Signalling. PMID 27495875 DOI: 10.1016/J.Cellsig.2016.07.017  0.352
2016 Chan AS, Lau WW, Szeto A, Wang J, Wong YH. Differential regulation of CXCL8 production by different G protein subunits with synergistic stimulation by Gi- and Gq-regulated pathways. Journal of Molecular Biology. PMID 27040396 DOI: 10.1016/J.Jmb.2016.03.026  0.483
2016 Xu ML, Bi CW, Kong AY, Dong TT, Wong YH, Tsim KW. Flavonoids induce the expression of acetylcholinesterase in cultured osteoblasts. Chemico-Biological Interactions. PMID 27019979 DOI: 10.1016/J.Cbi.2016.03.025  0.351
2016 Li S, Yang C, Zhang L, Gao X, Wang X, Liu W, Wang Y, Jiang S, Wong YH, Zhang Y, Liu K. Promoting axon regeneration in the adult CNS by modulation of the melanopsin/GPCR signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831088 DOI: 10.1073/Pnas.1523645113  0.318
2015 Kwan DH, Wong KM, Chan AS, Yung LY, Wong YH. An intact helical domain is required for Gα14 to stimulate phospholipase Cβ. Bmc Structural Biology. 15: 18. PMID 26377666 DOI: 10.1186/S12900-015-0043-3  0.33
2015 Tse MK, Morris CJ, Zhang M, Wong YH. Activator of G protein signaling 3 forms a complex with resistance to inhibitors of cholinesterase-8A without promoting nucleotide exchange on Gα(i3). Molecular and Cellular Biochemistry. 401: 27-38. PMID 25480567 DOI: 10.1007/S11010-014-2289-7  0.318
2014 Hu Y, Chan KH, He X, Ho MK, Wong YH. Synthesis and functional characterization of substituted isoquinolinones as MT2-selective melatoninergic ligands. Plos One. 9: e113638. PMID 25479338 DOI: 10.1371/Journal.Pone.0113638  0.375
2014 Tse KH, Chow KB, Leung WK, Wong YH, Wise H. Primary sensory neurons regulate Toll-like receptor-4-dependent activity of glial cells in dorsal root ganglia. Neuroscience. 279: 10-22. PMID 25171787 DOI: 10.1016/J.Neuroscience.2014.08.033  0.337
2014 Ip FC, Ng YP, An HJ, Dai Y, Pang HH, Hu YQ, Chin AC, Harley CB, Wong YH, Ip NY. Cycloastragenol is a potent telomerase activator in neuronal cells: implications for depression management. Neuro-Signals. 22: 52-63. PMID 25095809 DOI: 10.1159/000365290  0.349
2014 Tse KH, Chow KB, Leung WK, Wong YH, Wise H. Lipopolysaccharide differentially modulates expression of cytokines and cyclooxygenases in dorsal root ganglion cells via Toll-like receptor-4 dependent pathways. Neuroscience. 267: 241-51. PMID 24607321 DOI: 10.1016/J.Neuroscience.2014.02.041  0.401
2013 Chan KH, Wong YH. A molecular and chemical perspective in defining melatonin receptor subtype selectivity International Journal of Molecular Sciences. 14: 18385-18406. PMID 24018885 DOI: 10.3390/Ijms140918385  0.442
2013 Zuo H, Chan AS, Ammer H, Wong YH. Activation of Gαq subunits up-regulates the expression of the tumor suppressor Fhit. Cellular Signalling. 25: 2440-52. PMID 23993961 DOI: 10.1016/J.Cellsig.2013.08.019  0.421
2013 Zuo H, Chan GP, Zhu J, Yeung WW, Chan AS, Ammer H, Wong YH. Activation state-dependent interaction between Gαq subunits and the Fhit tumor suppressor. Cell Communication and Signaling : Ccs. 11: 59. PMID 23947369 DOI: 10.1186/1478-811X-11-59  0.372
2013 Wang Y, Tong Y, Tso PH, Wong YH. Regulator of G protein signaling 19 suppresses Ras-induced neoplastic transformation and tumorigenesis. Cancer Letters. 339: 33-41. PMID 23911936 DOI: 10.1016/J.Canlet.2013.07.025  0.332
2013 Lau WW, Chan AS, Poon LS, Zhu J, Wong YH. Gβγ-mediated activation of protein kinase D exhibits subunit specificity and requires Gβγ-responsive phospholipase Cβ isoforms. Cell Communication and Signaling : Ccs. 11: 22. PMID 23561540 DOI: 10.1186/1478-811X-11-22  0.492
2013 Tso PH, Wang Y, Yung LY, Tong Y, Lee MM, Wong YH. RGS19 inhibits Ras signaling through Nm23H1/2-mediated phosphorylation of the kinase suppressor of Ras. Cellular Signalling. 25: 1064-74. PMID 23416464 DOI: 10.1016/J.Cellsig.2013.02.010  0.401
2013 Chan KH, Hu Y, Ho MK, Wong YH. Characterization of substituted phenylpropylamides as highly selective agonists at the melatonin MT2 receptor. Current Medicinal Chemistry. 20: 289-300. PMID 23131177 DOI: 10.2174/092986713804806649  0.418
2013 Ng KY, Yeung BH, Wong YH, Wise H. Isolated dorsal root ganglion neurones inhibit receptor-dependent adenylyl cyclase activity in associated glial cells. British Journal of Pharmacology. 168: 746-60. PMID 22924655 DOI: 10.1111/J.1476-5381.2012.02177.X  0.446
2013 Tse MK, Wong YH. Neuronal functions of activators of G protein signaling. Neuro-Signals. 21: 259-71. PMID 22571923 DOI: 10.1159/000337263  0.429
2012 Lee MM, Chui RK, Tam IY, Lau AH, Wong YH. CCR1-mediated STAT3 tyrosine phosphorylation and CXCL8 expression in THP-1 macrophage-like cells involve pertussis toxin-insensitive Gα(14/16) signaling and IL-6 release. Journal of Immunology (Baltimore, Md. : 1950). 189: 5266-76. PMID 23125416 DOI: 10.4049/Jimmunol.1103359  0.407
2012 Hoffmann F, Müller W, Schütz D, Penfold ME, Wong YH, Schulz S, Stumm R. Rapid uptake and degradation of CXCL12 depend on CXCR7 carboxyl-terminal serine/threonine residues. The Journal of Biological Chemistry. 287: 28362-77. PMID 22736769 DOI: 10.1074/Jbc.M111.335679  0.449
2012 Kwan DH, Yung LY, Ye RD, Wong YH. Activation of Ras-dependent signaling pathways by G(14) -coupled receptors requires the adaptor protein TPR1. Journal of Cellular Biochemistry. 113: 3486-97. PMID 22711498 DOI: 10.1002/Jcb.24225  0.463
2012 Lau AH, Lai HK, Yeung BH, Leung SL, Tsang SY, Wong YH, Wise H. Prostacyclin receptor-dependent inhibition of human erythroleukemia cell differentiation is STAT3-dependent. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 86: 119-26. PMID 22336225 DOI: 10.1016/J.Plefa.2011.12.002  0.472
2012 Yung LY, Lam WS, Ho MK, Hu Y, Ip FC, Pang H, Chin AC, Harley CB, Ip NY, Wong YH. Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types. Planta Medica. 78: 115-21. PMID 22083896 DOI: 10.1055/S-0031-1280346  0.43
2012 Ip AK, Tso PH, Lee MM, Wong YH. Elevated expression of RGS19 impairs the responsiveness of stress-activated protein kinases to serum. Molecular and Cellular Biochemistry. 362: 159-68. PMID 22045062 DOI: 10.1007/S11010-011-1138-1  0.447
2012 Lau WW, Ng JK, Lee MM, Chan AS, Wong YH. Interleukin-6 autocrine signaling mediates melatonin MT(1/2) receptor-induced STAT3 Tyr(705) phosphorylation. Journal of Pineal Research. 52: 477-89. PMID 21954831 DOI: 10.1111/J.1600-079X.2011.00965.X  0.481
2011 Wan G, Zhou L, Lim Q', Wong YH, Too HP. Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. Cellular Signalling. 23: 1727-37. PMID 21723942 DOI: 10.1016/J.Cellsig.2011.06.007  0.471
2011 Tso PH, Yung LY, Wang Y, Wong YH. RGS19 stimulates cell proliferation by deregulating cell cycle control and enhancing Akt signaling. Cancer Letters. 309: 199-208. PMID 21705135 DOI: 10.1016/J.Canlet.2011.06.002  0.424
2011 Ng KY, Wong YH, Wise H. Glial cells isolated from dorsal root ganglia express prostaglandin E(2) (EP(4)) and prostacyclin (IP) receptors. European Journal of Pharmacology. 661: 42-8. PMID 21549696 DOI: 10.1016/J.Ejphar.2011.04.040  0.427
2011 Liu AM, Lo RKh, Guo EX, Ho MK, Ye RD, Wong YH. Gα16 interacts with tetratricopeptide repeat 1 (TPR1) through its β3 region to activate Ras independently of phospholipase Cβ signaling. Bmc Structural Biology. 11: 17. PMID 21486497 DOI: 10.1186/1472-6807-11-17  0.39
2011 Zhu J, Hu Y, Ho MK, Wong YH. 3-Methoxylphenylpropyl amides as novel receptor subtype-selective melatoninergic ligands: characterization of physicochemical and pharmacokinetic properties. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 41: 35-45. PMID 21110748 DOI: 10.3109/00498254.2010.524264  0.341
2011 Zhang H, Wong YH, Wang H, Chen Z, Arellano SM, Ravasi T, Qian PY. Quantitative proteomics identify molecular targets that are crucial in larval settlement and metamorphosis of Bugula neritina. Journal of Proteome Research. 10: 349-60. PMID 21090758 DOI: 10.1021/Pr100817V  0.304
2011 Mei H, Ho MK, Yung LY, Wu Z, Ip NY, Wong YH. Expression of Gα(z) in C2C12 cells restrains myogenic differentiation. Cellular Signalling. 23: 389-97. PMID 20946953 DOI: 10.1016/J.Cellsig.2010.10.009  0.37
2010 Qian PY, Wong YH, Zhang Y. Changes in the proteome and phosphoproteome expression in the bryozoan Bugula neritina larvae in response to the antifouling agent butenolide. Proteomics. 10: 3435-46. PMID 20827734 DOI: 10.1002/Pmic.201000199  0.32
2010 Liu AM, Lo RK, Lee MM, Wang Y, Yeung WW, Ho MK, Su Y, Ye RD, Wong YH. Galpha16 activates Ras by forming a complex with tetratricopeptide repeat 1 (TPR1) and Son of Sevenless (SOS). Cellular Signalling. 22: 1448-58. PMID 20639119 DOI: 10.1016/J.Cellsig.2010.05.013  0.456
2010 Tso PH, Wang Y, Wong SY, Poon LS, Chan AS, Wong YH. RGS19 enhances cell proliferation through its C-terminal PDZ motif. Cellular Signalling. 22: 1700-7. PMID 20599498 DOI: 10.1016/J.Cellsig.2010.06.010  0.406
2010 Yeung WW, Wong YH. Galpha16 interacts with Class IA phosphatidylinositol 3-kinases and inhibits Akt signaling. Cellular Signalling. 22: 1379-87. PMID 20471473 DOI: 10.1016/J.Cellsig.2010.05.008  0.435
2010 Yung HS, Lai KH, Chow KB, Ip NY, Tsim KW, Wong YH, Wu Z, Wise H. Nerve growth factor-induced differentiation of PC12 cells is accompanied by elevated adenylyl cyclase activity. Neuro-Signals. 18: 32-42. PMID 20389133 DOI: 10.1159/000310977  0.422
2010 Yuen JW, Poon LS, Chan AS, Yu FW, Lo RK, Wong YH. Activation of STAT3 by specific Galpha subunits and multiple Gbetagamma dimers. The International Journal of Biochemistry & Cell Biology. 42: 1052-9. PMID 20348012 DOI: 10.1016/J.Biocel.2010.03.017  0.398
2009 Ho MK, Su Y, Yeung WW, Wong YH. Regulation of transcription factors by heterotrimeric G proteins. Current Molecular Pharmacology. 2: 19-31. PMID 20021442 DOI: 10.2174/1874467210902010019  0.427
2009 Lee MM, Wong YH. CCR1-mediated activation of Nuclear Factor-kappaB in THP-1 monocytic cells involves Pertussis Toxin-insensitive Galpha(14) and Galpha(16) signaling cascades. Journal of Leukocyte Biology. 86: 1319-29. PMID 19687291 DOI: 10.1189/Jlb.0209052  0.432
2009 Wang K, Wong YH. G protein signaling controls the differentiation of multiple cell lineages. Biofactors (Oxford, England). 35: 232-8. PMID 19391121 DOI: 10.1002/Biof.39  0.418
2009 Liu AM, New DC, Lo RK, Wong YH. Reporter gene assays. Methods in Molecular Biology (Clifton, N.J.). 486: 109-23. PMID 19347619 DOI: 10.1007/978-1-60327-545-3_8  0.329
2009 Yeung WW, Wong YH. The RhoA-specific guanine nucleotide exchange factor p63RhoGEF binds to activated Galpha(16) and inhibits the canonical phospholipase Cbeta pathway. Cellular Signalling. 21: 1317-25. PMID 19332116 DOI: 10.1016/J.Cellsig.2009.03.017  0.435
2009 Su Y, Ho MK, Wong YH. A hematopoietic perspective on the promiscuity and specificity of Galpha16 signaling. Neuro-Signals. 17: 71-81. PMID 19212141 DOI: 10.1159/000186691  0.388
2009 Ng YP, Wu Z, Wise H, Tsim KW, Wong YH, Ip NY. Differential and synergistic effect of nerve growth factor and cAMP on the regulation of early response genes during neuronal differentiation. Neuro-Signals. 17: 111-20. PMID 19176979 DOI: 10.1159/000197391  0.349
2009 Poon LS, Chan AS, Wong YH. Gbeta3 forms distinct dimers with specific Ggamma subunits and preferentially activates the beta3 isoform of phospholipase C. Cellular Signalling. 21: 737-44. PMID 19168127 DOI: 10.1016/J.Cellsig.2009.01.018  0.361
2009 Chan GP, Wu EH, Wong YH. Regulation of mTOR and p70 S6 kinase by the muscarinic M4 receptor in PC12 cells. Cell Biology International. 33: 230-8. PMID 19070673 DOI: 10.1016/J.Cellbi.2008.11.010  0.423
2009 Tso PH, Morris CJ, Yung LY, Ip NY, Wong YH. Multiple Gi proteins participate in nerve growth factor-induced activation of c-jun N-terminal kinases in PC12 cells Neurochemical Research. 34: 1101-1112. PMID 19009346 DOI: 10.1007/S11064-008-9880-9  0.414
2008 Yu MY, Ho MK, Liu AM, Wong YH. Mutations on the Switch III region and the alpha3 helix of Galpha16 differentially affect receptor coupling and regulation of downstream effectors. Journal of Molecular Signaling. 3: 17. PMID 19025606 DOI: 10.1186/1750-2187-3-17  0.356
2008 Lo RK, Liu AM, Wise H, Wong YH. Prostacyclin receptor-induced STAT3 phosphorylation in human erythroleukemia cells is mediated via Galpha(s) and Galpha(16) hybrid signaling. Cellular Signalling. 20: 2095-106. PMID 18755267 DOI: 10.1016/J.Cellsig.2008.08.003  0.497
2008 Yung LY, Tso PH, Wu EHT, Yu JCH, Ip NY, Wong YH. Nerve growth factor-induced stimulation of p38 mitogen-activated protein kinase in PC12 cells is partially mediated via Gi/o proteins Cellular Signalling. 20: 1538-1544. PMID 18508236 DOI: 10.1016/J.Cellsig.2008.04.007  0.433
2008 Tian Y, Lee MM, Yung LY, Allen RA, Slocombe PM, Twomey BM, Wong YH. Differential involvement of Galpha16 in CC chemokine-induced stimulation of phospholipase Cbeta, ERK, and chemotaxis. Cellular Signalling. 20: 1179-89. PMID 18406577 DOI: 10.1016/J.Cellsig.2008.02.014  0.476
2008 Kwan DH, Kam AY, Wong YH. Activation of the human FPRL-1 receptor promotes Ca2+ mobilization in U87 astrocytoma cells. Neurochemical Research. 33: 125-33. PMID 17703360 DOI: 10.1007/S11064-007-9425-7  0.403
2007 Mody SM, Hu Y, Ho MK, Wong YH. In search of novel and therapeutically significant melatoninergic ligands. Recent Patents On Cns Drug Discovery. 2: 241-5. PMID 18221235 DOI: 10.2174/157488907782411756  0.318
2007 New DC, Wu K, Kwok AW, Wong YH. G protein-coupled receptor-induced Akt activity in cellular proliferation and apoptosis. The Febs Journal. 274: 6025-36. PMID 17949438 DOI: 10.1111/J.1742-4658.2007.06116.X  0.486
2007 Kam AY, Liu AM, Wong YH. Formyl peptide-receptor like-1 requires lipid raft and extracellular signal-regulated protein kinase to activate inhibitor-kappa B kinase in human U87 astrocytoma cells. Journal of Neurochemistry. 103: 1553-66. PMID 17727628 DOI: 10.1111/J.1471-4159.2007.04876.X  0.457
2007 Lok KC, Fu AKY, Ip FCF, Wong YH, Ip NY. NRG induces membrane targeting of Gαz in muscle: Implication in myogenesis Neuroreport. 18: 1433-1436. PMID 17712269 DOI: 10.1097/Wnr.0B013E3282E9A5B7  0.336
2007 Kam AY, Tse TT, Kwan DH, Wong YH. Formyl peptide receptor like 1 differentially requires mitogen-activated protein kinases for the induction of glial fibrillary acidic protein and interleukin-1alpha in human U87 astrocytoma cells. Cellular Signalling. 19: 2106-17. PMID 17643960 DOI: 10.1016/J.Cellsig.2007.06.005  0.482
2007 Lok KC, Fu AKY, Ip FCF, Wong YH, Ip NY. Expression of G protein β subunits in rat skeletal muscle after nerve injury: Implication in the regulation of neuregulin signaling Neuroscience. 146: 594-603. PMID 17368953 DOI: 10.1016/J.Neuroscience.2007.02.007  0.395
2007 New DC, Wong YH. Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progression. Journal of Molecular Signaling. 2: 2. PMID 17319972 DOI: 10.1186/1750-2187-2-2  0.501
2007 Chan AS, Ng LW, Poon LS, Chan WW, Wong YH. Dopaminergic and adrenergic toxicities on SK-N-MC human neuroblastoma cells are mediated through G protein signaling and oxidative stress. Apoptosis : An International Journal On Programmed Cell Death. 12: 167-79. PMID 17136323 DOI: 10.1007/S10495-006-0524-8  0.395
2006 Wu EH, Wu KK, Wong YH. Tuberin: a stimulus-regulated tumor suppressor protein controlled by a diverse array of receptor tyrosine kinases and G protein-coupled receptors. Neuro-Signals. 15: 217-27. PMID 17389815 DOI: 10.1159/000101333  0.448
2006 Liu AM, Lo RK, Wong CS, Morris C, Wise H, Wong YH. Activation of STAT3 by G alpha(s) distinctively requires protein kinase A, JNK, and phosphatidylinositol 3-kinase. The Journal of Biological Chemistry. 281: 35812-25. PMID 17008315 DOI: 10.1074/Jbc.M605288200  0.476
2006 Tso PH, Wong YH. Opioid receptor-like (ORL1) receptor utilizes both G(oA) and G(oB) for signal transduction. Protein and Peptide Letters. 13: 437-41. PMID 16800795 DOI: 10.2174/092986606776819547  0.532
2006 Lo RK, Wong YH. Transcriptional activation of c-Fos by constitutively active Galpha(16)QL through a STAT1-dependent pathway. Cellular Signalling. 18: 2143-53. PMID 16781847 DOI: 10.1016/J.Cellsig.2006.04.004  0.431
2006 Chan AS, Yip EC, Yung LY, Pang H, Luk SC, Pang SF, Wong YH. CKBM stimulates MAPKs but inhibits LPS-induced IFN-gamma in lymphocytes. Phytotherapy Research : Ptr. 20: 725-31. PMID 16775808 DOI: 10.1002/Ptr.1943  0.374
2006 Wu EH, Tam BH, Wong YH. Constitutively active alpha subunits of G(q/11) and G(12/13) families inhibit activation of the pro-survival Akt signaling cascade. The Febs Journal. 273: 2388-98. PMID 16704413 DOI: 10.1111/J.1742-4658.2006.05245.X  0.46
2006 Chan AS, Pang H, Yip EC, Tam YK, Wong YH. The aqueous extract of Radix Glycyrrhizae stimulates mitogen-activated protein kinases and nuclear factor-kappaB in Jurkat T-cells and THP-1 monocytic cells. The American Journal of Chinese Medicine. 34: 263-78. PMID 16552837 DOI: 10.1142/S0192415X06003813  0.406
2006 Yeung PK, Lam CM, Ma ZY, Wong YH, Wong JT. Involvement of calcium mobilization from caffeine-sensitive stores in mechanically induced cell cycle arrest in the dinoflagellate Crypthecodinium cohnii. Cell Calcium. 39: 259-74. PMID 16364435 DOI: 10.1016/J.Ceca.2005.11.001  0.332
2006 New DC, An H, Ip NY, Wong YH. GABAB heterodimeric receptors promote Ca2+ influx via store-operated channels in rat cortical neurons and transfected chinese hamster ovary cells Neuroscience. 137: 1347-1358. PMID 16343781 DOI: 10.1016/J.Neuroscience.2005.10.033  0.408
2006 Lo RK, Wise H, Wong YH. Prostacyclin receptor induces STAT1 and STAT3 phosphorylations in human erythroleukemia cells: a mechanism requiring PTX-insensitive G proteins, ERK and JNK. Cellular Signalling. 18: 307-17. PMID 15979846 DOI: 10.1016/J.Cellsig.2005.05.001  0.476
2006 Wu EH, Wong YH. Activation of muscarinic M4 receptor augments NGF-induced pro-survival Akt signaling in PC12 cells. Cellular Signalling. 18: 285-93. PMID 15979279 DOI: 10.1016/J.Cellsig.2005.04.009  0.47
2006 Yip ECH, Chan ASL, Pang H, Tam YK, Wong YH. Protocatechuic acid induces cell death in HepG2 hepatocellular carcinoma cells through a c-Jun N-terminal kinase-dependent mechanism Cell Biology and Toxicology. 22: 293-302. DOI: 10.1007/S10565-006-9000-Z  0.34
2005 Yip EC, Liu AM, Wong JT, Wong YH. An aqueous extract of the popular Chinese nutraceutical Kwei Ling Ko (Tortoise shell-Rhizome jelly) activates the PPARgamma pathway and down-regulates the NFkappaB activity. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 12: 748-59. PMID 16323294 DOI: 10.1016/J.Phymed.2004.11.002  0.373
2005 Chan AS, Yip EC, Yung LY, Pang H, Luk SC, Pang SF, Wong YH. Immuno-regulatory effects of CKBM on the activities of mitogen-activated protein kinases and the release of cytokines in THP-1 monocytic cells. Biological & Pharmaceutical Bulletin. 28: 1645-50. PMID 16141532 DOI: 10.1248/Bpb.28.1645  0.319
2005 Liu AM, Wong YH. Activation of nuclear factor {kappa}B by somatostatin type 2 receptor in pancreatic acinar AR42J cells involves G{alpha}14 and multiple signaling components: a mechanism requiring protein kinase C, calmodulin-dependent kinase II, ERK, and c-Src. The Journal of Biological Chemistry. 280: 34617-25. PMID 16115892 DOI: 10.1074/Jbc.M504264200  0.498
2005 Liu AM, Wong YH. Mu-opioid receptor-mediated phosphorylation of IkappaB kinase in human neuroblastoma SH-SY5Y cells. Neuro-Signals. 14: 136-42. PMID 16088228 DOI: 10.1159/000086296  0.444
2005 Chan AS, Wong YH. Gq-mediated activation of c-Jun N-terminal kinase by the gastrin-releasing peptide-preferring bombesin receptor is inhibited upon costimulation of the Gs-coupled dopamine D1 receptor in COS-7 cells. Molecular Pharmacology. 68: 1354-64. PMID 16061771 DOI: 10.1124/Mol.105.014548  0.513
2005 Wu EH, Wong YH. Activation of delta-, kappa-, and mu-opioid receptors induces phosphorylation of tuberin in transfected HEK 293 cells and native cells. Biochemical and Biophysical Research Communications. 334: 838-44. PMID 16053916 DOI: 10.1016/J.Bbrc.2005.06.184  0.471
2005 Chan AS, Pang H, Yip EC, Tam YK, Wong YH. Carvacrol and eugenol differentially stimulate intracellular Ca2+ mobilization and mitogen-activated protein kinases in Jurkat T-cells and monocytic THP-1 cells. Planta Medica. 71: 634-9. PMID 16041649 DOI: 10.1055/S-2005-871269  0.4
2005 Chan AS, Yeung WW, Wong YH. Integration of G protein signals by extracellular signal-regulated protein kinases in SK-N-MC neuroepithelioma cells. Journal of Neurochemistry. 94: 1457-70. PMID 15992362 DOI: 10.1111/J.1471-4159.2005.03304.X  0.517
2005 Wu EH, Wong YH. Pertussis toxin-sensitive Gi/o proteins are involved in nerve growth factor-induced pro-survival Akt signaling cascade in PC12 cells. Cellular Signalling. 17: 881-90. PMID 15763430 DOI: 10.1016/J.Cellsig.2004.11.008  0.414
2005 Wu EH, Wong YH. Involvement of G i/o proteins in nerve growth factor-stimulated phosphorylation and degradation of tuberin in PC-12 cells and cortical neurons. Molecular Pharmacology. 67: 1195-205. PMID 15626752 DOI: 10.1124/Mol.104.007237  0.429
2005 New DC, Wong YH. Chimeric and promiscuous G proteins in drug discovery and the deorphanization of GPCRs Drug Design Reviews Online. 2: 66-79. DOI: 10.2174/1567269053390284  0.412
2004 Liu AM, Wong YH. G16-mediated activation of nuclear factor kappaB by the adenosine A1 receptor involves c-Src, protein kinase C, and ERK signaling. The Journal of Biological Chemistry. 279: 53196-204. PMID 15485865 DOI: 10.1074/Jbc.M410196200  0.491
2004 New DC, Wong YH. Characterization of CHO cells stably expressing a G alpha 16/z chimera for high throughput screening of GPCRs. Assay and Drug Development Technologies. 2: 269-80. PMID 15285908 DOI: 10.1089/1540658041410641  0.456
2004 Yuen JW, So IY, Kam AY, Wong YH. Regulation of STAT3 by mu-opioid receptors in human neuroblastoma SH-SY5Y cells. Neuroreport. 15: 1431-5. PMID 15194868 DOI: 10.1097/01.Wnr.0000130433.90962.6E  0.474
2004 Chan AS, Wong YH. Epidermal growth factor differentially augments G(i)-mediated stimulation of c-Jun N-terminal kinase activity. British Journal of Pharmacology. 142: 635-46. PMID 15172963 DOI: 10.1038/Sj.Bjp.0705851  0.513
2004 Lo RK, Wong YH. Signal transducer and activator of transcription 3 activation by the delta-opioid receptor via Galpha14 involves multiple intermediates. Molecular Pharmacology. 65: 1427-39. PMID 15155836 DOI: 10.1124/Mol.65.6.1427  0.496
2004 Chan AS, Wong YH. Gbetagamma signaling and Ca2+ mobilization co-operate synergistically in a Sos and Rac-dependent manner in the activation of JNK by Gq-coupled receptors. Cellular Signalling. 16: 823-36. PMID 15115661 DOI: 10.1016/J.Cellsig.2003.12.007  0.463
2004 Kam AY, Chan AS, Wong YH. Phosphatidylinositol-3 kinase is distinctively required for mu-, but not kappa-opioid receptor-induced activation of c-Jun N-terminal kinase. Journal of Neurochemistry. 89: 391-402. PMID 15056283 DOI: 10.1111/J.1471-4159.2004.02338.X  0.477
2004 Ho MK, Chan JH, Wong CS, Wong YH. Identification of a stretch of six divergent amino acids on the alpha5 helix of Galpha16 as a major determinant of the promiscuity and efficiency of receptor coupling. The Biochemical Journal. 380: 361-9. PMID 15005654 DOI: 10.1042/Bj20040231  0.408
2004 Kam AY, Chan AS, Wong YH. Kappa-opioid receptor signals through Src and focal adhesion kinase to stimulate c-Jun N-terminal kinases in transfected COS-7 cells and human monocytic THP-1 cells. The Journal of Pharmacology and Experimental Therapeutics. 310: 301-10. PMID 14996948 DOI: 10.1124/Jpet.104.065078  0.499
2004 Tian Y, New DC, Yung LY, Allen RA, Slocombe PM, Twomey BM, Lee MM, Wong YH. Differential chemokine activation of CC chemokine receptor 1-regulated pathways: ligand selective activation of Galpha 14-coupled pathways. European Journal of Immunology. 34: 785-95. PMID 14991608 DOI: 10.1002/Eji.200324166  0.516
2004 Chu KM, Chow KB, Wong YH, Wise H. Prostacyclin receptor-mediated activation of extracellular signal-regulated kinases 1 and 2. Cellular Signalling. 16: 477-86. PMID 14709336 DOI: 10.1016/J.Cellsig.2003.09.004  0.506
2004 Hazari A, Lowes V, Chan JH, Wong CS, Ho MK, Wong YH. Replacement of the alpha5 helix of Galpha16 with Galphas-specific sequences enhances promiscuity of Galpha16 toward Gs-coupled receptors. Cellular Signalling. 16: 51-62. PMID 14607275 DOI: 10.1016/S0898-6568(03)00097-4  0.432
2003 Lo RK, Cheung H, Wong YH. Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism. The Journal of Biological Chemistry. 278: 52154-65. PMID 14551213 DOI: 10.1074/Jbc.M307299200  0.461
2003 Chan AS, Law PY, Loh HH, Ho PN, Wu WM, Chan JS, Wong YH. The first and third intracellular loops together with the carboxy terminal tail of the delta-opioid receptor contribute toward functional interaction with Galpha16. Journal of Neurochemistry. 87: 697-708. PMID 14535952 DOI: 10.1046/J.1471-4159.2003.02040.X  0.429
2003 New DC, Wong YH. CC chemokine receptor-coupled signalling pathways. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao Acta Biochimica Et Biophysica Sinica. 35: 779-88. PMID 12958648  0.326
2003 Wong CS, Ho MK, Wong YH. The beta6/alpha5 regions of Galphai2 and GalphaoA increase the promiscuity of Galpha16 but are insufficient for pertussis toxin-catalyzed ADP-ribosylation. European Journal of Pharmacology. 473: 105-15. PMID 12892827 DOI: 10.1016/S0014-2999(03)01975-7  0.376
2003 New DC, Tsim ST, Wong YH. G protein-linked effector and second messenger systems involved in melatonin signal transduction. Neuro-Signals. 12: 59-70. PMID 12876400 DOI: 10.1159/000071815  0.422
2003 Tso PH, Wong YH. Molecular basis of opioid dependence: role of signal regulation by G-proteins. Clinical and Experimental Pharmacology & Physiology. 30: 307-16. PMID 12859419 DOI: 10.1046/J.1440-1681.2003.03835.X  0.447
2003 Liu AM, Ho MK, Wong CS, Chan JH, Pau AH, Wong YH. Galpha(16/z) chimeras efficiently link a wide range of G protein-coupled receptors to calcium mobilization. Journal of Biomolecular Screening. 8: 39-49. PMID 12854997 DOI: 10.1177/1087057102239665  0.43
2003 Wu EH, Lo RK, Wong YH. Regulation of STAT3 activity by G16-coupled receptors. Biochemical and Biophysical Research Communications. 303: 920-5. PMID 12670499 DOI: 10.1016/S0006-291X(03)00451-0  0.511
2003 New DC, Wong YH. BML-190 and AM251 act as inverse agonists at the human cannabinoid CB2 receptor: signalling via cAMP and inositol phosphates. Febs Letters. 536: 157-60. PMID 12586356 DOI: 10.1016/S0014-5793(03)00048-6  0.463
2003 Kam AY, Chan AS, Wong YH. Rac and Cdc42-dependent regulation of c-Jun N-terminal kinases by the delta-opioid receptor. Journal of Neurochemistry. 84: 503-13. PMID 12558970 DOI: 10.1046/J.1471-4159.2003.01535.X  0.495
2003 New DC, Tsim ST, Wong YH. G protein-linked effector and second messenger systems involved in melatonin signal transduction Neurosignals. 12: 59-70. DOI: 10.1159/000071815  0.31
2002 Kam KW, New DC, Wong YH. Constitutive activation of the opioid receptor-like (ORL1) receptor by mutation of Asn133 to tryptophan in the third transmembrane region. Journal of Neurochemistry. 83: 1461-70. PMID 12472900 DOI: 10.1046/J.1471-4159.2002.01231.X  0.502
2002 New DC, Wong YH. The ORL1 receptor: molecular pharmacology and signalling mechanisms. Neuro-Signals. 11: 197-212. PMID 12393946 DOI: 10.1159/000065432  0.473
2002 Simon J, Filippov AK, Göransson S, Wong YH, Frelin C, Michel AD, Brown DA, Barnard EA. Characterization and channel coupling of the P2Y(12) nucleotide receptor of brain capillary endothelial cells. The Journal of Biological Chemistry. 277: 31390-400. PMID 12080041 DOI: 10.1074/Jbc.M110714200  0.425
2002 Ho MK, New DC, Wong YH. Co-expressions of different opioid receptor types differentially modulate their signaling via G(16). Neuro-Signals. 11: 115-22. PMID 12077485 DOI: 10.1159/000058548  0.425
2002 Lai FP, Mody SM, Yung LY, Kam JY, Pang CS, Pang SF, Wong YH. Molecular determinants for the differential coupling of Galpha(16) to the melatonin MT1, MT2 and Xenopus Mel1c receptors. Journal of Neurochemistry. 80: 736-45. PMID 11948236 DOI: 10.1046/J.0022-3042.2002.00767.X  0.455
2002 Wise H, Wong YH, Jones RL. Prostanoid signal integration and cross talk Neurosignals. 11: 20-28. PMID 11943879 DOI: 10.1159/000057318  0.409
2002 Lowes VL, Ip NY, Wong YH. Integration of signals from receptor tyrosine kinases and G protein-coupled receptors Neurosignals. 11: 5-19. PMID 11943878 DOI: 10.1159/000057317  0.433
2002 Chan AS, Lai FP, Lo RK, Voyno-Yasenetskaya TA, Stanbridge EJ, Wong YH. Melatonin mt1 and MT2 receptors stimulate c-Jun N-terminal kinase via pertussis toxin-sensitive and -insensitive G proteins. Cellular Signalling. 14: 249-57. PMID 11812653 DOI: 10.1016/S0898-6568(01)00240-6  0.533
2002 Lee JWM, Joshi S, Chan JSC, Wong YH. Differential Coupling of μ‐, δ‐, and κ‐Opioid Receptors to Gα16‐Mediated Stimulation of Phospholipase C Journal of Neurochemistry. 70: 2203-2211. DOI: 10.1046/J.1471-4159.1998.70052203.X  0.469
2001 Chow KBS, Wong YH, Wise H. Prostacyclin receptor-independent inhibition of phospholipase C activity by non-prostanoid prostacyclin mimetics British Journal of Pharmacology. 134: 1375-1384. PMID 11724742 DOI: 10.1038/Sj.Bjp.0704388  0.451
2001 Tso PH, Wong YH. Role of extracellular signal-regulated kinases in opioid-induced adenylyl cyclase superactivation in human embryonic kidney 293 cells Neuroscience Letters. 316: 13-16. PMID 11720767 DOI: 10.1016/S0304-3940(01)02340-0  0.43
2001 Miller-Martini DM, Chan RYK, Ip NY, Sheu SJ, Wong YH. A reporter gene assay for the detection of phytoestrogens in traditional Chinese medicine Phytotherapy Research. 15: 487-492. PMID 11536376 DOI: 10.1002/Ptr.767  0.35
2001 Lai FPL, Mody SM, Yung LY, Pang CS, Pang SF, Wong YH. Chimeric Galphaq subunits can distinguish the long form of the Xenopus Mel1c melatonin receptor from the mammalian mt1 and MT2 melatonin receptors. Journal of Pineal Research. 30: 171-179. PMID 11316328 DOI: 10.1034/J.1600-079X.2001.300306.X  0.433
2001 Ho MK, Wong YH. G(z) signaling: emerging divergence from G(i) signaling. Oncogene. 20: 1615-25. PMID 11313909 DOI: 10.1038/Sj.Onc.1204190  0.486
2001 Choi RC, Siow NL, Zhu SQ, Wan DC, Wong YH, Tsim KW. The cyclic AMP-mediated expression of acetylcholinesterase in myotubes shows contrasting activation and repression between avian and mammalian enzymes. Molecular and Cellular Neurosciences. 17: 732-45. PMID 11312608 DOI: 10.1006/Mcne.2001.0968  0.387
2001 Ho MK, Yung LY, Chan JS, Chan JH, Wong CS, Wong YH. Galpha(14) links a variety of G(i)- and G(s)-coupled receptors to the stimulation of phospholipase C. British Journal of Pharmacology. 132: 1431-40. PMID 11264236 DOI: 10.1038/Sj.Bjp.0703933  0.493
2001 Yip EC, Wong YH, Wong JT. Bacterial formyl peptide mediated chemotaxis and extracellular acidification in shrimp haemocytes. Developmental and Comparative Immunology. 25: 269-77. PMID 11246066 DOI: 10.1016/S0145-305X(00)00060-4  0.344
2001 Tso PH, Wong YH. Opioid-induced adenylyl cyclase supersensitization in human embryonic kidney 293 cells requires pertussis toxin-sensitive G proteins other than Gi1 and Gi3 Neuroscience Letters. 299: 25-28. PMID 11166929 DOI: 10.1016/S0304-3940(00)01772-9  0.422
2000 Chan ASL, Wong YH. Regulation of c-Jun N-terminal Kinase by the ORL1 receptor through multiple G proteins Journal of Pharmacology and Experimental Therapeutics. 295: 1094-1100. PMID 11082445  0.448
2000 Ho MK, Wong YH. The amino terminus of Galpha(z) is required for receptor recognition, whereas its alpha4/beta6 loop is essential for inhibition of adenylyl cyclase. Molecular Pharmacology. 58: 993-1000. PMID 11040046 DOI: 10.1124/Mol.58.5.993  0.44
2000 Tso PH, Wong YH. G(z) can mediate the acute actions of μ- and κ-opioids but is not involved in opioid-induced adenylyl cyclase supersensitization Journal of Pharmacology and Experimental Therapeutics. 295: 168-176. PMID 10991975  0.337
2000 Belcheva MM, Wong YH, Coscia CJ. Evidence for transduction of mu but not kappa opioid modulation of extracellular signal-regulated kinase activity by G(z) and G(12) proteins. Cellular Signalling. 12: 481-9. PMID 10989284 DOI: 10.1016/S0898-6568(00)00095-4  0.451
2000 Yung LY, Tsim KW, Pei G, Wong YH. Immunoglobulin G1 Fc fragment-tagged human opioid receptor-like receptor retains the ability to inhibit cAMP accumulation. Biological Signals and Receptors. 9: 240-7. PMID 10965058 DOI: 10.1159/000014645  0.452
2000 Law PY, Wong YH, Loh HH. Molecular mechanisms and regulation of opioid receptor signaling. Annual Review of Pharmacology and Toxicology. 40: 389-430. PMID 10836142 DOI: 10.1146/Annurev.Pharmtox.40.1.389  0.436
2000 New DC, Wong YH, Wong JT. Cloning of a novel G-protein-coupled receptor from the sea anemone nervous system. Biochemical and Biophysical Research Communications. 271: 761-9. PMID 10814536 DOI: 10.1006/Bbrc.2000.2660  0.443
2000 Antonelli V, Bernasconi F, Wong YH, Vallar L. Activation of B-Raf and regulation of the mitogen-activated protein kinase pathway by the G(o) alpha chain. Molecular Biology of the Cell. 11: 1129-42. PMID 10749919 DOI: 10.1091/MBC.11.4.1129  0.364
2000 Tso PH, Yung LY, Wong YH. Regulation of adenylyl cyclase, ERK1/2, and CREB by G(z) following acute and chronic activation of the δ-opioid receptor Journal of Neurochemistry. 74: 1685-1693. PMID 10737627 DOI: 10.1046/J.1471-4159.2000.0741685.X  0.479
2000 Chan JS, Lee JW, Ho MK, Wong YH. Preactivation permits subsequent stimulation of phospholipase C by G(i)-coupled receptors. Molecular Pharmacology. 57: 700-8. PMID 10727515 DOI: 10.1124/Mol.57.4.700  0.532
2000 Ho MK, Chan JS, Yung LY, Wong YH. The effect of protein kinase C activation on G(z)-mediated regulation of type 2 and 6 adenylyl cyclases. Biological Signals and Receptors. 9: 21-8. PMID 10686433 DOI: 10.1159/000014619  0.439
2000 Xu RK, Wu XM, Di AK, Xu JN, Pang CS, Pang SF, Meng Z, Lu G, Wang Q, Wu Y, Aerts T, Slegers H, Clauwaert J, Ho MKC, Chan JSC, ... ... Wong YH, et al. Receptor and Non-Receptor Mediated Actions of Melatonin Neurosignals. 9: 53-75. DOI: 10.1159/000014623  0.401
2000 Tso PH, Wong YH. Deciphering the role of G(i2) in opioid-induced adenylyl cyclase supersensitization Neuroreport. 11: 3213-3217. DOI: 10.1097/00001756-200009280-00033  0.452
1999 Law PY, Wong YH, Loh HH. Mutational analysis of the structure and function of opioid receptors. Biopolymers. 51: 440-55. PMID 10797232 DOI: 10.1002/(Sici)1097-0282(1999)51:6<440::Aid-Bip6>3.0.Co;2-T  0.419
1999 Chan RYK, Wong YH. Chronic activation of ORL1 receptor induces supersensitization of adenylyl cyclase. Neuroreport. 10: 2901-2905. PMID 10549794 DOI: 10.1097/00001756-199909290-00005  0.489
1999 Joshi S, Lee JWM, Wong YH. Stimulation of phospholipase C by the cloned μ, δ and κ opioid receptors via chimeric Gα(q) mutants European Journal of Neuroscience. 11: 383-388. PMID 10051738 DOI: 10.1046/J.1460-9568.1999.00442.X  0.452
1999 Chan RYK, Wong YH. Chronic activation of ORL 1 receptor induces supersensitization of adenylyl cyclase Neuroreport. 10: 2901-2905.  0.392
1998 Li L, Xu JN, Wong YH, Wong JT, Pang SF, Shiu SY. Molecular and cellular analyses of melatonin receptor-mediated cAMP signaling in rat corpus epididymis. Journal of Pineal Research. 25: 219-28. PMID 9885991 DOI: 10.1111/J.1600-079X.1998.Tb00391.X  0.447
1998 Joshi SA, Fan KP, Ho VW, Wong YH. Chimeric Galpha(q) mutants harboring the last five carboxy-terminal residues of Galpha(i2) or Galpha(o) are resistant to pertussis toxin-catalyzed ADP-ribosylation. Febs Letters. 441: 67-70. PMID 9877167 DOI: 10.1016/S0014-5793(98)01527-0  0.411
1998 Chan JS, Yung LY, Lee JW, Wu YL, Pei G, Wong YH. Pertussis toxin-insensitive signaling of the ORL1 receptor: coupling to Gz and G16 proteins. Journal of Neurochemistry. 71: 2203-10. PMID 9798948 DOI: 10.1046/J.1471-4159.1998.71052203.X  0.51
1998 Choi RC, Yung LY, Dong TT, Wan DC, Wong YH, Tsim KW. The calcitonin gene-related peptide-induced acetylcholinesterase synthesis in cultured chick myotubes is mediated by cyclic AMP. Journal of Neurochemistry. 71: 152-60. PMID 9648861 DOI: 10.1046/J.1471-4159.1998.71010152.X  0.382
1998 Tsim ST, Wong JT, Wong YH. Regulation of calcium influx and phospholipase C activity by indoleamines in dinoflagellate Crypthecodinium cohnii. Journal of Pineal Research. 24: 152-61. PMID 9551852 DOI: 10.1111/J.1600-079X.1998.Tb00528.X  0.309
1997 Tsu RC, Ho MK, Yung LY, Joshi S, Wong YH. Role of amino- and carboxyl-terminal regions of G(alphaZ) in the recognition of Gi-coupled receptors. Molecular Pharmacology. 52: 38-45. PMID 9224810 DOI: 10.1124/Mol.52.1.38  0.409
1997 Ho MK, Wong YH. Functional role of amino-terminal serine16 and serine27 of G alphaZ in receptor and effector coupling. Journal of Neurochemistry. 68: 2514-22. PMID 9166747 DOI: 10.1046/J.1471-4159.1997.68062514.X  0.392
1997 Beck HI, Chan JS, Wong YH. Receptor-induced beta gamma release from fatty acylation-deficient mutants of G alpha z. Neuroreport. 8: 937-40. PMID 9141068 DOI: 10.1097/00001756-199703030-00024  0.342
1997 Beck HI, Chan JSC, Wong YH. Receptor-induced by release from fatty acylation-deficient mutants of Gα(z) Neuroreport. 8: 937-940.  0.312
1996 Chiu TT, Yung LY, Wong YH. Inverse agonistic effect of ICI-174,864 on the cloned delta-opioid receptor: role of G protein and adenylyl cyclase activation. Molecular Pharmacology. 50: 1651-7. PMID 8967989  0.38
1996 Tslm ST, Wong JT, Wong YH. CGP 52608-induced cyst formation in dinoflagellates: possible involvement of a nuclear receptor for melatonin. Journal of Pineal Research. 21: 101-7. PMID 8912235 DOI: 10.1111/J.1600-079X.1996.Tb00276.X  0.5
1996 Tsu RC, Wong YH. Gi-mediated stimulation of type II adenylyl cyclase is augmented by Gq-coupled receptor activation and phorbol ester treatment Journal of Neuroscience. 16: 1317-1323. PMID 8778283 DOI: 10.1523/Jneurosci.16-04-01317.1996  0.484
1996 Wong YH. The G protein linkage of melatonin receptors Frontiers of Hormone Research. 21: 147-153.  0.318
1996 Tsim ST, Wong JTY, Wong YH. CGP 52608-induced cyst formation in dinoflagellates: Possible involvement of a nuclear receptor for melatonin Journal of Pineal Research. 21: 101-107.  0.406
1995 Shum JK, Allen RA, Wong YH. The human chemoattractant complement C5a receptor inhibits cyclic AMP accumulation through Gi and Gz proteins. Biochemical and Biophysical Research Communications. 208: 223-9. PMID 7887933 DOI: 10.1006/Bbrc.1995.1327  0.447
1995 Lai HWL, Minami M, Satoh M, Wong YH. GZ coupling to the rat κ-opioid receptor Febs Letters. 360: 97-99. PMID 7875310 DOI: 10.1016/0014-5793(95)00088-Q  0.444
1995 Tsu RC, Chan JS, Wong YH. Regulation of multiple effectors by the cloned delta-opioid receptor: stimulation of phospholipase C and type II adenylyl cyclase. Journal of Neurochemistry. 64: 2700-7. PMID 7760050 DOI: 10.1046/J.1471-4159.1995.64062700.X  0.451
1995 Tsu RC, Lai HWL, Allen RA, Wong YH. Differential coupling of the formyl peptide receptor to adenylate cyclase and phospholipase C by the pertussis toxin-insensitive G(Z) protein Biochemical Journal. 309: 331-339. PMID 7619076 DOI: 10.1042/Bj3090331  0.515
1995 Chan JS, Chiu TT, Wong YH. Activation of type II adenylyl cyclase by the cloned mu-opioid receptor: coupling to multiple G proteins. Journal of Neurochemistry. 65: 2682-9. PMID 7595566 DOI: 10.1046/J.1471-4159.1995.65062682.X  0.456
1995 Yung LY, Tsim ST, Wong YH. Stimulation of cAMP accumulation by the cloned Xenopus melatonin receptor through Gi and Gz proteins Febs Letters. 372: 99-102. PMID 7556653 DOI: 10.1016/0014-5793(95)00963-A  0.498
1992 Wong YH, Conklin BR, Bourne HR. Gz-mediated hormonal inhibition of cyclic AMP accumulation. Science (New York, N.Y.). 255: 339-42. PMID 1347957 DOI: 10.1126/Science.1347957  0.386
1992 Bourne HR, Lustig KD, Wong YH, Conklin BR. Detection of coincident signals by G proteins and adenylyl cyclase. Cold Spring Harbor Symposia On Quantitative Biology. 57: 145-8. PMID 1339653 DOI: 10.1101/Sqb.1992.057.01.018  0.359
1991 Wong YH, Federman A, Pace AM, Zachary I, Evans T, Pouysségur J, Bourne HR. Mutant alpha subunits of Gi2 inhibit cyclic AMP accumulation. Nature. 351: 63-5. PMID 1851251 DOI: 10.1038/351063A0  0.306
1991 Pace AM, Wong YH, Bourne HR. A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 7031-5. PMID 1651490 DOI: 10.1073/Pnas.88.16.7031  0.315
1990 Wong YH, Demoliou-Mason CD, Hanley MR, Barnard EA. Agonist-selective protection of the opioid receptor-coupled G proteins from inactivation by 5'-p-fluorosulphonylbenzoyl guanosine. Journal of Neurochemistry. 54: 39-45. PMID 2152798 DOI: 10.1111/J.1471-4159.1990.Tb13280.X  0.429
1989 Wong YH, Demoliou-Mason CD, Barnard EA. Opioid receptors in magnesium-digitonin-solubilized rat brain membranes are tightly coupled to a pertussis toxin-sensitive guanine nucleotide-binding protein. Journal of Neurochemistry. 52: 999-1009. PMID 2538569 DOI: 10.1111/J.1471-4159.1989.Tb01840.X  0.427
1988 Wong YH, Demoliou-Mason CD, Barnard EA. ADP-ribosylation with pertussis toxin modulates the GTP-sensitive opioid ligand binding in digitonin-soluble extracts of rat brain membranes. Journal of Neurochemistry. 51: 114-21. PMID 2837532 DOI: 10.1111/J.1471-4159.1988.Tb04843.X  0.372
1987 Jackson TR, Patterson SI, Wong YH, Hanley MR. Bradykinin stimulation of inositol phosphate and calcium responses in insensitive to pertussis toxin in NG115-401L neuronal cells. Biochemical and Biophysical Research Communications. 148: 412-6. PMID 2823811 DOI: 10.1016/0006-291X(87)91126-0  0.372
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