Mati Fridkin - Publications

Affiliations: 
ORG Organic Chemistry Weizmann Institute of Science, Rehovot, Israel 
Area:
Organic Chemistry, Pharmacy, Oncology

206 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cooper I, Atrakchi D, Walker MD, Horovitz A, Fridkin M, Shechter Y. Converting bleomycin into a prodrug that undergoes spontaneous reactivation under physiological conditions. Toxicology and Applied Pharmacology. 114782. PMID 31655077 DOI: 10.1016/J.Taap.2019.114782  0.327
2016 Cooper I, Fridkin M, Shechter Y. Conjugation of Methotrexate-Amino Derivatives to Macromolecules through Carboxylate Moieties Is Superior Over Conventional Linkage to Amino Residues: Chemical, Cell-Free and In Vitro Characterizations. Plos One. 11: e0158352. PMID 27403959 DOI: 10.1371/Journal.Pone.0158352  0.356
2012 Cooper I, Sasson K, Teichberg VI, Schnaider-Beeri M, Fridkin M, Shechter Y. Peptide derived from HIV-1 TAT protein destabilizes a monolayer of endothelial cells in an in vitro model of the blood-brain barrier and allows permeation of high molecular weight proteins. The Journal of Biological Chemistry. 287: 44676-83. PMID 23150670 DOI: 10.1074/Jbc.M112.395384  0.379
2012 Shechter Y, Sasson K, Marcus Y, Rubinraut S, Lev-Goldman V, Fridkin M. Establishing the principle of reversibility in peptide/protein and small-molecule therapy. Therapeutic Delivery. 3: 17-23. PMID 22833930 DOI: 10.4155/Tde.11.133  0.769
2012 Shechter Y, Sasson K, Lev-Goldman V, Rubinraut S, Rubinstein M, Fridkin M. Newly designed modifier prolongs the action of short-lived peptides and proteins by allowing their binding to serum albumin. Bioconjugate Chemistry. 23: 1577-86. PMID 22759320 DOI: 10.1021/Bc3000854  0.785
2012 Zheng H, Amit T, Bar-Am O, Fridkin M, Youdim MB, Mandel SA. From anti-Parkinson's drug rasagiline to novel multitarget iron chelators with acetylcholinesterase and monoamine oxidase inhibitory and neuroprotective properties for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 30: 1-16. PMID 22387411 DOI: 10.3233/Jad-2012-120013  0.335
2011 Blank M, Baraam L, Eisenstein M, Fridkin M, Dardik R, Heldman Y, Katchalski-Katzir E, Shoenfeld Y. β2-Glycoprotein-I based peptide regulate endothelial-cells tissue-factor expression via negative regulation of pGSK3β expression and reduces experimental-antiphospholipid-syndrome. Journal of Autoimmunity. 37: 8-17. PMID 21524885 DOI: 10.1016/J.Jaut.2011.02.008  0.35
2010 Zheng H, Youdim MB, Fridkin M. Selective acetylcholinesterase inhibitor activated by acetylcholinesterase releases an active chelator with neurorescuing and anti-amyloid activities. Acs Chemical Neuroscience. 1: 737-46. PMID 22778810 DOI: 10.1021/Cn100069C  0.317
2010 Zheng H, Fridkin M, Youdim MB. Site-activated chelators derived from anti-Parkinson drug rasagiline as a potential safer and more effective approach to the treatment of Alzheimer's disease. Neurochemical Research. 35: 2117-23. PMID 20981484 DOI: 10.1007/S11064-010-0293-1  0.324
2010 Zheng H, Youdim MB, Fridkin M. Site-activated chelators targeting acetylcholinesterase and monoamine oxidase for Alzheimer's therapy. Acs Chemical Biology. 5: 603-10. PMID 20455574 DOI: 10.1021/Cb900264W  0.303
2010 Rubin N, Perugia E, Wolf SG, Klein E, Fridkin M, Addadi L. Relation between serum amyloid A truncated peptides and their suprastructure chirality. Journal of the American Chemical Society. 132: 4242-8. PMID 20218685 DOI: 10.1021/Ja909345P  0.762
2010 Sasson K, Marcus Y, Lev-Goldman V, Rubinraut S, Fridkin M, Shechter Y. Engineering prolonged-acting prodrugs employing an albumin-binding probe that undergoes slow hydrolysis at physiological conditions. Journal of Controlled Release : Official Journal of the Controlled Release Society. 142: 214-20. PMID 19883707 DOI: 10.1016/J.Jconrel.2009.10.028  0.769
2009 Zheng H, Youdim MB, Fridkin M. Site-activated multifunctional chelator with acetylcholinesterase and neuroprotective-neurorestorative moieties for Alzheimer's therapy. Journal of Medicinal Chemistry. 52: 4095-8. PMID 19485411 DOI: 10.1021/Jm900504C  0.307
2009 Kasher R, Bajayo A, Gabet Y, Nevo N, Fridkin M, Katchalski-Katzir E, Kohen F, Bab I. Restrain of bone growth by estrogen-mimetic peptide-1 (EMP-1): a micro-computed tomographic study. Peptides. 30: 1181-6. PMID 19463753 DOI: 10.1016/J.Peptides.2009.02.019  0.328
2009 Perugia E, Monticelli E, Rubinraut S, Kapitkovsky A, Fridkin M. The amyloidogenic domains of the human serum amyloid A protein--new insights. Advances in Experimental Medicine and Biology. 611: 69-70. PMID 19400097 DOI: 10.1007/978-0-387-73657-0_30  0.76
2008 Marcus Y, Sasson K, Fridkin M, Shechter Y. Turning low-molecular-weight drugs into prolonged acting prodrugs by reversible pegylation: a study with gentamicin. Journal of Medicinal Chemistry. 51: 4300-5. PMID 18578475 DOI: 10.1021/Jm8002558  0.316
2008 Lev-Goldman V, Mester B, Ben-Aroya N, Hanoch T, Rupp B, Stanoeva T, Gescheidt G, Seger R, Koch Y, Weiner L, Fridkin M. Conjugates of gonadotropin releasing hormone (GnRH) with carminic acid: Synthesis, generation of reactive oxygen species (ROS) and biological evaluation. Bioorganic & Medicinal Chemistry. 16: 6789-98. PMID 18571926 DOI: 10.1016/J.Bmc.2008.05.057  0.758
2008 Rubin N, Perugia E, Goldschmidt M, Fridkin M, Addadi L. Chirality of amyloid suprastructures. Journal of the American Chemical Society. 130: 4602-3. PMID 18338897 DOI: 10.1021/Ja800328Y  0.754
2008 Blat D, Weiner L, Youdim MB, Fridkin M. A Novel iron-chelating derivative of the neuroprotective peptide NAPVSIPQ shows superior antioxidant and antineurodegenerative capabilities. Journal of Medicinal Chemistry. 51: 126-34. PMID 18078312 DOI: 10.1021/Jm070800L  0.361
2008 Nesher M, Vachutinsky Y, Fridkin G, Schwarz Y, Sasson K, Fridkin M, Shechter Y, Lichtstein D. Reversible pegylation prolongs the hypotensive effect of atrial natriuretic peptide. Bioconjugate Chemistry. 19: 342-8. PMID 18069777 DOI: 10.1021/Bc700294W  0.432
2008 Dangoor D, Biondi B, Gobbo M, Vachutinski Y, Fridkin M, Gozes I, Rocchi R. Novel glycosylated VIP analogs: synthesis, biological activity, and metabolic stability. Journal of Peptide Science : An Official Publication of the European Peptide Society. 14: 321-8. PMID 17924396 DOI: 10.1002/Psc.932  0.421
2007 Avramovich-Tirosh Y, Reznichenko L, Mit T, Zheng H, Fridkin M, Weinreb O, Mandel S, Youdim MB. Neurorescue activity, APP regulation and amyloid-beta peptide reduction by novel multi-functional brain permeable iron- chelating- antioxidants, M-30 and green tea polyphenol, EGCG. Current Alzheimer Research. 4: 403-11. PMID 17908043 DOI: 10.2174/156720507781788927  0.34
2007 Dangoor D, Rubinraut S, Fridkin M, Gozes I. Novel analogs of VIP with multiple C-terminal domains. Peptides. 28: 1622-30. PMID 17481779 DOI: 10.1016/J.Peptides.2007.03.014  0.359
2007 Avramovich-Tirosh Y, Amit T, Bar-Am O, Zheng H, Fridkin M, Youdim MB. Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator-monoamine oxidase inhibitor drug, M-30, for the treatment of Alzheimer's disease. Journal of Neurochemistry. 100: 490-502. PMID 17144902 DOI: 10.1111/J.1471-4159.2006.04258.X  0.329
2007 Shechter Y, Mironchik M, Saul A, Gershonov E, Precido-Patt L, Sasson K, Tsubery H, Mester B, Kapitkovsky A, Rubinraut S, Vachutinski Y, Fridkin G, Fridkin M. New technologies to prolong life-time of peptide and protein drugs in vivo International Journal of Peptide Research and Therapeutics. 13: 105-117. DOI: 10.1007/S10989-006-9052-1  0.385
2006 Burov SV, Iablokova TV, Dorosh MIu, Shkarubskaia ZP, Blank M, EpshteÄ­n N, Fridkin M. [Luliberin analogues exhibiting a cytotoxic effect on tumor cells in vitro]. Bioorganicheskaia Khimiia. 32: 459-66. PMID 17042263 DOI: 10.1134/S1068162006050037  0.367
2006 Dangoor D, Rubinraut S, Fridkin M, Gozes I. Novel extended and branched N-terminal analogs of VIP. Regulatory Peptides. 137: 42-9. PMID 16962672 DOI: 10.1016/J.Regpep.2006.02.010  0.387
2006 Lev-Goldman V, Mester B, Ben-Aroya N, Koch Y, Weiner L, Fridkin M. Synthesis and active oxygen generation by new emodin derivatives and their gonadotropin-releasing hormone conjugates. Bioconjugate Chemistry. 17: 1008-16. PMID 16848409 DOI: 10.1021/Bc050293R  0.769
2006 Husebye ES, Bratland E, Bredholt G, Fridkin M, Dayan M, Mozes E. The substrate-binding domain of 21-hydroxylase, the main autoantigen in autoimmune Addison's disease, is an immunodominant T cell epitope. Endocrinology. 147: 2411-6. PMID 16497795 DOI: 10.1210/En.2006-0018  0.347
2006 Fridkin G, Rahimipour S, Ben-Aroya N, Kapitkovsky A, Di-Segni S, Rosenberg M, Kustanovich I, Koch Y, Gilon C, Fridkin M. Novel cyclic azo-bridged analogs of gonadotropin-releasing hormone. Journal of Peptide Science : An Official Publication of the European Peptide Society. 12: 106-15. PMID 16059965 DOI: 10.1002/Psc.696  0.425
2005 Tsubery H, Yaakov H, Cohen S, Giterman T, Matityahou A, Fridkin M, Ofek I. Neopeptide antibiotics that function as opsonins and membrane-permeabilizing agents for gram-negative bacteria. Antimicrobial Agents and Chemotherapy. 49: 3122-8. PMID 16048913 DOI: 10.1128/Aac.49.8.3122-3128.2005  0.347
2005 Shechter Y, Mironchik M, Rubinraut S, Saul A, Tsubery H, Fridkin M. Albumin-insulin conjugate releasing insulin slowly under physiological conditions: a new concept for long-acting insulin. Bioconjugate Chemistry. 16: 913-20. PMID 16029032 DOI: 10.1021/Bc050055W  0.302
2005 Dangoor D, Giladi E, Fridkin M, Gozes I. Neuropeptide receptor transcripts are expressed in the rat clitoris and oscillate during the estrus cycle in the rat vagina. Peptides. 26: 2579-84. PMID 16023261 DOI: 10.1016/J.Peptides.2005.06.005  0.303
2005 Shacham S, Cheifetz MN, Fridkin M, Pawson AJ, Millar RP, Naor Z. Identification of Ser153 in ICL2 of the gonadotropin-releasing hormone (GnRH) receptor as a phosphorylation-independent site for inhibition of Gq coupling. The Journal of Biological Chemistry. 280: 28981-8. PMID 15964850 DOI: 10.1074/Jbc.M500312200  0.423
2005 Shechter Y, Tsubery H, Mironchik M, Rubinstein M, Fridkin M. Reversible PEGylation of peptide YY3-36 prolongs its inhibition of food intake in mice. Febs Letters. 579: 2439-44. PMID 15848185 DOI: 10.1016/J.Febslet.2005.03.044  0.362
2005 Di-Segni S, Giordano C, Rahimipour S, Ben-Aroya N, Koch Y, Fridkin M. beta-Sulfonamido gonadotropin-releasing hormone analogs: synthesis and evaluation of several parent hormone properties. Journal of Peptide Science : An Official Publication of the European Peptide Society. 11: 45-52. PMID 15635726 DOI: 10.1002/Psc.596  0.395
2005 Fridkin M, Tsubery H, Tzehoval E, Vonsover A, Biondi L, Filira F, Rocchi R. Tuftsin-AZT conjugate: potential macrophage targeting for AIDS therapy. Journal of Peptide Science : An Official Publication of the European Peptide Society. 11: 37-44. PMID 15635725 DOI: 10.1002/Psc.587  0.359
2004 Kasher R, Gayer B, Kulik T, Somjen D, Venkatesh N, Fridkin M, Katchalski-Katzir E, Kohen F. Design, synthesis, and evaluation of peptides with estrogen-like activity. Biopolymers. 76: 404-20. PMID 15468062 DOI: 10.1002/Bip.20133  0.408
2004 Barda Y, Cohen N, Lev V, Ben-Aroya N, Koch Y, Mishani E, Fridkin M, Gilon C. Backbone metal cyclization: novel 99mTc labeled GnRH analog as potential SPECT molecular imaging agent in cancer. Nuclear Medicine and Biology. 31: 921-33. PMID 15464394 DOI: 10.1016/J.Nucmedbio.2004.05.003  0.33
2004 Peleg-Shulman T, Tsubery H, Mironchik M, Fridkin M, Schreiber G, Shechter Y. Reversible PEGylation: a novel technology to release native interferon alpha2 over a prolonged time period. Journal of Medicinal Chemistry. 47: 4897-904. PMID 15369394 DOI: 10.1021/Jm0497693  0.373
2004 Tsubery H, Mironchik M, Fridkin M, Shechter Y. Prolonging the action of protein and peptide drugs by a novel approach of reversible polyethylene glycol modification. The Journal of Biological Chemistry. 279: 38118-24. PMID 15190059 DOI: 10.1074/Jbc.M405155200  0.424
2004 Pierangeli SS, Blank M, Liu X, Espinola R, Fridkin M, Ostertag MV, Roye-Green K, Harris EN, Shoenfeld Y. A peptide that shares similarity with bacterial antigens reverses thrombogenic properties of antiphospholipid antibodies in vivo. Journal of Autoimmunity. 22: 217-25. PMID 15041042 DOI: 10.1016/J.Jaut.2004.01.002  0.414
2003 Fuchs S, Kasher R, Balass M, Scherf T, Harel M, Fridkin M, Sussman JL, Katchalski-Katzir E. The binding site of acetylcholine receptor: from synthetic peptides to solution and crystal structure. Annals of the New York Academy of Sciences. 998: 93-100. PMID 14592866 DOI: 10.1196/Annals.1254.011  0.358
2003 Gozes I, Divinsky I, Pilzer I, Fridkin M, Brenneman DE, Spier AD. From Vasoactive Intestinal Peptide (VIP) Through Activity-Dependent Neuroprotective Protein (ADNP) to NAP: A View of Neuroprotection and Cell Division Journal of Molecular Neuroscience. 20: 315-322. PMID 14501014 DOI: 10.1385/Jmn:20:3:315  0.418
2003 Rahimipour S, Ben-Aroya N, Ziv K, Chen A, Fridkin M, Koch Y. Receptor-mediated targeting of a photosensitizer by its conjugation to gonadotropin-releasing hormone analogues. Journal of Medicinal Chemistry. 46: 3965-74. PMID 12954050 DOI: 10.1021/Jm020535Y  0.367
2003 Katz M, Tsubery H, Kolusheva S, Shames A, Fridkin M, Jelinek R. Lipid binding and membrane penetration of polymyxin B derivatives studied in a biomimetic vesicle system. The Biochemical Journal. 375: 405-13. PMID 12848621 DOI: 10.1042/Bj20030784  0.356
2003 Shechter Y, Tsubery H, Fridkin M. [2-Sulfo-9-fluorenylmethoxycarbonyl]3-exendin-4-a long-acting glucose-lowering prodrug. Biochemical and Biophysical Research Communications. 305: 386-91. PMID 12745087 DOI: 10.1016/S0006-291X(03)00715-0  0.364
2003 Katchalski-Katzir E, Kasher R, Balass M, Scherf T, Harel M, Fridkin M, Sussman JL, Fuchs S. Design and synthesis of peptides that bind alpha-bungarotoxin with high affinity and mimic the three-dimensional structure of the binding-site of acetylcholine receptor. Biophysical Chemistry. 100: 293-305. PMID 12646372 DOI: 10.1016/S0301-4622(02)00287-9  0.346
2002 Tsubery H, Ofek I, Cohen S, Eisenstein M, Fridkin M. Modulation of the hydrophobic domain of polymyxin B nonapeptide: effect on outer-membrane permeabilization and lipopolysaccharide neutralization. Molecular Pharmacology. 62: 1036-42. PMID 12391265 DOI: 10.1124/Mol.62.5.1036  0.319
2002 Wollman Y, Blumberg S, Spungin A, Brenneman DE, Fridkin M, Wollman J, Iaina A, Gozes I. The increased proliferation of cultured neuroblastoma cells treated with vasoactive intestinal peptide is enhanced by simultaneous inhibition of neutral endopeptidase Regulatory Peptides. 108: 175-177. PMID 12220742 DOI: 10.1016/S0167-0115(02)00098-8  0.364
2002 Shechter Y, Tsubery H, Fridkin M. N-[(2-Sulfo)-9-fluorenylmethoxycarbonyl](3)-gentamicin C(1) is a long-acting prodrug derivative. Journal of Medicinal Chemistry. 45: 4264-70. PMID 12213067 DOI: 10.1021/Jm020042T  0.318
2002 Carmon L, Bobilev-Priel I, Brenner B, Bobilev D, Paz A, Bar-Haim E, Tirosh B, Klein T, Fridkin M, Lemonnier F, Tzehoval E, Eisenbach L. Characterization of novel breast carcinoma-associated BA46-derived peptides in HLA-A2.1/D(b)-beta2m transgenic mice. The Journal of Clinical Investigation. 110: 453-62. PMID 12189239 DOI: 10.1172/Jci14071  0.36
2002 Leker RR, Teichner A, Grigoriadis N, Ovadia H, Brenneman DE, Fridkin M, Giladi E, Romano J, Gozes I. NAP, a femtomolar-acting peptide, protects the brain against ischemic injury by reducing apoptotic death Stroke. 33: 1085-1092. PMID 11935065 DOI: 10.1161/01.Str.0000014207.05597.D7  0.321
2002 Moody TW, Jensen RT, Fridkin M, Gozes I. (N-stearyl, Norleucine17)VIPhybrid is a broad spectrum vasoactive intestinal peptide receptor antagonist Journal of Molecular Neuroscience. 18: 29-35. PMID 11931347 DOI: 10.1385/Jmn:18:1-2:29  0.33
2002 Blank M, Krause I, Fridkin M, Keller N, Kopolovic J, Goldberg I, Tobar A, Shoenfeld Y. Bacterial induction of autoantibodies to beta2-glycoprotein-I accounts for the infectious etiology of antiphospholipid syndrome. The Journal of Clinical Investigation. 109: 797-804. PMID 11901188 DOI: 10.1172/Jci12337  0.312
2002 Urieli-Shoval S, Shubinsky G, Linke RP, Fridkin M, Tabi I, Matzner Y. Adhesion of human platelets to serum amyloid A. Blood. 99: 1224-9. PMID 11830469 DOI: 10.1182/Blood.V99.4.1224  0.349
2002 Gozes I, Furman S, Vulih I, Segal-Ruder Y, Fridkin M, Brenneman D. VIP, novel proteins and peptide-mediated neuronal survival European Neuropsychopharmacology. 12: 145-146. DOI: 10.1016/S0924-977X(02)80092-X  0.352
2002 Hindi S, Grossman DP, Goldwaser I, Shechter Y, Fridkin M. Potentiating vanadium-evoked glucose metabolism by novel hydroxamate derivatives Letters in Peptide Science. 9: 235-254. DOI: 10.1007/Bf02447549  0.307
2001 Sharma A, Walters J, Gozes Y, Fridkin M, Brenneman D, Gozes I, Moody TW. A vasoactive intestinal peptide antagonist inhibits the growth of glioblastoma cells Journal of Molecular Neuroscience. 17: 331-339. PMID 11859929 DOI: 10.1385/Jmn:17:3:331  0.333
2001 Xu R, Abramson J, Fridkin M, Pecht I. SH2 domain-containing inositol polyphosphate 5′-phosphatase is the main mediator of the inhibitory action of the mast cell function-associated antigen Journal of Immunology. 167: 6394-6402. PMID 11714805 DOI: 10.4049/Jimmunol.167.11.6394  0.331
2001 Harel M, Kasher R, Nicolas A, Guss JM, Balass M, Fridkin M, Smit AB, Brejc K, Sixma TK, Katchalski-Katzir E, Sussman JL, Fuchs S. The binding site of acetylcholine receptor as visualized in the X-Ray structure of a complex between alpha-bungarotoxin and a mimotope peptide. Neuron. 32: 265-75. PMID 11683996 DOI: 10.1016/S0896-6273(01)00461-5  0.348
2001 Rahimipour S, Ben-Aroya N, Fridkin M, Koch Y. Design, synthesis, and evaluation of a long-acting, potent analogue of gonadotropin-releasing hormone. Journal of Medicinal Chemistry. 44: 3645-52. PMID 11606129 DOI: 10.1021/Jm010112G  0.314
2001 Gelber E, Granoth R, Fridkin M, Dreznik Z, Brenneman DE, Moody TW, Gozes I. A lipophilic vasoactive intestinal peptide analog enhances the antiproliferative effect of chemotherapeutic agents on cancer cell lines Cancer. 92: 2172-2180. PMID 11596035 DOI: 10.1002/1097-0142(20011015)92:8<2172::Aid-Cncr1560>3.0.Co;2-4  0.308
2001 Tsubery H, Ofek I, Cohen S, Fridkin M. N-terminal modifications of Polymyxin B nonapeptide and their effect on antibacterial activity Peptides. 22: 1675-1681. PMID 11587796 DOI: 10.1016/S0196-9781(01)00503-4  0.323
2001 Rahimipour S, Bilkis I, Péron V, Gescheidt G, Barbosa F, Mazur Y, Koch Y, Weiner L, Fridkin M. Generation of free radicals by emodic acid and its [D-Lys6]GnRH-conjugate. Photochemistry and Photobiology. 74: 226-36. PMID 11547560 DOI: 10.1562/0031-8655(2001)074<0226:Gofrbe>2.0.Co;2  0.312
2001 Ashur-Fabian O, Giladi E, Furman S, Steingart RA, Wollman Y, Fridkin M, Brenneman DE, Gozes I. Vasoactive intestinal peptide and related molecules induce nitrite accumulation in the extracellular milieu of rat cerebral cortical cultures. Neuroscience Letters. 307: 167-70. PMID 11438390 DOI: 10.1016/S0304-3940(01)01954-1  0.373
2001 Scherf T, Kasher R, Balass M, Fridkin M, Fuchs S, Katchalski-Katzir E. A beta -hairpin structure in a 13-mer peptide that binds alpha -bungarotoxin with high affinity and neutralizes its toxicity. Proceedings of the National Academy of Sciences of the United States of America. 98: 6629-34. PMID 11381118 DOI: 10.1073/Pnas.111164298  0.39
2001 Tisch-Idelson D, Fridkin M, Wientjes F, Aviram I. Structure-function relationship in the interaction of mastoparan analogs with neutrophil NADPH oxidase. Biochemical Pharmacology. 61: 1063-71. PMID 11301039 DOI: 10.1016/S0006-2952(01)00561-5  0.342
2001 Kasher R, Balass M, Scherf T, Fridkin M, Fuchs S, Katchalski-Katzir E. Design and synthesis of peptides that bind alpha-bungarotoxin with high affinity. Chemistry & Biology. 8: 147-55. PMID 11251289 DOI: 10.1016/S1074-5521(00)90063-2  0.405
2001 Shechter Y, Goldwaser I, Lavon I, Gershonov E, Mester B, Mironchik M, Patt LP, Fridkin M. A new approach for prolonging the half-life of peptides, proteins and low-molecular-weight drugs in vivo Drugs of the Future. 26: 669-676. DOI: 10.1358/Dof.2001.026.07.858711  0.345
2000 Sigalov E, Fridkin M, Brenneman DE, Gozes I. VIP-related protection against iodoacetate toxicity in pheochromocytoma (PC12) cells: A model for ischemic/hypoxic injury Journal of Molecular Neuroscience. 15: 147-154. PMID 11303779 DOI: 10.1385/Jmn:15:3:147  0.325
2000 Steingart RA, Solomon B, Brenneman DE, Fridkin M, Gozes I. VIP and peptides related to activity-dependent neurotrophic factor protect PC12 cells against oxidative stress Journal of Molecular Neuroscience. 15: 137-145. PMID 11303778 DOI: 10.1385/Jmn:15:3:137  0.387
2000 Tirosh B, Fridkin M, Tzehoval E, Vadai E, Lemonnier FA, Eisenbach L. Antigenicity and immunogenicity of an intracellular delivery system of major histocompatibility complex class I epitopes that bypasses proteasome processing Journal of Immunotherapy. 23: 622-630. PMID 11186150 DOI: 10.1097/00002371-200011000-00003  0.37
2000 Eilat E, Fridkin M, Mozes E. A peptide based on the CDR1 of a pathogenic anti-DNA antibody is more efficient than its analogs in inhibiting autoreactive T cells Immunobiology. 202: 383-393. PMID 11131154 DOI: 10.1016/S0171-2985(00)80041-8  0.372
2000 Brosh N, Zinger H, Fridkin M, Mozes E. A peptide based on the sequence of the CDR3 of a murine anti-DNA mAb is a better modulator of experimental SLE than its single amino acid-substituted analogs Cellular Immunology. 205: 52-61. PMID 11078607 DOI: 10.1006/Cimm.2000.1711  0.393
2000 Tsubery H, Ofek I, Cohen S, Fridkin M. Structure - Function studies of Polymyxin B nonapeptide: Implications to sensitization of Gram-negative bacteria Journal of Medicinal Chemistry. 43: 3085-3092. PMID 10956216 DOI: 10.1021/Jm0000057  0.354
2000 Yahalom D, Rahimipour S, Koch Y, Ben-Aroya N, Fridkin M. Design and synthesis of potent hexapeptide and heptapeptide gonadotropin-releasing hormone antagonists by truncation of a decapeptide analogue sequence. Journal of Medicinal Chemistry. 43: 2831-6. PMID 10956191 DOI: 10.1021/Jm990433G  0.361
2000 Yahalom D, Rahimipour S, Koch Y, Ben-Aroya N, Fridkin M. Structure-activity studies of reduced-size gonadotropin-releasing hormone agonists derived from the sequence of an endothelin antagonist. Journal of Medicinal Chemistry. 43: 2824-30. PMID 10956190 DOI: 10.1021/Jm990432O  0.405
2000 Dayan M, Segal R, Sthoeger Z, Waisman A, Brosh N, Elkayam O, Eilat E, Fridkin M, Mozes E. Immune response of SLE patients to peptides based on the complementarity determining regions of a pathogenic anti-DNA monoclonal antibody. Journal of Clinical Immunology. 20: 187-94. PMID 10941826 DOI: 10.1023/A:1006685413157  0.362
2000 Granoth R, Fridkin M, Gozes I. VIP and the potent analog, stearyl-Nle17-VIP, induce proliferation of keratinocytes Febs Letters. 475: 78-83. PMID 10858492 DOI: 10.1016/S0014-5793(00)01628-8  0.317
2000 Granoth R, Fridkin M, Rubinraut S, Gozes I. VIP-derived sequences modified by N-terminal stearyl moiety induce cell death: The human keratinocyte as a model Febs Letters. 475: 71-77. PMID 10858491 DOI: 10.1016/S0014-5793(00)01629-X  0.412
2000 Brosh N, Dayan M, Fridkin M, Mozes E. A peptide based on the CDR3 of an anti-DNA antibody of experimental SLE origin is also a dominant T-cell epitope in (NZBXNZW)F1 lupus-prone mice Immunology Letters. 72: 61-68. PMID 10789683 DOI: 10.1016/S0165-2478(00)00161-9  0.359
2000 Yavin EJ, Preciado-Patt L, Rosen O, Yaron M, Suessmuth RD, Levartowsky D, Jung G, Lider O, Fridkin M. Serum amyloid A-derived peptides, present in human rheumatic synovial fluids, induce the secretion of interferon-γ by human CD4+ T-lymphocytes Febs Letters. 472: 259-262. PMID 10788622 DOI: 10.1016/S0014-5793(00)01470-8  0.381
2000 Offen D, Sherki Y, Melamed E, Fridkin M, Brenneman DE, Gozes I. Vasoactive intestinal peptide (VIP) prevents neurotoxicity in neuronal cultures: relevance to neuroprotection in Parkinson's disease. Brain Research. 854: 257-62. PMID 10784133 DOI: 10.1016/S0006-8993(99)02375-6  0.347
2000 Yahalom D, Koch Y, Ben-Aroya N, Fridkin M. Hexapeptide and cyclic pentapeptide endothelin antagonists directly activate pituitary gonadotropin-releasing hormone receptors. Molecular Pharmacology. 57: 718-24. PMID 10727517 DOI: 10.1124/Mol.57.4.718  0.373
2000 Carmon L, El-Shami KM, Paz A, Pascolo S, Tzehoval E, Tirosh B, Koren R, Feldman M, Fridkin M, Lemonnier FA, Eisenbach L. Novel breast-tumor-associated MUC1-derived peptides: Characterization in D(b-)/- x β2 microglobulin (β2m) null mice transgenic for a chimeric HLA- A2.1/D(b)-β2 microglobulin single chain International Journal of Cancer. 85: 391-397. PMID 10652432 DOI: 10.1002/(Sici)1097-0215(20000201)85:3<391::Aid-Ijc16>3.0.Co;2-V  0.363
2000 Philosof-Oppenheimer R, Hampe CS, Schlessinger K, Fridkin M, Pecht I. An immunoreceptor tyrosine-based inhibitory motif, with serine at site Y-2, binds SH2-domain-containing phosphatases. European Journal of Biochemistry. 267: 703-11. PMID 10651806 DOI: 10.1046/J.1432-1327.2000.01044.X  0.389
2000 Tsubery H, Ofek I, Cohen S, Fridkin M. The functional association of polymyxin B with bacterial lipopolysaccharide is stereospecific: Studies on polymyxin B nonapeptide Biochemistry. 39. DOI: 10.1021/Bi000386Q  0.304
1999 Zia H, Leyton J, Casibang M, Hau V, Brenneman D, Fridkin M, Gozes I, Moody TW. (N-Stearyl, Norleucine17) VIP hybrid inhibits the growth of pancreatic cancer cell lines Life Sciences. 66: 379-387. PMID 10670826 DOI: 10.1016/S0024-3205(99)00604-9  0.301
1999 Tirosh B, el-Shami K, Vaisman N, Carmon L, Bar-Haim E, Vadai E, Feldman M, Fridkin M, Eisenbach L. Immunogenicity of H-2Kb-low affinity, high affinity, and covalently-bound peptides in anti-tumor vaccination. Immunology Letters. 70: 21-8. PMID 10541048 DOI: 10.1016/S0165-2478(99)00115-7  0.416
1999 Hill JM, Lee SJ, Dibbern DA, Fridkin M, Gozes I, Brenneman DE. Pharmacologically distinct vasoactive intestinal peptide binding sites: CNS localization and role in embryonic growth. Neuroscience. 93: 783-91. PMID 10465461 DOI: 10.1016/S0306-4522(99)00155-4  0.41
1999 Yahalom D, Koch Y, Ben-Aroya N, Fridkin M. Synthesis and bioactivity of fatty acid-conjugated GnRH derivatives. Life Sciences. 64: 1543-52. PMID 10353619 DOI: 10.1016/S0024-3205(99)00091-0  0.402
1999 Blank M, Shoenfeld Y, Cabilly S, Heldman Y, Fridkin M, Katchalski-Katzir E. Prevention of experimental antiphospholipid syndrome and endothelial cell activation by synthetic peptides. Proceedings of the National Academy of Sciences of the United States of America. 96: 5164-8. PMID 10220436 DOI: 10.1073/Pnas.96.9.5164  0.422
1999 Gozes I, Perl O, Giladi E, Davidson A, Ashur-Fabian O, Rubinraut S, Fridkin M. Mapping the active site in vasoactive intestinal peptide to a core of four amino acids: Neuroprotective drug design Proceedings of the National Academy of Sciences of the United States of America. 96: 4143-4148. PMID 10097177 DOI: 10.1073/Pnas.96.7.4143  0.45
1999 Könen-Waisman S, Cohen A, Fridkin M, Cohen IR. Self heat-shock protein (hsp60) peptide serves in a conjugate vaccine against a lethal pneumococcal infection. The Journal of Infectious Diseases. 179: 403-13. PMID 9878025 DOI: 10.1086/314590  0.318
1999 Preciado-Patt L, Hershkovitz R, Lider O, Feiertag S, Jung G, Fridkin M. A study of extracellular matrix-cell adhesion peptidic epitopes related to human serum amyloid A (SAA) Letters in Peptide Science. 6: 99-108. DOI: 10.1007/Bf02443623  0.383
1998 Gozes I, Perl O, Zamostiano R, Rubinraut S, Fridkin M, Shochat L, Lewin LM. Multiple actions of a hybrid PACAP antagonist: neuronal cell killing and inhibition of sperm motility. Annals of the New York Academy of Sciences. 865: 266-73. PMID 9928021 DOI: 10.1111/J.1749-6632.1998.Tb11187.X  0.366
1998 Gatt ME, Urieli-Shoval S, Preciado-Patt L, Fridkin M, Calco S, Azar Y, Matzner Y. Effect of serum amyloid A on selected in vitro functions of isolated human neutrophils. The Journal of Laboratory and Clinical Medicine. 132: 414-20. PMID 9823935 DOI: 10.1016/S0022-2143(98)90112-3  0.321
1998 Katz-Levy Y, Dayan M, Wirguin I, Fridkin M, Sela M, Mozes E. Single amino acid analogs of a myasthenogenic peptide modulate specific T cell responses and prevent the induction of experimental autoimmune myasthenia gravis Journal of Neuroimmunology. 85: 78-86. PMID 9627000 DOI: 10.1016/S0165-5728(97)00265-8  0.33
1998 Zupan V, Hill JM, Brenneman DE, Gozes I, Fridkin M, Robberecht P, Evrard P, Gressens P. Involvement of pituitary adenylate cyclase-activating polypeptide II vasoactive intestinal peptide 2 receptor in mouse neocortical astrocytogenesis. Journal of Neurochemistry. 70: 2165-73. PMID 9572304 DOI: 10.1046/J.1471-4159.1998.70052165.X  0.347
1998 Gozes I, Bachar M, Bardea A, Davidson A, Rubinraut S, Fridkin M. Protection against developmental deficiencies by a lipophilic VIP analogue. Neurochemical Research. 23: 689-93. PMID 9566607 DOI: 10.1023/A:1022494907001  0.307
1998 Yavin EJ, Fridkin M. Peptides derived from human C-reactive protein inhibit the enzymatic activities of human leukocyte elastase and cathepsin G: Use of overlapping peptide sequences to identify a unique inhibitor Journal of Peptide Research. 51: 282-289. PMID 9560003 DOI: 10.1111/J.1399-3011.1998.Tb00425.X  0.404
1998 Rajnavölgyi E, Horváth A, Gogolák P, Tóth GK, Fazekas G, Fridkin M, Pecht I. Characterizing immunodominant and protective influenza hemagglutinin epitopes by functional activity and relative binding to major histocompatibility complex class II sites. European Journal of Immunology. 27: 3105-14. PMID 9464794 DOI: 10.1002/Eji.1830271205  0.377
1998 Rahimipour S, Weiner L, Shrestha-Dawadi PB, Bittner S, Koch Y, Fridkin M. Cytotoxic peptides: Naphthoquinonyl derivatives of luteinizing hormone-releasing hormone International Journal of Peptide Research and Therapeutics. 5: 421-427. DOI: 10.1007/Bf02443499  0.373
1998 Eisenbach L, Mandelboim O, Bar-Haim E, Carmon L, Copcow H, El-Shami K, Paz A, Popovic D, Vadai E, Tzehoval E, Feldman M, Fridkin M. Tumor-associated antigen peptides as anti-metastatic vaccines Letters in Peptide Science. 5: 323-328. DOI: 10.1007/Bf02443479  0.337
1997 Gozes I, Bachar M, Bardea A, Davidson A, Rubinraut S, Fridkin M, Giladi E. Protection against developmental retardation in apolipoprotein E-deficient mice by a fatty neuropeptide: implications for early treatment of Alzheimer's disease. Journal of Neurobiology. 33: 329-42. PMID 9298769 DOI: 10.1002/(Sici)1097-4695(199709)33:3<329::Aid-Neu10>3.0.Co;2-A  0.388
1997 Granoth R, Vadai E, Burstein Y, Fridkin M, Tzehoval E. Tuftsin-THF-gamma 2 chimeric peptides: potential novel immunomodulators. Immunopharmacology. 37: 43-52. PMID 9285243 DOI: 10.1016/S0162-3109(97)00002-7  0.399
1997 Hershkoviz R, Preciado-Patt L, Lider O, Fridkin M, Dastych J, Metcalfe DD, Mekori YA. Extracellular matrix-anchored serum amyloid A preferentially induces mast cell adhesion. The American Journal of Physiology. 273: C179-87. PMID 9252455 DOI: 10.1152/Ajpcell.1997.273.1.C179  0.341
1997 Gressens P, Marret S, Hill JM, Brenneman DE, Gozes I, Fridkin M, Evrard P. Vasoactive intestinal peptide prevents excitotoxic cell death in the murine developing brain. The Journal of Clinical Investigation. 100: 390-7. PMID 9218516 DOI: 10.1172/Jci119545  0.361
1997 Katz-Levy Y, Paas-Rozner M, Kirshner S, Dayan M, Zisman E, Fridkin M, Wirguin I, Sela M, Mozes E. A peptide composed of tandem analogs of two myasthenogenic T cell epitopes interferes with specific autoimmune responses Proceedings of the National Academy of Sciences of the United States of America. 94: 3200-3205. PMID 9096370 DOI: 10.1073/Pnas.94.7.3200  0.359
1997 Gershonov E, Granoth R, Tzehoval E, Gaoni Y, Fridkin M. 1-Aminocyclobutanecarboxylic acid derivatives as novel structural elements in bioactive peptides: application to tuftsin analogs. Journal of Medicinal Chemistry. 39: 4833-43. PMID 8941397 DOI: 10.1021/Jm960390T  0.441
1997 Giladi E, Davidson A, Bachar M, Bardea A, Rubinraut S, Fridkin M, Brenneman D, Gozes I. Protection against developmental and learning impairments in apolipoprotein e-deficient mice by activity-dependent femtomolar-acting peptides Neuroscience Letters. 237: S19. DOI: 10.1016/S0304-3940(97)90077-X  0.333
1997 Yavin EJ, Yan L, Desiderio DM, Pontet M, Fridkin M. Inhibition of human leukocyte elastase and cathepsin G by extended peptides and subunits derived from human C-reactive protein Letters in Peptide Science. 4: 157-166. DOI: 10.1007/Bf02443528  0.393
1996 Preciado-Patt L, Pras M, Fridkin M. Binding of human serum amyloid A (hSAA) and its high-density lipoprotein3 complex (hSAA-HDL3) to human neutrophils. Possible implication to the function of a protein of an unknown physiological role. International Journal of Peptide and Protein Research. 48: 503-13. PMID 8985783 DOI: 10.1111/J.1399-3011.1996.Tb00869.X  0.342
1996 Yavin EJ, Yan L, Desiderio DM, Fridkin M. Synthetic peptides derived from the sequence of human C-reactive protein inhibit the enzymatic activities of human leukocyte elastase and human leukocyte cathepsin G. International Journal of Peptide and Protein Research. 48: 465-76. PMID 8956080 DOI: 10.1111/J.1399-3011.1996.Tb00865.X  0.43
1996 Kirshner SL, Zisman E, Fridkin M, Sela M, Mozes E. Altered peptide ligands of a myasthenogenic epitope as modulators of specific T-cell responses Scandinavian Journal of Immunology. 44: 512-521. PMID 8947604 DOI: 10.1046/J.1365-3083.1996.D01-330.X  0.39
1996 Zisman E, Katz-Levy Y, Dayan M, Kirshner SL, Paas-Rozner M, Karni A, Abramskyi O, Brautbar C, Fridkin M, Sela M, Mozes E. Peptide analogs to pathogenic epitopes of the human acetylcholine receptor a subunit as potential modulators of myasthenia gravis Proceedings of the National Academy of Sciences of the United States of America. 93: 4492-4497. PMID 8633096 DOI: 10.1073/Pnas.93.9.4492  0.405
1996 Gozes I, Bardea A, Reshef A, Zamostiano R, Zhukovsky S, Rubinraut S, Fridkin M, Brenneman DE. Neuroprotective strategy for Alzheimer disease: Intranasal administration of a fatty neuropeptide Proceedings of the National Academy of Sciences of the United States of America. 93: 427-432. PMID 8552653 DOI: 10.1073/Pnas.93.1.427  0.357
1996 Rahimipour S, Weiner L, Fridkin M, Shrestha-Dawadi PB, Bittner S. Novel naphthoquinonyl derivatives: Potential structural components for the synthesis of cytotoxic peptides Letters in Peptide Science. 3: 263-274. DOI: 10.1007/Bf00127660  0.398
1995 Gozes I, Fridkin M, Brenneman DE. A VIP hybrid antagonist: From developmental neurobiology to clinical applications Cellular and Molecular Neurobiology. 15: 675-687. PMID 8719036 DOI: 10.1007/Bf02071131  0.373
1995 Philosof-Oppenheimer R, Pecht I, Fridkin M. The 2,4-dinitrophenyl group for protection of hydroxyl function of tyrosine during solid-phase peptide synthesis International Journal of Peptide and Protein Research. 45: 116-121. PMID 7782158 DOI: 10.1111/J.1399-3011.1995.Tb01029.X  0.371
1995 Leibovitz D, Koch Y, Fridkin M, Pitzer F, Zwickl P, Dantes A, Baumeister W, Amsterdam A. Archaebacterial and eukaryotic proteasomes prefer different sites in cleaving gonadotropin-releasing hormone. The Journal of Biological Chemistry. 270: 11029-32. PMID 7744730 DOI: 10.1074/Jbc.270.19.11029  0.31
1995 Mandelboim O, Vadai E, Fridkin M, Katz-Hillel A, Feldman M, Berke G, Eisenbach L. Regression of established murine carcinoma metastases following vaccination with tumour-associated antigen peptides Nature Medicine. 1: 1179-1183. PMID 7584991 DOI: 10.1038/Nm1195-1179  0.362
1995 Lilling G, Wollman Y, Goldstein MN, Rubinraut S, Fridkin M, Brenneman DE, Gozes I. Inhibition of human neuroblastoma growth by a specific VIP antagonist. Journal of Molecular Neuroscience : Mn. 5: 231-9. PMID 7577366 DOI: 10.1007/Bf02736724  0.327
1995 Eisenbach L, Mandelboim O, Porgador A, Plaksin D, Fridkin M. 36 Gene and peptide therapy of tumor metastases in murine models European Journal of Cancer. 31: S8. DOI: 10.1016/0959-8049(95)95288-H  0.368
1995 Yavin EJ, Rosen O, Pontet M, Shephard EG, Fridkin M. Proteolysis of human C-reactive protein by neutrophil-derived lysosomal enzymes generates peptides which modulate neutrophil function: Implication to the anti-inflammatory mechanism Letters in Peptide Science. 2: 7-16. DOI: 10.1007/Bf00122918  0.43
1994 Wollman Y, Lilling G, Goldstein MN, Fridkin M, Gozes I. Vasoactive intestinal peptide: a growth promoter in neuroblastoma cells. Brain Research. 624: 339-41. PMID 8252411 DOI: 10.1016/0006-8993(93)90100-2  0.336
1994 Mandelboim O, Berke G, Fridkin M, Feldman M, Eisenstein M, Eisenbach L. CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma Nature. 369: 67-71. PMID 8164742 DOI: 10.1038/369067A0  0.395
1994 Gozes I, Reshef A, Salah D, Rubinraut S, Fridkin M. Stearyl-norleucine-vasoactive intestinal peptide (VIP): A novel VIP analog for noninvasive impotence treatment Endocrinology. 134: 2121-2125. PMID 8156912 DOI: 10.1210/Endo.134.5.8156912  0.336
1994 Landsmann P, Rosen O, Pontet M, Pras M, Levartowsky D, Shephard EG, Fridkin M. Binding of human serum amyloid P component (hSAP) to human neutrophils European Journal of Biochemistry. 223: 805-811. PMID 8055957 DOI: 10.1111/J.1432-1033.1994.Tb19056.X  0.355
1994 Preciado-Patt L, Levartowsky D, Prass M, Hershkoviz R, Lider O, Fridkin M. Inhibition of cell adhesion to glycoproteins of the extracellular matrix by peptides corresponding to serum amyloid A. Toward understanding the physiological role of an enigmatic protein. European Journal of Biochemistry / Febs. 223: 35-42. PMID 8033906 DOI: 10.1111/J.1432-1033.1994.Tb18963.X  0.429
1994 Leibovitz D, Koch Y, Pitzer F, Fridkin M, Dantes A, Baumeister W, Amsterdam A. Sequential degradation of the neuropeptide gonadotropin-releasing hormone by the 20 S granulosa cell proteasomes. Febs Letters. 346: 203-6. PMID 8013634 DOI: 10.1016/0014-5793(94)00472-2  0.305
1994 Gressens P, Hill JM, Paindaveine B, Gozes I, Fridkin M, Brenneman DE. Severe microcephaly induced by blockade of vasoactive intestinal peptide function in the primitive neuroepithelium of the mouse. The Journal of Clinical Investigation. 94: 2020-7. PMID 7962548 DOI: 10.1172/Jci117555  0.341
1994 Aboudy Y, Mendelson E, Shalit I, Bessalle R, Fridkin M. Activity of two synthetic amphiphilic peptides and magainin-2 against herpes simplex virus types 1 and 2 International Journal of Peptide and Protein Research. 43: 573-582. PMID 7928088 DOI: 10.1111/J.1399-3011.1994.Tb00559.X  0.367
1994 SONE M, SMITH DM, GHATEI MA, GOZES I, BRENNEMAN DE, FRIDKIN M, BLOOM SR. PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP)/VASOACTIVE INTESTINAL PEPTIDE (VIP) RECEPTOR SUBTYPES IN RAT TISSUES: INVESTIGATION OF RECEPTOR BINDING, A NOVEL VIP RECEPTOR ANTAGONIST AND CHEMICAL CROSS-LINKING Biomedical Research. 15: 145-153. DOI: 10.2220/Biomedres.15.145  0.304
1993 Bessalle R, Gorea A, Shalit I, Metzger JW, Dass C, Desiderio DM, Fridkin M. Structure-function studies of amphiphilic antibacterial peptides. Journal of Medicinal Chemistry. 36: 1203-9. PMID 8487258 DOI: 10.1021/Jm00061A011  0.424
1993 Biondi L, Filira F, Rocchi R, Tzehoval E, Fridkin M. Synthesis and biological activity of [L-hydroxyproline]3-tuftsin analogue and its alpha- or beta-O-D-glucosylated derivatives. International Journal of Peptide and Protein Research. 41: 43-51. PMID 8436445 DOI: 10.1111/J.1399-3011.1993.Tb00114.X  0.307
1993 Gressens P, Hill JM, Gozes I, Fridkin M, Brenneman DE. Growth factor function of vasoactive intestinal peptide in whole cultured mouse embryos Nature. 362: 155-158. PMID 8383805 DOI: 10.1038/362155A0  0.318
1993 Gechtman Z, Sharma R, Kreizman T, Fridkin M, Shaltiel S. Synthetic peptides derived from the sequence around the plasmin cleavage site in vitronectin. Use in mapping the PAI-1 binding site. Febs Letters. 315: 293-7. PMID 7678553 DOI: 10.1016/0014-5793(93)81181-X  0.324
1992 Bessalle R, Haas H, Goria A, Shalit I, Fridkin M. Augmentation of the antibacterial activity of magainin by positive-charge chain extension. Antimicrobial Agents and Chemotherapy. 36: 313-7. PMID 1605597 DOI: 10.1128/Aac.36.2.313  0.328
1992 Gozes I, Fridkin M. A fatty neuropeptide. Potential drug for noninvasive impotence treatment in a rat model Journal of Clinical Investigation. 90: 810-814. PMID 1522236 DOI: 10.1097/00006254-199303000-00022  0.367
1992 Ying SC, Shephard E, de Beer FC, Siegel JN, Harris D, Gewurz BE, Fridkin M, Gewurz H. Localization of sequence-determined neoepitopes and neutrophil digestion fragments of C-reactive protein utilizing monoclonal antibodies and synthetic peptides. Molecular Immunology. 29: 677-87. PMID 1374844 DOI: 10.1016/0161-5890(92)90205-C  0.371
1991 Rocchi R, Biondi L, Filira F, Tzehoval E, Dagan S, Fridkin M. Glyco-tuftsin derivatives modulate interleukin-1 and tumor necrosis factor production. International Journal of Peptide and Protein Research. 37: 161-6. PMID 1869367 DOI: 10.1111/J.1399-3011.1991.Tb00265.X  0.358
1990 Rosen O, Rubinraut S, Fridkin M. Thiolysis of the 3-nitro-2-pyridinesulfenyl (Npys) protecting group: An approach towards a general deprotection scheme in peptide synthesis International Journal of Peptide and Protein Research. 35: 545-549. PMID 2401596 DOI: 10.1111/J.1399-3011.1990.Tb00260.X  0.311
1990 Surkis R, Rubinraut S, Dagan S, Tzehoval E, Fridkin M, Ben Yoseph R, Catane R. Polytuftsin: a potential precursor for slow release of the phagocytosis stimulating peptide tuftsin. The International Journal of Biochemistry. 22: 193-5. PMID 2332102 DOI: 10.1016/0020-711X(90)90183-4  0.372
1990 Bessalle R, Kapitkovsky A, Gorea A, Shalit I, Fridkin M. All-D-magainin: chirality, antimicrobial activity and proteolytic resistance. Febs Letters. 274: 151-5. PMID 2253768 DOI: 10.1016/0014-5793(90)81351-N  0.351
1989 Fridkin M, Najjar VA. Tuftsin: its chemistry, biology, and clinical potential Critical Reviews in Biochemistry and Molecular Biology. 24: 1-40. PMID 2667894 DOI: 10.3109/10409238909082550  0.397
1989 Gozes I, Meltzer E, Rubinrout S, Brenneman DE, Fridkin M. Vasoactive intestinal peptide potentiates sexual behavior: Inhibition by novel antagonist Endocrinology. 125: 2945-2949. PMID 2583049 DOI: 10.1210/Endo-125-6-2945  0.381
1988 Fuchs S, Neumann D, Safran A, Souroujon M, Barchan D, Fridkin M, Gershoni JM, Mantegazza R, Pizzighella S. Synthetic peptides and their antibodies in the analysis of the acetylcholine receptor. Annals of the New York Academy of Sciences. 505: 256-71. PMID 2446550 DOI: 10.1111/J.1749-6632.1987.Tb51295.X  0.365
1987 Rocchi R, Biondi L, Cavaggion F, Filira F, Gobbo M, Dagan S, Fridkin M. Synthesis and biological activity of tuftsin and rigin derivatives containing monosaccharides or monosaccharide derivatives. International Journal of Peptide and Protein Research. 29: 262-75. PMID 3570666 DOI: 10.1111/J.1399-3011.1987.Tb02253.X  0.361
1986 Dagan S, Gottlieb P, Tzehoval E, Feldman M, Fridkin M, Yasumura K, Okamoto K, Yajima H. Tuftsin analogues: synthesis, structure-function relationships, and implications for specificity of tuftsin's bioactivity. Journal of Medicinal Chemistry. 29: 1961-8. PMID 3761314 DOI: 10.1021/Jm00160A027  0.387
1986 Neumann D, Barchan D, Fridkin M, Fuchs S. Analysis of ligand binding to the synthetic dodecapeptide 185-196 of the acetylcholine receptor α subunit Proceedings of the National Academy of Sciences of the United States of America. 83: 9250-9253. PMID 3466185 DOI: 10.1073/Pnas.83.23.9250  0.385
1986 Buchta R, Fridkin M, Pontet M, Romeo D. Synthetic peptides from C-reactive protein containing tuftsin-related sequences Peptides. 7: 961-968. PMID 3031632 DOI: 10.1016/0196-9781(86)90121-X  0.437
1986 Kris RM, Lax I, Sasson I, Copf B, Werlin S, Gullick W, Waterfield MD, Ullrich A, Fridkin M, Schlessinger J. Synthetic peptide approach to the analysis of kinase activities of avian EGF receptor and v-erbB protein. Biochimie. 67: 1095-101. PMID 3000459 DOI: 10.1016/S0300-9084(85)80106-1  0.305
1986 Buchta R, Bondi E, Fridkin M. Peptides related to the calcium binding domains II and III of calmodulin. Synthesis and calmodulin-like features International Journal of Peptide and Protein Research. 28: 289-297. PMID 2946646 DOI: 10.1111/J.1399-3011.1986.Tb03258.X  0.369
1986 Souroujon M, Neumann D, Pizzighella S, Fridkin M, Fuchs S. Mapping of the cAMP-dependent phosphorylation sites on the acetylcholine receptor. The Embo Journal. 5: 543-546. DOI: 10.1002/J.1460-2075.1986.Tb04244.X  0.322
1985 Werner H, Koch Y, Fridkin M, Fahrenkrug J, Gozes I. High levels of vasoactive intestinal peptide in human milk. Biochemical and Biophysical Research Communications. 133: 228-32. PMID 4074363 DOI: 10.1016/0006-291X(85)91865-0  0.386
1985 Buchta R, Fridkin M. Introduction of the dansyl group into histidine and tyrosine residues in peptides and proteins Biochemical and Biophysical Research Communications. 130: 350-357. PMID 4026836 DOI: 10.1016/0006-291X(85)90424-3  0.397
1985 Bodner M, Fridkin M, Gozes I. Coding sequences for vasoactive intestinal peptide and PHM-27 peptide are located on two adjacent exons in the human genome Proceedings of the National Academy of Sciences of the United States of America. 82: 3548-3551. PMID 2987932 DOI: 10.1073/Pnas.82.11.3548  0.342
1985 Werner H, Fridkin M, Aviv D, Koch Y. Immunoreactive and bioactive somatostatin-like material is present in tobacco (Nicotiana tabacum). Peptides. 6: 797-802. PMID 2867523 DOI: 10.1016/0196-9781(85)90304-3  0.307
1985 Werner H, Amarant T, Millar RP, Fridkin M, Koch Y. Immunoreactive and biologically active somatostatin in human and sheep milk. European Journal of Biochemistry / Febs. 148: 353-7. PMID 2859195 DOI: 10.1111/J.1432-1033.1985.Tb08846.X  0.379
1985 Neumann D, Gershoni JM, Fridkin M, Fuchs S. Antibodies to synthetic peptides as probes for the binding site on the α subunit of the acetylcholine receptor Proceedings of the National Academy of Sciences of the United States of America. 82: 3490-3493. PMID 2582416 DOI: 10.1073/Pnas.82.10.3490  0.354
1985 Gozes I, Bodner M, Shani Y, Avidor R, Brill E, Fridkin M. Structure and expression of the vasoactive intestinal peptide (VIP) gene Regulatory Peptides. 10: S14. DOI: 10.1016/0167-0115(85)90304-0  0.343
1984 Gozes I, Bodner M, Shani Y, Fridkin M. Detection of mRNAs containing regulatory peptide coding sequences using synthetic oligodeoxynucleotides Journal of Cellular Biochemistry. 26: 147-156. PMID 6526855 DOI: 10.1002/Jcb.240260303  0.373
1984 Gottlieb P, Hazum E, Tzehoval E, Feldman M, Segal S, Fridkin M. Receptor-mediated endocytosis of tuftsin by macrophage cells. Biochemical and Biophysical Research Communications. 119: 203-11. PMID 6322775 DOI: 10.1016/0006-291X(84)91639-5  0.323
1984 Neumann D, Fridkin M, Fuchs S. Anti-acetylcholine receptor response achieved by immunization with a synthetic peptide from the receptor sequence Biochemical and Biophysical Research Communications. 121: 673-679. PMID 6203534 DOI: 10.1016/0006-291X(84)90234-1  0.369
1983 Knyszynski A, Gottlieb P, Fridkin M. Inhibition by tuftsin of Rauscher virus leukemia development in mice Journal of the National Cancer Institute. 71: 87-90. PMID 6575215 DOI: 10.1093/Jnci/71.1.87  0.318
1983 Gottlieb P, Tzehoval E, Feldman M, Segal S, Fridkin M. Peptide fragments from the tuftsin containing domain of immunoglobulin G synthesis and biological activity Biochemical and Biophysical Research Communications. 115: 193-200. PMID 6311202 DOI: 10.1016/0006-291X(83)90988-9  0.409
1983 de L Milton RC, King JA, Badminton MN, Tobler CJ, Lindsey GG, Fridkin M, Millar RP. Comparative structure-activity studies on mammalian [Arg8] LH-RH and chicken [Gln8] LH-RH by fluorimetric titration. Biochemical and Biophysical Research Communications. 111: 1082-8. PMID 6301482 DOI: 10.1016/0006-291X(83)91410-9  0.35
1982 Amarant T, Fridkin M, Koch Y. Luteinizing hormone-releasing hormone and thyrotropin-releasing hormone in human and bovine milk. European Journal of Biochemistry / Febs. 127: 647-50. PMID 6816590 DOI: 10.1111/J.1432-1033.1982.Tb06921.X  0.307
1982 Gottlieb P, Beretz A, Fridkin M. Tuftsin analogs for probing its specific receptor site on phagocytic cells European Journal of Biochemistry. 125: 631-638. PMID 6288377 DOI: 10.1111/J.1432-1033.1982.Tb06729.X  0.327
1981 Stern M, Warshawksy A, Fridkin M. Polymeric 2-mercaptopyridine and 2-mercapto-nitrobenzene derivatives. New reagents for peptide synthesis International Journal of Peptide and Protein Research. 17: 531-538. PMID 7309358 DOI: 10.1002/Chin.198135352  0.331
1981 Fridkin M, Gottlieb P. Tuftsin, Thr-Lys-Pro-Arg - Anatomy of an immunologically active peptide Molecular and Cellular Biochemistry. 41: 73-97. PMID 7035869 DOI: 10.1007/Bf00225299  0.429
1981 Hazum E, Fridkin M, Baram T, Koch Y. Synthesis, biological activity and resistance to enzymic degradation of luteinizing hormone--releasing hormone analogues modified at position 7. Febs Letters. 123: 300-2. PMID 7014245 DOI: 10.1016/0014-5793(81)80313-4  0.361
1980 Stabinsky Y, Gottlieb P, Fridkin M. The phagocytosis stimulating peptide tuftsin: Further look into structure-function relationships Molecular and Cellular Biochemistry. 30: 165-170. PMID 6893216 DOI: 10.1007/Bf00230170  0.4
1980 Stabinsky Y, Bar-Shavit Z, Fridkin M, Goldman R. On the mechanism of action of the phagocytosis-stimulating peptide tuftsin Molecular and Cellular Biochemistry. 30: 71-77. PMID 6247642 DOI: 10.1007/Bf00227920  0.334
1980 Bar-Shavit Z, Goldman R, Stabinsky Y, Gottlieb P, Fridkin M, Teichberg VI, Blumberg S. Enhancement of phagocytosis - a newly found activity of substance P residing in its N-terminal tetrapeptide sequence. Biochemical and Biophysical Research Communications. 94: 1445-51. PMID 6156684 DOI: 10.1016/0006-291X(80)90581-1  0.304
1979 Spirer Z, Zakuth V, Diamant S, Stabinsky Y, Fridkin M. Studies on the activity of phorbol myrystate acetate on the human polymorphonuclear leukocytes Experientia. 35: 830-831. PMID 467608 DOI: 10.1007/Bf01968279  0.353
1979 Stern M, Warshawsky A, Fridkin M. Facile thiolytic removal of the o-nitrophenylsulphenyl amino-protecting group International Journal of Peptide and Protein Research. 13: 315-319. PMID 429104 DOI: 10.1002/Chin.197927336  0.376
1979 Tzehoval E, Segal S, Stabinsky Y, Fridkin M, Spirer Z, Feldman M. Immunostimulation by an Ig derived tetrapeptide, tuftsin Springer Seminars in Immunopathology. 2: 205-214. DOI: 10.1007/978-3-642-67809-7_10  0.332
1979 Stabinsky Y, Fridkin M, Zakuth V, Spirer Z. Synthesis And Biological Activity Of Tuftsin And Of (O=C Thr1)-Tuftsin. A Novel Synthetic Route To Peptides Containing N-Terminal L-O=C Thr And L-O=C Ser Residues Cheminform. 10. DOI: 10.1002/Chin.197907325  0.301
1978 Goren HJ, Fridkin M. Thiolysis of Nim-2,4-dinitrophenyl-histidine peptides with 2-mercaptoethanol. An explannation for the pH optimum International Journal of Peptide and Protein Research. 11: 1-8. PMID 631983 DOI: 10.1111/J.1399-3011.1978.Tb02814.X  0.313
1978 Stabinsky Y, Gottlieb P, Zakuth V, Spirer Z, Fridkin M. Specific binding sites for the phagocytosis stimulating peptide tuftsin on human polymorphonuclear leukocytes and monocytes. Biochemical and Biophysical Research Communications. 83: 599-606. PMID 581265 DOI: 10.1016/0006-291X(78)91032-X  0.32
1978 Hazum E, Fridkin M, Meidan R, Koch Y. Mercuration of tryptophan in luteinizing hormone-releasing hormone International Journal of Biochemistry. 9: 385-388. PMID 352765 DOI: 10.1016/0020-711X(78)90050-2  0.322
1978 Tzehoval E, Segal S, Stabinsky Y, Fridkin M, Spirer Z, Feldman M. Tuftsin (an Ig-associated tetrapeptide) triggers the immunogenic function of macrophages: implications for activation of programmed cells. Proceedings of the National Academy of Sciences of the United States of America. 75: 3400-4. PMID 277940 DOI: 10.1073/Pnas.75.7.3400  0.384
1977 Amit B, Hazum E, Fridkin M, Patchornik A. A photolabile protecting group for the phenolic hydroxyl function of tyrosine. International Journal of Peptide and Protein Research. 9: 91-6. PMID 838537 DOI: 10.1002/Chin.197728348  0.335
1977 Spirer Z, Zakuth V, Bogair N, Fridkin M. Radioimmunoassay of the phagocytosis stimulating peptide tuftsin in normal and splenectomized subjects European Journal of Immunology. 7: 69-74. PMID 577481 DOI: 10.1002/Eji.1830070204  0.382
1977 Fridkin M, Stabinsky Y, Zakuth V, Spirer Z. Tuftsin and some analogs. Synthesis and interaction with human polymorphonuclear leukocytes Bba - General Subjects. 496: 203-211. PMID 576412 DOI: 10.1016/0304-4165(77)90129-5  0.353
1977 Hazum E, Fridkin M, Meidan R, Koch Y. On the role of tryptophan in luteinizing-hormone-releasing hormone (luliberin). European Journal of Biochemistry / Febs. 79: 269-73. PMID 334545 DOI: 10.1111/J.1432-1033.1977.Tb11806.X  0.315
1977 Hazum E, Fridkin M, Meidan R, Koch Y. On the function of arginine in luteinizing hormone-releasing hormone. Febs Letters. 76: 187-90. PMID 324800 DOI: 10.1016/0014-5793(77)80148-8  0.374
1977 Koch Y, Baram T, Hazum E, Fridkin M. Resistance to enzymic degradation of LH-RH analogues possessing increased biological activity. Biochemical and Biophysical Research Communications. 74: 488-91. PMID 319798 DOI: 10.1016/0006-291X(77)90330-8  0.311
1977 Fridkin M, Hazum E, Tauber-Finkelstein M, Shaltiel S. Thiolysis of O-2,4-dinitrophenyltyrosines. Spectrophotometric monitoring of the reaction and its use in peptide synthesis Archives of Biochemistry and Biophysics. 178: 517-526. PMID 13733 DOI: 10.1016/0003-9861(77)90222-3  0.354
1977 Fridkin M, Hazum E, Kalir R, Rotman M, Koch Y. Polymeric reagent synthesis of luteinizing hormone-releasing hormone - Comparison with a conventional stepwise preparation Journal of Solid-Phase Biochemistry. 2: 175-182. DOI: 10.1007/Bf02991406  0.367
1976 Shinitzky M, Hazum E, Fridkin M. Structure-activity relationships of luliberin substituted at position 8 Bba - Protein Structure. 453: 553-557. PMID 11831 DOI: 10.1016/0005-2795(76)90152-5  0.35
1975 Kalir R, Warshawsky A, Fridkin M, Patchornik A. New useful reagents for peptide synthesis. Insoluble active esters of polystyrene-bound 1-hydroxybenzotriazole. European Journal of Biochemistry / Febs. 59: 55-61. PMID 1204619 DOI: 10.1111/J.1432-1033.1975.Tb02424.X  0.35
1975 Spirer Z, Zakuth V, Golander A, Bogair N, Fridkin M. The effect of Tuftsin on the nitrous blue tetrazolium reduction of normal human polymorphonuclear leukocytes. The Journal of Clinical Investigation. 55: 198-200. PMID 1172670 DOI: 10.1172/Jci107912  0.302
1974 Kalir R, Fridkin M, Patchornik A. (4-Hydroxy-3-nitro)benzylated polystyrene. An improved polymeric nitrophenol derivative for peptide synthesis. European Journal of Biochemistry / Febs. 42: 151-6. PMID 4830188 DOI: 10.1111/J.1432-1033.1974.Tb03324.X  0.322
1974 Koch Y, Baram T, Chobsieng P, Fridkin M. Enzymic degradation of luteinizing hormone-releasing hormone (LH-RH) by hypothalamic tissue. Biochemical and Biophysical Research Communications. 61: 95-103. PMID 4613355 DOI: 10.1016/0006-291X(74)90539-7  0.311
1973 Koch Y, Wilchek M, Fridkin M, Chobsieng P, Zor U, Lindner HR. Production and characterization of an antiserum to synthetic gonadotropin-releasing hormone. Biochemical and Biophysical Research Communications. 55: 616-22. PMID 4586614 DOI: 10.1016/0006-291X(73)91188-1  0.32
1972 Fridkin M, Patchornik A, Katchalski E. Peptide synthesis by means of tert-butyloxycarbonylamino acid derivatives of poly(ethylene-co-N-hydroxymaleimide). Biochemistry. 11: 466-71. PMID 5059124 DOI: 10.1021/Bi00753A027  0.38
1970 Wilchek M, Fridkin M, Patchornik A. Nonaqueous titrimetric determination of active esters of amino acids and peptide derivatives. Analytical Chemistry. 42: 275-7. PMID 5522281 DOI: 10.1021/Ac60284A038  0.388
1970 Shaltiel S, Fridkin M. Thiolysis of dinitrophenylimidazoles and its use during synthesis of histidine peptides Biochemistry. 9: 5122-5127. PMID 5482653 DOI: 10.1021/Bi00828A013  0.394
1970 Fridkin M, Wilchek M, Sheinblatt M. NMR studies of H-D exchange of α-CH group of amino acid residues in peptides Biochemical and Biophysical Research Communications. 38: 458-464. PMID 5443693 DOI: 10.1016/0006-291X(70)90735-7  0.369
1968 Burstein Y, Fridkin M, Shinitzky M. Detection of aromatic amino acid derivatives on thin-layer chromatograms by various electron acceptors Bba - Protein Structure. 160: 141-144. PMID 5658117 DOI: 10.1016/0005-2795(68)90079-2  0.376
1966 Fridkin M, Patchornik A, Katchalski E. Use of Polymers as Chemical Reagents. I. Preparation of Peptides Journal of the American Chemical Society. 88: 3164-3165. DOI: 10.1021/Ja00965A070  0.336
1965 Fridkin M, Patchornik A, Katchalski E. A Synthesis of Cyclic Peptides Utilizing High Molecular Weight Carriers Journal of the American Chemical Society. 87: 4646-4648. DOI: 10.1021/Ja00948A047  0.359
Show low-probability matches.