Lih-Shen Chin - Publications

Biological and Biomedical Sciences Emory University, Atlanta, GA 
Molecular Biology, Neuroscience Biology, Biochemistry

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lee SM, Asress S, Hales CM, Gearing M, Vizcarra JC, Fournier CN, Gutman DA, Chin LS, Li L, Glass JD. TDP-43 cytoplasmic inclusion formation is disrupted in -associated amyotrophic lateral sclerosis/frontotemporal lobar degeneration. Brain Communications. 1: fcz014. PMID 31633109 DOI: 10.1093/braincomms/fcz014  0.32
2018 Zhang Q, Ma C, Gearing M, Wang PG, Chin LS, Li L. Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer's disease. Acta Neuropathologica Communications. 6: 19. PMID 29490708 DOI: 10.1186/s40478-018-0524-2  0.32
2017 Lee CA, Chin LS, Li L. Hypertonia-linked protein Trak1 functions with mitofusins to promote mitochondrial tethering and fusion. Protein & Cell. PMID 28924745 DOI: 10.1007/s13238-017-0469-4  0.32
2016 Chin LS, Li L. Ubiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatment. Translational Neurodegeneration. 5: 1. PMID 26740872 DOI: 10.1186/s40035-015-0049-6  0.32
2016 Lee SM, Chin LS, Li L. Dysregulation of ErbB Receptor Trafficking and Signaling in Demyelinating Charcot-Marie-Tooth Disease. Molecular Neurobiology. PMID 26732592 DOI: 10.1007/s12035-015-9668-2  0.32
2015 Yung C, Sha D, Li L, Chin LS. Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance. Molecular Neurobiology. PMID 26563499 DOI: 10.1007/s12035-015-9537-z  0.32
2015 Fallaize D, Chin LS, Li L. Differential submitochondrial localization of PINK1 as a molecular switch for mediating distinct mitochondrial signaling pathways. Cellular Signalling. PMID 26436374 DOI: 10.1016/j.cellsig.2015.09.020  0.32
2015 McKeon JE, Sha D, Li L, Chin LS. Parkin-mediated K63-polyubiquitination targets ubiquitin C-terminal hydrolase L1 for degradation by the autophagy-lysosome system. Cellular and Molecular Life Sciences : Cmls. 72: 1811-24. PMID 25403879 DOI: 10.1007/s00018-014-1781-2  0.32
2013 Chin LS, Lee SM, Li L. SIMPLE: A new regulator of endosomal trafficking and signaling in health and disease. Communicative & Integrative Biology. 6: e24214. PMID 23713142 DOI: 10.4161/cib.24214  0.32
2013 Lee SM, Sha D, Mohammed AA, Asress S, Glass JD, Chin LS, Li L. Motor and sensory neuropathy due to myelin infolding and paranodal damage in a transgenic mouse model of Charcot-Marie-Tooth disease type 1C. Human Molecular Genetics. 22: 1755-70. PMID 23359569 DOI: 10.1093/hmg/ddt022  0.32
2012 Lee SM, Chin LS, Li L. Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking. The Journal of Cell Biology. 199: 799-816. PMID 23166352 DOI: 10.1083/jcb.201204137  0.32
2012 Lee SM, Chin LS, Li L. Therapeutic implications of protein homeostasis in demyelinating peripheral neuropathies. Expert Review of Neurotherapeutics. 12: 1041-3. PMID 23039381 DOI: 10.1586/ern.12.79  0.32
2012 Hurst-Kennedy J, Chin LS, Li L. Ubiquitin C-terminal hydrolase l1 in tumorigenesis. Biochemistry Research International. 2012: 123706. PMID 22811913 DOI: 10.1155/2012/123706  0.32
2012 Lee SM, Chin LS, Li L. Protein misfolding and clearance in demyelinating peripheral neuropathies: Therapeutic implications. Communicative & Integrative Biology. 5: 107-10. PMID 22482025  0.32
2011 Lee SM, Olzmann JA, Chin LS, Li L. Mutations associated with Charcot-Marie-Tooth disease cause SIMPLE protein mislocalization and degradation by the proteasome and aggresome-autophagy pathways. Journal of Cell Science. 124: 3319-31. PMID 21896645 DOI: 10.1242/jcs.087114  0.32
2010 Chen J, Li L, Chin LS. Parkinson disease protein DJ-1 converts from a zymogen to a protease by carboxyl-terminal cleavage. Human Molecular Genetics. 19: 2395-408. PMID 20304780 DOI: 10.1093/hmg/ddq113  0.32
2010 Chin LS, Olzmann JA, Li L. Parkin-mediated ubiquitin signalling in aggresome formation and autophagy. Biochemical Society Transactions. 38: 144-9. PMID 20074049 DOI: 10.1042/BST0380144  0.32
2010 Sha D, Chin LS, Li L. Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kappaB signaling. Human Molecular Genetics. 19: 352-63. PMID 19880420 DOI: 10.1093/hmg/ddp501  0.32
2009 Giles LM, Li L, Chin LS. Printor, a novel torsinA-interacting protein implicated in dystonia pathogenesis. The Journal of Biological Chemistry. 284: 21765-75. PMID 19535332 DOI: 10.1074/jbc.M109.004838  0.32
2009 Pridgeon JW, Webber EA, Sha D, Li L, Chin LS. Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes. The Febs Journal. 276: 118-31. PMID 19019082 DOI: 10.1111/j.1742-4658.2008.06760.x  0.32
2009 Giles LM, Li L, Chin LS. TorsinA protein degradation and autophagy in DYT1 dystonia. Autophagy. 5: 82-4. PMID 18971629  0.32
2008 Whatley BR, Li L, Chin LS. The ubiquitin-proteasome system in spongiform degenerative disorders. Biochimica Et Biophysica Acta. 1782: 700-12. PMID 18790052 DOI: 10.1016/j.bbadis.2008.08.006  0.32
2008 Webber E, Li L, Chin LS. Hypertonia-associated protein Trak1 is a novel regulator of endosome-to-lysosome trafficking. Journal of Molecular Biology. 382: 638-51. PMID 18675823 DOI: 10.1016/j.jmb.2008.07.045  0.32
2008 Giles LM, Chen J, Li L, Chin LS. Dystonia-associated mutations cause premature degradation of torsinA protein and cell-type-specific mislocalization to the nuclear envelope. Human Molecular Genetics. 17: 2712-22. PMID 18552369 DOI: 10.1093/hmg/ddn173  0.32
2008 Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, ... ... Chin LS, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 4: 151-75. PMID 18188003  0.32
2008 Lee JT, Wheeler TC, Li L, Chin LS. Ubiquitination of alpha-synuclein by Siah-1 promotes alpha-synuclein aggregation and apoptotic cell death. Human Molecular Genetics. 17: 906-17. PMID 18065497 DOI: 10.1093/hmg/ddm363  0.32
2007 Djukic B, Casper KB, Philpot BD, Chin LS, McCarthy KD. Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11354-65. PMID 17942730 DOI: 10.1523/JNEUROSCI.0723-07.2007  0.32
2007 Olzmann JA, Li L, Chudaev MV, Chen J, Perez FA, Palmiter RD, Chin LS. Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. The Journal of Cell Biology. 178: 1025-38. PMID 17846173 DOI: 10.1083/jcb.200611128  0.32
2007 Pridgeon JW, Olzmann JA, Chin LS, Li L. PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. Plos Biology. 5: e172. PMID 17579517 DOI: 10.1371/journal.pbio.0050172  0.32
2007 Kim BY, Olzmann JA, Barsh GS, Chin LS, Li L. Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking. Molecular Biology of the Cell. 18: 1129-42. PMID 17229889 DOI: 10.1091/mbc.E06-09-0787  0.32
2007 Olzmann JA, Bordelon JR, Muly EC, Rees HD, Levey AI, Li L, Chin LS. Selective enrichment of DJ-1 protein in primate striatal neuronal processes: implications for Parkinson's disease. The Journal of Comparative Neurology. 500: 585-99. PMID 17120294 DOI: 10.1002/cne.21191  0.32
2006 Kirk E, Chin LS, Li L. GRIF1 binds Hrs and is a new regulator of endosomal trafficking. Journal of Cell Science. 119: 4689-701. PMID 17062640 DOI: 10.1242/jcs.03249  0.32
2006 Choi J, Sullards MC, Olzmann JA, Rees HD, Weintraub ST, Bostwick DE, Gearing M, Levey AI, Chin LS, Li L. Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases. The Journal of Biological Chemistry. 281: 10816-24. PMID 16517609 DOI: 10.1074/jbc.M509079200  0.32
2005 Choi J, Rees HD, Weintraub ST, Levey AI, Chin LS, Li L. Oxidative modifications and aggregation of Cu,Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases. The Journal of Biological Chemistry. 280: 11648-55. PMID 15659387 DOI: 10.1074/jbc.M414327200  0.32
2004 Choi J, Levey AI, Weintraub ST, Rees HD, Gearing M, Chin LS, Li L. Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases. The Journal of Biological Chemistry. 279: 13256-64. PMID 14722078 DOI: 10.1074/jbc.M314124200  0.32
2004 Olzmann JA, Brown K, Wilkinson KD, Rees HD, Huai Q, Ke H, Levey AI, Li L, Chin LS. Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function. The Journal of Biological Chemistry. 279: 8506-15. PMID 14665635 DOI: 10.1074/jbc.M311017200  0.32
2003 Huai Q, Sun Y, Wang H, Chin LS, Li L, Robinson H, Ke H. Crystal structure of DJ-1/RS and implication on familial Parkinson's disease. Febs Letters. 549: 171-5. PMID 12914946  0.32
2002 Chin LS, Vavalle JP, Li L. Staring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradation. The Journal of Biological Chemistry. 277: 35071-9. PMID 12121982 DOI: 10.1074/jbc.M203300200  0.32
2002 Li Y, Chin LS, Levey AI, Li L. Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking. The Journal of Biological Chemistry. 277: 28212-21. PMID 12021262 DOI: 10.1074/jbc.M111612200  0.32
2002 Wheeler TC, Chin LS, Li Y, Roudabush FL, Li L. Regulation of synaptophysin degradation by mammalian homologues of seven in absentia. The Journal of Biological Chemistry. 277: 10273-82. PMID 11786535 DOI: 10.1074/jbc.M107857200  0.32
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