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Mirvat El-Sibai, Ph.D. - Publications

Affiliations: 
2007 Yeshiva University, New York, NY, United States 
Area:
Cell Biology
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54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Abdellatef S, Fakhoury I, Haddad MA, Jaafar L, Maalouf H, Hanna S, Khalil B, El Masri Z, Hodgson L, El-Sibai M. StarD13 negatively regulates invadopodia formation and invasion in high-grade serous (HGS) ovarian adenocarcinoma cells by inhibiting Cdc42. European Journal of Cell Biology. 101: 151197. PMID 34958986 DOI: 10.1016/j.ejcb.2021.151197  0.36
2021 El-Sibai M, El Hajj J, Al Haddad M, El Baba N, Al Saneh M, Daoud Khatoun W, Helaers R, Vikkula M, El Atat O, Sabbagh J, Abou Chebel N, Ghassibe-Sabbagh M. Dysregulation of Rho GTPases in orofacial cleft patients-derived primary cells leads to impaired cell migration, a potential cause of cleft/lip palate development. Cells & Development. 165: 203656. PMID 34024335 DOI: 10.1016/j.cdev.2021.203656  0.308
2021 Ghassibe-Sabbagh M, El Hajj J, Al Saneh M, El Baba N, Abou Issa J, Al Haddad M, El Atat O, Sabbagh J, Abou Chebel N, El-Sibai M. Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of Rho GTPases in cleft/lip palate development. Cells & Development. 166: 203674. PMID 33994351 DOI: 10.1016/j.cdev.2021.203674  0.309
2021 El-Chami D, Al Haddad M, Abi-Habib R, El-Sibai M. Recombinant anthrax lethal toxin inhibits cell motility and invasion in breast cancer cells through the dysregulation of Rho GTPases. Oncology Letters. 21: 163. PMID 33552281 DOI: 10.3892/ol.2020.12424  0.32
2021 El-Mais N, Fakhoury I, Abdellatef S, Abi-Habib R, El-Sibai M. Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits ovarian cancer cell adhesion and migration through autophagy-mediated inhibition of RhoA. Journal of Ovarian Research. 14: 13. PMID 33423701 DOI: 10.1186/s13048-021-00767-3  0.355
2020 Swayden M, Bekdash A, Fakhoury I, El-Atat O, Borjac-Natour J, El-Sibai M, Abi-Habib RJ. Activation of autophagy following [HuArgI (Co)-PEG5000]-induced arginine deprivation mediates cell death in colon cancer cells. Human Cell. PMID 32979152 DOI: 10.1007/s13577-020-00437-4  0.321
2020 Al Haddad M, El-Rif R, Hanna S, Jaafar L, Dennaoui R, Abdellatef S, Miskolci V, Cox D, Hodgson L, El-Sibai M. Differential regulation of rho GTPases during lung adenocarcinoma migration and invasion reveals a novel role of the tumor suppressor StarD13 in invadopodia regulation. Cell Communication and Signaling : Ccs. 18: 144. PMID 32900380 DOI: 10.1186/S12964-020-00635-5  0.373
2020 Salloum G, Jaafar L, El-Sibai M. Rho A and Rac1: Antagonists moving forward. Tissue & Cell. 65: 101364. PMID 32746999 DOI: 10.1016/J.Tice.2020.101364  0.434
2020 Al-Koussa H, El Mais N, Maalouf H, Abi-Habib R, El-Sibai M. Arginine deprivation: a potential therapeutic for cancer cell metastasis? A review. Cancer Cell International. 20: 150. PMID 32390765 DOI: 10.1186/S12935-020-01232-9  0.335
2020 El Baba N, Farran M, Khalil EA, Jaafar L, Fakhoury I, El-Sibai M. The Role of Rho GTPases in VEGF Signaling in Cancer Cells. Analytical Cellular Pathology (Amsterdam). 2020: 2097214. PMID 32377503 DOI: 10.1155/2020/2097214  0.327
2020 Jaafar L, Chamseddine Z, El-Sibai M. StarD13: a potential star target for tumor therapeutics. Human Cell. PMID 32274657 DOI: 10.1007/S13577-020-00358-2  0.33
2020 Al-Koussa H, Atat OE, Jaafar L, Tashjian H, El-Sibai M. The Role of Rho GTPases in Motility and Invasion of Glioblastoma Cells. Analytical Cellular Pathology (Amsterdam). 2020: 9274016. PMID 32089990 DOI: 10.1155/2020/9274016  0.413
2019 Al-Koussa H, Al-Haddad M, Abi-Habib R, El-Sibai M. Human Recombinant Arginase I [HuArgI (Co)-PEG5000]-Induced Arginine Depletion Inhibits Colorectal Cancer Cell Migration and Invasion. International Journal of Molecular Sciences. 20. PMID 31795337 DOI: 10.3390/Ijms20236018  0.349
2019 Nicolas S, Abdellatef S, Haddad MA, Fakhoury I, El-Sibai M. Hypoxia and EGF Stimulation Regulate VEGF Expression in Human Glioblastoma Multiforme (GBM) Cells by Differential Regulation of the PI3K/Rho-GTPase and MAPK Pathways. Cells. 8. PMID 31698752 DOI: 10.3390/Cells8111397  0.381
2019 Daaboul HE, Dagher C, Taleb RI, Bodman-Smith K, Shebaby WN, El-Sibai M, Mroueh MA, Daher CF. β-2-Himachalen-6-ol inhibits 4T1 cells-induced metastatic triple negative breast carcinoma in murine model. Chemico-Biological Interactions. 309: 108703. PMID 31194954 DOI: 10.1016/J.Cbi.2019.06.016  0.42
2019 Nasreddine G, El-Sibai M, Abi-Habib RJ. Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent. Investigational New Drugs. PMID 30887252 DOI: 10.1007/S10637-019-00756-W  0.43
2019 Fostok S, El-Sibai M, Bazzoun D, Lelièvre S, Talhouk R. Connexin 43 Loss Triggers Cell Cycle Entry and Invasion in Non-Neoplastic Breast Epithelium: A Role for Noncanonical Wnt Signaling. Cancers. 11. PMID 30857262 DOI: 10.3390/Cancers11030339  0.414
2019 El Atat O, Fakih A, El-Sibai M. RHOG Activates RAC1 through CDC42 Leading to Tube Formation in Vascular Endothelial Cells. Cells. 8. PMID 30781697 DOI: 10.3390/Cells8020171  0.464
2018 Fostok SF, El-Sibai M, El-Sabban M, Talhouk RS. Gap Junctions and Wnt Signaling in the Mammary Gland: a Cross-Talk? Journal of Mammary Gland Biology and Neoplasia. PMID 30194659 DOI: 10.1007/S10911-018-9411-5  0.307
2018 Al Hassan M, Fakhoury I, El Masri Z, Ghazale N, Dennaoui R, El Atat O, Kanaan A, El-Sibai M. Metformin Treatment Inhibits Motility and Invasion of Glioblastoma Cancer Cells. Analytical Cellular Pathology (Amsterdam). 2018: 5917470. PMID 30046513 DOI: 10.1155/2018/5917470  0.416
2018 Daaboul HE, Dagher C, Taleb RI, Bodman-Smith K, Shebaby WN, El-Sibai M, Mroueh MA, Daher CF. The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 103: 443-452. PMID 29674280 DOI: 10.1016/J.Biopha.2018.04.027  0.377
2018 Fostok SF, Bazzoun D, Lelievre SA, El-Sibai M, Talhouk RS. Abstract 4505: Silencing connexin 43 induces cell cycle entry and invasion in non-neoplastic mammary epithelial cells Cancer Research. 78: 4505-4505. DOI: 10.1158/1538-7445.Am2018-4505  0.424
2017 Daaboul HE, Daher CF, Taleb RI, Boulos J, Bodman-Smith K, Boukamp P, Shebaby WN, Dagher C, El-Sibai M, Mroueh MA. β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo. The Journal of Pharmacy and Pharmacology. PMID 28872682 DOI: 10.1111/Jphp.12796  0.37
2017 Daaboul HE, Daher CF, Bodman-Smith K, Taleb RI, Shebaby WN, Boulos J, Dagher C, Mroueh MA, El-Sibai M. Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways. Chemico-Biological Interactions. PMID 28782499 DOI: 10.1016/J.Cbi.2017.08.003  0.434
2017 Shebaby WN, Mroueh MA, Boukamp P, Ri RI, Bodman-Smith K, El-Sibai M, Daher CF. Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer. Bmc Complementary and Alternative Medicine. 17: 36. PMID 28073348 DOI: 10.1186/S12906-016-1531-0  0.311
2016 Taleb RI, Najm P, Shebaby W, Boulos JC, Demirdjian S, Hariri E, El-Sibai M, Daher C, Mroueh M. β-2-Himachalen-6-ol: A Novel Anticancer Sesquiterepene Unique to the Lebanese Wild Carrot. Journal of Ethnopharmacology. PMID 27240746 DOI: 10.1016/J.Jep.2016.05.053  0.372
2016 Al-Dimassi S, Salloum G, Saykali B, Khoury O, Liu S, Leppla SH, Abi-Habib R, El-Sibai M. Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion. International Journal of Oncology. PMID 26984023 DOI: 10.3892/Ijo.2016.3431  0.486
2016 Boulos J, Abi-Habib R, El-Sibai M, Shebaby W, Daher C, Taleb R, Mroueh M. A new sesquiterpene from Lebanese wild carrot inhibits proliferation of human acute myeloid leukemia cells Planta Medica. 81: S1-S381. DOI: 10.1055/S-0036-1596492  0.36
2015 Shebaby WN, Bodman-Smith KB, Mansour A, Mroueh M, Taleb RI, El-Sibai M, Daher CF. Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways. Journal of Medicinal Food. 18: 745-52. PMID 25599142 DOI: 10.1089/Jmf.2014.3225  0.38
2015 Khoury O, Ghazale N, Stone E, El-Sibai M, Frankel AE, Abi-Habib RJ. Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells. Journal of Neuro-Oncology. 122: 75-85. PMID 25567351 DOI: 10.1016/S0959-8049(14)50671-5  0.418
2014 Zgheib P, Daher CF, Mroueh M, Nasrallah A, Taleb RI, El-Sibai M. Daucus carota Pentane/Diethyl Ether Fraction Inhibits Motility and Reduces Invasion of Cancer Cells. Chemotherapy. 60: 302-9. PMID 26088465 DOI: 10.1159/000430085  0.412
2014 Shebaby WN, Mroueh M, Bodman-Smith K, Mansour A, Taleb RI, Daher CF, El-Sibai M. Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells. Bmc Complementary and Alternative Medicine. 14: 387. PMID 25300932 DOI: 10.1186/1472-6882-14-387  0.411
2014 Khoury N, El-Hayek S, Tarras O, El-Sabban M, El-Sibai M, Rizk S. Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion. International Journal of Oncology. 45: 2117-27. PMID 25189203 DOI: 10.3892/Ijo.2014.2635  0.459
2014 Saykali BA, El-Sibai M. Invadopodia, regulation, and assembly in cancer cell invasion. Cell Communication & Adhesion. 21: 207-12. PMID 24930891 DOI: 10.3109/15419061.2014.923845  0.384
2014 Hanna S, Khalil B, Nasrallah A, Saykali BA, Sobh R, Nasser S, El-Sibai M. StarD13 is a tumor suppressor in breast cancer that regulates cell motility and invasion International Journal of Oncology. 44: 1499-1511. PMID 24627003 DOI: 10.3892/Ijo.2014.2330  0.399
2014 Najm P, El-Sibai M. Palladin regulation of the actin structures needed for cancer invasion. Cell Adhesion & Migration. 8: 29-35. PMID 24525547 DOI: 10.4161/Cam.28024  0.443
2014 Khalil BD, Hanna S, Saykali BA, El-Sitt S, Nasrallah A, Marston D, El-Sabban M, Hahn KM, Symons M, El-Sibai M. The regulation of RhoA at focal adhesions by StarD13 is important for astrocytoma cell motility. Experimental Cell Research. 321: 109-22. PMID 24333506 DOI: 10.1016/J.Yexcr.2013.11.023  0.483
2014 Nasrallah A, Saykali B, Al Dimassi S, Khoury N, Hanna S, El-Sibai M. Effect of StarD13 on colorectal cancer proliferation, motility and invasion Oncology Reports. 31: 505-515. PMID 24253896 DOI: 10.3892/Or.2013.2861  0.455
2013 Hanna S, El-Sibai M. Signaling networks of Rho GTPases in cell motility Cellular Signalling. 25: 1955-1961. PMID 23669310 DOI: 10.1016/J.Cellsig.2013.04.009  0.383
2013 El-Sitt S, El-Sibai M. The STAR of the DLC family. Journal of Receptor and Signal Transduction Research. 33: 10-3. PMID 23316797 DOI: 10.3109/10799893.2012.752002  0.319
2013 Shebaby WN, El-Sibai M, Smith KB, Karam MC, Mroueh M, Daher CF. The antioxidant and anticancer effects of wild carrot oil extract. Phytotherapy Research : Ptr. 27: 737-44. PMID 22815230 DOI: 10.1002/Ptr.4776  0.348
2013 Mroueh M, Shebaby W, Smith K, Karam M, Mansour A, El Asmar M, El-Sibai M, Daher C. The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis Planta Medica. 79. DOI: 10.1055/S-0033-1352409  0.347
2012 El-Sitt S, Khalil BD, Hanna S, El-Sabban M, Fakhreddine N, El-Sibai M. DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma. Oncology Reports. 28: 511-8. PMID 22614672 DOI: 10.3892/Or.2012.1819  0.342
2012 Khalil BD, El-Sibai M. Rho GTPases in primary brain tumor malignancy and invasion. Journal of Neuro-Oncology. 108: 333-9. PMID 22528793 DOI: 10.1007/S11060-012-0866-8  0.335
2012 Bahnan W, Koussa J, Younes S, Abi Rizk M, Khalil B, El Sitt S, Hanna S, El-Sibai M, Khalaf RA. Deletion of the Candida albicans PIR32 results in increased virulence, stress response, and upregulation of cell wall chitin deposition. Mycopathologia. 174: 107-19. PMID 22391823 DOI: 10.1007/S11046-012-9533-Z  0.368
2012 Taleb R, Chababi W, El-Sibai M, Daher C, Mroueh M. Analysis of the pentane fraction obtained from Daucus carota oil extract and its activity against colon cancer cell lines Planta Medica. 78. DOI: 10.1055/S-0032-1320834  0.331
2009 Wu H, Shekar SC, Flinn RJ, El-Sibai M, Jaiswal BS, Sen KI, Janakiraman V, Seshagiri S, Gerfen GJ, Girvin ME, Backer JM. Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110alpha and are disrupted in oncogenic p85 mutants. Proceedings of the National Academy of Sciences of the United States of America. 106: 20258-63. PMID 19915146 DOI: 10.1073/Pnas.0902369106  0.66
2008 Sarmiento C, Wang W, Dovas A, Yamaguchi H, Sidani M, El-Sibai M, Desmarais V, Holman HA, Kitchen S, Backer JM, Alberts A, Condeelis J. WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells. The Journal of Cell Biology. 180: 1245-60. PMID 18362183 DOI: 10.1083/Jcb.200708123  0.613
2008 El-Sibai M, Pertz O, Pang H, Yip SC, Lorenz M, Symons M, Condeelis JS, Hahn KM, Backer JM. RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells. Experimental Cell Research. 314: 1540-52. PMID 18316075 DOI: 10.1016/J.Yexcr.2008.01.016  0.657
2007 Sidani M, Wessels D, Mouneimne G, Ghosh M, Goswami S, Sarmiento C, Wang W, Kuhl S, El-Sibai M, Backer JM, Eddy R, Soll D, Condeelis J. Cofilin determines the migration behavior and turning frequency of metastatic cancer cells. The Journal of Cell Biology. 179: 777-91. PMID 18025308 DOI: 10.1083/Jcb.200707009  0.614
2007 El-Sibai M, Nalbant P, Pang H, Flinn RJ, Sarmiento C, Macaluso F, Cammer M, Condeelis JS, Hahn KM, Backer JM. Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells. Journal of Cell Science. 120: 3465-74. PMID 17855387 DOI: 10.1242/Jcs.005942  0.702
2007 Yip SC, El-Sibai M, Coniglio SJ, Mouneimne G, Eddy RJ, Drees BE, Neilsen PO, Goswami S, Symons M, Condeelis JS, Backer JM. The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration. Journal of Cell Science. 120: 3138-46. PMID 17698922 DOI: 10.1242/Jcs.005298  0.607
2007 El-Sibai M, Backer JM. Phospholipase C gamma negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells. European Journal of Immunology. 37: 261-70. PMID 17163445 DOI: 10.1002/Eji.200635875  0.569
2004 Yip SC, El-Sibai M, Hill KM, Wu H, Fu Z, Condeelis JS, Backer JM. Over-expression of the p110beta but not p110alpha isoform of PI 3-kinase inhibits motility in breast cancer cells. Cell Motility and the Cytoskeleton. 59: 180-8. PMID 15468162 DOI: 10.1002/Cm.20032  0.649
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