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Jeremiah D. Farelli, Ph.D. - Publications

Affiliations: 
2010 Boston University, Boston, MA, United States 
Area:
General Biophysics, Microbiology Biology, Molecular Biology
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12/17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Huang H, Pandya C, Liu C, Al-Obaidi NF, Wang M, Zheng L, Toews Keating S, Aono M, Love JD, Evans B, Seidel RD, Hillerich BS, Garforth SJ, Almo SC, Mariano PS, ... ... Farelli JD, et al. Panoramic view of a superfamily of phosphatases through substrate profiling. Proceedings of the National Academy of Sciences of the United States of America. 112: E1974-83. PMID 25848029 DOI: 10.1073/Pnas.1423570112  0.424
2015 London N, Farelli JD, Brown SD, Liu C, Huang H, Korczynska M, Al-Obaidi NF, Babbitt PC, Almo SC, Allen KN, Shoichet BK. Covalent docking predicts substrates for haloalkanoate dehalogenase superfamily phosphatases. Biochemistry. 54: 528-37. PMID 25513739 DOI: 10.1021/Bi501140K  0.34
2014 Pandya C, Farelli JD, Dunaway-Mariano D, Allen KN. Enzyme promiscuity: engine of evolutionary innovation. The Journal of Biological Chemistry. 289: 30229-36. PMID 25210039 DOI: 10.1074/Jbc.R114.572990  0.341
2014 Wu R, Latham JA, Chen D, Farelli J, Zhao H, Matthews K, Allen KN, Dunaway-Mariano D. Structure and catalysis in the Escherichia coli hotdog-fold thioesterase paralogs YdiI and YbdB. Biochemistry. 53: 4788-805. PMID 25010423 DOI: 10.1021/Bi500334V  0.464
2014 Farelli JD, Galvin BD, Li Z, Liu C, Aono M, Garland M, Hallett OE, Causey TB, Ali-Reynolds A, Saltzberg DJ, Carlow CK, Dunaway-Mariano D, Allen KN. Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs. Plos Pathogens. 10: e1004245. PMID 24992307 DOI: 10.1371/Journal.Ppat.1004245  0.524
2014 Barelier S, Cummings JA, Rauwerdink AM, Hitchcock DS, Farelli JD, Almo SC, Raushel FM, Allen KN, Shoichet BK. Substrate deconstruction and the nonadditivity of enzyme recognition. Journal of the American Chemical Society. 136: 7374-82. PMID 24791931 DOI: 10.1021/Ja501354Q  0.356
2013 Farelli JD, Gumbart JC, Akey IV, Hempstead A, Amyot W, Head JF, McKnight CJ, Isberg RR, Akey CW. IcmQ in the Type 4b secretion system contains an NAD+ binding domain. Structure (London, England : 1993). 21: 1361-73. PMID 23850453 DOI: 10.1016/J.Str.2013.05.017  0.622
2012 Chen D, Latham J, Zhao H, Bisoffi M, Farelli J, Dunaway-Mariano D. Human brown fat inducible thioesterase variant 2 cellular localization and catalytic function. Biochemistry. 51: 6990-9. PMID 22897136 DOI: 10.1021/Bi3008824  0.461
2012 Brown JW, Farelli JD, McKnight CJ. On the unyielding hydrophobic core of villin headpiece. Protein Science : a Publication of the Protein Society. 21: 647-54. PMID 22467489 DOI: 10.1002/Pro.2048  0.424
2011 Brown JW, Farelli JD, McKnight CJ. On unsatisfied hydrogen bonds in the N-terminal subdomain of villin headpiece. Journal of Molecular Biology. 413: 543-7. PMID 21903098 DOI: 10.1016/J.Jmb.2011.08.024  0.395
2011 Huang H, Patskovsky Y, Toro R, Farelli JD, Pandya C, Almo SC, Allen KN, Dunaway-Mariano D. Divergence of structure and function in the haloacid dehalogenase enzyme superfamily: Bacteroides thetaiotaomicron BT2127 is an inorganic pyrophosphatase. Biochemistry. 50: 8937-49. PMID 21894910 DOI: 10.1021/Bi201181Q  0.499
2009 Raychaudhury S, Farelli JD, Montminy TP, Matthews M, Ménétret JF, Duménil G, Roy CR, Head JF, Isberg RR, Akey CW. Structure and function of interacting IcmR-IcmQ domains from a type IVb secretion system in Legionella pneumophila. Structure (London, England : 1993). 17: 590-601. PMID 19368892 DOI: 10.1016/J.Str.2009.02.011  0.538
Low-probability matches (unlikely to be authored by this person)
2018 Farelli JD, Asrani KH, Isaacs C, deBear JS, Stahley MR, Shah A, Lasaro MA, Cheng CJ, Subramanian RR. Leveraging Rational Protein Engineering to Improve mRNA Therapeutics. Nucleic Acid Therapeutics. PMID 29437538 DOI: 10.1089/Nat.2017.0697  0.269
2018 Asrani KH, Farelli JD, Stahley MR, Miller RL, Cheng CJ, Subramanian RR, Brown JM. Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA. Rna Biology. 1-7. PMID 29578372 DOI: 10.1080/15476286.2018.1450054  0.25
2018 Roseman DS, Khan T, Rajas F, Jun LS, Asrani KH, Isaacs C, Farelli JD, Subramanian RR. G6PC mRNA Therapy Positively Regulates Fasting Blood Glucose and Decreases Liver Abnormalities in a Mouse Model of Glycogen Storage Disease 1a. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29428299 DOI: 10.1016/J.Ymthe.2018.01.006  0.248
2017 Koo BM, Kritikos G, Farelli JD, Todor H, Tong K, Kimsey H, Wapinski I, Galardini M, Cabal A, Peters JM, Hachmann AB, Rudner DZ, Allen KN, Typas A, Gross CA. Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis. Cell Systems. PMID 28189581 DOI: 10.1016/J.Cels.2016.12.013  0.237
2009 Piper BJ, Farelli JD, Meyer JS. Dissociation between serotonin neurotoxicity and brain-derived neurotrophic factor induction following neonatal MDMA exposure in rats. Developmental Neuroscience. 31: 90-4. PMID 19372690 DOI: 10.1159/000207497  0.215
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