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Arvin B. Tam, Ph.D. - Publications

Affiliations: 
2011 Biology University of California, San Diego, La Jolla, CA 
Area:
Cell Biology, Molecular Biology, Biochemistry
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tam AB, Roberts LS, Chandra V, Rivera IG, Nomura DK, Forbes DJ, Niwa M. The UPR Activator ATF6 Responds to Proteotoxic and Lipotoxic Stress by Distinct Mechanisms. Developmental Cell. 46: 327-343.e7. PMID 30086303 DOI: 10.1016/J.Devcel.2018.04.023  0.566
2017 Miller M, Tam AB, Mueller JL, Rosenthal P, Beppu A, Gordillo R, McGeough MD, Vuong C, Doherty TA, Hoffman HM, Niwa M, Broide DH. Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate. Journal of Immunology (Baltimore, Md. : 1950). PMID 28275141 DOI: 10.4049/Jimmunol.1601848  0.531
2016 Jiang D, Lynch C, Medeiros BC, Liedtke M, Bam R, Tam AB, Yang Z, Alagappan M, Abidi P, Le QT, Giaccia AJ, Denko NC, Niwa M, Koong AC. Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response. Scientific Reports. 6: 33353. PMID 27634301 DOI: 10.1038/Srep33353  0.58
2016 Jiang D, Tam A, Alagappan M, Hay MP, Gupta A, Kozak M, Solow-Cordero DE, Lum PY, Denko N, Giaccia AJ, Le QT, Niwa M, Koong AC. Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Cytotoxic to Human Multiple Myeloma. Molecular Cancer Therapeutics. PMID 27307600 DOI: 10.1158/1535-7163.Mct-15-1023  0.52
2014 Tam AB, Koong AC, Niwa M. Ire1 has distinct catalytic mechanisms for XBP1/HAC1 splicing and RIDD. Cell Reports. 9: 850-8. PMID 25437541 DOI: 10.1016/J.Celrep.2014.09.016  0.55
2014 Miller M, Rosenthal P, Beppu A, Mueller JL, Hoffman HM, Tam AB, Doherty TA, McGeough MD, Pena CA, Suzukawa M, Niwa M, Broide DH. ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma. Journal of Immunology (Baltimore, Md. : 1950). 192: 3475-87. PMID 24623133 DOI: 10.4049/Jimmunol.1303047  0.527
2012 Tam AB, Mercado EL, Hoffmann A, Niwa M. ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK. Plos One. 7: e45078. PMID 23110043 DOI: 10.1371/Journal.Pone.0045078  0.574
2012 Miller M, Tam AB, Cho JY, Doherty TA, Pham A, Khorram N, Rosenthal P, Mueller JL, Hoffman HM, Suzukawa M, Niwa M, Broide DH. ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6. Proceedings of the National Academy of Sciences of the United States of America. 109: 16648-53. PMID 23011799 DOI: 10.1073/Pnas.1204151109  0.573
2011 Papandreou I, Denko NC, Olson M, Van Melckebeke H, Lust S, Tam A, Solow-Cordero DE, Bouley DM, Offner F, Niwa M, Koong AC. Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma. Blood. 117: 1311-4. PMID 21081713 DOI: 10.1182/Blood-2010-08-303099  0.576
2006 DuRose JB, Tam AB, Niwa M. Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress. Molecular Biology of the Cell. 17: 3095-107. PMID 16672378 DOI: 10.1091/Mbc.E06-01-0055  0.532
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