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Srinivas Somarowthu, Ph.D. - Publications

Affiliations: 
2011 Chemistry Northeastern University, Boston, MA, United States 
Area:
Physical Chemistry, Biochemistry, Bioinformatics Biology
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Yankey A, Clark SC, Owens MC, Somarowthu S. Purification and Structural Characterization of the Long Noncoding RNAs. Methods in Molecular Biology (Clifton, N.J.). 2372: 93-110. PMID 34417746 DOI: 10.1007/978-1-0716-1697-0_10  0.328
2020 Mazina OM, Somarowthu S, Kadyrova LY, Baranovskiy AG, Tahirov TH, Kadyrov FA, Mazin AV. Replication protein A binds RNA and promotes R-loop formation. The Journal of Biological Chemistry. PMID 32796030 DOI: 10.1074/Jbc.Ra120.013812  0.377
2020 Manigrasso J, Chillón I, Genna V, Vidossich P, Somarowthu S, Pyle AM, De Vivo M, Marcia M. Visualizing group II intron dynamics between the first and second steps of splicing. Nature Communications. 11: 2837. PMID 32503992 DOI: 10.1038/S41467-020-16741-4  0.438
2019 Owens MC, Clark SC, Yankey A, Somarowthu S. Identifying Structural Domains and Conserved Regions in the Long Non-Coding RNA lncTCF7. International Journal of Molecular Sciences. 20. PMID 31561429 DOI: 10.3390/Ijms20194770  0.434
2019 Tavares RCA, Pyle AM, Somarowthu S. Phylogenetic Analysis with Improved Parameters Reveals Conservation in lncRNA Structures. Journal of Molecular Biology. PMID 30890332 DOI: 10.1016/J.Jmb.2019.03.012  0.447
2017 Liu F, Somarowthu S, Pyle AM. Visualizing the secondary and tertiary architectural domains of lncRNA RepA. Nature Chemical Biology. PMID 28068310 DOI: 10.1038/Nchembio.2272  0.43
2016 Somarowthu S. Progress and Current Challenges in Modeling Large RNAs. Journal of Molecular Biology. 428: 736-47. PMID 26585404 DOI: 10.1016/J.Jmb.2015.11.011  0.468
2016 Chillon I, Somarowthu S, Liu F, Pyle AM. Abstract IA25: Regulatory control of lincRNA function through formation of complex RNA structural motifs Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-Ia25  0.439
2015 Chillón I, Marcia M, Legiewicz M, Liu F, Somarowthu S, Pyle AM. Native Purification and Analysis of Long RNAs. Methods in Enzymology. 558: 3-37. PMID 26068736 DOI: 10.1016/Bs.Mie.2015.01.008  0.383
2015 Somarowthu S, Legiewicz M, Chillón I, Marcia M, Liu F, Pyle AM. HOTAIR forms an intricate and modular secondary structure. Molecular Cell. 58: 353-61. PMID 25866246 DOI: 10.1016/J.Molcel.2015.03.006  0.497
2015 Brodkin HR, DeLateur NA, Somarowthu S, Mills CL, Novak WR, Beuning PJ, Ringe D, Ondrechen MJ. Prediction of distal residue participation in enzyme catalysis. Protein Science : a Publication of the Protein Society. 24: 762-78. PMID 25627867 DOI: 10.1002/Pro.2648  0.583
2014 Somarowthu S, Legiewicz M, Keating KS, Pyle AM. Visualizing the ai5γ group IIB intron. Nucleic Acids Research. 42: 1947-58. PMID 24203709 DOI: 10.1093/Nar/Gkt1051  0.439
2013 Marcia M, Humphris-Narayanan E, Keating KS, Somarowthu S, Rajashankar K, Pyle AM. Solving nucleic acid structures by molecular replacement: examples from group II intron studies. Acta Crystallographica. Section D, Biological Crystallography. 69: 2174-85. PMID 24189228 DOI: 10.1107/S0907444913013218  0.354
2013 Marcia M, Somarowthu S, Pyle AM. Now on display: a gallery of group II intron structures at different stages of catalysis. Mobile Dna. 4: 14. PMID 23634971 DOI: 10.1186/1759-8753-4-14  0.368
2013 Wang Z, Yin P, Lee JS, Parasuram R, Somarowthu S, Ondrechen MJ. Protein function annotation with Structurally Aligned Local Sites of Activity (SALSAs). Bmc Bioinformatics. 14: S13. PMID 23514271 DOI: 10.1186/1471-2105-14-S3-S13  0.524
2012 Somarowthu S, Ondrechen MJ. POOL server: machine learning application for functional site prediction in proteins. Bioinformatics (Oxford, England). 28: 2078-9. PMID 22661648 DOI: 10.1093/Bioinformatics/Bts321  0.46
2011 Somarowthu S, Brodkin HR, DAquino JA, Ringe D, Ondrechen MJ, Beuning PJ. A tale of two isomerases: Compact versus extended active sites in ketosteroid isomerase and phosphoglucose isomerase Biochemistry. 50: 9283-9295. PMID 21970785 DOI: 10.1021/Bi201089V  0.593
2011 Han GW, Ko J, Farr CL, Deller MC, Xu Q, Chiu HJ, Miller MD, Sefcikova J, Somarowthu S, Beuning PJ, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Wilson IA, et al. Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity. Proteins. 79: 2146-60. PMID 21538547 DOI: 10.1002/Prot.23035  0.589
2011 Somarowthu S, Yang H, Hildebrand DG, Ondrechen MJ. High-performance prediction of functional residues in proteins with machine learning and computed input features. Biopolymers. 95: 390-400. PMID 21254002 DOI: 10.1002/Bip.21589  0.468
2010 Parasuram R, Lee JS, Yin P, Somarowthu S, Ondrechen MJ. Functional classification of protein 3D structures from predicted local interaction sites. Journal of Bioinformatics and Computational Biology. 8: 1-15. PMID 21155016 DOI: 10.1142/S0219720010005166  0.511
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