Bradley R. Cairns - Publications

Oncological Sciences University of Utah, Salt Lake City, UT 
Molecular Biology, Biochemistry

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.


Year Citation  Score
2021 Shi J, Zhang Y, Tan D, Zhang X, Yan M, Zhang Y, Franklin R, Shahbazi M, Mackinlay K, Liu S, Kuhle B, James ER, Zhang L, Qu Y, Zhai Q, ... ... Cairns BR, et al. PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications. Nature Cell Biology. PMID 33820973 DOI: 10.1038/s41556-021-00652-7  0.64
2021 Guo J, Sosa E, Chitiashvili T, Nie X, Rojas EJ, Oliver E, Plath K, Hotaling JM, Stukenborg JB, Clark AT, Cairns BR. Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment. Cell Stem Cell. PMID 33453151 DOI: 10.1016/j.stem.2020.12.004  0.4
2020 Clapier CR, Verma N, Parnell TJ, Cairns BR. Cancer-Associated Gain-of-Function Mutations Activate a SWI/SNF-Family Regulatory Hub. Molecular Cell. PMID 33058778 DOI: 10.1016/j.molcel.2020.09.024  0.56
2020 Murphy PJ, Guo J, Jenkins TG, James ER, Hoidal JR, Huecksteadt T, Broberg DS, Hotaling JM, Alonso DF, Carrell DT, Cairns BR, Aston KI. NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure. Plos Genetics. 16: e1008756. PMID 32520939 DOI: 10.1371/journal.pgen.1008756  0.4
2020 Schlichter A, Kasten MM, Parnell TJ, Cairns BR. Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes. Elife. 9. PMID 32496195 DOI: 10.7554/eLife.58130  0.48
2020 Gambini A, Stein P, Savy V, Grow EJ, Papas BN, Zhang Y, Kenan AC, Padilla-Banks E, Cairns BR, Williams CJ. Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation. Developmental Cell. PMID 32442396 DOI: 10.1016/j.devcel.2020.04.018  0.56
2020 Guo J, Nie X, Giebler M, Mlcochova H, Wang Y, Grow EJ, Kim R, Tharmalingam M, Matilionyte G, Lindskog C, Carrell DT, Mitchell RT, Goriely A, Hotaling JM, ... Cairns BR, et al. The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty. Cell Stem Cell. PMID 31928944 DOI: 10.1016/j.stem.2019.12.005  0.4
2019 Ye Y, Wu H, Chen K, Clapier CR, Verma N, Zhang W, Deng H, Cairns BR, Gao N, Chen Z. Structure of the RSC complex bound to the nucleosome. Science (New York, N.Y.). PMID 31672915 DOI: 10.1126/science.aay0033  0.56
2019 Cakiroglu A, Clapier CR, Ehrensberger AH, Darbo E, Cairns BR, Luscombe NM, Svejstrup J. Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2A.Z-containing nucleosomes. Genome Research. PMID 31097474 DOI: 10.1101/gr.243139.118  0.56
2019 Guo J, Cairns BR. Isolation and Enrichment of Spermatogonial Stem Cells From Human Testis Tissues. Current Protocols in Stem Cell Biology. e77. PMID 30609304 DOI: 10.1002/cpsc.77  0.36
2018 Jenkins TG, Aston KI, Cairns B, Smith A, Carrell DT. Paternal germ line aging: DNA methylation age prediction from human sperm. Bmc Genomics. 19: 763. PMID 30348084 DOI: 10.1186/s12864-018-5153-4  0.32
2018 Guo J, Grow EJ, Mlcochova H, Maher GJ, Lindskog C, Nie X, Guo Y, Takei Y, Yun J, Cai L, Kim R, Carrell DT, Goriely A, Hotaling JM, Cairns BR. The adult human testis transcriptional cell atlas. Cell Research. PMID 30315278 DOI: 10.1038/s41422-018-0099-2  0.4
2018 Gupta S, Albertson DJ, Parnell TJ, Butterfield A, Weston A, Pappas LM, Dalley B, O'Shea JM, Lowrance WT, Cairns BR, Schiffman JD, Sharma S. Histone deacetylase inhibition has targeted clinical benefit in ARID1A mutated advanced urothelial carcinoma. Molecular Cancer Therapeutics. PMID 30301863 DOI: 10.1158/1535-7163.MCT-17-0957  0.48
2018 Murphy PJ, Wu SF, James CR, Wike CL, Cairns BR. Placeholder Nucleosomes Underlie Germline-to-Embryo DNA Methylation Reprogramming. Cell. PMID 29456083 DOI: 10.1016/j.cell.2018.01.022  0.92
2017 Guo J, Grow EJ, Yi C, Mlcochova H, Maher GJ, Lindskog C, Murphy PJ, Wike CL, Carrell DT, Goriely A, Hotaling JM, Cairns BR. Chromatin and Single-Cell RNA-Seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development. Cell Stem Cell. 21: 533-546.e6. PMID 28985528 DOI: 10.1016/j.stem.2017.09.003  0.4
2017 Clapier CR, Iwasa J, Cairns BR, Peterson CL. Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes. Nature Reviews. Molecular Cell Biology. PMID 28512350 DOI: 10.1038/nrm.2017.26  0.56
2017 Hendrickson PG, Doráis JA, Grow EJ, Whiddon JL, Lim JW, Wike CL, Weaver BD, Pflueger C, Emery BR, Wilcox AL, Nix DA, Peterson CM, Tapscott SJ, Carrell DT, Cairns BR. Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons. Nature Genetics. PMID 28459457 DOI: 10.1038/ng.3844  0.48
2016 Ramakrishnan S, Pokhrel S, Palani S, Pflueger C, Parnell TJ, Cairns BR, Bhaskara S, Chandrasekharan MB. Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription. Nature Communications. 7: 11949. PMID 27325136 DOI: 10.1038/ncomms11949  1
2016 Clapier CR, Kasten MM, Parnell TJ, Viswanathan R, Szerlong H, Sirinakis G, Zhang Y, Cairns BR. Regulation of DNA Translocation Efficiency within the Chromatin Remodeler RSC/Sth1 Potentiates Nucleosome Sliding and Ejection. Molecular Cell. 62: 453-461. PMID 27153540 DOI: 10.1016/j.molcel.2016.03.032  1
2016 Hendrickson PG, Cairns BR. Tet proteins enhance the developmental hourglass. Nature Genetics. 48: 345-7. PMID 27023773 DOI: 10.1038/ng.3533  1
2015 Varshney D, Vavrova-Anderson J, Oler AJ, Cairns BR, White RJ. Selective repression of SINE transcription by RNA polymerase III. Mobile Genetic Elements. 5: 86-91. PMID 26942044 DOI: 10.1080/2159256X.2015.1096997  0.48
2015 Hammoud SS, Low DH, Yi C, Lee CL, Oatley JM, Payne CJ, Carrell DT, Guccione E, Cairns BR. Transcription and imprinting dynamics in developing postnatal male germline stem cells. Genes & Development. 29: 2312-24. PMID 26545815 DOI: 10.1101/gad.261925.115  0.48
2015 Huang F, Ramakrishnan S, Pokhrel S, Pflueger C, Parnell TJ, Kasten MM, Currie SL, Bhachech N, Horikoshi M, Graves BJ, Cairns BR, Bhaskara S, Chandrasekharan MB. Interaction of the Jhd2 H3K4 demethylase with chromatin is controlled by histone H2A surfaces and restricted by H2B ubiquitination. The Journal of Biological Chemistry. PMID 26451043 DOI: 10.1074/jbc.M115.693085  1
2015 Aston KI, Uren PJ, Jenkins TG, Horsager A, Cairns BR, Smith AD, Carrell DT. Aberrant sperm DNA methylation predicts male fertility status and embryo quality. Fertility and Sterility. PMID 26361204 DOI: 10.1016/j.fertnstert.2015.08.019  1
2015 Khoddami V, Yerra A, Cairns BR. Experimental Approaches for Target Profiling of RNA Cytosine Methyltransferases. Methods in Enzymology. 560: 273-96. PMID 26253975 DOI: 10.1016/bs.mie.2015.03.008  1
2015 Parnell TJ, Schlichter A, Wilson BG, Cairns BR. The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism. Elife. 4: e06073. PMID 25821983 DOI: 10.7554/eLife.06073  1
2015 Varshney D, Vavrova-Anderson J, Oler AJ, Cowling VH, Cairns BR, White RJ. SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation. Nature Communications. 6: 6569. PMID 25798578 DOI: 10.1038/ncomms7569  1
2015 Hammoud SS, Low DHP, Yi C, Lee CL, Oatley JM, Payne CJ, Carrell DT, Guccione E, Cairns BR. Transcription and imprinting dynamics in developing postnatal male germline stem cells Genes and Development. 29: 2312-2324. DOI: 10.1101/gad.261925  1
2015 Johnson DP, Spitz GS, Tharkar S, Quayle SN, Shearstone JR, Jones S, McDowell ME, Wellman H, Tyler JK, Cairns BR, Chandrasekharan MB, Bhaskara S. HDAC1,2 inhibition impairs EZH2- and BBAP- mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma Oncotarget. 6: 4863-4887.  1
2014 Jenkins TG, Aston KI, Pflueger C, Cairns BR, Carrell DT. Age-associated sperm DNA methylation alterations: possible implications in offspring disease susceptibility. Plos Genetics. 10: e1004458. PMID 25010591 DOI: 10.1371/journal.pgen.1004458  1
2014 Hammoud SS, Low DH, Yi C, Carrell DT, Guccione E, Cairns BR. Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis. Cell Stem Cell. 15: 239-53. PMID 24835570 DOI: 10.1016/j.stem.2014.04.006  1
2014 Alla RK, Cairns BR. RNA polymerase III transcriptomes in human embryonic stem cells and induced pluripotent stem cells, and relationships with pluripotency transcription factors. Plos One. 9: e85648. PMID 24465633 DOI: 10.1371/journal.pone.0085648  1
2014 Khoddami V, Cairns BR. Transcriptome-wide target profiling of RNA cytosine methyltransferases using the mechanism-based enrichment procedure Aza-IP. Nature Protocols. 9: 337-61. PMID 24434802 DOI: 10.1038/nprot.2014.014  1
2013 Hong C, Clement NL, Clement S, Hammoud SS, Carrell DT, Cairns BR, Snell Q, Clement MJ, Johnson WE. Probabilistic alignment leads to improved accuracy and read coverage for bisulfite sequencing data. Bmc Bioinformatics. 14: 337. PMID 24261665 DOI: 10.1186/1471-2105-14-337  1
2013 Nelson AC, Cauceglia JW, Merkley SD, Youngson NA, Oler AJ, Nelson RJ, Cairns BR, Whitelaw E, Potts WK. Reintroducing domesticated wild mice to sociality induces adaptive transgenerational effects on MUP expression. Proceedings of the National Academy of Sciences of the United States of America. 110: 19848-53. PMID 24248373 DOI: 10.1073/pnas.1310427110  1
2013 Bhaskara S, Jacques V, Rusche JR, Olson EN, Cairns BR, Chandrasekharan MB. Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression. Epigenetics & Chromatin. 6: 27. PMID 23947532 DOI: 10.1186/1756-8935-6-27  1
2013 Jenkins TG, Aston KI, Cairns BR, Carrell DT. Paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels. Fertility and Sterility. 100: 945-51. PMID 23809503 DOI: 10.1016/j.fertnstert.2013.05.039  1
2013 Potok ME, Nix DA, Parnell TJ, Cairns BR. Reprogramming the maternal zebrafish genome after fertilization to match the paternal methylation pattern. Cell. 153: 759-72. PMID 23663776 DOI: 10.1016/j.cell.2013.04.030  1
2013 Khoddami V, Cairns BR. Identification of direct targets and modified bases of RNA cytosine methyltransferases. Nature Biotechnology. 31: 458-64. PMID 23604283 DOI: 10.1038/nbt.2566  1
2013 Hammoud SS, Cairns BR, Jones DA. Epigenetic regulation of colon cancer and intestinal stem cells. Current Opinion in Cell Biology. 25: 177-83. PMID 23402869 DOI: 10.1016/  1
2013 Schubert HL, Wittmeyer J, Kasten MM, Hinata K, Rawling DC, Héroux A, Cairns BR, Hill CP. Structure of an actin-related subcomplex of the SWI/SNF chromatin remodeler. Proceedings of the National Academy of Sciences of the United States of America. 110: 3345-50. PMID 23401505 DOI: 10.1073/pnas.1215379110  1
2013 Ehrensberger KM, Mason C, Corkins ME, Anderson C, Dutrow N, Cairns BR, Dalley B, Milash B, Bird AJ. Zinc-dependent regulation of the Adh1 antisense transcript in fission yeast. The Journal of Biological Chemistry. 288: 759-69. PMID 23223230 DOI: 10.1074/jbc.M112.406165  1
2013 Hammoud SS, Cairns BR, Carrell DT. Analysis of gene-specific and genome-wide sperm DNA methylation. Methods in Molecular Biology (Clifton, N.J.). 927: 451-8. PMID 22992936 DOI: 10.1007/978-1-62703-038-0_39  1
2012 Clapier CR, Cairns BR. Regulation of ISWI involves inhibitory modules antagonized by nucleosomal epitopes. Nature. 492: 280-4. PMID 23143334 DOI: 10.1038/nature11625  1
2012 Oler AJ, Traina-Dorge S, Derbes RS, Canella D, Cairns BR, Roy-Engel AM. Alu expression in human cell lines and their retrotranspositional potential. Mobile Dna. 3: 11. PMID 22716230 DOI: 10.1186/1759-8753-3-11  1
2012 Luo W, Milash B, Dalley B, Smith R, Zhou H, Dutrow N, Cairns BR, Lessnick SL. Antibody detection of translocations in Ewing sarcoma. Embo Molecular Medicine. 4: 453-61. PMID 22419563 DOI: 10.1002/emmm.201200225  1
2012 Oler AJ, Cairns BR. PP4 dephosphorylates Maf1 to couple multiple stress conditions to RNA polymerase III repression. The Embo Journal. 31: 1440-52. PMID 22333918 DOI: 10.1038/emboj.2011.501  1
2012 Swierczek SI, Piterkova L, Jelinek J, Agarwal N, Hammoud S, Wilson A, Hickman K, Parker CJ, Cairns BR, Cairns B, Prchal JT. Methylation of AR locus does not always reflect X chromosome inactivation state. Blood. 119: e100-9. PMID 22286197 DOI: 10.1182/blood-2011-11-390351  1
2011 Wu SF, Zhang H, Hammoud SS, Potok M, Nix DA, Jones DA, Cairns BR. DNA methylation profiling in zebrafish. Methods in Cell Biology. 104: 327-39. PMID 21924171 DOI: 10.1016/B978-0-12-374814-0.00018-5  1
2011 Malik SS, Rich E, Viswanathan R, Cairns BR, Fischer CJ. Allosteric interactions of DNA and nucleotides with S. cerevisiae RSC. Biochemistry. 50: 7881-90. PMID 21834590 DOI: 10.1021/bi200837b  1
2011 Hammoud SS, Nix DA, Hammoud AO, Gibson M, Cairns BR, Carrell DT. Genome-wide analysis identifies changes in histone retention and epigenetic modifications at developmental and imprinted gene loci in the sperm of infertile men. Human Reproduction (Oxford, England). 26: 2558-69. PMID 21685136 DOI: 10.1093/humrep/der192  1
2011 Sirinakis G, Clapier CR, Gao Y, Viswanathan R, Cairns BR, Zhang Y. The RSC chromatin remodelling ATPase translocates DNA with high force and small step size. The Embo Journal. 30: 2364-72. PMID 21552204 DOI: 10.1038/emboj.2011.141  1
2011 Wu SF, Zhang H, Cairns BR. Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm. Genome Research. 21: 578-89. PMID 21383318 DOI: 10.1101/gr.113167.110  1
2011 Kasten MM, Clapier CR, Cairns BR. SnapShot: Chromatin remodeling: SWI/SNF. Cell. 144: 310.e1. PMID 21241897 DOI: 10.1016/j.cell.2011.01.007  1
2010 Rai K, Sarkar S, Broadbent TJ, Voas M, Grossmann KF, Nadauld LD, Dehghanizadeh S, Hagos FT, Li Y, Toth RK, Chidester S, Bahr TM, Johnson WE, Sklow B, Burt R, ... Cairns BR, et al. DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC. Cell. 142: 930-42. PMID 20850014 DOI: 10.1016/j.cell.2010.08.030  1
2010 Oler AJ, Alla RK, Roberts DN, Wong A, Hollenhorst PC, Chandler KJ, Cassiday PA, Nelson CA, Hagedorn CH, Graves BJ, Cairns BR. Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors. Nature Structural & Molecular Biology. 17: 620-8. PMID 20418882 DOI: 10.1038/nsmb.1801  1
2010 Rai K, Jafri IF, Chidester S, James SR, Karpf AR, Cairns BR, Jones DA. Dnmt3 and G9a cooperate for tissue-specific development in zebrafish. The Journal of Biological Chemistry. 285: 4110-21. PMID 19946145 DOI: 10.1074/jbc.M109.073676  1
2010 Hammoud SS, Purwar J, Pflueger C, Cairns BR, Carrell DT. Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility. Fertility and Sterility. 94: 1728-33. PMID 19880108 DOI: 10.1016/j.fertnstert.2009.09.010  1
2010 Clement NL, Snell Q, Clement MJ, Hollenhorst PC, Purwar J, Graves BJ, Cairns BR, Johnson WE. The GNUMAP algorithm: unbiased probabilistic mapping of oligonucleotides from next-generation sequencing. Bioinformatics (Oxford, England). 26: 38-45. PMID 19861355 DOI: 10.1093/bioinformatics/btp614  1
2009 Cairns BR. The logic of chromatin architecture and remodelling at promoters. Nature. 461: 193-8. PMID 19741699 DOI: 10.1038/nature08450  1
2009 Hammoud SS, Nix DA, Zhang H, Purwar J, Carrell DT, Cairns BR. Distinctive chromatin in human sperm packages genes for embryo development. Nature. 460: 473-8. PMID 19525931 DOI: 10.1038/nature08162  1
2009 Clapier CR, Cairns BR. The biology of chromatin remodeling complexes. Annual Review of Biochemistry. 78: 273-304. PMID 19355820 DOI: 10.1146/annurev.biochem.77.062706.153223  1
2008 Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell. 135: 1201-12. PMID 19109892 DOI: 10.1016/j.cell.2008.11.042  1
2008 Dutrow N, Nix DA, Holt D, Milash B, Dalley B, Westbroek E, Parnell TJ, Cairns BR. Dynamic transcriptome of Schizosaccharomyces pombe shown by RNA-DNA hybrid mapping. Nature Genetics. 40: 977-86. PMID 18641648 DOI: 10.1038/ng.196  1
2008 Szerlong H, Hinata K, Viswanathan R, Erdjument-Bromage H, Tempst P, Cairns BR. The HSA domain binds nuclear actin-related proteins to regulate chromatin-remodeling ATPases. Nature Structural & Molecular Biology. 15: 469-76. PMID 18408732 DOI: 10.1038/nsmb.1403  1
2008 Parnell TJ, Huff JT, Cairns BR. RSC regulates nucleosome positioning at Pol II genes and density at Pol III genes. The Embo Journal. 27: 100-10. PMID 18059476 DOI: 10.1038/sj.emboj.7601946  1
2007 Cairns BR. Chromatin remodeling: insights and intrigue from single-molecule studies. Nature Structural & Molecular Biology. 14: 989-96. PMID 17984961 DOI: 10.1038/nsmb1333  1
2007 Fischer CJ, Saha A, Cairns BR. Kinetic model for the ATP-dependent translocation of Saccharomyces cerevisiae RSC along double-stranded DNA. Biochemistry. 46: 12416-26. PMID 17918861 DOI: 10.1021/bi700930n  1
2007 VanDemark AP, Kasten MM, Ferris E, Heroux A, Hill CP, Cairns BR. Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. Molecular Cell. 27: 817-28. PMID 17803945 DOI: 10.1016/j.molcel.2007.08.018  1
2007 Gordon M, Holt DG, Panigrahi A, Wilhelm BT, Erdjument-Bromage H, Tempst P, Bähler J, Cairns BR. Genome-wide dynamics of SAPHIRE, an essential complex for gene activation and chromatin boundaries. Molecular and Cellular Biology. 27: 4058-69. PMID 17371846 DOI: 10.1128/MCB.02044-06  1
2007 Leschziner AE, Saha A, Wittmeyer J, Zhang Y, Bustamante C, Cairns BR, Nogales E. Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method. Proceedings of the National Academy of Sciences of the United States of America. 104: 4913-8. PMID 17360331 DOI: 10.1073/pnas.0700706104  1
2007 Rai K, Chidester S, Zavala CV, Manos EJ, James SR, Karpf AR, Jones DA, Cairns BR. Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish. Genes & Development. 21: 261-6. PMID 17289917 DOI: 10.1101/gad.1472907  1
2006 Zhang Y, Smith CL, Saha A, Grill SW, Mihardja S, Smith SB, Cairns BR, Peterson CL, Bustamante C. DNA translocation and loop formation mechanism of chromatin remodeling by SWI/SNF and RSC. Molecular Cell. 24: 559-68. PMID 17188033 DOI: 10.1016/j.molcel.2006.10.025  1
2006 Rai K, Nadauld LD, Chidester S, Manos EJ, James SR, Karpf AR, Cairns BR, Jones DA. Zebra fish Dnmt1 and Suv39h1 regulate organ-specific terminal differentiation during development. Molecular and Cellular Biology. 26: 7077-85. PMID 16980612 DOI: 10.1128/MCB.00312-06  1
2006 Saha A, Wittmeyer J, Cairns BR. Mechanisms for nucleosome movement by ATP-dependent chromatin remodeling complexes. Results and Problems in Cell Differentiation. 41: 127-48. PMID 16909894 DOI: 10.1007/400_005  1
2006 Soutourina J, Bordas-Le Floch V, Gendrel G, Flores A, Ducrot C, Dumay-Odelot H, Soularue P, Navarro F, Cairns BR, Lefebvre O, Werner M. Rsc4 connects the chromatin remodeler RSC to RNA polymerases. Molecular and Cellular Biology. 26: 4920-33. PMID 16782880 DOI: 10.1128/MCB.00415-06  1
2006 Roberts DN, Wilson B, Huff JT, Stewart AJ, Cairns BR. Dephosphorylation and genome-wide association of Maf1 with Pol III-transcribed genes during repression. Molecular Cell. 22: 633-44. PMID 16762836 DOI: 10.1016/j.molcel.2006.04.009  1
2006 Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D, Peña P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A, Cairns BR, et al. ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression. Nature. 442: 96-9. PMID 16728974 DOI: 10.1038/nature04835  1
2006 Saha A, Wittmeyer J, Cairns BR. Chromatin remodelling: the industrial revolution of DNA around histones. Nature Reviews. Molecular Cell Biology. 7: 437-47. PMID 16723979 DOI: 10.1038/nrm1945  1
2006 Da G, Lenkart J, Zhao K, Shiekhattar R, Cairns BR, Marmorstein R. Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes. Proceedings of the National Academy of Sciences of the United States of America. 103: 2057-62. PMID 16461455 DOI: 10.1073/pnas.0510949103  1
2006 Wilson B, Erdjument-Bromage H, Tempst P, Cairns BR. The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles. Genetics. 172: 795-809. PMID 16204215 DOI: 10.1534/genetics.105.047589  1
2005 Zhang H, Roberts DN, Cairns BR. Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss. Cell. 123: 219-31. PMID 16239141 DOI: 10.1016/j.cell.2005.08.036  1
2005 Saha A, Wittmeyer J, Cairns BR. Chromatin remodeling through directional DNA translocation from an internal nucleosomal site. Nature Structural & Molecular Biology. 12: 747-55. PMID 16086025 DOI: 10.1038/nsmb973  1
2005 Chai B, Huang J, Cairns BR, Laurent BC. Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair. Genes & Development. 19: 1656-61. PMID 16024655 DOI: 10.1101/gad.1273105  1
2005 Cairns BR. Chromatin remodeling complexes: strength in diversity, precision through specialization. Current Opinion in Genetics & Development. 15: 185-90. PMID 15797201 DOI: 10.1016/j.gde.2005.01.003  1
2005 Schlichter A, Cairns BR. Histone trimethylation by Set1 is coordinated by the RRM, autoinhibitory, and catalytic domains. The Embo Journal. 24: 1222-31. PMID 15775977 DOI: 10.1038/sj.emboj.7600607  1
2004 Cairns BR. Around the world of DNA damage INO80 days. Cell. 119: 733-5. PMID 15607967 DOI: 10.1016/j.cell.2004.12.005  1
2004 Zhang H, Richardson DO, Roberts DN, Utley R, Erdjument-Bromage H, Tempst P, Côté J, Cairns BR. The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres. Molecular and Cellular Biology. 24: 9424-36. PMID 15485911 DOI: 10.1128/MCB.24.21.9424-9436.2004  1
2004 Kasten M, Szerlong H, Erdjument-Bromage H, Tempst P, Werner M, Cairns BR. Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14. The Embo Journal. 23: 1348-59. PMID 15014446 DOI: 10.1038/sj.emboj.7600143  1
2003 Roberts DN, Stewart AJ, Huff JT, Cairns BR. The RNA polymerase III transcriptome revealed by genome-wide localization and activity-occupancy relationships. Proceedings of the National Academy of Sciences of the United States of America. 100: 14695-700. PMID 14634212 DOI: 10.1073/pnas.2435566100  1
2003 Szerlong H, Saha A, Cairns BR. The nuclear actin-related proteins Arp7 and Arp9: a dimeric module that cooperates with architectural proteins for chromatin remodeling. The Embo Journal. 22: 3175-87. PMID 12805231 DOI: 10.1093/emboj/cdg296  1
2003 Kristjuhan A, Wittschieben BO, Walker J, Roberts D, Cairns BR, Svejstrup JQ. Spreading of Sir3 protein in cells with severe histone H3 hypoacetylation. Proceedings of the National Academy of Sciences of the United States of America. 100: 7551-6. PMID 12796514 DOI: 10.1073/pnas.1332299100  1
2002 Kristjuhan A, Walker J, Suka N, Grunstein M, Roberts D, Cairns BR, Svejstrup JQ. Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region. Molecular Cell. 10: 925-33. PMID 12419235 DOI: 10.1016/S1097-2765(02)00647-0  1
2002 Romeo MJ, Angus-Hill ML, Sobering AK, Kamada Y, Cairns BR, Levin DE. HTL1 encodes a novel factor that interacts with the RSC chromatin remodeling complex in Saccharomyces cerevisiae. Molecular and Cellular Biology. 22: 8165-74. PMID 12417720 DOI: 10.1128/MCB.22.23.8165-8174.2002  1
2002 Saha A, Wittmeyer J, Cairns BR. Chromatin remodeling by RSC involves ATP-dependent DNA translocation. Genes & Development. 16: 2120-34. PMID 12183366 DOI: 10.1101/gad.995002  1
2002 Damelin M, Simon I, Moy TI, Wilson B, Komili S, Tempst P, Roth FP, Young RA, Cairns BR, Silver PA. The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress. Molecular Cell. 9: 563-73. PMID 11931764 DOI: 10.1016/S1097-2765(02)00475-6  1
2001 Cairns BR. Emerging roles for chromatin remodeling in cancer biology Trends in Cell Biology. 11. PMID 11684437 DOI: 10.1016/S0962-8924(01)02125-0  1
2001 Angus-Hill ML, Schlichter A, Roberts D, Erdjument-Bromage H, Tempst P, Cairns BR. A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control Molecular Cell. 7: 741-751. PMID 11336698 DOI: 10.1016/S1097-2765(01)00219-2  1
2001 Sengupta SM, VanKanegan M, Persinger J, Logie C, Cairns BR, Peterson CL, Bartholomew B. The interactions of yeast SWI/SNF and RSC with the nucleosome before and after chromatin remodeling. The Journal of Biological Chemistry. 276: 12636-44. PMID 11304548  1
2001 Cairns BR. Silent chromatin - Holding transcription hostage? Trends in Biochemical Sciences. 26: 411-412.  1
1999 Cairns BR, Schlichter A, Erdjument-Bromage H, Tempst P, Kornberg RD, Winston F. Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains. Molecular Cell. 4: 715-23. PMID 10619019 DOI: 10.1016/S1097-2765(00)80382-2  1
1999 Neely KE, Hassan AH, Wallberg AE, Steger DJ, Cairns BR, Wright AP, Workman JL. Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays. Molecular Cell. 4: 649-55. PMID 10549297 DOI: 10.1016/S1097-2765(00)80216-6  1
1999 Whitehouse I, Flaus A, Cairns BR, White MF, Workman JL, Owen-Hughes T. Nucleosome mobilization catalysed by the yeast SWI/SNF complex. Nature. 400: 784-7. PMID 10466730 DOI: 10.1038/23506  1
1998 Cairns BR, Erdjument-Bromage H, Tempst P, Winston F, Kornberg RD. Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF. Molecular Cell. 2: 639-51. PMID 9844636  1
1998 Lorch Y, Cairns BR, Zhang M, Kornberg RD. Activated RSC-nucleosome complex and persistently altered form of the nucleosome. Cell. 94: 29-34. PMID 9674424 DOI: 10.1016/S0092-8674(00)81218-0  1
1998 Cairns BR. Chromatin remodeling machines: Similar motors, ulterior motives Trends in Biochemical Sciences. 23: 20-24. PMID 9478131 DOI: 10.1016/S0968-0004(97)01160-2  1
1997 Cao Y, Cairns BR, Kornberg RD, Laurent BC. Sfh1p, a component of a novel chromatin-remodeling complex, is required for cell cycle progression. Molecular and Cellular Biology. 17: 3323-34. PMID 9154831  1
1996 Cairns BR, Lorch Y, Li Y, Zhang M, Lacomis L, Erdjument-Bromage H, Tempst P, Du J, Laurent B, Kornberg RD. RSC, an essential, abundant chromatin-remodeling complex. Cell. 87: 1249-60. PMID 8980231 DOI: 10.1016/S0092-8674(00)81820-6  1
1996 Miller ME, Cairns BR, Levinson RS, Yamamoto KR, Engel DA, Smith MM. Adenovirus E1A specifically blocks SWI/SNF-dependent transcriptional activation. Molecular and Cellular Biology. 16: 5737-43. PMID 8816487  1
1996 Cairns BR, Levinson RS, Yamamoto KR, Kornberg RD. Essential role of Swp73p in the function of yeast Swi/Snf complex. Genes & Development. 10: 2131-44. PMID 8804308  1
1996 Wang W, Xue Y, Zhou S, Kuo A, Cairns BR, Crabtree GR. Diversity and specialization of mammalian SWI/SNF complexes. Genes & Development. 10: 2117-30. PMID 8804307  1
1996 Bardwell L, Cook JG, Chang EC, Cairns BR, Thorner J. Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7. Molecular and Cellular Biology. 16: 3637-50. PMID 8668180  1
1996 Cairns BR, Henry NL, Kornberg RD. TFG/TAF30/ANC1, a component of the yeast SWI/SNF complex that is similar to the leukemogenic proteins ENL and AF-9. Molecular and Cellular Biology. 16: 3308-16. PMID 8668146  1
1995 Treich I, Cairns BR, De los Santos T, Brewster E, Carlson M. SNF11, a new component of the yeast SNF-SWI complex that interacts with a conserved region of SNF2 Molecular and Cellular Biology. 15: 4240-4248. PMID 7623818 DOI: 10.1128/MCB.15.8.4240  1
1994 Cairns BR, Kim YJ, Sayre MH, Laurent BC, Kornberg RD. A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast Proceedings of the National Academy of Sciences of the United States of America. 91: 1950-1954. PMID 8127913  1
1992 Cairns BR, Ramer SW, Kornberg RD. Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase Genes and Development. 6: 1305-1318. PMID 1628833  1
1991 Genske JE, Cairns BR, Stack SP, Landfear SM. Structure and Regulation of Histone H2B mRNAs from Leishmania enriettii Molecular and Cellular Biology. 11: 240-249. PMID 1986223  1
1990 Stein DA, Cairns BR, Landfear SM. Developmentally regulated transporter in Leishmania is encoded by a family of clustered genes Nucleic Acids Research. 18: 1549-1557. PMID 2326193 DOI: 10.1093/nar/18.6.1549  1
1989 Cairns BR, Collard MW, Landfear SM. Developmentally regulated gene from Leishmania encodes a putative membrane transport protein Proceedings of the National Academy of Sciences of the United States of America. 86: 7682-7686. PMID 2813352  1
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