Anjana Rao - Publications

Harvard University, Cambridge, MA, United States 
Molecular Biology, Biochemistry

197 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Reilly BM, Luger T, Park S, Lio CJ, Gonzalez-Avalos E, Wheeler EC, Lee M, Williamson L, Tanaka T, Diep D, Zhang K, Huang Y, Rao A, Bejar R. 5-Azacytidine Transiently Restores Dysregulated Erythroid Differentiation Gene Expression in TET2-Deficient Erythroleukemia Cells. Molecular Cancer Research : McR. PMID 33172974 DOI: 10.1158/1541-7786.MCR-20-0453  1
2020 Yue X, Rao A. TET-family dioxygenases and the TET activator Vitamin C in immune responses and cancer. Blood. PMID 32730592 DOI: 10.1182/blood.2019004158  0.48
2020 Kim Y, Sundrud MS, Zhou C, Edenius M, Zocco D, Powers K, Zhang M, Mazitschek R, Rao A, Yeo CY, Noss EH, Brenner MB, Whitman M, Keller TL. Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32253314 DOI: 10.1073/pnas.1913788117  0.52
2020 Shukla V, Halabelian L, Balagere S, Samaniego-Castruita D, Feldman DE, Arrowsmith CH, Rao A, Aravind L. HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells. Molecular Cell. 77: 1154. PMID 32142687 DOI: 10.1016/j.molcel.2020.02.008  0.4
2020 Lio CJ, Yue X, Lopez-Moyado IF, Tahiliani M, Aravind L, Rao A. TET methylcytosine oxidases: new insights from a decade of research. Journal of Biosciences. 45. PMID 31965999  0.72
2019 Shukla V, Halabelian L, Balagere S, Samaniego-Castruita D, Feldman DE, Arrowsmith CH, Rao A, Aravind L. HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells. Molecular Cell. PMID 31806351 DOI: 10.1016/j.molcel.2019.10.031  0.4
2019 Blank CU, Haining WN, Held W, Hogan PG, Kallies A, Lugli E, Lynn RC, Philip M, Rao A, Restifo NP, Schietinger A, Schumacher TN, Schwartzberg PL, Sharpe AH, Speiser DE, et al. Defining 'T cell exhaustion'. Nature Reviews. Immunology. PMID 31570879 DOI: 10.1038/s41577-019-0221-9  0.96
2019 Lio CJ, Yuita H, Rao A. Dysregulation of the TET family of epigenetic regulators in hematopoietic malignancies. Blood. PMID 31467060 DOI: 10.1182/blood.2019791475  0.6
2019 Aravind L, Balasubramanian S, Rao A. Unusual Activity of a TET/JBP Family Enzyme. Biochemistry. PMID 31436949 DOI: 10.1021/acs.biochem.9b00609  0.4
2019 López-Moyado IF, Tsagaratou A, Yuita H, Seo H, Delatte B, Heinz S, Benner C, Rao A. Paradoxical association of TET loss of function with genome-wide DNA hypomethylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31371502 DOI: 10.1073/pnas.1903059116  0.64
2019 Halabelian L, Ravichandran M, Li Y, Zeng H, Rao A, Aravind L, Arrowsmith CH. Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. Nature Structural & Molecular Biology. PMID 31235913 DOI: 10.1038/s41594-019-0246-6  0.4
2019 Seo H, Chen J, González-Avalos E, Samaniego-Castruita D, Das A, Wang YH, López-Moyado IF, Georges RO, Zhang W, Onodera A, Wu CJ, Lu LF, Hogan PG, Bhandoola A, Rao A. TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8 T cell exhaustion. Proceedings of the National Academy of Sciences of the United States of America. PMID 31152140 DOI: 10.1073/pnas.1905675116  0.96
2019 Yue X, Lio CJ, Samaniego-Castruita D, Li X, Rao A. Loss of TET2 and TET3 in regulatory T cells unleashes effector function. Nature Communications. 10: 2011. PMID 31043609 DOI: 10.1038/s41467-019-09541-y  0.6
2019 Lio CJ, Shukla V, Samaniego-Castruita D, González-Avalos E, Chakraborty A, Yue X, Schatz DG, Ay F, Rao A. TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the superenhancer. Science Immunology. 4. PMID 31028100 DOI: 10.1126/sciimmunol.aau7523  0.6
2019 Mognol GP, González-Avalos E, Ghosh S, Spreafico R, Gudlur A, Rao A, Damoiseaux R, Hogan PG. Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31019078 DOI: 10.1073/pnas.1820604116  0.96
2019 Chen J, López-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A. NR4A transcription factors limit CAR T cell function in solid tumours. Nature. PMID 30814732 DOI: 10.1038/s41586-019-0985-x  0.6
2019 Lio CJ, Rao A. TET Enzymes and 5hmC in Adaptive and Innate Immune Systems. Frontiers in Immunology. 10: 210. PMID 30809228 DOI: 10.3389/fimmu.2019.00210  0.6
2018 Shepherd MS, Li J, Wilson NK, Oedekoven CA, Li J, Belmonte M, Fink J, Prick JCM, Pask DC, Hamilton TL, Löffler D, Rao A, Schroeder T, Göttgens B, Green AR, et al. Single cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal. Blood. PMID 29991556 DOI: 10.1182/blood-2017-12-821066  0.48
2018 Tuttle KD, Krovi SH, Zhang J, Bedel R, Harmacek L, Peterson LK, Dragone LL, Lefferts A, Halluszczak C, Riemondy K, Hesselberth JR, Rao A, O'Connor BP, Marrack P, Scott-Browne J, et al. TCR signal strength controls thymic differentiation of iNKT cell subsets. Nature Communications. 9: 2650. PMID 29985393 DOI: 10.1038/s41467-018-05026-6  0.6
2017 Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW. Erratum: The microRNA miR-31 inhibits CD8(+) T cell function in chronic viral infection. Nature Immunology. 18: 1173. PMID 28926530 DOI: 10.1038/ni1017-1173d  0.48
2017 Scott-Browne JP, Lio CJ, Rao A. TET proteins in natural and induced differentiation. Current Opinion in Genetics & Development. 46: 202-208. PMID 28888139 DOI: 10.1016/j.gde.2017.07.011  0.6
2017 Montagner S, Leoni C, Emming S, Della Chiara G, Balestrieri C, Barozzi I, Piccolo V, Togher S, Ko M, Rao A, Natoli G, Monticelli S. TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities. Cell Reports. 20: 1744. PMID 28813683 DOI: 10.1016/j.celrep.2017.08.011  0.48
2017 Zang S, Li J, Yang H, Zeng H, Han W, Zhang J, Lee M, Moczygemba M, Isgandarova S, Yang Y, Zhou Y, Rao A, You MJ, Sun D, Huang Y. Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis. The Journal of Clinical Investigation. PMID 28691928 DOI: 10.1172/JCI92026  1
2017 Pereira RM, Hogan PG, Rao A, Martinez GJ. Transcriptional and epigenetic regulation of T cell hyporesponsiveness. Journal of Leukocyte Biology. PMID 28606939 DOI: 10.1189/jlb.2RI0317-097R  0.96
2017 Moffett HF, Cartwright ANR, Kim HJ, Godec J, Pyrdol J, Äijö T, Martinez GJ, Rao A, Lu J, Golub TR, Cantor H, Sharpe AH, Novina CD, Wucherpfennig KW. The microRNA miR-31 inhibits CD8(+) T cell function in chronic viral infection. Nature Immunology. PMID 28530712 DOI: 10.1038/ni.3755  0.48
2017 An J, Rao A, Ko M. TET family dioxygenases and DNA demethylation in stem cells and cancers. Experimental & Molecular Medicine. 49: e323. PMID 28450733 DOI: 10.1038/emm.2017.5  0.44
2017 Tsagaratou A, Lio CJ, Yue X, Rao A. TET Methylcytosine Oxidases in T Cell and B Cell Development and Function. Frontiers in Immunology. 8: 220. PMID 28408905 DOI: 10.3389/fimmu.2017.00220  0.64
2017 Mognol GP, Spreafico R, Wong V, Scott-Browne JP, Togher S, Hoffmann A, Hogan PG, Rao A, Trifari S. Exhaustion-associated regulatory regions in CD8(+) tumor-infiltrating T cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28283662 DOI: 10.1073/pnas.1620498114  0.96
2017 Tsagaratou A, González-Avalos E, Rautio S, Scott-Browne JP, Togher S, Pastor WA, Rothenberg EV, Chavez L, Lähdesmäki H, Rao A. TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells. Nature Immunology. 18: 45-53. PMID 27869820 DOI: 10.1038/ni.3630  0.88
2016 Scott-Browne JP, López-Moyado IF, Trifari S, Wong V, Chavez L, Rao A, Pereira RM. Dynamic Changes in Chromatin Accessibility Occur in CD8(+) T Cells Responding to Viral Infection. Immunity. PMID 27939672 DOI: 10.1016/j.immuni.2016.10.028  0.48
2016 Li X, Yue X, Pastor WA, Lin L, Georges R, Chavez L, Evans SM, Rao A. Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 27930333 DOI: 10.1073/pnas.1617802113  0.88
2016 Lio CJ, Zhang J, González-Avalos E, Hogan PG, Chang X, Rao A. Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility. Elife. 5. PMID 27869616 DOI: 10.7554/eLife.18290  0.96
2016 Spira A, Disis ML, Schiller JT, Vilar E, Rebbeck TR, Bejar R, Ideker T, Arts J, Yurgelun MB, Mesirov JP, Rao A, Garber J, Jaffee EM, Lippman SM. Leveraging premalignant biology for immune-based cancer prevention. Proceedings of the National Academy of Sciences of the United States of America. PMID 27638202 DOI: 10.1073/pnas.1608077113  0.56
2016 Äijö T, Yue X, Rao A, Lähdesmäki H. LuxGLM: a probabilistic covariate model for quantification of DNA methylation modifications with complex experimental designs. Bioinformatics (Oxford, England). 32: i511-i519. PMID 27587669 DOI: 10.1093/bioinformatics/btw468  0.48
2016 Zhang X, Su J, Jeong M, Ko M, Huang Y, Park HJ, Guzman A, Lei Y, Huang YH, Rao A, Li W, Goodell MA. DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells. Nature Genetics. PMID 27428748 DOI: 10.1038/ng.3610  0.56
2016 Montagner S, Leoni C, Emming S, Della Chiara G, Balestrieri C, Barozzi I, Piccolo V, Togher S, Ko M, Rao A, Natoli G, Monticelli S. TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities. Cell Reports. PMID 27160912 DOI: 10.1016/j.celrep.2016.04.044  0.48
2016 Äijö T, Huang Y, Mannerström H, Chavez L, Tsagaratou A, Rao A, Lähdesmäki H. A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways. Genome Biology. 17: 49. PMID 26975309 DOI: 10.1186/s13059-016-0911-6  1
2016 Yue X, Trifari S, Äijö T, Tsagaratou A, Pastor WA, Zepeda-Martínez JA, Lio CJ, Li X, Huang Y, Vijayanand P, Lähdesmäki H, Rao A. Control of Foxp3 stability through modulation of TET activity. The Journal of Experimental Medicine. PMID 26903244 DOI: 10.1084/jem.20151438  0.88
2016 Martinez GJ, Hu JK, Pereira RM, Crampton JS, Togher S, Bild N, Crotty S, Rao A. Cutting Edge: NFAT Transcription Factors Promote the Generation of Follicular Helper T Cells in Response to Acute Viral Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26851216 DOI: 10.4049/jimmunol.1501841  0.88
2015 Quintana A, Rajanikanth V, Farber-Katz S, Gudlur A, Zhang C, Jing J, Zhou Y, Rao A, Hogan PG. TMEM110 regulates the maintenance and remodeling of mammalian ER-plasma membrane junctions competent for STIM-ORAI signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644574 DOI: 10.1073/pnas.1521924112  0.88
2015 An J, González-Avalos E, Chawla A, Jeong M, López-Moyado IF, Li W, Goodell MA, Chavez L, Ko M, Rao A. Acute loss of TET function results in aggressive myeloid cancer in mice. Nature Communications. 6: 10071. PMID 26607761 DOI: 10.1038/ncomms10071  0.88
2015 Ko M, An J, Rao A. DNA methylation and hydroxymethylation in hematologic differentiation and transformation. Current Opinion in Cell Biology. 37: 91-101. PMID 26595486 DOI: 10.1016/  0.88
2015 Kang J, Lienhard M, Pastor WA, Chawla A, Novotny M, Tsagaratou A, Lasken RS, Thompson EC, Surani MA, Koralov SB, Kalantry S, Chavez L, Rao A. Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: E4236-45. PMID 26199412 DOI: 10.1073/pnas.1510510112  0.88
2015 Balasubramani A, Larjo A, Bassein JA, Chang X, Hastie RB, Togher SM, Lähdesmäki H, Rao A. Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex. Nature Communications. 6: 7307. PMID 26095772 DOI: 10.1038/ncomms8307  0.6
2015 Hogan PG, Rao A. Store-operated calcium entry: Mechanisms and modulation. Biochemical and Biophysical Research Communications. 460: 40-9. PMID 25998732 DOI: 10.1016/j.bbrc.2015.02.110  0.96
2015 Etchegaray JP, Chavez L, Huang Y, Ross KN, Choi J, Martinez-Pastor B, Walsh RM, Sommer CA, Lienhard M, Gladden A, Kugel S, Silberman DM, Ramaswamy S, Mostoslavsky G, Hochedlinger K, ... ... Rao A, et al. The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine. Nature Cell Biology. 17: 545-57. PMID 25915124 DOI: 10.1038/ncb3147  0.88
2015 Chang X, Li B, Rao A. RNA-binding protein hnRNPLL regulates mRNA splicing and stability during B-cell to plasma-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 112: E1888-97. PMID 25825742 DOI: 10.1073/pnas.1422490112  0.6
2015 Martinez GJ, Pereira RM, Äijö T, Kim EY, Marangoni F, Pipkin ME, Togher S, Heissmeyer V, Zhang YC, Crotty S, Lamperti ED, Ansel KM, Mempel TR, Lähdesmäki H, Hogan PG, ... Rao A, et al. The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells. Immunity. 42: 265-78. PMID 25680272 DOI: 10.1016/j.immuni.2015.01.006  0.88
2015 Gjini E, Mansour MR, Sander JD, Moritz N, Nguyen AT, Kesarsing M, Gans E, He S, Chen S, Ko M, Kuang YY, Yang S, Zhou Y, Rodig S, Zon LI, ... ... Rao A, et al. A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. Molecular and Cellular Biology. 35: 789-804. PMID 25512612 DOI: 10.1128/MCB.00971-14  0.56
2015 Ko M, An J, Pastor WA, Koralov SB, Rajewsky K, Rao A. TET proteins and 5-methylcytosine oxidation in hematological cancers. Immunological Reviews. 263: 6-21. PMID 25510268 DOI: 10.1111/imr.12239  0.88
2014 Chavez L, Huang Y, Luong K, Agarwal S, Iyer LM, Pastor WA, Hench VK, Frazier-Bowers SA, Korol E, Liu S, Tahiliani M, Wang Y, Clark TA, Korlach J, Pukkila PJ, ... ... Rao A, et al. Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea. Proceedings of the National Academy of Sciences of the United States of America. 111: E5149-58. PMID 25406324 DOI: 10.1073/pnas.1419513111  0.88
2014 Chen R, Bélanger S, Frederick MA, Li B, Johnston RJ, Xiao N, Liu YC, Sharma S, Peters B, Rao A, Crotty S, Pipkin ME. In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation. Immunity. 41: 325-38. PMID 25148027 DOI: 10.1016/j.immuni.2014.08.002  0.88
2014 Huang Y, Rao A. Connections between TET proteins and aberrant DNA modification in cancer. Trends in Genetics : Tig. 30: 464-74. PMID 25132561 DOI: 10.1016/j.tig.2014.07.005  1
2014 Pereira RM, Martinez GJ, Engel I, Cruz-Guilloty F, Barboza BA, Tsagaratou A, Lio CW, Berg LJ, Lee Y, Kronenberg M, Bandukwala HS, Rao A. Jarid2 is induced by TCR signalling and controls iNKT cell maturation. Nature Communications. 5: 4540. PMID 25105474 DOI: 10.1038/ncomms5540  0.88
2014 Tsagaratou A, Äijö T, Lio CW, Yue X, Huang Y, Jacobsen SE, Lähdesmäki H, Rao A. Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 111: E3306-15. PMID 25071199 DOI: 10.1073/pnas.1412327111  1
2014 Seumois G, Chavez L, Gerasimova A, Lienhard M, Omran N, Kalinke L, Vedanayagam M, Ganesan AP, Chawla A, Djukanović R, Ansel KM, Peters B, Rao A, Vijayanand P. Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility. Nature Immunology. 15: 777-88. PMID 24997565 DOI: 10.1038/ni.2937  0.88
2014 Carlson TJ, Pellerin A, Djuretic IM, Trivigno C, Koralov SB, Rao A, Sundrud MS. Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation. Journal of Immunology (Baltimore, Md. : 1950). 192: 2167-76. PMID 24489094 DOI: 10.4049/jimmunol.1302316  0.88
2014 Huang Y, Chavez L, Chang X, Wang X, Pastor WA, Kang J, Zepeda-Martínez JA, Pape UJ, Jacobsen SE, Peters B, Rao A. Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 1361-6. PMID 24474761 DOI: 10.1073/pnas.1322921111  1
2014 Iyer LM, Zhang D, de Souza RF, Pukkila PJ, Rao A, Aravind L. Lineage-specific expansions of TET/JBP genes and a new class of DNA transposons shape fungal genomic and epigenetic landscapes. Proceedings of the National Academy of Sciences of the United States of America. 111: 1676-83. PMID 24398522 DOI: 10.1073/pnas.1321818111  0.4
2014 Jeong M, Sun D, Luo M, Huang Y, Challen GA, Rodriguez B, Zhang X, Chavez L, Wang H, Hannah R, Kim SB, Yang L, Ko M, Chen R, Göttgens B, ... ... Rao A, et al. Large conserved domains of low DNA methylation maintained by Dnmt3a. Nature Genetics. 46: 17-23. PMID 24270360 DOI: 10.1038/ng.2836  0.88
2013 Tsagaratou A, Rao A. TET proteins and 5-methylcytosine oxidation in the immune system. Cold Spring Harbor Symposia On Quantitative Biology. 78: 1-10. PMID 24619230 DOI: 10.1101/sqb.2013.78.020248  0.64
2013 Vandenberghe M, Raphaël M, Lehen'kyi V, Gordienko D, Hastie R, Oddos T, Rao A, Hogan PG, Skryma R, Prevarskaya N. ORAI1 calcium channel orchestrates skin homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 110: E4839-48. PMID 24277812 DOI: 10.1073/pnas.1310394110  0.88
2013 Trifari S, Pipkin ME, Bandukwala HS, Äijö T, Bassein J, Chen R, Martinez GJ, Rao A. MicroRNA-directed program of cytotoxic CD8+ T-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 110: 18608-13. PMID 24163352 DOI: 10.1073/pnas.1317191110  0.48
2013 Fogli LK, Sundrud MS, Goel S, Bajwa S, Jensen K, Derudder E, Sun A, Coffre M, Uyttenhove C, Van Snick J, Schmidt-Supprian M, Rao A, Grunig G, Durbin J, Casola S, et al. T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia. Journal of Immunology (Baltimore, Md. : 1950). 191: 3100-11. PMID 23966625 DOI: 10.4049/jimmunol.1301360  0.88
2013 Zhou Y, Srinivasan P, Razavi S, Seymour S, Meraner P, Gudlur A, Stathopulos PB, Ikura M, Rao A, Hogan PG. Initial activation of STIM1, the regulator of store-operated calcium entry. Nature Structural & Molecular Biology. 20: 973-81. PMID 23851458 DOI: 10.1038/nsmb.2625  0.96
2013 Lister R, Mukamel EA, Nery JR, Urich M, Puddifoot CA, Johnson ND, Lucero J, Huang Y, Dwork AJ, Schultz MD, Yu M, Tonti-Filippini J, Heyn H, Hu S, Wu JC, ... Rao A, et al. Global epigenomic reconfiguration during mammalian brain development. Science (New York, N.Y.). 341: 1237905. PMID 23828890 DOI: 10.1126/science.1237905  0.88
2013 Blaschke K, Ebata KT, Karimi MM, Zepeda-Martínez JA, Goyal P, Mahapatra S, Tam A, Laird DJ, Hirst M, Rao A, Lorincz MC, Ramalho-Santos M. Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. Nature. 500: 222-6. PMID 23812591 DOI: 10.1038/nature12362  0.88
2013 Sharma S, Quintana A, Findlay GM, Mettlen M, Baust B, Jain M, Nilsson R, Rao A, Hogan PG. An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry. Nature. 499: 238-42. PMID 23792561 DOI: 10.1038/nature12229  0.96
2013 Pastor WA, Aravind L, Rao A. TETonic shift: biological roles of TET proteins in DNA demethylation and transcription. Nature Reviews. Molecular Cell Biology. 14: 341-56. PMID 23698584 DOI: 10.1038/nrm3589  0.88
2013 Ko M, An J, Bandukwala HS, Chavez L, Aijö T, Pastor WA, Segal MF, Li H, Koh KP, Lähdesmäki H, Hogan PG, Aravind L, Rao A. Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX. Nature. 497: 122-6. PMID 23563267 DOI: 10.1038/nature12052  0.88
2013 Oh-Hora M, Komatsu N, Pishyareh M, Feske S, Hori S, Taniguchi M, Rao A, Takayanagi H. Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry. Immunity. 38: 881-95. PMID 23499491 DOI: 10.1016/j.immuni.2013.02.008  0.64
2013 Balasubramani A, Rao A. O-GlcNAcylation and 5-methylcytosine oxidation: an unexpected association between OGT and TETs. Molecular Cell. 49: 618-9. PMID 23438858 DOI: 10.1016/j.molcel.2013.02.006  0.88
2013 Bandukwala HS, Rao A. 'Nurr'ishing Treg cells: Nr4a transcription factors control Foxp3 expression. Nature Immunology. 14: 201-3. PMID 23416671 DOI: 10.1038/ni.2546  0.48
2013 Vincent JJ, Huang Y, Chen PY, Feng S, Calvopiña JH, Nee K, Lee SA, Le T, Yoon AJ, Faull K, Fan G, Rao A, Jacobsen SE, Pellegrini M, Clark AT. Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells. Cell Stem Cell. 12: 470-8. PMID 23415914 DOI: 10.1016/j.stem.2013.01.016  1
2013 Yigit E, Zhang Q, Xi L, Grilley D, Widom J, Wang JP, Rao A, Pipkin ME. High-resolution nucleosome mapping of targeted regions using BAC-based enrichment. Nucleic Acids Research. 41: e87. PMID 23413004 DOI: 10.1093/nar/gkt081  0.88
2013 Gerasimova A, Chavez L, Li B, Seumois G, Greenbaum J, Rao A, Vijayanand P, Peters B. Predicting cell types and genetic variations contributing to disease by combining GWAS and epigenetic data. Plos One. 8: e54359. PMID 23382893 DOI: 10.1371/journal.pone.0054359  0.44
2013 Bronevetsky Y, Villarino AV, Eisley CJ, Barbeau R, Barczak AJ, Heinz GA, Kremmer E, Heissmeyer V, McManus MT, Erle DJ, Rao A, Ansel KM. T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire. The Journal of Experimental Medicine. 210: 417-32. PMID 23382546 DOI: 10.1084/jem.20111717  0.88
2013 Kang J, Kalantry S, Rao A. PGC7, H3K9me2 and Tet3: regulators of DNA methylation in zygotes. Cell Research. 23: 6-9. PMID 22868271 DOI: 10.1038/cr.2012.117  0.4
2012 Martinez GJ, Rao A. Immunology. Cooperative transcription factor complexes in control. Science (New York, N.Y.). 338: 891-2. PMID 23161983 DOI: 10.1126/science.1231310  0.48
2012 Huang Y, Rao A. New functions for DNA modifications by TET-JBP. Nature Structural & Molecular Biology. 19: 1061-4. PMID 23132381 DOI: 10.1038/nsmb.2437  1
2012 Pastor WA, Huang Y, Henderson HR, Agarwal S, Rao A. The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine. Nature Protocols. 7: 1909-17. PMID 23018194 DOI: 10.1038/nprot.2012.104  0.88
2012 Huang Y, Pastor WA, Zepeda-Martínez JA, Rao A. The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine. Nature Protocols. 7: 1897-908. PMID 23018193 DOI: 10.1038/nprot.2012.103  0.88
2012 Benson MJ, Aijö T, Chang X, Gagnon J, Pape UJ, Anantharaman V, Aravind L, Pursiheimo JP, Oberdoerffer S, Liu XS, Lahesmaa R, Lähdesmäki H, Rao A. Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) and elongation factor, RNA polymerase II, 2 (ELL2) are regulators of mRNA processing in plasma cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 16252-7. PMID 22991471 DOI: 10.1073/pnas.1214414109  0.88
2012 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, ... ... Rao A, et al. D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes & Development. 26: 2038-49. PMID 22925884 DOI: 10.1101/gad.198200.112  0.88
2012 Bandukwala HS, Gagnon J, Togher S, Greenbaum JA, Lamperti ED, Parr NJ, Molesworth AM, Smithers N, Lee K, Witherington J, Tough DF, Prinjha RK, Peters B, Rao A. Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 109: 14532-7. PMID 22912406 DOI: 10.1073/pnas.1212264109  0.88
2012 Keller TL, Zocco D, Sundrud MS, Hendrick M, Edenius M, Yum J, Kim YJ, Lee HK, Cortese JF, Wirth DF, Dignam JD, Rao A, Yeo CY, Mazitschek R, Whitman M. Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase. Nature Chemical Biology. 8: 311-7. PMID 22327401 DOI: 10.1038/nchembio.790  0.88
2012 Vijayanand P, Seumois G, Simpson LJ, Abdul-Wajid S, Baumjohann D, Panduro M, Huang X, Interlandi J, Djuretic IM, Brown DR, Sharpe AH, Rao A, Ansel KM. Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V. Immunity. 36: 175-87. PMID 22326582 DOI: 10.1016/j.immuni.2011.12.014  0.88
2012 Närvä E, Rahkonen N, Emani MR, Lund R, Pursiheimo JP, Nästi J, Autio R, Rasool O, Denessiouk K, Lähdesmäki H, Rao A, Lahesmaa R. RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation. Stem Cells (Dayton, Ohio). 30: 452-60. PMID 22162396 DOI: 10.1002/stem.1013  0.44
2011 Ko M, Rao A. TET2: epigenetic safeguard for HSC. Blood. 118: 4501-3. PMID 22033942 DOI: 10.1182/blood-2011-08-373357  0.32
2011 Ko M, Bandukwala HS, An J, Lamperti ED, Thompson EC, Hastie R, Tsangaratou A, Rajewsky K, Koralov SB, Rao A. Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 14566-71. PMID 21873190 DOI: 10.1073/pnas.1112317108  0.88
2011 Jankowska AM, Makishima H, Tiu RV, Szpurka H, Huang Y, Traina F, Visconte V, Sugimoto Y, Prince C, O'Keefe C, Hsi ED, List A, Sekeres MA, Rao A, McDevitt MA, et al. Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A. Blood. 118: 3932-41. PMID 21828135 DOI: 10.1182/blood-2010-10-311019  0.88
2011 Sharma S, Findlay GM, Bandukwala HS, Oberdoerffer S, Baust B, Li Z, Schmidt V, Hogan PG, Sacks DB, Rao A. Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex. Proceedings of the National Academy of Sciences of the United States of America. 108: 11381-6. PMID 21709260 DOI: 10.1073/pnas.1019711108  0.96
2011 Pastor WA, Pape UJ, Huang Y, Henderson HR, Lister R, Ko M, McLoughlin EM, Brudno Y, Mahapatra S, Kapranov P, Tahiliani M, Daley GQ, Liu XS, Ecker JR, Milos PM, ... ... Rao A, et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature. 473: 394-7. PMID 21552279 DOI: 10.1038/nature10102  0.88
2011 Bandukwala HS, Wu Y, Feuerer M, Chen Y, Barboza B, Ghosh S, Stroud JC, Benoist C, Mathis D, Rao A, Chen L. Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells. Immunity. 34: 479-91. PMID 21458306 DOI: 10.1016/j.immuni.2011.02.017  0.88
2011 Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, Nardone J, Laiho A, Tahiliani M, Sommer CA, Mostoslavsky G, Lahesmaa R, Orkin SH, Rodig SJ, Daley GQ, Rao A. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell. 8: 200-13. PMID 21295276 DOI: 10.1016/j.stem.2011.01.008  0.88
2011 Li H, Rao A, Hogan PG. Interaction of calcineurin with substrates and targeting proteins. Trends in Cell Biology. 21: 91-103. PMID 21115349 DOI: 10.1016/j.tcb.2010.09.011  0.96
2010 Pai BS, Agarwal S, Srinivasan G, Rao L, Rao AC. Metaplastic carcinoma breast (carcinosarcoma variant). The Indian Journal of Surgery. 72: 357-8. PMID 23133299 DOI: 10.1007/s12262-010-0104-6  1
2010 Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS, Aravind L, Agarwal S, Maciejewski JP, Rao A. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature. 468: 839-43. PMID 21057493 DOI: 10.1038/nature09586  0.88
2010 Rao A, Zhang Y, Muend S, Rao R. Mechanism of antifungal activity of terpenoid phenols resembles calcium stress and inhibition of the TOR pathway Antimicrobial Agents and Chemotherapy. 54: 5062-5069. PMID 20921304 DOI: 10.1128/AAC.01050-10  0.68
2010 Ghosh S, Koralov SB, Stevanovic I, Sundrud MS, Sasaki Y, Rajewsky K, Rao A, Müller MR. Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis Proceedings of the National Academy of Sciences of the United States of America. 107: 15169-15174. PMID 20696888 DOI: 10.1073/pnas.1009193107  0.88
2010 Pipkin ME, Rao A, Lichtenheld MG. The transcriptional control of the perforin locus. Immunological Reviews. 235: 55-72. PMID 20536555 DOI: 10.1111/j.0105-2896.2010.00905.x  0.44
2010 Hogan PG, Lewis RS, Rao A. Molecular basis of calcium signaling in lymphocytes: STIM and ORAI. Annual Review of Immunology. 28: 491-533. PMID 20307213 DOI: 10.1146/annurev.immunol.021908.132550  0.88
2010 Zhou Y, Ramachandran S, Oh-Hora M, Rao A, Hogan PG. Pore architecture of the ORAI1 store-operated calcium channel. Proceedings of the National Academy of Sciences of the United States of America. 107: 4896-901. PMID 20194792 DOI: 10.1073/pnas.1001169107  0.96
2010 Huang Y, Pastor WA, Shen Y, Tahiliani M, Liu DR, Rao A. The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing. Plos One. 5: e8888. PMID 20126651 DOI: 10.1371/journal.pone.0008888  0.88
2010 Pipkin ME, Sacks JA, Cruz-Guilloty F, Lichtenheld MG, Bevan MJ, Rao A. Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity. 32: 79-90. PMID 20096607 DOI: 10.1016/j.immuni.2009.11.012  0.88
2010 Zhou Y, Meraner P, Kwon HT, Machnes D, Oh-hora M, Zimmer J, Huang Y, Stura A, Rao A, Hogan PG. STIM1 gates the store-operated calcium channel ORAI1 in vitro. Nature Structural & Molecular Biology. 17: 112-6. PMID 20037597 DOI: 10.1038/nsmb.1724  0.88
2010 Fehr T, Lucas CL, Kurtz J, Onoe T, Zhao G, Hogan T, Vallot C, Rao A, Sykes M. A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo. Blood. 115: 1280-7. PMID 20007805 DOI: 10.1182/blood-2009-07-230680  0.88
2009 Djuretic IM, Cruz-Guilloty F, Rao A. Regulation of gene expression in peripheral T cells by Runx transcription factors. Advances in Immunology. 104: 1-23. PMID 20457114 DOI: 10.1016/S0065-2776(08)04001-7  0.88
2009 McCarl CA, Picard C, Khalil S, Kawasaki T, Röther J, Papolos A, Kutok J, Hivroz C, Ledeist F, Plogmann K, Ehl S, Notheis G, Albert MH, Belohradsky BH, Kirschner J, ... Rao A, et al. ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia. The Journal of Allergy and Clinical Immunology. 124: 1311-1318.e7. PMID 20004786 DOI: 10.1016/j.jaci.2009.10.007  0.88
2009 Koh KP, Sundrud MS, Rao A. Domain requirements and sequence specificity of DNA binding for the forkhead transcription factor FOXP3. Plos One. 4: e8109. PMID 19956618 DOI: 10.1371/journal.pone.0008109  0.88
2009 Rao A, Hogan PG. Calcium signaling in cells of the immune and hematopoietic systems. Immunological Reviews. 231: 5-9. PMID 19754886 DOI: 10.1111/j.1600-065X.2009.00823.x  0.96
2009 Pipkin ME, Rao A. SnapShot: effector and memory T cell differentiation. Cell. 138: 606.e1-2. PMID 19665979 DOI: 10.1016/j.cell.2009.07.020  0.44
2009 Sharma S, Rao A. RNAi screening: tips and techniques. Nature Immunology. 10: 799-804. PMID 19621037 DOI: 10.1038/ni0809-799  0.48
2009 Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A. Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response. Science (New York, N.Y.). 324: 1334-8. PMID 19498172 DOI: 10.1126/science.1172638  0.88
2009 Picard C, McCarl CA, Papolos A, Khalil S, Lüthy K, Hivroz C, LeDeist F, Rieux-Laucat F, Rechavi G, Rao A, Fischer A, Feske S. STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity. The New England Journal of Medicine. 360: 1971-80. PMID 19420366 DOI: 10.1056/NEJMoa0900082  0.88
2009 Iyer LM, Tahiliani M, Rao A, Aravind L. Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. Cell Cycle (Georgetown, Tex.). 8: 1698-710. PMID 19411852  0.72
2009 Oh-hora M, Rao A. The calcium/NFAT pathway: role in development and function of regulatory T cells. Microbes and Infection / Institut Pasteur. 11: 612-9. PMID 19375514 DOI: 10.1016/j.micinf.2009.04.008  0.64
2009 Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (New York, N.Y.). 324: 930-5. PMID 19372391 DOI: 10.1126/science.1170116  0.88
2009 Müller MR, Sasaki Y, Stevanovic I, Lamperti ED, Ghosh S, Sharma S, Gelinas C, Rossi DJ, Pipkin ME, Rajewsky K, Hogan PG, Rao A. Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development. Proceedings of the National Academy of Sciences of the United States of America. 106: 7034-9. PMID 19351896 DOI: 10.1073/pnas.0813296106  0.88
2009 Cruz-Guilloty F, Pipkin ME, Djuretic IM, Levanon D, Lotem J, Lichtenheld MG, Groner Y, Rao A. Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs. The Journal of Experimental Medicine. 206: 51-9. PMID 19139168 DOI: 10.1084/jem.20081242  0.88
2009 Mayoral RJ, Pipkin ME, Pachkov M, van Nimwegen E, Rao A, Monticelli S. MicroRNA-221-222 regulate the cell cycle in mast cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 433-45. PMID 19109175  0.48
2008 Bandukwala H, Sundrud MS, Rao A. Orphans against autoimmunity. Immunity. 29: 167-8. PMID 18701076 DOI: 10.1016/j.immuni.2008.07.008  0.88
2008 Oberdoerffer S, Moita LF, Neems D, Freitas RP, Hacohen N, Rao A. Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL. Science (New York, N.Y.). 321: 686-91. PMID 18669861 DOI: 10.1126/science.1157610  0.48
2008 Horng T, Oberdoerffer S, Rao A. Gene regulation and signal transduction in the immune system. Genome Biology. 9: 315. PMID 18644102 DOI: 10.1186/gb-2008-9-7-315  0.48
2008 Gwack Y, Srikanth S, Oh-Hora M, Hogan PG, Lamperti ED, Yamashita M, Gelinas C, Neems DS, Sasaki Y, Feske S, Prakriya M, Rajewsky K, Rao A. Hair loss and defective T- and B-cell function in mice lacking ORAI1. Molecular and Cellular Biology. 28: 5209-22. PMID 18591248 DOI: 10.1128/MCB.00360-08  0.88
2008 Oh-hora M, Rao A. Calcium signaling in lymphocytes. Current Opinion in Immunology. 20: 250-8. PMID 18515054 DOI: 10.1016/j.coi.2008.04.004  0.64
2008 Barr VA, Bernot KM, Srikanth S, Gwack Y, Balagopalan L, Regan CK, Helman DJ, Sommers CL, Oh-Hora M, Rao A, Samelson LE. Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps. Molecular Biology of the Cell. 19: 2802-17. PMID 18448669 DOI: 10.1091/mbc.E08-02-0146  0.88
2008 Ansel KM, Pastor WA, Rath N, Lapan AD, Glasmacher E, Wolf C, Smith LC, Papadopoulou N, Lamperti ED, Tahiliani M, Ellwart JW, Shi Y, Kremmer E, Rao A, Heissmeyer V. Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing. Nature Structural & Molecular Biology. 15: 523-30. PMID 18438418 DOI: 10.1038/nsmb.1417  0.88
2008 Oh-Hora M, Yamashita M, Hogan PG, Sharma S, Lamperti E, Chung W, Prakriya M, Feske S, Rao A. Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance. Nature Immunology. 9: 432-43. PMID 18327260 DOI: 10.1038/ni1574  0.88
2008 Heissmeyer V, Rao A. Itching to end NF-kappaB. Nature Immunology. 9: 227-9. PMID 18285770 DOI: 10.1038/ni0308-227  0.36
2008 Sundrud MS, Rao A. Regulation of T helper 17 differentiation by orphan nuclear receptors: it's not just ROR gamma t anymore. Immunity. 28: 5-7. PMID 18199410 DOI: 10.1016/j.immuni.2007.12.006  0.88
2007 Carvalho LD, Teixeira LK, Carrossini N, Caldeira AT, Ansel KM, Rao A, Viola JP. The NFAT1 transcription factor is a repressor of cyclin A2 gene expression. Cell Cycle (Georgetown, Tex.). 6: 1789-95. PMID 17637565  0.88
2007 Hu H, Djuretic I, Sundrud MS, Rao A. Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT. Trends in Immunology. 28: 329-32. PMID 17618833 DOI: 10.1016/  0.88
2007 Gwack Y, Feske S, Srikanth S, Hogan PG, Rao A. Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes. Cell Calcium. 42: 145-56. PMID 17572487 DOI: 10.1016/j.ceca.2007.03.007  0.96
2007 Li H, Zhang L, Rao A, Harrison SC, Hogan PG. Structure of calcineurin in complex with PVIVIT peptide: portrait of a low-affinity signalling interaction. Journal of Molecular Biology. 369: 1296-306. PMID 17498738 DOI: 10.1016/j.jmb.2007.04.032  0.88
2007 Tahiliani M, Mei P, Fang R, Leonor T, Rutenberg M, Shimizu F, Li J, Rao A, Shi Y. The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature. 447: 601-5. PMID 17468742 DOI: 10.1038/nature05823  0.72
2007 Thai TH, Calado DP, Casola S, Ansel KM, Xiao C, Xue Y, Murphy A, Frendewey D, Valenzuela D, Kutok JL, Schmidt-Supprian M, Rajewsky N, Yancopoulos G, Rao A, Rajewsky K. Regulation of the germinal center response by microRNA-155. Science (New York, N.Y.). 316: 604-8. PMID 17463289 DOI: 10.1126/science.1141229  0.88
2007 Hogan PG, Rao A. Dissecting ICRAC, a store-operated calcium current. Trends in Biochemical Sciences. 32: 235-45. PMID 17434311 DOI: 10.1016/j.tibs.2007.03.009  0.96
2007 Sundrud MS, Rao A. New twists of T cell fate: control of T cell activation and tolerance by TGF-beta and NFAT. Current Opinion in Immunology. 19: 287-93. PMID 17433870 DOI: 10.1016/j.coi.2007.04.014  0.88
2007 Sundrud MS, Rao A. Regulatory T-cell gene expression: ChIP'ing away at Foxp3. Immunology and Cell Biology. 85: 177-8. PMID 17353928 DOI: 10.1038/sj.icb.7100051  0.88
2007 Gwack Y, Srikanth S, Feske S, Cruz-Guilloty F, Oh-hora M, Neems DS, Hogan PG, Rao A. Biochemical and functional characterization of Orai proteins. The Journal of Biological Chemistry. 282: 16232-43. PMID 17293345 DOI: 10.1074/jbc.M609630200  0.88
2007 Pipkin ME, Ljutic B, Cruz-Guilloty F, Nouzova M, Rao A, Zúñiga-Pflücker JC, Lichtenheld MG. Chromosome transfer activates and delineates a locus control region for perforin. Immunity. 26: 29-41. PMID 17222571 DOI: 10.1016/j.immuni.2006.11.009  0.88
2007 Djuretic IM, Levanon D, Negreanu V, Groner Y, Rao A, Ansel KM. Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. Nature Immunology. 8: 145-53. PMID 17195845 DOI: 10.1038/ni1424  0.84
2006 Prakriya M, Feske S, Gwack Y, Srikanth S, Rao A, Hogan PG. Orai1 is an essential pore subunit of the CRAC channel. Nature. 443: 230-3. PMID 16921383 DOI: 10.1038/nature05122  0.88
2006 Monticelli S, Sharma S, Rao A. Immunological applications of genomics. Genome Biology. 7: 321. PMID 16879724 DOI: 10.1186/gb-2006-7-7-321  0.48
2006 Wu Y, Borde M, Heissmeyer V, Feuerer M, Lapan AD, Stroud JC, Bates DL, Guo L, Han A, Ziegler SF, Mathis D, Benoist C, Chen L, Rao A. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell. 126: 375-87. PMID 16873067 DOI: 10.1016/j.cell.2006.05.042  0.88
2006 Barrington RA, Borde M, Rao A, Carroll MC. Involvement of NFAT1 in B cell self-tolerance. Journal of Immunology (Baltimore, Md. : 1950). 177: 1510-5. PMID 16849457  0.88
2006 Hu H, Wang B, Borde M, Nardone J, Maika S, Allred L, Tucker PW, Rao A. Foxp1 is an essential transcriptional regulator of B cell development. Nature Immunology. 7: 819-26. PMID 16819554 DOI: 10.1038/ni1358  0.88
2006 Borde M, Barrington RA, Heissmeyer V, Carroll MC, Rao A. Transcriptional basis of lymphocyte tolerance. Immunological Reviews. 210: 105-19. PMID 16623767 DOI: 10.1111/j.0105-2896.2006.00370.x  0.88
2006 Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, Hogan PG, Lewis RS, Daly M, Rao A. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature. 441: 179-85. PMID 16582901 DOI: 10.1038/nature04702  0.88
2006 Ansel KM, Djuretic I, Tanasa B, Rao A. Regulation of Th2 differentiation and Il4 locus accessibility. Annual Review of Immunology. 24: 607-56. PMID 16551261 DOI: 10.1146/annurev.immunol.23.021704.115821  0.88
2006 Gwack Y, Sharma S, Nardone J, Tanasa B, Iuga A, Srikanth S, Okamura H, Bolton D, Feske S, Hogan PG, Rao A. A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT. Nature. 441: 646-50. PMID 16511445 DOI: 10.1038/nature04631  0.88
2005 Monticelli S, Ansel KM, Lee DU, Rao A. Regulation of gene expression in mast cells: micro-rNA expression and chromatin structural analysis of cytokine genes. Novartis Foundation Symposium. 271: 179-87; discussion 1. PMID 16605135  0.88
2005 Kumar L, Feske S, Rao A, Geha RS. A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function. Proceedings of the National Academy of Sciences of the United States of America. 102: 19063-8. PMID 16354835 DOI: 10.1073/pnas.0509176102  0.64
2005 Monticelli S, Lee DU, Nardone J, Bolton DL, Rao A. Chromatin-based regulation of cytokine transcription in Th2 cells and mast cells. International Immunology. 17: 1513-24. PMID 16199489 DOI: 10.1093/intimm/dxh329  0.88
2005 Kang S, Li H, Rao A, Hogan PG. Inhibition of the calcineurin-NFAT interaction by small organic molecules reflects binding at an allosteric site. The Journal of Biological Chemistry. 280: 37698-706. PMID 16148011 DOI: 10.1074/jbc.M502247200  0.96
2005 Feske S, Prakriya M, Rao A, Lewis RS. A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. The Journal of Experimental Medicine. 202: 651-62. PMID 16147976 DOI: 10.1084/jem.20050687  0.88
2005 Monticelli S, Ansel KM, Xiao C, Socci ND, Krichevsky AM, Thai TH, Rajewsky N, Marks DS, Sander C, Rajewsky K, Rao A, Kosik KS. MicroRNA profiling of the murine hematopoietic system. Genome Biology. 6: R71. PMID 16086853 DOI: 10.1186/gb-2005-6-8-r71  0.88
2005 Esensten JH, Tsytsykova AV, Lopez-Rodriguez C, Ligeiro FA, Rao A, Goldfeld AE. NFAT5 binds to the TNF promoter distinctly from NFATp, c, 3 and 4, and activates TNF transcription during hypertonic stress alone. Nucleic Acids Research. 33: 3845-54. PMID 16027109 DOI: 10.1093/nar/gki701  0.88
2005 Muljo SA, Ansel KM, Kanellopoulou C, Livingston DM, Rao A, Rajewsky K. Aberrant T cell differentiation in the absence of Dicer. The Journal of Experimental Medicine. 202: 261-9. PMID 16009718 DOI: 10.1084/jem.20050678  0.88
2005 Heissmeyer V, Macián F, Varma R, Im SH, García-Cozar F, Horton HF, Byrne MC, Feske S, Venuprasad K, Gu H, Liu YC, Dustin ML, Rao A. A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling. Novartis Foundation Symposium. 267: 165-74; discussion 1. PMID 15999806  0.88
2005 Heissmeyer V, Ansel KM, Rao A. A plague of autoantibodies. Nature Immunology. 6: 642-4. PMID 15991362 DOI: 10.1038/ni1214  0.88
2005 Oberdoerffer P, Kanellopoulou C, Heissmeyer V, Paeper C, Borowski C, Aifantis I, Rao A, Rajewsky K. Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages Molecular and Cellular Biology. 25: 3896-3905. PMID 15870264 DOI: 10.1128/MCB.25.10.3896-3905.2005  0.88
2005 Benedito AB, Lehtinen M, Massol R, Lopes UG, Kirchhausen T, Rao A, Bonni A. The transcription factor NFAT3 mediates neuronal survival. The Journal of Biological Chemistry. 280: 2818-25. PMID 15537643 DOI: 10.1074/jbc.M408741200  0.88
2004 Ansel KM, Greenwald RJ, Agarwal S, Bassing CH, Monticelli S, Interlandi J, Djuretic IM, Lee DU, Sharpe AH, Alt FW, Rao A. Deletion of a conserved Il4 silencer impairs T helper type 1-mediated immunity. Nature Immunology. 5: 1251-9. PMID 15516924 DOI: 10.1038/ni1135  0.88
2004 Lee DU, Rao A. Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3. Proceedings of the National Academy of Sciences of the United States of America. 101: 16010-5. PMID 15507491 DOI: 10.1073/pnas.0407031101  0.56
2004 Monticelli S, Solymar DC, Rao A. Role of NFAT proteins in IL13 gene transcription in mast cells. The Journal of Biological Chemistry. 279: 36210-8. PMID 15229217 DOI: 10.1074/jbc.M406354200  0.88
2004 Heissmeyer V, Macián F, Im SH, Varma R, Feske S, Venuprasad K, Gu H, Liu YC, Dustin ML, Rao A. Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins. Nature Immunology. 5: 255-65. PMID 14973438 DOI: 10.1038/ni1047  0.64
2003 Feske S, Okamura H, Hogan PG, Rao A. Ca2+/calcineurin signalling in cells of the immune system. Biochemical and Biophysical Research Communications. 311: 1117-32. PMID 14623298  0.96
2003 Syken J, Macian F, Agarwal S, Rao A, Münger K. TID1, a mammalian homologue of the drosophila tumor suppressor lethal(2) tumorous imaginal discs, regulates activation-induced cell death in Th2 cells. Oncogene. 22: 4636-41. PMID 12879007 DOI: 10.1038/sj.onc.1206569  0.88
2002 Rao AV. Lycopene, tomatoes, and the prevention of coronary heart disease Experimental Biology and Medicine. 227: 908-913. PMID 12424333  1
2002 Solymar DC, Agarwal S, Bassing CH, Alt FW, Rao A. A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. Immunity. 17: 41-50. PMID 12150890 DOI: 10.1016/S1074-7613(02)00334-5  0.88
2002 Lee DU, Agarwal S, Rao A. Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene. Immunity. 16: 649-60. PMID 12049717  1
2001 Agarwal A, Shen H, Agarwal S, Rao AV. Lycopene Content of Tomato Products: Its Stability, Bioavailability and In Vivo Antioxidant Properties. Journal of Medicinal Food. 4: 9-15. PMID 12639283 DOI: 10.1089/10966200152053668  1
2001 Rao A. New functions for DNA binding domains Science"S Stke [Electronic Resource] : Signal Transduction Knowledge Environment. 2001. PMID 11752650  0.88
2000 Rao AV, Shen H, Agarwal A, Yatcilla MT, Agarwal S. Bioabsorption and in vivo antioxidant properties of grape extract biovin((r)): a human intervention study. Journal of Medicinal Food. 3: 15-22. PMID 19281340 DOI: 10.1089/jmf.2000.3.15  1
2000 Agarwal S, Rao AV. Carotenoids and chronic diseases. Drug Metabolism and Drug Interactions. 17: 189-210. PMID 11201295  1
2000 Jenkins DJ, Kendall CW, Vidgen E, Vuksan V, Jackson CJ, Augustin LS, Lee B, Garsetti M, Agarwal S, Rao AV, Cagampang GB, Fulgoni V. Effect of soy-based breakfast cereal on blood lipids and oxidized low-density lipoprotein. Metabolism: Clinical and Experimental. 49: 1496-500. PMID 11092518 DOI: 10.1053/meta.2000.17703  1
2000 Rao AV, Agarwal S. Role of antioxidant lycopene in cancer and heart disease. Journal of the American College of Nutrition. 19: 563-9. PMID 11022869  1
2000 Agarwal S, Rao AV. Tomato lycopene and its role in human health and chronic diseases. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 163: 739-44. PMID 11022591  1
2000 Agarwal S, Avni O, Rao A. Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo. Immunity. 12: 643-52. PMID 10894164  0.88
2000 Jenkins DJ, Kendall CW, Garsetti M, Rosenberg-Zand RS, Jackson CJ, Agarwal S, Rao AV, Diamandis EP, Parker T, Faulkner D, Vuksan V, Vidgen E. Effect of soy protein foods on low-density lipoprotein oxidation and ex vivo sex hormone receptor activity--a controlled crossover trial. Metabolism: Clinical and Experimental. 49: 537-43. PMID 10778882 DOI: 10.1016/S0026-0495(00)80022-0  1
2000 Jenkins DJ, Kendall CW, Vidgen E, Mehling CC, Parker T, Seyler H, Faulkner D, Garsetti M, Griffin LC, Agarwal S, Rao AV, Cunnane SC, Ryan MA, Connelly PW, Leiter LA, et al. The effect on serum lipids and oxidized low-density lipoprotein of supplementing self-selected low-fat diets with soluble-fiber, soy, and vegetable protein foods. Metabolism: Clinical and Experimental. 49: 67-72. PMID 10647066 DOI: 10.1016/S0026-0495(00)90738-8  1
1999 Jenkins DJ, Kendall CW, Mehling CC, Parker T, Rao AV, Agarwal S, Novokmet R, Jones PJ, Raeini M, Story JA, Furumoto E, Vidgen E, Griffin LC, Cunnane SC, Ryan MA, et al. Combined effect of vegetable protein (soy) and soluble fiber added to a standard cholesterol-lowering diet. Metabolism: Clinical and Experimental. 48: 809-16. PMID 10381159 DOI: 10.1016/S0026-0495(99)90184-1  1
1999 Hecht SS, Kenney PM, Wang M, Trushin N, Agarwal S, Rao AV, Upadhyaya P. Evaluation of butylated hydroxyanisole, myo-inositol, curcumin, esculetin, resveratrol and lycopene as inhibitors of benzo[a]pyrene plus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice. Cancer Letters. 137: 123-30. PMID 10374832 DOI: 10.1016/S0304-3835(98)00326-7  1
1999 Rao AV, Fleshner N, Agarwal S. Serum and tissue lycopene and biomarkers of oxidation in prostate cancer patients: a case-control study. Nutrition and Cancer. 33: 159-64. PMID 10368811 DOI: 10.1207/S15327914NC330207  1
1999 Agarwal S, Viola JP, Rao A. Chromatin-based regulatory mechanisms governing cytokine gene transcription. The Journal of Allergy and Clinical Immunology. 103: 990-9. PMID 10359875 DOI: 10.1016/S0091-6749(99)70168-5  1
1999 Jenkins DJ, Kendall CW, Vidgen E, Agarwal S, Rao AV, Rosenberg RS, Diamandis EP, Novokmet R, Mehling CC, Perera T, Griffin LC, Cunnane SC. Health aspects of partially defatted flaxseed, including effects on serum lipids, oxidative measures, and ex vivo androgen and progestin activity: a controlled crossover trial. The American Journal of Clinical Nutrition. 69: 395-402. PMID 10075322 DOI: 10.1093/ajcn/69.3.395  1
1998 Agarwal S, Rao A. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity. 9: 765-75. PMID 9881967  1
1998 Agarwal S, Rao AV. Tomato lycopene and low density lipoprotein oxidation: a human dietary intervention study. Lipids. 33: 981-4. PMID 9832077  1
1998 Rao AV, Agarwal S. Bioavailability and in vivo antioxidant properties of lycopene from tomato products and their possible role in the prevention of cancer. Nutrition and Cancer. 31: 199-203. PMID 9795972 DOI: 10.1080/01635589809514703  0.96
1998 Agarwal S, Rao A. Long-range transcriptional regulation of cytokine gene expression. Current Opinion in Immunology. 10: 345-52. PMID 9638372  1
1995 Rao A. NFATp, a cyclosporin-sensitive transcription factor implicated in cytokine gene induction Journal of Leukocyte Biology. 57: 536-542. PMID 7722411  0.88
1994 Rao A. NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes Immunology Today. 15: 274-281. PMID 8068174 DOI: 10.1016/0167-5699(94)90007-8  0.88
1993 Rao AV, Friday D, Janezic SA, Kendall CW. Influence of dietary cholesterol on facal steroid excretion and its impact on the colonic epithelium in mice: Implications for colon carcinogenesis Nutrition Research. 13: 45-57. DOI: 10.1016/S0271-5317(05)80655-4  1
1991 Rao A. Signaling mechanisms in T cells Critical Reviews in Immunology. 10: 495-519. PMID 1650561  0.88
1979 Rao A. Disposition of the band 3 polypeptide in the human erythrocyte membrane. The reactive sulfhydryl groups Journal of Biological Chemistry. 254: 3503-3511. PMID 429367  0.88
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