Year |
Citation |
Score |
2017 |
Nagendra Reddy C, Ye Q, Patel P, Sivendran S, Chourey S, Wang R, Anumolu JR, Grant GE, Powell WS, Rokach J. Design and synthesis of affinity chromatography ligands for the purification of 5-hydroxyeicosanoid dehydrogenase. Bioorganic & Medicinal Chemistry. 25: 116-125. PMID 28340986 DOI: 10.1016/J.Bmc.2016.10.017 |
0.763 |
|
2014 |
Patel P, Reddy CN, Gore V, Chourey S, Ye Q, Ouedraogo YP, Gravel S, Powell WS, Rokach J. Two Potent OXE-R Antagonists: Assignment of Stereochemistry. Acs Medicinal Chemistry Letters. 5: 815-9. PMID 25050171 DOI: 10.1021/Ml500161V |
0.784 |
|
2014 |
Gore V, Chourey S, Ye Q, Patel P, Ouedraogo Y, Gravel S, Powell WS, Rokach J. Base-dependent formation of cis and trans olefins and their application in the synthesis of 5-oxo-ETE receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 24: 3385-8. PMID 24948567 DOI: 10.1016/J.Bmcl.2014.05.090 |
0.748 |
|
2014 |
Gore V, Gravel S, Cossette C, Patel P, Chourey S, Ye Q, Rokach J, Powell WS. Inhibition of 5-oxo-6,8,11,14-eicosatetraenoic acid-induced activation of neutrophils and eosinophils by novel indole OXE receptor antagonists. Journal of Medicinal Chemistry. 57: 364-77. PMID 24351031 DOI: 10.1021/Jm401292M |
0.764 |
|
2013 |
Gore V, Patel P, Chang CT, Sivendran S, Kang N, Ouedraogo YP, Gravel S, Powell WS, Rokach J. 5-Oxo-ETE receptor antagonists. Journal of Medicinal Chemistry. 56: 3725-32. PMID 23581530 DOI: 10.1021/Jm400480J |
0.7 |
|
2011 |
Grant GE, Rubino S, Gravel S, Wang X, Patel P, Rokach J, Powell WS. Enhanced formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by cancer cells in response to oxidative stress, docosahexaenoic acid and neutrophil-derived 5-hydroxy-6,8,11,14-eicosatetraenoic acid. Carcinogenesis. 32: 822-8. PMID 21393477 DOI: 10.1093/Carcin/Bgr044 |
0.603 |
|
2011 |
Patel P, Gore V, Powell WS, Rokach J. C20-trifluoro-5-oxo-ETE: a metabolically stable 5-oxo-ETE derivative. Bioorganic & Medicinal Chemistry Letters. 21: 1987-90. PMID 21377873 DOI: 10.1016/J.Bmcl.2011.02.021 |
0.718 |
|
2011 |
Grant GE, Gravel S, Guay J, Patel P, Mazer BD, Rokach J, Powell WS. 5-oxo-ETE is a major oxidative stress-induced arachidonate metabolite in B lymphocytes. Free Radical Biology & Medicine. 50: 1297-304. PMID 21334434 DOI: 10.1016/J.Freeradbiomed.2011.02.010 |
0.607 |
|
2011 |
Patel P, Anumolu JR, Powell WS, Rokach J. 5-oxo-15-HETE: total synthesis and bioactivity. Bioorganic & Medicinal Chemistry Letters. 21: 1857-60. PMID 21316960 DOI: 10.1016/J.Bmcl.2011.01.032 |
0.57 |
|
2009 |
Chang CT, Patel P, Gore V, Song WL, Lawson JA, Powell WS, Fitzgerald GA, Rokach J. A new approach to the synthesis of polyunsaturated deuterated isoprostanes: total synthesis of d4-5-epi-8,12-iso-iPF3alpha-VI and d4-8,12-iso-iPF3alpha-VI. Bioorganic & Medicinal Chemistry Letters. 19: 6755-8. PMID 19846297 DOI: 10.1016/J.Bmcl.2009.09.099 |
0.746 |
|
2009 |
Song WL, Paschos G, Fries S, Reilly MP, Yu Y, Rokach J, Chang CT, Patel P, Lawson JA, Fitzgerald GA. Novel eicosapentaenoic acid-derived F3-isoprostanes as biomarkers of lipid peroxidation. The Journal of Biological Chemistry. 284: 23636-43. PMID 19520854 DOI: 10.1074/Jbc.M109.024075 |
0.657 |
|
2009 |
Patel P, Cossette C, Anumolu JR, Erlemann KR, Grant GE, Rokach J, Powell WS. Substrate selectivity of 5-hydroxyeicosanoid dehydrogenase and its inhibition by 5-hydroxy-Delta6-long-chain fatty acids. The Journal of Pharmacology and Experimental Therapeutics. 329: 335-41. PMID 19164464 DOI: 10.1124/Jpet.108.143453 |
0.651 |
|
2008 |
Chang CT, Patel P, Kang N, Lawson JA, Song WL, Powell WS, FitzGerald GA, Rokach J. Eicosapentaenoic-acid-derived isoprostanes: synthesis and discovery of two major isoprostanes. Bioorganic & Medicinal Chemistry Letters. 18: 5523-7. PMID 18804370 DOI: 10.1016/J.Bmcl.2008.09.008 |
0.729 |
|
2008 |
Patel P, Lee GJ, Kim S, Grant GE, Powell WS, Rokach J. Enantio- and stereospecific syntheses of 15(R)-Me-PGD2, a potent and selective DP2-receptor agonist. The Journal of Organic Chemistry. 73: 7213-8. PMID 18700746 DOI: 10.1021/Jo801190M |
0.619 |
|
2008 |
Patel P, Cossette C, Anumolu JR, Gravel S, Lesimple A, Mamer OA, Rokach J, Powell WS. Structural requirements for activation of the 5-oxo-6E,8Z, 11Z,14Z-eicosatetraenoic acid (5-oxo-ETE) receptor: identification of a mead acid metabolite with potent agonist activity. The Journal of Pharmacology and Experimental Therapeutics. 325: 698-707. PMID 18292294 DOI: 10.1124/Jpet.107.134908 |
0.618 |
|
2008 |
Cossette C, Patel P, Anumolu JR, Sivendran S, Lee GJ, Gravel S, Graham FD, Lesimple A, Mamer OA, Rokach J, Powell WS. Human neutrophils convert the sebum-derived polyunsaturated fatty acid Sebaleic acid to a potent granulocyte chemoattractant. The Journal of Biological Chemistry. 283: 11234-43. PMID 18287092 DOI: 10.1074/Jbc.M709531200 |
0.756 |
|
2007 |
Patel P, Chang CT, Kang N, Lee GJ, Powell WS, Rokach J. Reductive Deprotection of Silyl Groups with Wilkinson's Catalyst/Catechol Borane. Tetrahedron Letters. 48: 5289-5292. PMID 18037973 DOI: 10.1016/J.Tetlet.2007.05.118 |
0.674 |
|
2007 |
Erlemann KR, Cossette C, Grant GE, Lee GJ, Patel P, Rokach J, Powell WS. Regulation of 5-hydroxyeicosanoid dehydrogenase activity in monocytic cells. The Biochemical Journal. 403: 157-65. PMID 17166093 DOI: 10.1042/Bj20061617 |
0.586 |
|
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