| Year |
Citation |
Score |
| 2023 |
Hwang Y, Yun HJ, Jeong JW, Kim M, Joo S, Lee HK, Chang HS, Kim SM, Fang S. Co-inhibition of glutaminolysis and one-carbon metabolism promotes ROS accumulation leading to enhancement of chemotherapeutic efficacy in anaplastic thyroid cancer. Cell Death & Disease. 14: 515. PMID 37573361 DOI: 10.1038/s41419-023-06041-2 |
0.342 |
|
| 2022 |
Shim S, Krishnaiah M, Sankham MR, Kim I, Lee Y, Shin I, Oh AR, Lee HJ, Vu TNL, Park J, Choi S, Park S, Kwon Y, Fang S, Kim DK. Discovery of ()-3-(3-((2-Cyano-4'-dimethylaminobiphenyl-4-ylmethyl)cyclohexanecarbonylamino)-5-fluorophenyl)acrylic Acid Methyl Ester, an Intestine-Specific, FXR Partial Agonist for the Treatment of Nonalcoholic Steatohepatitis. Journal of Medicinal Chemistry. PMID 35797110 DOI: 10.1021/acs.jmedchem.2c00641 |
0.366 |
|
| 2019 |
Oh SK, Kim D, Kim K, Boo K, Yu YS, Kim IS, Jeon Y, Im SK, Lee SH, Lee JM, Ko Y, Lee H, Park D, Fang S, Baek SH. RORα is crucial for attenuated inflammatory response to maintain intestinal homeostasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570593 DOI: 10.1073/Pnas.1907595116 |
0.347 |
|
| 2019 |
Jang SI, Fang S, Kim KP, Ko Y, Kim H, Oh J, Hong GY, Lee SY, Kim JM, Noh I, Lee DK. Combination treatment with n-3 polyunsaturated fatty acids and ursodeoxycholic acid dissolves cholesterol gallstones in mice. Scientific Reports. 9: 12740. PMID 31484954 DOI: 10.1038/s41598-019-49095-z |
0.303 |
|
| 2018 |
Kim H, Fang S. Crosstalk between FXR and TGR5 controls glucagon-like peptide 1 secretion to maintain glycemic homeostasis. Laboratory Animal Research. 34: 140-146. PMID 30671099 DOI: 10.5625/lar.2018.34.4.140 |
0.4 |
|
| 2018 |
Hong SH, Fang S, Lu BC, Nofsinger R, Kawakami Y, Castro GL, Yin Y, Lin C, Yu RT, Downes M, Izpisúa Belmonte JC, Shilatifard A, Evans RM. Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30254164 DOI: 10.1073/Pnas.1809480115 |
0.38 |
|
| 2017 |
Kim K, Boo K, Yu YS, Oh SK, Kim H, Jeon Y, Bhin J, Hwang D, Kim KI, Lee JS, Im SS, Yoon SG, Kim IY, Seong JK, Lee H, ... Fang S, et al. RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network. Nature Communications. 8: 162. PMID 28757615 DOI: 10.1038/S41467-017-00215-1 |
0.532 |
|
| 2017 |
Fang S. Bile Acid Receptor Farnesoid X Receptor: A Novel Therapeutic Target for Metabolic Diseases Journal of Lipid and Atherosclerosis. 6: 1. DOI: 10.12997/JLA.2017.6.1.1 |
0.351 |
|
| 2016 |
Kim SG, Kim BK, Kim K, Fang S. Bile Acid Nuclear Receptor Farnesoid X Receptor: Therapeutic Target for Nonalcoholic Fatty Liver Disease. Endocrinology and Metabolism (Seoul, Korea). 31: 500-504. PMID 28029021 DOI: 10.3803/EnM.2016.31.4.500 |
0.437 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... Fang S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.589 |
|
| 2016 |
Han B, Kim BK, Kim K, Fang S. Essential roles of bile acids and their nuclear receptors, FXR and PXR, in the cholestatic liver disease Animal Cells and Systems. 20: 175-178. DOI: 10.1080/19768354.2016.1211175 |
0.385 |
|
| 2015 |
Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature Medicine. 21: 159-65. PMID 25559344 DOI: 10.1038/Nm.3760 |
0.375 |
|
| 2015 |
Kim YC, Fang S, Byun S, Seok S, Kemper B, Kemper JK. Farnesoid X receptor-induced lysine-specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicity. Hepatology (Baltimore, Md.). 62: 220-31. PMID 25545350 DOI: 10.1002/Hep.27677 |
0.757 |
|
| 2014 |
Jacinto S, Fang S. Essential roles of bile acid receptors FXR and TGR5 as metabolic regulators Animal Cells and Systems. 18: 359-364. DOI: 10.1080/19768354.2014.987318 |
0.439 |
|
| 2011 |
Fang S, Suh JM, Atkins AR, Hong SH, Leblanc M, Nofsinger RR, Yu RT, Downes M, Evans RM. Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 108: 3412-7. PMID 21300871 DOI: 10.1073/Pnas.1017707108 |
0.389 |
|
| 2011 |
Kanamaluru D, Xiao Z, Fang S, Choi SE, Kim DH, Veenstra TD, Kemper JK. Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner. Molecular and Cellular Biology. 31: 1540-50. PMID 21262773 DOI: 10.1128/Mcb.01212-10 |
0.746 |
|
| 2009 |
Kemper JK, Xiao Z, Ponugoti B, Miao J, Fang S, Kanamaluru D, Tsang S, Wu SY, Chiang CM, Veenstra TD. FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states. Cell Metabolism. 10: 392-404. PMID 19883617 DOI: 10.1016/J.Cmet.2009.09.009 |
0.663 |
|
| 2009 |
Miao J, Fang S, Lee J, Comstock C, Knudsen KE, Kemper JK. Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis. Molecular and Cellular Biology. 29: 6170-81. PMID 19805516 DOI: 10.1128/Mcb.00825-09 |
0.799 |
|
| 2008 |
Fang S, Tsang S, Jones R, Ponugoti B, Yoon H, Wu SY, Chiang CM, Willson TM, Kemper JK. The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP. The Journal of Biological Chemistry. 283: 35086-95. PMID 18842595 DOI: 10.1074/Jbc.M803531200 |
0.793 |
|
| 2007 |
Ponugoti B, Fang S, Kemper JK. Functional interaction of hepatic nuclear factor-4 and peroxisome proliferator-activated receptor-gamma coactivator 1alpha in CYP7A1 regulation is inhibited by a key lipogenic activator, sterol regulatory element-binding protein-1c. Molecular Endocrinology (Baltimore, Md.). 21: 2698-712. PMID 17636037 DOI: 10.1210/Me.2007-0196 |
0.747 |
|
| 2007 |
Fang S, Miao J, Xiang L, Ponugoti B, Treuter E, Kemper JK. Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism. Molecular and Cellular Biology. 27: 1407-24. PMID 17145766 DOI: 10.1128/Mcb.00944-06 |
0.745 |
|
| 2006 |
Miao J, Fang S, Bae Y, Kemper JK. Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha. The Journal of Biological Chemistry. 281: 14537-46. PMID 16492670 DOI: 10.1074/Jbc.M510713200 |
0.798 |
|
| 2004 |
Bhalla S, Ozalp C, Fang S, Xiang L, Kemper JK. Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism. The Journal of Biological Chemistry. 279: 45139-47. PMID 15322103 DOI: 10.1074/Jbc.M405423200 |
0.776 |
|
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