Scott A. Gerber, Ph.D. - Publications

Affiliations: 
2001 University of Washington, Seattle, Seattle, WA 
Area:
Analytical Chemistry, Genetics, Organic Chemistry

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Brauer BL, Wiredu K, Mitchell S, Moorhead GB, Gerber SA, Kettenbach AN. Affinity-based profiling of endogenous phosphoprotein phosphatases by mass spectrometry. Nature Protocols. PMID 34518704 DOI: 10.1038/s41596-021-00604-3  0.305
2020 Gerbich TM, McLaughlin GA, Cassidy K, Gerber S, Adalsteinsson D, Gladfelter AS. Phosphoregulation provides specificity to biomolecular condensates in the cell cycle and cell polarity. The Journal of Cell Biology. 219. PMID 32399546 DOI: 10.1083/Jcb.201910021  0.367
2020 Park EM, Scott PM, Clutario K, Cassidy KB, Zhan K, Gerber SA, Holland AJ. WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication. The Journal of Cell Biology. 219. PMID 31874114 DOI: 10.1083/Jcb.201904203  0.308
2019 Cassidy KB, Bang S, Kurokawa M, Gerber SA. Direct regulation of Chk1 protein stability by E3 ubiquitin ligase HUWE1. The Febs Journal. PMID 31713291 DOI: 10.1111/Febs.15132  0.349
2019 Mills BN, Connolly KA, Ye J, Murphy JD, Uccello TP, Han BJ, Zhao T, Drage MG, Murthy A, Qiu H, Patel A, Figueroa NM, Johnston CJ, Prieto PA, Egilmez NK, ... ... Gerber SA, et al. Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment. Cell Reports. 29: 406-421.e5. PMID 31597100 DOI: 10.1016/J.Celrep.2019.08.095  0.303
2019 Krajewska M, Dries R, Grassetti AV, Dust S, Gao Y, Huang H, Sharma B, Day DS, Kwiatkowski N, Pomaville M, Dodd O, Chipumuro E, Zhang T, Greenleaf AL, Yuan GC, ... ... Gerber SA, et al. CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation. Nature Communications. 10: 1757. PMID 30988284 DOI: 10.1038/S41467-019-09703-Y  0.337
2018 Kettenbach AN, Schlosser KA, Lyons SP, Nasa I, Gui J, Adamo ME, Gerber SA. Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity. Science Signaling. 11. PMID 29764989 DOI: 10.1126/Scisignal.Aaq1441  0.391
2018 Zhao Y, Cushing PR, Smithson DC, Pellegrini M, Pletnev AA, Al-Ayyoubi S, Grassetti AV, Gerber SA, Guy RK, Madden DR. Cysteine modification reveals an allosteric inhibitory site on the CAL PDZ domain. Bioscience Reports. PMID 29472314 DOI: 10.1042/Bsr20180231  0.36
2017 Cullati SN, Kabeche L, Kettenbach AN, Gerber SA. A bifurcated signaling cascade of NIMA-related kinases controls distinct kinesins in anaphase. The Journal of Cell Biology. PMID 28630147 DOI: 10.1083/Jcb.201512055  0.363
2017 Grassetti AV, Hards R, Gerber SA. Offline pentafluorophenyl (PFP)-RP prefractionation as an alternative to high-pH RP for comprehensive LC-MS/MS proteomics and phosphoproteomics. Analytical and Bioanalytical Chemistry. PMID 28555341 DOI: 10.1007/S00216-017-0407-6  0.345
2016 Adamo ME, Gerber SA. Tempest: Accelerated MS/MS Database Search Software for Heterogeneous Computing Platforms. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. 55: 13.29.1-13.29.23. PMID 27603022 DOI: 10.1002/Cpbi.15  0.331
2016 Dubois EL, Gerber S, Kisselev A, Harel-Bellan A, Groisman R. UV-dependent phosphorylation of COP9/signalosome in UV-induced apoptosis. Oncology Reports. 35: 3101-5. PMID 26986008 DOI: 10.3892/Or.2016.4671  0.318
2016 Johnson ME, Grassetti AV, Taroni JN, Lyons SM, Schweppe D, Gordon JK, Spiera RF, Lafyatis R, Anderson PJ, Gerber SA, Whitfield ML. Stress granules and RNA processing bodies are novel autoantibody targets in systemic sclerosis. Arthritis Research & Therapy. 18: 27. PMID 26801089 DOI: 10.1186/S13075-016-0914-4  0.752
2016 Sullivan JM, Havrda MC, Kettenbach AN, Paolella BR, Zhang Z, Gerber SA, Israel MA. Phosphorylation regulates Id2 degradation and mediates the proliferation of neural precursor cells. Stem Cells (Dayton, Ohio). PMID 26756672 DOI: 10.1002/Stem.2291  0.398
2015 Shanley MR, Hawley D, Leung S, Zaidi NF, Dave R, Schlosser KA, Bandopadhyay R, Gerber SA, Liu M. LRRK2 Facilitates tau Phosphorylation through Strong Interaction with tau and cdk5. Biochemistry. 54: 5198-208. PMID 26268594 DOI: 10.1021/Acs.Biochem.5B00326  0.341
2015 Kettenbach AN, Deng L, Wu Y, Baldissard S, Adamo ME, Gerber SA, Moseley JB. Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1. Molecular & Cellular Proteomics : McP. 14: 1275-87. PMID 25720772 DOI: 10.1074/Mcp.M114.045245  0.401
2015 Kettenbach AN, Sano H, Keller SR, Lienhard GE, Gerber SA. SPECHT - single-stage phosphopeptide enrichment and stable-isotope chemical tagging: quantitative phosphoproteomics of insulin action in muscle. Journal of Proteomics. 114: 48-60. PMID 25463755 DOI: 10.1016/J.Jprot.2014.11.001  0.341
2015 Sullivan J, Havrda M, Paolella B, Kettenbach A, Gerber S, Israel MA. Abstract 2128: Phosphorylation of Id2 at the N-terminus modulates Id2 degradation and mediates cell cycle regulation in neural progenitor cells Cancer Research. 75: 2128-2128. DOI: 10.1158/1538-7445.Am2015-2128  0.42
2014 Deng L, Baldissard S, Kettenbach AN, Gerber SA, Moseley JB. Dueling kinases regulate cell size at division through the SAD kinase Cdr2. Current Biology : Cb. 24: 428-33. PMID 24508166 DOI: 10.1016/J.Cub.2014.01.009  0.368
2014 Majumder S, Sowden MP, Gerber SA, Thomas T, Christie CK, Mohan A, Yin G, Lord EM, Berk BC, Pang J. G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 419-26. PMID 24265417 DOI: 10.1161/Atvbaha.113.302689  0.307
2014 Sullivan J, Havrda M, Paolella B, Kettenbach A, Gerber S, Israel MA. Abstract 1402: Regulation of Id2 In the proliferation of glioma-initiating neural progenitor cells Cancer Research. 74: 1402-1402. DOI: 10.1158/1538-7445.Am2014-1402  0.423
2013 Gilmore JM, Milloy JA, Gerber SA. SILAC surrogates: rescue of quantitative information for orphan analytes in spike-in SILAC experiments. Analytical Chemistry. 85: 10812-9. PMID 24152235 DOI: 10.1021/Ac4021352  0.329
2013 Schweppe DK, Rigas JR, Gerber SA. Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. Journal of Proteomics. 91: 286-96. PMID 23911959 DOI: 10.1016/J.Jprot.2013.07.023  0.77
2013 Soundararajan M, Roos AK, Savitsky P, Filippakopoulos P, Kettenbach AN, Olsen JV, Gerber SA, Eswaran J, Knapp S, Elkins JM. Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition. Structure (London, England : 1993). 21: 986-96. PMID 23665168 DOI: 10.1016/J.Str.2013.03.012  0.382
2013 McNamara CR, Ahuja R, Osafo-Addo AD, Barrows D, Kettenbach A, Skidan I, Teng X, Cuny GD, Gerber S, Degterev A. Akt Regulates TNFα synthesis downstream of RIP1 kinase activation during necroptosis. Plos One. 8: e56576. PMID 23469174 DOI: 10.1371/Journal.Pone.0056576  0.368
2012 Christofferson DE, Li Y, Hitomi J, Zhou W, Upperman C, Zhu H, Gerber SA, Gygi S, Yuan J. A novel role for RIP1 kinase in mediating TNFa production Cell Death and Disease. 3. PMID 22695613 DOI: 10.1038/Cddis.2012.64  0.586
2012 Milloy JA, Faherty BK, Gerber SA. Tempest: GPU-CPU computing for high-throughput database spectral matching. Journal of Proteome Research. 11: 3581-91. PMID 22640374 DOI: 10.1021/Pr300338P  0.347
2012 Kettenbach AN, Wang T, Faherty BK, Madden DR, Knapp S, Bailey-Kellogg C, Gerber SA. Rapid determination of multiple linear kinase substrate motifs by mass spectrometry. Chemistry & Biology. 19: 608-18. PMID 22633412 DOI: 10.1016/J.Chembiol.2012.04.011  0.401
2012 Zhang A, Petrov KO, Hyun ER, Liu Z, Gerber SA, Myers LC. The Tlo proteins are stoichiometric components of Candida albicans mediator anchored via the Med3 subunit. Eukaryotic Cell. 11: 874-84. PMID 22562472 DOI: 10.1128/Ec.00095-12  0.323
2012 Hood EA, Kettenbach AN, Gerber SA, Compton DA. Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation. Molecular Biology of the Cell. 23: 2264-74. PMID 22535524 DOI: 10.1091/Mbc.E11-12-1013  0.337
2012 Wang T, Kettenbach AN, Gerber SA, Bailey-Kellogg C. MMFPh: a maximal motif finder for phosphoproteomics datasets. Bioinformatics (Oxford, England). 28: 1562-70. PMID 22531218 DOI: 10.1093/Bioinformatics/Bts195  0.447
2012 Gilmore JM, Kettenbach AN, Gerber SA. Increasing phosphoproteomic coverage through sequential digestion by complementary proteases. Analytical and Bioanalytical Chemistry. 402: 711-20. PMID 22002561 DOI: 10.1007/S00216-011-5466-5  0.422
2012 Hsu J, Huang H, Lee C, Yu S, Gerber S, Zon LI, Speck NA. CHD7 Negatively Regulates Hematopoietic Stem Cell Potency Blood. 120: 850-850. DOI: 10.1182/Blood.V120.21.850.850  0.329
2011 Liu M, Kang S, Ray S, Jackson J, Zaitsev AD, Gerber SA, Cuny GD, Glicksman MA. Kinetic, mechanistic, and structural modeling studies of truncated wild-type leucine-rich repeat kinase 2 and the G2019S mutant. Biochemistry. 50: 9399-408. PMID 21961647 DOI: 10.1021/Bi201173D  0.338
2011 Kettenbach AN, Gerber SA. Rapid and reproducible single-stage phosphopeptide enrichment of complex peptide mixtures: application to general and phosphotyrosine-specific phosphoproteomics experiments. Analytical Chemistry. 83: 7635-44. PMID 21899308 DOI: 10.1021/Ac201894J  0.423
2011 Yore MM, Kettenbach AN, Sporn MB, Gerber SA, Liby KT. Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR. Plos One. 6: e22862. PMID 21818401 DOI: 10.1371/Journal.Pone.0022862  0.362
2011 Kettenbach AN, Schweppe DK, Faherty BK, Pechenick D, Pletnev AA, Gerber SA. Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells. Science Signaling. 4: rs5. PMID 21712546 DOI: 10.1126/Scisignal.2001497  0.778
2011 Kettenbach AN, Rush J, Gerber SA. Absolute quantification of protein and post-translational modification abundance with stable isotope-labeled synthetic peptides. Nature Protocols. 6: 175-86. PMID 21293459 DOI: 10.1038/Nprot.2010.196  0.408
2011 Hsu J, Lee C, Gerber S, Yu S, Speck NA. Runx1-Cbfb Interacts with CHD7, a Chromatin Modifying Enzyme with a Potential Role in Hematopoiesis Blood. 118: 1300-1300. DOI: 10.1182/Blood.V118.21.1300.1300  0.3
2010 Faherty BK, Gerber SA. MacroSEQUEST: efficient candidate-centric searching and high-resolution correlation analysis for large-scale proteomics data sets. Analytical Chemistry. 82: 6821-9. PMID 20684545 DOI: 10.1021/Ac100783X  0.344
2010 Choi SH, Wright JB, Gerber SA, Cole MD. Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells. Genes & Development. 24: 1236-41. PMID 20551172 DOI: 10.1101/Gad.1920310  0.368
2010 Gerber SA, Kettenbach AN, Schweppe DK, Dragnev KH, Rigas JR. Use of quantitative proteomics to evaluate substrates and functional modules of the aurora and polo-like kinases. Journal of Clinical Oncology. 28: e13530-e13530. DOI: 10.1200/Jco.2010.28.15_Suppl.E13530  0.769
2009 Wai SC, Gerber SA, Li R. Multisite phosphorylation of the guanine nucleotide exchange factor Cdc24 during yeast cell polarization. Plos One. 4: e6563. PMID 19668330 DOI: 10.1371/Journal.Pone.0006563  0.331
2009 Baker CL, Kettenbach AN, Loros JJ, Gerber SA, Dunlap JC. Quantitative proteomics reveals a dynamic interactome and phase-specific phosphorylation in the Neurospora circadian clock. Molecular Cell. 34: 354-63. PMID 19450533 DOI: 10.1016/J.Molcel.2009.04.023  0.386
2009 Lyons PD, Peck GR, Kettenbach AN, Gerber SA, Roudaia L, Lienhard GE. Insulin stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes. Bioscience Reports. 29: 229-35. PMID 19006485 DOI: 10.1042/Bsr20080162  0.319
2008 Motamedi MR, Hong EJ, Li X, Gerber S, Denison C, Gygi S, Moazed D. HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms. Molecular Cell. 32: 778-90. PMID 19111658 DOI: 10.1016/J.Molcel.2008.10.026  0.566
2008 Bakalarski CE, Elias JE, Villén J, Haas W, Gerber SA, Everley PA, Gygi SP. The impact of peptide abundance and dynamic range on stable-isotope-based quantitative proteomic analyses. Journal of Proteome Research. 7: 4756-65. PMID 18798661 DOI: 10.1021/Pr800333E  0.699
2008 Degterev A, Hitomi J, Germscheid M, Ch'en IL, Korkina O, Teng X, Abbott D, Cuny GD, Yuan C, Wagner G, Hedrick SM, Gerber SA, Lugovskoy A, Yuan J. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nature Chemical Biology. 4: 313-21. PMID 18408713 DOI: 10.1038/Nchembio.83  0.341
2008 Loring GL, Christensen KC, Gerber SA, Brenner C. Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination. Cell Cycle (Georgetown, Tex.). 7: 96-105. PMID 18202552 DOI: 10.4161/Cc.7.1.5113  0.356
2007 Gerber SA, Kettenbach AN, Rush J, Gygi SP. The absolute quantification strategy: application to phosphorylation profiling of human separase serine 1126. Methods in Molecular Biology (Clifton, N.J.). 359: 71-86. PMID 17484111 DOI: 10.1007/978-1-59745-255-7_5  0.631
2007 Li X, Gerber SA, Rudner AD, Beausoleil SA, Haas W, Villén J, Elias JE, Gygi SP. Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae. Journal of Proteome Research. 6: 1190-7. PMID 17330950 DOI: 10.1021/Pr060559J  0.782
2007 Villén J, Beausoleil SA, Gerber SA, Gygi SP. Large-scale phosphorylation analysis of mouse liver. Proceedings of the National Academy of Sciences of the United States of America. 104: 1488-93. PMID 17242355 DOI: 10.1073/Pnas.0609836104  0.769
2006 Moazed D, Bühler M, Buker SM, Colmenares SU, Gerace EL, Gerber SA, Hong EJ, Motamedi MR, Verdel A, Villén J, Gygi SP. Studies on the mechanism of RNAi-dependent heterochromatin assembly. Cold Spring Harbor Symposia On Quantitative Biology. 71: 461-71. PMID 17381328 DOI: 10.1101/Sqb.2006.71.044  0.543
2006 Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Nature Biotechnology. 24: 1285-92. PMID 16964243 DOI: 10.1038/Nbt1240  0.772
2006 Everley PA, Bakalarski CE, Elias JE, Waghorne CG, Beausoleil SA, Gerber SA, Faherty BK, Zetter BR, Gygi SP. Enhanced analysis of metastatic prostate cancer using stable isotopes and high mass accuracy instrumentation. Journal of Proteome Research. 5: 1224-31. PMID 16674112 DOI: 10.1021/Pr0504891  0.772
2006 Haas W, Faherty BK, Gerber SA, Elias JE, Beausoleil SA, Bakalarski CE, Li X, Villén J, Gygi SP. Optimization and use of peptide mass measurement accuracy in shotgun proteomics. Molecular & Cellular Proteomics : McP. 5: 1326-37. PMID 16635985 DOI: 10.1074/Mcp.M500339-Mcp200  0.763
2005 Dieguez-Acuna FJ, Gerber SA, Kodama S, Elias JE, Beausoleil SA, Faustman D, Gygi SP. Characterization of mouse spleen cells by subtractive proteomics. Molecular & Cellular Proteomics : McP. 4: 1459-70. PMID 16037072 DOI: 10.1074/Mcp.M500137-Mcp200  0.764
2005 Lugade AA, Moran JP, Gerber SA, Rose RC, Frelinger JG, Lord EM. Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. Journal of Immunology (Baltimore, Md. : 1950). 174: 7516-23. PMID 15944250 DOI: 10.4049/Jimmunol.174.12.7516  0.305
2005 Kirkpatrick DS, Gerber SA, Gygi SP. The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications. Methods (San Diego, Calif.). 35: 265-73. PMID 15722223 DOI: 10.1016/J.Ymeth.2004.08.018  0.611
2005 Ballif BA, Roux PP, Gerber SA, MacKeigan JP, Blenis J, Gygi SP. Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors. Proceedings of the National Academy of Sciences of the United States of America. 102: 667-72. PMID 15647351 DOI: 10.1073/Pnas.0409143102  0.633
2005 Denison C, Rudner AD, Gerber SA, Bakalarski CE, Moazed D, Gygi SP. A proteomic strategy for gaining insights into protein sumoylation in yeast. Molecular & Cellular Proteomics : McP. 4: 246-54. PMID 15542864 DOI: 10.1074/Mcp.M400154-Mcp200  0.643
2004 Motamedi MR, Verdel A, Colmenares SU, Gerber SA, Gygi SP, Moazed D. Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Cell. 119: 789-802. PMID 15607976 DOI: 10.1016/J.Cell.2004.11.034  0.527
2004 Tanny JC, Kirkpatrick DS, Gerber SA, Gygi SP, Moazed D. Budding yeast silencing complexes and regulation of Sir2 activity by protein-protein interactions. Molecular and Cellular Biology. 24: 6931-46. PMID 15282295 DOI: 10.1128/Mcb.24.16.6931-6946.2004  0.577
2004 Verdel A, Jia S, Gerber S, Sugiyama T, Gygi S, Grewal SI, Moazed D. RNAi-mediated targeting of heterochromatin by the RITS complex. Science (New York, N.Y.). 303: 672-6. PMID 14704433 DOI: 10.1126/Science.1093686  0.551
2004 Vrabioiu AM, Gerber SA, Gygi SP, Field CM, Mitchison TJ. The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides. The Journal of Biological Chemistry. 279: 3111-8. PMID 14597621 DOI: 10.1074/Jbc.M310941200  0.57
2003 Gerber SA, Rush J, Stemman O, Kirschner MW, Gygi SP. Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS. Proceedings of the National Academy of Sciences of the United States of America. 100: 6940-5. PMID 12771378 DOI: 10.1073/Pnas.0832254100  0.649
2002 Hoppe GJ, Tanny JC, Rudner AD, Gerber SA, Danaie S, Gygi SP, Moazed D. Steps in assembly of silent chromatin in yeast: Sir3-independent binding of a Sir2/Sir4 complex to silencers and role for Sir2-dependent deacetylation. Molecular and Cellular Biology. 22: 4167-80. PMID 12024030 DOI: 10.1128/Mcb.22.12.4167-4180.2002  0.546
2001 Stemmann O, Zou H, Gerber SA, Gygi SP, Kirschner MW. Dual inhibition of sister chromatid separation at metaphase. Cell. 107: 715-26. PMID 11747808 DOI: 10.1016/S0092-8674(01)00603-1  0.532
2001 Gerber SA, Tureček F, Gelb MH. Design and synthesis of substrate and internal standard conjugates for profiling enzyme activity in the sanfilippo syndrome by affinity chromatography/electrospray ionization mass spectrometry Bioconjugate Chemistry. 12: 603-615. PMID 11459466 DOI: 10.1021/Bc010007L  0.469
2001 Gerber SA, Scott CR, Turecek F, Gelb MH. Direct profiling of multiple enzyme activities in human cell lysates by affinity chromatography/electrospray ionization mass spectrometry: application to clinical enzymology. Analytical Chemistry. 73: 1651-7. PMID 11338575 DOI: 10.1021/ac0100650  0.446
1999 Gygi SP, Rist B, Gerber SA, Turecek F, Gelb MH, Aebersold R. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nature Biotechnology. 17: 994-9. PMID 10504701 DOI: 10.1038/13690  0.705
1999 Gerber SA, Scott CR, Turecek F, Gelb MH. Analysis of Rates of Multiple Enzymes in Cell Lysates by Electrospray Ionization Mass SpectrometryJ. Am. Chem. Soc.1999,121, 1102−1103 Journal of the American Chemical Society. 121: 1762-1762. DOI: 10.1021/Ja995502V  0.501
1999 Gerber SA, Scott CR, Turecek F, Gelb MH. Analysis of rates of multiple enzymes in cell lysates by electrospray ionization mass spectrometry [8] Journal of the American Chemical Society. 121: 1102-1103. DOI: 10.1021/Ja982878K  0.501
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