| Year |
Citation |
Score |
| 2019 |
Oertell K, Florian J, Haratipour P, Crans DC, Kashemirov BA, Wilson SH, McKenna CE, Goodman MF. A Transition-State Perspective on Y-Family DNA Polymerase η Fidelity in Comparison with X-Family DNA Polymerases λ and β. Biochemistry. PMID 30839203 DOI: 10.1021/Acs.Biochem.9B00087 |
0.638 |
|
| 2018 |
Oertell K, Kashemirov BA, Negahbani A, Minard C, Haratipour P, Alnajjar KS, Sweasy JB, Batra VK, Beard WA, Wilson SH, McKenna CE, Goodman MF. Probing DNA base-dependent leaving group kinetic effects on the DNA polymerase transition state. Biochemistry. PMID 29889506 DOI: 10.1021/Acs.Biochem.8B00417 |
0.687 |
|
| 2018 |
Batra VK, Oertell K, Beard WA, Kashemirov BA, McKenna CE, Goodman MF, Wilson SH. Mapping functional substrate-enzyme interactions in the pol β active site through chemical biology: Structural responses to acidity modification of incoming dNTPs. Biochemistry. PMID 29874056 DOI: 10.1021/Acs.Biochem.8B00418 |
0.625 |
|
| 2016 |
Oertell K, Harcourt EM, Mohsen MG, Petruska J, Kool ET, Goodman MF. Kinetic selection vs. free energy of DNA base pairing in control of polymerase fidelity. Proceedings of the National Academy of Sciences of the United States of America. PMID 27044101 DOI: 10.1073/Pnas.1600279113 |
0.66 |
|
| 2015 |
Kadina AP, Kashemirov BA, Oertell K, Batra VK, Wilson SH, Goodman MF, McKenna CE. Two Scaffolds from Two Flips: (α,β)/(β,γ) CH2/NH "Met-Im" Analogues of dTTP. Organic Letters. 17: 2586-9. PMID 25970636 DOI: 10.1021/Acs.Orglett.5B00799 |
0.473 |
|
| 2014 |
Shakhmin A, Jones JP, Bychinskaya I, Zibinsky M, Oertell K, Goodman MF, Prakash GK. Preparation of fluorinated RNA nucleotide analogs potentially stable to enzymatic hydrolysis in RNA and DNA polymerase assays. Journal of Fluorine Chemistry. 167: 226-230. PMID 26279588 DOI: 10.1016/J.Jfluchem.2014.07.019 |
0.566 |
|
| 2014 |
Oertell K, Chamberlain BT, Wu Y, Ferri E, Kashemirov BA, Beard WA, Wilson SH, McKenna CE, Goodman MF. Transition state in DNA polymerase β catalysis: rate-limiting chemistry altered by base-pair configuration. Biochemistry. 53: 1842-8. PMID 24580380 DOI: 10.1021/Bi500101Z |
0.686 |
|
| 2014 |
Shakhmin A, Jones JP, Bychinskaya I, Zibinsky M, Oertell K, Goodman MF, Prakash GKS. Preparation of fluorinated RNA nucleotide analogs potentially stable to enzymatic hydrolysis in RNA and DNA polymerase assays Journal of Fluorine Chemistry. DOI: 10.1016/j.jfluchem.2014.07.019 |
0.491 |
|
| 2012 |
Oertell K, Wu Y, Zakharova VM, Kashemirov BA, Shock DD, Beard WA, Wilson SH, McKenna CE, Goodman MF. Effect of β,γ-CHF- and β,γ-CHCl-dGTP halogen atom stereochemistry on the transition state of DNA polymerase β. Biochemistry. 51: 8491-501. PMID 23043620 DOI: 10.1021/Bi3010335 |
0.54 |
|
| 2010 |
Surya Prakash GK, Zibinsky M, Upton TG, Kashemirov BA, McKenna CE, Oertell K, Goodman MF, Batra VK, Pedersen LC, Beard WA, Shock DD, Wilson SH, Olah GA. Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. Proceedings of the National Academy of Sciences of the United States of America. 107: 15693-8. PMID 20724659 DOI: 10.1073/Pnas.1007430107 |
0.612 |
|
| 2010 |
Bertram JG, Oertell K, Petruska J, Goodman MF. DNA polymerase fidelity: comparing direct competition of right and wrong dNTP substrates with steady state and pre-steady state kinetics. Biochemistry. 49: 20-8. PMID 20000359 DOI: 10.1021/Bi901653G |
0.613 |
|
| 2008 |
Sucato CA, Upton TG, Kashemirov BA, Osuna J, Oertell K, Beard WA, Wilson SH, Florián J, Warshel A, McKenna CE, Goodman MF. DNA polymerase beta fidelity: halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state. Biochemistry. 47: 870-9. PMID 18161950 DOI: 10.1021/Bi7014162 |
0.511 |
|
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