| Year |
Citation |
Score |
| 2023 |
Jimenez-Harrison D, Huseby CJ, Hoffman CN, Sher S, Snyder D, Seal B, Yuan C, Fu H, Wysocki V, Giorgini F, Kuret J. DJ-1 Molecular Chaperone Activity Depresses Tau Aggregation Propensity through Interaction with Monomers. Biochemistry. 62: 976-988. PMID 36813261 DOI: 10.1021/acs.biochem.2c00581 |
0.367 |
|
| 2022 |
Santiago-Mujika E, Luthi-Carter R, Giorgini F, Mukaetova-Ladinska EB. Tubulin Isotypes and Posttranslational Modifications in Vascular Dementia and Alzheimer's Disease. Journal of Alzheimer's Disease Reports. 6: 739-748. PMID 36606207 DOI: 10.3233/ADR-220068 |
0.675 |
|
| 2022 |
Jordan KL, Koss DJ, Outeiro TF, Giorgini F. Therapeutic Targeting of Rab GTPases: Relevance for Alzheimer's Disease. Biomedicines. 10. PMID 35625878 DOI: 10.3390/biomedicines10051141 |
0.357 |
|
| 2021 |
Santiago-Mujika E, Luthi-Carter R, Giorgini F, Kalaria RN, Mukaetova-Ladinska EB. Tubulin and Tubulin Posttranslational Modifications in Alzheimer's Disease and Vascular Dementia. Frontiers in Aging Neuroscience. 13: 730107. PMID 34776926 DOI: 10.3389/fnagi.2021.730107 |
0.676 |
|
| 2021 |
Pruccoli L, Breda C, Teti G, Falconi M, Giorgini F, Tarozzi A. Esculetin Provides Neuroprotection against Mutant Huntingtin-Induced Toxicity in Huntington's Disease Models. Pharmaceuticals (Basel, Switzerland). 14. PMID 34681268 DOI: 10.3390/ph14101044 |
0.313 |
|
| 2021 |
Koss DJ, Campesan S, Giorgini F, Outeiro TF. Dysfunction of RAB39B-Mediated Vesicular Trafficking in Lewy Body Diseases. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33939203 DOI: 10.1002/mds.28605 |
0.338 |
|
| 2020 |
Delfino L, Mason RP, Kyriacou CP, Giorgini F, Rosato E. Rab8 Promotes Mutant HTT Aggregation, Reduces Neurodegeneration, and Ameliorates Behavioural Alterations in a Drosophila Model of Huntington's Disease. Journal of Huntington's Disease. 9: 253-263. PMID 33044189 DOI: 10.3233/JHD-200411 |
0.326 |
|
| 2020 |
Koss DJ, Bondarevaite O, Adams S, Leite M, Giorgini F, Attems J, Outeiro TF. RAB39B is redistributed in dementia with lewy bodies and is sequestered within Aβ plaques and lewy bodies. Brain Pathology (Zurich, Switzerland). PMID 32762091 DOI: 10.1111/Bpa.12890 |
0.462 |
|
| 2020 |
Aron R, Pellegrini P, Green EW, Maddison DC, Opoku-Nsiah K, Osorio Oliviera A, Wong JS, Daub AC, Giorgini F, Muchowski P, Finkbeiner S. Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease. Nature Communications. 11: 1065. PMID 32081961 DOI: 10.1038/S41467-020-14582-9 |
0.325 |
|
| 2019 |
Spiers JG, Breda C, Robinson S, Giorgini F, Steinert JR. Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity. Frontiers in Molecular Neuroscience. 12: 86. PMID 31040766 DOI: 10.3389/Fnmol.2019.00086 |
0.343 |
|
| 2018 |
Aron R, Pellegrini P, Green EW, Maddison DC, Opoku-Nsiah K, Wong JS, Daub AC, Giorgini F, Finkbeiner S. Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease. Nature Communications. 9: 3191. PMID 30266909 DOI: 10.1038/S41467-018-05653-Z |
0.44 |
|
| 2018 |
Sathyasaikumar KV, Breda C, Schwarcz R, Giorgini F. Assessing and Modulating Kynurenine Pathway Dynamics in Huntington's Disease: Focus on Kynurenine 3-Monooxygenase. Methods in Molecular Biology (Clifton, N.J.). 1780: 397-413. PMID 29856028 DOI: 10.1007/978-1-4939-7825-0_18 |
0.34 |
|
| 2018 |
Repici M, Hassanjani M, Maddison DC, Garção P, Cimini S, Patel B, Szegö ÉM, Straatman KR, Lilley KS, Borsello T, Outeiro TF, Panman L, Giorgini F. The Parkinson's Disease-Linked Protein DJ-1 Associates with Cytoplasmic mRNP Granules During Stress and Neurodegeneration. Molecular Neurobiology. PMID 29675578 DOI: 10.1007/S12035-018-1084-Y |
0.347 |
|
| 2018 |
Robinson SW, Bourgognon JM, Spiers JG, Breda C, Campesan S, Butcher A, Mallucci GR, Dinsdale D, Morone N, Mistry R, Smith TM, Guerra-Martin M, Challiss RAJ, Giorgini F, Steinert JR. Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability. Plos Biology. 16: e2003611. PMID 29630591 DOI: 10.1371/Journal.Pbio.2003611 |
0.371 |
|
| 2018 |
Breda C, Swaih AM, Repici M, Giorgini F. A29 Kynurenine 3-monooxygenase interacts with huntingtin at the outer mitochondrial membrane Journal of Neurology, Neurosurgery, and Psychiatry. 89. DOI: 10.1136/Jnnp-2018-Ehdn.27 |
0.332 |
|
| 2018 |
Naia L, Carmo C, Campesan S, Lopes C, Valero J, Rosenstock TR, Giorgini F, Cristina Rego A. SIRT 3 , a modifier of mitochondrial function in Huntington's disease Free Radical Biology and Medicine. 120: S17. DOI: 10.1016/J.Freeradbiomed.2018.04.072 |
0.327 |
|
| 2017 |
Branco-Santos J, Herrera F, Poças GM, Pires-Afonso Y, Giorgini F, Domingos PM, Outeiro TF. Protein phosphatase 1 regulates huntingtin exon 1 aggregation and toxicity. Human Molecular Genetics. 26: 3763-3775. PMID 28934390 DOI: 10.1093/Hmg/Ddx260 |
0.41 |
|
| 2017 |
Vicente Miranda H, Szego ÉM, Oliveira LM, Breda C, Darendelioglu E, de Oliveira RM, Ferreira DG, Gomes MA, Rott R, Oliveira M, Munari F, Enguita FJ, Simões T, Rodrigues EF, Heinrich M, ... ... Giorgini F, et al. Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies. Brain : a Journal of Neurology. PMID 28398476 DOI: 10.1093/Brain/Awx056 |
0.364 |
|
| 2016 |
Vicente Miranda H, Gomes MA, Branco-Santos J, Breda C, Lázaro DF, Lopes LV, Herrera F, Giorgini F, Outeiro TF. Glycation potentiates neurodegeneration in models of Huntington's disease. Scientific Reports. 6: 36798. PMID 27857176 DOI: 10.1038/Srep36798 |
0.48 |
|
| 2016 |
Gonçalves SA, Macedo D, Raquel H, Simões PD, Giorgini F, Ramalho JS, Barral DC, Ferreira Moita L, Outeiro TF. shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity. Plos Genetics. 12: e1005995. PMID 27123591 DOI: 10.1371/Journal.Pgen.1005995 |
0.405 |
|
| 2016 |
Breda C, Sathyasaikumar KV, Sograte Idrissi S, Notarangelo FM, Estranero JG, Moore GG, Green EW, Kyriacou CP, Schwarcz R, Giorgini F. Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114543 DOI: 10.1136/Jnnp-2016-314597.273 |
0.398 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Giorgini F, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.301 |
|
| 2016 |
Smalley JL, Breda C, Mason RP, Kooner G, Luthi-Carter R, Gant TW, Giorgini F. Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington's disease models. Journal of Molecular Medicine (Berlin, Germany). 94: 235-45. PMID 26428929 DOI: 10.1007/S00109-015-1344-5 |
0.664 |
|
| 2016 |
Giorgini F. A3 Exploring mitochondrial dysfunction and dynamics in HD Journal of Neurology, Neurosurgery & Psychiatry. 87: A1.3-A1. DOI: 10.1136/Jnnp-2016-314597.3 |
0.354 |
|
| 2015 |
Maddison DC, Giorgini F. The kynurenine pathway and neurodegenerative disease. Seminars in Cell & Developmental Biology. 40: 134-41. PMID 25773161 DOI: 10.1016/J.Semcdb.2015.03.002 |
0.393 |
|
| 2015 |
Varadarajan S, Breda C, Smalley JL, Butterworth M, Farrow SN, Giorgini F, Cohen GM. The transrepression arm of glucocorticoid receptor signaling is protective in mutant huntingtin-mediated neurodegeneration. Cell Death and Differentiation. 22: 1388-96. PMID 25656655 DOI: 10.1038/Cdd.2015.1 |
0.367 |
|
| 2015 |
Breda C, Nugent ML, Estranero JG, Kyriacou CP, Outeiro TF, Steinert JR, Giorgini F. Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour. Human Molecular Genetics. 24: 1077-91. PMID 25305083 DOI: 10.1093/Hmg/Ddu521 |
0.331 |
|
| 2014 |
Chutna O, Gonçalves S, Villar-Piqué A, Guerreiro P, Marijanovic Z, Mendes T, Ramalho J, Emmanouilidou E, Ventura S, Klucken J, Barral DC, Giorgini F, Vekrellis K, Outeiro TF. The small GTPase Rab11 co-localizes with α-synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity. Human Molecular Genetics. 23: 6732-45. PMID 25092884 DOI: 10.1093/Hmg/Ddu391 |
0.385 |
|
| 2014 |
Zondler L, Miller-Fleming L, Repici M, Gonçalves S, Tenreiro S, Rosado-Ramos R, Betzer C, Straatman KR, Jensen PH, Giorgini F, Outeiro TF. DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease. Cell Death & Disease. 5: e1350. PMID 25058424 DOI: 10.1038/Cddis.2014.307 |
0.366 |
|
| 2014 |
Yin G, Lopes da Fonseca T, Eisbach SE, Anduaga AM, Breda C, Orcellet ML, Szeg? ÉM, Guerreiro P, Lázaro DF, Braus GH, Fernandez CO, Griesinger C, Becker S, Goody RS, Itzen A, ... Giorgini F, et al. α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner. Neurobiology of Disease. 70: 149-61. PMID 24983211 DOI: 10.1016/J.Nbd.2014.06.018 |
0.405 |
|
| 2014 |
Kantcheva RB, Mason R, Giorgini F. Aggregation-prone proteins modulate huntingtin inclusion body formation in yeast. Plos Currents. 6. PMID 24804153 DOI: 10.1371/Currents.Hd.501008F3051342C9A5C0Cd0F3A5Bf3A4 |
0.39 |
|
| 2014 |
Miller-Fleming L, Antas P, Pais TF, Smalley JL, Giorgini F, Outeiro TF. Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phase. Proceedings of the National Academy of Sciences of the United States of America. 111: 7012-7. PMID 24706893 DOI: 10.1073/Pnas.1319221111 |
0.362 |
|
| 2014 |
Vittori A, Breda C, Repici M, Orth M, Roos RA, Outeiro TF, Giorgini F, Hollox EJ. Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's disease. Human Molecular Genetics. 23: 3129-37. PMID 24452335 DOI: 10.1093/Hmg/Ddu022 |
0.394 |
|
| 2014 |
Sajjad MU, Green EW, Miller-Fleming L, Hands S, Herrera F, Campesan S, Khoshnan A, Outeiro TF, Giorgini F, Wyttenbach A. DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease. Human Molecular Genetics. 23: 755-66. PMID 24070869 DOI: 10.1093/Hmg/Ddt466 |
0.463 |
|
| 2014 |
Ozkaya O, Maddison D, Delfno L, Kyriacou C, Giorgini F, Rosato E. B43 Huntington's Disease And Circadian Rhythms: What Can Flies Teach Us? Journal of Neurology, Neurosurgery & Psychiatry. 85: A24-A24. DOI: 10.1136/Jnnp-2014-309032.71 |
0.42 |
|
| 2014 |
Miranda H, Gomes M, Branco dos Santos J, Giorgini F, Outeiro T. B08 Glycation Modulates Huntingtin Aggregation And Toxicity Journal of Neurology, Neurosurgery & Psychiatry. 85: A11-A11. DOI: 10.1136/Jnnp-2014-309032.36 |
0.421 |
|
| 2014 |
Branco dos Santos J, Staniforth G, Breda C, Herrera F, Outeiro T, Tuite M, Giorgini F. B07 Aggregation-prone Proteins Exacerbate Huntingtin Toxicity In Yeast And Drosophila Journal of Neurology, Neurosurgery & Psychiatry. 85: A11-A11. DOI: 10.1136/Jnnp-2014-309032.35 |
0.411 |
|
| 2014 |
Branco dos Santos J, Herrera F, Giorgini F, Outeiro T. B06 Exploring The Role Of Phosphorylation In Huntingtin Aggregation Dynamics Journal of Neurology, Neurosurgery & Psychiatry. 85: A11-A11. DOI: 10.1136/Jnnp-2014-309032.34 |
0.419 |
|
| 2013 |
Vittori A, Orth M, Roos RA, Outeiro TF, Giorgini F, Hollox EJ. β-Defensin Genomic Copy Number Does Not Influence the Age of Onset in Huntington's Disease. Journal of Huntington's Disease. 2: 107-124. PMID 24587836 DOI: 10.3233/Jhd-130047 |
0.336 |
|
| 2013 |
Giorgini F, Steinert JR. Rab11 as a modulator of synaptic transmission. Communicative & Integrative Biology. 6: e26807. PMID 24563714 DOI: 10.4161/Cib.26807 |
0.372 |
|
| 2013 |
Woodacre A, Lone MA, Jablonowski D, Schneiter R, Giorgini F, Schaffrath R. A novel Sit4 phosphatase complex is involved in the response to ceramide stress in yeast. Oxidative Medicine and Cellular Longevity. 2013: 129645. PMID 24082981 DOI: 10.1155/2013/129645 |
0.341 |
|
| 2013 |
Giorgini F. A flexible polyglutamine hinge opens new doors for understanding huntingtin function. Proceedings of the National Academy of Sciences of the United States of America. 110: 14516-7. PMID 23975930 DOI: 10.1073/Pnas.1313668110 |
0.431 |
|
| 2013 |
Mason RP, Casu M, Butler N, Breda C, Campesan S, Clapp J, Green EW, Dhulkhed D, Kyriacou CP, Giorgini F. Glutathione peroxidase activity is neuroprotective in models of Huntington's disease. Nature Genetics. 45: 1249-54. PMID 23974869 DOI: 10.1038/Ng.2732 |
0.427 |
|
| 2013 |
Giorgini F. Understanding neuronal dysfunction and loss in neurodegenerative disease. Journal of Molecular Medicine (Berlin, Germany). 91: 651-2. PMID 23674065 DOI: 10.1007/S00109-013-1053-X |
0.457 |
|
| 2013 |
Amaral M, Outeiro TF, Scrutton NS, Giorgini F. The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease. Journal of Molecular Medicine (Berlin, Germany). 91: 705-13. PMID 23636512 DOI: 10.1007/S00109-013-1046-9 |
0.355 |
|
| 2013 |
Amaral M, Levy C, Heyes DJ, Lafite P, Outeiro TF, Giorgini F, Leys D, Scrutton NS. Structural basis of kynurenine 3-monooxygenase inhibition. Nature. 496: 382-5. PMID 23575632 DOI: 10.1038/Nature12039 |
0.422 |
|
| 2013 |
Uthman S, Bär C, Scheidt V, Liu S, ten Have S, Giorgini F, Stark MJ, Schaffrath R. The amidation step of diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network. Plos Genetics. 9: e1003334. PMID 23468660 DOI: 10.1371/Journal.Pgen.1003334 |
0.33 |
|
| 2013 |
Repici M, Straatman KR, Balduccio N, Enguita FJ, Outeiro TF, Giorgini F. Parkinson's disease-associated mutations in DJ-1 modulate its dimerization in living cells. Journal of Molecular Medicine (Berlin, Germany). 91: 599-611. PMID 23183826 DOI: 10.1007/S00109-012-0976-Y |
0.333 |
|
| 2012 |
Kwan W, Träger U, Davalos D, Chou A, Bouchard J, Andre R, Miller A, Weiss A, Giorgini F, Cheah C, Möller T, Stella N, Akassoglou K, Tabrizi SJ, Muchowski PJ. Mutant huntingtin impairs immune cell migration in Huntington disease. The Journal of Clinical Investigation. 122: 4737-47. PMID 23160193 DOI: 10.1172/Jci64484 |
0.354 |
|
| 2012 |
Green EW, Giorgini F. Choosing and using Drosophila models to characterize modifiers of Huntington's disease. Biochemical Society Transactions. 40: 739-45. PMID 22817726 DOI: 10.1042/Bst20120072 |
0.412 |
|
| 2012 |
Green EW, Campesan S, Breda C, Sathyasaikumar KV, Muchowski PJ, Schwarcz R, Kyriacou CP, Giorgini F. Drosophila eye color mutants as therapeutic tools for Huntington disease. Fly. 6: 117-20. PMID 22634544 DOI: 10.4161/Fly.19999 |
0.421 |
|
| 2012 |
Steinert JR, Campesan S, Richards P, Kyriacou CP, Forsythe ID, Giorgini F. Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease. Human Molecular Genetics. 21: 2912-22. PMID 22466800 DOI: 10.1093/Hmg/Dds117 |
0.378 |
|
| 2011 |
Giorgini F. Is modulating translation a therapeutic option for Huntington's disease? Neurodegenerative Disease Management. 1: 89-91. PMID 24527061 DOI: 10.2217/Nmt.11.12 |
0.376 |
|
| 2011 |
Mason RP, Giorgini F. Modeling Huntington disease in yeast: perspectives and future directions. Prion. 5: 269-76. PMID 22052350 DOI: 10.4161/Pri.18005 |
0.427 |
|
| 2011 |
Zwilling D, Huang SY, Sathyasaikumar KV, Notarangelo FM, Guidetti P, Wu HQ, Lee J, Truong J, Andrews-Zwilling Y, Hsieh EW, Louie JY, Wu T, Scearce-Levie K, Patrick C, Adame A, ... Giorgini F, et al. Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration. Cell. 145: 863-74. PMID 21640374 DOI: 10.1016/J.Cell.2011.05.020 |
0.409 |
|
| 2011 |
Campesan S, Green EW, Breda C, Sathyasaikumar KV, Muchowski PJ, Schwarcz R, Kyriacou CP, Giorgini F. The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease. Current Biology : Cb. 21: 961-6. PMID 21636279 DOI: 10.1016/J.Cub.2011.04.028 |
0.416 |
|
| 2011 |
Richards P, Didszun C, Campesan S, Simpson A, Horley B, Young KW, Glynn P, Cain K, Kyriacou CP, Giorgini F, Nicotera P. Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease. Cell Death and Differentiation. 18: 191-200. PMID 21217767 DOI: 10.1038/Cdd.2010.127 |
0.447 |
|
| 2011 |
Tauber E, Miller-Fleming L, Mason RP, Kwan W, Clapp J, Butler NJ, Outeiro TF, Muchowski PJ, Giorgini F. Functional gene expression profiling in yeast implicates translational dysfunction in mutant huntingtin toxicity. The Journal of Biological Chemistry. 286: 410-9. PMID 21044956 DOI: 10.1074/Jbc.M110.101527 |
0.388 |
|
| 2010 |
Thevandavakkam MA, Schwarcz R, Muchowski PJ, Giorgini F. Targeting kynurenine 3-monooxygenase (KMO): implications for therapy in Huntington's disease. Cns & Neurological Disorders Drug Targets. 9: 791-800. PMID 20942784 DOI: 10.2174/187152710793237430 |
0.434 |
|
| 2010 |
Hands SL, Mason R, Sajjad MU, Giorgini F, Wyttenbach A. Metallothioneins and copper metabolism are candidate therapeutic targets in Huntington's disease. Biochemical Society Transactions. 38: 552-8. PMID 20298220 DOI: 10.1042/Bst0380552 |
0.375 |
|
| 2010 |
Thevandavakkam M, Fleming LM, Mason R, Fleming Outeiro T, Giorgini F. B07 Identification of protein interaction partners for kynurenine 3-monooxygenase, a candidate therapeutic target for Huntington's disease Journal of Neurology, Neurosurgery & Psychiatry. 81: A13.2-A13. DOI: 10.1136/Jnnp.2010.222596.7 |
0.398 |
|
| 2010 |
Campesan S, Green EW, Sathyasaikumar KV, Breda C, Muchowski PJ, Schwarcz R, Kyriacou CP, Giorgini F. B06 Validation of KMO as a candidate therapeutic target for Huntington's disease in Drosophila melanogaster Journal of Neurology, Neurosurgery & Psychiatry. 81: A12.3-A13. DOI: 10.1136/Jnnp.2010.222596.6 |
0.394 |
|
| 2010 |
Mason R, Fearnley N, Bishop C, Möller T, Giorgini F. B03 Identification and characterisation of overexpression suppressors of mutant huntingtin toxicity Journal of Neurology, Neurosurgery & Psychiatry. 81: A11.4-A12. DOI: 10.1136/Jnnp.2010.222596.3 |
0.366 |
|
| 2010 |
Casu M, Campesan S, Clapp J, Kyriacou CP, Giorgini F. B02 Validation of suppressors of mutant huntingtin toxicity in a fly model of Huntington's disease Journal of Neurology, Neurosurgery & Psychiatry. 81: A11.3-A11. DOI: 10.1136/Jnnp.2010.222596.2 |
0.422 |
|
| 2010 |
Vittori A, Giorgini F, Outeiro FT, Hollox EJ. C11 Copy number variation in Huntington's disease Journal of Neurology, Neurosurgery & Psychiatry. 81: A19.2-A19. DOI: 10.1136/Jnnp.2010.222588.11 |
0.353 |
|
| 2010 |
Wyttenbach A, Hands S, Mason R, Sajjad MU, Giorgini F. A08 Metallothioneins and copper metabolism: candidate therapeutic targets in Huntington's disease Journal of Neurology, Neurosurgery & Psychiatry. 81: A3.2-A3. DOI: 10.1136/Jnnp.2010.222570.8 |
0.328 |
|
| 2009 |
Wacker JL, Huang SY, Steele AD, Aron R, Lotz GP, Nguyen Q, Giorgini F, Roberson ED, Lindquist S, Masliah E, Muchowski PJ. Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9104-14. PMID 19605647 DOI: 10.1523/Jneurosci.2250-09.2009 |
0.428 |
|
| 2008 |
Miller-Fleming L, Giorgini F, Outeiro TF. Yeast as a model for studying human neurodegenerative disorders. Biotechnology Journal. 3: 325-38. PMID 18228539 DOI: 10.1002/Biot.200700217 |
0.43 |
|
| 2008 |
Giorgini F, Möller T, Kwan W, Zwilling D, Wacker JL, Hong S, Tsai LC, Cheah CS, Schwarcz R, Guidetti P, Muchowski PJ. Histone deacetylase inhibition modulates kynurenine pathway activation in yeast, microglia, and mice expressing a mutant huntingtin fragment. The Journal of Biological Chemistry. 283: 7390-400. PMID 18079112 DOI: 10.1074/Jbc.M708192200 |
0.408 |
|
| 2006 |
Giorgini F, Muchowski PJ. Screening for genetic modifiers of amyloid toxicity in yeast. Methods in Enzymology. 412: 201-22. PMID 17046660 DOI: 10.1016/S0076-6879(06)12013-3 |
0.378 |
|
| 2006 |
Outeiro TF, Giorgini F. Yeast as a drug discovery platform in Huntington's and Parkinson's diseases. Biotechnology Journal. 1: 258-69. PMID 16897706 DOI: 10.1002/Biot.200500043 |
0.469 |
|
| 2006 |
Duennwald ML, Jagadish S, Giorgini F, Muchowski PJ, Lindquist S. A network of protein interactions determines polyglutamine toxicity. Proceedings of the National Academy of Sciences of the United States of America. 103: 11051-6. PMID 16832049 DOI: 10.1073/Pnas.0604548103 |
0.387 |
|
| 2005 |
Giorgini F, Guidetti P, Nguyen Q, Bennett SC, Muchowski PJ. A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease. Nature Genetics. 37: 526-31. PMID 15806102 DOI: 10.1038/Ng1542 |
0.424 |
|
| 2005 |
Giorgini F, Muchowski PJ. Connecting the dots in Huntington's disease with protein interaction networks. Genome Biology. 6: 210. PMID 15774033 DOI: 10.1186/Gb-2005-6-3-210 |
0.405 |
|
| 2002 |
Giorgini F, Davies HG, Braun RE. Translational repression by MSY4 inhibits spermatid differentiation in mice. Development (Cambridge, England). 129: 3669-79. PMID 12117816 |
0.657 |
|
| 2001 |
Giorgini F, Davies HG, Braun RE. MSY2 and MSY4 bind a conserved sequence in the 3' untranslated region of protamine 1 mRNA in vitro and in vivo. Molecular and Cellular Biology. 21: 7010-9. PMID 11564883 DOI: 10.1128/Mcb.21.20.7010-7019.2001 |
0.672 |
|
| 2000 |
Davies HG, Giorgini F, Fajardo MA, Braun RE. A sequence-specific RNA binding complex expressed in murine germ cells contains MSY2 and MSY4. Developmental Biology. 221: 87-100. PMID 10772793 DOI: 10.1006/Dbio.2000.9658 |
0.683 |
|
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