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Laura M. Saba, Ph.D. - Publications

Affiliations: 
2007 University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Biostatistics Biology
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Saba LM, Hoffman PL, Homanics GE, Mahaffey S, Daulatabad SV, Janga SC, Tabakoff B. A Long Non-Coding RNA (Lrap) Modulates Brain Gene Expression and Levels of Alcohol Consumption in Rats. Genes, Brain, and Behavior. PMID 32893479 DOI: 10.1111/Gbb.12698  0.372
2020 Neuman MG, Seitz HK, French SW, Malnick S, Tsukamoto H, Cohen LB, Hoffman P, Tabakoff B, Fasullo M, Nagy LE, Tuma PL, Schnabl B, Mueller S, Groebner JL, Barbara FA, ... ... Saba L, et al. Alcoholic-Hepatitis, Links to Brain and Microbiome: Mechanisms, Clinical and Experimental Research. Biomedicines. 8. PMID 32197424 DOI: 10.3390/Biomedicines8030063  0.335
2019 Assiri MA, Ali HR, Marentette JO, Yun Y, Liu J, Hirschey MD, Saba LM, Harris PS, Fritz KS. Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease. Human Genomics. 13: 65. PMID 31823815 DOI: 10.1186/S40246-019-0251-1  0.33
2019 Shearn CT, Fennimore B, Orlicky DJ, Gao YR, Saba LM, Battista KD, Aivazidis S, Assiri M, Harris PS, Michel C, Merrill GF, Schmidt EE, Colgan SP, Petersen DR. Cholestatic liver disease results increased production of reactive aldehydes and an atypical periportal hepatic antioxidant response. Free Radical Biology & Medicine. PMID 31377417 DOI: 10.1016/J.Freeradbiomed.2019.07.036  0.301
2019 Tabakoff B, Smith H, Vanderlinden LA, Hoffman PL, Saba LM. Networking in Biology: The Hybrid Rat Diversity Panel. Methods in Molecular Biology (Clifton, N.J.). 2018: 213-231. PMID 31228159 DOI: 10.1007/978-1-4939-9581-3_10  0.304
2019 Ali HR, Assiri MA, Harris PS, Michel CR, Yun Y, Marentette JO, Huynh FK, Orlicky DJ, Shearn CT, Saba LM, Reisdorph R, Reisdorph N, Hirschey MD, Fritz KS. Quantifying competition among mitochondrial protein acylation events induced by ethanol metabolism. Journal of Proteome Research. PMID 30644754 DOI: 10.1021/Acs.Jproteome.8B00800  0.327
2018 Rudra P, Shi WJ, Russell P, Vestal B, Tabakoff B, Hoffman P, Kechris K, Saba L. Predictive modeling of miRNA-mediated predisposition to alcohol-related phenotypes in mouse. Bmc Genomics. 19: 639. PMID 30157779 DOI: 10.1186/S12864-018-5004-3  0.33
2018 Petersen DR, Saba LM, Sayin VI, Papagiannakopoulos T, Schmidt EE, Merrill GF, Orlicky DJ, Shearn CT. Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice. Plos One. 13: e0198139. PMID 29799837 DOI: 10.1371/Journal.Pone.0198139  0.304
2018 Lusk R, Saba LM, Vanderlinden LA, Zidek V, Silhavy J, Pravenec M, Hoffman PL, Tabakoff B. Unsupervised, statistically-based systems biology approach for unraveling the genetics of complex traits: A demonstration with ethanol metabolism. Alcoholism, Clinical and Experimental Research. PMID 29689131 DOI: 10.1111/Acer.13763  0.339
2018 Johnson M, Alsaleh N, Mendoza RP, Persaud I, Bauer AK, Saba L, Brown JM. Genomic and transcriptomic comparison of allergen and silver nanoparticle-induced mast cell degranulation reveals novel non-immunoglobulin E mediated mechanisms. Plos One. 13: e0193499. PMID 29566008 DOI: 10.1371/Journal.Pone.0193499  0.309
2017 Hoffman PL, Saba LM, Vanderlinden LA, Tabakoff B. Voluntary exposure to a toxin: the genetic influence on ethanol consumption. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 29196862 DOI: 10.1007/S00335-017-9726-3  0.381
2017 Pravenec M, Saba L, Zidek V, Landa V, Mlejnek P, Silhavy J, Simakova M, Strnad H, Trnovska J, Skop V, Huttl M, Markova I, Oliyarnyk O, Malinska H, Kazdova L, et al. Systems Genetic Analysis of Brown Adipose Tissue Function. Physiological Genomics. physiolgenomics.0009. PMID 29127223 DOI: 10.1152/Physiolgenomics.00091.2017  0.316
2017 Saba L, Hoffman P, Tabakoff B. Using Baseline Transcriptional Connectomes in Rat to Identify Genetic Pathways Associated with Predisposition to Complex Traits. Methods in Molecular Biology (Clifton, N.J.). 1488: 299-317. PMID 27933531 DOI: 10.1007/978-1-4939-6427-7_14  0.318
2016 Harrall KK, Kechris KJ, Tabakoff B, Hoffman PL, Hines LM, Tsukamoto H, Pravenec M, Printz M, Saba LM. Uncovering the liver's role in immunity through RNA co-expression networks. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 27401171 DOI: 10.1007/S00335-016-9656-5  0.315
2015 Shearn CT, Fritz KS, Shearn AH, Saba LM, Mercer KE, Engi B, Galligan JJ, Zimniak P, Orlicky DJ, Ronis MJ, Petersen DR. Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice. Redox Biology. 7: 68-77. PMID 26654979 DOI: 10.1016/J.Redox.2015.11.013  0.301
2015 Shearn CT, Orlicky DJ, Saba LM, Shearn AH, Petersen DR. Increased hepatocellular protein carbonylation in human end-stage alcoholic cirrhosis. Free Radical Biology & Medicine. PMID 26518673 DOI: 10.1016/J.Freeradbiomed.2015.10.420  0.329
2015 Saba LM, Flink SC, Vanderlinden LA, Israel Y, Tampier L, Colombo G, Kiianmaa K, Bell RL, Printz MP, Flodman P, Koob G, Richardson HN, Lombardo J, Hoffman PL, Tabakoff B. The sequenced rat brain transcriptome - its use in identifying networks predisposing alcohol consumption. The Febs Journal. 282: 3556-78. PMID 26183165 DOI: 10.1111/Febs.13358  0.374
2015 Bennett B, Larson C, Richmond PA, Odell AT, Saba LM, Tabakoff B, Dowell R, Radcliffe RA. Quantitative trait locus mapping of acute functional tolerance in the LXS recombinant inbred strains. Alcoholism, Clinical and Experimental Research. 39: 611-20. PMID 25833023 DOI: 10.1111/Acer.12678  0.353
2015 Vanderlinden LA, Saba LM, Bennett B, Hoffman PL, Tabakoff B. Influence of sex on genetic regulation of "drinking in the dark" alcohol consumption. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 26: 43-56. PMID 25559016 DOI: 10.1007/S00335-014-9553-8  0.357
2014 Hoffman PL, Saba LM, Flink S, Grahame NJ, Kechris K, Tabakoff B. Genetics of gene expression characterizes response to selective breeding for alcohol preference. Genes, Brain, and Behavior. 13: 743-57. PMID 25160899 DOI: 10.1111/Gbb.12175  0.365
2014 Vanderlinden LA, Saba LM, Printz MP, Flodman P, Koob G, Richardson HN, Hoffman PL, Tabakoff B. Is the alcohol deprivation effect genetically mediated? Studies with HXB/BXH recombinant inbred rat strains. Alcoholism, Clinical and Experimental Research. 38: 2148-57. PMID 24961585 DOI: 10.1111/Acer.12471  0.338
2013 Vanderlinden LA, Saba LM, Kechris K, Miles MF, Hoffman PL, Tabakoff B. Whole brain and brain regional coexpression network interactions associated with predisposition to alcohol consumption. Plos One. 8: e68878. PMID 23894363 DOI: 10.1371/Journal.Pone.0068878  0.361
2013 Zuo L, Saba L, Wang K, Zhang X, Krystal JH, Tabakoff B, Luo X. Exome-wide association study of replicable nonsynonymous variants conferring risk for alcohol dependence. Journal of Studies On Alcohol and Drugs. 74: 622-5. PMID 23739027 DOI: 10.15288/Jsad.2013.74.622  0.348
2013 Procopio DO, Saba LM, Walter H, Lesch O, Skala K, Schlaff G, Vanderlinden L, Clapp P, Hoffman PL, Tabakoff B. Genetic markers of comorbid depression and alcoholism in women. Alcoholism, Clinical and Experimental Research. 37: 896-904. PMID 23278386 DOI: 10.1111/Acer.12060  0.319
2012 Snell LD, Ramchandani VA, Saba L, Herion D, Heilig M, George DT, Pridzun L, Helander A, Schwandt ML, Phillips MJ, Hoffman PL, Tabakoff B. The biometric measurement of alcohol consumption. Alcoholism, Clinical and Experimental Research. 36: 332-41. PMID 21895709 DOI: 10.1111/J.1530-0277.2011.01605.X  0.324
2011 Saba LM, Bennett B, Hoffman PL, Barcomb K, Ishii T, Kechris K, Tabakoff B. A systems genetic analysis of alcohol drinking by mice, rats and men: influence of brain GABAergic transmission. Neuropharmacology. 60: 1269-80. PMID 21185315 DOI: 10.1016/J.Neuropharm.2010.12.019  0.389
2011 Bennett B, Saba LM, Hornbaker CK, Kechris KJ, Hoffman P, Tabakoff B. Genetical genomic analysis of complex phenotypes using the PhenoGen website. Behavior Genetics. 41: 625-8. PMID 21184165 DOI: 10.1007/S10519-010-9427-0  0.312
2011 Hoffman PL, Bennett B, Saba LM, Bhave SV, Carosone-Link PJ, Hornbaker CK, Kechris KJ, Williams RW, Tabakoff B. Using the Phenogen website for 'in silico' analysis of morphine-induced analgesia: identifying candidate genes. Addiction Biology. 16: 393-404. PMID 21054686 DOI: 10.1111/J.1369-1600.2010.00254.X  0.307
2011 Erfurth A, Vyssoki B, Kogoj D, Bluml V, Walter H, Lesch O, Walter H, Dal Bianco A, Bluml V, Vyssoki B, Skala K, Nakamura-Palacios EM, Tabakoff B, Procopio DO, Saba LM, et al. S18 * LESCH TYPOLOGY (LAT): FROM BASIC RESEARCH TO TREATMENT * S18.1 * LESCH ALCOHOLISM TYPOLOGY AND TEMPERAMENTS: THEIR ROLE IN ETIOLOGY, COURSE AND TREATMENT Alcohol and Alcoholism. 46: i16-i17. DOI: 10.1093/Alcalc/Agr108  0.339
2011 Pronko SP, Saba L, Hoffman PL, Tabakoff B, Rose A, Etelalahti T, Eriksson CJP, Lenz B, Sperling W, Hillemacher T, Kornhuber J. S12 * YOUNG RESEARCHER SYMPOSIUM I: ALCOHOL DEPENDENCE--NEW FINDINGS FROM THE HPA AND THE HPG AXES * S12.1 * ROLE OF ADENYLYL CYCLASE TYPE 7 IN HPA AXIS ACTIVATION DURING ETHANOL INTOXICATION, ALCOHOL DEPENDENCE AND DEPRESSION Alcohol and Alcoholism. 46: i11-i12. DOI: 10.1093/Alcalc/Agr102  0.358
2009 Tabakoff B, Saba L, Printz M, Flodman P, Hodgkinson C, Goldman D, Koob G, Richardson HN, Kechris K, Bell RL, Hübner N, Heinig M, Pravenec M, Mangion J, Legault L, et al. Genetical genomic determinants of alcohol consumption in rats and humans. Bmc Biology. 7: 70. PMID 19874574 DOI: 10.1186/1741-7007-7-70  0.377
2008 Tabakoff B, Saba L, Kechris K, Hu W, Bhave SV, Finn DA, Grahame NJ, Hoffman PL. The genomic determinants of alcohol preference in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 19: 352-65. PMID 18563486 DOI: 10.1007/S00335-008-9115-Z  0.367
2008 Hu W, Saba L, Kechris K, Bhave SV, Hoffman PL, Tabakoff B. Genomic insights into acute alcohol tolerance. The Journal of Pharmacology and Experimental Therapeutics. 326: 792-800. PMID 18550690 DOI: 10.1124/Jpet.108.137521  0.373
2006 Bhave SV, Hoffman PL, Lassen N, Vasiliou V, Saba L, Deitrich RA, Tabakoff B. Gene array profiles of alcohol and aldehyde metabolizing enzymes in brains of C57BL/6 and DBA/2 mice. Alcoholism, Clinical and Experimental Research. 30: 1659-69. PMID 17010133 DOI: 10.1111/J.1530-0277.2006.00201.X  0.325
2006 Saba L, Bhave SV, Grahame N, Bice P, Lapadat R, Belknap J, Hoffman PL, Tabakoff B. Candidate genes and their regulatory elements: alcohol preference and tolerance. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 669-88. PMID 16783646 DOI: 10.1007/S00335-005-0190-0  0.358
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