Year |
Citation |
Score |
2017 |
Kim HJ, Liu YN, McCarty RM, Liu HW. Reaction Catalyzed by GenK, a Cobalamin-Dependent Radical SAM Methyltransferase in the Biosynthetic Pathway of Gentamicin, Proceeds with Retention of Configuration. Journal of the American Chemical Society. PMID 29091410 DOI: 10.1021/jacs.7b09890 |
0.317 |
|
2017 |
Bruender NA, Grell TA, Dowling DP, McCarty RM, Drennan CL, Bandarian V. 7-Carboxy-7-deazaguanine synthase - A radical S-adenosyl-L-methionine enzyme with polar tendencies. Journal of the American Chemical Society. PMID 28045519 DOI: 10.1021/Jacs.6B11381 |
0.644 |
|
2014 |
Miles ZD, Roberts SA, McCarty RM, Bandarian V. Biochemical and structural studies of 6-carboxy-5,6,7,8-tetrahydropterin synthase reveal the molecular basis of catalytic promiscuity within the tunnel-fold superfamily. The Journal of Biological Chemistry. 289: 23641-52. PMID 24990950 DOI: 10.1074/Jbc.M114.555680 |
0.654 |
|
2014 |
Nelp MT, Astashkin AV, Breci LA, McCarty RM, Bandarian V. The alpha subunit of nitrile hydratase is sufficient for catalytic activity and post-translational modification. Biochemistry. 53: 3990-4. PMID 24914472 DOI: 10.1021/Bi500260J |
0.595 |
|
2014 |
Dowling DP, Bruender NA, Young AP, McCarty RM, Bandarian V, Drennan CL. Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism. Nature Chemical Biology. 10: 106-12. PMID 24362703 DOI: 10.1038/Nchembio.1426 |
0.658 |
|
2013 |
Kim HJ, McCarty RM, Ogasawara Y, Liu YN, Mansoorabadi SO, LeVieux J, Liu HW. GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme. Journal of the American Chemical Society. 135: 8093-6. PMID 23679096 DOI: 10.1021/Ja312641F |
0.309 |
|
2013 |
McCarty RM, Krebs C, Bandarian V. Spectroscopic, steady-state kinetic, and mechanistic characterization of the radical SAM enzyme QueE, which catalyzes a complex cyclization reaction in the biosynthesis of 7-deazapurines. Biochemistry. 52: 188-98. PMID 23194065 DOI: 10.1021/Bi301156W |
0.621 |
|
2012 |
McCarty RM, Bandarian V. Biosynthesis of pyrrolopyrimidines. Bioorganic Chemistry. 43: 15-25. PMID 22382038 DOI: 10.1016/J.Bioorg.2012.01.001 |
0.585 |
|
2011 |
Jenkins JL, Krucinska J, McCarty RM, Bandarian V, Wedekind JE. Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation. The Journal of Biological Chemistry. 286: 24626-37. PMID 21592962 DOI: 10.1074/Jbc.M111.230375 |
0.593 |
|
2011 |
Miles ZD, McCarty RM, Molnar G, Bandarian V. Discovery of epoxyqueuosine (oQ) reductase reveals parallels between halorespiration and tRNA modification. Proceedings of the National Academy of Sciences of the United States of America. 108: 7368-72. PMID 21502530 DOI: 10.1073/Pnas.1018636108 |
0.632 |
|
2009 |
McCarty RM, Somogyi A, Lin G, Jacobsen NE, Bandarian V. The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of PreQ(0) from guanosine 5'-triphosphate in four steps. Biochemistry. 48: 3847-52. PMID 19354300 DOI: 10.1021/Bi900400E |
0.659 |
|
2009 |
McCarty RM, Somogyi A, Bandarian V. Escherichia coli QueD Is a 6-Carboxy-5,6,7,8-tetrahydropterin synthase Biochemistry. 48: 2301-2303. PMID 19231875 DOI: 10.1021/Bi9001437 |
0.601 |
|
2008 |
McCarty RM, Bandarian V. Deciphering deazapurine biosynthesis: pathway for pyrrolopyrimidine nucleosides toyocamycin and sangivamycin. Chemistry & Biology. 15: 790-8. PMID 18721750 DOI: 10.1016/J.Chembiol.2008.07.012 |
0.625 |
|
2007 |
Quaranta D, McCarty R, Bandarian V, Rensing C. The copper-inducible cin operon encodes an unusual methionine-rich azurin-like protein and a pre-Q0 reductase in Pseudomonas putida KT2440. Journal of Bacteriology. 189: 5361-71. PMID 17483220 DOI: 10.1128/Jb.00377-07 |
0.596 |
|
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