Wayne Lester Hubbell - Publications

Affiliations: 
Chemistry & Biochemistry University of California, Los Angeles, Los Angeles, CA 
Area:
proteins involved in visual signal transduction (rhodopsin, the G-protein transducin and arrestin) and soluble ligand-binding proteins
Website:
http://www.chemistry.ucla.edu/directory/hubbell-wayne-l

230 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhang L, Li J, Huang Y, Zhu D, Wang H. Synergetic effect of ethyl methyl carbonate and trimethyl phosphate on BF intercalation into graphite electrode. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 30811939 DOI: 10.1021/acs.langmuir.9b00262  0.44
2019 Zhao Y, Lou J, Sun M, Fu Y, Ye W, Li Y, Dai Y, Liu Y. Hb H Disease Results from Compound Heterozygosity of - - and -α in a Chinese Family. Hemoglobin. 1-4. PMID 30810399 DOI: 10.1080/03630269.2019.1575849  0.32
2019 Yang Y, Zhang X, Ye D, Laforest R, Williamson J, Liu Y, Chen H. Cavitation dose painting for focused ultrasound-induced blood-brain barrier disruption. Scientific Reports. 9: 2840. PMID 30808897 DOI: 10.1038/s41598-019-39090-9  0.32
2019 Wingler LM, Elgeti M, Hilger D, Latorraca NR, Lerch MT, Staus DP, Dror RO, Kobilka BK, Hubbell WL, Lefkowitz RJ. Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations. Cell. PMID 30639099 DOI: 10.1016/j.cell.2018.12.005  0.4
2018 Gu X, Bridges MD, Yan Y, de Waal P, Zhou XE, Suino-Powell KM, Xu HE, Hubbell WL, Melcher K. Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK). The Journal of Biological Chemistry. PMID 30206123 DOI: 10.1074/jbc.RA118.004101  0.4
2018 Stadtmueller BM, Bridges MD, Dam KM, Lerch MT, Huey-Tubman KE, Hubbell WL, Bjorkman PJ. DEER Spectroscopy Measurements Reveal Multiple Conformations of HIV-1 SOSIP Envelopes that Show Similarities with Envelopes on Native Virions. Immunity. PMID 30076100 DOI: 10.1016/j.immuni.2018.06.017  0.4
2018 Van Eps N, Altenbach C, Caro LN, Latorraca NR, Hollingsworth SA, Dror RO, Ernst OP, Hubbell WL. G- and G-coupled GPCRs show different modes of G-protein binding. Proceedings of the National Academy of Sciences of the United States of America. PMID 29463720 DOI: 10.1073/pnas.1721896115  0.52
2017 Bergdoll LA, Lerch MT, Patrick JW, Belardo K, Altenbach C, Bisignano P, Laganowsky A, Grabe M, Hubbell WL, Abramson J. Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279396 DOI: 10.1073/pnas.1715464115  0.52
2017 Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, et al. Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors. Cell. 170: 457-469.e13. PMID 28753425 DOI: 10.1016/j.cell.2017.07.002  0.4
2017 Van Eps N, Caro LN, Morizumi T, Kusnetzow AK, Szczepek M, Hofmann KP, Bayburt TH, Sligar SG, Ernst OP, Hubbell WL. Conformational equilibria of light-activated rhodopsin in nanodiscs. Proceedings of the National Academy of Sciences of the United States of America. PMID 28373559 DOI: 10.1073/pnas.1620405114  0.4
2016 Wang H, Drawert F, Steinert M, Schulz S, Laatsch H. 1-Acyl-3-0-[β-glucopyranosyl-(1"-+ 6')-β-glucopyranosyl]-glycerols and Cordycedipeptides B and C, New Metabolites from Bacillus pumilus. Natural Product Communications. 11: 1323-1328. PMID 30807035  0.4
2016 Wheatley NM, Eden KD, Ngo J, Rosinski JS, Sawaya MR, Cascio D, Collazo M, Hoveida H, Hubbell WL, Yeates TO. A PII-like protein regulated by bicarbonate: Structural and biochemical studies of the carboxysome-associated CPII protein. Journal of Molecular Biology. PMID 27464895 DOI: 10.1016/j.jmb.2016.07.015  0.32
2016 Stadtmueller BM, Yang Z, Huey-Tubman KE, Roberts-Mataric H, Hubbell WL, Bjorkman PJ. Biophysical and Biochemical Characterization of Avian Secretory Component Provides Structural Insights into the Evolution of the Polymeric Ig Receptor. Journal of Immunology (Baltimore, Md. : 1950). PMID 27412418 DOI: 10.4049/jimmunol.1600463  0.4
2016 Yang Z, Bridges MD, López CJ, Rogozhnikova OY, Trukhin DV, Brooks EK, Tormyshev V, Halpern HJ, Hubbell WL. A triarylmethyl spin label for long-range distance measurement at physiological temperatures using T1 relaxation enhancement. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 269: 50-54. PMID 27214582 DOI: 10.1016/j.jmr.2016.05.006  1
2016 Davydov DR, Yang Z, Davydova N, Halpert JR, Hubbell WL. Conformational Mobility in Cytochrome P450 3A4 Explored by Pressure-Perturbation EPR Spectroscopy. Biophysical Journal. 110: 1485-98. PMID 27074675 DOI: 10.1016/j.bpj.2016.02.026  0.32
2016 Guo R, Gaffney K, Yang Z, Kim M, Sungsuwan S, Huang X, Hubbell WL, Hong H. Steric trapping reveals a cooperativity network in the intramembrane protease GlpG. Nature Chemical Biology. PMID 26999782 DOI: 10.1038/nchembio.2048  0.32
2016 Stadtmueller BM, Huey-Tubman KE, López CJ, Yang Z, Hubbell WL, Bjorkman PJ. The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins. Elife. 5. PMID 26943617 DOI: 10.7554/eLife.10640  0.4
2015 Altenbach C, López CJ, Hideg K, Hubbell WL. Exploring Structure, Dynamics, and Topology of Nitroxide Spin-Labeled Proteins Using Continuous-Wave Electron Paramagnetic Resonance Spectroscopy. Methods in Enzymology. 564: 59-100. PMID 26477248 DOI: 10.1016/bs.mie.2015.08.006  1
2015 Lerch MT, Yang Z, Altenbach C, Hubbell WL. High-Pressure EPR and Site-Directed Spin Labeling for Mapping Molecular Flexibility in Proteins. Methods in Enzymology. 564: 29-57. PMID 26477247 DOI: 10.1016/bs.mie.2015.07.004  1
2015 Yang Z, Bridges M, Lerch MT, Altenbach C, Hubbell WL. Saturation Recovery EPR and Nitroxide Spin Labeling for Exploring Structure and Dynamics in Proteins. Methods in Enzymology. 564: 3-27. PMID 26477246 DOI: 10.1016/bs.mie.2015.07.016  1
2015 Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, ... ... Hubbell WL, et al. Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature. PMID 26200343 DOI: 10.1038/nature14656  1
2015 Dror RO, Mildorf TJ, Hilger D, Manglik A, Borhani DW, Arlow DH, Philippsen A, Villanueva N, Yang Z, Lerch MT, Hubbell WL, Kobilka BK, Sunahara RK, Shaw DE. SIGNAL TRANSDUCTION. Structural basis for nucleotide exchange in heterotrimeric G proteins. Science (New York, N.Y.). 348: 1361-5. PMID 26089515 DOI: 10.1126/science.aaa5264  1
2015 Manglik A, Kim TH, Masureel M, Altenbach C, Yang Z, Hilger D, Lerch MT, Kobilka TS, Thian FS, Hubbell WL, Prosser RS, Kobilka BK. Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling. Cell. 161: 1101-11. PMID 25981665 DOI: 10.1016/j.cell.2015.04.043  1
2015 Lerch MT, López CJ, Yang Z, Kreitman MJ, Horwitz J, Hubbell WL. Structure-relaxation mechanism for the response of T4 lysozyme cavity mutants to hydrostatic pressure. Proceedings of the National Academy of Sciences of the United States of America. 112: E2437-46. PMID 25918400 DOI: 10.1073/pnas.1506505112  1
2015 Van Eps N, Thomas CJ, Hubbell WL, Sprang SR. The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1. Proceedings of the National Academy of Sciences of the United States of America. 112: 1404-9. PMID 25605908 DOI: 10.1073/pnas.1423878112  1
2014 López CJ, Fleissner MR, Brooks EK, Hubbell WL. Stationary-phase EPR for exploring protein structure, conformation, and dynamics in spin-labeled proteins. Biochemistry. 53: 7067-75. PMID 25333901 DOI: 10.1021/bi5011128  1
2014 Yang Z, Jiménez-Osés G, López CJ, Bridges MD, Houk KN, Hubbell WL. Long-range distance measurements in proteins at physiological temperatures using saturation recovery EPR spectroscopy. Journal of the American Chemical Society. 136: 15356-65. PMID 25290172 DOI: 10.1021/ja5083206  1
2014 Dutta A, Altenbach C, Mangahas S, Yanamala N, Gardner E, Hubbell WL, Klein-Seetharaman J. Differential dynamics of extracellular and cytoplasmic domains in denatured States of rhodopsin. Biochemistry. 53: 7160-9. PMID 25268658 DOI: 10.1021/bi401557e  1
2014 Vendome J, Felsovalyi K, Song H, Yang Z, Jin X, Brasch J, Harrison OJ, Ahlsen G, Bahna F, Kaczynska A, Katsamba PS, Edmond D, Hubbell WL, Shapiro L, Honig B. Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proceedings of the National Academy of Sciences of the United States of America. 111: E4175-84. PMID 25253890 DOI: 10.1073/pnas.1416737111  1
2014 Lerch MT, Yang Z, Brooks EK, Hubbell WL. Mapping protein conformational heterogeneity under pressure with site-directed spin labeling and double electron-electron resonance. Proceedings of the National Academy of Sciences of the United States of America. 111: E1201-10. PMID 24707053 DOI: 10.1073/pnas.1403179111  1
2014 Schredelseker J, Paz A, López CJ, Altenbach C, Leung CS, Drexler MK, Chen JN, Hubbell WL, Abramson J. High resolution structure and double electron-electron resonance of the zebrafish voltage-dependent anion channel 2 reveal an oligomeric population. The Journal of Biological Chemistry. 289: 12566-77. PMID 24627492 DOI: 10.1074/jbc.M113.497438  1
2014 Chen Q, Zhuo Y, Kim M, Hanson SM, Francis DJ, Vishnivetskiy SA, Altenbach C, Klug CS, Hubbell WL, Gurevich VV. Self-association of arrestin family members. Handbook of Experimental Pharmacology. 219: 205-23. PMID 24292832 DOI: 10.1007/978-3-642-41199-1_11  1
2013 Lerch MT, Horwitz J, McCoy J, Hubbell WL. Circular dichroism and site-directed spin labeling reveal structural and dynamical features of high-pressure states of myoglobin. Proceedings of the National Academy of Sciences of the United States of America. 110: E4714-22. PMID 24248390 DOI: 10.1073/pnas.1320124110  1
2013 López CJ, Yang Z, Altenbach C, Hubbell WL. Conformational selection and adaptation to ligand binding in T4 lysozyme cavity mutants. Proceedings of the National Academy of Sciences of the United States of America. 110: E4306-15. PMID 24167295 DOI: 10.1073/pnas.1318754110  1
2013 Song X, Seo J, Baameur F, Vishnivetskiy SA, Chen Q, Kook S, Kim M, Brooks EK, Altenbach C, Hong Y, Hanson SM, Palazzo MC, Chen J, Hubbell WL, Gurevich EV, et al. Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant. Cellular Signalling. 25: 2613-24. PMID 24012956 DOI: 10.1016/j.cellsig.2013.08.022  1
2013 Hubbell WL, López CJ, Altenbach C, Yang Z. Technological advances in site-directed spin labeling of proteins. Current Opinion in Structural Biology. 23: 725-33. PMID 23850140 DOI: 10.1016/j.sbi.2013.06.008  1
2013 Razzaghi S, Brooks EK, Bordignon E, Hubbell WL, Yulikov M, Jeschke G. EPR relaxation-enhancement-based distance measurements on orthogonally spin-labeled T4-lysozyme. Chembiochem : a European Journal of Chemical Biology. 14: 1883-90. PMID 23775845 DOI: 10.1002/cbic.201300165  1
2013 Toledo Warshaviak D, Khramtsov VV, Cascio D, Altenbach C, Hubbell WL. Structure and dynamics of an imidazoline nitroxide side chain with strongly hindered internal motion in proteins. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 232: 53-61. PMID 23694751 DOI: 10.1016/j.jmr.2013.04.013  1
2013 Garbuio L, Bordignon E, Brooks EK, Hubbell WL, Jeschke G, Yulikov M. Orthogonal spin labeling and Gd(III)-nitroxide distance measurements on bacteriophage T4-lysozyme. The Journal of Physical Chemistry. B. 117: 3145-53. PMID 23442004 DOI: 10.1021/jp401806g  1
2013 Vishnivetskiy SA, Chen Q, Palazzo MC, Brooks EK, Altenbach C, Iverson TM, Hubbell WL, Gurevich VV. Engineering visual arrestin-1 with special functional characteristics. The Journal of Biological Chemistry. 288: 3394-405. PMID 23250748 DOI: 10.1074/jbc.M112.445437  1
2012 Francis DJ, Hubbell WL, Klug CS. Probing Protein Secondary Structure using EPR: Investigating a Dynamic Region of Visual Arrestin. Applied Magnetic Resonance. 43: 405-419. PMID 25419051 DOI: 10.1007/s00723-012-0369-y  1
2012 Kim M, Vishnivetskiy SA, Van Eps N, Alexander NS, Cleghorn WM, Zhan X, Hanson SM, Morizumi T, Ernst OP, Meiler J, Gurevich VV, Hubbell WL. Conformation of receptor-bound visual arrestin. Proceedings of the National Academy of Sciences of the United States of America. 109: 18407-12. PMID 23091036 DOI: 10.1073/pnas.1216304109  1
2012 Durer ZA, Kudryashov DS, Sawaya MR, Altenbach C, Hubbell W, Reisler E. Structural states and dynamics of the D-loop in actin. Biophysical Journal. 103: 930-9. PMID 23009842 DOI: 10.1016/j.bpj.2012.07.030  1
2012 López CJ, Oga S, Hubbell WL. Mapping molecular flexibility of proteins with site-directed spin labeling: a case study of myoglobin. Biochemistry. 51: 6568-83. PMID 22809279 DOI: 10.1021/bi3005686  1
2012 Yang Z, Liu Y, Borbat P, Zweier JL, Freed JH, Hubbell WL. Pulsed ESR dipolar spectroscopy for distance measurements in immobilized spin labeled proteins in liquid solution. Journal of the American Chemical Society. 134: 9950-2. PMID 22676043 DOI: 10.1021/ja303791p  1
2011 Fawzi NL, Fleissner MR, Anthis NJ, Kálai T, Hideg K, Hubbell WL, Clore GM. A rigid disulfide-linked nitroxide side chain simplifies the quantitative analysis of PRE data. Journal of Biomolecular Nmr. 51: 105-14. PMID 21947919 DOI: 10.1007/s10858-011-9545-x  1
2011 Fleissner MR, Bridges MD, Brooks EK, Cascio D, Kálai T, Hideg K, Hubbell WL. Structure and dynamics of a conformationally constrained nitroxide side chain and applications in EPR spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 108: 16241-6. PMID 21911399 DOI: 10.1073/pnas.1111420108  1
2011 Van Eps N, Preininger AM, Alexander N, Kaya AI, Meier S, Meiler J, Hamm HE, Hubbell WL. Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit. Proceedings of the National Academy of Sciences of the United States of America. 108: 9420-4. PMID 21606326 DOI: 10.1073/pnas.1105810108  1
2011 Januszyk K, Fleissner MR, Atchabahian L, Shieh FK, Altenbach C, Martin SL, Guo F, Hubbell WL, Clubb RT. Site-directed spin labeling electron paramagnetic resonance study of the ORF1 protein from a mouse L1 retrotransposon. Protein Science : a Publication of the Protein Society. 20: 1231-43. PMID 21563223 DOI: 10.1002/pro.651  1
2011 Vishnivetskiy SA, Gimenez LE, Francis DJ, Hanson SM, Hubbell WL, Klug CS, Gurevich VV. Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins. The Journal of Biological Chemistry. 286: 24288-99. PMID 21471193 DOI: 10.1074/jbc.M110.213835  1
2011 Armstrong BD, Choi J, López C, Wesener DA, Hubbell W, Cavagnero S, Han S. Site-specific hydration dynamics in the nonpolar core of a molten globule by dynamic nuclear polarization of water. Journal of the American Chemical Society. 133: 5987-95. PMID 21443207 DOI: 10.1021/ja111515s  1
2011 Kim M, Hanson SM, Vishnivetskiy SA, Song X, Cleghorn WM, Hubbell WL, Gurevich VV. Robust self-association is a common feature of mammalian visual arrestin-1. Biochemistry. 50: 2235-42. PMID 21288033 DOI: 10.1021/bi1018607  1
2011 McCoy J, Hubbell WL. High-pressure EPR reveals conformational equilibria and volumetric properties of spin-labeled proteins. Proceedings of the National Academy of Sciences of the United States of America. 108: 1331-6. PMID 21205903 DOI: 10.1073/pnas.1017877108  1
2011 Warshaviak DT, Serbulea L, Houk KN, Hubbell WL. Conformational analysis of a nitroxide side chain in an α-helix with density functional theory. The Journal of Physical Chemistry. B. 115: 397-405. PMID 21162593 DOI: 10.1021/jp108871m  1
2011 Kálai T, Fleissner MR, Jek J, Hubbell WL, Hideg K. Synthesis of new spin labels for Cu-free click conjugation Tetrahedron Letters. 52: 2747-2749. DOI: 10.1016/j.tetlet.2011.03.077  1
2010 Van Eps N, Anderson LL, Kisselev OG, Baranski TJ, Hubbell WL, Marshall GR. Electron paramagnetic resonance studies of functionally active, nitroxide spin-labeled peptide analogues of the C-terminus of a G-protein alpha subunit. Biochemistry. 49: 6877-86. PMID 20695526 DOI: 10.1021/bi100846c  1
2010 Zhang Z, Fleissner MR, Tipikin DS, Liang Z, Moscicki JK, Earle KA, Hubbell WL, Freed JH. Multifrequency electron spin resonance study of the dynamics of spin labeled T4 lysozyme. The Journal of Physical Chemistry. B. 114: 5503-21. PMID 20361789 DOI: 10.1021/jp910606h  1
2010 Bridges MD, Hideg K, Hubbell WL. Resolving Conformational and Rotameric Exchange in Spin-Labeled Proteins Using Saturation Recovery EPR. Applied Magnetic Resonance. 37: 363. PMID 20157634 DOI: 10.1007/s00723-009-0079-2  1
2010 Vishnivetskiy SA, Francis D, Van Eps N, Kim M, Hanson SM, Klug CS, Hubbell WL, Gurevich VV. The role of arrestin alpha-helix I in receptor binding. Journal of Molecular Biology. 395: 42-54. PMID 19883657 DOI: 10.1016/j.jmb.2009.10.058  1
2010 Fleissner MR, Brustad EM, Kálai T, Altenbach C, Cascio D, Peters FB, Hideg K, Peuker S, Schultz PG, Hubbell WL. Site-directed spin labeling of a genetically encoded unnatural amino acid (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 51 (21637-21642)) Proceedings of the National Academy of Sciences of the United States of America. 107: 5693. DOI: 10.1073/pnas.1000908107  1
2009 Fleissner MR, Brustad EM, Kálai T, Altenbach C, Cascio D, Peters FB, Hideg K, Peuker S, Schultz PG, Hubbell WL. Site-directed spin labeling of a genetically encoded unnatural amino acid. Proceedings of the National Academy of Sciences of the United States of America. 106: 21637-42. PMID 19995976 DOI: 10.1073/pnas.0912009106  1
2009 López CJ, Fleissner MR, Guo Z, Kusnetzow AK, Hubbell WL. Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins. Protein Science : a Publication of the Protein Society. 18: 1637-52. PMID 19585559 DOI: 10.1002/pro.180  1
2009 Fleissner MR, Cascio D, Hubbell WL. Structural origin of weakly ordered nitroxide motion in spin-labeled proteins. Protein Science : a Publication of the Protein Society. 18: 893-908. PMID 19384990 DOI: 10.1002/pro.96  1
2009 Scoville D, Stamm JD, Altenbach C, Shvetsov A, Kokabi K, Rubenstein PA, Hubbell WL, Reisler E. Effects of binding factors on structural elements in F-actin. Biochemistry. 48: 370-8. PMID 19113841 DOI: 10.1021/bi801649j  1
2009 Kálai T, Hubbell WL, Hideg K. Click reactions with nitroxides Synthesis. 1336-1340. DOI: 10.1055/s-0028-1088018  1
2008 Schwartz TW, Hubbell WL. Structural biology: A moving story of receptors. Nature. 455: 473-4. PMID 18818642 DOI: 10.1038/455473a  1
2008 Hanson SM, Dawson ES, Francis DJ, Van Eps N, Klug CS, Hubbell WL, Meiler J, Gurevich VV. A model for the solution structure of the rod arrestin tetramer. Structure (London, England : 1993). 16: 924-34. PMID 18547524 DOI: 10.1016/j.str.2008.03.006  1
2008 Altenbach C, Kusnetzow AK, Ernst OP, Hofmann KP, Hubbell WL. High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation. Proceedings of the National Academy of Sciences of the United States of America. 105: 7439-44. PMID 18490656 DOI: 10.1073/pnas.0802515105  1
2008 Vamvouka M, Cieslak J, Van Eps N, Hubbell W, Gross A. The structure of the lipid-embedded potassium channel voltage sensor determined by double-electron-electron resonance spectroscopy. Protein Science : a Publication of the Protein Society. 17: 506-17. PMID 18287283 DOI: 10.1110/ps.073310008  1
2008 Epand RF, Zhang YL, Mirzabekov T, Kagan B, Silberstein A, Hubbell WL, Epand RM, Chakraborti S, Dimitrov DS, Anderson WF, Rozenberg-Adler Y. Membrane activity of an amphiphilic alpha-helical membrane-proximal cytoplasmic domain of the MoMuLV envelope glycoprotein. Experimental and Molecular Pathology. 84: 9-17. PMID 18206141 DOI: 10.1016/j.yexmp.2007.11.003  1
2008 Hanson SM, Vishnivetskiy SA, Hubbell WL, Gurevich VV. Opposing effects of inositol hexakisphosphate on rod arrestin and arrestin2 self-association. Biochemistry. 47: 1070-5. PMID 18161994 DOI: 10.1021/bi7021359  1
2008 Guo Z, Cascio D, Hideg K, Hubbell WL. Structural determinants of nitroxide motion in spin-labeled proteins: solvent-exposed sites in helix B of T4 lysozyme. Protein Science : a Publication of the Protein Society. 17: 228-39. PMID 18096642 DOI: 10.1110/ps.073174008  1
2008 Knierim B, Hofmann KP, Gärtner W, Hubbell WL, Ernst OP. Rhodopsin and 9-demethyl-retinal analog: effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors. The Journal of Biological Chemistry. 283: 4967-74. PMID 18063586 DOI: 10.1074/jbc.M703059200  1
2008 Knierim B, Hofmann KP, Gärtner W, Hubbell WL, Ernst OP. Rhodopsin and 9-demethyl-retinal analog: Effect of a partial agonist on displacement of transmembrane helix 6 in class A G protein-coupled receptors (Journal of Biological Chemistry (2008) 283, (4967-4974)) Journal of Biological Chemistry. 283: 16268.  1
2007 Knierim B, Hofmann KP, Ernst OP, Hubbell WL. Sequence of late molecular events in the activation of rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 104: 20290-5. PMID 18077356 DOI: 10.1073/pnas.0710393104  1
2007 Smirnova I, Kasho V, Choe JY, Altenbach C, Hubbell WL, Kaback HR. Sugar binding induces an outward facing conformation of LacY. Proceedings of the National Academy of Sciences of the United States of America. 104: 16504-9. PMID 17925435 DOI: 10.1073/pnas.0708258104  1
2007 Guo Z, Cascio D, Hideg K, Kálái T, Hubbell WL. Structural determinants of nitroxide motion in spin-labeled proteins: tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme. Protein Science : a Publication of the Protein Society. 16: 1069-86. PMID 17473014 DOI: 10.1110/ps.062739107  1
2007 Oldham WM, Van Eps N, Preininger AM, Hubbell WL, Hamm HE. Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins. Proceedings of the National Academy of Sciences of the United States of America. 104: 7927-32. PMID 17463080 DOI: 10.1073/pnas.0702623104  1
2007 Sasaki J, Phillips BJ, Chen X, Van Eps N, Tsai AL, Hubbell WL, Spudich JL. Different dark conformations function in color-sensitive photosignaling by the sensory rhodopsin I-HtrI complex. Biophysical Journal. 92: 4045-53. PMID 17351006 DOI: 10.1529/biophysj.106.101121  1
2007 Hanson SM, Van Eps N, Francis DJ, Altenbach C, Vishnivetskiy SA, Arshavsky VY, Klug CS, Hubbell WL, Gurevich VV. Structure and function of the visual arrestin oligomer. The Embo Journal. 26: 1726-36. PMID 17332750 DOI: 10.1038/sj.emboj.7601614  1
2006 Scoville D, Stamm JD, Toledo-Warshaviak D, Altenbach C, Phillips M, Shvetsov A, Rubenstein PA, Hubbell WL, Reisler E. Hydrophobic loop dynamics and actin filament stability. Biochemistry. 45: 13576-84. PMID 17087511 DOI: 10.1021/bi061229f  1
2006 Van Eps N, Oldham WM, Hamm HE, Hubbell WL. Structural and dynamical changes in an alpha-subunit of a heterotrimeric G protein along the activation pathway. Proceedings of the National Academy of Sciences of the United States of America. 103: 16194-9. PMID 17053066 DOI: 10.1073/pnas.0607972103  1
2006 Cai Q, Kusnetzow AK, Hubbell WL, Haworth IS, Gacho GP, Van Eps N, Hideg K, Chambers EJ, Qin PZ. Site-directed spin labeling measurements of nanometer distances in nucleic acids using a sequence-independent nitroxide probe. Nucleic Acids Research. 34: 4722-30. PMID 16966338 DOI: 10.1093/nar/gkl546  1
2006 Crane JM, Suo Y, Lilly AA, Mao C, Hubbell WL, Randall LL. Sites of interaction of a precursor polypeptide on the export chaperone SecB mapped by site-directed spin labeling. Journal of Molecular Biology. 363: 63-74. PMID 16962134 DOI: 10.1016/j.jmb.2006.07.021  1
2006 Oldham WM, Van Eps N, Preininger AM, Hubbell WL, Hamm HE. Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins. Nature Structural & Molecular Biology. 13: 772-7. PMID 16892066 DOI: 10.1038/nsmb1129  1
2006 Shvetsov A, Stamm JD, Phillips M, Warshaviak D, Altenbach C, Rubenstein PA, Hideg K, Hubbell WL, Reisler E. Conformational dynamics of loop 262-274 in G- and F-actin. Biochemistry. 45: 6541-9. PMID 16700564 DOI: 10.1021/bi052558v  1
2006 Jacobsen K, Hubbell WL, Ernst OP, Risse T. Details of the partial unfolding of T4 lysozyme on quartz using site-directed spin labeling. Angewandte Chemie (International Ed. in English). 45: 3874-7. PMID 16671129 DOI: 10.1002/anie.200600008  1
2006 Kusnetzow AK, Altenbach C, Hubbell WL. Conformational states and dynamics of rhodopsin in micelles and bilayers. Biochemistry. 45: 5538-50. PMID 16634635 DOI: 10.1021/bi060101v  1
2006 Hanson SM, Francis DJ, Vishnivetskiy SA, Kolobova EA, Hubbell WL, Klug CS, Gurevich VV. Differential interaction of spin-labeled arrestin with inactive and active phosphorhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 103: 4900-5. PMID 16547131 DOI: 10.1073/pnas.0600733103  1
2005 Crane JM, Mao C, Lilly AA, Smith VF, Suo Y, Hubbell WL, Randall LL. Mapping of the docking of SecA onto the chaperone SecB by site-directed spin labeling: insight into the mechanism of ligand transfer during protein export. Journal of Molecular Biology. 353: 295-307. PMID 16169560 DOI: 10.1016/j.jmb.2005.08.022  1
2005 Pyka J, Ilnicki J, Altenbach C, Hubbell WL, Froncisz W. Accessibility and dynamics of nitroxide side chains in T4 lysozyme measured by saturation recovery EPR. Biophysical Journal. 89: 2059-68. PMID 15994892 DOI: 10.1529/biophysj.105.059055  1
2005 Altenbach C, Froncisz W, Hemker R, McHaourab H, Hubbell WL. Accessibility of nitroxide side chains: absolute Heisenberg exchange rates from power saturation EPR. Biophysical Journal. 89: 2103-12. PMID 15994891 DOI: 10.1529/biophysj.105.059063  1
2005 Qin PZ, Feigon J, Hubbell WL. Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg(2+)-dependent docking of a GAAA tetraloop. Journal of Molecular Biology. 351: 1-8. PMID 15993422 DOI: 10.1016/j.jmb.2005.06.007  1
2005 Jacobsen K, Oga S, Hubbell WL, Risse T. Determination of the orientation of T4 lysozyme vectorially bound to a planar-supported lipid bilayer using site-directed spin labeling. Biophysical Journal. 88: 4351-65. PMID 15778448 DOI: 10.1529/biophysj.105.059725  1
2005 Klug CS, Camenisch TG, Hubbell WL, Hyde JS. Multiquantum EPR spectroscopy of spin-labeled arrestin K267C at 35 GHz. Biophysical Journal. 88: 3641-7. PMID 15749769 DOI: 10.1529/biophysj.104.054924  1
2004 Kim JM, Altenbach C, Kono M, Oprian DD, Hubbell WL, Khorana HG. Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge. Proceedings of the National Academy of Sciences of the United States of America. 101: 12508-13. PMID 15306683 DOI: 10.1073/pnas.0404519101  1
2004 Columbus L, Hubbell WL. Mapping backbone dynamics in solution with site-directed spin labeling: GCN4-58 bZip free and bound to DNA. Biochemistry. 43: 7273-87. PMID 15182173 DOI: 10.1021/bi0497906  1
2004 Isas JM, Langen R, Hubbell WL, Haigler HT. Structure and dynamics of a helical hairpin that mediates calcium-dependent membrane binding of annexin B12. The Journal of Biological Chemistry. 279: 32492-8. PMID 15143059 DOI: 10.1074/jbc.M402568200  1
2004 Lietzow MA, Hubbell WL. Motion of spin label side chains in cellular retinol-binding protein: correlation with structure and nearest-neighbor interactions in an antiparallel beta-sheet. Biochemistry. 43: 3137-51. PMID 15023065 DOI: 10.1021/bi0360962  1
2004 Liang Z, Lou Y, Freed JH, Columbus L, Hubbell WL. A multifrequency electron spin resonance study of T4 lysozyme dynamics using the slowly relaxing local Structure model Journal of Physical Chemistry B. 108: 17649-17659. DOI: 10.1021/jp0484837  1
2003 Risse T, Hubbell WL, Isas JM, Haigler HT. Structure and dynamics of annexin 12 bound to a planar lipid bilayer. Physical Review Letters. 91: 188101. PMID 14611318  1
2003 Preininger AM, Van Eps N, Yu NJ, Medkova M, Hubbell WL, Hamm HE. The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution. Biochemistry. 42: 7931-41. PMID 12834345 DOI: 10.1021/bi0345438  1
2003 Qin PZ, Hideg K, Feigon J, Hubbell WL. Monitoring RNA base structure and dynamics using site-directed spin labeling. Biochemistry. 42: 6772-83. PMID 12779332 DOI: 10.1021/bi027222p  1
2003 Hubbell WL, Altenbach C, Hubbell CM, Khorana HG. Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking. Advances in Protein Chemistry. 63: 243-90. PMID 12629973 DOI: 10.1016/S0065-3233(03)63010-X  1
2003 Zhang JH, Xiao G, Gunsalus RP, Hubbell WL. Phosphorylation triggers domain separation in the DNA binding response regulator NarL. Biochemistry. 42: 2552-9. PMID 12614149 DOI: 10.1021/bi0272205  1
2003 Kálai T, Jeko J, Hubbell WL, Hideg K. Synthesis of 2,2- and 2,5-disubstituted 1-oxyl pyrrolidine radicals as new homobifunctional cross-linking spin labels Synthesis. 2084-2088.  1
2002 Sutton MD, Guzzo A, Narumi I, Costanzo M, Altenbach C, Ferentz AE, Hubbell WL, Walker GC. A model for the structure of the Escherichia coli SOS-regulated UmuD2 protein. Dna Repair. 1: 77-93. PMID 12509298 DOI: 10.1016/S1568-7864(01)00006-4  1
2002 Serag AA, Altenbach C, Gingery M, Hubbell WL, Yeates TO. Arrangement of subunits and ordering of beta-strands in an amyloid sheet. Nature Structural Biology. 9: 734-9. PMID 12219081 DOI: 10.1038/nsb838  1
2002 Medkova M, Preininger AM, Yu NJ, Hubbell WL, Hamm HE. Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation. Biochemistry. 41: 9962-72. PMID 12146960 DOI: 10.1021/bi0255726  1
2002 Columbus L, Hubbell WL. A new spin on protein dynamics. Trends in Biochemical Sciences. 27: 288-95. PMID 12069788 DOI: 10.1016/S0968-0004(02)02095-9  1
2002 Barnakov A, Altenbach C, Barnakova L, Hubbell WL, Hazelbauer GL. Site-directed spin labeling of a bacterial chemoreceptor reveals a dynamic, loosely packed transmembrane domain. Protein Science : a Publication of the Protein Society. 11: 1472-81. PMID 12021446 DOI: 10.1110/ps.0202502  1
2002 Isas JM, Langen R, Haigler HT, Hubbell WL. Structure and dynamics of a helical hairpin and loop region in annexin 12: a site-directed spin labeling study. Biochemistry. 41: 1464-73. PMID 11814339 DOI: 10.1021/bi011856z  1
2002 Gross A, Hubbell WL. Identification of protein side chains near the membrane-aqueous interface: a site-directed spin labeling study of KcsA. Biochemistry. 41: 1123-8. PMID 11802710 DOI: 10.1021/bi015828s  1
2002 Kálai T, Balog M, Jeko J, Hubbell WL, Hideg K. Palladium-catalyzed coupling reactions of paramagnetic vinyl halides Synthesis. 2365-2372.  1
2001 Altenbach C, Klein-Seetharaman J, Cai K, Khorana HG, Hubbell WL. Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 316 in helix 8 and residues in the sequence 60-75, covering the cytoplasmic end of helices TM1 and TM2 and their connection loop CL1. Biochemistry. 40: 15493-500. PMID 11747424 DOI: 10.1021/bi011545o  1
2001 Altenbach C, Cai K, Klein-Seetharaman J, Khorana HG, Hubbell WL. Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8. Biochemistry. 40: 15483-92. PMID 11747423 DOI: 10.1021/bi011546g  1
2001 Altenbach C, Oh KJ, Trabanino RJ, Hideg K, Hubbell WL. Estimation of inter-residue distances in spin labeled proteins at physiological temperatures: experimental strategies and practical limitations. Biochemistry. 40: 15471-82. PMID 11747422 DOI: 10.1021/bi011544w  1
2001 Cai K, Klein-Seetharaman J, Altenbach C, Hubbell WL, Khorana HG. Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between cysteine pairs engineered in cytoplasmic loops 1, 3, and 4. Biochemistry. 40: 12479-85. PMID 11601971 DOI: 10.1021/bi010747h  1
2001 Klein-Seetharaman J, Hwa J, Cai K, Altenbach C, Hubbell WL, Khorana HG. Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between Cys316 and engineered cysteines in cytoplasmic loop 1. Biochemistry. 40: 12472-8. PMID 11601970 DOI: 10.1021/bi010746p  1
2001 Sokal I, Li N, Klug CS, Filipek S, Hubbell WL, Baehr W, Palczewski K. Calcium-sensitive regions of GCAP1 as observed by chemical modifications, fluorescence, and EPR spectroscopies. The Journal of Biological Chemistry. 276: 43361-73. PMID 11524415 DOI: 10.1074/jbc.M103614200  1
2001 Serag AA, Altenbach C, Gingery M, Hubbell WL, Yeates TO. Identification of a subunit interface in transthyretin amyloid fibrils: evidence for self-assembly from oligomeric building blocks. Biochemistry. 40: 9089-96. PMID 11478875 DOI: 10.1021/bi010655s  1
2001 Qin PZ, Butcher SE, Feigon J, Hubbell WL. Quantitative analysis of the isolated GAAA tetraloop/receptor interaction in solution: a site-directed spin labeling study. Biochemistry. 40: 6929-36. PMID 11389608 DOI: 10.1021/bi010294g  1
2001 Columbus L, Kálai T, Jekö J, Hideg K, Hubbell WL. Molecular motion of spin labeled side chains in alpha-helices: analysis by variation of side chain structure. Biochemistry. 40: 3828-46. PMID 11300763 DOI: 10.1021/bi002645h  1
2001 Voss J, Wu J, Hubbell WL, Jacques V, Meares CF, Kaback HR. Helix packing in the lactose permease of Escherichia coli: distances between site-directed nitroxides and a lanthanide. Biochemistry. 40: 3184-8. PMID 11258934 DOI: 10.1021/bi002333e  1
2000 Zhao M, Kálai T, Hideg K, Altenbach C, Hubbell WL, Kaback HR. Binding of spin-labeled galactosides to the lactose permease of Escherichia coli. Biochemistry. 39: 11381-8. PMID 10985783 DOI: 10.1021/bi001075i  1
2000 Hubbell WL, Cafiso DS, Altenbach C. Identifying conformational changes with site-directed spin labeling. Nature Structural Biology. 7: 735-9. PMID 10966640 DOI: 10.1038/78956  1
2000 Langen R, Oh KJ, Cascio D, Hubbell WL. Crystal structures of spin labeled T4 lysozyme mutants: implications for the interpretation of EPR spectra in terms of structure. Biochemistry. 39: 8396-405. PMID 10913245 DOI: 10.1021/bi000604f  1
2000 Oh KJ, Altenbach C, Collier RJ, Hubbell WL. Site-directed spin labeling of proteins. Applications to diphtheria toxin. Methods in Molecular Biology (Clifton, N.J.). 145: 147-69. PMID 10820721 DOI: 10.1385/1-59259-052-7:147  1
2000 Gaponenko V, Howarth JW, Columbus L, Gasmi-Seabrook G, Yuan J, Hubbell WL, Rosevear PR. Protein global fold determination using site-directed spin and isotope labeling. Protein Science : a Publication of the Protein Society. 9: 302-9. PMID 10716182 DOI: 10.1110/ps.9.2.302  1
2000 Mollaaghababa R, Steinhoff HJ, Hubbell WL, Khorana HG. Time-resolved site-directed spin-labeling studies of bacteriorhodopsin: loop-specific conformational changes in M. Biochemistry. 39: 1120-7. PMID 10653658 DOI: 10.1021/bi991963h  1
1999 Zhao M, Zen KC, Hernandez-Borrell J, Altenbach C, Hubbell WL, Kaback HR. Nitroxide scanning electron paramagnetic resonance of helices IV and V and the intervening loop in the lactose permease of Escherichia coli. Biochemistry. 38: 15970-7. PMID 10625464 DOI: 10.1021/bi991754x  1
1999 Glasgow BJ, Gasymov OK, Abduragimov AR, Yusifov TN, Altenbach C, Hubbell WL. Side chain mobility and ligand interactions of the G strand of tear lipocalins by site-directed spin labeling. Biochemistry. 38: 13707-16. PMID 10521278 DOI: 10.1021/bi9913449  1
1999 Cai K, Klein-Seetharaman J, Hwa J, Hubbell WL, Khorana HG. Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase. Biochemistry. 38: 12893-8. PMID 10504260 DOI: 10.1021/bi9912443  1
1999 Oh KJ, Zhan H, Cui C, Altenbach C, Hubbell WL, Collier RJ. Conformation of the diphtheria toxin T domain in membranes: a site-directed spin-labeling study of the TH8 helix and TL5 loop. Biochemistry. 38: 10336-43. PMID 10441127 DOI: 10.1021/bi990520a  1
1999 Gross A, Columbus L, Hideg K, Altenbach C, Hubbell WL. Structure of the KcsA potassium channel from Streptomyces lividans: a site-directed spin labeling study of the second transmembrane segment. Biochemistry. 38: 10324-35. PMID 10441126 DOI: 10.1021/bi990856k  1
1999 Altenbach C, Klein-Seetharaman J, Hwa J, Khorana HG, Hubbell WL. Structural features and light-dependent changes in the sequence 59-75 connecting helices I and II in rhodopsin: a site-directed spin-labeling study. Biochemistry. 38: 7945-9. PMID 10387037 DOI: 10.1021/bi990014l  1
1999 Klein-Seetharaman J, Hwa J, Cai K, Altenbach C, Hubbell WL, Khorana HG. Single-cysteine substitution mutants at amino acid positions 55-75, the sequence connecting the cytoplasmic ends of helices I and II in rhodopsin: reactivity of the sulfhydryl groups and their derivatives identifies a tertiary structure that changes upon light-activation. Biochemistry. 38: 7938-44. PMID 10387036 DOI: 10.1021/bi990013t  1
1999 Altenbach C, Cai K, Khorana HG, Hubbell WL. Structural features and light-dependent changes in the sequence 306-322 extending from helix VII to the palmitoylation sites in rhodopsin: a site-directed spin-labeling study. Biochemistry. 38: 7931-7. PMID 10387035 DOI: 10.1021/bi9900121  1
1999 Cai K, Klein-Seetharaman J, Farrens D, Zhang C, Altenbach C, Hubbell WL, Khorana HG. Single-cysteine substitution mutants at amino acid positions 306-321 in rhodopsin, the sequence between the cytoplasmic end of helix VII and the palmitoylation sites: sulfhydryl reactivity and transducin activation reveal a tertiary structure. Biochemistry. 38: 7925-30. PMID 10387034 DOI: 10.1021/bi9900119  1
1999 Langen R, Cai K, Altenbach C, Khorana HG, Hubbell WL. Structural features of the C-terminal domain of bovine rhodopsin: a site-directed spin-labeling study. Biochemistry. 38: 7918-24. PMID 10387033 DOI: 10.1021/bi990010g  1
1999 Zhao M, Zen KC, Hubbell WL, Kaback HR. Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli. Biochemistry. 38: 7407-12. PMID 10360937 DOI: 10.1021/bi9906524  1
1999 Barnes JP, Liang Z, Mchaourab HS, Freed JH, Hubbell WL. A multifrequency electron spin resonance study of T4 lysozyme dynamics. Biophysical Journal. 76: 3298-306. PMID 10354455 DOI: 10.1016/S0006-3495(99)77482-5  1
1999 Salwiński L, Hubbell WL. Structure in the channel forming domain of colicin E1 bound to membranes: the 402-424 sequence. Protein Science : a Publication of the Protein Society. 8: 562-72. PMID 10091659 DOI: 10.1110/ps.8.3.562  1
1999 Sun J, Voss J, Hubbell WL, Kaback HR. Proximity between periplasmic loops in the lactose permease of Escherichia coli as determined by site-directed spin labeling. Biochemistry. 38: 3100-5. PMID 10074363 DOI: 10.1021/bi982360t  1
1999 Mchaourab HS, Kálai T, Hideg K, Hubbell WL. Motion of spin-labeled side chains in T4 lysozyme: effect of side chain structure. Biochemistry. 38: 2947-55. PMID 10074347 DOI: 10.1021/bi9826310  1
1998 Langen R, Isas JM, Hubbell WL, Haigler HT. A transmembrane form of annexin XII detected by site-directed spin labeling. Proceedings of the National Academy of Sciences of the United States of America. 95: 14060-5. PMID 9826653 DOI: 10.1073/pnas.95.24.14060  1
1998 Hubbell WL, Gross A, Langen R, Lietzow MA. Recent advances in site-directed spin labeling of proteins. Current Opinion in Structural Biology. 8: 649-56. PMID 9818271 DOI: 10.1016/S0959-440X(98)80158-9  1
1998 Piasecki W, Froncisz W, Hubbell WL. A rectangular loop-gap resonator for EPR studies of aqueous samples. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 134: 36-43. PMID 9740728 DOI: 10.1006/jmre.1998.1482  1
1998 Langen R, Isas JM, Luecke H, Haigler HT, Hubbell WL. Membrane-mediated assembly of annexins studied by site-directed spin labeling. The Journal of Biological Chemistry. 273: 22453-7. PMID 9712869 DOI: 10.1074/jbc.273.35.22453  1
1998 Wang Q, Voss J, Hubbell WL, Kaback HR. Proximity of helices VIII (Ala273) and IX (Met299) in the lactose permease of Escherichia coli. Biochemistry. 37: 4910-5. PMID 9538009 DOI: 10.1021/bi972990f  1
1998 Lin Y, Nielsen R, Murray D, Hubbell WL, Mailer C, Robinson BH, Gelb MH. Docking phospholipase A2 on membranes using electrostatic potential-modulated spin relaxation magnetic resonance. Science (New York, N.Y.). 279: 1925-9. PMID 9506941 DOI: 10.1126/science.279.5358.1925  1
1998 Glasgow BJ, Abduragimov AR, Yusifov TN, Gasymov OK, Horwitz J, Hubbell WL, Faull KF. A conserved disulfide motif in human tear lipocalins influences ligand binding. Biochemistry. 37: 2215-25. PMID 9485367 DOI: 10.1021/bi9720888  1
1998 Voss J, Hubbell WL, Kaback HR. Helix packing in the lactose permease determined by metal-nitroxide interaction Biochemistry. 37: 211-216. PMID 9425041 DOI: 10.1021/bi972152l  1
1997 Kim JM, Altenbach C, Thurmond RL, Khorana HG, Hubbell WL. Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state. Proceedings of the National Academy of Sciences of the United States of America. 94: 14273-8. PMID 9405602 DOI: 10.1073/pnas.94.26.14273  1
1997 Cai K, Langen R, Hubbell WL, Khorana HG. Structure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops. Proceedings of the National Academy of Sciences of the United States of America. 94: 14267-72. PMID 9405601 DOI: 10.1073/pnas.94.26.14267  1
1997 Voss J, Hubbell WL, Hernandez-Borrell J, Kaback HR. Site-directed spin-labeling of transmembrane domain VII and the 4B1 antibody epitope in the lactose permease of Escherichia coli Biochemistry. 36: 15055-15061. PMID 9398232 DOI: 10.1021/bi971726j  1
1997 He MM, Voss J, Hubbell WL, Kaback HR. Arginine 302 (helix IX) in the lactose permease of Escherichia coli is in close proximity to glutamate 269 (helix VIII) as well as glutamate 325 (helix X) Biochemistry. 36: 13682-13687. PMID 9354638 DOI: 10.1021/bi971531b  1
1997 Mchaourab HS, Oh KJ, Fang CJ, Hubbell WL. Conformation of T4 lysozyme in solution. Hinge-bending motion and the substrate-induced conformational transition studied by site-directed spin labeling Biochemistry. 36: 307-316. PMID 9003182 DOI: 10.1021/bi962114m  1
1996 Yang K, Farrens DL, Altenbach C, Farahbakhsh ZT, Hubbell WL, Khorana HG. Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels. Biochemistry. 35: 14040-6. PMID 8916888 DOI: 10.1021/bi962113u  1
1996 Steinhoff HJ, Hubbell WL. Calculation of electron paramagnetic resonance spectra from brownian dynamics trajectories: Application to nitroxide side chains in proteins Biophysical Journal. 71: 2201-2212. PMID 8889196  1
1996 Farrens DL, Altenbach C, Yang K, Hubbell WL, Khorana HG. Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science (New York, N.Y.). 274: 768-70. PMID 8864113 DOI: 10.1126/science.274.5288.768  1
1996 Voss J, He MM, Hubbell WL, Ronald Kaback H. Site-directed spin labeling demonstrates that transmembrane domain XII in the lactose permease of Escherichia coli is an α-helix Biochemistry. 35: 12915-12918. PMID 8841136 DOI: 10.1021/bi9608774  1
1996 Altenbach C, Yang K, Farrens DL, Farahbakhsh ZT, Khorana HG, Hubbell WL. Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study. Biochemistry. 35: 12470-8. PMID 8823182 DOI: 10.1021/bi960849l  1
1996 Yang K, Farrens DL, Hubbell WL, Khorana HG. Structure and function in rhodopsin. Single cysteine substitution mutants in the cytoplasmic interhelical E-F loop region show position-specific effects in transducin activation. Biochemistry. 35: 12464-9. PMID 8823181 DOI: 10.1021/bi960848t  1
1996 Wu J, Voss J, Hubbell WL, Kaback HR. Site-directed spin labeling and chemical crosslinking demonstrate that helix V is close to helices VII and VIII in the lactose permease of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 93: 10123-10127. PMID 8816762 DOI: 10.1073/pnas.93.19.10123  1
1996 Hubbell WL, Mchaourab HS, Altenbach C, Lietzow MA. Watching proteins move using site-directed spin labeling Structure. 4: 779-783. PMID 8805569 DOI: 10.1016/S0969-2126(96)00085-8  1
1996 Wiedau-Pazos M, Trudell JR, Altenbach C, Kane DJ, Hubbell WL, Bredesen DE. Expression of bcl-2 inhibits cellular radical generation. Free Radical Research. 24: 205-12. PMID 8728122  1
1996 Mchaourab HS, Lietzow MA, Hideg K, Hubbell WL. Motion of spin-labeled side chains in T4 lysozyme. Correlation with protein structure and dynamics Biochemistry. 35: 7692-7704. PMID 8672470 DOI: 10.1021/bi960482k  1
1996 Oh KJ, Zhan H, Cui C, Hideg K, Collier RJ, Hubbell WL. Organization of diphtheria toxin T domain in bilayers: a site-directed spin labeling study. Science (New York, N.Y.). 273: 810-2. PMID 8670424  1
1996 Voss J, Hubbell WL, Ronald Kaback H. Helix packing in the lactose permease of escherichia coti as determined by use of designed metal ion binding sites and site-directed gpin labeling Faseb Journal. 10: A144.  1
1995 Voss J, Hubbell WL, Kaback HR. Distance determination in proteins using designed metal ion binding sites and site-directed spin labeling: Application to the lactose permease of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 92: 12300-12303. PMID 8618889 DOI: 10.1073/pnas.92.26.12300  1
1995 Voss J, Salwiński Ł, Kaback HR, Hubbell WL. A method for distance determination in proteins using a designed metal ion binding site and site-directed spin labeling: Evaluation with T4 lysozyme Proceedings of the National Academy of Sciences of the United States of America. 92: 12295-12299. PMID 8618888 DOI: 10.1073/pnas.92.26.12295  1
1995 Farahbakhsh ZT, Huang QL, Ding LL, Altenbach C, Steinhoff HJ, Horwitz J, Hubbell WL. Interaction of alpha-crystallin with spin-labeled peptides. Biochemistry. 34: 509-16. PMID 7819243  1
1995 Jung K, Voss J, He M, Hubbell WL, Kaback HR. Engineering a metal binding site within a polytopic membrane protein, the lactose permease of Escherichia coli Biochemistry®. 34: 6272-6277. PMID 7756253  1
1995 Steinhoff HJ, Mollaaghababa R, Altenbach C, Khorana HG, Hubbell WL. Site directed spin labeling studies of structure and dynamics in bacteriorhodopsin. Biophysical Chemistry. 56: 89-94. PMID 7662873 DOI: 10.1016/0301-4622(95)00019-T  1
1995 Glasgow BJ, Abduragimov AR, Farahbakhsh ZT, Faull KF, Hubbell WL. Tear lipocalins bind a broad array of lipid ligands Current Eye Research. 14: 363-372. PMID 7648862 DOI: 10.3109/02713689508999934  1
1995 Ujwal ML, Jung H, Bibi E, Manoil C, Altenbach C, Hubbell WL, Kaback HR. Membrane topology of helices VII and XI in the lactose permease of Escherichia coli studied by lacY-phoA fusion analysis and site-directed spectroscopy Biochemistry. 34: 14909-14917. PMID 7578103  1
1995 He MM, Voss J, Hubbell WL, Ronald Kaback H. Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 2. Proximity of helix IX (Arg302) with helix X (His322 and Glu325) Biochemistry. 34: 15667-15670. PMID 7495796  1
1995 He MM, Voss J, Hubbell WL, Ronald Kaback H. Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 1. Proximity of helix VII (Asp237 and Asp240) with helices X (Lys319) and XI (Lys358) Biochemistry. 34: 15661-15666. PMID 7495795  1
1995 Hecht JL, Honig B, Shin YK, Hubbell WL. Electrostatic potentials near the surface of DNA: Comparing theory and experiment Journal of Physical Chemistry. 99: 7782-7786.  1
1994 Cornish VW, Benson DR, Altenbach CA, Hideg K, Hubbell WL, Schultz PG. Site-specific incorporation of biophysical probes into proteins. Proceedings of the National Academy of Sciences of the United States of America. 91: 2910-4. PMID 8159678  1
1994 Altenbach C, Greenhalgh DA, Khorana HG, Hubbell WL. A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 91: 1667-71. PMID 8127863  1
1994 Steinhoff HJ, Mollaaghababa R, Altenbach C, Hideg K, Krebs M, Khorana HG, Hubbell WL. Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin. Science (New York, N.Y.). 266: 105-7. PMID 7939627  1
1994 Hubbell WL, Altenbach C. Investigation of structure and dynamics in membrane proteins using site-directed spin labeling Current Opinion in Structural Biology. 4: 566-573. DOI: 10.1016/S0959-440X(94)90219-4  1
1993 Perozo E, Hubbell WL. Voltage activation of reconstituted sodium channels: use of bacteriorhodopsin as a light-driven current source. Biochemistry. 32: 10471-8. PMID 8399193 DOI: 10.1021/bi00090a025  1
1993 Franklin JC, Cafiso DS, Flewelling RF, Hubbell WL. Probes of membrane electrostatics: synthesis and voltage-dependent partitioning of negative hydrophobic ion spin labels in lipid vesicles. Biophysical Journal. 64: 642-53. PMID 8386011 DOI: 10.1016/S0006-3495(93)81423-1  1
1993 Shin YK, Levinthal C, Levinthal F, Hubbell WL. Colicin E1 binding to membranes: time-resolved studies of spin-labeled mutants. Science (New York, N.Y.). 259: 960-3. PMID 8382373  1
1993 Farahbakhsh ZT, Hideg K, Hubbell WL. Photoactivated conformational changes in rhodopsin: A time-resolved spin label study Science. 262: 1416-1419. PMID 8248781  1
1993 Resek JF, Farahbakhsh ZT, Hubbell WL, Khorana HG. Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin. Biochemistry. 32: 12025-32. PMID 8218279 DOI: 10.1021/bi00096a012  1
1993 Wu G, Hubbell WL. Phospholipid asymmetry and transmembrane diffusion in photoreceptor disc membranes Biochemistry. 32: 879-888.  1
1992 Farahbakhsh ZT, Altenbach C, Hubbell WL. Spin labeled cysteines as sensors for protein-lipid interaction and conformation in rhodopsin Photochemistry and Photobiology. 56: 1019-1033. PMID 1492127  1
1992 Shin YK, Hubbell WL. Determination of electrostatic potentials at biological interfaces using electron-electron double resonance Biophysical Journal. 61: 1443-1453. PMID 1319760  1
1992 Anthony-Cahill SJ, Benfield PA, Fairman R, Wasserman ZR, Brenner SL, Stafford WF, Altenbach C, Hubbell WL, DeGrado WF. Molecular characterization of helix-loop-helix peptides. Science (New York, N.Y.). 255: 979-83. PMID 1312255  1
1991 Trudell JR, Costa AK, Hubbell WL. Inhibition of protein kinase C by local anesthetics Annals of the New York Academy of Sciences. 625: 743-746. PMID 2058922  1
1991 Levinthal F, Todd AP, Hubbell WL, Levinthal C. A single tryptic fragment of colicin E1 can form an ion channel: stoichiometry confirms kinetics. Proteins. 11: 254-62. PMID 1722045 DOI: 10.1002/prot.340110404  1
1991 Greenhalgh DA, Altenbach C, Hubbell WL, Khorana HG. Locations of Arg-82, Asp-85, and Asp-96 in helix C of bacteriorhodopsin relative to the aqueous boundaries. Proceedings of the National Academy of Sciences of the United States of America. 88: 8626-30. PMID 1656452 DOI: 10.1073/pnas.88.19.8626  1
1990 Hubbell WL. Transbilayer coupling mechanism for the formation of lipid asymmetry in biological membranes. Application to the photoreceptor disc membrane Biophysical Journal. 57: 99-108. PMID 2297564  1
1990 Oldenburg KR, Hubbell WL. Invertebrate rhodopsin cleavage by an endogenous calcium activated protease Experimental Eye Research. 51: 463-472. PMID 2209756 DOI: 10.1016/0014-4835(90)90159-R  1
1990 Altenbach C, Marti T, Khorana HG, Hubbell WL. Transmembrane protein structure: Spin labeling of bacteriorhodopsin mutants Science. 248: 1088-1092. PMID 2160734  1
1990 Tsui FC, Sundberg SA, Hubbell WL. Distribution of charge on photoreceptor disc membranes and implications for charged lipid asymmetry Biophysical Journal. 57: 85-97. PMID 2153422  1
1989 Todd AP, Cong J, Levinthal F, Levinthal C, Hubbell WL. Site-directed mutagenesis of colicin E1 provides specific attachment sites for spin labels whose spectra are sensitive to local conformation. Proteins. 6: 294-305. PMID 2560193 DOI: 10.1002/prot.340060312  1
1989 Altenbach C, Froncisz W, Hyde JS, Hubbell WL. Conformation of spin-labeled melittin at membrane surfaces investigated by pulse saturation recovery and continuous wave power saturation electron paramagnetic resonance. Biophysical Journal. 56: 1183-91. PMID 2558734 DOI: 10.1016/S0006-3495(89)82765-1  1
1989 Altenbach C, Flitsch SL, Khorana HG, Hubbell WL. Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines. Biochemistry. 28: 7806-12. PMID 2558712  1
1988 Altenbach C, Hubbell WL. The aggregation state of spin-labeled melittin in solution and bound to phospholipid membranes: Evidence that membrane-bound melittin is monomeric Proteins: Structure, Function and Genetics. 3: 230-242. PMID 2843850  1
1987 Hubbell WL, Froncisz W, Hyde JS. Continuous and stopped flow EPR spectrometer based on a loop gap resonator Review of Scientific Instruments. 58: 1879-1886. DOI: 10.1063/1.1139536  1
1986 Flewelling RF, Hubbell WL. The membrane dipole potential in a total membrane potential model. Applications to hydrophobic ion interactions with membranes Biophysical Journal. 49: 541-552. PMID 3955184  1
1986 Sundberg SA, Hubbell WL. Investigation of surface potential asymmetry in phospholipid vesicles by a spin label relaxation method Biophysical Journal. 49: 553-562. PMID 3006815  1
1986 Flewelling RF, Hubbell WL. Hydrophobic ion interactions with membranes. Thermodynamic analysis of tetraphenylphosphonium binding to vesicles Biophysical Journal. 49: 531-540. PMID 3006814  1
1986 Honig BH, Hubbell WL, Flewelling RF. Electrostatic interactions in membranes and proteins. Annual Review of Biophysics and Biophysical Chemistry. 15: 163-93. PMID 2424473 DOI: 10.1146/annurev.bb.15.060186.001115  1
1986 Tsui FC, Ojcius DM, Hubbell WL. The intrinsic pK(a) values for phosphatidylserine and phosphatidylethanolamine in phosphatidylcholine host bilayers Biophysical Journal. 49: 459-468.  1
1985 Baldwin PA, Hubbell WL. Effects of lipid environment on the light-induced conformational changes of rhodopsin. 2. Roles of lipid chain length, unsaturation, and phase state Biochemistry. 24: 2633-2639. PMID 4027218  1
1984 Honig BH, Hubbell WL. Stability of "salt bridges" in membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 81: 5412-6. PMID 6591197  1
1983 Cafiso DS, Hubbell WL. Electrogenic H+/OH- movement across phospholipid vesicles measured by spin-labeled hydrophobic ions. Biophysical Journal. 44: 49-57. PMID 6313085  1
1982 Cafiso DS, Hubbell WL. Transmembrane electrical currents of spin-labeled hydrophobic ions. Biophysical Journal. 39: 263-72. PMID 7139025 DOI: 10.1016/S0006-3495(82)84516-5  1
1982 Fung BKK, Hubbell WL. [39] Iodination of rhodopsin and transmembrane topology Methods in Enzymology. 81: 269-275. PMID 7098869 DOI: 10.1016/S0076-6879(82)81041-0  1
1982 Hong K, Knudsen PJ, Hubbell WL. [22] Purification of rhodopsin on hydroxyapatite columns, detergent exchange, and recombination with phospholipids Methods in Enzymology. 81: 144-150. PMID 6285125 DOI: 10.1016/S0076-6879(82)81024-0  1
1981 Cafiso DS, Hubbell WL. EPR determination of membrane potentials. Annual Review of Biophysics and Bioengineering. 10: 217-44. PMID 6266334 DOI: 10.1146/annurev.bb.10.060181.001245  1
1980 Cafiso DS, Hubbell WL. Interfacial charge separation in photoreceptor memebranes. Photochemistry and Photobiology. 32: 461-8. PMID 7454850  1
1980 Cafiso DS, Hubbell WL. Light-induced interfacial potentials in photoreceptor membranes. Biophysical Journal. 30: 243-63. PMID 6266528 DOI: 10.1016/S0006-3495(80)85092-2  1
1978 Cafiso DS, Hubbell WL. Estimation of transmembrane potentials from phase equilibria of hydrophobic paramagnetic ions. Biochemistry. 17: 187-95. PMID 201283  1
1978 Cafiso DS, Hubbell WL. Estimation of transmembrane pH gradients from phase equilibria of spin-labeled amines. Biochemistry. 17: 3871-7. PMID 29663  1
1976 Castle JD, Hubbell WL. Estimation of membrane surface potential and charge density from the phase equilibrium of a paramagnetic amphiphile. Biochemistry. 15: 4818-31. PMID 186095  1
1973 Shimshick EJ, Kleemann W, Hubbell WL, McConnell HM. Lateral phase separations in membranes. Journal of Supramolecular Structure. 1: 285-94. PMID 4588281 DOI: 10.1002/jss.400010406  1
1971 Hubbell WL, McConnell HM. Molecular motion in spin-labeled phospholipids and membranes. Journal of the American Chemical Society. 93: 314-26. PMID 5541516  1
1970 Hubbell WL, Metcalfe JC, Metcalfe SM, McConnell HM. The interaction of small molecules with spin-labelled erythrocyte membranes. Biochimica Et Biophysica Acta. 219: 415-27. PMID 4322299  1
1970 Rottem S, Hubbell WL, Hayflick L, McConnell HM. Motion of fatty acid spin labels in the plasma membrane of mycoplasma. Biochimica Et Biophysica Acta. 219: 104-13. PMID 4319690  1
1969 Hubbell WL, McConnell HM. Motion of steroid spin labels in membranes. Proceedings of the National Academy of Sciences of the United States of America. 63: 16-22. PMID 16591744  1
1969 Hubbell WL, McConnell HM. Orientation and motion of amphiphilic spin labels in membranes. Proceedings of the National Academy of Sciences of the United States of America. 64: 20-7. PMID 4312749  1
1969 Hubbell WL, McConnell HM, Metcalfe JC. Magnetic resonance studies of anaesthetics in cyto-membranes. British Journal of Pharmacology. 35: P374-5. PMID 4304428  1
1968 Hubbell WL, McConnell HM. Spin-label studies of the excitable membranes of nerve and muscle. Proceedings of the National Academy of Sciences of the United States of America. 61: 12-6. PMID 4301585  1
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