Year |
Citation |
Score |
2017 |
Kendall D, Alexander S, Priestley R, Asghar M, Mentzer Bv. S3/1Biased Agonism at Cannabinoid CB1 and δ-Opioid Receptors; Therapeutic Potential Neuropeptides. 65: 131. DOI: 10.1016/J.Npep.2017.02.011 |
0.526 |
|
2015 |
Alexander SP, Catterall WA, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA. The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels. British Journal of Pharmacology. 172: 5904-5941. PMID 26650441 DOI: 10.1111/Bph.13349 |
0.317 |
|
2015 |
Alexander SP, Davenport AP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA, Collaborators C. The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors. British Journal of Pharmacology. 172: 5744-5869. PMID 26650439 DOI: 10.1111/Bph.13348 |
0.337 |
|
2015 |
Jean-Gilles L, Braitch M, Latif ML, Aram J, Fahey AJ, Edwards LJ, Robins RA, Tanasescu R, Tighe PJ, Gran B, Showe LC, Alexander SP, Chapman V, Kendall DA, Constantinescu CS. Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells. Acta Physiologica (Oxford, England). 214: 63-74. PMID 25704169 DOI: 10.1111/Apha.12474 |
0.597 |
|
2015 |
Priestley RS, Nickolls SA, Alexander SP, Kendall DA. A potential role for cannabinoid receptors in the therapeutic action of fenofibrate. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1446-55. PMID 25550466 DOI: 10.1096/Fj.14-263053 |
0.522 |
|
2014 |
Hassan S, Eldeeb K, Millns PJ, Bennett AJ, Alexander SP, Kendall DA. Cannabidiol enhances microglial phagocytosis via transient receptor potential (TRP) channel activation. British Journal of Pharmacology. 171: 2426-39. PMID 24641282 DOI: 10.1111/Bph.12615 |
0.476 |
|
2013 |
Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ. The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors. British Journal of Pharmacology. 170: 1676-705. PMID 24528241 DOI: 10.1111/Bph.12449 |
0.349 |
|
2013 |
Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ. The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors. British Journal of Pharmacology. 170: 1652-75. PMID 24528240 DOI: 10.1111/Bph.12448 |
0.348 |
|
2013 |
Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Catterall WA, Spedding M, Peters JA, Harmar AJ. The Concise Guide to PHARMACOLOGY 2013/14: ion channels. British Journal of Pharmacology. 170: 1607-51. PMID 24528239 DOI: 10.1111/Bph.12447 |
0.332 |
|
2013 |
Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ. The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels. British Journal of Pharmacology. 170: 1582-606. PMID 24528238 DOI: 10.1111/Bph.12446 |
0.33 |
|
2013 |
Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, Peters JA, Harmar AJ. The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors. British Journal of Pharmacology. 170: 1459-581. PMID 24517644 DOI: 10.1111/Bph.12445 |
0.355 |
|
2012 |
Woodhams SG, Wong A, Barrett DA, Bennett AJ, Chapman V, Alexander SP. Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat. British Journal of Pharmacology. 167: 1609-19. PMID 22924700 DOI: 10.1111/J.1476-5381.2012.02179.X |
0.436 |
|
2012 |
Okine BN, Norris LM, Woodhams S, Burston J, Patel A, Alexander SP, Barrett DA, Kendall DA, Bennett AJ, Chapman V. Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system. British Journal of Pharmacology. 167: 627-40. PMID 22595021 DOI: 10.1111/J.1476-5381.2012.02028.X |
0.56 |
|
2011 |
Sarmad S, Alexander SP, Barrett DA, Marsden CA, Kendall DA. Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices. Journal of Neurochemistry. 117: 665-77. PMID 21375532 DOI: 10.1111/J.1471-4159.2011.07235.X |
0.473 |
|
2010 |
Sagar DR, Staniaszek LE, Okine BN, Woodhams S, Norris LM, Pearson RG, Garle MJ, Alexander SP, Bennett AJ, Barrett DA, Kendall DA, Scammell BE, Chapman V. Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. Arthritis and Rheumatism. 62: 3666-76. PMID 20722027 DOI: 10.1002/Art.27698 |
0.566 |
|
2009 |
Alexander SP, Kendall DA. The life cycle of the endocannabinoids: formation and inactivation. Current Topics in Behavioral Neurosciences. 1: 3-35. PMID 21104378 DOI: 10.1007/978-3-540-88955-7_1 |
0.415 |
|
2009 |
Guasti L, Richardson D, Jhaveri M, Eldeeb K, Barrett D, Elphick MR, Alexander SP, Kendall D, Michael GJ, Chapman V. Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. Molecular Pain. 5: 35. PMID 19570201 DOI: 10.1186/1744-8069-5-35 |
0.544 |
|
2008 |
Jhaveri MD, Richardson D, Robinson I, Garle MJ, Patel A, Sun Y, Sagar DR, Bennett AJ, Alexander SP, Kendall DA, Barrett DA, Chapman V. Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain. Neuropharmacology. 55: 85-93. PMID 18534634 DOI: 10.1016/J.Neuropharm.2008.04.018 |
0.61 |
|
2008 |
Cordeaux Y, Briddon SJ, Alexander SP, Kellam B, Hill SJ. Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 850-60. PMID 17959910 DOI: 10.1096/Fj.07-8180Com |
0.451 |
|
2007 |
Athanasiou A, Clarke AB, Turner AE, Kumaran NM, Vakilpour S, Smith PA, Bagiokou D, Bradshaw TD, Westwell AD, Fang L, Lobo DN, Constantinescu CS, Calabrese V, Loesch A, Alexander SP, et al. Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications. 364: 131-7. PMID 17931597 DOI: 10.1016/J.Bbrc.2007.09.107 |
0.451 |
|
2007 |
Sun Y, Alexander SP, Garle MJ, Gibson CL, Hewitt K, Murphy SP, Kendall DA, Bennett AJ. Cannabinoid activation of PPAR alpha; a novel neuroprotective mechanism. British Journal of Pharmacology. 152: 734-43. PMID 17906680 DOI: 10.1038/Sj.Bjp.0707478 |
0.459 |
|
2007 |
Alexander SP, Kendall DA. The complications of promiscuity: endocannabinoid action and metabolism. British Journal of Pharmacology. 152: 602-23. PMID 17876303 DOI: 10.1038/Sj.Bjp.0707456 |
0.418 |
|
2007 |
Athanasiou A, Smith PA, Vakilpour S, Kumaran NM, Turner AE, Bagiokou D, Layfield R, Ray DE, Westwell AD, Alexander SP, Kendall DA, Lobo DN, Watson SA, Lophatanon A, Muir KA, et al. Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochemical and Biophysical Research Communications. 354: 50-5. PMID 17214968 DOI: 10.1016/J.Bbrc.2006.12.179 |
0.512 |
|
2007 |
Rayment SJ, Ralevic V, Barrett DA, Cordell R, Alexander SP. A novel mechanism of vasoregulation: ADP-induced relaxation of the porcine isolated coronary artery is mediated via adenosine release. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 577-85. PMID 17167068 DOI: 10.1096/fj.06-7050com |
0.332 |
|
2006 |
Sun Y, Alexander SP, Kendall DA, Bennett AJ. Cannabinoids and PPARalpha signalling. Biochemical Society Transactions. 34: 1095-7. PMID 17073758 DOI: 10.1042/Bst0341095 |
0.507 |
|
2006 |
Alexander SP. Flavonoids as antagonists at A1 adenosine receptors. Phytotherapy Research : Ptr. 20: 1009-12. PMID 17006974 DOI: 10.1002/ptr.1975 |
0.364 |
|
2006 |
Alexander SP, Mathie A, Peters JA. Guide to receptors and channels, 2nd edition. British Journal of Pharmacology. 147: S1-168. PMID 16550176 DOI: 10.1038/Sj.Bjp.0706651 |
0.332 |
|
2005 |
Kendall DA, Alexander SP. Assay of receptor-stimulated phosphoinositide turnover. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit2.7. PMID 21953390 DOI: 10.1002/0471141755.Ph0207S30 |
0.53 |
|
2005 |
Goldring WP, Alexander SP, Kendall DA, Pattenden G. Novel phomactin analogues as PAF receptor ligands. Bioorganic & Medicinal Chemistry Letters. 15: 3263-6. PMID 15922596 DOI: 10.1016/J.Bmcl.2005.04.048 |
0.499 |
|
2005 |
De Bank PA, Kendall DA, Alexander SP. A spectrophotometric assay for fatty acid amide hydrolase suitable for high-throughput screening. Biochemical Pharmacology. 69: 1187-93. PMID 15794939 DOI: 10.1016/J.Bcp.2005.01.012 |
0.681 |
|
2003 |
Dickenson JM, Reeder S, Rees B, Alexander S, Kendall D. Functional expression of adenosine A2A and A3 receptors in the mouse dendritic cell line XS-106 European Journal of Pharmacology. 474: 43-51. PMID 12909194 DOI: 10.1016/S0014-2999(03)02041-7 |
0.445 |
|
1999 |
Alexander S, Peters J, Mead A, Lewis S. TiPS Receptor and Ion Channel Nomenclature Supplement 1999 Trends in Pharmacological Sciences. 19: 1. DOI: 10.1016/S0165-6147(99)80001-7 |
0.318 |
|
1998 |
Haynes JM, Alexander SP, Hill SJ. A1 and A2 adenosine receptor modulation of contractility in the cauda epididymis of the guinea-pig. British Journal of Pharmacology. 125: 570-6. PMID 9806342 DOI: 10.1038/Sj.Bjp.0702095 |
0.542 |
|
1998 |
Haynes JM, Alexander SP, Hill SJ. A1 adenosine receptor modulation of electrically-evoked contractions in the bisected vas deferens and cauda epididymis of the guinea-pig. British Journal of Pharmacology. 124: 964-70. PMID 9692782 DOI: 10.1038/Sj.Bjp.0701909 |
0.504 |
|
1997 |
Cooper J, Hill SJ, Alexander SP. An endogenous A2B adenosine receptor coupled to cyclic AMP generation in human embryonic kidney (HEK 293) cells. British Journal of Pharmacology. 122: 546-50. PMID 9351513 DOI: 10.1038/Sj.Bjp.0701401 |
0.507 |
|
1997 |
Cadogan AK, Alexander SP, Boyd EA, Kendall DA. Influence of cannabinoids on electrically evoked dopamine release and cyclic AMP generation in the rat striatum. Journal of Neurochemistry. 69: 1131-7. PMID 9282935 DOI: 10.1046/J.1471-4159.1997.69031131.X |
0.485 |
|
1997 |
Neil KE, Hernández F, Kendall DA, Alexander SP. Heterogeneity of beta-adrenoceptors in guinea-pig brain: radioligand binding and cyclic nucleotide generation. Journal of Neurochemistry. 68: 2610-7. PMID 9166759 DOI: 10.1046/J.1471-4159.1997.68062610.X |
0.442 |
|
1996 |
Randall MD, Alexander SP, Bennett T, Boyd EA, Fry JR, Gardiner SM, Kemp PA, McCulloch AI, Kendall DA. An endogenous cannabinoid as an endothelium-derived vasorelaxant. Biochemical and Biophysical Research Communications. 229: 114-20. PMID 8954092 DOI: 10.1006/Bbrc.1996.1766 |
0.492 |
|
1996 |
Alexander SP, Cooper J, Shine J, Hill SJ. Characterization of the human brain putative A2B adenosine receptor expressed in Chinese hamster ovary (CHO.A2B4) cells. British Journal of Pharmacology. 119: 1286-90. PMID 8937736 DOI: 10.1111/J.1476-5381.1996.Tb16035.X |
0.505 |
|
1996 |
Neil KE, Kendall DA, Alexander SP. Coupling of metabotropic glutamate receptors to phosphoinositide mobilisation and inhibition of cyclic AMP generation in the guinea-pig cerebellum. British Journal of Pharmacology. 118: 311-6. PMID 8735632 DOI: 10.1111/J.1476-5381.1996.Tb15404.X |
0.506 |
|
1995 |
Losinski A, Alexander SP. Adenosine receptor-mediated relaxation of guinea-pig precontracted, isolated trachea. British Journal of Pharmacology. 116: 2425-8. PMID 8581279 |
0.312 |
|
1995 |
Cooper JA, Hill SJ, Alexander SP, Rubin PC, Horn EH. Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets. British Journal of Clinical Pharmacology. 40: 43-50. PMID 8527267 DOI: 10.1111/J.1365-2125.1995.Tb04533.X |
0.497 |
|
1994 |
Iredale PA, Alexander SP, Hill SJ. Coupling of a transfected human brain A1 adenosine receptor in CHO-K1 cells to calcium mobilisation via a pertussis toxin-sensitive mechanism. British Journal of Pharmacology. 111: 1252-6. PMID 8032613 DOI: 10.1111/J.1476-5381.1994.Tb14880.X |
0.508 |
|
1994 |
Cartmell J, Kemp JA, Alexander SP, Shinozaki H, Kendall DA. Modulation of cyclic AMP formation by putative metabotropic receptor agonists. British Journal of Pharmacology. 111: 364-9. PMID 8012720 DOI: 10.1111/J.1476-5381.1994.Tb14069.X |
0.54 |
|
1994 |
Alexander SP, Losinski A, Kendall DA, Hill SJ. A comparison of A2 adenosine receptor-induced cyclic AMP generation in cerebral cortex and relaxation of pre-contracted aorta. British Journal of Pharmacology. 111: 185-90. PMID 8012695 DOI: 10.1111/J.1476-5381.1994.Tb14042.X |
0.648 |
|
1994 |
Alexander SP, Curtis AR, Kendall DA, Hill SJ. A1 adenosine receptor inhibition of cyclic AMP formation and radioligand binding in the guinea-pig cerebral cortex. British Journal of Pharmacology. 113: 1501-7. PMID 7889308 DOI: 10.1111/J.1476-5381.1994.Tb17166.X |
0.639 |
|
1994 |
Hernández F, Alexander SP, Kendall DA. Natriuretic peptide-induced cyclic GMP accumulation in adult guinea-pig cerebellar slices. British Journal of Pharmacology. 113: 216-20. PMID 7812614 DOI: 10.1111/J.1476-5381.1994.Tb16196.X |
0.479 |
|
1994 |
Hernández F, Alexander SP, Kendall DA. Forskolin and 3-isobutyl-1-methylxanthine increase basal and sodium nitroprusside-elevated cyclic GMP levels in adult guinea-pig cerebellar slices. Journal of Neurochemistry. 62: 2212-8. PMID 7514648 DOI: 10.1046/J.1471-4159.1994.62062212.X |
0.475 |
|
1993 |
Cartmell J, Curtis AR, Kemp JA, Kendall DA, Alexander SP. Subtypes of metabotropic excitatory amino acid receptor distinguished by stereoisomers of the rigid glutamate analogue, 1-aminocyclopentane-1,3-dicarboxylate. Neuroscience Letters. 153: 107-10. PMID 8390029 DOI: 10.1016/0304-3940(93)90088-3 |
0.515 |
|
1993 |
Cartmell J, Kemp JA, Alexander SP, Kendall DA. Endogenous adenosine regulates the apparent efficacy of 1-aminocyclopentyl-1S,3R-dicarboxylate inhibition of forskolin-stimulated cyclic AMP accumulation in rat cerebral cortical slices. Journal of Neurochemistry. 60: 780-2. PMID 8380444 DOI: 10.1111/J.1471-4159.1993.Tb03218.X |
0.51 |
|
1993 |
Hernández F, Kendall DA, Alexander SP. Adenosine receptor-induced second messenger production in adult guinea-pig cerebellum. British Journal of Pharmacology. 110: 1085-90. PMID 8298796 DOI: 10.1111/J.1476-5381.1993.Tb13925.X |
0.578 |
|
1992 |
Iredale PA, Martin KF, Alexander SP, Hill SJ, Kendall DA. Inositol 1,4,5-trisphosphate generation and calcium mobilisation via activation of an atypical P2 receptor in the neuronal cell line, N1E-115. British Journal of Pharmacology. 107: 1083-7. PMID 1467830 DOI: 10.1111/J.1476-5381.1992.Tb13410.X |
0.615 |
|
1992 |
Iredale PA, Martin KF, Alexander SP, Hill SJ, Kendall DA. Qualitative differences in [Ca2+]i increases and InsP3 generation following stimulation of N1E-115 cells with micromolar and millimolar ATP. Biochemical Pharmacology. 44: 1479-87. PMID 1417971 DOI: 10.1016/0006-2952(92)90461-Q |
0.586 |
|
1992 |
Alexander SP, Kendall DA, Hill SJ. Excitatory amino acid-induced phosphoinositide turnover in guinea pig cerebral cortical slices: selective enhancement by spermine of the response to DL-1-aminocyclopentane-trans-1,3-dicarboxylate. Journal of Neurochemistry. 59: 610-5. PMID 1352801 DOI: 10.1111/J.1471-4159.1992.Tb09413.X |
0.641 |
|
1992 |
White TE, Dickenson JM, Alexander SP, Hill SJ. Adenosine A1-receptor stimulation of inositol phospholipid hydrolysis and calcium mobilisation in DDT1 MF-2 cells. British Journal of Pharmacology. 106: 215-21. PMID 1324066 DOI: 10.1111/J.1476-5381.1992.Tb14317.X |
0.537 |
|
1992 |
Alexander SP, Kendall DA, Hill SJ. Spermine enhances calcium- and GTP analogue-stimulated particulate phosphoinositidase. Biochemical Society Transactions. 20: 20S. PMID 1321751 DOI: 10.1042/Bst020020S |
0.555 |
|
1992 |
Cartmell J, Kemp JA, Alexander SP, Hill SJ, Kendall DA. Inhibition of forskolin-stimulated cyclic AMP formation by 1-aminocyclopentane-trans-1,3-dicarboxylate in guinea-pig cerebral cortical slices. Journal of Neurochemistry. 58: 1964-6. PMID 1313857 DOI: 10.1111/J.1471-4159.1992.Tb10077.X |
0.631 |
|
1992 |
Alexander SP, Curtis AR, Hill SJ, Kendall DA. Activation of a metabotropic excitatory amino acid receptor potentiates A2b adenosine receptor-stimulated cyclic AMP accumulation. Neuroscience Letters. 146: 231-3. PMID 1283452 DOI: 10.1016/0304-3940(92)90085-L |
0.622 |
|
1991 |
Alexander SP, Hill SJ, Kendall DA. Do polyamines regulate the NMDA inhibition of muscarinic receptor-induced phosphoinositide turnover in guinea pig brain? Neuroscience Letters. 131: 167-70. PMID 1662340 DOI: 10.1016/0304-3940(91)90605-S |
0.627 |
|
1991 |
Alexander SP, J Hill S, Kendall DA. Adenosine receptor modulation of inositol phospholipid turnover in the central nervous system Nucleosides and Nucleotides. 10: 1113-1116. DOI: 10.1080/07328319108047249 |
0.573 |
|
1990 |
Alexander SP, Hill SJ, Kendall DA. Differential effects of elevated calcium ion concentrations on inositol phospholipid responses in mouse and rat cerebral cortical slices. Biochemical Pharmacology. 40: 1793-9. PMID 2173588 DOI: 10.1016/0006-2952(90)90358-R |
0.6 |
|
1990 |
Alexander SP, Hill SJ, Kendall DA. Is the adenosine receptor modulation of histamine-induced accumulation of inositol phosphates in cerebral cortical slices mediated by effects on calcium ion fluxes? Journal of Neurochemistry. 55: 1138-41. PMID 2118942 DOI: 10.1111/J.1471-4159.1990.Tb03116.X |
0.628 |
|
1990 |
Alexander SP, Hill SJ, Kendall DA. Excitatory amino acid-induced formation of inositol phosphates in guinea-pig cerebral cortical slices: involvement of ionotropic or metabotropic receptors? Journal of Neurochemistry. 55: 1439-41. PMID 1975837 DOI: 10.1111/J.1471-4159.1990.Tb03158.X |
0.595 |
|
1989 |
Alexander SP, Reddington M. The cellular localization of adenosine receptors in rat neostriatum. Neuroscience. 28: 645-51. PMID 2710337 DOI: 10.1016/0306-4522(89)90011-0 |
0.633 |
|
1989 |
Alexander SP, Hill SJ, Kendall DA. The 2-chloroadenosine inhibition of histamine-induced inositol phosphates accumulation in mouse brain and calcium ions. British Journal of Pharmacology. 98: 832P. PMID 2611535 |
0.551 |
|
1989 |
Alexander SP, Kendall DA, Hill SJ. Differences in the adenosine receptors modulating inositol phosphates and cyclic AMP accumulation in mammalian cerebral cortex. British Journal of Pharmacology. 98: 1241-8. PMID 2482102 DOI: 10.1111/J.1476-5381.1989.Tb12670.X |
0.658 |
|
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