Lori Broderick, Ph.D. - Publications

Affiliations: 
2005 Microbiology and Immunology State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Immunology

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Luu I, Sharma A, Guaderrama M, Peru M, Nation J, Page N, Carvalho D, Magit A, Jiang W, Leuin S, Bliss M, Bothwell M, Brigger M, Kearns D, Newbury R, ... ... Broderick L, et al. Immune Dysregulation in the Tonsillar Microenvironment of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis (PFAPA) Syndrome. Journal of Clinical Immunology. PMID 31807979 DOI: 10.1007/S10875-019-00724-2  0.366
2019 Broderick L, Yost S, Li D, McGeough MD, Booshehri LM, Guaderrama M, Brydges SD, Kucharova K, Patel NC, Harr M, Hakonarson H, Zackai E, Cowell IG, Austin CA, Hügle B, et al. Mutations in topoisomerase IIβ result in a B cell immunodeficiency. Nature Communications. 10: 3644. PMID 31409799 DOI: 10.1038/S41467-019-11570-6  0.315
2018 Hoffman HM, Broderick L. JAK inhibitors in autoinflammation. The Journal of Clinical Investigation. PMID 29889100 DOI: 10.1172/Jci121526  0.301
2017 McGeough MD, Wree A, Inzaugarat ME, Haimovich A, Johnson CD, Peña CA, Goldbach-Mansky R, Broderick L, Feldstein AE, Hoffman HM. TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies. The Journal of Clinical Investigation. PMID 29130929 DOI: 10.1172/Jci90699  0.311
2017 Nakanishi H, Kawashima Y, Kurima K, Chae JJ, Ross AM, Pinto-Patarroyo G, Patel SK, Muskett JA, Ratay JS, Chattaraj P, Park YH, Grevich S, Brewer CC, Hoa M, Kim HJ, ... ... Broderick L, et al. NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847925 DOI: 10.1073/Pnas.1702946114  0.329
2017 Kuemmerle-Deschner JB, Verma D, Endres T, Broderick L, de Jesus AA, Hofer F, Blank N, Krause K, Rietschel C, Horneff G, Aksentijevich I, Lohse P, Goldbach-Mansky R, Hoffman HM, Benseler SM. Clinical and molecular phenotypes of low-penetrance variants in NLRP3: Diagnostic and therapeutic challenges. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28692792 DOI: 10.1002/Art.40208  0.31
2017 Radhakrishna SM, Grimm A, Broderick L. Novel mutation identified in severe early-onset tumor necrosis factor receptor-associated periodic syndrome: a case report. Bmc Pediatrics. 17: 108. PMID 28427379 DOI: 10.1186/S12887-017-0856-2  0.374
2015 Qu C, Bonar SL, Hickman-Brecks CL, Abu-Amer S, McGeough MD, Peña CA, Broderick L, Yang C, Grimston SK, Kading J, Abu-Amer Y, Novack DV, Hoffman HM, Civitelli R, Mbalaviele G. NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1269-79. PMID 25477279 DOI: 10.1096/Fj.14-264804  0.31
2015 Broderick L, De Nardo D, Franklin BS, Hoffman HM, Latz E. The inflammasomes and autoinflammatory syndromes. Annual Review of Pathology. 10: 395-424. PMID 25423351 DOI: 10.1146/Annurev-Pathol-012414-040431  0.323
2013 Brydges SD, Broderick L, McGeough MD, Pena CA, Mueller JL, Hoffman HM. Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies. The Journal of Clinical Investigation. 123: 4695-705. PMID 24084736 DOI: 10.1172/Jci71543  0.316
2013 Broderick L, Brydges S, McGeough, Pena C, Mueller J, Hoffman H. OR11-004 - IL-1, IL-18 and cell death in NLRP3 driven disease Pediatric Rheumatology. 11: 1-1. DOI: 10.1186/1546-0096-11-S1-A193  0.31
2007 Nazareth MR, Broderick L, Simpson-Abelson MR, Kelleher RJ, Yokota SJ, Bankert RB. Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 5552-62. PMID 17442937 DOI: 10.4049/Jimmunol.178.9.5552  0.652
2007 Nazareth MR, Broderick L, Simpson-Abelson MR, Kelleher RJ, Yokota SJ, Bankert RB. Response to comment on "Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells" Journal of Immunology. 179: 733. DOI: 10.4049/Jimmunol.179.2.733  0.644
2007 Broderick L, Bankert R. IL-12/TGF-β1 Regulation of TCR Signal Transduction in Human Memory T Cells Associated with Malignant and Non-malignant Chronic Inflammatory Microenvironments Journal of Allergy and Clinical Immunology. 119: S92. DOI: 10.1016/j.jaci.2006.11.389  0.568
2006 Broderick L, Bankert RB. Membrane-associated TGF-beta1 inhibits human memory T cell signaling in malignant and nonmalignant inflammatory microenvironments. Journal of Immunology (Baltimore, Md. : 1950). 177: 3082-8. PMID 16920945 DOI: 10.4049/Jimmunol.177.5.3082  0.622
2006 Broderick L, Bankert RB. Memory T cells in human tumor and chronic inflammatory microenvironments: sleeping beauties re-awakened by a cytokine kiss. Immunological Investigations. 35: 419-36. PMID 16916760 DOI: 10.1080/08820130600755066  0.692
2006 Bernstein JM, Broderick L, Parsons RR, Bankert RB. Human nasal polyp microenvironment maintained in viable and functional states as xenografts in SCID mice. The Annals of Otology, Rhinology, and Laryngology. 115: 65-73. PMID 16466102 DOI: 10.1177/000348940611500110  0.532
2006 Broderick L, Brooks SP, Takita H, Baer AN, Bernstein JM, Bankert RB. IL-12 reverses anergy to T cell receptor triggering in human lung tumor-associated memory T cells. Clinical Immunology (Orlando, Fla.). 118: 159-69. PMID 16271513 DOI: 10.1016/J.Clim.2005.09.008  0.638
2005 Broderick L, Yokota SJ, Reineke J, Mathiowitz E, Stewart CC, Barcos M, Kelleher RJ, Bankert RB. Human CD4+ effector memory T cells persisting in the microenvironment of lung cancer xenografts are activated by local delivery of IL-12 to proliferate, produce IFN-gamma, and eradicate tumor cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 898-906. PMID 15634912 DOI: 10.4049/Jimmunol.174.2.898  0.72
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