| Year |
Citation |
Score |
| 2020 |
Mattelaer HP, Van Hool AS, de Jong F, Van der Auweraer M, Van Meervelt L, Dehaen W, Herdewijn P. New metal-free route towards imidazole substituted uridine. European Journal of Organic Chemistry. PMID 32837299 DOI: 10.1002/Ejoc.202000563 |
0.362 |
|
| 2020 |
Li Q, Groaz E, Persoons L, Daelemans D, Herdewijn P. Synthesis and Antitumor Activity of C-7-Alkynylated and Arylated Pyrrolotriazine C-Ribonucleosides. Acs Medicinal Chemistry Letters. 11: 1605-1610. PMID 32832030 DOI: 10.1021/Acsmedchemlett.0C00269 |
0.343 |
|
| 2020 |
Luo M, Groaz E, Snoeck R, Andrei G, Herdewijn P. Amidate Prodrugs of -2-Alkylated Pyrimidine Acyclic Nucleosides Display Potent Anti-Herpesvirus Activity. Acs Medicinal Chemistry Letters. 11: 1410-1415. PMID 32676147 DOI: 10.1021/Acsmedchemlett.0C00090 |
0.386 |
|
| 2020 |
De Fenza M, Eremeeva E, Troisi R, Yang H, Esposito A, Sica F, Herdewijn P, D'Alonzo D, Guaragna A. Structure-Activity Relationship Study of a Potent α-Thrombin Binding Aptamer Incorporating Hexitol Nucleotides. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32363791 DOI: 10.1002/Chem.202001504 |
0.304 |
|
| 2020 |
Li Q, Groaz E, Rocha-Pereira J, Neyts J, Herdewijn P. Anti-norovirus activity of C7-modified 4-amino-pyrrolo[2,1-f][1,2,4]triazine C-nucleosides. European Journal of Medicinal Chemistry. 195: 112198. PMID 32294613 DOI: 10.1016/J.Ejmech.2020.112198 |
0.355 |
|
| 2020 |
Kumar P, Degaonkar R, Guenther DC, Abramov M, Schepers G, Capobianco M, Jiang Y, Harp J, Kaittanis C, Janas MM, Castoreno A, Zlatev I, Schlegel MK, Herdewijn P, Egli M, et al. Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc-siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5'-exonuclease. Nucleic Acids Research. PMID 32170309 DOI: 10.1093/Nar/Gkaa125 |
0.367 |
|
| 2020 |
Papastavrou N, Bande O, Marlière P, Groaz E, Herdewijn P. Vitamin-guanosine monophosphate conjugates for in vitro transcription priming. Chemical Communications (Cambridge, England). PMID 32025667 DOI: 10.1039/C9Cc09427J |
0.325 |
|
| 2020 |
Ji S, Wang S, Wang H, Gao Y, Xu W, Huo X, Herdewijn P, Liu F. Synthesis and Antiviral Evaluation of 3'‐C‐Hydroxymethyl‐3'‐O‐Phosphonomethyl‐β‐D‐5'‐deoxyxylose Nucleosides European Journal of Organic Chemistry. 2020: 4995-5002. DOI: 10.1002/Ejoc.202000831 |
0.329 |
|
| 2019 |
Nguyen H, Abramov M, Eremeeva E, Herdewijn P. In vivo Expression of Genetic Information from Phosphoramidate-DNA. Chembiochem : a European Journal of Chemical Biology. PMID 31868979 DOI: 10.1002/Cbic.201900712 |
0.313 |
|
| 2019 |
Li Q, Persoons L, Daelemans D, Herdewijn P. Iron/Copper Co-Catalyzed Cross-Coupling Reaction for the Synthesis of 6-Substituted 7-Deazapurines and the Corresponding Nucleosides. The Journal of Organic Chemistry. PMID 31858795 DOI: 10.1021/Acs.Joc.9B02414 |
0.35 |
|
| 2019 |
Eremeeva E, Herdewijn P. Reprint of: Non Canonical Genetic Material. Current Opinion in Biotechnology. 60: 259-267. PMID 31759815 DOI: 10.1016/J.Copbio.2019.11.009 |
0.324 |
|
| 2019 |
Martinez-Gualda B, Pu SY, Froeyen M, Herdewijn P, Einav S, De Jonghe S. Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase. Bioorganic & Medicinal Chemistry. 115188. PMID 31757682 DOI: 10.1016/J.Bmc.2019.115188 |
0.321 |
|
| 2019 |
Vanmeert M, Razzokov J, Mirza MU, Weeks SD, Schepers G, Bogaerts A, Rozenski J, Froeyen M, Herdewijn P, Pinheiro VB, Lescrinier E. Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins. Nucleic Acids Research. PMID 31713624 DOI: 10.1093/Nar/Gkz1090 |
0.317 |
|
| 2019 |
Leonczak P, Srivastava P, Bande O, Schepers G, Lescrinier E, Herdewijn P. -Glycosylated 8-Azapurine and Methylated Purine Nucleobases: Synthesis and Study of Base Pairing Properties. The Journal of Organic Chemistry. PMID 31617362 DOI: 10.1021/Acs.Joc.9B01576 |
0.31 |
|
| 2019 |
Mikhailov SN, Drenichev MS, Oslovsky VE, Kulikova IV, Herdewijn P. Synthesis of Poly(ADP-ribose) Monomer Containing 2'-O-α-D-Ribofuranosyl Adenosine. Current Protocols in Nucleic Acid Chemistry. 78: e92. PMID 31529780 DOI: 10.1002/Cpnc.92 |
0.321 |
|
| 2019 |
Luo M, Groaz E, Froeyen M, Pezo V, Jaziri F, Leonczak P, Schepers G, Rozenski J, Marlière P, Herdewijn P. Invading Escherichia coli Genetics with a Xenobiotic Nucleic Acid Carrying an Acyclic Phosphonate Backbone (ZNA). Journal of the American Chemical Society. PMID 31251601 DOI: 10.1021/Jacs.9B04714 |
0.325 |
|
| 2019 |
Verdonck S, Pu SY, Sorrell FJ, Elkins JM, Froeyen M, Gao LJ, Prugar LI, Dorosky DE, Brannan JM, Barouch-Bentov R, Knapp S, Dye JM, Herdewijn P, Einav S, De Jonghe S. Synthesis and structure-activity relationships of 3,5-disubstituted-pyrrolo[2,3- b]pyridines as inhibitors of adaptor associated kinase 1 (AAK1) with antiviral activity. Journal of Medicinal Chemistry. PMID 31136173 DOI: 10.1021/Acs.Jmedchem.9B00136 |
0.306 |
|
| 2019 |
Li X, Dumbre SG, Lescrinier E, Groaz E, Herdewijn P. Synthesis and Conformation of Pentopyranoside Nucleoside Phosphonates. The Journal of Organic Chemistry. PMID 31046278 DOI: 10.1021/Acs.Joc.8B03178 |
0.397 |
|
| 2019 |
Nie P, Groaz E, Daelemans D, Herdewijn P. Xylo-C-nucleosides with a pyrrolo[2,1-f][1,2,4]triazin-4-amine heterocyclic base: Synthesis and antiproliferative properties. Bioorganic & Medicinal Chemistry Letters. PMID 31005446 DOI: 10.1016/J.Bmcl.2019.04.023 |
0.337 |
|
| 2019 |
Modranka J, Li J, Parchina A, Vanmeert M, Dumbre S, Salman M, Myllykallio H, Becker HF, Vanhoutte R, Margamuljana L, Nguyen H, Abu El Asrar R, Rozenski J, Herdewijn P, Dejonghe S, et al. Synthesis and structure-activity relationship studies of benzo[b][1,4]oxazin-3(4H)-one analogues as inhibitors of mycobacterial thymidylate synthase X. Chemmedchem. PMID 30702807 DOI: 10.1002/Cmdc.201800739 |
0.322 |
|
| 2019 |
Renders M, Dumbre S, Abramov M, Kestemont D, Margamuljana L, Largy E, Cozens C, Vandenameele J, Pinheiro VB, Toye D, Frère JM, Herdewijn P. Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases. Nucleic Acids Research. PMID 30698800 DOI: 10.1093/Nar/Gkz008 |
0.359 |
|
| 2019 |
Kestemont D, Herdewijn P, Renders M. Enzymatic Synthesis of Backbone-Modified Oligonucleotides Using T4 DNA Ligase. Current Protocols in Chemical Biology. e62. PMID 30688416 DOI: 10.1002/Cpch.62 |
0.35 |
|
| 2019 |
Röthlisberger P, Levi-Acobas F, Sarac I, Marlière P, Herdewijn P, Hollenstein M. Towards the enzymatic formation of artificial metal base pairs with a carboxy-imidazole-modified nucleotide. Journal of Inorganic Biochemistry. 191: 154-163. PMID 30529723 DOI: 10.1016/J.Jinorgbio.2018.11.009 |
0.324 |
|
| 2019 |
Wouters R, Pu SY, Froeyen M, Lescrinier E, Einav S, Herdewijn P, De Jonghe S. Cyclin G-associated kinase (GAK) affinity and antiviral activity studies of a series of 3-C-substituted isothiazolo[4,3-b]pyridines. European Journal of Medicinal Chemistry. 163: 256-265. PMID 30529544 DOI: 10.1016/J.Ejmech.2018.11.065 |
0.335 |
|
| 2019 |
Li Q, Groaz E, Herdewijn P. Synthesis of tetradialdose phosphonate nucleosides as mimics of L-nucleotides Tetrahedron. 75: 130497. DOI: 10.1016/J.Tet.2019.130497 |
0.413 |
|
| 2019 |
Jabgunde AM, Patil RS, De S, Lescrinier E, Jonghe SD, Beigelman L, Herdewijn P. Synthesis of 3′-fluoro-4′-amino-hexitol nucleosides with a pyrimidine nucleobase as building blocks for oligonucleotides Tetrahedron. 75: 1107-1114. DOI: 10.1016/J.Tet.2019.01.026 |
0.402 |
|
| 2019 |
Nie P, Groaz E, Herdewijn P. Synthesis of a Threosyl‐C‐nucleoside Phosphonate European Journal of Organic Chemistry. 2019: 6666-6672. DOI: 10.1002/Ejoc.201901200 |
0.345 |
|
| 2018 |
Eremeeva E, Herdewijn P. Non canonical genetic material. Current Opinion in Biotechnology. 57: 25-33. PMID 30554069 DOI: 10.1016/J.Copbio.2018.12.001 |
0.324 |
|
| 2018 |
Wouters R, Tian J, Herdewijn P, De Jonghe S. A scaffold hopping strategy towards the identification of inhibitors of cyclin G associated kinase. Chemmedchem. PMID 30548533 DOI: 10.1002/Cmdc.201800690 |
0.302 |
|
| 2018 |
De S, Jabgunde AM, Patil RS, De Jonghe S, Beigelman L, Herdewijn P. Synthesis of Protected Amino Hexitol Nucleosides as Building Blocks for Oligonucleotide Synthesis. The Journal of Organic Chemistry. PMID 30525618 DOI: 10.1021/Acs.Joc.8B02444 |
0.416 |
|
| 2018 |
Mutschler H, Taylor AI, Porebski BT, Lightowlers A, Houlihan G, Abramov M, Herdewijn P, Holliger P. Random-sequence genetic oligomer pools display an innate potential for ligation and recombination. Elife. 7. PMID 30461419 DOI: 10.7554/Elife.43022 |
0.302 |
|
| 2018 |
Luo M, Groaz E, De Jonghe S, Schols D, Herdewijn P. Synthesis and anti-HIV activity of guanine modified fluorinated acyclic nucleoside phosphonates derivatives. Chemistry & Biodiversity. PMID 30431702 DOI: 10.1002/Cbdv.201800532 |
0.394 |
|
| 2018 |
Bauwens B, Rozenski J, Herdewijn P, Robben J. A single amino acid substitution in Therminator DNA polymerase increases incorporation efficiency of deoxyxylonucleotides. Chembiochem : a European Journal of Chemical Biology. PMID 30204290 DOI: 10.1002/Cbic.201800411 |
0.363 |
|
| 2018 |
Eremeeva E, Herdewijn P. PCR Amplification of Base-Modified DNA. Current Protocols in Chemical Biology. 10: 18-48. PMID 30040232 DOI: 10.1002/Cpch.33 |
0.338 |
|
| 2018 |
Pu SY, Wouters R, Schor S, Rozenski J, Barouch-Bentov R, Prugar LI, Obrien CM, Brannan JM, Dye JM, Herdewijn P, De Jonghe S, Einav S. Optimization of isothiazolo[4,3-b]pyridine-based inhibitors of cyclin G associated kinase (GAK) with broad-spectrum antiviral activity. Journal of Medicinal Chemistry. PMID 29953812 DOI: 10.1021/Acs.Jmedchem.8B00613 |
0.317 |
|
| 2018 |
Reuberson J, Horsley H, Franklin RJ, Ford D, Neuss J, Brookings D, Huang Q, Vanderhoydonck B, Gao LJ, Jang M, Herdewijn P, Ghawalkar A, Fallah-Arani F, Khan A, Henshall J, et al. Discovery of a potent, orally bioavailable PI4KIIIβ inhibitor (UCB9608) able to significantly prolong allogeneic organ engraftment in vivo. Journal of Medicinal Chemistry. PMID 29952567 DOI: 10.1021/Acs.Jmedchem.8B00521 |
0.319 |
|
| 2018 |
da Paixao Soares F, Groaz E, Herdewijn P. Phosphorus Pentachloride Promoted -Dichlorination of 2'- and 3'-Deoxynucleosides. Molecules (Basel, Switzerland). 23. PMID 29914115 DOI: 10.3390/Molecules23061457 |
0.305 |
|
| 2018 |
Jabgunde AM, Jaziri F, Bande O, Froeyen M, Abramov M, Nguyen H, Schepers G, Lescrinier E, Pinheiro VB, Pezo V, Marlière P, Herdewijn P. Methylated nucleobases: Synthesis and evaluation for base pairing in vitro and in vivo. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29883012 DOI: 10.1002/Chem.201802304 |
0.327 |
|
| 2018 |
Liu C, Cozens C, Jaziri F, Rozenski J, Maréchal A, Dumbre SG, Pezo V, Marliere P, Pinheiro VB, Groaz E, Herdewijn P. Phosphonomethyl Oligonucleotides as Backbone Modified Artifi-cial Genetic Polymers. Journal of the American Chemical Society. PMID 29722977 DOI: 10.1021/Jacs.8B03447 |
0.325 |
|
| 2018 |
Luo M, Groaz E, De Jonghe S, Snoeck R, Andrei G, Herdewijn P. Amidate Prodrugs of Cyclic 9-()-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine with Potent Anti-Herpesvirus Activity. Acs Medicinal Chemistry Letters. 9: 381-385. PMID 29670705 DOI: 10.1021/Acsmedchemlett.8B00079 |
0.342 |
|
| 2018 |
Wang M, Srivastava P, Liu C, Snoeck R, Andrei G, De Jonghe S, Herdewijn P. Synthesis and antiviral evaluation of cyclopentyl nucleoside phosphonates. European Journal of Medicinal Chemistry. 150: 616-625. PMID 29550734 DOI: 10.1016/J.Ejmech.2018.03.008 |
0.338 |
|
| 2018 |
Nie P, Groaz E, De Jonghe S, Lescrinier E, Herdewijn P. Synthesis of a C-Nucleoside Phosphonate by Base-Promoted Epimerization. Organic Letters. PMID 29388776 DOI: 10.1021/Acs.Orglett.8B00123 |
0.342 |
|
| 2018 |
Gasse C, Zaarour M, Noppen S, Abramov M, Marlière P, Liekens S, De Strooper B, Herdewijn P. Modulation of BACE1 activity by chemically modified aptamers. Chembiochem : a European Journal of Chemical Biology. PMID 29327496 DOI: 10.1002/Cbic.201700461 |
0.321 |
|
| 2018 |
Röthlisberger P, Levi-Acobas F, Sarac I, Ricoux R, Mahy J, Herdewijn P, Marlière P, Hollenstein M. Incorporation of a minimal nucleotide into DNA Tetrahedron Letters. 59: 4241-4244. DOI: 10.1016/J.Tetlet.2018.10.036 |
0.306 |
|
| 2018 |
Nie P, Groaz E, Jonghe SD, Andrei G, Herdewijn P. Synthesis of a 3′‐Deoxy‐C‐Nucleoside Phosphonate Bearing 9‐Deazaadenine as Base Moiety European Journal of Organic Chemistry. 2018: 6657-6664. DOI: 10.1002/Ejoc.201800889 |
0.374 |
|
| 2017 |
Plebanek E, Lescrinier E, Andrei G, Snoeck R, Herdewijn P, De Jonghe S. Emimycin and its nucleoside derivatives: Synthesis and antiviral activity. European Journal of Medicinal Chemistry. 144: 93-103. PMID 29268134 DOI: 10.1016/J.Ejmech.2017.12.018 |
0.371 |
|
| 2017 |
Tian J, Vandermosten L, Peigneur S, Moreels L, Rozenski J, Tytgat J, Herdewijn P, Van den Steen PE, De Jonghe S. Astemizole analogues with reduced hERG inhibition as potent antimalarial compounds. Bioorganic & Medicinal Chemistry. PMID 29042223 DOI: 10.1016/J.Bmc.2017.10.004 |
0.315 |
|
| 2017 |
Abu El Asrar R, Margamuljana L, Abramov M, Bande O, Agnello S, Jang M, Herdewijn P. Enzymatic incorporation of modified purine nucleotides in DNA. Chembiochem : a European Journal of Chemical Biology. PMID 29024251 DOI: 10.1002/Cbic.201700393 |
0.368 |
|
| 2017 |
De S, De Jonghe S, Herdewijn P. Synthesis of a 3'-Fluoro-3'-deoxytetrose Adenine Phosphonate. The Journal of Organic Chemistry. PMID 28849659 DOI: 10.1021/Acs.Joc.7B01482 |
0.38 |
|
| 2017 |
Ramaswamy A, Smyrnova D, Froeyen M, Maiti M, Herdewijn P, Ceulemans A. Molecular Dynamics of double stranded Xylo Nucleic Acid (XyloNA). Journal of Chemical Theory and Computation. PMID 28742346 DOI: 10.1021/Acs.Jctc.7B00309 |
0.334 |
|
| 2017 |
Luo M, Groaz E, Andrei G, Snoeck R, Kalkeri R, Ptak RG, Hartman T, Buckheit RW, Schols D, De Jonghe S, Herdewijn P. Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs. Journal of Medicinal Chemistry. PMID 28682067 DOI: 10.1021/Acs.Jmedchem.7B00416 |
0.343 |
|
| 2017 |
Liu C, Dumbre SG, Pannecouque C, Korba B, De Jonghe S, Herdewijn P. Synthesis and antiviral evaluation of base-modified deoxythreosyl nucleoside phosphonates. Organic & Biomolecular Chemistry. PMID 28628181 DOI: 10.1039/C7Ob01265A |
0.302 |
|
| 2017 |
Eremeeva E, Abramov M, Margamuljana L, Herdewijn P. Base-modified nucleic acids as a powerful tool for synthetic biology and biotechnology. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28513881 DOI: 10.1002/Chem.201700679 |
0.318 |
|
| 2017 |
Röthlisberger P, Levi-Acobas F, Sarac I, Marlière P, Herdewijn P, Hollenstein M. On the enzymatic incorporation of an imidazole nucleotide into DNA. Organic & Biomolecular Chemistry. PMID 28485736 DOI: 10.1039/C7Ob00858A |
0.317 |
|
| 2017 |
Eremeeva E, Abramov M, Marlière P, Herdewijn P. The 5-chlorouracil:7-deazaadenine base pair as an alternative to the dT:dA base pair Organic and Biomolecular Chemistry. 15: 168-176. PMID 27918055 DOI: 10.1039/C6Ob02274J |
0.359 |
|
| 2016 |
Bande O, Braddick D, Agnello S, Jang M, Pezo V, Schepers G, Rozenski J, Lescrinier E, Marlière P, Herdewijn P. Base pairing involving artificial bases and . Chemical Science. 7: 995-1010. PMID 29896368 DOI: 10.1039/C5Sc03474D |
0.352 |
|
| 2016 |
Gao LJ, Jonghe S, Herdewijn P. Synthesis of a Nucleobase-Modified ProTide Library. Organic Letters. PMID 27791384 DOI: 10.1021/Acs.Orglett.6B02764 |
0.365 |
|
| 2016 |
Le BT, Chen S, Abramov M, Herdewijn P, Veedu RN. Evaluation of anhydrohexitol nucleic acid, cyclohexenyl nucleic acid and d-altritol nucleic acid-modified 2'-O-methyl RNA mixmer antisense oligonucleotides for exon skipping in vitro. Chemical Communications (Cambridge, England). PMID 27790668 DOI: 10.1039/C6Cc07447B |
0.336 |
|
| 2016 |
Liu C, Dumbre SG, Pannecouque C, Huang C, Ptak RG, Murray MG, De Jonghe S, Herdewijn P. Amidate Prodrugs of Deoxythreosyl Nucleoside Phosphonates as Dual Inhibitors of HIV and HBV Replication. Journal of Medicinal Chemistry. PMID 27748590 DOI: 10.1021/Acs.Jmedchem.6B01260 |
0.343 |
|
| 2016 |
Lee SY, Perotti A, De Jonghe S, Herdewijn P, Hanck T, Müller CE. Thiazolo[3,2-a]benzimidazol-3(2H)-one derivatives: Structure-activity relationships of selective nucleotide pyrophosphatase/phosphodiesterase1 (NPP1) inhibitors. Bioorganic & Medicinal Chemistry. PMID 27265686 DOI: 10.1016/J.Bmc.2016.05.046 |
0.315 |
|
| 2016 |
Eremeeva E, Abramov M, Margamuljana L, Rozenski J, Pezo V, Marlière P, Herdewijn P. Chemical Morphing of DNA Containing Four Noncanonical Bases. Angewandte Chemie (International Ed. in English). PMID 27159019 DOI: 10.1002/Anie.201601529 |
0.347 |
|
| 2016 |
De S, Groaz E, Margamuljana L, Herdewijn P. Syntheses of 5'-Nucleoside Monophosphate Derivatives with Unique Aminal, Hemiaminal, and Hemithioaminal Functionalities: A New Class of 5'-Peptidyl Nucleotides. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27136602 DOI: 10.1002/Chem.201600721 |
0.385 |
|
| 2016 |
Gao LJ, De Jonghe S, Daelemans D, Herdewijn P. l-Aspartic and l-glutamic acid ester-based ProTides of anticancer nucleosides: Synthesis and antitumoral evaluation. Bioorganic & Medicinal Chemistry Letters. 26: 2142-6. PMID 27032331 DOI: 10.1016/J.Bmcl.2016.03.076 |
0.331 |
|
| 2016 |
Froeyen M, Abu El Asrar R, Abramov M, Herdewijn P. Molecular simulation of cyclohexanyl nucleic acid (CNA) duplexes with CNA, DNA and RNA and CNA triloop and tetraloop hairpin structures. Bioorganic & Medicinal Chemistry. 24: 1778-85. PMID 26968651 DOI: 10.1016/J.Bmc.2016.03.007 |
0.36 |
|
| 2016 |
Exner MP, Köhling S, Rivollier J, Gosling S, Srivastava P, Palyancheva ZI, Herdewijn P, Heck MP, Rademann J, Budisa N. Incorporation of Amino Acids with Long-Chain Terminal Olefins into Proteins. Molecules (Basel, Switzerland). 21. PMID 26938510 DOI: 10.3390/Molecules21030287 |
0.322 |
|
| 2015 |
Li J, Kovackova S, Pu S, Rozenski J, De Jonghe S, Einav S, Herdewijn P. Isothiazolo[4,3-b]pyridines as inhibitors of cyclin G associated kinase : synthesis, structure-activity relationship studies and antiviral activity. Medchemcomm. 6: 1666-1672. PMID 26925208 DOI: 10.1039/C5Md00229J |
0.31 |
|
| 2015 |
Toti K, Renders M, Groaz E, Herdewijn P, Van Calenbergh S. Nucleosides with Transposed Base or 4'-Hydroxymethyl Moieties and Their Corresponding Oligonucleotides. Chemical Reviews. 115: 13484-525. PMID 26655745 DOI: 10.1021/Acs.Chemrev.5B00545 |
0.403 |
|
| 2015 |
Groaz E, Herdewijn P. Nucleoside Phosphate-Conjugates Come of Age: Catalytic Transformation, Polymerase Recognition and Antiviral Properties. Current Medicinal Chemistry. 22: 3980-90. PMID 26597062 DOI: 10.2174/092986732234151119155207 |
0.32 |
|
| 2015 |
Paolella C, D'Alonzo D, Schepers G, Van Aerschot A, Di Fabio G, Palumbo G, Herdewijn P, Guaragna A. Oligonucleotides containing a ribo-configured cyclohexanyl nucleoside: probing the role of sugar conformation in base pairing selectivity. Organic & Biomolecular Chemistry. 13: 10041-9. PMID 26293202 DOI: 10.1039/C5Ob01449B |
0.342 |
|
| 2015 |
Dyubankova N, Froeyen M, Abramov M, Mattelaer HP, Herdewijn P, Lescrinier E. NMR study on the interaction of the conserved CREX 'stem-loop' in the Hepatitis E virus genome with a naphthyridine-based ligand. Organic & Biomolecular Chemistry. 13: 9665-72. PMID 26264660 DOI: 10.1039/C5Ob01381J |
0.31 |
|
| 2015 |
Srivastava P, Abou El Asrar R, Knies C, Abramov M, Froeyen M, Rozenski J, Rosemeyer H, Herdewijn P. Achiral, acyclic nucleic acids: synthesis and biophysical studies of a possible prebiotic polymer. Organic & Biomolecular Chemistry. 13: 9249-60. PMID 26228702 DOI: 10.1039/C5Ob00898K |
0.322 |
|
| 2015 |
da Paixão Soares F, Groaz E, Lescrinier E, Neyts J, Leyssen P, Herdewijn P. NMR-based conformational analysis of 2',6-disubstituted uridines and antiviral evaluation of new phosphoramidate prodrugs. Bioorganic & Medicinal Chemistry. 23: 5809-15. PMID 26210159 DOI: 10.1016/J.Bmc.2015.07.003 |
0.345 |
|
| 2015 |
Maiti M, Maiti M, Knies C, Dumbre S, Lescrinier E, Rosemeyer H, Ceulemans A, Herdewijn P. Xylonucleic acid: synthesis, structure, and orthogonal pairing properties. Nucleic Acids Research. 43: 7189-200. PMID 26175047 DOI: 10.1093/Nar/Gkv719 |
0.362 |
|
| 2015 |
Liu F, Liu Y, Xu RG, Dai G, Zhao LX, Wang Y, Liu HM, Liu FW, Pannecouque C, Herdewijn P. Synthesis and in vitro antiviral activities of [(dihydrofuran-2-yl)oxy]methyl-phosphonate nucleosides with 2-substituted adenine as base. Chemistry & Biodiversity. 12: 813-22. PMID 26010668 DOI: 10.1002/Cbdv.201400418 |
0.409 |
|
| 2015 |
D'Alonzo D, Froeyen M, Schepers G, Di Fabio G, Van Aerschot A, Herdewijn P, Palumbo G, Guaragna A. 1',5'-Anhydro-L-ribo-hexitol Adenine Nucleic Acids (α-L-HNA-A): Synthesis and Chiral Selection Properties in the Mirror Image World. The Journal of Organic Chemistry. 80: 5014-22. PMID 25853790 DOI: 10.1021/Acs.Joc.5B00406 |
0.322 |
|
| 2015 |
Maiti M, Maiti M, Rozenski J, De Jonghe S, Herdewijn P. Aspartic acid based nucleoside phosphoramidate prodrugs as potent inhibitors of hepatitis C virus replication. Organic & Biomolecular Chemistry. 13: 5158-74. PMID 25849139 DOI: 10.1039/C5Ob00427F |
0.336 |
|
| 2015 |
Kovackova S, Chang L, Bekerman E, Neveu G, Barouch-Bentov R, Chaikuad A, Heroven C, Šála M, De Jonghe S, Knapp S, Einav S, Herdewijn P. Selective Inhibitors of Cyclin G Associated Kinase (GAK) as Anti-Hepatitis C Agents. Journal of Medicinal Chemistry. 58: 3393-410. PMID 25822739 DOI: 10.1021/Jm501759M |
0.307 |
|
| 2015 |
Dyubankova N, Sochacka E, Kraszewska K, Nawrot B, Herdewijn P, Lescrinier E. Contribution of dihydrouridine in folding of the D-arm in tRNA. Organic and Biomolecular Chemistry. 13: 4960-4966. PMID 25815904 DOI: 10.1039/C5Ob00164A |
0.307 |
|
| 2015 |
Delespaul W, Peeters Y, Herdewijn P, Robben J. A novel helper phage for HaloTag-mediated co-display of enzyme and substrate on phage. Biochemical and Biophysical Research Communications. 460: 245-9. PMID 25772618 DOI: 10.1016/J.Bbrc.2015.03.019 |
0.31 |
|
| 2015 |
De S, Groaz E, Margamuljana L, Abramov M, Marlière P, Herdewijn P. Sulfonate derived phosphoramidates as active intermediates in the enzymatic primer-extension of DNA. Organic & Biomolecular Chemistry. 13: 3950-62. PMID 25719514 DOI: 10.1039/C5Ob00157A |
0.354 |
|
| 2015 |
Bande O, Abu El Asrar R, Braddick D, Dumbre S, Pezo V, Schepers G, Pinheiro VB, Lescrinier E, Holliger P, Marlière P, Herdewijn P. Isoguanine and 5-methyl-isocytosine bases, in vitro and in vivo. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 5009-22. PMID 25684598 DOI: 10.1002/Chem.201406392 |
0.345 |
|
| 2015 |
Taylor AI, Pinheiro VB, Smola MJ, Morgunov AS, Peak-Chew S, Cozens C, Weeks KM, Herdewijn P, Holliger P. Catalysts from synthetic genetic polymers. Nature. 518: 427-30. PMID 25470036 DOI: 10.1038/Nature13982 |
0.318 |
|
| 2014 |
Gangadhara KL, Srivastava P, Rozenski J, Mattelaer HP, Leen V, Dehaen W, Hofkens J, Lescrinier E, Herdewijn P. Design and synthesis of nucleolipids as possible activated precursors for oligomer formation via intramolecular catalysis: stability study and supramolecular organization. Journal of Systems Chemistry. 5: 5. PMID 25558290 DOI: 10.1186/S13322-014-0005-3 |
0.336 |
|
| 2014 |
Chang L, Lee SY, Leonczak P, Rozenski J, De Jonghe S, Hanck T, Müller CE, Herdewijn P. Imidazopyridine- and purine-thioacetamide derivatives: potent inhibitors of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1). Journal of Medicinal Chemistry. 57: 10080-100. PMID 25372276 DOI: 10.1021/Jm501434Y |
0.329 |
|
| 2014 |
Markad PR, Sonawane DP, Ghosh S, Chopade BA, Kumbhar N, Louat T, Herman J, Waer M, Herdewijn P, Dhavale DD. γ-Hydroxyethyl piperidine iminosugar and N-alkylated derivatives: A study of their activity as glycosidase inhibitors and as immunosuppressive agents Bioorganic and Medicinal Chemistry. 22: 5776-5782. PMID 25305010 DOI: 10.1016/J.Bmc.2014.09.034 |
0.36 |
|
| 2014 |
Gao LJ, Kovackova S, Sála M, Ramadori AT, De Jonghe S, Herdewijn P. Discovery of dual death-associated protein related apoptosis inducing protein kinase 1 and 2 inhibitors by a scaffold hopping approach. Journal of Medicinal Chemistry. 57: 7624-43. PMID 25178155 DOI: 10.1021/Jm5007929 |
0.312 |
|
| 2014 |
Pezo V, Schepers G, Lambertucci C, Marlière P, Herdewijn P. Probing ambiguous base-pairs by genetic transformation with XNA templates. Chembiochem : a European Journal of Chemical Biology. 15: 2255-8. PMID 25158283 DOI: 10.1002/Cbic.201402226 |
0.332 |
|
| 2014 |
Leonczak P, Gao LJ, Ramadori AT, Lescrinier E, Rozenski J, De Jonghe S, Herdewijn P. Synthesis and structure-activity relationship studies of 2-(1,3,4-oxadiazole-2(3H)-thione)-3-amino-5-arylthieno[2,3-b]pyridines as inhibitors of DRAK2. Chemmedchem. 9: 2587-601. PMID 25146684 DOI: 10.1002/Cmdc.201402234 |
0.346 |
|
| 2014 |
Bel Abed H, Mammoliti O, Bande O, Van Lommen G, Herdewijn P. Organophosphorus-catalyzed diaza-Wittig reaction: application to the synthesis of pyridazines. Organic & Biomolecular Chemistry. 12: 7159-66. PMID 25101802 DOI: 10.1039/C4Ob01201A |
0.308 |
|
| 2014 |
Kachare D, Song XP, Herdewijn P. Phospho-carboxylic anhydride of a homologated nucleoside leads to primer degradation in the presence of a polymerase. Bioorganic & Medicinal Chemistry Letters. 24: 2720-3. PMID 24813733 DOI: 10.1016/J.Bmcl.2014.04.042 |
0.361 |
|
| 2014 |
Toti KS, Derudas M, Pertusati F, Sinnaeve D, Van den Broeck F, Margamuljana L, Martins JC, Herdewijn P, Balzarini J, McGuigan C, Van Calenbergh S. Synthesis of an apionucleoside family and discovery of a prodrug with anti-HIV activity. The Journal of Organic Chemistry. 79: 5097-112. PMID 24804575 DOI: 10.1021/Jo500659E |
0.345 |
|
| 2014 |
Gangadhara KL, Lescrinier E, Pannecouque C, Herdewijn P. Hydroxy fatty acids for the delivery of dideoxynucleosides as anti-HIV agents. Bioorganic & Medicinal Chemistry Letters. 24: 817-20. PMID 24411122 DOI: 10.1016/J.Bmcl.2013.12.093 |
0.304 |
|
| 2014 |
De S, Groaz E, Maiti M, Pezo V, Marlière P, Herdewijn P. Synthesis of new biocarrier-nucleotide systems for cellular delivery in bacterial auxotrophic strains Tetrahedron. 70: 8843-8851. DOI: 10.1016/J.Tet.2014.09.096 |
0.338 |
|
| 2014 |
De S, Groaz E, Herdewijn P. Tailoring peptide-nucleotide conjugates (PNCs) for nucleotide delivery in bacterial cells European Journal of Organic Chemistry. 2014: 2322-2348. DOI: 10.1002/Ejoc.201301781 |
0.325 |
|
| 2014 |
Bande O, Herdewijn P. A convenient route for the synthesis of 3-deazaspongosine European Journal of Organic Chemistry. 2014: 231-236. DOI: 10.1002/Ejoc.201301283 |
0.39 |
|
| 2013 |
Moors SL, Herdewijn P, Robben J, Ceulemans A. Cooperative dynamics of a DNA polymerase replicating complex. Biochimica Et Biophysica Acta. 1834: 2554-63. PMID 24041502 DOI: 10.1016/J.Bbapap.2013.09.003 |
0.303 |
|
| 2013 |
Zhou J, Abramov M, Liu F, Amrane S, Bourdoncle A, Herdewijn P, Mergny JL. Effects of six-membered carbohydrate rings on structure, stability, and kinetics of G-quadruplexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 14719-25. PMID 24027098 DOI: 10.1002/Chem.201301743 |
0.306 |
|
| 2013 |
Bel Abed H, Mammoliti O, Bande O, Van Lommen G, Herdewijn P. Strategy for the synthesis of pyridazine heterocycles and their derivatives. The Journal of Organic Chemistry. 78: 7845-58. PMID 23947534 DOI: 10.1021/Jo400989Q |
0.38 |
|
| 2013 |
Parchina A, Froeyen M, Margamuljana L, Rozenski J, De Jonghe S, Briers Y, Lavigne R, Herdewijn P, Lescrinier E. Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue. Chemmedchem. 8: 1373-83. PMID 23836539 DOI: 10.1135/Css201414342 |
0.391 |
|
| 2013 |
Dumbre SG, Jang MY, Herdewijn P. Synthesis of α-L-threose nucleoside phosphonates via regioselective sugar protection. The Journal of Organic Chemistry. 78: 7137-44. PMID 23822647 DOI: 10.1021/Jo400907G |
0.301 |
|
| 2013 |
Pezo V, Liu FW, Abramov M, Froeyen M, Herdewijn P, Marlière P. Binary genetic cassettes for selecting XNA-templated DNA synthesis in vivo. Angewandte Chemie (International Ed. in English). 52: 8139-43. PMID 23804524 DOI: 10.1002/Anie.201303288 |
0.309 |
|
| 2013 |
D'Alonzo D, Amato J, Schepers G, Froeyen M, Van Aerschot A, Herdewijn P, Guaragna A. Enantiomeric selection properties of β-homoDNA: enhanced pairing for heterochiral complexes. Angewandte Chemie (International Ed. in English). 52: 6662-5. PMID 23670912 DOI: 10.1002/Anie.201301659 |
0.378 |
|
| 2013 |
Maiti M, Persoons L, Andrei G, Snoeck R, Balzarini J, Herdewijn P. Synthesis and anti-herpetic activity of phosphoramidate ProTides. Chemmedchem. 8: 985-93. PMID 23606629 DOI: 10.1002/Cmdc.201300035 |
0.345 |
|
| 2013 |
Jang MY, Song XP, Froeyen M, Marlière P, Lescrinier E, Rozenski J, Herdewijn P. A synthetic substrate of DNA polymerase deviating from the bases, sugar, and leaving group of canonical deoxynucleoside triphosphates. Chemistry & Biology. 20: 416-23. PMID 23521798 DOI: 10.1016/J.Chembiol.2013.02.010 |
0.355 |
|
| 2013 |
Baraguey C, Lescrinier E, Lavergne T, Debart F, Herdewijn P, Vasseur JJ. The biolabile 2'-O-pivaloyloxymethyl modification in an RNA helix: an NMR solution structure. Organic & Biomolecular Chemistry. 11: 2638-47. PMID 23455628 DOI: 10.1039/C3Ob27005J |
0.338 |
|
| 2013 |
Stella A, Van Belle K, De Jonghe S, Louat T, Herman J, Rozenski J, Waer M, Herdewijn P. Synthesis of a 2,4,6-trisubstituted 5-cyano-pyrimidine library and evaluation of its immunosuppressive activity in a Mixed Lymphocyte Reaction assay. Bioorganic & Medicinal Chemistry. 21: 1209-18. PMID 23347804 DOI: 10.1016/J.Bmc.2012.12.032 |
0.313 |
|
| 2013 |
Gao LJ, Schwed JS, Weizel L, De Jonghe S, Stark H, Herdewijn P. Synthesis and evaluation of novel ligands for the histamine H₄ receptor based on a pyrrolo[2,3-d]pyrimidine scaffold. Bioorganic & Medicinal Chemistry Letters. 23: 132-7. PMID 23218604 DOI: 10.1016/J.Bmcl.2012.10.139 |
0.336 |
|
| 2013 |
Attwater J, Tagami S, Kimoto M, Butler K, Kool ET, Wengel J, Herdewijn P, Hirao I, Holliger P. Chemical fidelity of an RNA polymerase ribozyme Chemical Science. 4: 2804-2814. DOI: 10.1039/C3Sc50574J |
0.343 |
|
| 2013 |
Abed HB, Bande O, Mammoliti O, Lommen GV, Herdewijn P. A novel and convenient strategy for the synthesis of phthalazines from an aryne precursor Tetrahedron Letters. 54: 7056-7058. DOI: 10.1016/J.Tetlet.2013.10.075 |
0.351 |
|
| 2013 |
Abed HB, Mammoliti O, Lommen GV, Herdewijn P. Simple approach to the synthesis of 3-fluoro pyrazolo[1,5-a]pyrimidine analogues Tetrahedron Letters. 54: 2612-2614. DOI: 10.1016/J.Tetlet.2013.03.015 |
0.392 |
|
| 2013 |
Stella A, De Jonghe S, Segers K, Herdewijn P. A short and straightforward approach towards 6-amino and 6-aminoalkyl thiazolo[4,5-c]pyridazines Tetrahedron Letters. 54: 830-833. DOI: 10.1016/J.Tetlet.2012.11.072 |
0.347 |
|
| 2013 |
Doboszewski B, Groaz E, Herdewijn P. Synthesis of phosphonoglycine backbone units for the development of phosphono peptide nucleic acids European Journal of Organic Chemistry. 4804-4815. DOI: 10.1002/Ejoc.201300523 |
0.358 |
|
| 2012 |
Song XP, Bouillon C, Lescrinier E, Herdewijn P. Dipeptides as leaving group in the enzyme-catalyzed DNA synthesis. Chemistry & Biodiversity. 9: 2685-700. PMID 23255441 DOI: 10.1002/Cbdv.201200261 |
0.36 |
|
| 2012 |
Yang S, Pannecouque C, Herdewijn P. Synthesis, and in vitro enzymatic and antiviral evaluation of d4T polyphosphate derivatives as chain terminators. Chemistry & Biodiversity. 9: 2186-94. PMID 23081918 DOI: 10.1002/Cbdv.201200250 |
0.317 |
|
| 2012 |
Giraut A, Abu El-Asrar R, Marlière P, Delarue M, Herdewijn P. 2'-Deoxyribonucleoside phosphoramidate triphosphate analogues as alternative substrates for E. coli polymerase III. Chembiochem : a European Journal of Chemical Biology. 13: 2439-44. PMID 23023962 DOI: 10.1002/Cbic.201200413 |
0.377 |
|
| 2012 |
Stevens M, Peigneur S, Dyubankova N, Lescrinier E, Herdewijn P, Tytgat J. Design of bioactive peptides from naturally occurring μ-conotoxin structures. The Journal of Biological Chemistry. 287: 31382-92. PMID 22773842 DOI: 10.1074/Jbc.M112.375733 |
0.315 |
|
| 2012 |
Herdewijn P, Marlière P. Redesigning the leaving group in nucleic acid polymerization Febs Letters. 586: 2049-2056. PMID 22710178 DOI: 10.1016/J.Febslet.2012.02.033 |
0.336 |
|
| 2012 |
Ovaere M, Sponer J, Sponer JE, Herdewijn P, Van Meervelt L. How does hydroxyl introduction influence the double helical structure: the stabilization of an altritol nucleic acid:ribonucleic acid duplex. Nucleic Acids Research. 40: 7573-83. PMID 22638588 DOI: 10.1093/Nar/Gks470 |
0.339 |
|
| 2012 |
Seth PP, Yu J, Jazayeri A, Pallan PS, Allerson CR, Østergaard ME, Liu F, Herdewijn P, Egli M, Swayze EE. Synthesis and antisense properties of fluoro cyclohexenyl nucleic acid (F-CeNA), a nuclease stable mimic of 2'-fluoro RNA. The Journal of Organic Chemistry. 77: 5074-85. PMID 22591005 DOI: 10.1021/Jo300594B |
0.374 |
|
| 2012 |
Dumbre S, Derouaux A, Lescrinier E, Piette A, Joris B, Terrak M, Herdewijn P. Synthesis of modified peptidoglycan precursor analogues for the inhibition of glycosyltransferase. Journal of the American Chemical Society. 134: 9343-51. PMID 22550974 DOI: 10.1021/Ja302099U |
0.33 |
|
| 2012 |
Kögler M, Busson R, De Jonghe S, Rozenski J, Van Belle K, Louat T, Munier-Lehmann H, Herdewijn P. Synthesis and evaluation of 6-aza-2'-deoxyuridine monophosphate analogs as inhibitors of thymidylate synthases, and as substrates or inhibitors of thymidine monophosphate kinase in Mycobacterium tuberculosis. Chemistry & Biodiversity. 9: 536-56. PMID 22422522 DOI: 10.1002/Cbdv.201100285 |
0.351 |
|
| 2012 |
Maiti M, Siegmund V, Abramov M, Lescrinier E, Rosemeyer H, Froeyen M, Ramaswamy A, Ceulemans A, Marx A, Herdewijn P. Solution structure and conformational dynamics of deoxyxylonucleic acids (dXNA): an orthogonal nucleic acid candidate. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 869-79. PMID 22180030 DOI: 10.1002/Chem.201102509 |
0.34 |
|
| 2012 |
Maiti M, Michielssens S, Dyubankova N, Maiti M, Lescrinier E, Ceulemans A, Herdewijn P. Influence of the nucleobase and anchimeric assistance of the carboxyl acid groups in the hydrolysis of amino acid nucleoside phosphoramidates. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 857-68. PMID 22173724 DOI: 10.1002/Chem.201102279 |
0.348 |
|
| 2012 |
Michielssens S, Maiti M, Maiti M, Dyubankova N, Herdewijn P, Ceulemans A. Reactivity of amino acid nucleoside phosphoramidates: a mechanistic quantum chemical study. The Journal of Physical Chemistry. A. 116: 644-52. PMID 22074558 DOI: 10.1021/Jp208795F |
0.323 |
|
| 2012 |
Yang S, Pannecouque C, Lescrinier E, Giraut A, Herdewijn P. Synthesis and in vitro enzymatic and antiviral evaluation of phosphoramidate d4T derivatives as chain terminators. Organic & Biomolecular Chemistry. 10: 146-53. PMID 22069085 DOI: 10.1039/C1Ob06214J |
0.302 |
|
| 2012 |
Abed HB, Mammoliti O, Lommen GV, Herdewijn P. A short and convenient strategy for the synthesis of pyridazines via Diaza–Wittig reaction Tetrahedron Letters. 53: 6489-6491. DOI: 10.1016/J.Tetlet.2012.09.059 |
0.357 |
|
| 2012 |
Kögler M, De Jonghe S, Herdewijn P. Synthesis of 6-aryl-2′-deoxyuridine nucleosides via a Liebeskind cross-coupling methodology Tetrahedron Letters. 53: 253-255. DOI: 10.1016/J.Tetlet.2011.11.036 |
0.343 |
|
| 2011 |
Yang S, Herdewijn P. Polymerase-dependent DNA synthesis from phosphoramidate-activated nucleotides. Nucleosides, Nucleotides & Nucleic Acids. 30: 597-608. PMID 21888550 DOI: 10.1080/15257770.2011.598491 |
0.374 |
|
| 2011 |
Song XP, Bouillon C, Lescrinier E, Herdewijn P. Iminodipropionic acid as the leaving group for DNA polymerization by HIV-1 reverse transcriptase. Chembiochem : a European Journal of Chemical Biology. 12: 1868-80. PMID 21714056 DOI: 10.1002/Cbic.201100160 |
0.362 |
|
| 2011 |
Kögler M, Vanderhoydonck B, De Jonghe S, Rozenski J, Van Belle K, Herman J, Louat T, Parchina A, Sibley C, Lescrinier E, Herdewijn P. Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 54: 4847-62. PMID 21657202 DOI: 10.1021/Jm2004688 |
0.323 |
|
| 2011 |
Ovaere M, Herdewijn P, Van Meervelt L. The crystal structure of the CeNA:RNA hybrid ce(GCGTAGCG):r(CGCUACGC). Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 7823-30. PMID 21618623 DOI: 10.1002/Chem.201003594 |
0.346 |
|
| 2011 |
Huang Q, Herdewijn P. Synthesis of (E)-3'-phosphonoalkenyl modified nucleoside phosphonates via a highly stereoselective olefin cross-metathesis reaction. The Journal of Organic Chemistry. 76: 3742-53. PMID 21462931 DOI: 10.1021/Jo200033P |
0.373 |
|
| 2011 |
Stella A, Segers K, De Jonghe S, Vanderhoydonck B, Rozenski J, Anné J, Herdewijn P. Synthesis and antibacterial evaluation of a novel series of 2-(1,2-dihydro-3-oxo-3H-pyrazol-2-yl)benzothiazoles. Chemistry & Biodiversity. 8: 253-65. PMID 21337499 DOI: 10.1002/Cbdv.201000241 |
0.322 |
|
| 2011 |
Maiti M, Nauwelaerts K, Lescrinier E, Herdewijn P. Structural and binding study of modified siRNAs with the Argonaute 2 PAZ domain by NMR spectroscopy. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 1519-28. PMID 21268154 DOI: 10.1002/Chem.201000765 |
0.308 |
|
| 2011 |
De Jonghe S, Marchand A, Gao LJ, Calleja A, Cuveliers E, Sienaert I, Herman J, Clydesdale G, Sefrioui H, Lin Y, Pfleiderer W, Waer M, Herdewijn P. Synthesis and in vitro evaluation of 2-amino-4-N-piperazinyl-6-(3,4-dimethoxyphenyl)-pteridines as dual immunosuppressive and anti-inflammatory agents. Bioorganic & Medicinal Chemistry Letters. 21: 145-9. PMID 21131199 DOI: 10.1016/J.Bmcl.2010.11.053 |
0.464 |
|
| 2011 |
Yang S, Froeyen M, Lescrinier E, Marlière P, Herdewijn P. 3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase. Organic & Biomolecular Chemistry. 9: 111-9. PMID 21103490 DOI: 10.1039/C0Ob00554A |
0.353 |
|
| 2011 |
Jang MY, De Jonghe S, Segers K, Anné J, Herdewijn P. Synthesis of novel 5-amino-thiazolo[4,5-d]pyrimidines as E. coli and S. aureus SecA inhibitors. Bioorganic & Medicinal Chemistry. 19: 702-14. PMID 21094610 DOI: 10.1016/J.Bmc.2010.10.027 |
0.352 |
|
| 2011 |
Song XP, Maiti M, Herdewijn P. Enzymatic synthesis of DNA employing pyrophosphate-linked dinucleotide substrates Journal of Systems Chemistry. 2. DOI: 10.1186/1759-2208-2-3 |
0.355 |
|
| 2011 |
Kundarapu M, Marchand D, Dumbre SG, Herdewijn P. Synthesis of new acyclic nucleoside phosphonates (ANPs) substituted on the 1′ and/or 2′ positions Tetrahedron Letters. 52: 2896-6898. DOI: 10.1016/J.Tetlet.2011.10.037 |
0.331 |
|
| 2011 |
Huang Q, Herdewijn P. Synthesis of 3′-S-phosphonomethyl-modified nucleoside phosphonates with a 3′-deoxy-3′-thio-α- L -threosyl sugar moiety European Journal of Organic Chemistry. 3450-3457. DOI: 10.1002/Ejoc.201100177 |
0.378 |
|
| 2011 |
Crauste C, Froeyen M, Anné J, Herdewijn P. Asymmetric synthesis of new β-lactam lipopeptides as bacterial signal peptidase i inhibitors European Journal of Organic Chemistry. 3437-3449. DOI: 10.1002/Ejoc.201100148 |
0.316 |
|
| 2011 |
Chavain N, Herdewijn P. 2′-deoxy-2′-α-C-(hydroxymethyl)adenosine as potential anti-HCV agent European Journal of Organic Chemistry. 1140-1147. DOI: 10.1002/Ejoc.201001448 |
0.32 |
|
| 2011 |
Herdewijn P, Marliere P. Toward Safe Genetically Modified Organisms through the Chemical Diversification of Nucleic Acids Chemical Synthetic Biology. 201-226. DOI: 10.1002/Cbdv.200900083 |
0.332 |
|
| 2010 |
Salim MT, Goto Y, Hamasaki T, Okamoto M, Aoyama H, Hashimoto Y, Musiu S, Paeshuyse J, Neyts J, Froeyen M, Herdewijn P, Baba M. Highly potent and selective inhibition of bovine viral diarrhea virus replication by γ-carboline derivatives. Antiviral Research. 88: 263-8. PMID 20869990 DOI: 10.1016/J.Antiviral.2010.09.013 |
0.338 |
|
| 2010 |
Kaptein SJ, De Burghgraeve T, Froeyen M, Pastorino B, Alen MM, Mondotte JA, Herdewijn P, Jacobs M, de Lamballerie X, Schols D, Gamarnik AV, Sztaricskai F, Neyts J. A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro. Antimicrobial Agents and Chemotherapy. 54: 5269-80. PMID 20837762 DOI: 10.1128/Aac.00686-10 |
0.318 |
|
| 2010 |
D'Alonzo D, Guaragna A, Van Aerschot A, Herdewijn P, Palumbo G. Toward L-homo-DNA: stereoselective de novo synthesis of β-L-erythro-hexopyranosyl nucleosides. The Journal of Organic Chemistry. 75: 6402-10. PMID 20825234 DOI: 10.1021/Jo100691Y |
0.338 |
|
| 2010 |
Robeyns K, Herdewijn P, Van Meervelt L. Comparison between the orthorhombic and tetragonal forms of the heptamer sequence d[GCG(xT)GCG]/d(CGCACGC). Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1028-31. PMID 20823518 DOI: 10.1107/S1744309110031696 |
0.328 |
|
| 2010 |
Giraut A, Herdewijn P. Influence of the linkage between leaving group and nucleoside on substrate efficiency for incorporation in DNA catalyzed by reverse transcriptase. Chembiochem : a European Journal of Chemical Biology. 11: 1399-403. PMID 20533494 DOI: 10.1002/Cbic.201000128 |
0.357 |
|
| 2010 |
Giraut A, Song XP, Froeyen M, Marlière P, Herdewijn P. Iminodiacetic-phosphoramidates as metabolic prototypes for diversifying nucleic acid polymerization in vivo. Nucleic Acids Research. 38: 2541-50. PMID 20097909 DOI: 10.1093/Nar/Gkp1246 |
0.36 |
|
| 2010 |
Herdewijn P. Nucleic acids with a six-membered 'carbohydrate' mimic in the backbone. Chemistry & Biodiversity. 7: 1-59. PMID 20087996 DOI: 10.1002/Cbdv.200900185 |
0.322 |
|
| 2010 |
Jang MY, De Jonghe S, Van Belle K, Louat T, Waer M, Herdewijn P. Synthesis, immunosuppressive activity and structure-activity relationship study of a new series of 4-N-piperazinyl-thieno[2,3-d]pyrimidine analogues. Bioorganic & Medicinal Chemistry Letters. 20: 844-7. PMID 20064721 DOI: 10.1016/J.Bmcl.2009.12.098 |
0.368 |
|
| 2010 |
Ramaswamy A, Froeyen M, Herdewijn P, Ceulemans A. Helical structure of xylose-DNA. Journal of the American Chemical Society. 132: 587-95. PMID 20017539 DOI: 10.1021/Ja9065877 |
0.32 |
|
| 2010 |
Cesnek M, Herdewijn P. Synthesis And Anti-Hiv Activity Of New 3'-O-Phosphonomethyl Nucleosides Heterocycles. 82: 663-687. DOI: 10.3987/Com-10-S(E)42 |
0.345 |
|
| 2010 |
Cesnek M, Herdewijn P. Synthesis and Antiviral Activity of 3-O-Phosphonomethyl Nucleosides Antiviral Research. 86. DOI: 10.1016/J.Antiviral.2010.02.423 |
0.318 |
|
| 2010 |
Aerschot AV, Saison-Behmoaras T, Rozenski J, Hendrix C, Schepers G, Verhoeven G, Herdewijn P. Conjugation of Oligonucleotides to 3′‐Polar Moieties Bulletin Des SociéTéS Chimiques Belges. 104: 717-720. DOI: 10.1002/Bscb.19951041208 |
0.313 |
|
| 2010 |
Herdewijn P, Aerschot Av, Wigerinck P, Kerremans L. Synthesis of 8‐Mercapto‐2′,3′‐Dideoxyadenosine and 8‐Mercapto‐2′,3′‐Dideoxyinosine Bulletin Des SociéTéS Chimiques Belges. 100: 183-184. DOI: 10.1002/Bscb.19911000212 |
0.336 |
|
| 2010 |
Herdewijn P, Aerschot Av. Synthesis of trideoxyhexopyranosylated and hexenopyranosylated nucleoside analogues as potential anti‐HIV agents Bulletin Des SociéTéS Chimiques Belges. 99: 895-901. DOI: 10.1002/Bscb.19900991106 |
0.331 |
|
| 2010 |
Aerschot AV, Janssen G, Herdewijn P. Nucleoside Analogues with a 1,4‐Dioxane, 1,4‐Oxathiane or 1,4‐Oxazine Ring Structure as the Carbohydrate Fragment Bulletin Des SociéTéS Chimiques Belges. 99: 769-777. DOI: 10.1002/Bscb.19900991002 |
0.318 |
|
| 2010 |
Herdewijn P, Aerschot Av. Synthesis of 2',3'-disubstituted 3'-deoxythymidine derivatives Bulletin Des SociéTéS Chimiques Belges. 98: 943-947. DOI: 10.1002/Bscb.19890981207 |
0.384 |
|
| 2010 |
Aerschot Av, Herdewijn P. 2,3′‐Difluoro‐and 3′‐Azido‐2′‐Fluoro Substituted Dideoxypyrimidines as Potential Anti‐HIV Agents Bulletin Des SociéTéS Chimiques Belges. 98: 937-941. DOI: 10.1002/Bscb.19890981206 |
0.348 |
|
| 2010 |
Aerschot Av, Herdewijn P. Synthesis of 2'-chloro-2',3'-dideoxy-2',3'-didehydro nucleosides Bulletin Des SociéTéS Chimiques Belges. 98: 931-936. DOI: 10.1002/Bscb.19890981205 |
0.36 |
|
| 2009 |
Huang Q, Herdewijn P. Synthesis of 3'-o-phosphonoethyl nucleosides with an adenine and a thymine base moiety. Nucleosides, Nucleotides & Nucleic Acids. 28: 337-51. PMID 20183588 DOI: 10.1080/15257770903044184 |
0.366 |
|
| 2009 |
Abramov M, Renders M, Herdewijn P. Synthesis of 2'-N-formamido nucleosides and biological evaluation. Nucleosides, Nucleotides & Nucleic Acids. 28: 1042-50. PMID 20183572 DOI: 10.1080/15257770903362164 |
0.306 |
|
| 2009 |
Mikhailov SN, Timofeev EN, Drenichev MS, Efimtseva EV, Herdewijn P, Roesch EB, Lemaitre MM. Oligodeoxynucleotides containing N1-methyl-2'-deoxyadenosine and N6-methyl-2'-deoxyadenosine. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 4.36 1-19. PMID 19746356 DOI: 10.1002/0471142700.Nc0436S38 |
0.314 |
|
| 2009 |
D'Alonzo D, Van Aerschot A, Guaragna A, Palumbo G, Schepers G, Capone S, Rozenski J, Herdewijn P. Synthesis and base pairing properties of 1',5'-anhydro-L-hexitol nucleic acids (L-HNA). Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 10121-31. PMID 19739223 DOI: 10.1002/Chem.200901847 |
0.308 |
|
| 2009 |
Zlatev I, Giraut A, Morvan F, Herdewijn P, Vasseur J. Delta-di-carboxybutyl phosphoramidate of 2'-deoxycytidine-5'-monophosphate as substrate for DNA polymerization by HIV-1 reverse transcriptase. Bioorganic & Medicinal Chemistry. 17: 7008-7014. PMID 19716707 DOI: 10.1016/J.Bmc.2009.08.001 |
0.324 |
|
| 2009 |
Michielssens S, Tien Trung N, Froeyen M, Herdewijn P, Tho Nguyen M, Ceulemans A. Hydrolysis of aspartic acid phosphoramidate nucleotides: a comparative quantum chemical study. Physical Chemistry Chemical Physics : Pccp. 11: 7274-85. PMID 19672539 DOI: 10.1039/B906020K |
0.331 |
|
| 2009 |
Giraut A, Dyubankova N, Song XP, Herdewijn P. Phosphodiester substrates for incorporation of nucleotides in DNA using HIV-1 reverse transcriptase Chembiochem. 10: 2246-2252. PMID 19637144 DOI: 10.1002/Cbic.200900270 |
0.391 |
|
| 2009 |
Paeshuyse J, Letellier C, Froeyen M, Dutartre H, Vrancken R, Canard B, Clercq ED, Gueiffier A, Teulade J, Herdewijn P, Puerstinger G, Koenen F, Kerkhofs P, Baraldi PG, Neyts J. A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase. Antiviral Research. 82: 141-147. PMID 19428605 DOI: 10.1016/J.Antiviral.2009.02.192 |
0.33 |
|
| 2009 |
Renders M, Abramov M, Froeyen M, Herdewijn P. Polymerase-catalysed incorporation of glucose nucleotides into a DNA duplex. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 5463-70. PMID 19308979 DOI: 10.1002/Chem.200801951 |
0.325 |
|
| 2009 |
Bramsen JB, Laursen MB, Nielsen AF, Hansen TB, Bus C, Langkjoør N, Babu BR, Højland T, Abramov M, Van Aerschot A, Odadzic D, Smicius R, Haas J, Andree C, Barman J, ... ... Herdewijn P, et al. A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity Nucleic Acids Research. 37: 2867-2881. PMID 19282453 DOI: 10.1093/Nar/Gkp106 |
0.305 |
|
| 2009 |
Vijver PVd, Vondenhoff GHM, Denivelle S, Rozenski J, Verhaegen J, Aerschot AV, Herdewijn P. Antibacterial 5′-O-(N-dipeptidyl)-sulfamoyladenosines Bioorganic & Medicinal Chemistry. 17: 260-269. PMID 19070499 DOI: 10.1016/J.Bmc.2008.11.054 |
0.342 |
|
| 2009 |
Lescrinier T, Busson R, Winter HD, Hendrix C, Janssen G, Pannecouque C, Rozenski J, Aerschot AV, Herdewijn P. alpha-Amino acids derived from ornithine as building blocks for peptide synthesis. Journal of Peptide Research. 49: 183-189. PMID 9147314 DOI: 10.1111/J.1399-3011.1997.Tb00613.X |
0.354 |
|
| 2009 |
Wigerinck P, Aerschot AV, Claes P, Balzarini J, Clercq ED, Herdewijn P. 3′‐(1,2,3‐Triazol‐1‐yl)‐2′,3′‐dideoxythymidine and 3′‐(1,2,3‐triazol‐1‐yl)‐2′,3′‐dideoxyuridine Journal of Heterocyclic Chemistry. 26: 1635-1642. DOI: 10.1002/Jhet.5570260624 |
0.34 |
|
| 2008 |
Renders M, Lievrouw R, Krecmerová M, Holý A, Herdewijn P. Enzymatic polymerization of phosphonate nucleosides. Chembiochem : a European Journal of Chemical Biology. 9: 2883-8. PMID 19006151 DOI: 10.1002/Cbic.200800494 |
0.343 |
|
| 2008 |
Liu FW, Di Salvo A, Herdewijn P. Synthesis of 2′-cyclohexenylnucleosides and corresponding CeNA building blocks Current Protocols in Nucleic Acid Chemistry. PMID 18551425 DOI: 10.1002/0471142700.Nc0120S33 |
0.404 |
|
| 2008 |
Vijver PVd, Ostrowski T, Sproat B, Goebels J, Rutgeerts O, Aerschot AV, Waer M, Herdewijn P. Aminoacyl-tRNA synthetase inhibitors as potent and synergistic immunosuppressants. Journal of Medicinal Chemistry. 51: 3020-3029. PMID 18438987 DOI: 10.1021/Jm8000746 |
0.352 |
|
| 2008 |
Abramov M, Schepers G, Van Aerschot A, Van Hummelen P, Herdewijn P. HNA and ANA high-affinity arrays for detections of DNA and RNA single-base mismatches. Biosensors & Bioelectronics. 23: 1728-32. PMID 18378134 DOI: 10.1016/J.Bios.2008.01.033 |
0.326 |
|
| 2008 |
Terrazas M, Marlière P, Herdewijn P. Enzymatically catalyzed DNA synthesis using L-Asp-dGMP, L-Asp-dCMP, and L-Asp-dTMP Chemistry and Biodiversity. 5: 31-39. PMID 18205125 DOI: 10.1002/Cbdv.200890013 |
0.329 |
|
| 2008 |
Robeyns K, Herdewijn P, Van Meervelt L. Influence of the incorporation of a cyclohexenyl nucleic acid (CeNA) residue onto the sequence d(CGCGAATTCGCG) Nucleic Acids Research. 36: 1407-1414. PMID 18160414 DOI: 10.1093/Nar/Gkm1132 |
0.345 |
|
| 2008 |
Vrancken R, Paeshuyse J, Haegeman A, Puerstinger G, Froeyen M, Herdewijn P, Kerkhofs P, Neyts J, Koenen F. Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase. Antiviral Research. 77: 114-119. PMID 17997169 DOI: 10.1016/J.Antiviral.2007.09.006 |
0.317 |
|
| 2008 |
D’Alonzo D, Guaragna A, Aerschot AV, Herdewijn P, Palumbo G. De novo approach to L-anhydrohexitol nucleosides as building blocks for the synthesis of L-hexitol nucleic acids (L-HNA) Tetrahedron Letters. 49: 6068-6070. DOI: 10.1016/J.Tetlet.2008.07.159 |
0.319 |
|
| 2008 |
Yang S, Busson R, Herdewijn P. Synthesis of N-methyl-d-ribopyranuronamide nucleosides Tetrahedron. 64: 10062-10067. DOI: 10.1016/J.Tet.2008.08.027 |
0.367 |
|
| 2008 |
Bobkov GV, Mikhailov SN, Aerschot AV, Herdewijn P. Phosphoramidite building blocks for efficient incorporation of 2′-O-aminoethoxy(and propoxy)methyl nucleosides into oligonucleotides Tetrahedron. 64: 6238-6251. DOI: 10.1016/J.Tet.2008.04.110 |
0.363 |
|
| 2008 |
Mikhailov SN, Kulikova IV, Nauwelaerts K, Herdewijn P. Synthesis of 2′-O-α-d-ribofuranosyladenosine, monomeric unit of poly(ADP-ribose) Tetrahedron. 64: 2871-2876. DOI: 10.1016/J.Tet.2008.01.028 |
0.332 |
|
| 2007 |
Abramov M, Herdewijn P. Synthesis of altritol nucleoside phosphoramidites for oligonucleotide synthesis. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 1.18. PMID 18428966 DOI: 10.1002/0471142700.Nc0118S30 |
0.386 |
|
| 2007 |
Vorbrüggen H, Lagoja IM, Herdewijn P. Synthesis of ribonucleosides by condensation using trimethylsilyl triflate Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. PMID 18428961 DOI: 10.1002/0471142700.Nc0113S27 |
0.324 |
|
| 2007 |
Mikhailov SN, Bobkov GV, Brilliantov KV, Rozenski J, Van Aerschot A, Herdewijn P, Fisher MH, Juliano RL. 2'-O-hydroxyalkoxymethylribonucleosides and their incorporation into oligoribonucleotides. Nucleosides, Nucleotides & Nucleic Acids. 26: 1509-12. PMID 18066816 DOI: 10.1080/15257770701543007 |
0.314 |
|
| 2007 |
Paeshuyse J, Chezal J, Froeyen M, Leyssen P, Dutartre H, Vrancken R, Canard B, Letellier C, Li T, Mittendorfer H, Koenen F, Kerkhofs P, Clercq ED, Herdewijn P, Puerstinger G, et al. The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication. Journal of Virology. 81: 11046-11053. PMID 17686854 DOI: 10.1128/Jvi.00388-07 |
0.318 |
|
| 2007 |
Adelfinskaya O, Terrazas M, Froeyen M, Marlière P, Nauwelaerts K, Herdewijn P. Polymerase-catalyzed synthesis of DNA from phosphoramidate conjugates of deoxynucleotides and amino acids Nucleic Acids Research. 35: 5060-5072. PMID 17652326 DOI: 10.1093/Nar/Gkm498 |
0.33 |
|
| 2007 |
Nauwelaerts K, Fisher M, Froeyen M, Lescrinier E, Aerschot AV, Xu D, DeLong R, Kang H, Juliano RL, Herdewijn P. Structural characterization and biological evaluation of small interfering RNAs containing cyclohexenyl nucleosides. Journal of the American Chemical Society. 129: 9340-8. PMID 17616127 DOI: 10.1021/Ja067047Q |
0.322 |
|
| 2007 |
Lagoja IM, Herdewijn P. Preparation of guanine and diaminopurine from biuret: Part III Chemistry and Biodiversity. 4: 818-822. PMID 17443891 DOI: 10.1002/Cbdv.200790066 |
0.304 |
|
| 2007 |
Froeyen M, Morvan F, Vasseur J, Nielsen P, Aerschot AV, Rosemeyer H, Herdewijn P. Conformational and chiral selection of oligonucleotides. Chemistry & Biodiversity. 4: 803-817. PMID 17443890 DOI: 10.1002/Cbdv.200790065 |
0.32 |
|
| 2007 |
Zhou D, Froeyen M, Rozenski J, Van Aerschot A, Herdewijn P. Chemical etiology of nucleic acids: aminopropyl nucleic acids (APNAs). Chemistry & Biodiversity. 4: 740-61. PMID 17443886 DOI: 10.1002/Cbdv.200790061 |
0.336 |
|
| 2007 |
Adelfinskaya O, Herdewijn P. Amino acid phosphoramidate nucleotides as alternative substrates for HIV-1 reverse transcriptase Angewandte Chemie - International Edition. 46: 4356-4358. PMID 17443759 DOI: 10.1002/Anie.200605016 |
0.385 |
|
| 2007 |
Renders M, Emmerechts G, Rozenski J, Krecmerová M, Holý A, Herdewijn P. Enzymatic synthesis of phosphonomethyl oligonucleotides by therminator polymerase. Angewandte Chemie (International Ed. in English). 46: 2501-4. PMID 17310479 DOI: 10.1002/Anie.200603435 |
0.376 |
|
| 2007 |
Fisher M, Abramov M, Van Aerschot A, Xu D, Juliano RL, Herdewijn P. Inhibition of MDR1 expression with altritol-modified siRNAs. Nucleic Acids Research. 35: 1064-74. PMID 17264131 DOI: 10.1093/Nar/Gkl1126 |
0.324 |
|
| 2007 |
Herdewijn P, Juliano R. Nucleic acids with a six-membered carbohydrate mimic and RNA interference Blood Cells, Molecules, and Diseases. 38: 100-101. PMID 17208470 DOI: 10.1016/J.Bcmd.2006.10.005 |
0.303 |
|
| 2007 |
Nauwelaerts K, Lescrinier E, Herdewijn P. Structure of the α-homo-DNA:RNA duplex and the function of twist and slide to catalogue nucleic acid duplexes Chemistry - a European Journal. 13: 90-98. PMID 16991180 DOI: 10.1002/Chem.200600363 |
0.34 |
|
| 2007 |
Horváth A, Ruttens B, Herdewijn P. Stereoselective synthesis of (-)-ara-cyclohexenyl-adenine Tetrahedron Letters. 48: 3621-3623. DOI: 10.1016/J.Tetlet.2007.03.031 |
0.364 |
|
| 2007 |
Lambertucci C, Schepers G, Cristalli G, Herdewijn P, Aerschot AV. Synthesis and evaluation of hexitol nucleoside congeners as ambiguous nucleosides Tetrahedron Letters. 48: 2143-2145. DOI: 10.1016/J.Tetlet.2007.01.111 |
0.354 |
|
| 2007 |
Viña D, Wu T, Renders M, Laflamme G, Herdewijn P. Synthesis of 3′-O-phosphonomethyl nucleosides with an adenine base moiety Tetrahedron. 63: 2634-2646. DOI: 10.1016/J.Tet.2007.01.032 |
0.397 |
|
| 2007 |
Paeshuyse J, Chezal J, Froeyen M, Leyssen P, Dutartre H, Vrancken R, Canard B, Letellier C, Li T, Mittendorfer H, Koenen F, Kerkhofs P, Clercq ED, Herdewijn P, Puerstinger G, et al. The Imidazopyrrolopyridine Analogue AG110 is a Novel, Highly Selective Inhibitor of Pestivirus Replication and Targets the viral RNA-dependent RNA Polymerase Antiviral Research. 74. DOI: 10.1016/J.Antiviral.2007.01.038 |
0.305 |
|
| 2007 |
Goulioukina N, Wehbe J, Marchand D, Busson R, Lescrinier E, Heindl D, Herdewijn P. Synthesis of nicotinamide adenine dinucleotide (NAD) analogues with a sugar modified nicotinamide moiety Helvetica Chimica Acta. 90: 1266-1278. DOI: 10.1002/Hlca.200790127 |
0.381 |
|
| 2007 |
Timofeev EN, Mikhailov SN, Zuev AN, Efimtseva EV, Herdewijn P, Somers RL, Lemaitre MM. Oligodeoxynucleotides containing 2'-deoxy-1-methyladenosine and Dimroth rearrangement Helvetica Chimica Acta. 90: 928-937. DOI: 10.1002/Hlca.200790093 |
0.345 |
|
| 2007 |
Abramov M, Schepers G, Van Aerschot A, Herdewijn P. Fmoc-protected altritol phosphoramidite building blocks and their application in the synthesis of altritol nucleic acids (ANAs) European Journal of Organic Chemistry. 1446-1456. DOI: 10.1002/Ejoc.200600868 |
0.385 |
|
| 2006 |
Mikhailov SN, Efimtseva EV, Rodionov AA, Bobkov GV, Kulikova IV, Herdewijn P. Synthesis of 2′‐O‐β‐d‐Ribofuranosylnucleosides Current Protocols in Human Genetics. 27. PMID 18428962 DOI: 10.1002/0471142700.Nc0114S27 |
0.311 |
|
| 2006 |
Puerstinger G, Paeshuyse J, Herdewijn P, Rozenski J, Clercq ED, Neyts J. Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines: a new class of pestivirus inhibitors. Bioorganic & Medicinal Chemistry Letters. 16: 5345-5349. PMID 16901692 DOI: 10.1002/CHIN.200705208 |
0.34 |
|
| 2006 |
Wu T, Nauwelaerts K, Aerschot AV, Froeyen M, Lescrinier E, Herdewijn P. Base-base interactions in the minor groove of double-stranded DNA. Journal of Organic Chemistry. 71: 5423-5431. PMID 16839119 DOI: 10.1021/Jo052194C |
0.323 |
|
| 2006 |
Herdewijn P. The interplay between antiviral activity, oligonucleotide hybridisation and nucleic acids incorporation studies Antiviral Research. 71: 317-321. PMID 16690140 DOI: 10.1016/J.Antiviral.2006.04.004 |
0.337 |
|
| 2006 |
Fraipont C, Sapunaric F, Zervosen A, Auger G, Devreese B, Lioux T, Blanot D, Mengin-Lecreulx D, Herdewijn P, Beeumen JV, Frère J, Nguyen-Distèche M. Glycosyl Transferase Activity of the Escherichia coli Penicillin-Binding Protein 1b: Specificity Profile for the Substrate† Biochemistry. 45: 4007-4013. PMID 16548528 DOI: 10.1021/Bi051055M |
0.312 |
|
| 2006 |
Paeshuyse J, Leyssen P, Mabery E, Boddeker N, Vrancken R, Froeyen M, Ansari IH, Dutartre H, Rozenski J, Gil LH, Letellier C, Lanford R, Canard B, Koenen F, Kerkhofs P, ... ... Herdewijn P, et al. A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase. Journal of Virology. 80: 149-60. PMID 16352539 DOI: 10.1128/Jvi.80.1.149-160.2006 |
0.344 |
|
| 2006 |
Bobkov GV, Brilliantov KV, Mikhailov SN, Rozenski J, Aerschot AV, Herdewijn P. Synthesis of Oligoribonucleotides Containing Pyrimidine 2'- O -[(Hydroxyalkoxy)methyl]ribonucleosides Collection of Czechoslovak Chemical Communications. 71: 804-819. DOI: 10.1135/Cccc20060804 |
0.306 |
|
| 2006 |
Zhou D, Lagoja IM, Van Aerschot A, Herdewijn P. Synthesis of Aminopropyl Phosphonate Nucleosides with Purine and Pyrimidine Bases Collection of Czechoslovak Chemical Communications. 71: 15-34. DOI: 10.1135/Cccc20060015 |
0.394 |
|
| 2006 |
Jang MY, Jonghe SD, Gao LJ, Herdewijn P. Regioselective cross-coupling reactions and nucleophilic aromatic substitutions on a 5,7-dichloropyrido[4,3-d]pyrimidine scaffold Tetrahedron Letters. 47: 8917-8920. DOI: 10.1016/J.Tetlet.2006.10.056 |
0.344 |
|
| 2006 |
Borgions F, Ghyssels D, Aerschot AV, Rozenski J, Herdewijn P. Synthetic dsDNA-binding peptides using natural compounds as model Helvetica Chimica Acta. 89: 1194-1219. DOI: 10.1002/Hlca.200690118 |
0.308 |
|
| 2006 |
Sun DQ, Busson R, Herdewijn P. Synthesis of deoxygenated disaccharide precursors for modified lipid II synthesis European Journal of Organic Chemistry. 5158-5166. DOI: 10.1002/Ejoc.200600515 |
0.336 |
|
| 2006 |
Jang M, Jonghe SD, Gao L, Rozenski J, Herdewijn P. Development of synthetic strategies for the construction of pyrido[4,3-d]-pyrimidine libraries - the discovery of a new class of PDE-4 inhibitors European Journal of Organic Chemistry. 2006: 4257-4269. DOI: 10.1002/Ejoc.200600339 |
0.348 |
|
| 2005 |
Mikhailov SN, Efimtseva EV, Rodionov AA, Shelkunova AA, Rozenski J, Emmerechts G, Schepers G, Aerschot AV, Herdewijn P. Synthesis of RNA containing O-beta-D-ribofuranosyl-(1''-2')-adenosine-5''-phosphate and 1-methyladenosine, minor components of tRNA. Chemistry & Biodiversity. 2: 1153-1163. PMID 17193197 DOI: 10.1002/Cbdv.200590085 |
0.346 |
|
| 2005 |
Zhou D, Lagoja IM, Rozenski J, Busson R, Van Aerschot A, Herdewijn P. Synthesis and properties of aminopropyl nucleic acids. Chembiochem : a European Journal of Chemical Biology. 6: 2298-304. PMID 16276500 DOI: 10.1002/Cbic.200500170 |
0.367 |
|
| 2005 |
Gu P, Schepers G, Griebel C, Rozenski J, Gais H, Herdewijn P, Aerschot AV. ENZYMATIC RESOLUTION AND BASE PAIRING PROPERTIES OF D- AND L-CYCLOHEXENYL NUCLEIC ACIDS (CeNA) Nucleosides, Nucleotides & Nucleic Acids. 24: 993-998. PMID 16248079 DOI: 10.1081/Ncn-200060326 |
0.357 |
|
| 2005 |
Kempeneers V, Renders M, Froeyen M, Herdewijn P. Investigation of the DNA-dependent cyclohexenyl nucleic acid polymerization and the cyclohexenyl nucleic acid-dependent DNA polymerization Nucleic Acids Research. 33: 3828-3836. PMID 16027107 DOI: 10.1093/Nar/Gki695 |
0.319 |
|
| 2005 |
Vijgen S, Nauwelaerts K, Wang J, Aerschot AV, Lagoja I, Herdewijn P. Synthesis and Conformational Analysis of a Ribo-Type Cyclohexenyl Nucleoside Journal of Organic Chemistry. 70: 4591-4597. PMID 15932294 DOI: 10.1021/Jo048037F |
0.312 |
|
| 2005 |
Nauwelaerts K, Lescrinier E, Sclep G, Herdewijn P. Cyclohexenyl nucleic acids: Conformationally flexible oligonucleotides Nucleic Acids Research. 33: 2452-2463. PMID 15863723 DOI: 10.1093/Nar/Gki538 |
0.357 |
|
| 2005 |
Wu T, Froeyen M, Kempeneers V, Pannecouque C, Wang J, Busson R, Clercq ED, Herdewijn P. Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents. Journal of the American Chemical Society. 127: 5056-5065. PMID 15810840 DOI: 10.1021/Ja043045Z |
0.304 |
|
| 2005 |
Maier T, Przylas I, Strater N, Herdewijn P, Saenger W. Reinforced HNA backbone hydration in the crystal structure of a decameric HNA/RNA hybrid. Journal of the American Chemical Society. 127: 2937-43. PMID 15740130 DOI: 10.1021/Ja045843V |
0.332 |
|
| 2005 |
Kolb G, Reigadas S, Boiziau C, Van Aerschot A, Arzumanov A, Gait MJ, Herdewijn P, Toulmé JJ. Hexitol nucleic acid-containing aptamers are efficient ligands of HIV-1 TAR RNA Biochemistry. 44: 2926-2933. PMID 15723535 DOI: 10.1021/Bi048393S |
0.311 |
|
| 2005 |
Vanheusden V, Munier-Lehmann H, Froeyen M, Busson R, Rozenski J, Herdewijn P, Van Calenbergh S. Discovery of bicyclic thymidine analogues as selective and high-affinity inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase. Journal of Medicinal Chemistry. 47: 6187-94. PMID 15566289 DOI: 10.1021/Jm040847W |
0.31 |
|
| 2005 |
Vanheusden V, Busson R, Herdewijn P, Van Calenbergh S. Synthesis and conformational analysis of 1-[2,4-dideoxy-4-C-hydroxymethyl-alpha-l-lyxopyranosyl]thymine. The Journal of Organic Chemistry. 69: 4446-53. PMID 15202900 DOI: 10.1021/Jo040130G |
0.338 |
|
| 2005 |
Herdewijn P. The Diels-Alder cyclo addition as key reaction for the synthesis of cyclohexenyl nucleosides Collection of Czechoslovak Chemical Communications. 7: 29-37. DOI: 10.1135/Css200507029 |
0.309 |
|
| 2005 |
Lioux T, Busson R, Rozenski J, Nguyen-Distèche M, Frère J, Herdewijn P. Synthesis of Peptidoglycan Units with UDP at the Anomeric Position Collection of Czechoslovak Chemical Communications. 70: 1615-1641. DOI: 10.1135/Cccc20051615 |
0.344 |
|
| 2005 |
Bardiot D, Rosemeyer H, Lescrinier E, Rozenski J, Aerschot AV, Herdewijn P. Synthesis and Properties of Oligonucleotides Containing 2,4-Dihydroxycyclohexyl Nucleosides Helvetica Chimica Acta. 88: 3210-3224. DOI: 10.1002/Hlca.200590258 |
0.386 |
|
| 2004 |
Kempeneers V, Froeyen M, Vastmans K, Herdewijn P. Influence of threose nucleoside units on the catalytic activity of a hammerhead ribozyme Chemistry and Biodiversity. 1: 112-123. PMID 17191779 DOI: 10.1002/Cbdv.200490002 |
0.35 |
|
| 2004 |
Lagoja IM, Herdewijn P. One-step synthesis of hypoxanthine from glycinamide and diformylurea Chemistry and Biodiversity. 1: 106-111. PMID 17191778 DOI: 10.1002/Cbdv.200490001 |
0.326 |
|
| 2004 |
Morreel K, Ralph J, Lu F, Goeminne G, Busson R, Herdewijn P, Goeman JL, Van der Eycken J, Boerjan W, Messens E. Phenolic profiling of caffeic acid O-methyltransferase-deficient poplar reveals novel benzodioxane oligolignols. Plant Physiology. 136: 4023-36. PMID 15563622 DOI: 10.1104/Pp.104.049312 |
0.314 |
|
| 2004 |
Kang H, Fisher MH, Xu D, Miyamoto YJ, Marchand A, Van Aerschot A, Herdewijn P, Juliano RL. Inhibition of MDR1 gene expression by chimeric HNA antisense oligonucleotides. Nucleic Acids Research. 32: 4411-9. PMID 15316104 DOI: 10.1093/Nar/Gkh775 |
0.312 |
|
| 2004 |
Astriab-Fisher A, Fisher MH, Juliano R, Herdewijn P. Increased uptake of antisense oligonucleotides by delivery as double stranded complexes. Biochemical Pharmacology. 68: 403-7. PMID 15242806 DOI: 10.1016/J.Bcp.2004.03.040 |
0.327 |
|
| 2004 |
Abramov M, Marchand A, Calleja-Marchand A, Herdewijn P. Synthesis of D-altritol nucleosides with a 3'-O-tert-butyldimethylsilyl protecting group. Nucleosides, Nucleotides & Nucleic Acids. 23: 439-55. PMID 15043165 DOI: 10.1081/NCN-120028338 |
0.323 |
|
| 2004 |
Golubeva AS, Ermolinsky BS, Efimtseva EV, Tunitskaya VL, Van Aerschot A, Herdewijn P, Mikhailov SN, Kochetkov SN. Interaction of HIV-1 reverse transcriptase with modified oligonucleotide primers containing 2′-O-β-D-ribofuranosyladenosine Biochemistry (Moscow). 69: 130-136. PMID 15000678 DOI: 10.1023/B:Biry.0000018942.76948.B0 |
0.364 |
|
| 2004 |
Wu T, Froeyen M, Schepers G, Mullens K, Rozenski J, Busson R, Aerschot aAV, Herdewijn P. Synthesis and Stability of Oligonucleotides Containing Acyclic Achiral Nucleoside Analogues with Two Base Moieties Organic Letters. 6: 51-54. PMID 14703348 DOI: 10.1021/Ol0360647 |
0.348 |
|
| 2004 |
Lagoja IM, Nauwelaerts K, Bal-Mahieu C, Pasqualini M, Bailly C, Herdewijn P. Synthesis and leukemia cell growth inhibition of a series of 1,3-dithiazolylbenzene derivatives Collection of Czechoslovak Chemical Communications. 69: 1491-1498. DOI: 10.1135/Cccc20041491 |
0.392 |
|
| 2004 |
Gu P, Griebel C, Aerschot AV, Rozenski J, Busson R, Gais H, Herdewijn P. Synthesis of enantiomeric-pure cyclohexenyl nucleoside building blocks for oligonucleotide synthesis Tetrahedron. 60: 2111-2123. DOI: 10.1016/J.Tet.2003.12.052 |
0.306 |
|
| 2003 |
Gu P, Schepers G, Rozenski J, Aerschot AV, Herdewijn P. Base pairing properties of D- and L-cyclohexene nucleic acids (CeNA). Oligonucleotides. 13: 479-489. PMID 15025914 DOI: 10.1089/154545703322860799 |
0.342 |
|
| 2003 |
Pochet S, Kaminski PA, Aerschot AV, Herdewijn P, Marlière P. Replication of hexitol oligonucleotides as a prelude to the propagation of a third type of nucleic acid in vivo Comptes Rendus Biologies. 326: 1175-1184. PMID 14746272 DOI: 10.1016/J.Crvi.2003.10.004 |
0.373 |
|
| 2003 |
Kempeneers V, Vastmans K, Rozenski J, Herdewijn P. Recognition of threosyl nucleotides by DNA and RNA polymerases Nucleic Acids Research. 31: 6221-6226. PMID 14576309 DOI: 10.1093/Nar/Gkg833 |
0.34 |
|
| 2003 |
Van Aerschot A, Marchand A, Schepers G, Van den Eynde W, Rozenski J, Busson R, Herdewijn P. Methylated hexitol nucleic acids, towards congeners with improved antisense potential. Nucleosides, Nucleotides & Nucleic Acids. 22: 1227-9. PMID 14565386 DOI: 10.1081/Ncn-120022842 |
0.373 |
|
| 2003 |
Efimtseva EV, Mikhailov SN, Rozenski J, Busson R, Aerschot AV, Herdewijn P. Chemical Incorporation of 1-Methyladenosine, Minor tRNA Component, into Oligonucleotides Nucleosides, Nucleotides & Nucleic Acids. 22: 1113-1115. PMID 14565357 DOI: 10.1081/Ncn-120022749 |
0.342 |
|
| 2003 |
Efimtseva EV, Shelkunova AA, Mikhailov SN, Nauwelaerts K, Rozenski J, Lescrinier E, Herdewijn P. Synthesis and Conformational Properties of O-β-D-Ribofuranosyl-(1″-2′)-guanosine and (Adenosine)-5″-phosphate Nucleosides, Nucleotides & Nucleic Acids. 22: 1109-1111. PMID 14565356 DOI: 10.1002/CHIN.200406196 |
0.365 |
|
| 2003 |
Aerschot AV, Schepers G, Busson R, Neyts J, Clercq ED, Herdewijn P. Synthesis and antiviral evaluation of ribavirin congeners containing a hexitol moiety. Nucleosides, Nucleotides & Nucleic Acids. 22: 849-851. PMID 14565294 DOI: 10.1081/Ncn-120022669 |
0.383 |
|
| 2003 |
Gu P, Morral J, Wang J, Rozenski J, Busson R, Aerschot AV, Clercq ED, Herdewijn P. Synthesis and biological evaluation of a series of new cyclohexenyl nucleosides. Nucleosides, Nucleotides & Nucleic Acids. 22: 845-847. PMID 14565293 DOI: 10.1081/Ncn-120022668 |
0.365 |
|
| 2003 |
Vanheusden V, Munier-Lehmann H, Froeyen M, Dugué L, Heyerick A, De Keukeleire D, Pochet S, Busson R, Herdewijn P, Van Calenbergh S. 3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase. Journal of Medicinal Chemistry. 46: 3811-21. PMID 12930144 DOI: 10.1021/Jm021108N |
0.357 |
|
| 2003 |
Efimtseva EV, Shelkunova AA, Mikhailov SN, Nauwelaerts K, Rozenski J, Lescrinier E, Herdewijn P. Synthesis and properties of phosphorylated 3'-O-beta-D-ribofuranosyl-2'-deoxythymidine. Nucleosides, Nucleotides & Nucleic Acids. 22: 359-371. PMID 12885119 DOI: 10.1081/Ncn-120022028 |
0.36 |
|
| 2003 |
Lescrinier E, Froeyen M, Herdewijn P. Difference in conformational diversity between nucleic acids with a six-membered 'sugar' unit and natural 'furanose' nucleic acids Nucleic Acids Research. 31: 2975-2989. PMID 12799423 DOI: 10.1093/Nar/Gkg407 |
0.355 |
|
| 2003 |
Gu P, Morral J, Wang J, Rozenski J, Busson R, Aerschot AV, Clercq ED, Herdewijn P. Synthesis and antiviral activity of a series of new cyclohexenyl nucleosides. Antiviral Chemistry & Chemotherapy. 14: 31-37. PMID 12790514 DOI: 10.1177/095632020301400103 |
0.349 |
|
| 2003 |
Aerschot AV, Schepers G, Busson R, Rozenski J, Neyts J, Clercq ED, Herdewijn P. Ribavirin derivatives with a hexitol moiety: synthesis and antiviral evaluation. Antiviral Chemistry & Chemotherapy. 14: 23-30. PMID 12790513 DOI: 10.1177/095632020301400102 |
0.303 |
|
| 2003 |
Wang J, Viña D, Busson R, Herdewijn P. Stereocontrolled synthesis of ara-type cyclohexenyl nucleosides Journal of Organic Chemistry. 68: 4499-4505. PMID 12762756 DOI: 10.1021/Jo0300946 |
0.309 |
|
| 2003 |
Lagoja IM, Pochet S, Boudou V, Little R, Lescrinier E, Rozenski J, Herdewijn P. A short path synthesis of [13C/15N] multilabeled pyrimidine nucleosides starting from glucopyranose nucleosides. Journal of Organic Chemistry. 68: 1867-1871. PMID 12608803 DOI: 10.1021/Jo0205098 |
0.306 |
|
| 2003 |
Chaltin P, Borgions F, Aerschot AV, Herdewijn P. Comparison of library screening techniques used in the development of dsDNA ligands. Bioorganic & Medicinal Chemistry Letters. 13: 47-50. PMID 12467614 DOI: 10.1016/S0960-894X(02)00836-3 |
0.31 |
|
| 2003 |
Haouz A, Vanheusden V, Munier-Lehmann H, Froeyen M, Herdewijn P, Van Calenbergh S, Delarue M. Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism. The Journal of Biological Chemistry. 278: 4963-71. PMID 12454011 DOI: 10.1074/Jbc.M209630200 |
0.353 |
|
| 2003 |
Vanheusden V, Munier-Lehmann H, Pochet S, Herdewijn P, Van Calenbergh S. Synthesis and evaluation of thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Bioorganic & Medicinal Chemistry Letters. 12: 2695-8. PMID 12217356 DOI: 10.1016/S0960-894X(02)00551-6 |
0.32 |
|
| 2003 |
Wang J, Froeyen M, Herdewijn P. Six-membered Carbocyclic Nucleosides Advances in Antiviral Drug Design. 4: 119-145. DOI: 10.1016/S1075-8593(03)04005-X |
0.329 |
|
| 2003 |
Chaltin P, Borgions F, Rozenski J, Aerschot AV, Herdewijn P. New dsDNA‐Binding Hybrid Molecules Combining an Unnatural Peptide and an Intercalating Moiety Helvetica Chimica Acta. 86: 533-547. DOI: 10.1002/Hlca.200390054 |
0.326 |
|
| 2003 |
Gillaizeau I, Lagoja IM, Nolan SP, Aucagne V, Rozenski J, Herdewijn P, Agrofoglio LA. Straightforward Synthesis of Labeled and Unlabeled Pyrimidine d4Ns via 2′,3′‐Diyne seco Analogues through Olefin Metathesis Reactions European Journal of Organic Chemistry. 2003: 666-671. DOI: 10.1002/Ejoc.200390107 |
0.382 |
|
| 2003 |
Rompaey PV, Nauwelaerts K, Vanheusden V, Rozenski J, Munier‐Lehmann H, Herdewijn P, Calenbergh SV. Mycobacterium tuberculosis Thymidine Monophosphate Kinase Inhibitors: Biological Evaluation and Conformational Analysis of 2′‐ and 3′‐Modified Thymidine Analogues European Journal of Organic Chemistry. 2003: 2911-2918. DOI: 10.1002/Ejoc.200300177 |
0.348 |
|
| 2002 |
Zhang Z, Chaltin P, Aerschot AV, Lacey J, Rozenski J, Busson R, Herdewijn P. New dsDNA binding unnatural oligopeptides with pyrimidine selectivity Bioorganic & Medicinal Chemistry. 10: 3401-3413. PMID 12213453 DOI: 10.1016/S0968-0896(02)00268-7 |
0.32 |
|
| 2002 |
Froeyen M, Herdewijn P. RNA as a target for drug design, the example of Tat-TAR interaction Current Topics in Medicinal Chemistry. 2: 1123-1145. PMID 12173971 DOI: 10.2174/1568026023393200 |
0.317 |
|
| 2002 |
Vastmans K, Rozenski J, Aerschot AV, Herdewijn P. Recognition of HNA and 1,5-anhydrohexitol nucleotides by DNA metabolizing enzymes. Biochimica Et Biophysica Acta. 1597: 115-122. PMID 12009410 DOI: 10.1016/S0167-4838(02)00267-4 |
0.327 |
|
| 2002 |
Van Calenbergh S, Link A, Fujikawa S, De Ligt RAF, Vanheusden V, Golisade A, Blaton NM, Rozenski J, IJzerman AP, Herdewijn P. 5′-deoxy congeners of 9-(3-amido-3-deoxy-β-D-xylofuranosyl)-N6-cyclopentyladenine: New adenosine A1 receptor antagonists and inverse agonists Journal of Medicinal Chemistry. 45: 1845-1852. PMID 11960496 DOI: 10.1021/Jm0110439 |
0.335 |
|
| 2002 |
Gijsbers S, Asselberghs S, Herdewijn P, Veldhoven PPV. 1-O-Hexadecyl-2-desoxy-2-amino-sn-glycerol, a substrate for human sphingosine kinase. Biochimica Et Biophysica Acta. 1580: 1-8. PMID 11923095 DOI: 10.1016/S1388-1981(01)00166-4 |
0.33 |
|
| 2002 |
Verbeure B, Lacey CJ, Froeyen M, Rozenski J, Herdewijn P. Synthesis and cleavage experiments of oligonucleotide conjugates with a diimidazole-derived catalytic center. Bioconjugate Chemistry. 13: 333-50. PMID 11906272 DOI: 10.1021/Bc0155622 |
0.363 |
|
| 2002 |
Sørensen MD, Kvaernø L, Bryld T, Håkansson AE, Verbeure B, Gaubert G, Herdewijn P, Wengel J. alpha-L-ribo-configured locked nucleic acid (alpha-L-LNA): synthesis and properties. Journal of the American Chemical Society. 124: 2164-76. PMID 11878970 DOI: 10.1021/Ja0168763 |
0.316 |
|
| 2002 |
Mikhailov SN, Rozenski J, Efimtseva EV, Busson R, Aerschot AV, Herdewijn P. Chemical incorporation of 1-methyladenosine into oligonucleotides Nucleic Acids Research. 30: 1124-1131. PMID 11861902 DOI: 10.1093/Nar/30.5.1124 |
0.338 |
|
| 2002 |
De Jonghe S, Lamote I, Venkataraman K, Boldin SA, Hillaert U, Rozenski J, Hendrix C, Busson R, De Keukeleire D, Van Calenbergh S, Futerman AH, Herdewijn P. Synthesis of homoceramides, novel ceramide analogues, and their lack of effect on the growth of hippocampal neurons. The Journal of Organic Chemistry. 67: 988-96. PMID 11856049 DOI: 10.1021/Jo011062Q |
0.365 |
|
| 2002 |
Andreeva OI, Golubeva AS, Kochetkov SN, Van Aerschot A, Herdewijn P, Efimtseva EV, Ermolinsky BS, Mikhailov SN. An additional 2′-ribofuranose residue at a specific position of the DNA primer prevents its elongation by HIV-1 reverse transcriptase Bioorganic and Medicinal Chemistry Letters. 12: 681-684. PMID 11844700 DOI: 10.1016/S0960-894X(01)00836-8 |
0.356 |
|
| 2002 |
Declercq R, Van Aerschot A, Read RJ, Herdewijn P, Van Meervelt L. Crystal structure of double helical hexitol nucleic acids. Journal of the American Chemical Society. 124: 928-33. PMID 11829600 DOI: 10.1021/Ja016570W |
0.364 |
|
| 2002 |
Ermolinsky BS, Fomitcheva MV, Efimtseva EV, Mikhailov SN, Esipov DS, Boldyreva EF, Korobko VG, Van Aerschot A, Herdewijn P. Modified oligonucleotides containing 1-β-D-galactopyranosylthymine: Synthesis and substrate properties Bioorganicheskaya Khimiya. 28: 63. DOI: 10.1023/A:1013906303698 |
0.323 |
|
| 2002 |
Chaltin P, Lescrinier E, Lescrinier T, Rozenski J, Hendrix C, Rosemeyer H, Busson R, Aerschot AV, Herdewijn P. Selection of New Sequence‐Selective Unnatural Peptides Binding to Double‐Stranded Deoxyribonucleic Acids (dsDNA) by Means of a Gel‐Retardation Experiment for Library Analysis Helvetica Chimica Acta. 85: 2258-2283. DOI: 10.1002/1522-2675(200208)85:8<2258::Aid-Hlca2258>3.0.Co;2-X |
0.321 |
|
| 2002 |
Herdewijn P. Buchbesprechung: Handbook of Nucleoside Synthesis. Herausgegeben von Helmut Vorbrüggen und Carmen Ruh-Pohlenz Angewandte Chemie. 114: 1693-1694. DOI: 10.1002/1521-3757(20020503)114:9<1693::Aid-Ange1693>3.0.Co;2-G |
0.355 |
|
| 2001 |
Verbeure B, Lescrinier E, Wang J, Herdewijn P. RNase H mediated cleavage of RNA by cyclohexene nucleic acid (CeNA) Nucleic Acids Research. 29: 4941-4947. PMID 11812823 DOI: 10.1093/Nar/29.24.4941 |
0.312 |
|
| 2001 |
Kerremans L, Schepers G, Rozenski J, Busson R, Aerschot aAV, Herdewijn P. Hybridization between "six-membered" nucleic acids: RNA as a universal information system. Organic Letters. 3: 4129-4132. PMID 11784159 DOI: 10.1021/Ol016183R |
0.325 |
|
| 2001 |
Froeyen M, Lescrinier E, Kerremans L, Rosemeyer H, Seela F, Verbeure B, Lagoja I, Rozenski J, Aerschot AV, Busson R, Herdewijn P. α‐Homo‐DNA and RNA Form a Parallel Oriented Non‐A, Non‐B‐Type Double Helical Structure Chemistry: a European Journal. 7: 5183-5194. PMID 11775692 DOI: 10.1002/1521-3765(20011203)7:23<5183::Aid-Chem5183>3.0.Co;2-H |
0.322 |
|
| 2001 |
Wang J, Morral J, Hendrix C, Herdewijn P. A straightforward stereoselective synthesis of D- and L-5-hydroxy-4-hydroxymethyl-2-cyclohexenylguanine Journal of Organic Chemistry. 66: 8478-8482. PMID 11735528 DOI: 10.1021/Jo015924Z |
0.374 |
|
| 2001 |
Aerschot AV, Meldgaard M, Schepers G, Volders F, Rozenski J, Busson R, Herdewijn P. Improved hybridisation potential of oligonucleotides comprising O-methylated anhydrohexitol nucleoside congeners Nucleic Acids Research. 29: 4187-4194. PMID 11600707 DOI: 10.1093/Nar/29.20.4187 |
0.356 |
|
| 2001 |
Wang J, Verbeure B, Luyten I, Froeyen M, Hendrix C, Rosemeyer H, Seela F, Aerschot AV, Herdewijn P. Cyclohexene nucleic acids (CeNA) form stable duplexes with RNA and induce RNase H activity Nucleosides, Nucleotides & Nucleic Acids. 20: 785-788. PMID 11563116 DOI: 10.1081/Ncn-100002430 |
0.337 |
|
| 2001 |
Aerschot AV, Meldgaard M, Volders F, Schepers G, Rozenski J, Herdewijn P. Increased Rna Affinity Of Hna Analogues By Introducing Alkoxy Substituents At The C-1 Or C-3 Position Nucleosides, Nucleotides & Nucleic Acids. 20: 781-784. PMID 11563115 DOI: 10.1081/Ncn-100002429 |
0.315 |
|
| 2001 |
Wang J, Froeyen M, Hendrix C, Andrei C, Snoeck R, Lescrinier E, Clercq ED, Herdewijn P. (D)- and (L)-cyclohexenyl-G, a new class of antiviral agents: synthesis, conformational analysis, molecular modeling, and biological activity. Nucleosides, Nucleotides & Nucleic Acids. 20: 727-730. PMID 11563102 DOI: 10.1081/Ncn-100002360 |
0.35 |
|
| 2001 |
Vastmans K, Froeyen M, Kerremans L, Pochet S, Herdewijn P. Reverse transcriptase incorporation of 1,5-anhydrohexitol nucleotides Nucleic Acids Research. 29: 3154-3163. PMID 11470872 DOI: 10.1093/Nar/29.15.3154 |
0.34 |
|
| 2001 |
Herdewijn P, De Clercq E. The cyclohexene ring as bioisostere of a furanose ring: Synthesis and antiviral activity of cyclohexenyl nucleosides Bioorganic and Medicinal Chemistry Letters. 11: 1591-1597. PMID 11412988 DOI: 10.1016/S0960-894X(01)00270-0 |
0.312 |
|
| 2001 |
Zhang Z, Herdewijn P. Selection of an unnatural peptide library for dsDNA binding Current Medicinal Chemistry. 8: 517-531. PMID 11281839 DOI: 10.2174/0929867003373355 |
0.324 |
|
| 2001 |
Zhang Z, Aerschot AV, Chaltin P, Busson R, Herdewijn P. Epimerization During Coupling to the Unnatural Amino Acid in Solid Phase Peptide Synthesis Collection of Czechoslovak Chemical Communications. 66: 923-932. DOI: 10.1135/Cccc20010923 |
0.333 |
|
| 2001 |
Efimtseva EV, Bobkov GV, Mikhailov SN, Aerschot AV, Schepers G, Busson R, Rozenski J, Herdewijn P. Oligonucleotides Containing Disaccharide Nucleosides Helvetica Chimica Acta. 84: 2387-2397. DOI: 10.1002/1522-2675(20010815)84:8<2387::Aid-Hlca2387>3.0.Co;2-F |
0.354 |
|
| 2001 |
Herdewijn P. TNA as a potential alternative to natural nucleic acids Angewandte Chemie - International Edition. 40: 2249-2251. DOI: 10.1002/1521-3773(20010618)40:12<2249::Aid-Anie2249>3.0.Co;2-I |
0.323 |
|
| 2000 |
Rodionov AA, Efimtseva EV, Mikhailov SN, Rozenski J, Luyten I, Herdewijn P. Synthesis and properties of O-beta-D-ribofuranosyl-(1"-2')-adenosine-5"-O-phosphate and its derivatives. Nucleosides, Nucleotides & Nucleic Acids. 19: 1847-1859. PMID 11200278 DOI: 10.1080/15257770008045465 |
0.328 |
|
| 2000 |
Gritsenko OM, Mikhailov SN, Efimtseva EV, Aerschot AV, Herdewijn P, Gromova ES. Probing the MvaI Methyltransferase Region that Interacts with DNA: Affinity Labeling with the Dialdehyde-Containing DNA Duplexes Nucleosides, Nucleotides & Nucleic Acids. 19: 1805-1820. PMID 11200275 DOI: 10.1080/15257770008045462 |
0.332 |
|
| 2000 |
Van Overmeire I, Boldin SA, Venkataraman K, Zisling R, De Jonghe S, Van Calenbergh S, De Keukeleire D, Futerman AH, Herdewijn P. Synthesis and biological evaluation of ceramide analogues with substituted aromatic rings or an allylic fluoride in the sphingoid moiety. Journal of Medicinal Chemistry. 43: 4189-99. PMID 11063615 DOI: 10.1021/Jm000939V |
0.366 |
|
| 2000 |
Vastmans K, Pochet S, Peys A, Kerremans L, Aerschot AV, Hendrix C, Marlière P, Herdewijn P. Enzymatic incorporation in DNA of 1,5-anhydrohexitol nucleotides. Biochemistry. 39: 12757-12765. PMID 11041840 DOI: 10.1021/Bi001297G |
0.351 |
|
| 2000 |
Herdewijn P. Heterocyclic modifications of oligonucleotides and antisense technology Antisense and Nucleic Acid Drug Development. 10: 297-310. PMID 10984123 DOI: 10.1089/108729000421475 |
0.329 |
|
| 2000 |
Lescrinier E, Esnouf R, Schraml J, Busson R, Heus HA, Hilbers CW, Herdewijn P. Solution structure of a HNA-RNA hybrid Chemistry and Biology. 7: 719-731. PMID 10980452 DOI: 10.1016/S1074-5521(00)00017-X |
0.344 |
|
| 2000 |
Meyermans H, Morreel K, Lapierre C, Pollet B, De Bruyn A, Busson R, Herdewijn P, Devreese B, Van Beeumen J, Marita JM, Ralph J, Chen C, Burggraeve B, Van Montagu M, Messens E, et al. Modifications in lignin and accumulation of phenolic glucosides in poplar xylem upon down-regulation of caffeoyl-coenzyme A O-methyltransferase, an enzyme involved in lignin biosynthesis. The Journal of Biological Chemistry. 275: 36899-909. PMID 10934215 DOI: 10.1074/Jbc.M006915200 |
0.307 |
|
| 2000 |
Kozlov IA, Zielinski M, Allart B, Kerremans L, Van Aerschot A, Busson R, Herdewijn P, Orgel LE. Nonenzymatic template-directed reactions on altritol oligomers, preorganized analogues of oligonucleotides Chemistry - a European Journal. 6: 151-155. PMID 10747399 DOI: 10.1002/(Sici)1521-3765(20000103)6:1<151::Aid-Chem151>3.0.Co;2-H |
0.373 |
|
| 2000 |
Nandanan E, Jang SY, Moro S, Kim HO, Siddiqui MA, Russ P, Marquez VE, Busson R, Herdewijn P, Harden TK, Boyer JL, Jacobson KA. Synthesis, biological activity, and molecular modeling of ribose-modified deoxyadenosine bisphosphate analogues as P2Y(1) receptor ligands. Journal of Medicinal Chemistry. 43: 829-42. PMID 10715151 DOI: 10.1021/Jm990249V |
0.321 |
|
| 2000 |
Wang J, Froeyen M, Hendrix C, Andrei G, Snoeck R, Clercq ED, Herdewijn P. The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine. Journal of Medicinal Chemistry. 43: 736-745. PMID 10691698 DOI: 10.1021/Jm991171L |
0.351 |
|
| 2000 |
Wang J, Verbeure B, Luyten I, Lescrinier E, Froeyen M, Hendrix C, Rosemeyer H, Seela F, Aerschot aAV, Herdewijn P. Cyclohexene Nucleic Acids (CeNA): Serum Stable Oligonucleotides that Activate RNase H and Increase Duplex Stability with Complementary RNA Journal of the American Chemical Society. 122: 8595-8602. DOI: 10.1021/Ja000018+ |
0.362 |
|
| 2000 |
Zhang Z, Aerschot AV, Hendrix C, Busson R, David F, Sandra P, Herdewijn P. Synthesis of Alanine and Proline Amino Acids with Amino or Guanidinium Substitution on the Side Chain Tetrahedron. 56: 2513-2522. DOI: 10.1016/S0040-4020(00)00123-X |
0.364 |
|
| 2000 |
Froeyen M, Wroblowski B, Esnouf R, Winter HD, Allart B, Lescrinier E, Herdewijn P. Molecular-dynamics studies of single-stranded hexitol, altritol, mannitol, and ribose nucleic acids (HNA, MNA, ANA, and RNA, resp.) and of the stability of HNA·RNA, ANA·RNA, and MNA·RNA duplexes Helvetica Chimica Acta. 83: 2153-2182. DOI: 10.1002/1522-2675(20000906)83:9<2153::Aid-Hlca2153>3.0.Co;2-I |
0.344 |
|
| 2000 |
Lescrinier E, Esnouf RM, Schraml J, Busson R, Herdewijn P. Solution Structure of a Hexitol Nucleic Acid Duplex with Four Consecutive T⋅T Base Pairs Helvetica Chimica Acta. 83: 1291-1310. DOI: 10.1002/1522-2675(20000705)83:7<1291::Aid-Hlca1291>3.0.Co;2-T |
0.314 |
|
| 2000 |
Jonghe SD, Overmeire IV, Calenbergh SV, Hendrix C, Busson R, Keukeleire DD, Herdewijn P. Synthesis of fluorinated sphinganine and dihydroceramide analogues. European Journal of Organic Chemistry. 2000: 3177-3183. DOI: 10.1002/1099-0690(200009)2000:18<3177::Aid-Ejoc3177>3.0.Co;2-U |
0.356 |
|
| 2000 |
Boudou V, Langridge J, Aerschot AV, Hendrix C, Millar A, Weiss P, Herdewijn P. Synthesis of the Anticodon HairpintRNAfMet ContainingN-{[9-(β-D-Ribofuranosyl)-9H-purin-6-yl]carbamoyl}-L-threonine (=N6-{{[(1S,2R)-1-Carboxy-2-hydroxypropyl]amino}carbonyl}adenosine, t6A) Helvetica Chimica Acta. 83: 152-161. DOI: 10.1002/(Sici)1522-2675(20000119)83:1<152::Aid-Hlca152>3.0.Co;2-1 |
0.35 |
|
| 1999 |
Kozlov IA, Politis PK, Van Aerschot A, Busson R, Herdewijn P, Orgel LE. Nonenzymatic synthesis of RNA and DNA oligomers on hexitol nucleic acid templates: The importance of the a structure Journal of the American Chemical Society. 121: 2653-2656. PMID 11543583 DOI: 10.1021/Ja983958R |
0.372 |
|
| 1999 |
Kozlov IA, De Bouvere B, Van Aerschot A, Herdewijn P, Orgel LE. Efficient transfer of information from hexitol nucleic acids to RNA during nonenzymatic oligomerization Journal of the American Chemical Society. 121: 5856-5859. PMID 11542282 DOI: 10.1021/Ja990440U |
0.359 |
|
| 1999 |
Kozlov IA, Politis PK, Pitsch S, Herdewijn P, Orgel LE. A highly enantio-selective hexitol nucleic acid template for nonenzymatic oligoguanylate synthesis [11] Journal of the American Chemical Society. 121: 1108-1109. PMID 11541447 DOI: 10.1021/Ja9836489 |
0.388 |
|
| 1999 |
De Jonghe S, Van Overmeire I, Poulton S, Hendrix C, Busson R, Van Calenbergh S, De Keukeleire D, Spiegel S, Herdewijn P. Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase. Bioorganic & Medicinal Chemistry Letters. 9: 3175-80. PMID 10560747 DOI: 10.1016/S0960-894X(99)00554-5 |
0.308 |
|
| 1999 |
De Jonghe S, Van Overmeire I, Gunst J, De Bruyn A, Hendrix C, Van Calenbergh S, Busson R, De Keukeleire D, Philippé J, Herdewijn P. Synthesis and apoptogenic activity of fluorinated ceramide and dihydroceramide analogues. Bioorganic & Medicinal Chemistry Letters. 9: 3159-64. PMID 10560744 DOI: 10.1016/S0960-894X(99)00553-3 |
0.346 |
|
| 1999 |
Mikhailov SN, Rodionov AA, Efimtseva EV, Ermolinsky BS, Fomitcheva MV, Padyukova NS, Rothenbacher K, Lescrinier E, Herdewijn P. Studies on disaccharide nucleoside synthesis. Mechanism of the formation of trisaccharide purine nucleosides Nucleosides and Nucleotides. 18: 691-692. PMID 10432667 DOI: 10.1080/15257779908041543 |
0.353 |
|
| 1999 |
Wouters J, Herdewijn P. 5-substituted pyrimidine 1,5-anhydrohexitols: Conformational analysis and interaction with viral thymidine kinase Bioorganic and Medicinal Chemistry Letters. 9: 1563-1566. PMID 10386936 DOI: 10.1016/S0960-894X(99)00225-5 |
0.302 |
|
| 1999 |
Nandanan E, Camaioni E, Jang SY, Kim YC, Cristalli G, Herdewijn P, Secrist JA, Tiwari KN, Mohanram A, Harden TK, Boyer JL, Jacobson KA. Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists. Journal of Medicinal Chemistry. 42: 1625-38. PMID 10229631 DOI: 10.1021/Jm980657J |
0.316 |
|
| 1999 |
Boudou V, Kerremans L, Bouvere BD, Lescrinier E, Schepers G, Busson R, Aerschot AV, Herdewijn P. Base pairing of anhydrohexitol nucleosides with 2,6-diaminopurine, 5-methylcytosine and uracil as base moiety Nucleic Acids Research. 27: 1450-1456. PMID 10037805 DOI: 10.1093/Nar/27.6.1450 |
0.324 |
|
| 1999 |
Tunitskaya VL, Rusakova EE, Memelova LV, Kochetkov SN, Van Aerschot A, Herdewijn P, Efimtseva EV, Ermolinsky BS, Mikhailov SN. Mapping of T7 RNA polymerase active site with novel reagents - Oligonucleotides with reactive dialdehyde groups Febs Letters. 442: 20-24. PMID 9923596 DOI: 10.1016/S0014-5793(98)01625-1 |
0.328 |
|
| 1999 |
Mikhailov SN, Ermolinsky BS, Efimtseva EV, Moiseyev GP, Tunitskaya VL, Rusakova EE, Kochetkov SN, Gritsenko OM, Gromova ES, Aerschot AV, Herdewijn P. Oligonucleotides containing hexapyranosyl nucleosides and disaccharide nucleosides: Synthesis, incorporation of dialdehyde groups and use as affinity reagents Collection of Czechoslovak Chemical Communications. 2: 141-144. DOI: 10.1135/Css199902141 |
0.352 |
|
| 1999 |
Aerschot AV, Maurinsh Y, Allart B, Boudou V, Herdewijn P. Analogues of hexitol nucleic acids: Structure function relationship of a new steric blocking agent Collection of Czechoslovak Chemical Communications. 2: 100-104. DOI: 10.1135/Css199902100 |
0.302 |
|
| 1999 |
Efimtseva EV, Rodionov AA, Bobkov GV, Ermolinsky BS, Fomitcheva MV, Mikhailov SN, Herdewijn P. Studies on disaccharide nucleoside synthesis Collection of Czechoslovak Chemical Communications. 2: 22-26. DOI: 10.1135/Css199902022 |
0.364 |
|
| 1999 |
Hossain N, Luyten I, Rothenbacher K, Busson R, Herdewijn P. Synthesis and conformational analysis of 1,5-anhydro-2,4-dideoxy-D-mannitol nucleosides Nucleosides, Nucleotides & Nucleic Acids. 18: 161-180. DOI: 10.1080/15257779908043064 |
0.399 |
|
| 1999 |
Busson R, Kerremans L, Aerschot AV, Peeters M, Blaton N, Herdewijn P. Unexpected Shift to a 4-Imino Tautomer Upon N4-Acylation of 5-Methylcytosin-1-yl Nucleoside Analogues Nucleosides, Nucleotides & Nucleic Acids. 18: 1079-1082. DOI: 10.1080/15257779908041652 |
0.364 |
|
| 1999 |
Pochet S, Van Aershot A, Herdewijn P, Marlière P. Replicative capability of anhydrohexitol analogues of nucleotides Nucleosides and Nucleotides. 18: 1015-1017. DOI: 10.1080/15257779908041634 |
0.31 |
|
| 1999 |
Wang J, Herdewijn P. Enantioselective synthesis and conformational analysis of cyclohexene carbocyclic nucleosides Nucleosides and Nucleotides. 18: 593-594. DOI: 10.1080/15257779908041505 |
0.356 |
|
| 1999 |
Wang J, Herdewijn P. A novel and enantioselective approach to the synthesis of cyclohexane carbocyclic nucleosides starting from (-)-carvone Nucleosides and Nucleotides. 18: 591-592. DOI: 10.1080/15257779908041504 |
0.362 |
|
| 1999 |
Boudou V, Rothenbacher K, Van Aerschot A, Herdewijn P. Oligonucleotides with 2,6-diaminopurine base replacing for adenine: Synthesis and properties Nucleosides and Nucleotides. 18: 1429-1431. DOI: 10.1080/07328319908044743 |
0.374 |
|
| 1999 |
Herdewijn P, Allart B, Bouvere BD, Winter HD, Hendrix C, Hossain N, Schepers G, Verheggen I, Wroblowski B, Aerschot AV. Properties of Oligonucleotides with Six Membered Carbohydrate Mimics and a 1,4-Relationship Between the Base Moiety and the Hydroxymethyl Group Nucleosides, Nucleotides & Nucleic Acids. 18: 1371-1376. DOI: 10.1080/07328319908044719 |
0.318 |
|
| 1999 |
Lescrinier E, Sheng S, Schraml J, Busson R, Herdewijn P. d(GCGTAGC), an equilibrium between a hairpin structure and an unusual duplex Nucleosides, Nucleotides & Nucleic Acids. 18: 2721-2744. DOI: 10.1080/07328319908044637 |
0.304 |
|
| 1999 |
Wang J, Herdewijn P. Enantioselective synthesis and conformational study of cyclohexene carbocyclic nucleosides Journal of Organic Chemistry. 64: 7820-7827. DOI: 10.1021/Jo9908288 |
0.349 |
|
| 1999 |
Allart B, Busson R, Rozenski J, Aerschot AV, Herdewijn P. Synthesis of protected D-altritol nucleosides as building blocks for oligonucleotide synthesis Tetrahedron. 55: 6527-6546. DOI: 10.1016/S0040-4020(99)00287-2 |
0.384 |
|
| 1999 |
Maurinsh Y, Rosemeyer H, Esnouf R, Medvedovici A, Wang J, Ceulemans G, Lescrinier E, Hendrix C, Busson R, Sandra P, Seela F, Aerschot AV, Herdewijn P. Synthesis and Pairing Properties of Oligonucleotides Containing 3‐Hydroxy‐4‐hydroxymethyl‐1‐cyclohexanyl Nucleosides Chemistry: a European Journal. 5: 2139-2150. DOI: 10.1002/(Sici)1521-3765(19990702)5:7<2139::Aid-Chem2139>3.0.Co;2-K |
0.381 |
|
| 1998 |
Ostrowski T, Wroblowski B, Busson R, Rozenski J, De Clercq E, Bennett MS, Champness JN, Summers WC, Sanderson MR, Herdewijn P. 5-Substituted pyrimidines with a 1,5-anhydro-2, 3-dideoxy-D-arabino-hexitol moiety at N-1: synthesis, antiviral activity, conformational analysis, and interaction with viral thymidine kinase. Journal of Medicinal Chemistry. 41: 4343-53. PMID 9784109 DOI: 10.1021/Jm980287Z |
0.376 |
|
| 1998 |
Champness JN, Bennett MS, Wien F, Visse R, Summers WC, Herdewijn P, de Clerq E, Ostrowski T, Jarvest RL, Sanderson MR. Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands. Proteins. 32: 350-61. PMID 9715911 DOI: 10.1002/(Sici)1097-0134(19980815)32:3<350::Aid-Prot10>3.0.Co;2-8 |
0.317 |
|
| 1998 |
Basnak I, Sun M, Hamor TA, Focher F, Verri A, Spadari S, Wroblowski B, Herdewijn P, Walker RT. Some 6-aza-5-substituted-2'-deoxyuridines show potent and selective inhibition of herpes simplex virus type 1 thymidine kinase. Nucleosides & Nucleotides. 17: 187-206. PMID 9708347 DOI: 10.1080/07328319808005169 |
0.355 |
|
| 1998 |
Turner S, Herdewijn P. Synthetic strategies towards the synthesis of 1-(2,4-dideoxy-4-C-hydroxymethyl-alpha-L-lyxopyranosyl)base nucleosides Nucleosides, Nucleotides & Nucleic Acids. 17: 2085-2086. DOI: 10.1080/07328319808004750 |
0.322 |
|
| 1998 |
Hossain N, Herdewijn P. Facile synthesis of 3'-C-branched 1,5-anhydrohexitol nucleosides Nucleosides and Nucleotides. 17: 1781-1786. DOI: 10.1080/07328319808004714 |
0.333 |
|
| 1998 |
Hossain N, Herdewijn P. Synthesis of 1,5-anhydro-D-mannitol nucleosides with a purine base moiety Nucleosides and Nucleotides. 17: 1775-1779. DOI: 10.1080/07328319808004713 |
0.328 |
|
| 1998 |
Efimtseva EV, Victorova LS, Rodionov AA, Ermolinsky BS, Fomitcheva MV, Tunitskaya VL, Mikhailov SN, Oivanen M, Van Aerschot A, Herdewijn P. Disaccharide nucleosides and their enzymatic and chemical incorporation into oligonucleotides Nucleosides and Nucleotides. 17: 1681-1684. DOI: 10.1080/07328319808004701 |
0.358 |
|
| 1998 |
Ceulemans G, Van Aerschot A, Herdewijn P. Divers stereoisomers of N-acetylhydroxyprolinol as sugar substitute in oligonucleotides Nucleosides and Nucleotides. 17: 1577-1581. DOI: 10.1080/07328319808004689 |
0.318 |
|
| 1998 |
Allart B, Van Aerschot A, Herdewijn P. 1,5-Anhydro-2-deoxy-D-altritol oligonucleotides as conformationally restricted analogues of RNA Nucleosides and Nucleotides. 17: 1523-1526. DOI: 10.1080/07328319808004682 |
0.37 |
|
| 1998 |
Wang J, Busson R, Blaton N, Rozenski J, Herdewijn P. Enantioselective Approach To The Synthesis Of Cyclohexane Carbocyclic Nucleosides Journal of Organic Chemistry. 63: 3051-3058. DOI: 10.1021/Jo972285C |
0.376 |
|
| 1998 |
Hossain N, Wroblowski B, Aerschot AV, Rozenski J, Bruyn aAD, Herdewijn P. Oligonucleotides Composed of 2‘-Deoxy-1‘,5‘-anhydro-d-mannitol Nucleosides with a Purine Base Moiety Journal of Organic Chemistry. 63: 1574-1582. DOI: 10.1021/Jo9718511 |
0.351 |
|
| 1998 |
De Winter H, Lescrinier E, Van Aerschot A, Herdewijn P. Molecular dynamics simulation to investigate differences in minor groove hydration of HNA/RNA hybrids as compared to HNA/DNA complexes Journal of the American Chemical Society. 120: 5381-5394. DOI: 10.1021/Ja973721F |
0.335 |
|
| 1998 |
Luyten I, Herdewijn P. Hybridization properties of base-modified oligonucleotides within the double and triple helix motif European Journal of Medicinal Chemistry. 33: 515-576. DOI: 10.1016/S0223-5234(98)80016-0 |
0.311 |
|
| 1998 |
Link A, Van Calenbergh S, Herdewijn P. Practical method for the parallel synthesis of 2'-amido-2'- deoxyadenosines Tetrahedron Letters. 39: 5175-5176. DOI: 10.1016/S0040-4039(98)01057-0 |
0.355 |
|
| 1998 |
Hossain N, Halbeek Hv, Clercq ED, Herdewijn P. Corrigendum to “Synthesis of 3′-C-branched 1′,5′-anhydromannitol nucleosides as new antiherpes agents” [Tetrahedron 54 (1998) 2209] Tetrahedron. 54: 5423-5423. DOI: 10.1016/S0040-4020(98)00238-5 |
0.303 |
|
| 1998 |
Hossain N, Van Halbeek H, De Clercq E, Herdewijn P. Synthesis of 3'-C-branched 1',5'-anhydromannitol nucleosides as new antiherpes agents Tetrahedron. 54: 2209-2226. DOI: 10.1016/S0040-4020(97)10431-8 |
0.397 |
|
| 1997 |
Maurinsh Y, Schraml J, Winter HD, Blaton N, Peeters O, Lescrinier E, Rozenski J, Aerschot AV, Clercq ED, Busson R, Herdewijn P. Synthesis and Conformational Study of 3-Hydroxy-4-(Hydroxymethyl)-1-Cyclohexanyl Purines and Pyrimidines. Journal of Organic Chemistry. 62: 2861-2871. PMID 11671649 DOI: 10.1021/Jo962204X |
0.377 |
|
| 1997 |
Hossain N, Rozenski J, Clercq ED, Herdewijn P. Synthesis and Antiviral Activity of the alpha-Analogues of 1,5-Anhydrohexitol Nucleosides (1,5-Anhydro-2,3-dideoxy-D-ribohexitol Nucleosides). Journal of Organic Chemistry. 62: 2442-2447. PMID 11671579 DOI: 10.1021/Jo961982M |
0.369 |
|
| 1997 |
Brevnov MG, Gritsenko OM, Mikhailov SN, Efimtseva EV, Ermolinsky BS, Van Aerschot A, Herdewijn P, Repyk AV, Gromova ES. DNA duplexes with reactive dialdehyde groups as novel reagents for cross-linking to restriction-modification enzymes Nucleic Acids Research. 25: 3302-3309. PMID 9241245 DOI: 10.1093/Nar/25.16.3302 |
0.324 |
|
| 1997 |
Marangoni M, Aerschot AV, Augustyns P, Rozenski J, Herdewijn P. Synthesis and hybridization properties of inverse oligonucleotides Nucleic Acids Research. 25: 3034-3041. PMID 9224602 DOI: 10.1093/Nar/25.15.3034 |
0.361 |
|
| 1997 |
Saeyens W, De Keukeleire D, Herdewijn P, De Bruyn A. Access to sterically confined nucleoside analogues via intramolecular photocycloadditions of arene-alkene trichromophores. Biomedical Chromatography : Bmc. 11: 79-80. PMID 9137762 DOI: 10.1002/(Sici)1099-0801(199703)11:2<79::Aid-Bmc644>3.0.Co;2-A |
0.347 |
|
| 1997 |
Samson I, Rozenski J, Samyn B, Van Aerschot A, Van Beeumen J, Herdewijn P. Screening a random pentapeptide library, composed of 14 D-amino acids, against the COOH-terminal sequence of fructose-1,6-bisphosphate aldolase from Trypanosoma brucei Journal of Biological Chemistry. 272: 11378-11383. PMID 9111046 DOI: 10.1074/Jbc.272.17.11378 |
0.302 |
|
| 1997 |
De Bruyn A, Maras M, Schraml J, Herdewijn P, Contreras R. NMR evidence for a novel asparagine-linked oligosaccharide on cellobiohydrolase I from Trichoderma reesei RUTC 30. Febs Letters. 405: 111-3. PMID 9094436 DOI: 10.1016/S0014-5793(97)00146-4 |
0.301 |
|
| 1997 |
Luyten I, Vanaerschot A, Rozenski J, Busson R, Herdewijn P. Protection of 2,6-Diaminopurine 2′-Deoxyriboside Nucleosides, Nucleotides & Nucleic Acids. 16: 1649-1652. DOI: 10.1080/07328319708006247 |
0.33 |
|
| 1997 |
DeBouvere B, Kerremans L, Hendrix C, DeWinter H, Schepers G, Vanaerschot A, Herdewijn P. Hexitol Nucleic Acids (HNA): Synthesis and Properties Nucleosides, Nucleotides & Nucleic Acids. 16: 973-976. DOI: 10.1080/07328319708006119 |
0.388 |
|
| 1997 |
Mikhailov SN, Efimtseva EV, Gurskaya GV, Fomitcheva MV, Meshkov SV, Zavodnik VE, Bruyn AD, Janssen G, Rozenski J, Herdewijn P. An Efficient Synthesis And Physico-Chemical Properties Of 2'-O-D-Ribofuranosylnucleosides, Minor Trna Components Journal of Carbohydrate Chemistry. 16: 75-92. DOI: 10.1080/07328309708006511 |
0.339 |
|
| 1997 |
Saeyens W, Busson R, Eycken JVd, Herdewijn P, Keukeleire DD. Fully Selective Intramolecular Ortho Photocycloaddition Of 4-(4-Methoxy-Phenoxy)-3-(N3-Benzoylthymin-1-Yl)But-1-Ene: An Unprecedented Benzene-Thymine Photocycloaddition Chemical Communications. 817-818. DOI: 10.1039/A700554G |
0.308 |
|
| 1997 |
Polak M, Doboszewski B, Herdewijn P, Plavec J. Conformational studies on 2',3'-unsaturated pentopyranosyl nucleosides by 1H NMR spectroscopy. Impact of π → σ* interactions on the axial preference of the purine versus pyrimidine nucleobase Journal of the American Chemical Society. 119: 9782-9792. DOI: 10.1021/Ja963683K |
0.317 |
|
| 1997 |
Herdewijn P. Structural requirements for antiviral activity in nucleosides Drug Discovery Today. 2: 235-242. DOI: 10.1016/S1359-6446(97)01047-7 |
0.318 |
|
| 1997 |
Ceulemans G, Aerschot AV, Rozenski J, Herdewijn P. Oligonucleotides with 3-hydroxy-N-acetylprolinol as sugar substitute Tetrahedron. 53: 14957-14974. DOI: 10.1016/S0040-4020(97)01047-8 |
0.326 |
|
| 1997 |
Bouvere BD, Kerremans L, Rozenski J, Janssen G, Aerschot Av, Claes P, Busson R, Herdewijn P. Improved Synthesis of Anhydrohexitol Building Blocks for Oligonucleotide Synthesis Liebigs Annalen. 1997: 1453-1461. DOI: 10.1002/Jlac.199719970724 |
0.379 |
|
| 1997 |
Ceulemans G, Aerschot AV, Wroblowski B, Rozenski J, Hendrix C, Herdewijn P. Oligonucleotide analogues with 4-hydroxy-N-acetylprolinol as sugar substitute Chemistry: a European Journal. 3: 1997-2010. DOI: 10.1002/Chem.19970031215 |
0.339 |
|
| 1997 |
Hendrix C, Rosemeyer H, Bouvere BD, Aerschot AV, Seela F, Herdewijn P. 1',5'-anhydrohexitol oligonucleotides: Hybridisation and strand displacement with oligoribonucleotides, interaction with RNase H and HIV reverse transcriptase Chemistry: a European Journal. 3: 1513-1520. DOI: 10.1002/Chem.19970030920 |
0.319 |
|
| 1997 |
Hendrix C, Rosemeyer H, Verheggen I, Aerschot AV, Seela F, Herdewijn P. 1′, 5′ ‐Anhydrohexitol Oligonucleotides: Synthesis, Base Pairing and Recognition by Regular Oligodeoxyribonucleotides and Oligoribonucleotides Chemistry: a European Journal. 3: 110-120. DOI: 10.1002/Chem.19970030118 |
0.367 |
|
| 1996 |
De Winter H, Herdewijn P. Understanding the binding of 5-substituted 2′-deoxyuridine substrates to thymidine kinase of herpes simplex virus type-1 Journal of Medicinal Chemistry. 39: 4727-4737. PMID 8941385 DOI: 10.1021/Jm960278V |
0.358 |
|
| 1996 |
Creuven I, Evrard C, Olivier A, Evrard G, Aerschot AV, Wigerinck P, Herdewijn P, Durant F. Relationship between structural properties and affinity for herpes simplex virus type 1 thymidine kinase of bromine substituted 5-heteroaromatic 2′-deoxyuridines Antiviral Research. 30: 63-74. PMID 8783799 DOI: 10.1016/0166-3542(95)00838-1 |
0.328 |
|
| 1996 |
Efimtseva EV, Ermolinsky BS, Fomitcheva MV, Meshkov SV, Padyukova NS, Mikhailov SN, Aerschot AV, Rozenski J, Herdewijn P. Synthesis of disaccharide nucleosides and their incorporation into oligonucleotides Collection of Czechoslovak Chemical Communications. 61: 206-209. DOI: 10.1135/Cccc1996S206 |
0.378 |
|
| 1996 |
Declercq R, Herdewijn P, Van Meervelt L. 1,5-anhydro-2,3-dideoxy-2-(guanin-9-yl)-D-arabino-hexitol Acta Crystallographica Section C: Crystal Structure Communications. 52: 1213-1215. DOI: 10.1107/S0108270195015101 |
0.301 |
|
| 1996 |
Verheggen I, Aerschot AV, Rozenski J, Janssen G, Clercq ED, Herdewijn P. Synthesis of 1,5-Anhydrohexitol Nucleosides as Mimics of AZT, D4T and DDC + Nucleosides, Nucleotides & Nucleic Acids. 15: 325-335. DOI: 10.1080/07328319608002387 |
0.329 |
|
| 1996 |
Mikhailov SN, Blaton N, Rozenski J, Balzarini J, Clercq ED, Herdewijn P. Use of Cyclohexene Epoxides in the Preparation of Carbocyclic Nucleosides Nucleosides, Nucleotides & Nucleic Acids. 15: 867-878. DOI: 10.1080/07328319608002133 |
0.308 |
|
| 1996 |
Hossain N, Hendrix C, Lescrinier E, Aerschot AV, Busson R, Clercq ED, Herdewijn P. Homo-N-nucleosides: Incorporation into oligonucleotides and antiviral activity Bioorganic & Medicinal Chemistry Letters. 6: 1465-1468. DOI: 10.1016/S0960-894X(96)00254-5 |
0.339 |
|
| 1996 |
Pérez-Pérez M, Clercq ED, Herdewijn P. Synthesis and antiviral activity of 2-deoxy-1,5-anhydro-D-mannitol nucleosides containing a pyrimidine base moiety Bioorganic & Medicinal Chemistry Letters. 6: 1457-1460. DOI: 10.1016/S0960-894X(96)00244-2 |
0.384 |
|
| 1996 |
Andersen MW, Daluge SM, Kerremans L, Herdewijn P. The synthesis of modified D- and L-anhydrohexitol nucleosides Tetrahedron Letters. 37: 8147-8150. DOI: 10.1016/0040-4039(96)01895-3 |
0.326 |
|
| 1996 |
Hossain N, Rozenski J, De Clercq E, Herdewijn P. Synthesis and antiviral activity of acyclic analogues of 1,5-anhydrohexitol nucleosides using Mitsunobu reaction Tetrahedron. 52: 13655-13670. DOI: 10.1016/0040-4020(96)00818-6 |
0.371 |
|
| 1996 |
Luyten I, Herdewijn P. Synthesis and conformational behavior of purine and pyrimidine β-D-threo-hex-3'-enopyranosyl nucleosides Tetrahedron. 52: 9249-9262. DOI: 10.1016/0040-4020(96)00474-7 |
0.329 |
|
| 1996 |
Lescrinier T, Busson R, Rozenski J, Janssen G, Aerschot AV, Herdewijn P. Incorporation of 5-hydroxytryptophan in oligopeptides Tetrahedron. 52: 6965-6972. DOI: 10.1016/0040-4020(96)00301-8 |
0.347 |
|
| 1996 |
Doboszewski B, Herdewijn P. Branched-chain nucleosides : Synthesis of 3′-deoxy-3′-C-hydroxymethyl-α-L-lyxopyranosyl thymine and 3′-deoxy-3′-C-hydroxymethyl-α-L-threofuranosyl thymine Tetrahedron. 52: 1651-1668. DOI: 10.1016/0040-4020(95)00994-9 |
0.329 |
|
| 1996 |
Creuven I, Norberg B, Olivier A, Evrard C, Evrard G, Wigerinck P, Herdewijn P, Durant F. 5-(thien-2-yl) uracil analogs: 5-(5-methylthien-2-yl)-2′-deoxyuridine, 5-(5-thien-2-yl)-2′-deoxyuridine, and 5-(5-bromothien-2-yl)-2′-deoxyuridine Journal of Chemical Crystallography. 26: 777-789. DOI: 10.1007/Bf01664656 |
0.32 |
|
| 1996 |
Herdewijn P. Targeting RNA with conformationally restricted oligonucleotides Liebigs Annales. 1337-1348. DOI: 10.1002/Jlac.199619960902 |
0.323 |
|
| 1996 |
Luyten I, Winter HD, Busson R, Lescrinier T, Creuven I, Durant F, Balzarini J, Clercq ED, Herdewijn P. Synthesis of 2′‐Deoxy‐5‐(isothiazol‐5‐yl)uridine and Its Interaction with the HSV‐1 Thymidine Kinase Helvetica Chimica Acta. 79: 1462-1474. DOI: 10.1002/Hlca.19960790519 |
0.363 |
|
| 1995 |
Hendrix C, Devreese B, Rozenski J, van Aerschot A, De Bruyn A, Van Beeumen J, Herdewijn P. Incorporation of 2'-amido-nucleosides in oligodeoxynucleotides and oligoribonucleotides as a model for 2'-linked conjugates. Nucleic Acids Research. 23: 51-7. PMID 7870590 DOI: 10.1093/Nar/23.1.51 |
0.348 |
|
| 1995 |
Hendrix C, Mahieu M, Anné J, Van Calenbergh S, Van Aerschot A, Content J, Herdewijn P. Catalytic activity and stability of hammerhead ribozymes containing 2'-acetamido-2'-deoxyribonucleosides. Biochemical and Biophysical Research Communications. 210: 67-73. PMID 7741750 DOI: 10.1006/Bbrc.1995.1628 |
0.323 |
|
| 1995 |
Van Calenbergh S, Verlinde CL, Soenens J, De Bruyn A, Callens M, Blaton NM, Peeters OM, Rozenski J, Hol WG, Herdewijn P. Synthesis and structure-activity relationships of analogs of 2'-deoxy-2'-(3-methoxybenzamido)adenosine, a selective inhibitor of trypanosomal glycosomal glyceraldehyde-3-phosphate dehydrogenase. Journal of Medicinal Chemistry. 38: 3838-49. PMID 7562915 DOI: 10.1021/Jm00019A014 |
0.353 |
|
| 1995 |
Aerschot AV, Rozenski J, Loakes D, Pillet N, Schepers G, Herdewijn P. An acyclic 5-nitroindazole nucleoside analogue as ambiguous nucleoside Nucleic Acids Research. 23: 4363-4370. PMID 7501457 DOI: 10.1093/Nar/23.21.4363 |
0.399 |
|
| 1995 |
Luyten I, Jie L, Van Aerschot A, Pannecouque C, Wigerinck P, Rozenski J, Hendrix C, Wang C, Wiebe L, Balzarini J, De Clercq E, Herdewijn P. 2′-Deoxyuridines with a 5-Heteroaromatic Substituent: Synthesis and Biological Evaluation Antiviral Chemistry and Chemotherapy. 6: 262-270. DOI: 10.1177/095632029500600409 |
0.399 |
|
| 1995 |
Ceulemans G, Vandendriessche F, Rozenski J, Herdewijn P. Synthesis of an Uncharged Camp-Analogue Nucleosides and Nucleotides. 14: 117-127. DOI: 10.1080/15257779508014657 |
0.318 |
|
| 1995 |
Aerschot AV, Hendrix C, Schepers G, Pillet N, Herdewijn P. In Search of Acyclic Analogues as Universal Nucleosides in Degenerate Probes Nucleosides, Nucleotides & Nucleic Acids. 14: 1053-1056. DOI: 10.1080/15257779508012532 |
0.38 |
|
| 1995 |
Pannecouque C, Rozenski J, Devreese B, Beeumen JV, Aerschot AV, Herdewijn P. The N1-(3′-Deoxythymidin-3′-yl)-N2-cyano-N3-(5′-deoxythymidin-5′-yl) Guanidine Dimeric Building Block in Automated DNA Synthesis and Mass Spectrometric Analysis of Its Integrity Nucleosides, Nucleotides & Nucleic Acids. 14: 1037-1040. DOI: 10.1080/15257779508012528 |
0.322 |
|
| 1995 |
Ceulemans G, Khan K, Schepdael AV, Herdewijn P. Peptide analogues of dna consisting of L-α-amino-ϒ-thymine butyric acid and l-valine subunits Nucleosides and Nucleotides. 14: 813-816. DOI: 10.1080/15257779508012478 |
0.323 |
|
| 1995 |
Pannecouque C, Poppel KV, Balzarini J, Claes P, Clercq ED, Herdewijn P. Synthesis and Antiviral Evaluation of 3′-Substituted Thymidine Analogues Derived from 3′-Amino-3′-deoxythymidine Nucleosides, Nucleotides & Nucleic Acids. 14: 541-544. DOI: 10.1080/15257779508012422 |
0.371 |
|
| 1995 |
Liu J, Aerschot AV, Luyten I, Wigerinck P, Pannecouque C, Balzarini J, Clercq ED, Herdewijn P. Synthesis and Antiviral Activities of Some New 5-Heteroaromatic Substituted Derivatives of 2′-Deoxyuridine Nucleosides, Nucleotides & Nucleic Acids. 14: 525-528. DOI: 10.1080/15257779508012418 |
0.379 |
|
| 1995 |
Sergey NM, De Bruyn A, Herdewijn P. Synthesis and properties of some 2!-O-D-Ribofuranosyl-Nucleosides Nucleosides and Nucleotides. 14: 481-484. DOI: 10.1080/15257779508012410 |
0.303 |
|
| 1995 |
Verheggen I, Van Aerschot A, Pillet N, van der Wenden EM, Ijzerman A, Herdewijn P. Synthesis of 1,5-Anhydro-2-(N6-Cyclopentyladenin-9-Yl)-2-Deoxy-D-Altrohexitol Nucleosides, Nucleotides and Nucleic Acids. 14: 321-324. DOI: 10.1080/15257779508012372 |
0.348 |
|
| 1995 |
Thoithi G, Schepdael AV, Busson R, Herdewijn P, Roets E, Hoogmartens J. Evaluation of the Kinetics of Hydrolysis of Monoamino Analogues of 2′- or 3′-Deoxyadenosine and of 9-(2-Deoxy-β-D-Threo-pentofuranosyl)Adenine or 9-(3-Deoxy-β-D-threo-pentofuranosyl)Adenine by Liquid Chromatography Nucleosides, Nucleotides & Nucleic Acids. 14: 1559-1579. DOI: 10.1080/15257779508009492 |
0.336 |
|
| 1995 |
Pérez-Pérez MJ, Rozenski J, Busson R, Herdewijn P. Application of the mitsunobu-type condensation reaction to the synthesis of phosphonate derivatives of cyclohexenyl and cyclohexanyl nucleosides Journal of Organic Chemistry. 60: 1531-1537. DOI: 10.1021/Jo00111A010 |
0.347 |
|
| 1995 |
Pérez-Pérez M, Balzarini J, Rozenski J, Clercq ED, Herdewijn P. Synthesis and antiviral activity of phosphonate derivatives of enantiomeric dihydro-2H-pyranyl nucleosides. Bioorganic & Medicinal Chemistry Letters. 5: 1115-1118. DOI: 10.1016/0960-894X(95)00176-T |
0.358 |
|
| 1995 |
Pérez-Pérez MJ, Doboszewski B, Rozenski J, Herdewijn P. Stereocontrolled synthesis of phosphonate derivatives of tetrahydro- and dihydro-2H-pyranyl nucleosides: The selectivity of the Ferrier rearrangement Tetrahedron: Asymmetry. 6: 973-984. DOI: 10.1016/0957-4166(95)00108-2 |
0.315 |
|
| 1995 |
Doboszewski B, Blaton N, Herdewijn P. Synthesis of β configured 2′,3′-unsaturated pentopyranosyl nucleosides Tetrahedron Letters. 36: 1321-1324. DOI: 10.1016/0040-4039(94)02466-O |
0.355 |
|
| 1995 |
Doboszewski B, De Winter H, Van Aerschot A, Herdewijn P. Synthesis of 3′-Deoxy-3′-C-Hydroxymethyl-aldopentopyranosyl Nucleosides and their Incorporation in Oligonucleotides. Part II 1 Tetrahedron. 51: 12319-12336. DOI: 10.1016/0040-4020(95)00777-6 |
0.362 |
|
| 1995 |
Doboszewski B, Blaton N, Rozenski J, Bruyn AD, Herdewijn P. 3′-Deoxy-3′-hydroxymethyl-aldopentopyranosyl nucleoside synthesis. Part I Tetrahedron. 51: 5381-5396. DOI: 10.1016/0040-4020(95)00211-P |
0.342 |
|
| 1995 |
Pannecouque C, Busson R, Balzarini J, Claes P, Clercq ED, Herdewijn P. Synthesis and antiviral evaluation of 3′-substituted thymidine analogues derived from 3′-amino-3′-deoxythymidine Tetrahedron. 51: 5369-5380. DOI: 10.1016/0040-4020(95)00198-H |
0.394 |
|
| 1995 |
Samson I, Rozenski J, van Aerschot A, Samyn B, van Beeumen J, Herdewijn P. Screening of a synthetic pentapeptide library composed of d-amino acids against fructose-1,6-biphosphate aldolase Letters in Peptide Science. 2: 259-260. DOI: 10.1007/Bf00119166 |
0.318 |
|
| 1995 |
Lescrinier T, Busson R, Rozenski J, Aerschot Av, Herdewijn P. 5-Hydroxytryptophan as a building block in oligopeptides using Fmoc/tBu SPPS Letters in Peptide Science. 2: 225-228. DOI: 10.1007/Bf00119159 |
0.369 |
|
| 1995 |
Samson I, van Aerschot A, Samyn B, van Beeumen J, Herdewijn P. Screening of a synthetic peptide library against glycosomal phosphoglycerate kinase of Trypanosoma brucei Letters in Peptide Science. 2: 217-219. DOI: 10.1007/Bf00119157 |
0.307 |
|
| 1995 |
Lescrinier T, Pannecouque C, Rozenski J, Aerschot Av, Herdewijn P. Amino acids derived from ornithine Letters in Peptide Science. 2: 206-208. DOI: 10.1007/Bf00119154 |
0.325 |
|
| 1994 |
Olivier A, Creuven I, Evrard C, Evrard G, Dory M, Aerschot Av, Wigerinck P, Herdewijn P, Durant F. Stereoelectronic properties of five anti-HSV-1, 2'-deoxynucleosides analogues with heterocyclic substituents in the 5-position : a comparison with BVDU Antiviral Research. 24: 289-304. PMID 7993074 DOI: 10.1016/0166-3542(94)90076-0 |
0.324 |
|
| 1994 |
Ceulemans G, Busson R, Weyns N, Vandendriessche F, Rozenski J, IJzerman A, Herdewijn P. Synthesis of 3′-Fluoro-3′-deoxy-N6-cyclopentyladenosine Nucleosides and Nucleotides. 13: 1991-2000. DOI: 10.1080/15257779408010677 |
0.365 |
|
| 1994 |
Aerschot AV, Ni Z, Rozenski J, Claes P, Clercq ED, Herdewijn P. 2-Hydroxyethoxyethylated Bases as Acyclic Analogues of 1,5-Anhydrohexitol Nucleoside Derivatives Nucleosides, Nucleotides & Nucleic Acids. 13: 1791-1800. DOI: 10.1080/15257779408009481 |
0.404 |
|
| 1994 |
Herdewijn P, Bruyn AD, Wigerinck P, Hendrix C, Kerremans L, Rozenski J, Busson R. Synthesis of 3′-fluoromethylthio-, 3′-fluoromethylsulfinyl- and 3′-fluoromethylsulfonyl-substituted 3′-deoxythymidine Journal of the Chemical Society-Perkin Transactions 1. 249-255. DOI: 10.1039/P19940000249 |
0.355 |
|
| 1994 |
Pannecouque C, Schepers G, Rozenski J, Aerschot AV, Claes P, Herdewijn P. Mixed oligonucleotide analogues with an acyclic carbohydrate moiety and a N-cyanoguanidine functionality Bioorganic & Medicinal Chemistry Letters. 4: 1203-1206. DOI: 10.1016/S0960-894X(01)80330-9 |
0.33 |
|
| 1994 |
Pérez-Pérez MJ, Rozenski J, Herdewijn P. Stereospecific synthesis of a pentopyranosyl analogue of d4T monophosphate Bioorganic and Medicinal Chemistry Letters. 4: 1199-1202. DOI: 10.1016/S0960-894X(01)80329-2 |
0.374 |
|
| 1994 |
Pannecouque C, Vandendriessche F, Rozenski J, Janssen G, Busson R, Aerschot AV, Claes P, Herdewijn P. Synthesis, enzymatic stability and physicochemical properties of oligonucleotides containing a N-cyanoguanidine linkage. Tetrahedron. 50: 7231-7246. DOI: 10.1016/S0040-4020(01)85246-7 |
0.359 |
|
| 1994 |
Augustyns K, Rozenski J, Aerschot AV, Busson R, Claes P, Herdewijn P. Synthesis of a new branched chain hexopyranosyl nucleoside: 1-[2′,3′-dideoxy-3′-C-(hydroxymethyl)-α-D-erythro-pentopyranosyl]-thymine Tetrahedron. 50: 1189-1198. DOI: 10.1016/S0040-4020(01)80830-9 |
0.371 |
|
| 1994 |
Van Calenbergh S, Van Den Eeckhout E, Herdewijn P, De Bruyn A, Verlinde C, Hol W, Callens M, Van Aerschot A, Rozenski J. Synthesis and Conformational Analysis of 2?-Deoxy-2?-(3-methoxybenzamido)adenosine, a rational-designed inhibitor of trypanosomal glyceraldehyde phosphate dehydrogenase (GAPDH) Helvetica Chimica Acta. 77: 631-644. DOI: 10.1002/Hlca.19940770306 |
0.349 |
|
| 1993 |
Verheggen I, Aerschot AV, Toppet S, Snoeck R, Janssen G, Balzarini J, Clercq ED, Herdewijn P. Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides. Journal of Medicinal Chemistry. 36: 2033-2040. PMID 8393114 DOI: 10.1021/Jm00066A013 |
0.336 |
|
| 1993 |
Augustyns K, Godard G, Hendrix C, Van Aerschot A, Rozenski J, Saison-Behmoaras T, Herdewijn P. Hybridization specificity, enzymatic activity and biological (Ha-ras) activity of oligonucleotides containing 2,4-dideoxy-beta-D-erythro-hexopyranosyl nucleosides. Nucleic Acids Research. 21: 4670-6. PMID 7694231 DOI: 10.1093/Nar/21.20.4670 |
0.31 |
|
| 1993 |
Everaert DH, Peeters OM, Ranter CJD, Blaton NM, Aerschot Av, Herdewijn P. Conformational analysis of substituent effects on the sugar puckering mode and the anti-HIV activity of 2',3'-dideoxypyrimidine nucleosides Antiviral Chemistry & Chemotherapy. 4: 289-299. DOI: 10.1177/095632029300400505 |
0.317 |
|
| 1993 |
Pannecouque C, Poppel KV, Aerschot AV, Herdewijn P. Synthesis and physicochemical properties of oligonucleotides with an N -cyanoguanidine function instead of the natural phosphate internucleotide linkage Collection of Czechoslovak Chemical Communications. 58: 191-194. DOI: 10.1135/Cccc1993S191 |
0.312 |
|
| 1993 |
Verheggen I, Pillet N, Aerschot AV, Clercq ED, Herdewijn P. Synthesis and anti-herpesvirus activity of nucleosides with a 1,5'-anhydrohexitol moiety Collection of Czechoslovak Chemical Communications. 58: 64-67. DOI: 10.1135/Cccc1993S064 |
0.338 |
|
| 1993 |
Van Calenbergh S, Verlinde C, De Bruyn A, Callens M, Van Den Eeckhout E, Van Aerschot A, Michels P, Opperdoes F, Hol W, Herdewijn P. 2'-Substituted adenosine analogues as trypanosomal glyceraldehyde phosphate dehydrogenase (GAPDH) inhibitors Collection of Czechoslovak Chemical Communications. 58: 52-55. DOI: 10.1135/Cccc1993S052 |
0.322 |
|
| 1993 |
Vandendriessche F, Aerschot AV, Voortmans M, Janssen G, Busson R, Overbeke AV, Bossche WVd, Hoogmartens J, Herdewijn P. Synthesis, enzymatic stability and base-pairing properties of oligothymidylates containing thymidine dimers with different N-substituted guanidine linkages Journal of the Chemical Society-Perkin Transactions 1. 1567-1575. DOI: 10.1039/P19930001567 |
0.384 |
|
| 1993 |
Augustyns K, Rozenski J, Van Aerschot A, Janssen G, Herdewijn P. Synthesis of 2,4-dideoxy-.beta.-D-erythro-hexopyranosyl nucleosides The Journal of Organic Chemistry. 58: 2977-2982. DOI: 10.1021/Jo00063A013 |
0.345 |
|
| 1993 |
Vandendriessche F, Voortmans M, Hoogmartens J, Aerschot AV, Herdewijn P. Synthesis of Novel N-substituted guanidine linked nucleoside dimers and their incorporation into oligonucleotides Bioorganic & Medicinal Chemistry Letters. 3: 193-198. DOI: 10.1016/S0960-894X(01)80875-1 |
0.336 |
|
| 1993 |
Van Aerschot A, Verheggen I, Herdewijn P. Synthesis of nucleoside analogues with a 1,5-anhydrohexitol moiety Bioorganic and Medicinal Chemistry Letters. 3: 1013-1018. DOI: 10.1016/S0960-894X(00)80278-4 |
0.361 |
|
| 1993 |
Vandendriessche F, Augustyns K, Van Aerschot A, Busson R, Hoogmartens J, Herdewijn P. Acyclic oligonucleotides: possibilities and limitations Tetrahedron. 49: 7223-7238. DOI: 10.1016/S0040-4020(01)87200-8 |
0.316 |
|
| 1992 |
Augustyns K, Vandendriessche F, Van Aerschot A, Busson R, Urbanke C, Herdewijn P. Incorporation of hexose nucleoside analogues into oligonucleotides: Synthesis, base-pairing properties and enzymatic stability Nucleic Acids Research. 20: 4711-4716. PMID 1329028 DOI: 10.1093/Nar/20.18.4711 |
0.331 |
|
| 1992 |
Vandendriessche F, Snoeck R, Janssen G, Hoogmartens J, Aerschot AV, Clercq ED, Herdewijn P. Synthesis and antiviral activity of acyclic nucleosides with a 3(S),5-dihydroxypentyl or 4(R)-methoxy-3(S),5-dihydroxypentyl side chain. Journal of Medicinal Chemistry. 35: 1458-1465. PMID 1315394 DOI: 10.1021/Jm00086A015 |
0.324 |
|
| 1992 |
Herdewijn P, Kerremans L, Snoeck R, Van AA, Esmans E, De Clercq E. Synthesis and anti-herpes activity of 5-trifluorovinyl-2′-deoxyuridine Bioorganic & Medicinal Chemistry Letters. 2: 1057-1062. DOI: 10.1016/S0960-894X(00)80618-6 |
0.355 |
|
| 1992 |
Pannecouque C, Wigerinck P, Van Aerschot A, Herdewijn P. Dimeric building blocks with N-cyanoguanidine linkage for oligonucleotide synthesis Tetrahedron Letters. 33: 7609-7612. DOI: 10.1016/S0040-4039(00)60837-7 |
0.36 |
|
| 1992 |
Oksman P, Hakala H, Zavgorodny S, Polianski M, Azhayev A, Aerschot Av, Herdewijn P, Lönnberg H. Solution conformations and hydrolytic stability of 2′ ‐ and 3′ ‐substituted 2′,3′‐dideoxyribonucleosides, including some potential inhibitors of human immunodeficiency virus Journal of Physical Organic Chemistry. 5: 741-747. DOI: 10.1002/Poc.610051106 |
0.355 |
|
| 1992 |
Augustyns K, van Aerschot A, Urbanke C, Herdewijn P. Influence of the Incorporation of 1‐(2,3‐Dideoxy‐β‐D‐Erythro‐Hexopyranosyl)‐Thymine on the Enzymatic Stability and Base‐Pairing Properties of Oligodeoxynucleotides Bulletin Des SociéTéS Chimiques Belges. 101: 119-130. DOI: 10.1002/Bscb.19921010207 |
0.368 |
|
| 1991 |
Wigerinck P, Snoeck R, Claes P, Clercq ED, Herdewijn P. Synthesis and antiviral activity of 5-heteroaryl-substituted 2'-deoxyuridines. Journal of Medicinal Chemistry. 34: 1767-1772. PMID 2061920 DOI: 10.1021/Jm00110A003 |
0.351 |
|
| 1991 |
Augustyns K, Van Aerschot A, Van Schepdael A, Urbanke C, Herdewijn P. Influence of the incorporation of (S)-9-(3,4-dihydroxybutyl) adenine on the enzymatic stability and base-pairing properties of oligodeoxynucleotides Nucleic Acids Research. 19: 2587-2593. PMID 2041735 DOI: 10.1093/Nar/19.10.2587 |
0.321 |
|
| 1991 |
Balzarini J, Holy A, Jindrich J, Dvorakova H, Hao Z, Snoeck R, Herdewijn P, Johns DG, Clercq ED. 9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 88: 4961-4965. PMID 1711214 DOI: 10.1073/Pnas.88.11.4961 |
0.325 |
|
| 1991 |
Balzarini J, Hao Z, Herdewijn P, Johns DG, Clercq ED. Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound. Proceedings of the National Academy of Sciences of the United States of America. 88: 1499-1503. PMID 1705039 DOI: 10.1073/Pnas.88.4.1499 |
0.323 |
|
| 1991 |
Wigerinck P, Pannecouque C, Snoeck R, Claes P, Clercq ED, Herdewijn P. 5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication. Journal of Medicinal Chemistry. 34: 2383-2389. PMID 1652017 DOI: 10.1021/Jm00112A011 |
0.336 |
|
| 1991 |
Herdewijn P, Aerschot AV, Busson R, Claes P, Clercq ED. Synthesis of 2′-Deoxy-2′ -Fluoro-D-Arabinopyranopyranosyl Nucleosides and Their 3′,4′-Seco analogues Nucleosides, Nucleotides & Nucleic Acids. 10: 1525-1549. DOI: 10.1080/07328319108046680 |
0.365 |
|
| 1991 |
Aerschot AV, Balzarini J, Clercq ED, Herdewijn P. Synthesis and Antiviral Activity of 1.4-Dioxane, 1.4-Oxathiane and 1,4-Morpholine Nucleoside Analogues Nucleosides, Nucleotides & Nucleic Acids. 10: 591-592. DOI: 10.1080/07328319108046540 |
0.383 |
|
| 1991 |
Aerschot AV, Kerremans L, Balzarini J, Clercq ED, Herdewijn P. Synthesis and Anti-HIV Activity of Dideoxycytidine Analogues Containing a Pyranose Carbohydrate Moiety Nucleosides, Nucleotides & Nucleic Acids. 10: 589-590. DOI: 10.1080/07328319108046539 |
0.361 |
|
| 1991 |
Augustyns K, Van Aerschot A, Herdewijn P. Ugar Modified Oligonucleotides Nucleosides and Nucleotides. 10: 587-588. DOI: 10.1080/07328319108046538 |
0.382 |
|
| 1991 |
Wigerinck P, Van Aerschot A, De Clercq E, Herdewijn P. 5-(Thien-2-Yl)-Z‘-Deoxyuridine: A Nem And Potent Inhibitor Of Herpes Simplex Virus Type 1 Replication Nucleosides and Nucleotides. 10: 585-586. DOI: 10.1080/07328319108046537 |
0.354 |
|
| 1991 |
Wigerinck P, Aerschot AV, Kerremans L, Balzarini J, Clercq ED, Claes P, Herdewijn P. Synthesis of Thymidine Analogues with a Cyanoimido Substituent Nucleosides, Nucleotides & Nucleic Acids. 10: 583-584. DOI: 10.1080/07328319108046536 |
0.376 |
|
| 1991 |
Herdewijn P, Kerremans L, Wigerinck P, Vandendriessche F, Aerschot AV. Synthesis of thymidine from 5-iodo-2'-deoxyuridine Tetrahedron Letters. 32: 4397-4400. DOI: 10.1016/S0040-4039(00)92180-4 |
0.368 |
|
| 1991 |
Van Aeroschot A, Jie L, Herdewijn P. Synthesis of 5′-O-phosphonomethyl-2′,3′-didehydro-2′,3′-dideoxyuridine by use of P-methoxybenzyl as a N3-protecting group Tetrahedron Letters. 32: 1905-1908. DOI: 10.1016/S0040-4039(00)85994-8 |
0.337 |
|
| 1991 |
Herdewijn P, Ruf K, Pfleiderer W. Synthesis of modified oligomeric 2'-5'A analogues: Potential antiviral agents Helvetica Chimica Acta. 74: 7-23. DOI: 10.1002/Hlca.19910740104 |
0.508 |
|
| 1990 |
Wigerinck P, Aerschot AV, Janssen G, Claes P, Balzarini J, Clercq ED, Herdewijn P. Synthesis and antiviral activity of 3'-heterocyclic substituted 3'-deoxythymidines. Journal of Medicinal Chemistry. 33: 868-873. PMID 2299650 DOI: 10.1021/Jm00164A063 |
0.375 |
|
| 1990 |
Aerschot AV, Everaert D, Gosselin G, Peeters O, Blaton N, Ranter CD, Imbach J-, Balzarini J, Clercq ED, Herdewijn P. 2'-Azido-2',3'-dideoxythymidine: synthesis and crystal structure of a 2'-substituted dideoxynucleoside. Antiviral Research. 14: 357-369. PMID 2088211 DOI: 10.1016/0166-3542(90)90054-B |
0.384 |
|
| 1990 |
Jie L, Aerschot AV, Balzarini J, Janssen G, Busson R, Hoogmartens J, Clercq ED, Herdewijn P. 5'-O-phosphonomethyl-2',3'-dideoxynucleosides: synthesis and anti-HIV activity. Journal of Medicinal Chemistry. 33: 2481-2487. PMID 1697345 DOI: 10.1021/Jm00171A023 |
0.317 |
|
| 1990 |
Oivanen M, Viinamäki T, Zavgorodny S, Polianski M, Azhayev A, Aerschot AV, Herdewijn P, Lönnberg H. Hydrolytic stability of potential antiviral nucleoside analogues: 3'-substituted 2',3'-dideoxy- and 2',3'-didehydro-2',3'-dideoxyribonucleosides Collection of Czechoslovak Chemical Communications. 55: 17-20. DOI: 10.1135/Cccc1990S017 |
0.324 |
|
| 1990 |
Balzarini J, Aerschot AV, Herdewijn P, Clercq ED. Potent and Selective Anti‐HIV Activity of 5‐Chloro‐Substituted Derivatives of 3′‐Azido‐2′,3′‐Dideoxycytidine, 3′‐Fluoro‐2′,3′‐Dideoxycytidine, and 2′,3′‐Didehydro‐2′,3′‐Dideoxycytidine Annals of the New York Academy of Sciences. 616: 480-482. DOI: 10.1111/J.1749-6632.1990.Tb17870.X |
0.322 |
|
| 1989 |
Robins MJ, Wood SG, Dalley NK, Herdewijn P, Balzarini J, De Clercq E. Nucleic acid related compounds. 57. Synthesis, x-ray crystal structure, lipophilic partition properties, and antiretroviral activities of anomeric 3'-azido-2',3'-dideoxy-2,6-diaminopurine ribosides. Journal of Medicinal Chemistry. 32: 1763-8. PMID 2754702 DOI: 10.1021/Jm00128A017 |
0.316 |
|
| 1989 |
Aerschot AV, Herdewijn P, Balzarini J, Pauwels R, Clercq ED. 3'-Fluoro-2',3'-dideoxy-5-chlorouridine: most selective anti-HIV-1 agent among a series of new 2'- and 3'-fluorinated 2',3'-dideoxynucleoside analogues. Journal of Medicinal Chemistry. 32: 1743-1749. PMID 2754700 DOI: 10.1021/Jm00128A013 |
0.302 |
|
| 1989 |
Aerschot AV, Herdewijn P, Janssen G, Cools M, Clercq ED. Synthesis and antiviral activity evaluation of 3'-fluoro-3'-deoxyribonucleosides: broad-spectrum antiviral activity of 3'-fluoro-3'-deoxyadenosine. Antiviral Research. 12: 133-150. PMID 2624455 DOI: 10.1016/0166-3542(89)90047-8 |
0.394 |
|
| 1989 |
Balzarini J, Van Aerschot A, Herdewijn P, De Clercq E. 2′,3′-Didehydro-2′,3′-dideoxy-5-chlorocytidine is a selective anti-retrovirus agent Biochemical and Biophysical Research Communications. 164: 1190-1197. PMID 2590197 DOI: 10.1016/0006-291X(89)91795-6 |
0.344 |
|
| 1989 |
Balzarini J, Herdewijn P, De Clercq E. Potentiating effect of ribavirin on the anti-retrovirus activity of 3′-azido-2,6-diaminopurine-2′,3′-dideoxyriboside in vitro and in vivo Antiviral Research. 11: 161-171. PMID 2545163 DOI: 10.1016/0166-3542(89)90001-6 |
0.305 |
|
| 1989 |
Herdewijn P, Balzarini J, Pauwels R, Janssen G, Aerschot AV, Clercq ED. Synthesis and Biological Activity of the Mono- and Diamino Analogues of 2′-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine (A Structural Component of Agrocin 84) and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine Nucleosides, Nucleotides & Nucleic Acids. 8: 1231-1257. DOI: 10.1080/07328318908054329 |
0.355 |
|
| 1989 |
Aerschot AV, Balzarini J, Pauwels R, Wigerinck P, Clercq ED, Herdewijn P. Sugar and Base-Modified 2′,3′-Dideoxynucleosides as Potential Anti-Aids Drugs Nucleosides, Nucleotides & Nucleic Acids. 8: 1125-1126. DOI: 10.1080/07328318908054306 |
0.338 |
|
| 1989 |
Aerschot AV, Balzarini J, Clercq ED, Herdewijn P. Synthesis of 3’-Fluoro-3’-Deoxyribonucleosides: ANTI-HIV-1 And Cytostatic Properties Nucleosides and Nucleotides. 8: 1123-1124. DOI: 10.1080/07328318908054305 |
0.406 |
|
| 1989 |
Aerschot AV, Balzarini J, Pauwels R, Kerremans L, Clercq ED, Herdewijn P. Influence of Fluorination of the Sugar Moiety on the Anti-HIV-1 Activity of 2′,3′-Dideoxynucleosides Nucleosides, Nucleotides & Nucleic Acids. 8: 1121-1122. DOI: 10.1080/07328318908054304 |
0.336 |
|
| 1989 |
Herdewijn P, Aerschot AV. Some Examples Of The Use Of Trifluoromethane Sulfonic Anhydride In Nucleic Acid Chemistry Nucleosides and Nucleotides. 8: 933-937. DOI: 10.1080/07328318908054248 |
0.319 |
|
| 1989 |
Clercq ED, Aerschot AV, Herdewijn P, Baba M, Pauwels R, Balzarini J. Anti-Hiv-1 Activity of 2′,3′-Dideoxinucleoside Analogues : Structure-Activity Relationship Nucleosides, Nucleotides & Nucleic Acids. 8: 659-671. DOI: 10.1080/07328318908054206 |
0.345 |
|
| 1989 |
Herdewijn P, Aerschot AV, Kerremans L. Synthesis of Nucleosides Fluorinated in the Sugar Moiety. the Application of Diethylaminosulfur Trifluoride to the Synthesis of Fluorinated Nucleosides Nucleosides and Nucleotides. 8: 65-96. DOI: 10.1080/07328318908054159 |
0.308 |
|
| 1989 |
Herdewijn P, Van Aerschot A, Pfleiderer W. Synthesis of 2-Amino-6-acetamidomethyl-9-(β-D-ribofuranosyl) purine Synthesis. 1989: 961-962. DOI: 10.1055/S-1989-27448 |
0.503 |
|
| 1989 |
Herdewijn P, Van Aerschot A. Synthesis of 9-(3-azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-2,6-diaminopurine (AzddDAP) Tetrahedron Letters. 30: 855-858. DOI: 10.1016/S0040-4039(01)80635-3 |
0.364 |
|
| 1989 |
Herdewijn P. Reaction of adenine nucleosides, tosylated in the carbohydrate moiety, with lithium triethylborohydride Tetrahedron. 45: 6563-6580. DOI: 10.1016/S0040-4020(01)89533-8 |
0.31 |
|
| 1989 |
Herdewijn P, Charubala R, De Clercq E, Pfleiderer W. Nucleotides. Part. XXXII. Synthesis of 2?-5? Connected oligonucleotides. Prodrugs for antiviral and antitumoral nucleosides Helvetica Chimica Acta. 72: 1739-1748. DOI: 10.1002/Hlca.19890720811 |
0.526 |
|
| 1989 |
Herdewijn P, Charubala R, Pfleiderer W. Nucleotides. Part XXXI. Modified Oligomeric 2?-5? A Analogues: Synthesis of 2?-5? oligonucleotides with 9-(3?-azido-3?-deoxy-?-D-xylofuranosyl)adenine and 9-(3?-amino-3?-deoxy-?-D-xylofuranosyl)adenine as modified nucleosides Helvetica Chimica Acta. 72: 1729-1738. DOI: 10.1002/Hlca.19890720810 |
0.507 |
|
| 1988 |
Herdewijn P, Balzarini J, Baba M, Pauwels R, Aerschot AV, Janssen G, Clercq ED. Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides. Journal of Medicinal Chemistry. 31: 2040-2048. PMID 3172142 DOI: 10.1021/Jm00118A033 |
0.335 |
|
| 1988 |
Balzarini J, Baba M, Pauwels R, Herdewijn P, Clercq ED. Anti-retrovirus activity of 3′-fluoro- and 3′-azido-substituted pyrimidine 2′,3′-dideoxynucleoside analogues Biochemical Pharmacology. 37: 2847-2856. PMID 2840080 DOI: 10.1016/0006-2952(88)90049-4 |
0.337 |
|
| 1988 |
Balzarini J, Herdewijn P, Pauwels R, Broder S, Clercq ED. Alpha, beta- and beta, gamma-methylene 5'-phosphonate derivatives of 3'-azido-2',3'-dideoxythymidine-5'-triphosphate. Correlation between affinity for reverse transcriptase, susceptibility to hydrolysis by phosphodiesterases and anti-retrovirus activity. Biochemical Pharmacology. 37: 2395-2403. PMID 2455521 DOI: 10.1016/0006-2952(88)90366-8 |
0.304 |
|
| 1988 |
Aerschot AV, Herdewijn P, Vanderhaeghe H. Silica gel functionalised with different spacers as solid support for oligonucleotide synthesis Nucleosides and Nucleotides. 7: 75-90. DOI: 10.1080/07328318808068704 |
0.314 |
|
| 1987 |
Herdewijn P, Pauwels R, Baba M, Balzarini J, Clercq ED. Synthesis and anti-HIV activity of various 2'- and 3'-substituted 2',3'-dideoxyadenosines: a structure-activity analysis. Journal of Medicinal Chemistry. 30: 2131-2137. PMID 3499515 DOI: 10.1021/Jm00394A034 |
0.367 |
|
| 1987 |
Balzarini J, Robins MJ, Zou RM, Herdewijn P, De Clercq E. The 2',3'-dideoxyriboside of 2,6-diaminopurine and its 2',3'-didehydro derivative inhibit the deamination of 2',3'-dideoxyadenosine, an inhibitor of human immunodeficiency virus (HIV) replication. Biochemical and Biophysical Research Communications. 145: 277-83. PMID 3496090 DOI: 10.1016/0006-291X(87)91317-9 |
0.315 |
|
| 1987 |
Balzarini J, Pauwels R, Baba M, Robins MJ, Zou RM, Herdewijn P, De Clercq E. The 2',3'-dideoxyriboside of 2,6-diaminopurine selectively inhibits human immunodeficiency virus (HIV) replication in vitro. Biochemical and Biophysical Research Communications. 145: 269-76. PMID 3496089 DOI: 10.1016/0006-291X(87)91316-7 |
0.317 |
|
| 1987 |
Baba M, Pauwels R, Herdewijn P, Clercq ED, Desmyter J, Vandeputte M. Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro Biochemical and Biophysical Research Communications. 142: 128-134. PMID 3028398 DOI: 10.1016/0006-291X(87)90460-8 |
0.33 |
|
| 1987 |
Ruf K, Herdewijn P, Pfleiderer W. Synthesis of 2′-5′ Adenylate Trimers Containing 3′-Modified β-D-Xylofuranosyl-Adenine Derivatives at the 2′-End Nucleosides and Nucleotides. 6: 527-528. DOI: 10.1080/07328318708056277 |
0.529 |
|
| 1987 |
Herdewijn P, Charubala R, Pauwels R, Pfleiderer P, Clercq E. Synthesis and biological activity of 3'modified 2'5'adenylate trimers Nucleosides and Nucleotides. 6: 443-444. DOI: 10.1080/07328318708056251 |
0.387 |
|
| 1987 |
Herdewijn P, Charubala R, Pauwels R, Pfleiderer W, De Clercq E. Synthesis and activity of oligonucleotides containing a biologically active nucleoside at the 2end Nucleosides and Nucleotides. 6: 441-442. DOI: 10.1080/07328318708056250 |
0.482 |
|
| 1986 |
Herdewijn P, Claes PJ, Vanderhaeghe H. Synthesis of Δ3-1-methylene-1-carbacephems Journal of Medicinal Chemistry. 29: 661-664. PMID 3701783 DOI: 10.1021/Jm00155A013 |
0.355 |
|
| 1986 |
Balzarini J, Pauwels R, Herdewijn P, Clercq ED, Cooney DA, Kang G, Dalal M, Johns DG, Broder S. Potent and selective anti-HTLV-III/LAV activity of 2',3'-dideoxycytidinene, the 2',3'-unsaturated derivative of 2',3'-dideoxycytidine. Biochemical and Biophysical Research Communications. 140: 735-742. PMID 3022729 DOI: 10.1016/0006-291X(86)90793-X |
0.346 |
|
| 1986 |
Herdewijn P, Claes PJ, Vanderhaeghe H. Synthesis of Δ3-1-Methylene-1-carbacephems. Cheminform. 17. DOI: 10.1002/Chin.198638336 |
0.349 |
|
| 1985 |
Bernaerts R, Clercq Ed, Balzarini J, Herdewijn P, Verbruggen A. Incorporation of carbocyclic (E)-5-(2-iodovinyl)-2′-deoxyuridine (C-IBDU) into DNA of herpes simplex virus-infected cells Antiviral Research. 5: 51-56. PMID 3002266 DOI: 10.1016/S0166-3542(85)80008-5 |
0.315 |
|
| 1985 |
Herdewijn P, De Clercq E, Balzarini J, Vanderhaeghe H. Synthesis and antiviral activity of the carbocyclic analogues of (E)-5-(2-halovinyl)-2′-deoxyuridines and (E)-5-(2-halovinyl)-2′-deoxycytidines Journal of Medicinal Chemistry. 28: 550-555. PMID 2985782 DOI: 10.1021/Jm50001A003 |
0.311 |
|
| 1985 |
Clercq ED, Balzarini J, Bernaerts R, Herdewijn P, Verbruggen A. Selective antiherpetic activity of carbocyclic analogues of (E)-5-(2-halogenovinyl)-2'-deoxyuridines: dependence on specific phosphorylation by viral thymidine kinase. Biochemical and Biophysical Research Communications. 126: 397-403. PMID 2982373 DOI: 10.1016/0006-291X(85)90619-9 |
0.313 |
|
| 1985 |
Colla L, Herdewijn P, De Clercq E. Synthesis and biological activity of 3'-azido- and 3'-amino substituted nucleoside analogs European Journal of Medicinal Chemistry. 20: 295-301. DOI: 10.1002/Chin.198552311 |
0.363 |
|
| 1983 |
Herdewijn P, Claes PJ, Vanderhaeghe H. Synthesis Of Trans(.+-.)6-Phenoxyacetamido-1-Methylene-3,3-Dicarbomethoxy-1-Carbapenam Cheminform. 14. DOI: 10.1002/Chin.198311314 |
0.345 |
|
| 1982 |
Herdewijn P, Claes PJ, Vanderhaeghe H. Synthesis of trans(±)6-phenoxyacetamido-1-methylene-3,3-dicarboxymethyl-1-carbapenam Canadian Journal of Chemistry. 60: 2903-2907. DOI: 10.1139/V82-416 |
0.341 |
|
| Show low-probability matches. |