Robert D. Phair - Publications

Integrative Bioinformatics Inc 
molecular cell biology, metabolism, physiology, non-steady state tracer kinetics, ProcessDB

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Jacome-Sosa M, Hu Q, Manrique-Acevedo CM, Phair RD, Parks EJ. Human intestinal lipid storage through sequential meals reveals faster dinner appearance is associated with hyperlipidemia. Jci Insight. 6. PMID 34369385 DOI: 10.1172/jci.insight.148378  1
2019 Kashi AA, Davis RW, Phair RD. The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS. Diagnostics (Basel, Switzerland). 9. PMID 31357483 DOI: 10.3390/diagnostics9030082  0.01
2018 Lippincott-Schwartz J, Snapp EL, Phair RD. The Development and Enhancement of FRAP as a Key Tool for Investigating Protein Dynamics. Biophysical Journal. PMID 30219286 DOI: 10.1016/J.Bpj.2018.08.007  1
2018 Phair RD. Differential equation methods for simulation of GFP kinetics in non-steady state experiments. Molecular Biology of the Cell. PMID 29367436 DOI: 10.1091/mbc.E17-06-0396  0.01
2017 Kieffer-Kwon KR, Nimura K, Rao SSP, Xu J, Jung S, Pekowska A, Dose M, Stevens E, Mathe E, Dong P, Huang SC, Ricci MA, Baranello L, Zheng Y, Ardori FT, ... ... Phair RD, et al. Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation. Molecular Cell. PMID 28803781 DOI: 10.1016/J.Molcel.2017.07.013  1
2015 McLaren DG, Previs SF, Phair RD, Stout SJ, Xie D, Chen Y, Salituro GM, Xu SS, Castro-Perez JM, Opiteck GJ, Akinsanya KO, Cleary MA, Dansky HM, Johns DG, Roddy TP. Evaluation of Cholesteryl Ester Transfer Protein Activity in vivo Under Non-Steady State Conditions: Influence of anacetrapib on High Density Lipoprotein Triglyceride Flux. Journal of Lipid Research. PMID 26658238 DOI: 10.1194/Jlr.M063842  1
2015 Phair RD. Kinetic Modeling and the Rise of Systems Pharmacology. Journal of Lipid Research. PMID 26590172 DOI: 10.1194/Jlr.C065482  1
2014 Phair RD. Mechanistic modeling confronts the complexity of molecular cell biology. Molecular Biology of the Cell. 25: 3494-6. PMID 25368428 DOI: 10.1091/mbc.E14-08-1333  1
2013 Nakahashi H, Kwon KR, Resch W, Vian L, Dose M, Stavreva D, Hakim O, Pruett N, Nelson S, Yamane A, Qian J, Dubois W, Welsh S, Phair RD, Pugh BF, et al. A genome-wide map of CTCF multivalency redefines the CTCF code. Cell Reports. 3: 1678-89. PMID 23707059 DOI: 10.1016/J.Celrep.2013.04.024  1
2012 Ramos-Roman MA, Lapidot SA, Phair RD, Parks EJ. Insulin activation of plasma nonesterified fatty acid uptake in metabolic syndrome. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1799-808. PMID 22723441 DOI: 10.1161/Atvbaha.112.250019  1
2012 Phair RD. Why and how to expand the role of systems biology in pharmaceutical research and development. Advances in Experimental Medicine and Biology. 736: 533-42. PMID 22161350 DOI: 10.1007/978-1-4419-7210-1_31  1
2010 Lippincott-Schwartz J, Phair RD. Lipids and cholesterol as regulators of traffic in the endomembrane system. Annual Review of Biophysics. 39: 559-78. PMID 20192772 DOI: 10.1146/Annurev.Biophys.093008.131357  1
2009 Melnick M, Phair RD, Lapidot SA, Jaskoll T. Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. Bmc Developmental Biology. 9: 32. PMID 19500387 DOI: 10.1186/1471-213X-9-32  1
2008 Patterson GH, Hirschberg K, Polishchuk RS, Gerlich D, Phair RD, Lippincott-Schwartz J. Transport through the Golgi apparatus by rapid partitioning within a two-phase membrane system. Cell. 133: 1055-67. PMID 18555781 DOI: 10.1016/J.Cell.2008.04.044  1
2007 Darzacq X, Shav-Tal Y, de Turris V, Brody Y, Shenoy SM, Phair RD, Singer RH. In vivo dynamics of RNA polymerase II transcription. Nature Structural & Molecular Biology. 14: 796-806. PMID 17676063 DOI: 10.1038/Nsmb1280  1
2007 Kruhlak M, Crouch EE, Orlov M, Montaño C, Gorski SA, Nussenzweig A, Misteli T, Phair RD, Casellas R. The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks. Nature. 447: 730-4. PMID 17554310 DOI: 10.1038/Nature05842  1
2005 Liu W, Duden R, Phair RD, Lippincott-Schwartz J. ArfGAP1 dynamics and its role in COPI coat assembly on Golgi membranes of living cells. The Journal of Cell Biology. 168: 1053-63. PMID 15795316 DOI: 10.1083/Jcb.200410142  1
2004 Lin Y, Dueker SR, Follett JR, Fadel JG, Arjomand A, Schneider PD, Miller JW, Green R, Buchholz BA, Vogel JS, Phair RD, Clifford AJ. Quantitation of in vivo human folate metabolism. The American Journal of Clinical Nutrition. 80: 680-91. PMID 15321809 DOI: 10.1093/Ajcn/80.3.680  1
2004 Phair RD, Scaffidi P, Elbi C, Vecerová J, Dey A, Ozato K, Brown DT, Hager G, Bustin M, Misteli T. Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Molecular and Cellular Biology. 24: 6393-402. PMID 15226439 DOI: 10.1128/Mcb.24.14.6393-6402.2004  1
2004 Phair RD, Gorski SA, Misteli T. Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy. Methods in Enzymology. 375: 393-414. PMID 14870680 DOI: 10.1016/S0076-6879(03)75025-3  1
2003 Altan-Bonnet N, Phair RD, Polishchuk RS, Weigert R, Lippincott-Schwartz J. A role for Arf1 in mitotic Golgi disassembly, chromosome segregation, and cytokinesis. Proceedings of the National Academy of Sciences of the United States of America. 100: 13314-9. PMID 14585930 DOI: 10.1073/Pnas.2234055100  1
2002 Dundr M, Hoffmann-Rohrer U, Hu Q, Grummt I, Rothblum LI, Phair RD, Misteli T. A kinetic framework for a mammalian RNA polymerase in vivo. Science (New York, N.Y.). 298: 1623-6. PMID 12446911 DOI: 10.1126/Science.1076164  1
2002 Biesele J, Foster D, Jacquez GM, Phair RD, Simon C. John A. Jacquez. Mathematical Biosciences. 180: vii-ix. PMID 12387932 DOI: 10.1016/S0025-5564(02)00159-1  1
2002 Presley JF, Ward TH, Pfeifer AC, Siggia ED, Phair RD, Lippincott-Schwartz J. Dissection of COPI and Arf1 dynamics in vivo and role in Golgi membrane transport. Nature. 417: 187-93. PMID 12000962 DOI: 10.1038/417187A  1
2001 Phair RD, Misteli T. Kinetic modelling approaches to in vivo imaging. Nature Reviews. Molecular Cell Biology. 2: 898-907. PMID 11733769 DOI: 10.1038/35103000  1
2001 Nichols BJ, Kenworthy AK, Polishchuk RS, Lodge R, Roberts TH, Hirschberg K, Phair RD, Lippincott-Schwartz J. Rapid cycling of lipid raft markers between the cell surface and Golgi complex. The Journal of Cell Biology. 153: 529-41. PMID 11331304 DOI: 10.1083/Jcb.153.3.529  1
2000 Hirschberg K, Phair RD, Lippincott-Schwartz J. Kinetic analysis of intracellular trafficking in single living cells with vesicular stomatitis virus protein G-green fluorescent protein hybrids. Methods in Enzymology. 327: 69-89. PMID 11044975 DOI: 10.1016/S0076-6879(00)27268-6  1
2000 Phair RD, Misteli T. High mobility of proteins in the mammalian cell nucleus. Nature. 404: 604-9. PMID 10766243 DOI: 10.1038/35007077  1
1999 Zaal KJ, Smith CL, Polishchuk RS, Altan N, Cole NB, Ellenberg J, Hirschberg K, Presley JF, Roberts TH, Siggia E, Phair RD, Lippincott-Schwartz J. Golgi membranes are absorbed into and reemerge from the ER during mitosis. Cell. 99: 589-601. PMID 10612395 DOI: 10.1016/S0092-8674(00)81548-2  1
1998 Hirschberg K, Miller CM, Ellenberg J, Presley JF, Siggia ED, Phair RD, Lippincott-Schwartz J. Kinetic analysis of secretory protein traffic and characterization of golgi to plasma membrane transport intermediates in living cells. The Journal of Cell Biology. 143: 1485-503. PMID 9852146 DOI: 10.1083/Jcb.143.6.1485  1
1997 Shamburek RD, Pentchev PG, Zech LA, Blanchette-Mackie J, Carstea ED, VandenBroek JM, Cooper PS, Neufeld EB, Phair RD, Brewer HB, Brady RO, Schwartz CC. Intracellular trafficking of the free cholesterol derived from LDL cholesteryl ester is defective in vivo in Niemann-Pick C disease: insights on normal metabolism of HDL and LDL gained from the NP-C mutation. Journal of Lipid Research. 38: 2422-35. PMID 9458266  1
1997 Phair RD. Development of kinetic models in the nonlinear world of molecular cell biology. Metabolism: Clinical and Experimental. 46: 1489-95. PMID 9439549 DOI: 10.1016/S0026-0495(97)90154-2  1
1996 Fayazi AH, Lapidot SA, Huang BK, Tucker RW, Phair RD. Resolution of the basal plasma membrane calcium flux in vascular smooth muscle cells. The American Journal of Physiology. 270: H1972-8. PMID 8764246 DOI: 10.1152/Ajpheart.1996.270.6.H1972  1
1996 Lapidot SA, Huang BK, Fayazi A, Russek LN, Strickberger SA, Brooks AE, Phair RD. Mechanisms for Ca signaling in vascular smooth muscle: resolved from 45Ca uptake and efflux experiments. Cell Calcium. 19: 167-84. PMID 8689674 DOI: 10.1016/S0143-4160(96)90085-8  1
1995 Lapidot SA, Phair RD. Platelet-derived growth factor causes sustained depletion of both inositol trisphosphate-sensitive and caffeine-sensitive intracellular calcium stores in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 44-51. PMID 7749815 DOI: 10.1161/01.Atv.15.1.44  1
1991 Georgopoulos A, Phair RD. Abnormal clearance of postprandial Sf 100-400 plasma lipoproteins in insulin-dependent diabetes mellitus. Journal of Lipid Research. 32: 1133-41. PMID 1940637  1
1989 Hai CM, Phair RD. Forskolin and caffeine induce Ca2+ release from intracellular stores in rabbit aorta. The American Journal of Physiology. 257: C413-8. PMID 2782384 DOI: 10.1152/Ajpcell.1989.257.3.C413  1
1988 Strickberger SA, Russek LN, Phair RD. Evidence for increased aortic plasma membrane calcium transport caused by experimental atherosclerosis in rabbits. Circulation Research. 62: 75-80. PMID 3335059 DOI: 10.1161/01.Res.62.1.75  1
1988 Phair RD. Cellular calcium and atherosclerosis: a brief review. Cell Calcium. 9: 275-84. PMID 3066492 DOI: 10.1016/0143-4160(88)90008-5  1
1986 Venkatesh N, Somani P, Bersohn M, Phair R, Kato R, Singh BN. Electropharmacology of amiodarone: absence of relationship to serum, myocardial, and cardiac sarcolemmal membrane drug concentrations. American Heart Journal. 112: 916-22. PMID 3776818 DOI: 10.1016/0002-8703(86)90300-5  1
1986 Hai CM, Phair RD. Kinetic identification of an intracellular calcium compartment sensitive to phosphate and dinitrophenol in intact isolated rabbit aorta. Circulation Research. 59: 85-92. PMID 2426005 DOI: 10.1161/01.Res.59.1.85  1
1986 Phair RD, Hai CM. Resolution of intracellular calcium metabolism in intact segments of rabbit aorta. Circulation Research. 59: 74-84. PMID 2426004 DOI: 10.1161/01.Res.59.1.74  1
1985 Gonen B, Patsch W, Kuisk I, Goldberg A, Phair R, Schonfeld G. Altered HDL subclasses in endogenous hypertriglyceridemia are not affected by weight reduction Metabolism. 34: 494-501. PMID 3990564 DOI: 10.1016/0026-0495(85)90217-3  1
1984 Phair RD, Pek SB, Lands WE. Arachidonic acid induced release of insulin and glucagon: role of endogenous prostaglandins in pancreatic hormone secretion. DiabèTe & MéTabolisme. 10: 71-7. PMID 6430728  1
1984 Dempsher DP, Gann DS, Phair RD. A mechanistic model of ACTH-stimulated cortisol secretion. The American Journal of Physiology. 246: R587-96. PMID 6326602  1
1984 Hai CM, Phair RD. Release of different aortic calcium stores by forskolin and caffeine Federation Proceedings. 43: no. 832.  1
1979 Phair RD, Sparks HV. Adenosine content of skeletal muscle during active hyperemia and ischemic contraction. The American Journal of Physiology. 237: H1-9. PMID 464063  1
1979 Belloni FL, Phair RD, Sparks HV. The role of adenosine in prolonged vasodilation following flow-restricted exercise of canine skeletal muscle. Circulation Research. 44: 759-66. PMID 428070 DOI: 10.1161/01.Res.44.6.759  1
1979 Phair RD, Rago NS, Lands WEM, Pek S. Role of endogenous prostaglandins (PGs) in insulin and glucagon responses to fatty acids (FAs) Federation Proceedings. 38: no. 3419.  1
1978 Berman M, Hall M, Levy RI, Eisenberg S, Bilheimer DW, Phair RD, Goebel RH. Metabolsim of apoB and apoC lipoproteins in man: kinetic studies in normal and hyperlipoproteininemic subjects. Journal of Lipid Research. 19: 38-56. PMID 202659  0.48
1975 Eckman WW, Phair RD, Fenstermacher JD, Patlak CS, Kennedy C, Sokoloff L. Permeability limitation in estimation of local brain blood flow with [14C]antipyrine. The American Journal of Physiology. 229: 215-21. PMID 1096644 DOI: 10.1152/Ajplegacy.1975.229.1.215  1
1975 Phair RD, Hammond MG, Bowden JA, Fried M, Fisher WR, Berman M. Preliminary model for human lipoprotein metabolism in hyperlipoproteinemia. Federation Proceedings. 34: 2263-70. PMID 172373  1
1973 Eckman WW, Phair RD, Fenstermacher JD, Sokoloff L. Measurement of regional blood brain barrier permeability to 14C antipyrine in normal cats Federation Proceedings. 32: I.  1
1971 Degroot LJ, Decostre P, Phair R. A mathematical model of human iodine metabolism Journal of Clinical Endocrinology and Metabolism. 32: 757-765. PMID 4102730 DOI: 10.1210/Jcem-32-6-757  1
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