Year |
Citation |
Score |
2023 |
Johnson CW, Fetics SK, Davis KP, Rodrigues JA, Mattos C. Allosteric site variants affect GTP hydrolysis on Ras. Protein Science : a Publication of the Protein Society. e4767. PMID 37615343 DOI: 10.1002/pro.4767 |
0.819 |
|
2022 |
Volmar AY, Guterres H, Zhou H, Reid D, Pavlopoulos S, Makowski L, Mattos C. Mechanisms of isoform-specific residue influence on GTP-bound HRas, KRas and NRas. Biophysical Journal. PMID 35794829 DOI: 10.1016/j.bpj.2022.07.005 |
0.801 |
|
2022 |
Li ZL, Mattos C, Buck M. Computational studies of the principle of dynamic-change-driven protein interactions. Structure (London, England : 1993). PMID 35381186 DOI: 10.1016/j.str.2022.03.008 |
0.349 |
|
2022 |
Johnson CW, Seo HS, Terrell EM, Yang MH, KleinJan F, Gebregiworgis T, Gasmi-Seabrook GMC, Geffken EA, Lakhani J, Song K, Bashyal P, Popow O, Paulo JA, Liu A, Mattos C, et al. Regulation of GTPase function by autophosphorylation. Molecular Cell. PMID 35202574 DOI: 10.1016/j.molcel.2022.02.011 |
0.396 |
|
2021 |
Cookis T, Mattos C. Crystal Structure Reveals the Full Ras-Raf Interface and Advances Mechanistic Understanding of Raf Activation. Biomolecules. 11. PMID 34356620 DOI: 10.3390/biom11070996 |
0.424 |
|
2021 |
Packer MR, Parker JA, Chung JK, Li Z, Lee YK, Cookis T, Guterres H, Alvarez S, Hossain MA, Donnelly DP, Agar JN, Makowski L, Buck M, Groves JT, Mattos C. Raf promotes dimerization of the Ras G-domain with increased allosteric connections. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33653954 DOI: 10.1073/pnas.2015648118 |
0.401 |
|
2020 |
Agarwal S, Smith M, De La Rosa I, Verba KA, Swartz P, Segura-Totten M, Mattos C. Development of a structure-analysis pipeline using multiple-solvent crystal structures of barrier-to-autointegration factor. Acta Crystallographica. Section D, Structural Biology. 76: 1001-1014. PMID 33021502 DOI: 10.1107/S2059798320011341 |
0.372 |
|
2020 |
Ojeda M, Johnson C, Mattos C. Determining conformational dynamics of the allosteric site in HRas R97G The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04065 |
0.349 |
|
2020 |
Packer MR, Parker JA, Chung JK, Li Z, Lee YK, Guterres H, Cookis T, Hossain A, Donnelly DP, Agar JN, Makowski L, Buck M, Groves JT, Mattos C. Raf promotes dimerization of the Ras G‐domain The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03461 |
0.426 |
|
2020 |
Volmar AY, Guterres H, Zhou H, Mattos C, Makowski L. Ras Structure, Dynamics and Conformational States Assessed by MD Simulations and Solution Wide angle X‐ray Scattering The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03160 |
0.785 |
|
2020 |
Schwabe M, Holzapfel G, Mattos C. Exploring the Rap1A Active Site Through Accelerated Molecular Dynamic Simulations The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02775 |
0.564 |
|
2020 |
Cookis T, Volmar A, Merritt K, Mattos C. Interaction between Ras and the two Ras‐Binding Domains of Raf kinase The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02405 |
0.774 |
|
2019 |
Jang H, Banerjee A, Marcus K, Makowski L, Mattos C, Gaponenko V, Nussinov R. The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin. Structure (London, England : 1993). PMID 31495533 DOI: 10.1016/J.Str.2019.08.009 |
0.339 |
|
2019 |
Marcus K, Mattos C. Water in Ras Superfamily Evolution. Journal of Computational Chemistry. PMID 31483874 DOI: 10.1002/Jcc.26060 |
0.443 |
|
2019 |
Johnson CW, Lin YJ, Reid D, Parker J, Pavlopoulos S, Dischinger P, Graveel C, Aguirre AJ, Steensma M, Haigis KM, Mattos C. Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Reports. 28: 1538-1550.e7. PMID 31390567 DOI: 10.1016/J.Celrep.2019.07.026 |
0.464 |
|
2019 |
Kearney BM, Schwabe M, Marcus K, Roberts DM, Dechene M, Swartz P, Mattos C. DRoP: Automated detection of conserved solvent binding sites on proteins. Proteins. PMID 31294888 DOI: 10.1002/Prot.25781 |
0.751 |
|
2019 |
Knihtila R, Volmar AY, Meilleur F, Mattos C. Titration of ionizable groups in proteins using multiple neutron data sets from a single crystal: application to the small GTPase Ras. Acta Crystallographica. Section F, Structural Biology Communications. 75: 111-115. PMID 30713162 DOI: 10.1107/S2053230X18018125 |
0.801 |
|
2018 |
Ashkar R, Bilheux HZ, Bordallo H, Briber R, Callaway DJE, Cheng X, Chu XQ, Curtis JE, Dadmun M, Fenimore P, Fushman D, Gabel F, Gupta K, Herberle F, Heinrich F, ... ... Mattos C, et al. Neutron scattering in the biological sciences: progress and prospects. Acta Crystallographica. Section D, Structural Biology. 74: 1129-1168. PMID 30605130 DOI: 10.1107/S2059798318017503 |
0.642 |
|
2018 |
Zhou H, Guterres H, Mattos C, Makowski L. Predicting X-ray solution scattering from flexible macromolecules. Protein Science : a Publication of the Protein Society. PMID 30230663 DOI: 10.1002/Pro.3508 |
0.401 |
|
2018 |
Parker JA, Volmar AY, Pavlopoulos S, Mattos C. K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D. Structure (London, England : 1993). PMID 29706533 DOI: 10.1016/J.Str.2018.03.018 |
0.787 |
|
2017 |
Parker JA, Mattos C. The K-Ras, N-Ras, and H-Ras Isoforms: Unique Conformational Preferences and Implications for Targeting Oncogenic Mutants. Cold Spring Harbor Perspectives in Medicine. PMID 29038336 DOI: 10.1101/Cshperspect.A031427 |
0.468 |
|
2017 |
Kauke MJ, Traxlmayr MW, Parker JA, Kiefer JD, Knihtila R, McGee J, Verdine G, Mattos C, Wittrup KD. An engineered protein antagonist of K-Ras/B-Raf interaction. Scientific Reports. 7: 5831. PMID 28724936 DOI: 10.1038/S41598-017-05889-7 |
0.483 |
|
2017 |
Johnson CW, Reid D, Parker JA, Salter S, Knihtila R, Kuzmic P, Mattos C. The small GTPases K-Ras, N-Ras and H-Ras have distinct biochemical properties determined by allosteric effects. The Journal of Biological Chemistry. PMID 28630043 DOI: 10.1074/Jbc.M117.778886 |
0.49 |
|
2017 |
Zhou H, Guterres H, Mattos C, Makowski L. Verifying Self-Consistency of Protein Structure and Dynamics through MD Simulation and WAXS Biophysical Journal. 112: 176a. DOI: 10.1016/J.Bpj.2016.11.972 |
0.418 |
|
2016 |
Johnson CW, Buhrman G, Ting PY, Colicelli J, Mattos C. Expression, purification, crystallization and X-ray data collection for RAS and its mutants. Data in Brief. 6: 423-7. PMID 26866052 DOI: 10.1016/J.Dib.2015.12.007 |
0.504 |
|
2015 |
Knihtila R, Holzapfel G, Weiss K, Meilleur F, Mattos C. Neutron Crystal Structure of RAS GTPase puts in question the Protonation State of the GTP γ-Phosphate. The Journal of Biological Chemistry. PMID 26515069 DOI: 10.1074/Jbc.M115.679860 |
0.698 |
|
2015 |
Mattos C. Ras: structural details to guide direct targeting. Aging. 7: 344-5. PMID 26080945 |
0.328 |
|
2015 |
Ting PY, Johnson CW, Fang C, Cao X, Graeber TG, Mattos C, Colicelli J. Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25999467 DOI: 10.1096/Fj.15-271510 |
0.494 |
|
2015 |
Marcus K, Mattos C. Direct Attack on RAS: Intramolecular Communication and Mutation-Specific Effects. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1810-8. PMID 25878362 DOI: 10.1158/1078-0432.Ccr-14-2148 |
0.5 |
|
2015 |
Fetics SK, Guterres H, Kearney BM, Buhrman G, Ma B, Nussinov R, Mattos C. Allosteric effects of the oncogenic RasQ61L mutant on Raf-RBD. Structure (London, England : 1993). 23: 505-16. PMID 25684575 DOI: 10.1016/J.Str.2014.12.017 |
0.788 |
|
2015 |
Parker JA, Mattos C. The Ras-Membrane Interface: Isoform-specific Differences in The Catalytic Domain. Molecular Cancer Research : McR. 13: 595-603. PMID 25566993 DOI: 10.1158/1541-7786.Mcr-14-0535 |
0.495 |
|
2014 |
Kearney BM, Johnson CW, Roberts DM, Swartz P, Mattos C. DRoP: a water analysis program identifies Ras-GTP-specific pathway of communication between membrane-interacting regions and the active site. Journal of Molecular Biology. 426: 611-29. PMID 24189050 DOI: 10.1016/J.Jmb.2013.10.036 |
0.824 |
|
2013 |
Johnson CW, Mattos C. The allosteric switch and conformational states in Ras GTPase affected by small molecules. The Enzymes. 33: 41-67. PMID 25033800 DOI: 10.1016/B978-0-12-416749-0.00003-8 |
0.473 |
|
2013 |
Nussinov R, Tsai CJ, Mattos C. 'Pathway drug cocktail': targeting Ras signaling based on structural pathways. Trends in Molecular Medicine. 19: 695-704. PMID 23953481 DOI: 10.1016/J.Molmed.2013.07.009 |
0.397 |
|
2012 |
Holzapfel G, Buhrman G, Mattos C. Shift in the equilibrium between on and off states of the allosteric switch in Ras-GppNHp affected by small molecules and bulk solvent composition. Biochemistry. 51: 6114-26. PMID 22845804 DOI: 10.1021/Bi300509J |
0.681 |
|
2012 |
Walters J, Schipper JL, Swartz P, Mattos C, Clark AC. Allosteric modulation of caspase 3 through mutagenesis. Bioscience Reports. 32: 401-11. PMID 22607239 DOI: 10.1042/Bsr20120037 |
0.415 |
|
2012 |
Prior IA, Lewis PD, Mattos C. A comprehensive survey of Ras mutations in cancer. Cancer Research. 72: 2457-67. PMID 22589270 DOI: 10.1158/0008-5472.Can-11-2612 |
0.406 |
|
2012 |
Gagnon KT, Biswas S, Zhang X, Brown BA, Wollenzien P, Mattos C, Maxwell ES. Structurally conserved Nop56/58 N-terminal domain facilitates archaeal box C/D ribonucleoprotein-guided methyltransferase activity. The Journal of Biological Chemistry. 287: 19418-28. PMID 22496443 DOI: 10.1074/Jbc.M111.323253 |
0.392 |
|
2011 |
Buhrman G, O'Connor C, Zerbe B, Kearney BM, Napoleon R, Kovrigina EA, Vajda S, Kozakov D, Kovrigin EL, Mattos C. Analysis of binding site hot spots on the surface of Ras GTPase. Journal of Molecular Biology. 413: 773-89. PMID 21945529 DOI: 10.1016/J.Jmb.2011.09.011 |
0.821 |
|
2011 |
Biswas S, Buhrman G, Gagnon K, Mattos C, Brown BA, Maxwell ES. Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features. Biochemistry. 50: 2907-18. PMID 21366326 DOI: 10.1021/Bi1020474 |
0.379 |
|
2011 |
Walters J, Swartz P, Mattos C, Clark AC. Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3. Archives of Biochemistry and Biophysics. 508: 31-8. PMID 21266160 DOI: 10.1016/J.Abb.2011.01.011 |
0.362 |
|
2011 |
Buhrman G, Kumar VS, Cirit M, Haugh JM, Mattos C. Allosteric modulation of Ras-GTP is linked to signal transduction through RAF kinase. The Journal of Biological Chemistry. 286: 3323-31. PMID 21098031 DOI: 10.1074/Jbc.M110.193854 |
0.47 |
|
2010 |
Buhrman G, Holzapfel G, Fetics S, Mattos C. Allosteric modulation of Ras positions Q61 for a direct role in catalysis. Proceedings of the National Academy of Sciences of the United States of America. 107: 4931-6. PMID 20194776 DOI: 10.1073/Pnas.0912226107 |
0.818 |
|
2009 |
Walters J, Pop C, Scott FL, Drag M, Swartz P, Mattos C, Salvesen GS, Clark AC. A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis. The Biochemical Journal. 424: 335-45. PMID 19788411 DOI: 10.1042/Bj20090825 |
0.329 |
|
2009 |
Dechene M, Wink G, Smith M, Swartz P, Mattos C. Multiple solvent crystal structures of ribonuclease A: an assessment of the method. Proteins. 76: 861-81. PMID 19291738 DOI: 10.1002/Prot.22393 |
0.78 |
|
2009 |
Brenke R, Kozakov D, Chuang GY, Beglov D, Hall D, Landon MR, Mattos C, Vajda S. Fragment-based identification of druggable 'hot spots' of proteins using Fourier domain correlation techniques. Bioinformatics (Oxford, England). 25: 621-7. PMID 19176554 DOI: 10.1093/Bioinformatics/Btp036 |
0.365 |
|
2008 |
Mattos C, Clark AC. Minimizing frustration by folding in an aqueous environment. Archives of Biochemistry and Biophysics. 469: 118-31. PMID 17719000 DOI: 10.1016/J.Abb.2007.07.007 |
0.326 |
|
2007 |
Buhrman G, Wink G, Mattos C. Transformation efficiency of RasQ61 mutants linked to structural features of the switch regions in the presence of Raf. Structure (London, England : 1993). 15: 1618-29. PMID 18073111 DOI: 10.1016/J.Str.2007.10.011 |
0.453 |
|
2007 |
Milam SL, Nicely NI, Feeney B, Mattos C, Clark AC. Rapid folding and unfolding of Apaf-1 CARD. Journal of Molecular Biology. 369: 290-304. PMID 17408690 DOI: 10.1016/J.Jmb.2007.02.105 |
0.697 |
|
2007 |
Buhrman G, Wink G, Mattos C. The structures of Q61 Ras mutants solved in a new space group reveals insights into the mechanism of intrinsic GTPase actitvity The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A640-C |
0.4 |
|
2007 |
Holzapfel GA, Miller CM, Mattos C. The crystal structures of Rap1a bound to GTP and GppNHp The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A640 |
0.659 |
|
2007 |
Subbiah SKV, Moe J, Desai D, Holzapfel GA, Wink G, Swartz P, Mattos C. Multiple Solvent Crystal Structures of Chymotrypsin: Comparision with Elastase The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A639 |
0.625 |
|
2007 |
De la Rosa I, Segura‐Totten M, Mattos C. Barrier‐to‐autointegration Factor (BAF): purification, crystallization and multiple solvent crystal structure The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A638-E |
0.389 |
|
2006 |
Feeney B, Pop C, Swartz P, Mattos C, Clark AC. Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3. Biochemistry. 45: 13249-63. PMID 17073446 DOI: 10.1021/Bi0611964 |
0.375 |
|
2006 |
Mattos C, Bellamacina CR, Peisach E, Pereira A, Vitkup D, Petsko GA, Ringe D. Multiple solvent crystal structures: probing binding sites, plasticity and hydration. Journal of Molecular Biology. 357: 1471-82. PMID 16488429 DOI: 10.1016/J.Jmb.2006.01.039 |
0.771 |
|
2005 |
Buhrman G, Parker B, Sohn J, Rudolph J, Mattos C. Structural mechanism of oxidative regulation of the phosphatase Cdc25B via an intramolecular disulfide bond. Biochemistry. 44: 5307-16. PMID 15807524 DOI: 10.1021/Bi047449F |
0.373 |
|
2004 |
Nicely NI, Kosak J, de Serrano V, Mattos C. Crystal structures of Ral-GppNHp and Ral-GDP reveal two binding sites that are also present in Ras and Rap. Structure (London, England : 1993). 12: 2025-36. PMID 15530367 DOI: 10.1016/J.Str.2004.08.011 |
0.779 |
|
2004 |
Mattos C, Cohen JD, Green DF, Tidor B, Karplus M. X-ray structural and simulation analysis of a protein mutant: the value of a combined approach. Proteins. 55: 733-42. PMID 15103635 DOI: 10.1002/Prot.20031 |
0.71 |
|
2003 |
Buhrman G, de Serrano V, Mattos C. Organic solvents order the dynamic switch II in Ras crystals. Structure (London, England : 1993). 11: 747-51. PMID 12842038 DOI: 10.1016/S0969-2126(03)00128-X |
0.505 |
|
2002 |
Mattos C. Protein-water interactions in a dynamic world. Trends in Biochemical Sciences. 27: 203-8. PMID 11943548 DOI: 10.1016/S0968-0004(02)02067-4 |
0.356 |
|
2001 |
Mattos C, Ringe D. Proteins in organic solvents. Current Opinion in Structural Biology. 11: 761-4. PMID 11751059 DOI: 10.1016/S0959-440X(01)00278-0 |
0.435 |
|
1999 |
Ringe D, Mattos C. Analysis of the binding surfaces of proteins. Medicinal Research Reviews. 19: 321-31. PMID 10398928 DOI: 10.1002/(Sici)1098-1128(199907)19:4<321::Aid-Med5>3.0.Co;2-F |
0.44 |
|
1998 |
MacKerell AD, Bashford D, Bellott M, Dunbrack RL, Evanseck JD, Field MJ, Fischer S, Gao J, Guo H, Ha S, Joseph-McCarthy D, Kuchnir L, Kuczera K, Lau FT, Mattos C, et al. All-atom empirical potential for molecular modeling and dynamics studies of proteins. The Journal of Physical Chemistry. B. 102: 3586-616. PMID 24889800 DOI: 10.1021/Jp973084F |
0.711 |
|
1996 |
Mattos C, Ringe D. Locating and Characterizing Binding Sites on Proteins Nature Biotechnology. 14: 595-599. PMID 9630949 DOI: 10.1038/Nbt0596-595 |
0.465 |
|
1996 |
Allen KN, Bellamacina CR, Ding X, Jeffery CJ, Mattos C, Petsko GA, Ringe D. An Experimental Approach to Mapping the Binding Surfaces of Crystalline Proteins† The Journal of Physical Chemistry. 100: 2605-2611. DOI: 10.1021/Jp952516O |
0.782 |
|
1995 |
Mattos C, Giammona DA, Petsko GA, Ringe D. Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors Biochemistry. 34: 3193-3203. PMID 7880814 DOI: 10.1021/Bi00010A008 |
0.557 |
|
1994 |
Mattos C, Petsko GA, Karplus M. Analysis of two-residue turns in proteins Journal of Molecular Biology. 238: 733-747. PMID 8182746 DOI: 10.1006/Jmbi.1994.1332 |
0.614 |
|
1994 |
Mattos C, Rasmussen B, Ding X, Petsko GA, Ringe D. Analogous inhibitors of elastase do not always bind analogously Nature Structural Biology. 1: 55-58. PMID 7656008 DOI: 10.1038/Nsb0194-55 |
0.548 |
|
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