Alfred H. Merrill - Publications

Affiliations: 
Georgia Institute of Technology, Atlanta, GA 
Area:
Analytical Chemistry, Biochemistry

283 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Alsanafi M, Kelly SL, McNaughton M, Merrill AH, Pyne NJ, Pyne S. The regulation of p53, p38 MAPK, JNK and XBP-1s by sphingosine kinases in human embryonic kidney cells. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 158631. PMID 31954175 DOI: 10.1016/j.bbalip.2020.158631  1
2019 Wan J, Li J, Bandyopadhyay S, Kelly SL, Xiang Y, Zhang J, Merrill A, Duan J. Analysis of 1-deoxysphingoid bases and their N-acyl-metabolites, and exploration of their occurrence in some food materials. Journal of Agricultural and Food Chemistry. PMID 31638789 DOI: 10.1021/acs.jafc.9b05708  1
2019 Melum E, Jiang X, Baker KD, Macedo MF, Fritsch J, Dowds CM, Wang J, Pharo A, Kaser A, Tan C, Pereira CS, Kelly SL, Duan J, Karlsen TH, Exley MA, ... ... Merrill AH, et al. Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. Nature Immunology. PMID 31636468 DOI: 10.1038/s41590-019-0504-0  1
2019 Riley RT, Merrill AH. Ceramide synthase inhibition by fumonisins: a perfect storm of perturbed sphingolipid metabolism, signaling and disease. Journal of Lipid Research. PMID 31048407 DOI: 10.1194/jlr.S093815  1
2018 Presa N, Clugston RD, Lingrell S, Kelly SE, Merrill AH, Jana S, Kassiri Z, Gómez-Muñoz A, Vance DE, Jacobs RL, van der Veen JN. Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1865: 14-25. PMID 30300671 DOI: 10.1016/j.bbadis.2018.10.010  1
2018 Alsanafi M, Kelly SL, Jubair K, McNaughton M, Tate RJ, Merrill AH, Pyne S, Pyne NJ. Native and polyubiquitinated forms of dihydroceramide desaturase are differentially linked to human embryonic kidney cell survival. Molecular and Cellular Biology. PMID 30224516 DOI: 10.1128/MCB.00222-18  1
2018 Tidhar R, Zelnik ID, Volpert G, Ben-Dor S, Kelly S, Merrill AH, Futerman AH. Eleven residues determine the acyl chain specificity of ceramide synthases. The Journal of Biological Chemistry. PMID 29632068 DOI: 10.1074/jbc.RA118.001936  1
2017 Saroha A, Pewzner-Jung Y, Ferreira NS, Sharma P, Jouan Y, Kelly SL, Feldmesser E, Merrill AH, Trottein F, Paget C, Lang KS, Futerman AH. Critical Role for Very-Long Chain Sphingolipids in Invariant Natural Killer T Cell Development and Homeostasis. Frontiers in Immunology. 8: 1386. PMID 29163475 DOI: 10.3389/fimmu.2017.01386  1
2017 Dasari SK, Bialik S, Levin-Zaidman S, Levin-Salomon V, Merrill AH, Futerman AH, Kimchi A. Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death. Cell Death and Differentiation. PMID 28574511 DOI: 10.1038/cdd.2017.80  1
2017 Ferreira NS, Engelsby H, Neess D, Kelly SL, Volpert G, Merrill AH, Futerman AH, Faergeman NJ. Regulation of very-long acyl chain ceramide synthesis by Acyl-CoA binding protein. The Journal of Biological Chemistry. PMID 28320857 DOI: 10.1074/jbc.M117.785345  1
2017 Volpert G, Ben-Dor S, Tarcic O, Duan J, Saada A, Merrill AH, Pewzner-Jung Y, Futerman AH. Oxidative stress elicited by modifying the ceramide acyl chain length reduces the rate of clathrin-mediated endocytosis. Journal of Cell Science. PMID 28280117 DOI: 10.1242/jcs.199968  1
2017 Merrill AH, Sullards MC. Opinion article on lipidomics: Inherent challenges of lipidomic analysis of sphingolipids. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 1862: 774-776. PMID 28161582 DOI: 10.1016/j.bbalip.2017.01.009  1
2017 Deevska GM, Dotson PP, Karakashian AA, Isaac G, Wrona M, Kelly SB, Merrill AH, Nikolova-Karakashian MN. Novel interconnections in lipid metabolism revealed by overexpression of sphingomyelin synthase-1. The Journal of Biological Chemistry. PMID 28087695 DOI: 10.1074/jbc.M116.751602  1
2016 Klein AD, Ferreira NS, Ben-Dor S, Duan J, Hardy J, Cox TM, Merrill AH, Futerman AH. Identification of Modifier Genes in a Mouse Model of Gaucher Disease. Cell Reports. PMID 27568557 DOI: 10.1016/j.celrep.2016.07.085  1
2016 Vardi A, Zigdon H, Meshcheriakova A, Klein AD, Yaacobi C, Eilam R, Kenwood BM, Rahim AA, Massaro G, Merrill AH, Vitner EB, Futerman AH. Delineating pathological pathways in a chemically-induced mouse model of Gaucher disease. The Journal of Pathology. PMID 27234572 DOI: 10.1002/path.4751  1
2015 Park WJ, Brenner O, Kogot-Levin A, Saada A, Merrill AH, Pewzner-Jung Y, Futerman AH. Development of pheochromocytoma in ceramide synthase 2 null mice. Endocrine-Related Cancer. 22: 623-32. PMID 26113602 DOI: 10.1530/ERC-15-0058  1
2015 Duan J, Merrill AH. 1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma. The Journal of Biological Chemistry. 290: 15380-9. PMID 25947379 DOI: 10.1074/jbc.R115.658823  1
2015 Merrill AH, Carman GM. Introduction to Thematic Minireview Series: Novel Bioactive Sphingolipids. The Journal of Biological Chemistry. 290: 15362-4. PMID 25947376 DOI: 10.1074/jbc.R115.663708  1
2015 Gorden DL, Myers DS, Ivanova PT, Fahy E, Maurya MR, Gupta S, Min J, Spann NJ, McDonald JG, Kelly SL, Duan J, Sullards MC, Leiker TJ, Barkley RM, Quehenberger O, ... ... Merrill AH, et al. Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Journal of Lipid Research. 56: 722-36. PMID 25598080 DOI: 10.1194/jlr.P056002  1
2015 Park WJ, Brenner O, Kogot-Levin A, Saada A, Merrill AH, Pewzner-Jung Y, Futerman AH. Development of pheochromocytoma in ceramide synthase 2 null mice Endocrine-Related Cancer. 22: 623-632. DOI: 10.1530/ERC-15-0058  1
2015 Duan J, Merrill AH. 1-deoxysphingolipids encountered exogenously and made de novo: Dangerous mysteries inside an enigma Journal of Biological Chemistry. 290: 15380-15389. DOI: 10.1074/jbc.R115.658823  1
2014 Jiménez-Rojo N, Sot J, Busto JV, Shaw WA, Duan J, Merrill AH, Alonso A, Goñi FM. Biophysical properties of novel 1-deoxy-(dihydro)ceramides occurring in mammalian cells. Biophysical Journal. 107: 2850-9. PMID 25517151 DOI: 10.1016/j.bpj.2014.10.010  1
2014 Park WJ, Park JW, Merrill AH, Storch J, Pewzner-Jung Y, Futerman AH. Hepatic fatty acid uptake is regulated by the sphingolipid acyl chain length. Biochimica Et Biophysica Acta. 1841: 1754-66. PMID 25241943 DOI: 10.1016/j.bbalip.2014.09.009  1
2014 Yamane D, McGivern DR, Wauthier E, Yi M, Madden VJ, Welsch C, Antes I, Wen Y, Chugh PE, McGee CE, Widman DG, Misumi I, Bandyopadhyay S, Kim S, Shimakami T, ... ... Merrill AH, et al. Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation. Nature Medicine. 20: 927-35. PMID 25064127 DOI: 10.1038/nm.3610  1
2014 Pinto SN, Laviad EL, Stiban J, Kelly SL, Merrill AH, Prieto M, Futerman AH, Silva LC. Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipid N-acyl chain. Journal of Lipid Research. 55: 53-61. PMID 24163422 DOI: 10.1194/jlr.M042002  1
2014 Farfel-Becker T, Vitner EB, Kelly SL, Bame JR, Duan J, Shinder V, Merrill AH, Dobrenis K, Futerman AH. Neuronal accumulation of glucosylceramide in a mouse model of neuronopathic Gaucher disease leads to neurodegeneration. Human Molecular Genetics. 23: 843-54. PMID 24064337 DOI: 10.1093/hmg/ddt468  1
2013 Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, ... ... Merrill AH, et al. 25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. The Journal of Biological Chemistry. 288: 35812-23. PMID 24189069 DOI: 10.1074/jbc.M113.519637  1
2013 Merrill AH, Dennis EA, McDonald JG, Fahy E. Lipidomics technologies at the end of the first decade and the beginning of the next. Advances in Nutrition (Bethesda, Md.). 4: 565-7. PMID 24038259 DOI: 10.3945/an.113.004333  1
2013 Park WJ, Park JW, Erez-Roman R, Kogot-Levin A, Bame JR, Tirosh B, Saada A, Merrill AH, Pewzner-Jung Y, Futerman AH. Protection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalization. The Journal of Biological Chemistry. 288: 30904-16. PMID 24019516 DOI: 10.1074/jbc.M112.448852  1
2013 Merrill AH, Murphy RC, Smith WL, Vance DE, Wilson JE, Yu RK. In memoriam: Charles (Chuck) Crawford Sweeley, Jr. (1930-2012). Journal of Lipid Research. 54: 1-4. PMID 23367521 DOI: 10.1194/jlr.E033993  1
2013 Zigdon H, Kogot-Levin A, Park JW, Goldschmidt R, Kelly S, Merrill AH, Scherz A, Pewzner-Jung Y, Saada A, Futerman AH. Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain. The Journal of Biological Chemistry. 288: 4947-56. PMID 23283968 DOI: 10.1074/jbc.M112.402719  1
2013 Morad SA, Messner MC, Levin JC, Abdelmageed N, Park H, Merrill AH, Cabot MC. Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells. Cancer Chemotherapy and Pharmacology. 71: 635-45. PMID 23263160 DOI: 10.1007/s00280-012-2050-4  1
2013 Merrill AH. Thematic review series on the living history of lipids Journal of Lipid Research. 54: 2945. DOI: 10.1194/jlr.E044164  1
2012 Molano A, Huang Z, Marko MG, Azzi A, Wu D, Wang E, Kelly SL, Merrill AH, Bunnell SC, Meydani SN. Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction. Plos One. 7: e47650. PMID 23110086 DOI: 10.1371/journal.pone.0047650  1
2012 Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, ... Merrill AH, et al. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 151: 138-52. PMID 23021221 DOI: 10.1016/j.cell.2012.06.054  1
2012 Martinez TN, Chen X, Bandyopadhyay S, Merrill AH, Tansey MG. Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons. Molecular Neurodegeneration. 7: 45. PMID 22973882 DOI: 10.1186/1750-1326-7-45  1
2012 Lucki NC, Li D, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB. Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor. Molecular and Cellular Biology. 32: 4419-31. PMID 22927646 DOI: 10.1128/MCB.00378-12  1
2012 Laviad EL, Kelly S, Merrill AH, Futerman AH. Modulation of ceramide synthase activity via dimerization. The Journal of Biological Chemistry. 287: 21025-33. PMID 22539345 DOI: 10.1074/jbc.M112.363580  1
2012 Abumrad NA, Piomelli D, Yurko-Mauro K, Merrill A, Clandinin MT, Serhan CN. Moving beyond "good fat, bad fat": the complex roles of dietary lipids in cellular function and health: session abstracts. Advances in Nutrition (Bethesda, Md.). 3: 60-8. PMID 22332103 DOI: 10.3945/an.111.000802  1
2012 Hagen-Euteneuer N, Lütjohann D, Park H, Merrill AH, van Echten-Deckert G. Sphingosine 1-phosphate (S1P) lyase deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neurons. The Journal of Biological Chemistry. 287: 9128-36. PMID 22291021 DOI: 10.1074/jbc.M111.302380  1
2012 Lucki NC, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB. Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression. Molecular Endocrinology (Baltimore, Md.). 26: 228-43. PMID 22261821 DOI: 10.1210/me.2011-1150  1
2012 Silva LC, Ben David O, Pewzner-Jung Y, Laviad EL, Stiban J, Bandyopadhyay S, Merrill AH, Prieto M, Futerman AH. Ablation of ceramide synthase 2 strongly affects biophysical properties of membranes. Journal of Lipid Research. 53: 430-6. PMID 22231783 DOI: 10.1194/jlr.M022715  1
2012 Tidhar R, Ben-Dor S, Wang E, Kelly S, Merrill AH, Futerman AH. Acyl chain specificity of ceramide synthases is determined within a region of 150 residues in the Tram-Lag-CLN8 (TLC) domain. The Journal of Biological Chemistry. 287: 3197-206. PMID 22144673 DOI: 10.1074/jbc.M111.280271  1
2011 Murphy RC, Merrill AH. Lipidomics and imaging mass spectrometry Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1811: 635-636. PMID 21983393 DOI: 10.1016/j.bbalip.2011.09.003  1
2011 Merrill AH. Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics Chemical Reviews. 111: 6387-6422. PMID 21942574 DOI: 10.1021/cr2002917  1
2011 Sullards MC, Liu Y, Chen Y, Merrill AH. Analysis of mammalian sphingolipids by liquid chromatography tandem mass spectrometry (LC-MS/MS) and tissue imaging mass spectrometry (TIMS). Biochimica Et Biophysica Acta. 1811: 838-53. PMID 21749933 DOI: 10.1016/j.bbalip.2011.06.027  1
2011 Ben-David O, Pewzner-Jung Y, Brenner O, Laviad EL, Kogot-Levin A, Weissberg I, Biton IE, Pienik R, Wang E, Kelly S, Alroy J, Raas-Rothschild A, Friedman A, Brügger B, Merrill AH, et al. Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels. The Journal of Biological Chemistry. 286: 30022-33. PMID 21705317 DOI: 10.1074/jbc.M111.261206  1
2011 Haynes CA, Allegood JC, Wang EW, Kelly SL, Sullards MC, Merrill AH. Factors to consider in using [U- 13C]palmitate for analysis of sphingolipid biosynthesis by tandem mass spectrometry Journal of Lipid Research. 52: 1583-1594. PMID 21586681 DOI: 10.1194/jlr.D015586  1
2011 Momin AA, Park H, Portz BJ, Haynes CA, Shaner RL, Kelly SL, Jordan IK, Merrill AH. A method for visualization of "omic" datasets for sphingolipid metabolism to predict potentially interesting differences. Journal of Lipid Research. 52: 1073-83. PMID 21415121 DOI: 10.1194/jlr.M010454  1
2011 Symolon H, Bushnev A, Peng Q, Ramaraju H, Mays SG, Allegood JC, Pruett ST, Sullards MC, Dillehay DL, Liotta DC, Merrill AH. Enigmol: A novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer Molecular Cancer Therapeutics. 10: 648-657. PMID 21398423 DOI: 10.1158/1535-7163.MCT-10-0754  1
2011 Quo CF, Moffitt RA, Merrill AH, Wang MD. Adaptive control model reveals systematic feedback and key molecules in metabolic pathway regulation. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 18: 169-82. PMID 21314456 DOI: 10.1089/cmb.2010.0215  1
2011 Gupta S, Maurya MR, Merrill AH, Glass CK, Subramaniam S. Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism. Bmc Systems Biology. 5: 26. PMID 21303545 DOI: 10.1186/1752-0509-5-26  1
2011 Dickson MA, Carvajal RD, Merrill AH, Gonen M, Cane LM, Schwartz GK. A phase I clinical trial of safingol in combination with cisplatin in advanced solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2484-92. PMID 21257722 DOI: 10.1158/1078-0432.CCR-10-2323  1
2010 Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH, Sullards MC, Wang E, Murphy RC, Raetz CR, et al. A mouse macrophage lipidome. The Journal of Biological Chemistry. 285: 39976-85. PMID 20923771 DOI: 10.1074/jbc.M110.182915  1
2010 Sims K, Haynes CA, Kelly S, Allegood JC, Wang E, Momin A, Leipelt M, Reichart D, Glass CK, Sullards MC, Merrill AH. Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. The Journal of Biological Chemistry. 285: 38568-79. PMID 20876532 DOI: 10.1074/jbc.M110.170621  1
2010 Chen Y, Liu Y, Sullards MC, Merrill AH. An introduction to sphingolipid metabolism and analysis by new technologies. Neuromolecular Medicine. 12: 306-19. PMID 20680704 DOI: 10.1007/s12017-010-8132-8  1
2010 Chen Y, Liu Y, Allegood J, Wang E, Cachón-González B, Cox TM, Merrill AH, Sullards MC. Imaging MALDI mass spectrometry of sphingolipids using an oscillating capillary nebulizer matrix application system Methods in Molecular Biology. 656: 131-146. PMID 20680588 DOI: 10.1007/978-1-60761-746-4_7  1
2010 Quehenberger O, Armando AM, Brown AH, Milne SB, Myers DS, Merrill AH, Bandyopadhyay S, Jones KN, Kelly S, Shaner RL, Sullards CM, Wang E, Murphy RC, Barkley RM, Leiker TJ, et al. Lipidomics reveals a remarkable diversity of lipids in human plasma. Journal of Lipid Research. 51: 3299-305. PMID 20671299 DOI: 10.1194/jlr.M009449  1
2010 Liu Y, Chen Y, Momin A, Shaner R, Wang E, Bowen NJ, Matyunina LV, Walker LD, McDonald JF, Sullards MC, Merrill AH. Elevation of sulfatides in ovarian cancer: an integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry. Molecular Cancer. 9: 186. PMID 20624317 DOI: 10.1186/1476-4598-9-186  1
2010 Andreyev AY, Fahy E, Guan Z, Kelly S, Li X, McDonald JG, Milne S, Myers D, Park H, Ryan A, Thompson BM, Wang E, Zhao Y, Brown HA, Merrill AH, et al. Subcellular organelle lipidomics in TLR-4-activated macrophages. Journal of Lipid Research. 51: 2785-97. PMID 20574076 DOI: 10.1194/jlr.M008748  1
2010 Pewzner-Jung Y, Brenner O, Braun S, Laviad EL, Ben-Dor S, Feldmesser E, Horn-Saban S, Amann-Zalcenstein D, Raanan C, Berkutzki T, Erez-Roman R, Ben-David O, Levy M, Holzman D, Park H, ... ... Merrill AH, et al. A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy. The Journal of Biological Chemistry. 285: 10911-23. PMID 20110366 DOI: 10.1074/jbc.M109.077610  1
2010 Pewzner-Jung Y, Park H, Laviad EL, Silva LC, Lahiri S, Stiban J, Erez-Roman R, Brügger B, Sachsenheimer T, Wieland F, Prieto M, Merrill AH, Futerman AH. A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways. The Journal of Biological Chemistry. 285: 10902-10. PMID 20110363 DOI: 10.1074/jbc.M109.077594  1
2010 Yin J, Miyazaki K, Shaner RL, Merrill AH, Kannagi R. Altered sphingolipid metabolism induced by tumor hypoxia - New vistas in glycolipid tumor markers Febs Letters. 584: 1872-1878. PMID 19913543 DOI: 10.1016/j.febslet.2009.11.019  1
2010 Park H, Haynes CA, Nairn AV, Kulik M, Dalton S, Moremen K, Merrill AH. Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies. Journal of Lipid Research. 51: 480-9. PMID 19786568 DOI: 10.1194/jlr.M000984  1
2009 Momin AA, Park H, Allegood JC, Leipelt M, Kelly SL, Merrill AH, Hanada K. Characterization of mutant serine palmitoyltransferase 1 in LY-B cells. Lipids. 44: 725-32. PMID 19536577 DOI: 10.1007/s11745-009-3316-4  1
2009 Goldfinger M, Laviad EL, Hadar R, Shmuel M, Dagan A, Park H, Merrill AH, Ringel I, Futerman AH, Tirosh B. De novo ceramide synthesis is required for N-linked glycosylation in plasma cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 7038-47. PMID 19454701 DOI: 10.4049/jimmunol.0802990  1
2009 Hu W, Bielawski J, Samad F, Merrill AH, Cowart LA. Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity Journal of Lipid Research. 50: 1852-1862. PMID 19369694 DOI: 10.1194/jlr.M800635-JLR200  1
2009 Wei J, Yerokun T, Leipelt M, Haynes CA, Radhakrishna H, Momin A, Kelly S, Park H, Wang E, Carton JM, Uhlinger DJ, Merrill AH. Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology. Biochimica Et Biophysica Acta. 1791: 746-56. PMID 19362163 DOI: 10.1016/j.bbalip.2009.03.016  1
2009 Hagen N, Van Veldhoven PP, Proia RL, Park H, Merrill AH, van Echten-Deckert G. Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons. The Journal of Biological Chemistry. 284: 11346-53. PMID 19251691 DOI: 10.1074/jbc.M807336200  1
2009 Coward J, Ambrosini G, Musi E, Truman JP, Haimovitz-Friedman A, Allegood JC, Wang E, Merrill AH, Schwartz GK. Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway. Autophagy. 5: 184-93. PMID 19098447 DOI: 10.4161/auto.5.2.7361  1
2009 Zitomer NC, Mitchell T, Voss KA, Bondy GS, Pruett ST, Garnier-Amblard EC, Liebeskind LS, Park H, Wang E, Sulllards MC, Merrill AH, Riley RT. Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine. A novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals Journal of Biological Chemistry. 284: 4786-4795. PMID 19095642 DOI: 10.1074/jbc.M808798200  1
2009 Deevska GM, Rozenova KA, Giltiay NV, Chambers MA, White J, Boyanovsky BB, Wei J, Daugherty A, Smart EJ, Reid MB, Merrill AH, Nikolova-Karakashian M. Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice. The Journal of Biological Chemistry. 284: 8359-68. PMID 19074137 DOI: 10.1074/jbc.M807800200  1
2009 Shaner RL, Allegood JC, Park H, Wang E, Kelly S, Haynes CA, Sullards MC, Merrill AH. Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers. Journal of Lipid Research. 50: 1692-707. PMID 19036716 DOI: 10.1194/jlr.D800051-JLR200  1
2009 Merrill AH, Stokes TH, Momin A, Park H, Portz BJ, Kelly S, Wang E, Sullards MC, Wang MD. Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease. Journal of Lipid Research. 50: S97-102. PMID 19029065 DOI: 10.1194/jlr.R800073-JLR200  1
2008 Siy PW, Moffitt RA, Parry RM, Chen Y, Liu Y, Sullards MC, Merrill AH, Wang MD. Matrix Factorization Techniques for Analysis of Imaging Mass Spectrometry Data. Proceedings. Ieee International Symposium On Bioinformatics and Bioengineering. 2008. PMID 28393151  1
2008 Kapoor S, Quo CF, Merrill AH, Wang MD. An interactive visualization tool and data model for experimental design in systems biology. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2008: 2423-6. PMID 19163191 DOI: 10.1109/IEMBS.2008.4649688  1
2008 Wang H, Maurer BJ, Liu YY, Wang E, Allegood JC, Kelly S, Symolon H, Liu Y, Merrill AH, Gouazé-Andersson V, Yu JY, Giuliano AE, Cabot MC. N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing. Molecular Cancer Therapeutics. 7: 2967-76. PMID 18790777 DOI: 10.1158/1535-7163.MCT-08-0549  1
2008 Machesky NJ, Zhang G, Raghavan B, Zimmerman P, Kelly SL, Merrill AH, Waldman WJ, Van Brocklyn JR, Trgovcich J. Human cytomegalovirus regulates bioactive sphingolipids. The Journal of Biological Chemistry. 283: 26148-60. PMID 18644793 DOI: 10.1074/jbc.M710181200  1
2008 Pruett ST, Bushnev A, Hagedorn K, Adiga M, Haynes CA, Sullards MC, Liotta DC, Merrill AH. Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols Journal of Lipid Research. 49: 1621-1639. PMID 18499644 DOI: 10.1194/jlr.R800012-JLR200  1
2008 Chen Y, Allegood J, Liu Y, Wang E, Cachón-González B, Cox TM, Merrill AH, Sullards MC. Imaging MALDI mass spectrometry using an oscillating capillary nebulizer matrix coating system and its application to analysis of lipids in brain from a mouse model of Tay-Sachs/Sandhoff disease Analytical Chemistry. 80: 2780-2788. PMID 18314967 DOI: 10.1021/ac702350g  1
2008 Haynes CA, Allegood JC, Sims K, Wang EW, Sullards MC, Merrill AH. Quantitation of fatty acyl-coenzyme As in mammalian cells by liquid chromatography-electrospray ionization tandem mass spectrometry Journal of Lipid Research. 49: 1113-1125. PMID 18287618 DOI: 10.1194/jlr.D800001-JLR200  1
2008 Laviad EL, Albee L, Pankova-Kholmyansky I, Epstein S, Park H, Merrill AH, Futerman AH. Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. The Journal of Biological Chemistry. 283: 5677-84. PMID 18165233 DOI: 10.1074/jbc.M707386200  1
2008 Siy PW, Moffitt RA, Parry RM, Chen Y, Liu Y, Sullards MC, Merrill AH, Wang MD. Matrix factorization techniques for analysis of imaging mass spectrometry data 8th Ieee International Conference On Bioinformatics and Bioengineering, Bibe 2008. DOI: 10.1109/BIBE.2008.4696797  1
2008 Merrill AH. Sphingolipids Biochemistry of Lipids, Lipoproteins and Membranes. 363-397. DOI: 10.1016/B978-044453219-0.50015-5  1
2007 Torres OA, Palencia E, Lopez de Pratdesaba L, Grajeda R, Fuentes M, Speer MC, Merrill AH, O'Donnell K, Bacon CW, Glenn AE, Riley RT. Estimated fumonisin exposure in Guatemala is greatest in consumers of lowland maize. The Journal of Nutrition. 137: 2723-9. PMID 18029490  1
2007 Dhingra S, Freedenberg M, Quo CF, Merrill AH, Wang MD. Computational modeling of a metabolic pathway in ceramide de novo synthesis. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2007: 1405-8. PMID 18002227 DOI: 10.1109/IEMBS.2007.4352561  1
2007 Sullards MC, Allegood JC, Kelly S, Wang E, Haynes CA, Park H, Chen Y, Merrill AH. Structure-specific, quantitative methods for analysis of sphingolipids by liquid chromatography-tandem mass spectrometry: "inside-out" sphingolipidomics. Methods in Enzymology. 432: 83-115. PMID 17954214 DOI: 10.1016/S0076-6879(07)32004-1  1
2007 Merrill AH, Wang MD, Park M, Sullards MC. (Glyco)sphingolipidology: an amazing challenge and opportunity for systems biology. Trends in Biochemical Sciences. 32: 457-68. PMID 17928229 DOI: 10.1016/j.tibs.2007.09.004  1
2007 Wu D, Ren Z, Pae M, Guo W, Cui X, Merrill AH, Meydani SN. Aging up-regulates expression of inflammatory mediators in mouse adipose tissue Journal of Immunology. 179: 4829-4839. PMID 17878382  1
2007 Seiferlein M, Humpf HU, Voss KA, Sullards MC, Allegood JC, Wang E, Merrill AH. Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites Molecular Nutrition and Food Research. 51: 1120-1130. PMID 17729221 DOI: 10.1002/mnfr.200700118  1
2007 Li D, Urs AN, Allegood J, Leon A, Merrill AH, Sewer MB. Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17. Molecular and Cellular Biology. 27: 6669-85. PMID 17664281 DOI: 10.1128/MCB.00355-07  1
2007 Morales PR, Dillehay DL, Moody SJ, Pallas DC, Pruett S, Allgood JC, Symolon H, Merrill AH. Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation. Drug and Chemical Toxicology. 30: 197-216. PMID 17613006 DOI: 10.1080/01480540701375018  1
2007 Rao RP, Yuan C, Allegood JC, Rawat SS, Edwards MB, Wang X, Merrill AH, Acharya U, Acharya JK. Ceramide transfer protein function is essential for normal oxidative stress response and lifespan. Proceedings of the National Academy of Sciences of the United States of America. 104: 11364-9. PMID 17592126 DOI: 10.1073/pnas.0705049104  1
2007 Lamour NF, Stahelin RV, Wijesinghe DS, Maceyka M, Wang E, Allegood JC, Merrill AH, Cho W, Chalfant CE. Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis. Journal of Lipid Research. 48: 1293-304. PMID 17392267 DOI: 10.1194/jlr.M700083-JLR200  1
2007 Finnegan CM, Rawat SS, Cho EH, Guiffre DL, Lockett S, Merrill AH, Blumenthal R. Sphingomyelinase restricts the lateral diffusion of CD4 and inhibits human immunodeficiency virus fusion. Journal of Virology. 81: 5294-304. PMID 17344303 DOI: 10.1128/JVI.02553-06  1
2007 Urs AN, Dammer E, Kelly S, Wang E, Merrill AH, Sewer MB. Steroidogenic factor-1 is a sphingolipid binding protein. Molecular and Cellular Endocrinology. 265: 174-8. PMID 17196738 DOI: 10.1016/j.mce.2006.12.016  1
2007 Sud M, Fahy E, Cotter D, Brown A, Dennis EA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Subramaniam S. LMSD: LIPID MAPS structure database. Nucleic Acids Research. 35: D527-32. PMID 17098933 DOI: 10.1093/nar/gkl838  1
2007 Brimble SN, Sherrer ES, Uhl EW, Wang E, Kelly S, Merrill AH, Robins AJ, Schulz TC. The cell surface glycosphingolipids SSEA-3 and SSEA-4 are not essential for human ESC pluripotency. Stem Cells (Dayton, Ohio). 25: 54-62. PMID 17008424 DOI: 10.1634/stemcells.2006-0232  1
2007 Muir ER, Ndiour IJ, Le Goasduff NA, Moffitt RA, Liu Y, Sullards MC, Merrill AH, Chen Y, Wang MD. Multivariate analysis of imaging mass spectrometry data Proceedings of the 7th Ieee International Conference On Bioinformatics and Bioengineering, Bibe. 472-479. DOI: 10.1109/BIBE.2007.4375603  1
2006 Fox TE, Han X, Kelly S, Merrill AH, Martin RE, Anderson RE, Gardner TW, Kester M. Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy. Diabetes. 55: 3573-80. PMID 17130506 DOI: 10.2337/db06-0539  1
2006 Linn SC, Andras LM, Kim HS, Wei J, Nagiec MM, Dickson RC, Merrill AH. Functional characterization of the promoter for the mouse SPTLC2 gene, which encodes subunit 2 of serine palmitoyltransferase. Febs Letters. 580: 6217-23. PMID 17070807 DOI: 10.1016/j.febslet.2006.10.025  1
2006 Zheng W, Kollmeyer J, Symolon H, Momin A, Munter E, Wang E, Kelly S, Allegood JC, Liu Y, Peng Q, Ramaraju H, Sullards MC, Cabot M, Merrill AH. Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy. Biochimica Et Biophysica Acta. 1758: 1864-84. PMID 17052686 DOI: 10.1016/j.bbamem.2006.08.009  1
2006 Dragusin M, Wehner S, Kelly S, Wang E, Merrill AH, Kalff JC, van Echten-Deckert G. Effects of sphingosine-1-phosphate and ceramide-1-phosphate on rat intestinal smooth muscle cells: implications for postoperative ileus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1930-2. PMID 16877527 DOI: 10.1096/fj.05-5518fje  1
2006 Giussani P, Maceyka M, Le Stunff H, Mikami A, Lépine S, Wang E, Kelly S, Merrill AH, Milstien S, Spiegel S. Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide. Molecular and Cellular Biology. 26: 5055-69. PMID 16782891 DOI: 10.1128/MCB.02107-05  1
2006 Rittershaus PC, Kechichian TB, Allegood JC, Merrill AH, Hennig M, Luberto C, Del Poeta M. Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans. The Journal of Clinical Investigation. 116: 1651-9. PMID 16741577 DOI: 10.1172/JCI27890  1
2006 Dougherty AM, McDonald FE, Liotta DC, Moody SJ, Pallas DC, Pack CD, Merrill AH. Synthesis of 1-deoxysphingosine derivatives with conformationally restricted pyrrolidinediol head groups. Organic Letters. 8: 649-52. PMID 16468733 DOI: 10.1021/ol052839v  1
2006 Missmer SA, Suarez L, Felkner M, Wang E, Merrill AH, Rothman KJ, Hendricks KA. Exposure to fumonisins and the occurrence of neural tube defects along the Texas-Mexico border. Environmental Health Perspectives. 114: 237-41. PMID 16451860 DOI: 10.1289/ehp.8221  1
2006 Curfman CL, Kirkland K, Merrill AH. Recent anticancer agents targeting sphingolipid pathways Expert Opinion On Therapeutic Patents. 16: 1129-1147. DOI: 10.1517/13543776.16.8.1129  1
2006 Hong JY, Allegood JC, Kelly S, Wang E, Merrill AH, Wang MD. A computer visualization model for the de novo sphingolipid biosynthetic pathway Sphingolipid Biology. 493-508. DOI: 10.1007/4-431-34200-1_39  1
2006 Wei J, Yerokun T, Liepelt M, Momin A, Wang E, Hanada K, Merrill AH. Serine palmitoyltransferase Sphingolipid Biology. 25-47. DOI: 10.1007/4-431-34200-1_2  1
2006 Hirabayashi Y, Igarashi Y, Merrill AH. Sphingolipids synthesis, transport and cellular signaling Sphingolipid Biology. 3-22. DOI: 10.1007/4-431-34200-1_1  1
2006 Hirabayashi Y, Igarashi Y, Merrill AH. Sphingolipid biology Sphingolipid Biology. 1-531. DOI: 10.1007/4-431-34200-1  1
2005 Maceyka M, Sankala H, Hait NC, Le Stunff H, Liu H, Toman R, Collier C, Zhang M, Satin LS, Merrill AH, Milstien S, Spiegel S. SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism. The Journal of Biological Chemistry. 280: 37118-29. PMID 16118219 DOI: 10.1074/jbc.M502207200  1
2005 Merrill AH. SphinGOMAP - A web-based biosynthetic pathway map of sphingolipids and glycosphingolipids [1] Glycobiology. 15. PMID 15938018 DOI: 10.1093/glycob/cwi070  1
2005 Merrill AH, Sullards MC, Allegood JC, Kelly S, Wang E. Sphingolipidomics: High-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry Methods. 36: 207-224. PMID 15894491 DOI: 10.1016/j.ymeth.2005.01.009  1
2005 Fahy E, Subramaniam S, Brown HA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Seyama Y, Shaw W, Shimizu T, Spener F, van Meer G, VanNieuwenhze MS, White SH, et al. A comprehensive classification system for lipids. Journal of Lipid Research. 46: 839-61. PMID 15722563 DOI: 10.1194/jlr.E400004-JLR200  1
2005 Henning PA, Moffitt RA, Allegood JC, Wang E, Merrill AH, Wang MD. Computationally predicting rate constants in pathway models Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 7: 5093-5096.  1
2004 Henning PA, Merrill AH, Wang MD. Dynamic pathway modeling of sphingolipid metabolism. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 4: 2913-6. PMID 17270887 DOI: 10.1109/IEMBS.2004.1403828  1
2004 Ozbay T, Merrill AH, Sewer MB. ACTH regulates steroidogenic gene expression and cortisol biosynthesis in the human adrenal cortex via sphingolipid metabolism. Endocrine Research. 30: 787-94. PMID 15666826 DOI: 10.1081/ERC-200044040  1
2004 Monick MM, Mallampalli RK, Bradford M, McCoy D, Gross TJ, Flaherty DM, Powers LS, Cameron K, Kelly S, Merrill AH, Hunninghake GW. Cooperative prosurvival activity by ERK and Akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity. Journal of Immunology (Baltimore, Md. : 1950). 173: 123-35. PMID 15210766 DOI: 10.4049/jimmunol.173.1.123  1
2004 Symolon H, Schmelz EM, Dillehay DL, Merrill AH. Dietary Soy Sphingolipids Suppress Tumorigenesis and Gene Expression in 1,2-Dimethylhydrazine-Treated CF1 Mice and ApcMin/+ Mice Journal of Nutrition. 134: 1157-1161. PMID 15113963  1
2004 Marasas WF, Riley RT, Hendricks KA, Stevens VL, Sadler TW, Gelineau-van Waes J, Missmer SA, Cabrera J, Torres O, Gelderblom WC, Allegood J, Martínez C, Maddox J, Miller JD, Starr L, ... ... Merrill AH, et al. Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize. The Journal of Nutrition. 134: 711-6. PMID 15051815 DOI: 10.1093/jn/134.4.711  1
2004 Dedov VN, Dedova IV, Merrill AH, Nicholson GA. Activity of partially inhibited serine palmitoyltransferase is sufficient for normal sphingolipid metabolism and viability of HSN1 patient cells. Biochimica Et Biophysica Acta. 1688: 168-75. PMID 14990347 DOI: 10.1016/j.bbadis.2003.12.005  1
2004 Reiss U, Oskouian B, Zhou J, Gupta V, Sooriyakumaran P, Kelly S, Wang E, Merrill AH, Saba JD. Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis. The Journal of Biological Chemistry. 279: 1281-90. PMID 14570870 DOI: 10.1074/jbc.M309646200  1
2004 Henning PA, Merrill AH, Wang MD. Dynamic pathway modeling of sphingolipid metabolism Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 26: 2913-2916.  1
2003 Sullards MC, Wang E, Peng Q, Merrill AH. Metabolomic profiling of sphingolipids in human glioma cell lines by liquid chromatography tandem mass spectrometry Cellular and Molecular Biology (Noisy-Le-Grand, France). 49: 789-797. PMID 14528916  1
2003 Riebeling C, Allegood JC, Wang E, Merrill AH, Futerman AH. Two Mammalian Longevity Assurance Gene (LAG1) Family Members, trh1 and trh4, Regulate Dihydroceramide Synthesis Using Different Fatty Acyl-CoA Donors Journal of Biological Chemistry. 278: 43452-43459. PMID 12912983 DOI: 10.1074/jbc.M307104200  1
2003 Menaldino DS, Bushnev A, Sun A, Liotta DC, Symolon H, Desai K, Dillehay DL, Peng Q, Wang E, Allegood J, Trotman-Pruett S, Sullards MC, Merrill AH. Sphingoid bases and de novo ceramide synthesis: Enzymes involved, pharmacology and mechanisms of action Pharmacological Research. 47: 373-381. PMID 12676511 DOI: 10.1016/S1043-6618(03)00054-9  1
2002 Desai K, Sullards MC, Allegood J, Wang E, Schmelz EM, Hartl M, Humpf HU, Liotta DC, Peng Q, Merrill AH. Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1585: 188-192. PMID 12531553 DOI: 10.1016/S1388-1981(02)00340-2  1
2002 Patten Hitt E, DeLong MJ, Merrill AH. Benzo(a)pyrene activates extracellular signal-related and p38 mitogen-activated protein kinases in HT29 colon adenocarcinoma cells: involvement in NAD(P)H:quinone reductase activity and cell proliferation. Toxicology and Applied Pharmacology. 183: 160-7. PMID 12383707 DOI: 10.1006/taap.2002.9483  1
2002 Sadler TW, Merrill AH, Stevens VL, Sullards MC, Wang E, Wang P. Prevention of fumonisin B1-induced neural tube defects by folic acid Teratology. 66: 169-176. PMID 12353213 DOI: 10.1002/tera.10089  1
2002 Venkataraman K, Riebeling C, Bodennec J, Riezman H, Allegood JC, Sullards MC, Merrill AH, Futerman AH. Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. The Journal of Biological Chemistry. 277: 35642-9. PMID 12105227 DOI: 10.1074/jbc.M205211200  1
2002 Smith WL, Merrill AH. Sphingolipid metabolism and signaling minireview series Journal of Biological Chemistry. 277: 25841-25842. PMID 12048220 DOI: 10.1074/jbc.R200011200  1
2002 Merrill AH. De novo sphingolipid biosynthesis: A necessary, but dangerous, pathway Journal of Biological Chemistry. 277: 25843-25846. PMID 12011104 DOI: 10.1074/jbc.R200009200  1
2002 Merrill AH, Sandhoff K. Chapter 14 Sphingolipids: metabolism and cell signaling New Comprehensive Biochemistry. 36: 373-407.  1
2002 Allegood J, Wang E, Sullards MC, Merrill AH. Analysis of fumonisins and modified fumonisins by liquid chromatography tandem mass spectrometry (LC-MS/MS) Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 609-610.  1
2002 Sullards MC, Linn S, Andras L, Wang E, Merrill AH. Identification and quantitation of complex mixtures of sphingolipids by LC-MS/MS Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 603-604.  1
2002 Trotman SE, Symolon HE, Sullards MC, Menaldino DC, Liotta DC, Merrill AH. LC-MS/MS of endogenous and synthetic sphingolipids Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 591-592.  1
2001 Sullards MC, Merrill AH. Analysis of sphingosine 1-phosphate, ceramides, and other bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry Science"S Stke [Electronic Resource] : Signal Transduction Knowledge Environment. 2001. PMID 11752637  1
2001 Riley RT, Enongene E, Voss KA, Norred WP, Meredith FI, Sharma RP, Spitsbergen J, Williams DE, Carlson DB, Merrill AH. Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. Environmental Health Perspectives. 109: 301-8. PMID 11359699 DOI: 10.1289/ehp.01109s2301  1
2001 Merrill AH, Sullards MC, Wang E, Voss KA, Riley RT. Sphingolipid metabolism: Roles in signal transduction and disruption by fumonisins Environmental Health Perspectives. 109: 283-289. PMID 11359697  1
2000 Caligan TB, Peters K, Ou J, Wang E, Saba J, Merrill AH. A high-performance liquid chromatographic method to measure sphingosine 1-phosphate and related compounds from sphingosine kinase assays and other biological samples Analytical Biochemistry. 281: 36-44. PMID 10847608 DOI: 10.1006/abio.2000.4555  1
2000 Sullards MC, Lynch DV, Merrill AH, Adams J. Structure determination of soybean and wheat glucosylceramides by tandem mass spectrometry Journal of Mass Spectrometry. 35: 347-353. PMID 10767763 DOI: 10.1002/(SICI)1096-9888(200003)35:3<347::AID-JMS941>3.0.CO;2-3  1
2000 Grullich C, Sullards MC, Fuks Z, Merrill AH, Kolesnick R. CD95(Fas/APO-1) signals ceramide generation independent of the effector stage of apoptosis Journal of Biological Chemistry. 275: 8650-8656. PMID 10722705 DOI: 10.1074/jbc.275.12.8650  1
2000 Merrill AH, Bowman BB, Preusch PC. Mechanistic aspects of vitamin and coenzyme utilization and function: a symposium in recognition of the distinguished career of Donald B. McCormick. The Journal of Nutrition. 130: 321S-322S. PMID 10721896  1
2000 Schmelz EM, Sullards MC, Dillehay DL, Merrill AH. Colonic cell proliferation and aberrant crypt foci formation are inhibited by dairy glycosphingolipids in 1,2-dimethylhydrazine-treated CF1 mice Journal of Nutrition. 130: 522-527. PMID 10702579  1
1999 Riley RT, Norred WP, Wang E, Merrill AH. Alteration in sphingolipid metabolism: Bioassays for fumonisin- and ISP-I-like activity in tissues, cells and other matrices Natural Toxins. 7: 407-414. PMID 11122537 DOI: 10.1002/1522-7189(199911/12)7:6<407::AID-NT84>3.0.CO;2-0  1
1999 Merrill AH, Nikolova-Karakashian M, Schmelz EM, Morgan ET, Stewart J. Regulation of cytochrome P450 expression by sphingolipids Chemistry and Physics of Lipids. 102: 131-139. PMID 11001567 DOI: 10.1016/S0009-3084(99)00081-X  1
1999 Merrill AH, Morgan ET, Nikolova-Karakashian M, Stewart J. Sphingomyelin hydrolysis and regulation of the expression of the gene for cytochrome P450 Biochemical Society Transactions. 27: 383-387. PMID 10917607  1
1999 Schmelz EM, Bushnev AS, Dillehay DL, Sullards MC, Liotta DC, Merrill AH. Ceramide-β-D-glucuronide: Synthesis, digestion, and suppression of early markers of colon carcinogenesis Cancer Research. 59: 5768-5772. PMID 10582697  1
1999 Warden LA, Menaldino DS, Wilson T, Liotta DC, Smith ER, Merrill AH. Identification of ammonium ion and 2,6-bis(ω-aminobutyl)-3,5- diiminopiperazine as endogenous factors that account for the 'burst' of sphingosine upon changing the medium of J774 cells in culture Journal of Biological Chemistry. 274: 33875-33880. PMID 10567348 DOI: 10.1074/jbc.274.48.33875  1
1999 Nikolova-Karakashian M, Merrill AH. Ceramidases Methods in Enzymology. 311: 194-201. PMID 10563325 DOI: 10.1016/S0076-6879(00)11081-X  1
1999 Wang E, Merrill AH. Ceramide synthase Methods in Enzymology. 311: 15-21. PMID 10563306 DOI: 10.1016/S0076-6879(00)11062-6  1
1999 Meredith FI, Torres OR, De Tejada SS, Riley RT, Merrill AH. Fumonisin B1 and hydrolyzed fumonisin B1 (AP1) in tortillas and nixtamalized corn (Zea mays L.) from Two different geographic locations in Guatemala Journal of Food Protection. 62: 1218-1222. PMID 10528731 DOI: 10.4315/0362-028X-62.10.1218  1
1999 Vesper H, Schmelz EM, Nikolova-Karakashian MN, Dillehay DL, Lynch DV, Merrill AH. Sphingolipids in food and the emerging importance of sphingolipids to nutrition. The Journal of Nutrition. 129: 1239-50. PMID 10395583 DOI: 10.1093/jn/129.7.1239  1
1999 Wang E, Riley RT, Meredith FI, Merrill AH. Fumonisin B1 consumption by rats causes reversible, dose-dependent increases in urinary sphinganine and sphingosine Journal of Nutrition. 129: 214-220. PMID 9915902  1
1998 Birt DF, Merrill AH, Barnett T, Enkvetchakul B, Pour PM, Liotta DC, Geisler V, Menaldino DS, Schwartzbauer J. Inhibition of skin carcinomas but not papillomas by sphingosine, N- methylsphingosine, and N-acetylsphingosine Nutrition and Cancer. 31: 119-126. PMID 9770723  1
1998 Norred WP, Voss KA, Riley RT, Meredith FI, Bacon CW, Merrill AH. Mycotoxins and health hazards: Toxicological aspects and mechanism of action of fumonisins Journal of Toxicological Sciences. 23: 160-164. PMID 9760455  1
1998 Ciacci-Zanella JR, Merrill AH, Wang E, Jones C. Characterization of cell-cycle arrest by fumonisin B1 in CV-1 cells Food and Chemical Toxicology. 36: 791-804. PMID 9737426 DOI: 10.1016/S0278-6915(98)00034-9  1
1998 Humpf HU, Schmelz EM, Meredith FI, Vesper H, Vales TR, Wang E, Menaldino DS, Liotta DC, Merrill AH. Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase: Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor Journal of Biological Chemistry. 273: 19060-19064. PMID 9668088 DOI: 10.1074/jbc.273.30.19060  1
1998 Schmelz EM, Dombrink-Kurtzman MA, Roberts PC, Kozutsumi Y, Kawasaki T, Merrill AH. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases Toxicology and Applied Pharmacology. 148: 252-260. PMID 9473533 DOI: 10.1006/taap.1997.8356  1
1998 Abbas HK, Duke SO, Merrill AH, Wang E, Shier WT. Phytotoxicity of Australifungin, AAL-toxins and fumonisin B1 to Lemna pausicostata Phytochemistry. 47: 1509-1514. DOI: 10.1016/S0031-9422(97)00781-4  1
1997 Nikolova-Karakashian MN, Russell RW, Booth RA, Jenden DJ, Merrill AH. Sphingomyelin metabolism in rat liver after chronic dietary replacement of choline by N-aminodeanol. Journal of Lipid Research. 38: 1764-70. PMID 9323586  1
1997 Michel C, Van Echten-Deckert G, Rother J, Sandhoff K, Wang E, Merrill AH. Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide Journal of Biological Chemistry. 272: 22432-22437. PMID 9312549 DOI: 10.1074/jbc.272.36.22432  1
1997 Kok JW, Nikolova-Karakashian M, Klappe K, Alexander C, Merrill AH. Dihydroceramide biology. Structure-specific metabolism and intracellular localization Journal of Biological Chemistry. 272: 21128-21136. PMID 9261117 DOI: 10.1074/jbc.272.34.21128  1
1997 Nikolova-Karakashian M, Morgan ET, Alexander C, Liotta DC, Merrill AH. Bimodal regulation of ceramidase by interleukin-1β. Implications for the regulation of cytochrome P450 2C11 (CYP2C11) Journal of Biological Chemistry. 272: 18718-18724. PMID 9228043 DOI: 10.1074/jbc.272.30.18718  1
1997 Schmelz EM, Bushnev AS, Dillehay DL, Liotta DC, Merrill AH. Suppression of aberrant colonic crypt foci by synthetic sphingomyelins with saturated or unsaturated sphingoid base backbones. Nutrition and Cancer. 28: 81-5. PMID 9200154 DOI: 10.1080/01635589709514556  1
1997 Smith ER, Jones PL, Boss JM, Merrill AH. Changing J774A.1 cells to new medium perturbs multiple signaling pathways, including the modulation of protein kinase C by endogenous sphingoid bases Journal of Biological Chemistry. 272: 5640-5646. PMID 9038174 DOI: 10.1074/jbc.272.9.5640  1
1997 Merrill AH, Schmelz EM, Dillehay DL, Spiegel S, Shayman JA, Schroeder JJ, Riley RT, Voss KA, Wang E. Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology. Toxicology and Applied Pharmacology. 142: 208-25. PMID 9007051 DOI: 10.1006/taap.1996.8029  1
1996 Merrill AH, Liotta DC, Riley RT. Fumonisins: fungal toxins that shed light on sphingolipid function. Trends in Cell Biology. 6: 218-23. PMID 15157459 DOI: 10.1016/0962-8924(96)10021-0  1
1996 Spiegel S, Merrill AH. Sphingolipid metabolism and cell growth regulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 1388-97. PMID 8903509  1
1996 Schmelz EM, Dillehay DL, Webb SK, Reiter A, Adams J, Merrill AH. Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas versus adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine: Implications for dietary sphingolipids and colon carcinogenesis Cancer Research. 56: 4936-4941. PMID 8895747  1
1996 Merrill AH, Wang E, Vales TR, Smith ER, Schroeder JJ, Menaldino DS, Alexander C, Crane HM, Xia J, Liotta DC, Meredith FI, Riley RT. Fumonisin toxicity and sphingolipid biosynthesis. Advances in Experimental Medicine and Biology. 392: 297-306. PMID 8850625  1
1996 Morgan ET, Nikolova-Karakashian M, Chen JQ, Merrill AH. Sphingolipid-dependent signaling in regulation of cytochrome P450 expression Methods in Enzymology. 272: 381-388. PMID 8791797  1
1996 Zacharias C, Van Echten-Deckert G, Wang E, Merrill AH, Sandhoff K. The effect of fumonisin B1 on developing chick embryos: Correlation between de novo sphingolipid biosynthesis and gross morphological changes Glycoconjugate Journal. 13: 167-175. PMID 8737241 DOI: 10.1007/BF00731491  1
1996 Merrill AH, Liotta DC, Riley RT. Sphingolipids as regulators of cellular growth, differentiation, and behavior Advances in Lipobiology. 1: 273-298. DOI: 10.1016/S1874-5245(96)80012-7  1
1996 Merrill AH. Activation of ceramide hydrolysis by il-1β in rat hepatocytes Faseb Journal. 10.  1
1996 Schroeder JJ, Merrill AH. Stereospecfflcity of calcium mobilization by sphinganine and augmentation by fumonisin B1 Faseb Journal. 10.  1
1996 Schmelz M, Merrill AH. Altered sphingolipid composition in HT29 cells. Eva Faseb Journal. 10.  1
1996 Schmelz EM, Dombrink-Kurtzman MA, Merrill AH. Fumonisin bi toxicity for HT29 cells is reduced by removal of the tricarballylic sidechains Faseb Journal. 10.  1
1995 Pushkareva M, Chao R, Bielawska A, Merrill AH, Crane HM, Lagu B, Liotta D, Hannun YA. Stereoselectivity of induction of the retinoblastoma gene product (pRb) dephosphorylation by D-erythro-sphingosine supports a role for pRb in growth suppression by sphingosine. Biochemistry. 34: 1885-92. PMID 7849048 DOI: 10.1021/bi00006a009  1
1995 Merrill AH, Schmelz EM, Wang E, Schroeder JJ, Dillehay DL, Riley RT. Role of dietary sphingolipids and inhibitors of sphingolipid metabolism in cancer and other diseases Journal of Nutrition. 125. PMID 7782925  1
1995 Wu WI, McDonough VM, Nickels JT, Ko J, Fischl AS, Vales TR, Merrill AH, Carman GM. Regulation of lipid biosynthesis in Saccharomyces cerevisiae by fumonisin B1 Journal of Biological Chemistry. 270: 13171-13178. PMID 7768913 DOI: 10.1074/jbc.270.22.13171  1
1995 Ramasamy S, Wang E, Hennig B, Merrill AH. Fumonisin B1 alters sphingolipid metabolism and disrupts the barrier function of endothelial cells in culture Toxicology and Applied Pharmacology. 133: 343-348. PMID 7645031 DOI: 10.1006/taap.1995.1159  1
1995 Smith ER, Merrill AH. Differential roles of de Novo sphingolipid biosynthesis and turnover in the "Burst" of free sphingosine and sphinganine, and their 1-phosphates and N-Acyl-derivatives, that occurs upon changing the medium of cells in culture Journal of Biological Chemistry. 270: 18749-18758. PMID 7642524  1
1995 Restum JC, Bursian SJ, Millerick M, Render JA, Merrill AH, Wang E, Rottinghaus GE, Aulerich RJ. Chronic toxicity of fumonisins from Fusarium moniliforme culture material (M-1325) to mink. Archives of Environmental Contamination and Toxicology. 29: 545-50. PMID 7574884 DOI: 10.1007/BF00208387  1
1995 Martinova EA, Merrill AH. Fumonisin B1 alters sphingolipid metabolism and immune function in BALB/c mice: Immunological responses to fumonisin B1 Mycopathologia. 130: 163-170. PMID 7566070 DOI: 10.1007/BF01103100  1
1995 Chen J, Nikolova-Karakashian M, Merrill AH, Morgan ET. Regulation of cytochrome P450 2C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes Journal of Biological Chemistry. 270: 25233-25238. PMID 7559661 DOI: 10.1074/jbc.270.42.25233  1
1994 Riley RT, Voss KA, Yoo HS, Gelderblom WCA, Merrill AH. Mechanism of Fumonisin Toxicity and Carcinogenesis. Journal of Food Protection. 57: 638-644. PMID 31121715 DOI: 10.4315/0362-028X-57.7.638  1
1994 Schmelz EM, Crall KJ, Larocque R, Dillehay DL, Merrill AH. Uptake and metabolism of sphingolipids in isolated intestinal loops of mice Journal of Nutrition. 124: 702-712. PMID 8169662  1
1994 Dillehay DL, Webb SK, Schmelz EM, Merrill AH. Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice Journal of Nutrition. 124: 615-620. PMID 8169652  1
1994 Riley RT, Hinton DM, Chamberlain WJ, Bacon CW, Wang E, Merrill AH, Voss KA. Dietary fumonisin B1 induces disruption of sphingolipid metabolism in Sprague-Dawley rats: A new mechanism of nephrotoxicity Journal of Nutrition. 124: 594-603. PMID 8145083 DOI: 10.1093/jn/124.4.594  1
1994 Schroeder JJ, Crane HM, Xia J, Liotta DC, Merrill AH. Disruption of sphingolipid metabolism and stimulation of DNA synthesis by fumonisin B1. A molecular mechanism for carcinogenesis associated with Fusarium moniliforme. The Journal of Biological Chemistry. 269: 3475-81. PMID 8106389  1
1993 Zhang Z, Smith E, Surowiec SM, Merrill AH, McCormick DB. Synthesis of n-(4'pyridoxyl)sphingosine and its uptake and metabolism by isolated cells Molecular Membrane Biology. 10: 53-59. PMID 8510562 DOI: 10.3109/09687689309150252  1
1993 Merrill AH, Wang E, Gilchrist DG, Riley RT. Fumonisins and other inhibitors of de novo sphingolipid biosynthesis Advances in Lipid Research. 26: 215-234. PMID 8379451  1
1993 Merrill AH, Schroeder JJ. Lipid modulation of cell function Annual Review of Nutrition. 13: 539-559. PMID 8369158  1
1993 Merrill AH, Hannun YA, Bell RM. Introduction: sphingolipids and their metabolites in cell regulation Advances in Lipid Research. 25: 1-24. PMID 8368146  1
1993 Merrill AH. Comment by A. H. Merrill, Associate Editor [2] Journal of Nutrition. 123: 1605. PMID 8360787 DOI: 10.1093/jn/123.9.1605  1
1993 Wu WI, Lin YP, Wang E, Merrill AH, Carman GM. Regulation of phosphatidate phosphatase activity from the yeast Saccharomyces cerevisiae by sphingoid bases Journal of Biological Chemistry. 268: 13830-13837. PMID 8314751  1
1993 Borek C, Merrill AH. Sphingolipids inhibit multistage carcinogenesis and protein kinase C. Basic Life Sciences. 61: 367-71. PMID 8304947  1
1993 Merrill AH, Van Echten G, Wang E, Sandhoff K. Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ Journal of Biological Chemistry. 268: 27299-27306. PMID 8262970  1
1993 Merrill AH. Apo A-IV: A new satiety signal Nutrition Reviews. 51: 273-275. PMID 8247420  1
1992 Wang E, Ross PF, Wilson TM, Riley RT, Merrill AH. Increases in serum sphingosine and sphinganine and decreases in complex sphingolipids in ponies given feed containing fumonisins, mycotoxins produced by Fusarium moniliforme Journal of Nutrition. 122: 1706-1716. PMID 1640265  1
1992 Yoo HS, Norred WP, Wang E, Merrill AH, Riley RT. Fumonisin inhibition of de Novo sphingolipid biosynthesis and cytotoxicity are correlated in LLC-PK1 cells Toxicology and Applied Pharmacology. 114: 9-15. PMID 1585377 DOI: 10.1016/0041-008X(92)90090-F  1
1992 Merrill AH. Vitamin E supplementation enhances immune response in the elderly Nutrition Reviews. 50: 85-87. PMID 1565294  1
1992 Merrill AH. Sweet foods and calorie consumption at meals Nutrition Reviews. 50: 83-85. PMID 1565293  1
1992 Merrill AH. Is putrescine an essential nutrient for avians? Nutrition Reviews. 50: 81-83. PMID 1565292  1
1992 Merrill AH. Estimating body fat in lean and obese women Nutrition Reviews. 50: 80-81. PMID 1565291  1
1992 Merrill AH. Ceramide: A new lipid 'second messenger'? Nutrition Reviews. 50: 78-87. PMID 1565290 DOI: 10.1111/j.1753-4887.1992.tb01273.x  1
1992 Enkvetchakul B, Barnett T, Liotta DC, Geisler V, Menaldino D, Merrill AH, Birt DF. Influences of sphingosine on two-stage skin tumorigenesis in Sencar mice. Cancer Letters. 62: 35-42. PMID 1540929 DOI: 10.1016/0304-3835(92)90195-2  1
1992 Merrill AH, Wang E, LaRocque R, Mullins RE, Morgan ET, Hargrove JL, Bonkovsky HL, Popova IA. Differences in glycogen, lipids, and enzymes in livers from rats flown on COSMOS 2044 Journal of Applied Physiology. 73. PMID 1526942  1
1992 Merrill AH, Wang E, Mullins RE, Grindeland RE, Popova IA. Analyses of plasma for metabolic and hormonal changes in rats flown aboard COSMOS 2044 Journal of Applied Physiology. 73. PMID 1526939  1
1992 Norred WP, Wang E, Yoo H, Riley RT, Merrill AH. In vitro toxicology of fumonisins and the mechanistic implications Mycopathologia. 117: 73-78. PMID 1513375 DOI: 10.1007/BF00497281  1
1992 Merrill AH, Wang E. Enzymes of ceramide biosynthesis Methods in Enzymology. 209: 427-437. PMID 1495423 DOI: 10.1016/0076-6879(92)09053-6  1
1991 Merrill AH. Cell regulation by sphingosine and more complex sphingolipids Journal of Bioenergetics and Biomembranes. 23: 83-104. PMID 2010436 DOI: 10.1007/BF00768840  1
1991 Borek C, Ong A, Stevens VL, Wang E, Merrill AH. Long-chain (sphingoid) bases inhibit multistage carcinogenesis in mouse C3H/10T1/2 cells treated with radiation and phorbol 12-myristate 13-acetate. Proceedings of the National Academy of Sciences of the United States of America. 88: 1953-7. PMID 2000399  1
1991 Hannun YA, Merrill AH, Bell RM. Use of sphingosine as inhibitor of protein kinase C Methods in Enzymology. 201: 316-328. PMID 1943771 DOI: 10.1016/0076-6879(91)01028-Z  1
1991 Wang E, Norred WP, Bacon CW, Riley RT, Merrill AH. Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme Journal of Biological Chemistry. 266: 14486-14490. PMID 1860857  1
1991 Uhlinger DJ, Burnham DN, Mullins RE, Kalmar JR, Cutler CW, Arnold RR, Lambeth JD, Merrill AH. Functional differences in human neutrophils isolated pre- and post-prandially. Febs Letters. 286: 28-32. PMID 1650714 DOI: 10.1016/0014-5793(91)80933-T  1
1991 Merrill AH, Liotta DC. Lipids as hormones and second messengers Current Opinion in Structural Biology. 1: 516-521. DOI: 10.1016/S0959-440X(05)80071-5  1
1990 Stevens VL, Nimkar S, Jamison WC, Liotta DC, Merrill AH. Characteristics of the growth inhibition and cytotoxicity of long-chain (sphingoid) bases for Chinese hamster ovary cells: evidence for an involvement of protein kinase C. Biochimica Et Biophysica Acta. 1051: 37-45. PMID 2297538 DOI: 10.1016/0167-4889(90)90171-9  1
1990 Merrill AH, Henderson JM. Vitamin B6 metabolism by human liver Annals of the New York Academy of Sciences. 585: 110-117. PMID 2192606  1
1990 Merrill AH, Jones DD. An update of the enzymology and regulation of sphingomyelin metabolism. Biochimica Et Biophysica Acta. 1044: 1-12. PMID 2187537 DOI: 10.1016/0005-2760(90)90211-F  1
1990 Yamada Y, Merrill AH, McCormick DB. Probable reaction mechanisms of flavokinase and FAD synthetase from rat liver Archives of Biochemistry and Biophysics. 278: 125-130. PMID 2157358 DOI: 10.1016/0003-9861(90)90240-Y  1
1990 Stevens VL, Owens NE, Kinkade JM, Merrill AH, Winton EF. Modulation of Retinoic Acid-induced Differentiation of Human Leukemia (HL-60) Cells by Serum Factors and Sphinganine Cancer Research. 50: 222-226. PMID 2153047  1
1990 Greenberg P, Merrill AH, Liotta DC, Grabowski GA. Human acid beta-glucosidase: use of sphingosyl and N-alkyl-glucosylamine inhibitors to investigate the properties of the active site. Biochimica Et Biophysica Acta. 1039: 12-20. PMID 2141287 DOI: 10.1016/0167-4838(90)90220-A  1
1989 Henderson JM, Scott SS, Merrill AH, Hollins B, Kutner MH. Vitamin B6 repletion in cirrhosis with oral pyridoxine: Failure to improve amino acid metabolism Hepatology. 9: 582-588. PMID 2925164 DOI: 10.1002/hep.1840090412  1
1989 Enkvetchakul B, Merrill AH, Birt DF. Inhibition of the induction of ornithine decarboxylase activity by 12-o-tetradecanoylphorbol-13-acetate in mouse skin by sphingosine sulfate Carcinogenesis. 10: 379-381. PMID 2912589 DOI: 10.1093/carcin/10.2.379  1
1989 Merrill AH, Nimkar S, Menaldino D, Hannun YA, Loomis C, Bell RM, Tyagi SR, Lambeth JD, Stevens VL, Hunter R, Liotta DC. Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds Biochemistry. 28: 3138-3145. PMID 2742830 DOI: 10.1021/bi00434a004  1
1989 Stevens VL, Owens NE, Kinkade JM, Merrill AH, Smith EE, Winton EF. Differential Effects of Long-Chain (Sphingoid) Bases on the Monocytic Differentiation of Human Leukemia (HL-60) Cells Induced by Phorbol Esters, l±l,25-Dihydroxyvitamin D3, or Ganglioside Gm3 Cancer Research. 49: 3229-3234. PMID 2720676  1
1989 Robertson DG, DiGirolamo M, Merrill AH, Lambeth JD. Insulin-stimulated hexose transport and glucose oxidation in rat adipocytes is inhibited by sphingosine at a step after insulin binding Journal of Biological Chemistry. 264: 6773-6779. PMID 2651433  1
1989 Merrill AH, Stevens VL. Modulation of protein kinase C and diverse cell functions by sphingosine - a pharmacologically interesting compound linking sphingolipids and signal transduction Bba - Molecular Cell Research. 1010: 131-139. PMID 2643437 DOI: 10.1016/0167-4889(89)90152-3  1
1989 Messmer TO, Wang E, Stevens VL, Merrill AH. Sphingolipid biosynthesis by rat liver cells: Effects of serine, fatty acids and lipoproteins Journal of Nutrition. 119: 534-538. PMID 2495341  1
1988 Merrill AH, Wang E, Mullins RE, Jamison WC, Nimkar S, Liotta DC. Quantitation of free sphingosine in liver by high-performance liquid chromatography. Analytical Biochemistry. 171: 373-81. PMID 3407935 DOI: 10.1016/0003-2697(88)90500-3  1
1988 Medlock KA, Merrill AH. Inhibition of serine palmitoyltransferase in vitro and long-chain base biosynthesis in intact Chinese hamster ovary cells by β-chloroalanine Biochemistry. 27: 7079-7084. PMID 3143407  1
1988 Medlock KA, Merrill AH. Rapid turnover of sphingosine synthesized de novo from [14C]serine by Chinese hamster ovary cells Biochemical and Biophysical Research Communications. 157: 232-237. PMID 3143361 DOI: 10.1016/S0006-291X(88)80037-8  1
1988 Merrill AH, Wang E, Mullins RE. Kinetics of long-chain (sphingoid) base biosynthesis in intact LM cells: Effects of varying the extracellular concentrations of serine and fatty acid precursors of this pathway Biochemistry. 27: 340-345. PMID 3126810  1
1988 Nimkar S, Menaldino D, Merrill AH, Liotta D. A stereoselective synthesis of sphingosine, a protein kinase c inhibitor Tetrahedron Letters. 29: 3037-3040. DOI: 10.1016/0040-4039(88)85079-2  1
1987 Merrill AH, Wang E, Jones DP, Hargrove JL. Hepatic function in rats after spaceflight: Effects on lipids, glycogen, and enzymes American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 252. PMID 3812760  1
1987 Merrill AH, Henderson JM. Diseases associated with defects in vitamin B6 metabolism or utilization Annual Review of Nutrition. 7: 137-156. PMID 3300730  1
1986 Innis WS, Nixon DW, Murray DR, McCormick DB, Merrill AH. Immunoglobulins associated with elevated riboflavin binding by plasma from cancer patients. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 181: 237-41. PMID 3945631 DOI: 10.3181/00379727-181-42247  1
1986 Merrill AH, Wang E, Wertz PW. Differences in the long chain (sphingoid) base composition of sphingomyelin from rats bearing Morris hepatoma 7777 Lipids. 21: 529-530. PMID 3762323 DOI: 10.1007/BF02535642  1
1986 Henderson JM, Codner MA, Hollins B, Kutner MH, Merrill AH. The fasting B6 vitamer profile and response to a pyridoxine load in normal and cirrhotic subjects Hepatology. 6: 464-471. PMID 3710434 DOI: 10.1002/hep.1840060324  1
1986 Merrill AH, Sereni AM, Stevens VL, Hannun YA, Bell RM, Kinkade JM. Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases Journal of Biological Chemistry. 261: 12610-12615. PMID 3462189  1
1986 Hannun YA, Loomis CR, Merrill AH, Bell RM. Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets Journal of Biological Chemistry. 261: 12604-12609. PMID 3462188  1
1986 Merrill AH, Wang E. Biosynthesis of long-chain (sphingoid) bases from serine by LM cells. Evidence for introduction of the 4-trans-double bond after de novo biosynthesis of N-acylsphinganine(s) Journal of Biological Chemistry. 261: 3764-3769. PMID 3081509  1
1986 Merrill AH, Henderson JM, Wang E, Codner MA, Hollins B, Millikan WJ. Activities of the hepatic enzymes of vitamin B6 metabolism for patients with cirrhosis American Journal of Clinical Nutrition. 44: 461-467. PMID 3020959  1
1986 Wilson E, Olcott MC, Bell RM, Merrill AH, Lambeth JD. Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst Journal of Biological Chemistry. 261: 12616-12623. PMID 3017982  1
1986 Merrill AH, Wang E. Highly sensitive methods for assaying the enzymes of vitamin B6 metabolism Methods in Enzymology. 110-116. PMID 3010031  1
1986 Merrill AH, Wang E, Yanish M, Nixon DW. Effects of human plasma on lipid metabolism by 3T3-L1 cells Nutrition Research. 6: 923-929. DOI: 10.1016/S0271-5317(86)80067-7  1
1985 Innis WSA, McCormick DB, Merrill AH. Variations in riboflavin binding by human plasma: Identification of immunoglobulins as the major proteins responsible Biochemical Medicine. 34: 151-165. PMID 4084240 DOI: 10.1016/0006-2944(85)90106-1  1
1985 Merrill AH, Nixon DW, Williams RD. Activities of serine palmitoyltransferase (3-ketosphinganine synthase) in microsomes from different rat tissues Journal of Lipid Research. 26: 617-622. PMID 4020300  1
1985 Merrill AH, Wang E, Innis WSA, Mullins R. Increases in serum sphingomyelin by 17β-estradiol Lipids. 20: 252-254. PMID 3999932 DOI: 10.1007/BF02534197  1
1985 Merrill AH, Wang E, Hargrove JL. Hepatic enzymes of sphingolipid and glycerolipid biosynthesis in rats from Spacelab 3 The Physiologist. 28. PMID 3834473  1
1985 Merrill AH, Wang E. Biosynthesis of long-chain (sphingoid) bases by LM cells Federation Proceedings. 44.  1
1984 Nixon DW, Williams RD, Merrill AH. Comparison of Serine Palmitoyltransferase in Morris Hepatoma 7777 and Rat Liver Cancer Research. 44: 1918-1923. PMID 6713393  1
1984 Merrill AH, Wang E, Stevens J, Brumley GW. Activities of the initial enzymes of glycerolipid and sphingolipid synthesis in lung microsomes from rats exposed to air or 85% oxygen Biochemical and Biophysical Research Communications. 119: 995-1000. PMID 6712682 DOI: 10.1016/0006-291X(84)90872-6  1
1984 Merrill AH, Williams RD. Utilization of different fatty acyl-CoA thioesters by serine palmitoyltransferase from rat brain Journal of Lipid Research. 25: 185-188. PMID 6707526  1
1984 Williams RD, Wang E, Merrill AH. Enzymology of long-chain base synthesis by liver: Characterization of serine palmitoyltransferase in rat liver microsomes Archives of Biochemistry and Biophysics. 228: 282-291. PMID 6421234 DOI: 10.1016/0003-9861(84)90069-9  1
1984 Merrill AH, Henderson JM, Wang E, McDonald BW, Millikan WJ. Metabolism of vitamin B-6 by human liver Journal of Nutrition. 114: 1664-1674. PMID 6088736  1
1984 Innis WSA, Merrill AH, McCormick DB. Analyses of ribolavin binding by human plasma proteins Federation Proceedings. 43.  1
1983 Merrill AH. Characterization of serine palmitoyltransferase activity in Chinese hamster ovary cells Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 754: 284-291. PMID 6652105 DOI: 10.1016/0005-2760(83)90144-3  1
1982 Merrill AH, Gidwitz S, Bell RM. Facile enzymatic synthesis of fatty acylcoenzyme A thioesters Journal of Lipid Research. 23: 1368-1373. PMID 7161565  1
1981 Green PR, Merrill AH, Bell RM. Membrane phospholipid synthesis in Escherichia coli. Purification, reconstitution, and characterization of sn-glycerol-3-phosphate acyltransferase Journal of Biological Chemistry. 256: 11151-11159. PMID 7026564  1
1981 Merrill AH, Froehlich JA, McCormick DB. Isolation and identification of alternative riboflavin-binding proteins from human plasma Biochemical Medicine. 25: 198-206. PMID 6793039 DOI: 10.1016/0006-2944(81)90076-4  1
1981 Merrill AH, Lambeth JD, Edmondson DE, McCormick DB. Formation and mode of action of flavoproteins Annual Review of Nutrition. 1: 281-317. PMID 6764718  1
1980 Merrill AH, Korytnyk W, Horiike K, McCormick DB. Spectroscopic studies of complexes between pyridoxamine (pyridoxine)-5′-phosphate oxidase and pyridoxyl 5′-phosphate compounds differing at position 4′ Bba - Protein Structure. 626: 57-63. PMID 7459383 DOI: 10.1016/0005-2795(80)90196-8  1
1980 Merrill AH, McCormick DB. Affinity chromatographic purification and properties of flavokinase (ATP:riboflavin 5'-phosphotransferase) from rat liver Journal of Biological Chemistry. 255: 1335-1338. PMID 6243635  1
1980 Froehlich JA, Merrill AH, Clagett CO, McCormick DB. Affinity chromatographic purification and comparison of riboflavin-binding proteins from laying hen liver and blood and from egg yolk Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 66: 397-401. DOI: 10.1016/0305-0491(80)90223-0  1
1980 Merrill AH, McCormick DB. [48] Flavin affinity chromatography Methods in Enzymology. 66: 338-344. DOI: 10.1016/0076-6879(80)66478-7  1
1980 MERRILL AH, McCormick DB. [40] Preparation of flavin 5′-phosphates using immobilized flavokinase Methods in Enzymology. 66: 287-290. DOI: 10.1016/0076-6879(80)66470-2  1
1979 Merrill AH, Froehlich JA, McCormick DB. Purification of riboflavin-binding proteins from bovine plasma and discovery of a pregnancy-specific riboflavin-binding protein Journal of Biological Chemistry. 254: 9362-9364. PMID 489537  1
1979 Merrill AH. Spectroscopic studies of pyridoxamine (Pyridoxine) 5′-phosphate oxidase. Equilibrium dissociation constants and spectra for riboflavin 5′-phosphate and analogues Biochemistry. 18: 3635-3641. PMID 476073  1
1979 Horiike K, Merrill AH, McCormick DB. Activation and inactivation of rabbit liver pyridoxamine (pyridoxine) 5′-phosphate oxidase activity by urea and other solutes Archives of Biochemistry and Biophysics. 195: 325-335. PMID 475395 DOI: 10.1016/0003-9861(79)90358-8  1
1979 Colin Campbell T, Hayes JR, Merrill AH, Maso M, Goetchius M. The influence of dietary factors on drug metabolism in animals Drug Metabolism Reviews. 9: 173-184. PMID 385269 DOI: 10.3109/03602537908993889  1
1979 Merrill AH, McCormick DB. Preparation and properties of immobilized flavokinase Biotechnology and Bioengineering. 21: 1629-1638. PMID 227492 DOI: 10.1002/bit.260210909  1
1979 Merrill AH, Kazarinoff MN, Tsuge H, Horiike K, McCormick DB. [83] Pyridoxamine (pyridoxine) 5′-phosphate oxidase from rabbit liver Methods in Enzymology. 62: 568-574. DOI: 10.1016/0076-6879(79)62263-2  1
1978 Hayes JR, Mgbodile MUK, Merrill AH, Nerurkar LS, Campbell TC. The effect of dietary protein depletion and repletion on rat hepatic mixed function oxidase activities Journal of Nutrition. 108: 1788-1797. PMID 712423  1
1978 Merrill AH, Horiike K, McCormick DB. Evidence for the regulation of pyridoxal 5′-phosphate formation in liver by pyridoxamine (pyridoxine) 5′-phosphate oxidase Biochemical and Biophysical Research Communications. 83: 984-990. PMID 708447 DOI: 10.1016/0006-291X(78)91492-4  1
1978 Merrill AH, McCormick DB. Flavin affinity chromatography: General methods for purification of proteins that bind riboflavin Analytical Biochemistry. 89: 87-102. PMID 212963 DOI: 10.1016/0003-2697(78)90729-7  1
1978 Merrill AH, Addison R, McCormick DB. Induction of Hepatic and Intestinal Flavokinase After Oral Administration of Riboflavin to Riboflavin-Deficient Rats (40248) Proceedings of the Society For Experimental Biology and Medicine. 158: 572-574. PMID 211518 DOI: 10.3181/00379727-158-40248  1
1974 Merrill AH, Campbell TC. Preliminary study of in vitro aflatoxin B1 metabolism by human liver Toxicology and Applied Pharmacology. 27: 210-213. PMID 4853735 DOI: 10.1016/0041-008X(74)90190-2  1
1974 Merrill AH, Salamat L, Campbell TC. Studies on the excretion of aflatoxin and its derivatives by humans Toxicology and Applied Pharmacology. 29.  1
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