Lloyd D. Fricker - Publications

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
Neuroscience Biology, Pharmacology, Biochemistry

164 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Garcia-Pardo J, Tanco S, Garcia-Guerrero MC, Dasgupta S, Avilés FX, Lorenzo J, Fricker LD. Substrate Specificity and Structural Modeling of Human Carboxypeptidase Z: A Unique Protease with a Frizzled-Like Domain. International Journal of Molecular Sciences. 21. PMID 33217972 DOI: 10.3390/ijms21228687  0.6
2019 Dasgupta S, Fishman MA, Castro LM, Tashima AK, Ferro ES, Fricker LD. Effect of Protein Denaturation and Enzyme Inhibitors on Proteasomal-Mediated Production of Peptides in Human Embryonic Kidney Cells. Biomolecules. 9. PMID 31142026 DOI: 10.3390/biom9060207  0.6
2017 Garcia-Pardo J, Tanco S, Díaz L, Dasgupta S, Fernandez-Recio J, Lorenzo J, Aviles FX, Fricker LD. Substrate specificity of human metallocarboxypeptidase D: Comparison of the two active carboxypeptidase domains. Plos One. 12: e0187778. PMID 29131831 DOI: 10.1371/journal.pone.0187778  0.6
2017 Berezniuk I, Rodriguiz RM, Zee ML, Marcus DJ, Pintar J, Morgan DJ, Wetsel WC, Fricker LD. ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine. Journal of Neurochemistry. PMID 28881029 DOI: 10.1111/jnc.14209  1
2016 Dasgupta S, Yang C, Castro LM, Tashima AK, Ferro ES, Moir RD, Willis IM, Fricker LD. Analysis of the Yeast Peptidome and Comparison with the Human Peptidome. Plos One. 11: e0163312. PMID 27685651 DOI: 10.1371/journal.pone.0163312  0.6
2016 Gomes I, Bobeck EN, Margolis EB, Gupta A, Sierra S, Fakira AK, Fujita W, Müller TD, Müller A, Tschöp MH, Kleinau G, Fricker LD, Devi LA. Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Science Signaling. 9: ra43. PMID 27117253 DOI: 10.1126/scisignal.aad0694  1
2016 Lopes MW, Sapio MR, Leal RB, Fricker LD. Knockdown of Carboxypeptidase A6 in Zebrafish Larvae Reduces Response to Seizure-Inducing Drugs and Causes Changes in the Level of mRNAs Encoding Signaling Molecules. Plos One. 11: e0152905. PMID 27050163 DOI: 10.1371/journal.pone.0152905  1
2015 Dasgupta S, Fishman MA, Mahallati H, Castro LM, Tashima AK, Ferro ES, Fricker LD. Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington's Disease. Plos One. 10: e0145333. PMID 26691307 DOI: 10.1371/journal.pone.0145333  1
2015 Fricker LD. Limitations of Mass Spectrometry-Based Peptidomic Approaches. Journal of the American Society For Mass Spectrometry. 26: 1981-91. PMID 26305799 DOI: 10.1007/s13361-015-1231-x  1
2015 Sapio MR, Vessaz M, Thomas P, Genton P, Fricker LD, Salzmann A. Novel carboxypeptidase A6 (CPA6) mutations identified in patients with juvenile myoclonic and generalized epilepsy. Plos One. 10: e0123180. PMID 25875328 DOI: 10.1371/journal.pone.0123180  1
2014 Wardman JH, Fricker LD. ProSAAS-derived peptides are differentially processed and sorted in mouse brain and AtT-20 cells. Plos One. 9: e104232. PMID 25148519 DOI: 10.1371/journal.pone.0104232  1
2014 Dasgupta S, Castro LM, Dulman R, Yang C, Schmidt M, Ferro ES, Fricker LD. Proteasome inhibitors alter levels of intracellular peptides in HEK293T and SH-SY5Y cells. Plos One. 9: e103604. PMID 25079948 DOI: 10.1371/journal.pone.0103604  1
2014 Sapio MR, Fricker LD. Carboxypeptidases in disease: insights from peptidomic studies. Proteomics. Clinical Applications. 8: 327-37. PMID 24470285 DOI: 10.1002/prca.201300090  1
2014 Schrader M, Schulz-Knappe P, Fricker LD. Historical perspective of peptidomics Eupa Open Proteomics. 3: 171-182. DOI: 10.1016/j.euprot.2014.02.014  1
2014 Ferro ES, Rioli V, Castro LM, Fricker LD. Intracellular peptides: From discovery to function Eupa Open Proteomics. 3: 143-151. DOI: 10.1016/j.euprot.2014.02.009  1
2014 Dasgupta S, Fricker LD. High-Resolution Analytical Tools for Quantitative Peptidomics Comprehensive Analytical Chemistry. 63: 305-324. DOI: 10.1016/B978-0-444-62651-6.00014-3  1
2013 Gomes I, Aryal DK, Wardman JH, Gupta A, Gagnidze K, Rodriguiz RM, Kumar S, Wetsel WC, Pintar JE, Fricker LD, Devi LA. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proceedings of the National Academy of Sciences of the United States of America. 110: 16211-6. PMID 24043826 DOI: 10.1073/pnas.1312938110  1
2013 Lyons PJ, Sapio MR, Fricker LD. Zebrafish cytosolic carboxypeptidases 1 and 5 are essential for embryonic development. The Journal of Biological Chemistry. 288: 30454-62. PMID 24022483 DOI: 10.1074/jbc.M113.497933  1
2013 Berezniuk I, Lyons PJ, Sironi JJ, Xiao H, Setou M, Angeletti RH, Ikegami K, Fricker LD. Cytosolic carboxypeptidase 5 removes α- and γ-linked glutamates from tubulin. The Journal of Biological Chemistry. 288: 30445-53. PMID 24022482 DOI: 10.1074/jbc.M113.497917  1
2013 Berezniuk I, Sironi JJ, Wardman J, Pasek RC, Berbari NF, Yoder BK, Fricker LD. Quantitative peptidomics of Purkinje cell degeneration mice. Plos One. 8: e60981. PMID 23593366 DOI: 10.1371/journal.pone.0060981  1
2013 Rodriguiz RM, Wilkins JJ, Creson TK, Biswas R, Berezniuk I, Fricker AD, Fricker LD, Wetsel WC. Emergence of anxiety-like behaviours in depressive-like Cpe(fat/fat) mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1623-34. PMID 23442571 DOI: 10.1017/S1461145713000059  1
2013 Gelman JS, Dasgupta S, Berezniuk I, Fricker LD. Analysis of peptides secreted from cultured mouse brain tissue. Biochimica Et Biophysica Acta. 1834: 2408-17. PMID 23402728 DOI: 10.1016/j.bbapap.2013.01.043  1
2013 Gelman JS, Sironi J, Berezniuk I, Dasgupta S, Castro LM, Gozzo FC, Ferro ES, Fricker LD. Alterations of the intracellular peptidome in response to the proteasome inhibitor bortezomib. Plos One. 8: e53263. PMID 23308178 DOI: 10.1371/journal.pone.0053263  1
2013 Wardman JH, Fricker LD. Peptidomics of Mice Lacking Peptide Processing Enzymes Handbook of Biologically Active Peptides. 1765-1771. DOI: 10.1016/B978-0-12-385095-9.00242-6  1
2013 Fricker LD. Carboxypeptidases E and D Handbook of Biologically Active Peptides. 1715-1720. DOI: 10.1016/B978-0-12-385095-9.00235-9  1
2013 Fricker LD. Carboxypeptidase A5 Handbook of Proteolytic Enzymes. 1: 1315-1317. DOI: 10.1016/B978-0-12-382219-2.00294-5  1
2013 Fricker LD, Gomis-Rüth FX. Carboxypeptidase A4 Handbook of Proteolytic Enzymes. 1: 1307-1310. DOI: 10.1016/B978-0-12-382219-2.00292-1  1
2013 Devi LA, Fricker LD. Transmitter and peptide receptors: Basic principles Neuroscience in the 21st Century: From Basic to Clinical. 1505-1523. DOI: 10.1007/978-1-4614-1997-6_52  1
2013 Devi LA, Fricker LD. Transmitters and peptides: Basic principles Neuroscience in the 21st Century: From Basic to Clinical. 1487-1503. DOI: 10.1007/978-1-4614-1997-6_51  1
2012 Sapio MR, Salzmann A, Vessaz M, Crespel A, Lyons PJ, Malafosse A, Fricker LD. Naturally occurring carboxypeptidase A6 mutations: effect on enzyme function and association with epilepsy. The Journal of Biological Chemistry. 287: 42900-9. PMID 23105115 DOI: 10.1074/jbc.M112.414094  1
2012 Fricker LD. Mass spectrometry of immunolabeled neurons--the best of both techniques. Chemistry & Biology. 19: 931-2. PMID 22921059 DOI: 10.1016/j.chembiol.2012.08.003  1
2012 Fricker LD, Gelman JS, Castro LM, Gozzo FC, Ferro ES. Peptidomic analysis of HEK293T cells: effect of the proteasome inhibitor epoxomicin on intracellular peptides. Journal of Proteome Research. 11: 1981-90. PMID 22304392 DOI: 10.1021/pr2012076  1
2012 Gelman JS, Wardman J, Bhat VB, Gozzo FC, Fricker LD. Quantitative peptidomics to measure neuropeptide levels in animal models relevant to psychiatric disorders. Methods in Molecular Biology (Clifton, N.J.). 829: 487-503. PMID 22231834 DOI: 10.1007/978-1-61779-458-2_31  1
2012 Berezniuk I, Vu HT, Lyons PJ, Sironi JJ, Xiao H, Burd B, Setou M, Angeletti RH, Ikegami K, Fricker LD. Cytosolic carboxypeptidase 1 is involved in processing α- and β-tubulin. The Journal of Biological Chemistry. 287: 6503-17. PMID 22170066 DOI: 10.1074/jbc.M111.309138  1
2012 Salzmann A, Guipponi M, Lyons PJ, Fricker LD, Sapio M, Lambercy C, Buresi C, Ouled Amar Bencheikh B, Lahjouji F, Ouazzani R, Crespel A, Chaigne D, Malafosse A. Carboxypeptidase A6 gene (CPA6) mutations in a recessive familial form of febrile seizures and temporal lobe epilepsy and in sporadic temporal lobe epilepsy. Human Mutation. 33: 124-35. PMID 21922598 DOI: 10.1002/humu.21613  1
2011 Wardman JH, Berezniuk I, Di S, Tasker JG, Fricker LD. ProSAAS-derived peptides are colocalized with neuropeptide Y and function as neuropeptides in the regulation of food intake. Plos One. 6: e28152. PMID 22164236 DOI: 10.1371/journal.pone.0028152  1
2011 Lyons PJ, Fricker LD. Carboxypeptidase O is a glycosylphosphatidylinositol-anchored intestinal peptidase with acidic amino acid specificity. The Journal of Biological Chemistry. 286: 39023-32. PMID 21921028 DOI: 10.1074/jbc.M111.265819  1
2011 Lyons PJ, Fricker LD. Peptidomic approaches to study proteolytic activity. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit18.13. PMID 21842468 DOI: 10.1002/0471140864.ps1813s65  1
2011 Wardman J, Fricker LD. Quantitative peptidomics of mice lacking peptide-processing enzymes. Methods in Molecular Biology (Clifton, N.J.). 768: 307-23. PMID 21805251 DOI: 10.1007/978-1-61779-204-5_17  1
2011 Helwig M, Vivoli M, Fricker LD, Lindberg I. Regulation of neuropeptide processing enzymes by catecholamines in endocrine cells. Molecular Pharmacology. 80: 304-13. PMID 21540292 DOI: 10.1124/mol.111.072090  1
2011 Gelman JS, Sironi J, Castro LM, Ferro ES, Fricker LD. Peptidomic analysis of human cell lines. Journal of Proteome Research. 10: 1583-92. PMID 21204522 DOI: 10.1021/pr100952f  1
2010 Lyons PJ, Ma LH, Baker R, Fricker LD. Carboxypeptidase A6 in zebrafish development and implications for VIth cranial nerve pathfinding. Plos One. 5: e12967. PMID 20885977 DOI: 10.1371/journal.pone.0012967  1
2010 Lyons PJ, Fricker LD. Substrate specificity of human carboxypeptidase A6. The Journal of Biological Chemistry. 285: 38234-42. PMID 20855895 DOI: 10.1074/jbc.M110.158626  1
2010 Berezniuk I, Fricker LD. A defect in cytosolic carboxypeptidase 1 (Nna1) causes autophagy in Purkinje cell degeneration mouse brain. Autophagy. 6: 558-9. PMID 20484972 DOI: 10.4161/auto.6.4.11813  1
2010 Fricker LD. Analysis of mouse brain peptides using mass spectrometry-based peptidomics: implications for novel functions ranging from non-classical neuropeptides to microproteins. Molecular Biosystems. 6: 1355-65. PMID 20428524 DOI: 10.1039/c003317k  1
2010 Wardman JH, Zhang X, Gagnon S, Castro LM, Zhu X, Steiner DF, Day R, Fricker LD. Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics. Journal of Neurochemistry. 114: 215-25. PMID 20412386 DOI: 10.1111/j.1471-4159.2010.06760.x  1
2010 Sidyelyeva G, Wegener C, Schoenfeld BP, Bell AJ, Baker NE, McBride SMJ, Fricker LD. Individual carboxypeptidase D domains have both redundant and unique functions in Drosophila development and behavior Cellular and Molecular Life Sciences. 67: 2991-3004. PMID 20386952 DOI: 10.1007/s00018-010-0369-8  1
2010 Tanco S, Zhang X, Morano C, Avilés FX, Lorenzo J, Fricker LD. Characterization of the substrate specificity of human carboxypeptidase A4 and implications for a role in extracellular peptide processing. The Journal of Biological Chemistry. 285: 18385-96. PMID 20385563 DOI: 10.1074/jbc.M109.060350  1
2010 Gelman JS, Fricker LD. Hemopressin and other bioactive peptides from cytosolic proteins: are these non-classical neuropeptides? The Aaps Journal. 12: 279-89. PMID 20383670 DOI: 10.1208/s12248-010-9186-0  1
2010 Morgan DJ, Wei S, Gomes I, Czyzyk T, Mzhavia N, Pan H, Devi LA, Fricker LD, Pintar JE. The propeptide precursor proSAAS is involved in fetal neuropeptide processing and body weight regulation. Journal of Neurochemistry. 113: 1275-84. PMID 20367757 DOI: 10.1111/j.1471-4159.2010.06706.x  1
2010 Gelman JS, Sironi J, Castro LM, Ferro ES, Fricker LD. Hemopressins and other hemoglobin-derived peptides in mouse brain: comparison between brain, blood, and heart peptidome and regulation in Cpefat/fat mice. Journal of Neurochemistry. 113: 871-80. PMID 20202081 DOI: 10.1111/j.1471-4159.2010.06653.x  1
2010 Berezniuk I, Sironi J, Callaway MB, Castro LM, Hirata IY, Ferro ES, Fricker LD. CCP1/Nna1 functions in protein turnover in mouse brain: Implications for cell death in Purkinje cell degeneration mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1813-23. PMID 20061535 DOI: 10.1096/fj.09-147942  1
2010 Zhang X, Pan H, Peng B, Steiner DF, Pintar JE, Fricker LD. Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis. Journal of Neurochemistry. 112: 1168-79. PMID 19968759 DOI: 10.1111/j.1471-4159.2009.06530.x  1
2009 Gomes I, Grushko JS, Golebiewska U, Hoogendoorn S, Gupta A, Heimann AS, Ferro ES, Scarlata S, Fricker LD, Devi LA. Novel endogenous peptide agonists of cannabinoid receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3020-9. PMID 19380512 DOI: 10.1096/fj.09-132142  1
2009 Berti DA, Morano C, Russo LC, Castro LM, Cunha FM, Zhang X, Sironi J, Klitzke CF, Ferro ES, Fricker LD. Analysis of intracellular substrates and products of thimet oligopeptidase in human embryonic kidney 293 cells. The Journal of Biological Chemistry. 284: 14105-16. PMID 19282285 DOI: 10.1074/jbc.M807916200  1
2008 Morano C, Zhang X, Fricker LD. Multiple isotopic labels for quantitative mass spectrometry. Analytical Chemistry. 80: 9298-309. PMID 19551992 DOI: 10.1021/ac801654h  1
2008 Zhang X, Che FY, Berezniuk I, Sonmez K, Toll L, Fricker LD. Peptidomics of Cpe(fat/fat) mouse brain regions: implications for neuropeptide processing. Journal of Neurochemistry. 107: 1596-613. PMID 19014391 DOI: 10.1111/j.1471-4159.2008.05722.x  1
2008 Lyons PJ, Callaway MB, Fricker LD. Characterization of carboxypeptidase A6, an extracellular matrix peptidase. The Journal of Biological Chemistry. 283: 7054-63. PMID 18178555 DOI: 10.1074/jbc.M707680200  1
2007 Che FY, Zhang X, Berezniuk I, Callaway M, Lim J, Fricker LD. Optimization of neuropeptide extraction from the mouse hypothalamus. Journal of Proteome Research. 6: 4667-76. PMID 17979226 DOI: 10.1021/pr060690r  1
2007 Fricker LD. Neuropeptidomics to study peptide processing in animal models of obesity. Endocrinology. 148: 4185-90. PMID 17584973 DOI: 10.1210/en.2007-0123  1
2007 Arolas JL, Vendrell J, Aviles FX, Fricker LD. Metallocarboxypeptidases: emerging drug targets in biomedicine. Current Pharmaceutical Design. 13: 349-66. PMID 17311554 DOI: 10.2174/138161207780162980  1
2007 Kalinina E, Biswas R, Berezniuk I, Hermoso A, Aviles FX, Fricker LD. A novel subfamily of mouse cytosolic carboxypeptidases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 836-50. PMID 17244818 DOI: 10.1096/fj.06-7329com  1
2007 Rodriguez de la Vega M, Sevilla RG, Hermoso A, Lorenzo J, Tanco S, Diez A, Fricker LD, Bautista JM, Avilés FX. Nna1-like proteins are active metallocarboxypeptidases of a new and diverse M14 subfamily. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 851-65. PMID 17244817 DOI: 10.1096/fj.06-7330com  1
2006 Pan H, Che FY, Peng B, Steiner DF, Pintar JE, Fricker LD. The role of prohormone convertase-2 in hypothalamic neuropeptide processing: a quantitative neuropeptidomic study. Journal of Neurochemistry. 98: 1763-77. PMID 16903874 DOI: 10.1111/j.1471-4159.2006.04067.x  1
2006 Décaillot FM, Che FY, Fricker LD, Devi LA. Peptidomics of Cpefat/fat mouse hypothalamus and striatum: effect of chronic morphine administration. Journal of Molecular Neuroscience : Mn. 28: 277-84. PMID 16691015 DOI: 10.1385/JMN:28:3:277  1
2006 Che FY, Vathy I, Fricker LD. Quantitative peptidomics in mice: effect of cocaine treatment. Journal of Molecular Neuroscience : Mn. 28: 265-75. PMID 16691014 DOI: 10.1385/JMN:28:3:265  1
2006 Kalinina E, Fontenele-Neto JD, Fricker LD. Drosophila S2 cells produce multiple forms of carboxypeptidase D with different intracellular distributions. Journal of Cellular Biochemistry. 99: 770-83. PMID 16676361 DOI: 10.1002/jcb.20972  1
2006 Sidyelyeva G, Baker NE, Fricker LD. Characterization of the molecular basis of the Drosophila mutations in carboxypeptidase D: Effect on enzyme activity and expression Journal of Biological Chemistry. 281: 13844-13852. PMID 16556608 DOI: 10.1074/jbc.M513499200  1
2006 Lim J, Berezniuk I, Che FY, Parikh R, Biswas R, Pan H, Fricker LD. Altered neuropeptide processing in prefrontal cortex of Cpe (fat/fat) mice: implications for neuropeptide discovery. Journal of Neurochemistry. 96: 1169-81. PMID 16417576 DOI: 10.1111/j.1471-4159.2005.03614.x  1
2006 Fricker LD, Lim J, Pan H, Che FY. Peptidomics: identification and quantification of endogenous peptides in neuroendocrine tissues. Mass Spectrometry Reviews. 25: 327-44. PMID 16404746 DOI: 10.1002/mas.20079  1
2005 Fricker LD. Neuropeptide-processing enzymes: applications for drug discovery. The Aaps Journal. 7: E449-55. PMID 16353923 DOI: 10.1208/aapsj070244  1
2005 Che FY, Lim J, Pan H, Biswas R, Fricker LD. Quantitative neuropeptidomics of microwave-irradiated mouse brain and pituitary. Molecular & Cellular Proteomics : McP. 4: 1391-405. PMID 15970582 DOI: 10.1074/mcp.T500010-MCP200  1
2005 Fontenele-Neto JD, Kalinina E, Feng Y, Fricker LD. Identification and distribution of mouse carboxypeptidase A-6. Brain Research. Molecular Brain Research. 137: 132-42. PMID 15950771 DOI: 10.1016/j.molbrainres.2005.02.026  1
2005 Pan H, Nanno D, Che FY, Zhu X, Salton SR, Steiner DF, Fricker LD, Devi LA. Neuropeptide processing profile in mice lacking prohormone convertase-1. Biochemistry. 44: 4939-48. PMID 15779921 DOI: 10.1021/bi047852m  1
2005 Che FY, Fricker LD. Quantitative peptidomics of mouse pituitary: comparison of different stable isotopic tags. Journal of Mass Spectrometry : Jms. 40: 238-49. PMID 15706629 DOI: 10.1002/jms.743  1
2005 Che FY, Yuan Q, Kalinina E, Fricker LD. Peptidomics of Cpe fat/fat mouse hypothalamus: effect of food deprivation and exercise on peptide levels. The Journal of Biological Chemistry. 280: 4451-61. PMID 15572367 DOI: 10.1074/jbc.M411178200  1
2004 Yuan Q, Fontenele-Neto JD, Fricker LD. Effect of voluntary exercise on genetically obese Cpefat/fat mice: quantitative proteomics of serum. Obesity Research. 12: 1179-88. PMID 15292483 DOI: 10.1038/oby.2004.147  1
2004 Che FY, Yuan Q, Kalinina E, Fricker LD. Examination of the rate of peptide biosynthesis in neuroendocrine cell lines using a stable isotopic label and mass spectrometry. Journal of Neurochemistry. 90: 585-94. PMID 15255936 DOI: 10.1111/j.1471-4159.2004.02522.x  1
2004 Wei S, Feng Y, Che FY, Pan H, Mzhavia N, Devi LA, McKinzie AA, Levin N, Richards WG, Fricker LD. Obesity and diabetes in transgenic mice expressing proSAAS. The Journal of Endocrinology. 180: 357-68. PMID 15012590 DOI: 10.1677/joe.0.1800357  1
2004 Srinivasan S, Bunch DO, Feng Y, Rodriguiz RM, Li M, Ravenell RL, Luo GX, Arimura A, Fricker LD, Eddy EM, Wetsel WC. Deficits in reproduction and pro-gonadotropin-releasing hormone processing in male Cpefat mice. Endocrinology. 145: 2023-34. PMID 14715715 DOI: 10.1210/en.2003-1442  1
2004 Fricker LD. Metallocarboxypeptidase D Handbook of Proteolytic Enzymes: Second Edition. 1: 848-851. DOI: 10.1016/B978-0-12-079611-3.50259-7  1
2004 Fricker LD. Carboxypeptidase Z Handbook of Proteolytic Enzymes: Second Edition. 1: 844-846. DOI: 10.1016/B978-0-12-079611-3.50257-3  1
2003 Che FY, Eipper BA, Mains RE, Fricker LD. Quantitative peptidomics of pituitary glands from mice deficient in copper transport. Cellular and Molecular Biology (Noisy-Le-Grand, France). 49: 713-22. PMID 14528907  1
2003 Wei S, Feng Y, Kalinina E, Fricker LD. Neuropeptide-processing carboxypeptidases. Life Sciences. 73: 655-62. PMID 12801587 DOI: 10.1016/S0024-3205(03)00386-2  1
2003 Kalinina EV, Fricker LD. Palmitoylation of carboxypeptidase D. Implications for intracellular trafficking. The Journal of Biological Chemistry. 278: 9244-9. PMID 12643288 DOI: 10.1074/jbc.M209379200  1
2003 Mzhavia N, Pan H, Che FY, Fricker LD, Devi LA. Characterization of endothelin-converting enzyme-2. Implication for a role in the nonclassical processing of regulatory peptides. The Journal of Biological Chemistry. 278: 14704-11. PMID 12560336 DOI: 10.1074/jbc.M211242200  1
2002 Feng Y, Reznik SE, Fricker LD. ProSAAS and prohormone convertase 1 are broadly expressed during mouse development. Brain Research. Gene Expression Patterns. 1: 135-40. PMID 15018810  1
2002 Sidyelyeva G, Fricker LD. Characterization of Drosophila carboxypeptidase D. The Journal of Biological Chemistry. 277: 49613-20. PMID 12393882 DOI: 10.1074/jbc.M209652200  1
2002 Che FY, Fricker LD. Quantitation of neuropeptides in Cpe(fat)/Cpe(fat) mice using differential isotopic tags and mass spectrometry. Analytical Chemistry. 74: 3190-8. PMID 12141682 DOI: 10.1021/ac015681a  1
2002 Kalinina E, Varlamov O, Fricker LD. Analysis of the carboxypeptidase D cytoplasmic domain: Implications in intracellular trafficking. Journal of Cellular Biochemistry. 85: 101-11. PMID 11891854 DOI: 10.1002/jcb.10112  1
2002 Wei S, Segura S, Vendrell J, Aviles FX, Lanoue E, Day R, Feng Y, Fricker LD. Identification and characterization of three members of the human metallocarboxypeptidase gene family. The Journal of Biological Chemistry. 277: 14954-64. PMID 11836249 DOI: 10.1074/jbc.M112254200  1
2002 Mzhavia N, Qian Y, Feng Y, Che FY, Devi LA, Fricker LD. Processing of proSAAS in neuroendocrine cell lines. The Biochemical Journal. 361: 67-76. PMID 11742530 DOI: 10.1042/0264-6021:3610067  1
2002 Fricker LD. 15 Carboxypeptidases E and D Enzymes. 22: 421-452. DOI: 10.1016/S1874-6047(02)80016-6  1
2001 Reznik SE, Fricker LD. Carboxypeptidases from A to z: implications in embryonic development and Wnt binding. Cellular and Molecular Life Sciences : Cmls. 58: 1790-804. PMID 11766880  1
2001 Feng Y, Reznik SE, Fricker LD. Distribution of proSAAS-derived peptides in rat neuroendocrine tissues. Neuroscience. 105: 469-78. PMID 11672612 DOI: 10.1016/S0306-4522(01)00200-7  1
2001 Che FY, Yan L, Li H, Mzhavia N, Devi LA, Fricker LD. Identification of peptides from brain and pituitary of Cpefat/Cpefat mice Proceedings of the National Academy of Sciences of the United States of America. 98: 9971-9976. PMID 11481435 DOI: 10.1073/pnas.161542198  1
2001 Basak A, Koch P, Dupelle M, Fricker LD, Devi LA, Chrétien M, Seidah NG. Inhibitory Specificity and Potency of proSAAS-derived Peptides toward Proprotein Convertase 1 Journal of Biological Chemistry. 276: 32720-32728. PMID 11435430 DOI: 10.1074/jbc.M104064200  1
2001 Novikova E, Fricker LD, Reznik SE. Metallocarboxypeptidase Z is dynamically expressed in mouse development. Mechanisms of Development. 102: 259-62. PMID 11287206 DOI: 10.1016/S0925-4773(01)00306-9  1
2001 Aloy P, Companys V, Vendrell J, Aviles FX, Fricker LD, Coll M, Gomis-Rüth FX. The Crystal Structure of the Inhibitor-complexed Carboxypeptidase D Domain II and the Modeling of Regulatory Carboxypeptidases Journal of Biological Chemistry. 276: 16177-16184. PMID 11278909 DOI: 10.1074/jbc.M011457200  1
2001 Varlamov O, Kalinina E, Che FY, Fricker LD. Protein phosphatase 2A binds to the cytoplasmic tail of carboxypeptidase D and regulates post-trans-Golgi network trafficking Journal of Cell Science. 114: 311-322. PMID 11148133  1
2001 Mzhavia N, Berman Y, Che FY, Fricker LD, Devi LA. ProSAAS Processing in Mouse Brain and Pituitary Journal of Biological Chemistry. 276: 6207-6213. PMID 11094058 DOI: 10.1074/jbc.M009067200  1
2000 Qian Y, Devi LA, Mzhavia N, Munzer S, Seidah NG, Fricker LD. The C-terminal region of proSAAS is a potent inhibitor of prohormone convertase 1 Journal of Biological Chemistry. 275: 23596-23601. PMID 10816562 DOI: 10.1074/jbc.M001583200  1
2000 Novikova EG, Reznik SE, Varlamov O, Fricker LD. Carboxypeptidase Z is present in the regulated secretory pathway and extracellular matrix in cultured cells and in human tissues. The Journal of Biological Chemistry. 275: 4865-70. PMID 10671522 DOI: 10.1074/jbc.275.7.4865  1
2000 Fricker LD, McKinzie AA, Sun J, Curran E, Qian Y, Yan L, Patterson SD, Courchesne PL, Richards B, Levin N, Mzhavia N, Devi LA, Douglass J. Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing Journal of Neuroscience. 20: 639-648. PMID 10632593  1
1999 Gomis-Rüth FX, Companys V, Qian Y, Fricker LD, Vendrell J, Avilés FX, Coll M. Crystal structure of avian carboxypeptidase D domain II: A prototype for the regulatory metallocarboxypeptidase subfamily Embo Journal. 18: 5817-5826. PMID 10545093 DOI: 10.1093/emboj/18.21.5817  1
1999 Novikova EG, Eng FJ, Yan L, Qian Y, Fricker LD. Characterization of the enzymatic properties of the first and second domains of metallocarboxypeptidase D. The Journal of Biological Chemistry. 274: 28887-92. PMID 10506132 DOI: 10.1074/jbc.274.41.28887  1
1999 Fricker LD, Leiter EH. Peptides, enzymes and obesity: New insights from a 'dead' enzyme Trends in Biochemical Sciences. 24: 390-393. PMID 10500303 DOI: 10.1016/S0968-0004(99)01448-6  1
1999 Dong W, Fricker LD, Day R. Carboxypeptidase D is a potential candidate to carry out redundant processing functions of carboxypeptidase E based on comparative distribution studies in the rat central nervous system Neuroscience. 89: 1301-1317. PMID 10362316 DOI: 10.1016/S0306-4522(98)00381-9  1
1999 Varlamov O, Eng FJ, Novikova EG, Fricker LD. Localization of metallocarboxypeptidase D in AtT-20 cells. Potential role in prohormone processing. The Journal of Biological Chemistry. 274: 14759-67. PMID 10329672 DOI: 10.1074/jbc.274.21.14759  1
1999 Varlamov O, Wu F, Shields D, Fricker LD. Biosynthesis and packaging of carboxypeptidase D into nascent secretory vesicles in pituitary cell lines Journal of Biological Chemistry. 274: 14040-14045. PMID 10318817 DOI: 10.1074/jbc.274.20.14040  1
1999 Qian Y, Varlamov O, Fricker LD. Glu300 of rat carboxypeptidase E is essential for enzymatic activity but not substrate binding or routing to the regulated secretory pathway Journal of Biological Chemistry. 274: 11582-11586. PMID 10206965 DOI: 10.1074/jbc.274.17.11582  1
1999 Novikova EG, Fricker LD. Purification and characterization of human metallocarboxypeptidase Z Biochemical and Biophysical Research Communications. 256: 564-568. PMID 10080937 DOI: 10.1006/bbrc.1999.0378  1
1999 Lei Y, Xin X, Morgan D, Pintar JE, Fricker LD. Identification of mouse CPX-1, a novel member of the metallocarboxypeptidase gene family with highest similarity to CPX-2. Dna and Cell Biology. 18: 175-85. PMID 10073577 DOI: 10.1089/104454999315565  1
1999 Fan X, Qian Y, Fricker LD, Akalal DBG, Nagle GT. Cloning and expression of Aplysia carboxypeptidase D, a candidate prohormone-processing enzyme Dna and Cell Biology. 18: 121-132. PMID 10073571 DOI: 10.1089/104454999315501  1
1999 Eng FJ, Varlamov O, Fricker LD. Sequences within the cytoplasmic domain of gp180/carboxypeptidase D mediate localization to the trans-Golgi network. Molecular Biology of the Cell. 10: 35-46. PMID 9880325  1
1998 Reznik SE, Salafia CM, Lage JM, Fricker LD. Immunohistochemical localization of carboxypeptidases E and D in the human placenta and umbilical cord. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 46: 1359-68. PMID 9815277  1
1998 Eng FJ, Novikova EG, Kuroki K, Ganem D, Fricker LD. gp180, a protein that binds duck hepatitis B virus particles, has metallocarboxypeptidase D-like enzymatic activity. The Journal of Biological Chemistry. 273: 8382-8. PMID 9525948 DOI: 10.1074/jbc.273.14.8382  1
1998 Varlamov O, Fricker LD. Intracellular trafficking of metallocarboxypeptidase D in AtT-20 cells: Localization to the trans-Golgi network and recycling from the cell surface Journal of Cell Science. 111: 877-885. PMID 9490632  1
1997 Varlamov O, Fricker LD, Furukawa H, Steiner DF, Langley SH, Leiter EH. β-cell lines derived from transgenic Cpe(fat)/Cpe(fat) mice are defective in carboxypeptidase E and proinsulin processing Endocrinology. 138: 4883-4892. PMID 9348219 DOI: 10.1210/en.138.11.4883  1
1997 Juvvadi S, Fan X, Nagle GT, Fricker LD. Characterization of Aplysia carboxypeptidase E Febs Letters. 408: 195-200. PMID 9187366 DOI: 10.1016/S0014-5793(97)00426-2  1
1997 Song L, Fricker LD. The pro region is not required for the expression or intracellular routeing of carboxypeptidase E Biochemical Journal. 323: 265-271. PMID 9173892  1
1997 Udupi V, Gomez P, Song L, Varlamov O, Reed JT, Leiter EH, Fricker LD, Greeley GH. Effect of carboxypeptidase E deficiency on progastrin processing and gastrin messenger ribonucleic acid expression in mice with the fat mutation. Endocrinology. 138: 1959-63. PMID 9112393 DOI: 10.1210/endo.138.5.5113  1
1997 Song L, Fricker LD. Cloning and expression of human carboxypeptidase Z, a novel metallocarboxypeptidase Journal of Biological Chemistry. 272: 10543-10550. PMID 9099699 DOI: 10.1074/jbc.272.16.10543  1
1996 Fricker LD, Berman YL, Leiter EH, Devi LA. Carboxypeptidase E activity is deficient in mice with the fat mutation: Effect on peptide processing Journal of Biological Chemistry. 271: 30619-30624. PMID 8940036 DOI: 10.1074/jbc.271.48.30619  1
1996 Song L, Fricker LD. Tissue distribution and characterization of soluble and membrane-bound forms of metallocarboxypeptidase D Journal of Biological Chemistry. 271: 28884-28889. PMID 8910535 DOI: 10.1074/jbc.271.46.28884  1
1996 Varlamov O, Fricker LD. The C-terminal region of carboxypeptidase E involved in membrane binding is distinct from the region involved with intracellular routing Journal of Biological Chemistry. 271: 6077-6083. PMID 8626393 DOI: 10.1074/jbc.271.11.6077  1
1995 Song L, Fricker LD. Calcium- and pH-dependent aggregation of carboxypeptidase E Journal of Biological Chemistry. 270: 7963-7967. PMID 7713894 DOI: 10.1074/jbc.270.14.7963  1
1995 Naggert JK, Fricker LD, Varlamov O, Nishina PM, Rouille Y, Steiner DF, Carroll RJ, Paigen BJ, Leiter EH. Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity Nature Genetics. 10: 135-142. PMID 7663508 DOI: 10.1038/ng0695-135  1
1995 Song L, Fricker LD. Purification and characterization of carboxypeptidase D, a novel carboxypeptidase E-like enzyme, from bovine pituitary Journal of Biological Chemistry. 270: 25007-25013. PMID 7559630 DOI: 10.1074/jbc.270.42.25007  1
1995 Fricker LD. [13] Methods for studying carboxypeptidase E Methods in Neurosciences. 23: 237-250. DOI: 10.1016/S1043-9471(06)80124-2  1
1994 Nalamachu SR, Song L, Fricker LD. Regulation of carboxypeptidase E: Effect of Ca2+ on enzyme activity and stability Journal of Biological Chemistry. 269: 11192-11195. PMID 8157647  1
1994 Mitra A, Song L, Fricker LD. The C-terminal region of carboxypeptidase E is involved in membrane binding and intracellular routing in AtT-20 cells Journal of Biological Chemistry. 269: 19876-19881. PMID 8051069  1
1994 Jung YK, Fricker LD. Expression of the carboxypeptidase E gene: Characterization of the initiator-binding proteins Biochimie. 76: 336-345. PMID 7819345 DOI: 10.1016/0300-9084(94)90168-6  1
1993 Klein RS, Fricker LD. Differential effects of a phorbol ester on carboxypeptidase E in cultured astrocytes and AtT-20 cells, a neuroendocrine cell line. Journal of Neurochemistry. 60: 1615-25. PMID 8473886  1
1993 Gee P, Rhodes CH, Fricker LD, Angeletti RH. Expression of neuropeptide processing enzymes and neurosecretory proteins in ependyma and choroid plexus epithelium. Brain Research. 617: 238-48. PMID 8402152 DOI: 10.1016/0006-8993(93)91091-6  1
1993 Fricker LD, Devi L. Posttranslational processing of carboxypeptidase E, a neuropeptide-processing enzyme, in AtT-20 cells and bovine pituitary secretory granules Journal of Neurochemistry. 61: 1404-1415. PMID 8376994  1
1993 Grigoriants O, Devi L, Fricker LD. Dopamine antagonist haloperidol increases carboxypeptidase E mRNA in rat neurointermediate pituitary but not in various other rat tissues Molecular Brain Research. 19: 161-164. PMID 8361339 DOI: 10.1016/0169-328X(93)90162-I  1
1992 Greene D, Das B, Fricker LD. Regulation of carboxypeptidase E. Effect of pH, temperature and Co2+ on kinetic parameters of substrate hydrolysis Biochemical Journal. 285: 613-618. PMID 1637350  1
1992 Klein RS, Das B, Fricker LD. Secretion of carboxypeptidase E from cultured astrocytes and from AtT-20 cells, a neuroendocrine cell line: implications for neuropeptide biosynthesis. Journal of Neurochemistry. 58: 2011-8. PMID 1573389  1
1992 Klein RS, Fricker LD. Heterogeneous expression of carboxypeptidase E and proenkephalin mRNAs by cultured astrocytes. Brain Research. 569: 300-10. PMID 1540832 DOI: 10.1016/0006-8993(92)90643-N  1
1992 Jung YK, Kunczt CJ, Pearson RK, Fricker LD, Dixon JE. Expression of the rat carboxypeptidase-E gene in neuroendocrine and nonneuroendocrine cell lines Molecular Endocrinology. 6: 2027-2037. PMID 1491689 DOI: 10.1210/MEND.6.12.1491689  1
1992 Klein RS, Fricker LD. Cultured astrocytes express mRNA for peptidylglycine-alpha-amidating monooxygenase, a neuropeptide processing enzyme. Brain Research. 596: 202-8. PMID 1467983 DOI: 10.1016/0006-8993(92)91548-S  1
1991 Fricker LD, Das B, Klein RS, Greene D, Jung YK. Regulation of carboxypeptidase E (enkephalin convertase). Nida Research Monograph. 111: 171-87. PMID 1775180  1
1991 Jung YK, Kunczt CJ, Pearson RK, Dixon JE, Fricker LD. Structural characterization of the rat carboxypeptidase-E gene Molecular Endocrinology. 5: 1257-1268. PMID 1770952 DOI: 10.1210/MEND-5-9-1257  1
1990 Fricker LD, Devi L. Comparison of a spectrophotometric, a fluorometric, and a novel radiometric assay for carboxypeptidase E (EC 3.4.17.10) and other carboxypeptidase B-like enzymes Analytical Biochemistry. 184: 21-27. PMID 2321755 DOI: 10.1016/0003-2697(90)90005-T  1
1990 Fricker LD, Das B, Angeletti RH. Identification of the pH-dependent membrane anchor of carboxypeptidase E (EC 3.4.17.10) Journal of Biological Chemistry. 265: 2476-2482. PMID 2303412  1
1990 Fricker LD, Reaves BJ, Das B, Dannies PS. Comparison of the regulation of carboxypeptidase e and prolactin in GH<inf>4</inf>C<inf>1</inf> cells, a rat pituitary cell line Neuroendocrinology. 51: 658-663. PMID 2114002 DOI: 10.1159/000125407  1
1989 Fricker LD, Adelman JP, Douglass J, Thompson RC, Von Strandmann RP, Hutton J. Isolation and sequence analysis of cDNA for rat carboxypeptidase E [EC 3.4.17.10], a neuropeptide processing enzyme Molecular Endocrinology. 3: 666-673. PMID 2725530  1
1989 Hutton JC, Guest PC, Rhodes CJ, Fricker LD, Grimaldi KA, Siddle K, Davidson W, Bailyes EM. Biogenesis of the insulin secretion granule Journees Annuelles De Diabetologie De L"Hotel-Dieu. 13-28. PMID 2548031  1
1989 Smyth DG, Maruthainar K, Darby NJ, Fricker LD. Catalysis of Slow C‐Terminal Processing Reactions by Carboxypeptidase H Journal of Neurochemistry. 53: 489-493. PMID 2526198 DOI: 10.1111/j.1471-4159.1989.tb07360.x  1
1988 Fricker LD, Herbert E. Comparison of a carboxypeptidase E-like enzyme in human, bovine, mouse, Xenopus, shark and Aplysia neural tissue. Brain Research. 453: 281-6. PMID 3401766 DOI: 10.1016/0006-8993(88)90168-0  1
1988 Supattapone S, Strittmatter SM, Fricker LD, Snyder SH. Characterization of a neutral, divalent cation-sensitive endopeptidase: a possible role in neuropeptide processing. Brain Research. 427: 173-81. PMID 3382941 DOI: 10.1016/0169-328X(88)90063-0  1
1988 Fricker LD. Activation and membrane binding of carboxypeptidase E Journal of Cellular Biochemistry. 38: 279-289. PMID 3149282 DOI: 10.1002/jcb.240380407  1
1988 Fricker LD. Carboxypeptidase E Annual Review of Physiology. 50: 309-321. PMID 2897826 DOI: 10.1016/B978-0-12-382219-2.00301-X  1
1986 Fricker LD, Evans CJ, Esch FS, Herbert E. Cloning and sequence analysis of cDNA for bovine carboxypeptidase E. Nature. 323: 461-4. PMID 3020433 DOI: 10.1038/323461a0  1
1985 Hook VY, Mezey E, Fricker LD, Pruss RM, Siegel RE, Brownstein MJ. Immunochemical characterization of carboxypeptidase B-like peptide-hormone-processing enzyme. Proceedings of the National Academy of Sciences of the United States of America. 82: 4745-9. PMID 3927290 DOI: 10.1073/pnas.82.14.4745  1
1985 Fricker LD. Neuropeptide biosynthesis: focus on the carboxypeptidase processing enzyme Trends in Neurosciences. 8: 210-214. DOI: 10.1016/0166-2236(85)90081-5  1
1984 Supattapone S, Fricker LD, Snyder SH. Purification and Characterization of a Membrane‐Bound Enkephalin‐Forming Carboxypeptidase, “Enkephalin Convertase” Journal of Neurochemistry. 42: 1017-1023. PMID 6421996 DOI: 10.1111/j.1471-4159.1984.tb12705.x  1
1984 Stack G, Fricker LD, Snyder SH. A sensitive radiometric assay for enkephalin convertase and other carboxypeptidase B-like enzymes Life Sciences. 34: 113-121. PMID 6420632 DOI: 10.1016/0024-3205(84)90581-2  1
1984 Kapiloff MS, Strittmatter SM, Fricker LD, Snyder SH. A fluorometric assay for angiotensin-converting enzyme activity. Analytical Biochemistry. 140: 293-302. PMID 6091493 DOI: 10.1016/0003-2697(84)90167-2  1
1983 Fricker LD, Snyder SH. Purification and characterization of enkephalin convertase, an enkephalin-synthesizing carboxypeptidase Journal of Biological Chemistry. 258: 10950-10955. PMID 6411723  1
1983 Fricker LD, Plummer TH, Snyder SH. Enkephalin convertase: Potent, selective, and irreversible inhibitors Biochemical and Biophysical Research Communications. 111: 994-1000. PMID 6404277 DOI: 10.1016/0006-291X(83)91398-0  1
1982 Fricker LD, Supattapone S, Snyder SH. Enkephalin convertase: A specific enkephalin synthesizing carboxypeptidase in adrenal chromaffin granules, brain, and pituitary gland Life Sciences. 31: 1841-1844. PMID 6818411 DOI: 10.1016/0024-3205(82)90224-7  1
1982 Fricker LD, Snyder SH. Enkephalin convertase: Purification and characterization of a specific enkephalin-synthesizing carboxypeptidase localized to adrenal chromaffin granules Proceedings of the National Academy of Sciences of the United States of America. 79: 3886-3890. PMID 6808517 DOI: 10.1073/PNAS.79.12.3886  1
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