Philip N. Tsichlis - Publications

Affiliations: 
Biochemistry Sackler School of Graduate Biomedical Sciences (Tufts University) 
Area:
Biochemistry

171 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Voulgarelis M, Tsichlis PN. Proline hydroxylation linked to Akt activation. Science (New York, N.Y.). 353: 870-1. PMID 27563086 DOI: 10.1126/science.aah6254  0.4
2016 Vyrla D, Nikolaidis G, Oakley F, Perugorria MJ, Tsichlis PN, Mann DA, Eliopoulos AG. TPL2 Kinase Is a Crucial Signaling Factor and Mediator of NKT Effector Cytokine Expression in Immune-Mediated Liver Injury. Journal of Immunology (Baltimore, Md. : 1950). PMID 27053764 DOI: 10.4049/jimmunol.1501609  0.4
2015 Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, ... Tsichlis PN, et al. MicroRNA214 is Associated with Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-associated Cancer in Mice. Gastroenterology. PMID 26055138 DOI: 10.1053/j.gastro.2015.05.057  0.4
2015 Richardson ET, Shukla S, Sweet DR, Wearsch PA, Tsichlis PN, Boom WH, Harding CV. Toll-like receptor 2-dependent extracellular signal-regulated kinase signaling in Mycobacterium tuberculosis-infected macrophages drives anti-inflammatory responses and inhibits Th1 polarization of responding T cells. Infection and Immunity. 83: 2242-54. PMID 25776754 DOI: 10.1128/IAI.00135-15  0.4
2015 Kanellis DC, Bursac S, Tsichlis PN, Volarevic S, Eliopoulos AG. Physical and functional interaction of the TPL2 kinase with nucleophosmin Oncogene. 34: 2516-2526. PMID 24998852 DOI: 10.1038/onc.2014.183  0.4
2014 Kottakis F, Foltopoulou P, Sanidas I, Keller P, Wronski A, Dake BT, Ezell SA, Shen Z, Naber SP, Hinds PW, McNiel E, Kuperwasser C, Tsichlis PN. NDY1/KDM2B functions as a master regulator of polycomb complexes and controls self-renewal of breast cancer stem cells. Cancer Research. 74: 3935-46. PMID 24853546 DOI: 10.1158/0008-5472.CAN-13-2733  0.4
2014 Sourvinos G, Morou A, Sanidas I, Codruta I, Ezell SA, Doxaki C, Kampranis SC, Kottakis F, Tsichlis PN. The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the transition to productive infection. Plos Pathogens. 10: e1004136. PMID 24830456 DOI: 10.1371/journal.ppat.1004136  0.4
2014 Sriskantharajah S, Gückel E, Tsakiri N, Kierdorf K, Brender C, Ben-Addi A, Veldhoen M, Tsichlis PN, Stockinger B, O'Garra A, Prinz M, Kollias G, Ley SC. Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase. Journal of Immunology (Baltimore, Md. : 1950). 192: 3518-29. PMID 24639351 DOI: 10.4049/jimmunol.1300172  0.4
2014 Roper J, Sinnamon MJ, Coffee EM, Belmont P, Keung L, Georgeon-Richard L, Wang WV, Faber AC, Yun J, Yilmaz ÖH, Bronson RT, Martin ES, Tsichlis PN, Hung KE. Combination PI3K/MEK inhibition promotes tumor apoptosis and regression in PIK3CA wild-type, KRAS mutant colorectal cancer. Cancer Letters. 347: 204-11. PMID 24576621 DOI: 10.1016/j.canlet.2014.02.018  0.4
2014 Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, Anderson SM, Tsichlis PN, Leone G, Wagner KU. Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis. Molecular and Cellular Biology. 34: 1363-77. PMID 24469394 DOI: 10.1128/MCB.01220-13  0.4
2014 Sanidas I, Polytarchou C, Hatziapostolou M, Ezell SA, Kottakis F, Hu L, Guo A, Xie J, Comb MJ, Iliopoulos D, Tsichlis PN. Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer. Molecular Cell. 53: 577-90. PMID 24462114 DOI: 10.1016/j.molcel.2013.12.018  0.4
2014 Corum DG, Tsichlis PN, Muise-Helmericks RC. AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 395-407. PMID 24081905 DOI: 10.1096/fj.13-235382  0.4
2013 Kyrmizi I, Ioannou M, Hatziapostolou M, Tsichlis PN, Boumpas DT, Tassiulas I. Tpl2 kinase regulates FcγR signaling and immune thrombocytopenia in mice. Journal of Leukocyte Biology. 94: 751-7. PMID 23898046 DOI: 10.1189/jlb.0113039  0.4
2013 Luo C, Sheng J, Hu MG, Haluska FG, Cui R, Xu Z, Tsichlis PN, Hu GF, Hinds PW. Loss of ARF sensitizes transgenic BRAFV600E mice to UV-induced melanoma via suppression of XPC. Cancer Research. 73: 4337-48. PMID 23650282 DOI: 10.1158/0008-5472.CAN-12-4454  0.4
2013 Gkirtzimanaki K, Gkouskou KK, Oleksiewicz U, Nikolaidis G, Vyrla D, Liontos M, Pelekanou V, Kanellis DC, Evangelou K, Stathopoulos EN, Field JK, Tsichlis PN, Gorgoulis V, Liloglou T, Eliopoulos AG. TPL2 kinase is a suppressor of lung carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: E1470-9. PMID 23533274 DOI: 10.1073/pnas.1215938110  0.4
2012 Ezell SA, Tsichlis PN. Akt1, EMSY, BRCA2 and type I IFN signaling: a novel arm of the IFN response. Transcription. 3: 305-9. PMID 23117821 DOI: 10.4161/trns.21904  0.4
2012 Arranz A, Doxaki C, Vergadi E, Martinez de la Torre Y, Vaporidi K, Lagoudaki ED, Ieronymaki E, Androulidaki A, Venihaki M, Margioris AN, Stathopoulos EN, Tsichlis PN, Tsatsanis C. Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization. Proceedings of the National Academy of Sciences of the United States of America. 109: 9517-22. PMID 22647600 DOI: 10.1073/pnas.1119038109  0.4
2012 Serebrennikova OB, Tsatsanis C, Mao C, Gounaris E, Ren W, Siracusa LD, Eliopoulos AG, Khazaie K, Tsichlis PN. Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation. Proceedings of the National Academy of Sciences of the United States of America. 109: E1082-91. PMID 22451924 DOI: 10.1073/pnas.1115098109  0.4
2012 Ezell SA, Polytarchou C, Hatziapostolou M, Guo A, Sanidas I, Bihani T, Comb MJ, Sourvinos G, Tsichlis PN. The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY. Proceedings of the National Academy of Sciences of the United States of America. 109: E613-21. PMID 22315412 DOI: 10.1073/pnas.1115029109  0.4
2012 Gugasyan R, Horat E, Kinkel SA, Ross F, Grigoriadis G, Gray D, O'Keeffe M, Berzins SP, Belz GT, Grumont RJ, Banerjee A, Strasser A, Godfrey DI, Tsichlis PN, Gerondakis S. The NF-κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory properties. The Embo Journal. 31: 692-706. PMID 22124325 DOI: 10.1038/emboj.2011.435  0.4
2011 Hatziapostolou M, Koukos G, Polytarchou C, Kottakis F, Serebrennikova O, Kuliopulos A, Tsichlis PN. Tumor progression locus 2 mediates signal-induced increases in cytoplasmic calcium and cell migration. Science Signaling. 4: ra55. PMID 21868363 DOI: 10.1126/scisignal.2002006  0.4
2011 Polytarchou C, Iliopoulos D, Hatziapostolou M, Kottakis F, Maroulakou I, Struhl K, Tsichlis PN. Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation. Cancer Research. 71: 4720-31. PMID 21555366 DOI: 10.1158/0008-5472.CAN-11-0365  0.4
2011 Perfield JW, Lee Y, Shulman GI, Samuel VT, Jurczak MJ, Chang E, Xie C, Tsichlis PN, Obin MS, Greenberg AS. Tumor progression locus 2 (TPL2) regulates obesity-associated inflammation and insulin resistance. Diabetes. 60: 1168-76. PMID 21346175 DOI: 10.2337/db10-0715  0.4
2010 Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K. Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Molecular Cell. 39: 761-72. PMID 20832727 DOI: 10.1016/j.molcel.2010.08.013  0.4
2010 Hirsch HA, Iliopoulos D, Joshi A, Zhang Y, Jaeger SA, Bulyk M, Tsichlis PN, Shirley Liu X, Struhl K. A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases. Cancer Cell. 17: 348-61. PMID 20385360 DOI: 10.1016/j.ccr.2010.01.022  0.4
2010 Watford WT, Wang CC, Tsatsanis C, Mielke LA, Eliopoulos AG, Daskalakis C, Charles N, Odom S, Rivera J, O'Shea J, Tsichlis PN. Ablation of tumor progression locus 2 promotes a type 2 Th cell response in Ovalbumin-immunized mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 105-13. PMID 19955521 DOI: 10.4049/jimmunol.0803730  0.4
2009 Mielke LA, Elkins KL, Wei L, Starr R, Tsichlis PN, O'Shea JJ, Watford WT. Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1 beta production. Journal of Immunology (Baltimore, Md. : 1950). 183: 7984-93. PMID 19933865 DOI: 10.4049/jimmunol.0901336  0.4
2009 Iliopoulos D, Polytarchou C, Hatziapostolou M, Kottakis F, Maroulakou IG, Struhl K, Tsichlis PN. MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells. Science Signaling. 2: ra62. PMID 19825827 DOI: 10.1126/scisignal.2000356  0.4
2009 Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Research. 69: 7507-11. PMID 19752085 DOI: 10.1158/0008-5472.CAN-09-2994  0.4
2009 Androulidaki A, Iliopoulos D, Arranz A, Doxaki C, Schworer S, Zacharioudaki V, Margioris AN, Tsichlis PN, Tsatsanis C. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity. 31: 220-31. PMID 19699171 DOI: 10.1016/j.immuni.2009.06.024  0.4
2009 Kaiser F, Cook D, Papoutsopoulou S, Rajsbaum R, Wu X, Yang HT, Grant S, Ricciardi-Castagnoli P, Tsichlis PN, Ley SC, O'Garra A. TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells. The Journal of Experimental Medicine. 206: 1863-71. PMID 19667062 DOI: 10.1084/jem.20091059  0.4
2009 Kampranis SC, Tsichlis PN. Histone demethylases and cancer. Advances in Cancer Research. 102: 103-69. PMID 19595308 DOI: 10.1016/S0065-230X(09)02004-1  0.4
2009 Tzatsos A, Pfau R, Kampranis SC, Tsichlis PN. Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus. Proceedings of the National Academy of Sciences of the United States of America. 106: 2641-6. PMID 19202064 DOI: 10.1073/pnas.0813139106  0.4
2009 Hu MG, Deshpande A, Enos M, Mao D, Hinds EA, Hu GF, Chang R, Guo Z, Dose M, Mao C, Tsichlis PN, Gounari F, Hinds PW. A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis. Cancer Research. 69: 810-8. PMID 19155308 DOI: 10.1158/0008-5472.CAN-08-2473  0.4
2009 Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission (Cancer Research (2009) 69, (7507-7511)) Cancer Research. 69: 8832. DOI: 10.1158/0008-5472.CAN-09-3869  0.4
2008 Watford WT, Hissong BD, Durant LR, Yamane H, Muul LM, Kanno Y, Tato CM, Ramos HL, Berger AE, Mielke L, Pesu M, Solomon B, Frucht DM, Paul WE, Sher A, ... ... Tsichlis PN, et al. Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii. The Journal of Experimental Medicine. 205: 2803-12. PMID 19001140 DOI: 10.1084/jem.20081461  0.4
2008 Polytarchou C, Pfau R, Hatziapostolou M, Tsichlis PN. The JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stress. Molecular and Cellular Biology. 28: 7451-64. PMID 18838535 DOI: 10.1128/MCB.00688-08  0.4
2008 Maroulakou IG, Oemler W, Naber SP, Klebba I, Kuperwasser C, Tsichlis PN. Distinct roles of the three Akt isoforms in lactogenic differentiation and involution. Journal of Cellular Physiology. 217: 468-77. PMID 18561256 DOI: 10.1002/jcp.21518  0.4
2008 Wright GL, Maroulakou IG, Eldridge J, Liby TL, Sridharan V, Tsichlis PN, Muise-Helmericks RC. VEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3264-75. PMID 18524868 DOI: 10.1096/fj.08-106468  0.4
2008 Hatziapostolou M, Polytarchou C, Panutsopulos D, Covic L, Tsichlis PN. Proteinase-activated receptor-1-triggered activation of tumor progression locus-2 promotes actin cytoskeleton reorganization and cell migration. Cancer Research. 68: 1851-61. PMID 18339866 DOI: 10.1158/0008-5472.CAN-07-5793  0.4
2008 Tsatsanis C, Vaporidi K, Zacharioudaki V, Androulidaki A, Sykulev Y, Margioris AN, Tsichlis PN. Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 2987-92. PMID 18287049 DOI: 10.1073/pnas.0708381104  0.4
2008 Pfau R, Tzatsos A, Kampranis SC, Serebrennikova OB, Bear SE, Tsichlis PN. Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process. Proceedings of the National Academy of Sciences of the United States of America. 105: 1907-12. PMID 18250326 DOI: 10.1073/pnas.0711865105  0.4
2007 Odat O, Matta S, Khalil H, Kampranis SC, Pfau R, Tsichlis PN, Makris AM. Old yellow enzymes, highly homologous FMN oxidoreductases with modulating roles in oxidative stress and programmed cell death in yeast. The Journal of Biological Chemistry. 282: 36010-23. PMID 17897954 DOI: 10.1074/jbc.M704058200  0.4
2007 Robinson MJ, Beinke S, Kouroumalis A, Tsichlis PN, Ley SC. Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages. Molecular and Cellular Biology. 27: 7355-64. PMID 17709378 DOI: 10.1128/MCB.00301-07  0.4
2007 Van Acker GJ, Perides G, Weiss ER, Das S, Tsichlis PN, Steer ML. Tumor progression locus-2 is a critical regulator of pancreatic and lung inflammation during acute pancreatitis. The Journal of Biological Chemistry. 282: 22140-9. PMID 17537724 DOI: 10.1074/jbc.M702225200  0.4
2007 Black TM, Andrews CL, Kilili G, Ivan M, Tsichlis PN, Vouros P. Characterization of phosphorylation sites on Tpl2 using IMAC enrichment and a linear ion trap mass spectrometer. Journal of Proteome Research. 6: 2269-76. PMID 17472361 DOI: 10.1021/pr0700293  0.4
2007 Tzatsos A, Tsichlis PN. Energy depletion inhibits phosphatidylinositol 3-kinase/Akt signaling and induces apoptosis via AMP-activated protein kinase-dependent phosphorylation of IRS-1 at Ser-794. The Journal of Biological Chemistry. 282: 18069-82. PMID 17459875 DOI: 10.1074/jbc.M610101200  0.4
2007 Mao C, Tili EG, Dose M, Haks MC, Bear SE, Maroulakou I, Horie K, Gaitanaris GA, Fidanza V, Ludwig T, Wiest DL, Gounari F, Tsichlis PN. Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition. Journal of Immunology (Baltimore, Md. : 1950). 178: 5443-53. PMID 17442925  0.4
2007 Tsichlis PN, Hatziapostolou M, Hinds PW. Timing is everything: regulation of Cdk1 and aneuploidy. Developmental Cell. 12: 477-9. PMID 17419986 DOI: 10.1016/j.devcel.2007.03.010  0.4
2007 Maroulakou IG, Oemler W, Naber SP, Tsichlis PN. Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice. Cancer Research. 67: 167-77. PMID 17210696 DOI: 10.1158/0008-5472.CAN-06-3782  0.4
2006 Tomczak MF, Gadjeva M, Wang YY, Brown K, Maroulakou I, Tsichlis PN, Erdman SE, Fox JG, Horwitz BH. Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-kappaB is responsible for elevated expression of IL-12 p40 observed after challenge with Helicobacter hepaticus. Journal of Immunology (Baltimore, Md. : 1950). 176: 1244-51. PMID 16394015  0.4
2006 Shao Z, Bhattacharya K, Hsich E, Park L, Walters B, Germann U, Wang YM, Kyriakis J, Mohanlal R, Kuida K, Namchuk M, Salituro F, Yao YM, Hou WM, Chen X, ... ... Tsichlis PN, et al. c-Jun N-terminal kinases mediate reactivation of Akt and cardiomyocyte survival after hypoxic injury in vitro and in vivo. Circulation Research. 98: 111-8. PMID 16306447 DOI: 10.1161/01.RES.0000197781.20524.b9  0.4
2006 Eliopoulos AG, Das S, Tsichlis PN. The tyrosine kinase Syk regulates TPL2 activation signals. The Journal of Biological Chemistry. 281: 1371-80. PMID 16291755 DOI: 10.1074/jbc.M506790200  0.4
2006 Cittadini A, Monti MG, Iaccarino G, Di Rella F, Tsichlis PN, Di Gianni A, Strömer H, Sorriento D, Peschle C, Trimarco B, Saccà L, Condorelli G. Adenoviral gene transfer of Akt enhances myocardial contractility and intracellular calcium handling Gene Therapy. 13: 8-19. PMID 16094411 DOI: 10.1038/sj.gt.3302589  0.4
2005 Du K, Tsichlis PN. Regulation of the Akt kinase by interacting proteins. Oncogene. 24: 7401-9. PMID 16288287 DOI: 10.1038/sj.onc.1209099  0.4
2005 Testa JR, Tsichlis PN. AKT signaling in normal and malignant cells. Oncogene. 24: 7391-3. PMID 16288285 DOI: 10.1038/sj.onc.1209100  0.4
2005 Vaporidi K, Tsatsanis C, Georgopoulos D, Tsichlis PN. Effects of hypoxia and hypercapnia on surfactant protein expression proliferation and apoptosis in A549 alveolar epithelial cells. Life Sciences. 78: 284-93. PMID 16125734 DOI: 10.1016/j.lfs.2005.04.070  0.4
2005 Das S, Cho J, Lambertz I, Kelliher MA, Eliopoulos AG, Du K, Tsichlis PN. Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner. The Journal of Biological Chemistry. 280: 23748-57. PMID 15833743 DOI: 10.1074/jbc.M412837200  0.4
2005 Cho J, Melnick M, Solidakis GP, Tsichlis PN. Tpl2 (tumor progression locus 2) phosphorylation at Thr290 is induced by lipopolysaccharide via an Ikappa-B Kinase-beta-dependent pathway and is required for Tpl2 activation by external signals. The Journal of Biological Chemistry. 280: 20442-8. PMID 15778223 DOI: 10.1074/jbc.M413554200  0.4
2005 Cho J, Tsichlis PN. Phosphorylation at Thr-290 regulates Tpl2 binding to NF-kappaB1/p105 and Tpl2 activation and degradation by lipopolysaccharide. Proceedings of the National Academy of Sciences of the United States of America. 102: 2350-5. PMID 15699325 DOI: 10.1073/pnas.0409856102  0.4
2004 Bieganowski P, Shilinski K, Tsichlis PN, Brenner C. Cdc123 and checkpoint forkhead associated with RING proteins control the cell cycle by controlling eIF2gamma abundance. The Journal of Biological Chemistry. 279: 44656-66. PMID 15319434 DOI: 10.1074/jbc.M406151200  0.4
2004 Doan LL, Porter SD, Duan Z, Flubacher MM, Montoya D, Tsichlis PN, Horwitz M, Gilks CB, Grimes HL. Targeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cells. Nucleic Acids Research. 32: 2508-19. PMID 15131254 DOI: 10.1093/nar/gkh570  0.4
2003 Eliopoulos AG, Wang CC, Dumitru CD, Tsichlis PN. Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40. The Embo Journal. 22: 3855-64. PMID 12881420 DOI: 10.1093/emboj/cdg386  0.4
2003 Grille SJ, Bellacosa A, Upson J, Klein-Szanto AJ, van Roy F, Lee-Kwon W, Donowitz M, Tsichlis PN, Larue L. The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Research. 63: 2172-8. PMID 12727836  0.4
2003 Hoyal CR, Gutierrez A, Young BM, Catz SD, Lin JH, Tsichlis PN, Babior BM. Modulation of p47PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase. Proceedings of the National Academy of Sciences of the United States of America. 100: 5130-5. PMID 12704229 DOI: 10.1073/pnas.1031526100  0.4
2003 Doan LL, Kitay MK, Yu Q, Singer A, Herblot S, Hoang T, Bear SE, Morse HC, Tsichlis PN, Grimes HL. Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment. Journal of Immunology (Baltimore, Md. : 1950). 170: 2356-66. PMID 12594258  0.4
2002 Eliopoulos AG, Dumitru CD, Wang CC, Cho J, Tsichlis PN. Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals. The Embo Journal. 21: 4831-40. PMID 12234923 DOI: 10.1093/emboj/cdf478  0.4
2002 Das S, Lin JH, Papamatheakis J, Sykulev Y, Tsichlis PN. Differential splicing generates Tvl-1/RFXANK isoforms with different functions. The Journal of Biological Chemistry. 277: 45172-80. PMID 12215433 DOI: 10.1074/jbc.M204117200  0.4
2002 Chan TO, Rodeck U, Chan AM, Kimmelman AC, Rittenhouse SE, Panayotou G, Tsichlis PN. Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit. Cancer Cell. 1: 181-91. PMID 12086876 DOI: 10.1016/S1535-6108(02)00033-8  0.4
2002 Zhu J, Guo L, Min B, Watson CJ, Hu-Li J, Young HA, Tsichlis PN, Paul WE. Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation. Immunity. 16: 733-44. PMID 12049724 DOI: 10.1016/S1074-7613(02)00317-5  0.4
2002 Eliopoulos AG, Davies C, Blake SS, Murray P, Najafipour S, Tsichlis PN, Young LS. The oncogenic protein kinase Tpl-2/Cot contributes to Epstein-Barr virus-encoded latent infection membrane protein 1-induced NF-kappaB signaling downstream of TRAF2. Journal of Virology. 76: 4567-79. PMID 11932422 DOI: 10.1128/JVI.76.9.4567-4579.2002  0.4
2001 Chan TO, Tsichlis PN. PDK2: a complex tail in one Akt Science"S Stke [Electronic Resource] : Signal Transduction Knowledge Environment. 2001. PMID 11752635  0.4
2001 Malstrom S, Tili E, Kappes D, Ceci JD, Tsichlis PN. Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus Proceedings of the National Academy of Sciences of the United States of America. 98: 14967-14972. PMID 11752445 DOI: 10.1073/pnas.231467698  0.4
2001 Sun M, Wang G, Paciga JE, Feldman RI, Yuan ZQ, Ma XL, Shelley SA, Jove R, Tsichlis PN, Nicosia SV, Cheng JQ. AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells. The American Journal of Pathology. 159: 431-7. PMID 11485901  0.4
2001 Mende I, Malstrom S, Tsichlis PN, Vogt PK, Aoki M. Oncogenic transformation induced by membrane-targeted Akt2 and Akt3 Oncogene. 20: 4419-4423. PMID 11466625 DOI: 10.1038/sj.onc.1204486  0.4
2001 Patriotis C, Russeva MG, Lin JH, Srinivasula SM, Markova DZ, Tsatsanis C, Makris A, Alnemri ES, Tsichlis PN. Tpl-2 induces apoptosis by promoting the assembly of protein complexes that contain caspase-9, the adapter protein Tvl-1, and procaspase-3 Journal of Cellular Physiology. 187: 176-187. PMID 11267997 DOI: 10.1002/jcp.1066  0.4
2000 Dumitru CD, Ceci JD, Tsatsanis C, Kontoyiannis D, Stamatakis K, Lin JH, Patriotis C, Jenkins NA, Copeland NG, Kollias G, Tsichlis PN. TNF-α induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway Cell. 103: 1071-1083. PMID 11163183 DOI: 10.1016/S0092-8674(00)00210-5  0.4
2000 Poyet JL, Srinivasula SM, Lin JH, Fernandes-Alnemri T, Yamaoka S, Tsichlis PN, Alnemri ES. Activation of the IκB kinases by RIP via IKKγ/NEMO-mediated oligomerization Journal of Biological Chemistry. 275: 37966-37977. PMID 10980203 DOI: 10.1074/jbc.M006643200  0.4
2000 De Vita G, Berlingieri MT, Visconti R, Castellone MD, Viglietto G, Baldassarre G, Zannini M, Bellacosa A, Tsichlis PN, Fusco A, Santoro M. Akt/protein kinase B promotes survival and hormone-independent proliferation of thyroid cells in the absence of dedifferentiating and transforming effects Cancer Research. 60: 3916-3920. PMID 10919669  0.4
2000 De Vita G, Melillo RM, Carlomagno F, Visconti R, Castellone MD, Bellacosa A, Billaud M, Fusco A, Tsichlis PN, Santoro M. Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival. Cancer Research. 60: 3727-31. PMID 10919641  0.4
2000 Kampranis SC, Damianova R, Atallah M, Toby G, Kondi G, Tsichlis PN, Makris AM. A novel plant glutathione S-transferase/peroxidase suppresses Bax lethality in yeast Journal of Biological Chemistry. 275: 29207-29216. PMID 10859306 DOI: 10.1074/jbc.M002359200  0.4
1999 Chan TO, Rittenhouse SE, Tsichlis PN. AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide-dependent phosphorylation Annual Review of Biochemistry. 68: 965-1014. PMID 10872470 DOI: 10.1146/annurev.biochem.68.1.965  0.4
1999 Osada M, Tolkacheva T, Li W, Chan TO, Tsichlis PN, Saez R, Kimmelman AC, Chan AM. Differential roles of Akt, Rac, and Ral in R-Ras-mediated cellular transformation, adhesion, and survival. Molecular and Cellular Biology. 19: 6333-44. PMID 10454580  0.4
1999 Srinivasula SM, Ahmadt M, Lin JH, Poyet JL, Fernandes-Alnemri T, Tsichlis PN, Alnemri ES. CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-κB activation and apoptosis Journal of Biological Chemistry. 274: 17946-17954. PMID 10364242 DOI: 10.1074/jbc.274.25.17946  0.4
1999 Lin JH, Makris A, McMahon C, Bear SE, Patriotis C, Prasad VR, Brent R, Golemis EA, Tsichlis PN. The ankyrin repeat-containing adaptor protein Tvl-1 is a novel substrate and regulator of Raf-1 Journal of Biological Chemistry. 274: 14706-14715. PMID 10329666 DOI: 10.1074/jbc.274.21.14706  0.4
1999 Kurowski TG, Lin Y, Luo Z, Tsichlis PN, Buse MG, Heydrick SJ, Ruderman NB. Hyperglycemia inhibits insulin activation of Akt/protein kinase B but not phosphatidylinositol 3-kinase in rat skeletal muscle. Diabetes. 48: 658-63. PMID 10078574  0.4
1999 Grammatikakis N, Lin JH, Grammatikakis A, Tsichlis PN, Cochran BH. p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function. Molecular and Cellular Biology. 19: 1661-72. PMID 10022854  0.4
1998 Tsatsanis C, Patriotic C, Tsichlis PN. Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-κB Oncogene. 17: 2609-2618. PMID 9840924  0.4
1998 Muise-Helmericks RC, Grimes HL, Bellacosa A, Malstrom SE, Tsichlis PN, Rosen N. Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway. The Journal of Biological Chemistry. 273: 29864-72. PMID 9792703 DOI: 10.1074/jbc.273.45.29864  0.4
1998 Tong B, Grimes HL, Yang TY, Bear SE, Qin Z, Du K, El-Deiry WS, Tsichlis PN. The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation. Molecular and Cellular Biology. 18: 2462-73. PMID 9566867  0.4
1998 Eves EM, Xiong W, Bellacosa A, Kennedy SG, Tsichlis PN, Rosner MR, Hay N. Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line Molecular and Cellular Biology. 18: 2143-2152. PMID 9528786  0.4
1998 Tsatsanis C, Patriotis C, Bear SE, Tsichlis PN. The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines Proceedings of the National Academy of Sciences of the United States of America. 95: 3827-3832. PMID 9520452 DOI: 10.1073/pnas.95.7.3827  0.4
1997 Skorski T, Bellacosa A, Nieborowska-Skorska M, Majewski M, Martinez R, Choi JK, Trotta R, Wlodarski P, Perrotti D, Chan TO, Wasik MA, Tsichlis PN, Calabretta B. Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway Embo Journal. 16: 6151-6161. PMID 9321394 DOI: 10.1093/emboj/16.20.6151  0.4
1997 King WG, Mattaliano MD, Chan TO, Tsichlis PN, Brugge JS. Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation. Molecular and Cellular Biology. 17: 4406-18. PMID 9234699  0.4
1997 Chang HW, Aoki M, Fruman D, Auger KR, Bellacosa A, Tsichlis PN, Cantley LC, Roberts TM, Vogt PK. Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase Science. 276: 1848-1850. PMID 9188528 DOI: 10.1126/science.276.5320.1848  0.4
1997 Ahmed NN, Grimes HL, Bellacosa A, Chan TO, Tsichlis PN. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 3627-32. PMID 9108028 DOI: 10.1073/pnas.94.8.3627  0.4
1997 Kennedy SG, Wagner AJ, Conzen SD, Jordán J, Bellacosa A, Tsichlis PN, Hay N. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal Genes and Development. 11: 701-713. PMID 9087425  0.4
1997 Ceci JD, Patriotis CP, Tsatsanis C, Makris AM, Kovatch R, Swing DA, Jenkins NA, Tsichlis PN, Copeland NG. Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation Genes and Development. 11: 688-700. PMID 9087424  0.4
1996 Grimes HL, Gilks CB, Chan TO, Porter S, Tsichlis PN. The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death. Proceedings of the National Academy of Sciences of the United States of America. 93: 14569-73. PMID 8962093 DOI: 10.1073/pnas.93.25.14569  0.4
1996 Datta K, Bellacosaf A, Chan TO, Tsichlis PN. Akt is a direct target of the phosphatidylinositol 3-kinase: Activation by growth factors, v-src and v-Ha-ras, in Sf9 and mammalian cells Journal of Biological Chemistry. 271: 30835-30839. PMID 8940066 DOI: 10.1074/jbc.271.48.30835  0.4
1996 Grimes HL, Chan TO, Zweidler-McKay PA, Tong B, Tsichlis PN. The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal. Molecular and Cellular Biology. 16: 6263-72. PMID 8887656  0.4
1996 Zweidler-Mckay PA, Grimes HL, Flubacher MM, Tsichlis PN. Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor. Molecular and Cellular Biology. 16: 4024-34. PMID 8754800  0.4
1995 Gilks CB, Porter SD, Barker C, Tsichlis PN, Gout PW. Prolactin (PRL)-dependent expression of a zinc finger protein-encoding gene, Gfi-1, in Nb2 lymphoma cells: Constitutive expression in autonomous sublines Endocrinology. 136: 1805-1808. PMID 7895694  0.4
1995 Datta K, Franke TF, Chan TO, Makris A, Yang SI, Kaplan DR, Morrison DK, Golemis EA, Tsichlis PN. AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation Molecular and Cellular Biology. 15: 2304-2310. PMID 7891724  0.4
1995 Bell DW, Taguchi T, Jenkins NA, Gilbert DJ, Copeland NG, Gilks CB, Zweidler-McKay P, Grimes HL, Tsichlis PN, Testa JR. Chromosomal localization of a gene, GF1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents. Cytogenetics and Cell Genetics. 70: 263-7. PMID 7789186 DOI: 10.1159/000134048  0.4
1995 Franke TF, Yang SI, Chan TO, Datta K, Kazlauskas A, Morrison DK, Kaplan DR, Tsichlis PN. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell. 81: 727-36. PMID 7774014 DOI: 10.1016/0092-8674(95)90534-0  0.4
1994 Franke TF, Tartof KD, Tsichlis PN. The SH2-like Akt homology (AH) domain of c-akt is present in multiple copies in the genome of vertebrate and invertebrate eucaryotes. Cloning and characterization of the Drosophila melanogaster c-akt homolog Dakt1. Oncogene. 9: 141-8. PMID 8302573  0.4
1994 Bellacosa A, Datta K, Bear SE, Patriotis C, Lazo PA, Copeland NG, Jenkins NA, Tsichlis PN. Effects of provirus integration in the Tpl-1/Ets-1 locus in Moloney murine leukemia virus-induced rat T-cell lymphomas: Levels of expression, polyadenylation, transcriptional initiation, and differential splicing of the Ets-1 mRNA Journal of Virology. 68: 2320-2330. PMID 8139017  0.4
1994 Patriotis C, Tsichlis PN. The activated Mlvi-4 locus in moloney murine leukemia virus-induced rat T- cell lymphomas encodes an Env/Mlvi-4 fusion protein Journal of Virology. 68: 7927-7932. PMID 7966583  0.4
1994 Flubacher MM, Bear SE, Tsichlis PN. Replacement of interleukin-2 (IL-2)-generated mitogenic signals by a mink cell focus-forming (MCF) or xenotropic virus-induced IL-9-dependent autocrine loop: Implications for MCF virus-induced leukemogenesis Journal of Virology. 68: 7709-7716. PMID 7966560  0.4
1994 Patriotis C, Makris A, Chernoff J, Tsichlis PN. Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase Proceedings of the National Academy of Sciences of the United States of America. 91: 9755-9759. PMID 7937886 DOI: 10.1073/pnas.91.21.9755  0.4
1993 Ahmed NN, Franke TF, Bellacosa A, Datta K, Gonzalez-Portal ME, Taguchi T, Testa JR, Tsichlis PN. The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential Oncogene. 8: 1957-1963. PMID 8510938  0.4
1993 Makris A, Patriotis C, Bear SE, Tsichlis PN. Genomic organization and expression of Tpl-2 in normal cells and Moloney murine leukemia virus-induced rat T-cell lymphomas: Activation by provirus insertion Journal of Virology. 67: 4283-4289. PMID 8510223  0.4
1993 Gilks CB, Bear SE, Grimes HL, Tsichlis PN. Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein. Molecular and Cellular Biology. 13: 1759-68. PMID 8441411  0.4
1993 Bellacosa A, Franke TF, Gonzalez-Portal ME, Datta K, Taguchi T, Gardner J, Cheng JQ, Testa JR, Tsichlis PN. Structure, expression and chromosomal mapping of c-akt: Relationship to v-akt and its implications Oncogene. 8: 745-754. PMID 8437858  0.4
1993 Makris A, Patriotis C, Bear SE, Tsichlis PN. Structure of a Moloney murine leukemia virus-virus-like 30 recombinant: Implications for transduction of the c-Ha-ras proto-oncogene Journal of Virology. 67: 1286-1291. PMID 8437216  0.4
1993 Taguchi T, Bellacosa A, Zhou JY, Gilbert DJ, Lazo PA, Copeland NG, Jenkins NA, Tsichlis PN, Testa JR. Chromosomal localization of the ox-44 (Cd53) leukocyte antigen gene in man and rodents Cytogenetic and Genome Research. 64: 217-221. PMID 8404042 DOI: 10.1159/000133580  0.4
1993 Barker C, Makris A, Patriotis C, Bear SE, Tsichlis PN. Identification of the gene encoding the mitochondrial elongation factor g in mammals Nucleic Acids Research. 21: 2641-2647. PMID 8332461 DOI: 10.1093/nar/21.11.2641  0.4
1993 Patriotis C, Makris A, Bear SE, Tsichlis PN. Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation Proceedings of the National Academy of Sciences of the United States of America. 90: 2251-2255. PMID 7681591  0.4
1992 Cheng JQ, Godwin AK, Bellacosa A, Taguchi T, Franke TF, Hamilton TC, Tsichlis PN, Testa JR. AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas Proceedings of the National Academy of Sciences of the United States of America. 89: 9267-9271. PMID 1409633  0.4
1992 Barker CS, Bear SE, Keler T, Copeland NG, Gilbert DJ, Jenkins NA, Yeung RS, Tsichlis PN. Activation of the prolactin receptor gene by promoter insertion in a moloney murine leukemia virus-induced rat thymoma Journal of Virology. 66: 6763-6768. PMID 1404614  0.4
1992 Justice MJ, Gilbert DJ, Kinzler KW, Vogelstein B, Buchberg AM, Ceci JD, Matsuda Y, Chapman VM, Patriotis C, Makris A. A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18. Genomics. 13: 1281-8. PMID 1354644 DOI: 10.1016/0888-7543(92)90047-V  0.4
1991 Tsichlis PN, Bear SE. Infection by mink cell focus-forming viruses confers interleukin 2 (IL-2) independence to an IL-2-dependent rat T-cell lymphoma line Proceedings of the National Academy of Sciences of the United States of America. 88: 4611-4615. PMID 2052545  0.4
1991 Bellacosa A, Lazo PA, Bear SE, Tsichlis PN. The Rat Leukocyte Antigen MRC OX-44 Is a Member of a New Family of Cell Surface Proteins Which Appear to Be Involved in Growth Regulation Molecular and Cellular Biology. 11: 2864-2872. PMID 2017181  0.4
1991 Bellacosa A, Testa JR, Staal SP, Tsichlis PN. A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region Science. 254: 274-277. PMID 1833819  0.4
1991 Tsichlis PN, Lazo PA. Virus-host interactions and the pathogenesis of murine and human oncogenic retroviruses Current Topics in Microbiology and Immunology. 171: 96-171. PMID 1667631  0.4
1990 Palumbo AP, Boccadoro M, Battaglio S, Corradini P, Tsichlis PN, Huebner K, Pileri A, Croce CM. Human Homologue of Moloney Leukemia Virus Integration-4 Locus {MLVI-4) Located 20 Kilobases 3′ of the myc Gene, Is Rearranged in Multiple Myelomas Cancer Research. 50: 6478-6482. PMID 2208106  0.4
1990 Lazo PA, Klein-Szanto AJP, Tsichlis PN. T-cell lymphoma lines derived from rat thymomas induced by moloney murine leukemia virus: Phenotypic diversity and its implications Journal of Virology. 64: 3948-3959. PMID 2196385  0.4
1990 Lazo PA, Tsichlis PN. Biology and pathogenesis of retroviruses Seminars in Oncology. 17: 269-294. PMID 2191436  0.4
1990 Tsichlis PN, Lee JS, Bear SE, Lazo PA, Patriotis C, Gustafson E, Shinton S, Jenkins NA, Copeland NG, Huebner K, Croce C, Levan G, Hanson C. Activation of multiple genes by provirus integration in the Mlvi-4 locus in T-cell lymphomas induced by moloney murine leukemia virus Journal of Virology. 64: 2236-2244. PMID 1691313  0.4
1990 Lazo PA, Lee JS, Tsichlis PN. Long-distance activation of the Myc protooncogene by provirus insertion in Mlvi-1 or Mlvi-4 in rat T-cell lymphomas Proceedings of the National Academy of Sciences of the United States of America. 87: 170-173. PMID 1688653 DOI: 10.1073/pnas.87.1.170  0.4
1989 Anagnou NP, Economou-Pachnis A, O'Brien SJ, Modi WS, Nienhuis AW, Tsichlis PN. The human homolog of the moloney leukemia virus integration 2 locus (MLVI2) maps to band p14 of chromosome 5 Genomics. 5: 354-358. PMID 2793187 DOI: 10.1016/0888-7543(89)90069-4  0.4
1989 Bellacosa A, Lazo PA, Bear SE, Shinton S, Tsichlis PN. Induction of multiple independent T-cell lymphomas in rats inoculated with Moloney murine leukemia virus Proceedings of the National Academy of Sciences of the United States of America. 86: 4269-4272. PMID 2786211  0.4
1989 Tsichlis PN, Shepherd BM, Bear SE. Activation of the Mlvi-1/mis-1/pvt-1 locus in Moloney murine leukemia virus-induced T-cell lymphomas Proceedings of the National Academy of Sciences of the United States of America. 86: 5487-5491. PMID 2748599  0.4
1989 Koehne CF, Lazo PA, Alves K, Lee JS, Tsichlis PN, O'Donnell PV. The Mlvi-1 locus involved in the induction of rat T-cell lymphomas and the pvt-1/Mis-1 locus are identical Journal of Virology. 63: 2366-2369. PMID 2704080  0.4
1989 Bear SE, Bellacosa A, Lazo PA, Jenkins NA, Copeland NG, Hanson C, Levan G, Tsichlis PN. Provirus insertion in Tpl-1, an Ets-1-related oncogene, is associated with tumor progression in Moloney murine leukemia virus-induced rat thymic lymphomas Proceedings of the National Academy of Sciences of the United States of America. 86: 7495-7499. PMID 2552446  0.4
1988 Lazo PA, Tsichlis PN. Recombination between two integrated proviruses, one of which was inserted near c-myc in a retrovirus-induced rat thymoma: Implications for tumor progression Journal of Virology. 62: 788-794. PMID 3276924  0.4
1987 Tsichlis PN. Oncogenesis by Moloney murine leukemia virus Anticancer Research. 7: 171-180. PMID 3592629  0.4
1987 Lazo PA, Prasad V, Tsichlis PN. Splice acceptor site for the env message of Moloney murine leukemia virus Journal of Virology. 61: 2038-2041. PMID 3573155  0.4
1987 Bassuk JA, Tsichlis PN, Sorof S. Liver fatty acid binding protein is the mitosis-associated polypeptide target of a carcinogen in rat hepatocytes Proceedings of the National Academy of Sciences of the United States of America. 84: 7547-7551. PMID 3478711  0.4
1986 Furano AV, Somerville CC, Tsichlis PN, D'Ambrosio E. Target sites for the transposition of rat long interspersed repeated DNA elements (LINEs) are not random. Nucleic Acids Research. 14: 3717-27. PMID 3012480 DOI: 10.1093/nar/14.9.3717  0.4
1985 Chang EH, Morgan PL, Lee EJ, Pirollo KF, White EA, Patrick DH, Tsichlis PN. Pathogenicity of retroviruses containing either the normal human c-Ha-ras1 gene or its mutated form derived from the bladder carcinoma EJ/T24 cell line. Journal of Experimental Pathology. 2: 177-89. PMID 3842394  0.4
1985 Economou-Pachnis A, Tsichlis PN. Insertion of an Alu SINE in the human homologue of the Mlvi-2 locus Nucleic Acids Research. 13: 8379-8387. PMID 3001638 DOI: 10.1093/nar/13.23.8379  0.4
1985 Tsichlis PN, Lohse MA, Szpirer C, Levan G. Cellular DNA regions involved in the induction of the rat thymic lymphomas (Mlvi-1, Mlvi-2, Mlvi-3 and c-myc) represent independent loci as determined by their chromosomal map location in the rat Journal of Virology. 56: 938-942. PMID 2999446  0.4
1985 Tsichlis PN, Strauss PG, Lohse MA. Concerted DNA rearrangements in Moloney murine leukemia virus-induced thymomas: A potential synergistic relationship in oncogenesis Journal of Virology. 56: 258-267. PMID 2993654  0.4
1985 Economou-Pachnis A, Lohse MA, Furano AV, Tsichlis PN. Insertion of long interspersed repeated elements at the Igh (immunoglobulin heavy chain) and Mlvi-2 (Moloney leukemia virus integration 2) loci of rats. Proceedings of the National Academy of Sciences of the United States of America. 82: 2857-61. PMID 2986141  0.4
1985 Kozak CA, Strauss PG, Tsichlis PN. Genetic mapping of a cellular DNA region involved in induction of thymic lymphomas (Mlvi-1) to mouse chromosome 15 Molecular and Cellular Biology. 5: 894-897. PMID 2985974  0.4
1985 Shank PR, Schatz PJ, Jensen LM, Tsichlis PN, Coffin JM, Robinson HL. Sequences in the gag-pol-5′env region of avian leukosis viruses confer the ability to induce osteopetrosis Virology. 145: 94-104. PMID 2409672 DOI: 10.1016/0042-6822(85)90204-1  0.4
1984 Tsichlis PN, Strauss PG, Kozak CA. Cellular DNA region involved in induction of thymic lymphomas (Mlvi-2) maps to mouse chromosome 15 Molecular and Cellular Biology. 4: 997-1000. PMID 6328284  0.4
1983 Robinson HL, Coffin JM, Tsichlis PN, Shank PR, Schatz P, Jensen L. Cancer induction by insertional mutagenesis: the role of viral genes in avian leukosis virus induced cancers Progress in Clinical and Biological Research. 119: 37-42. PMID 6306689  0.4
1983 Skalka AM, Tsichlis PN, Malavarca R, Cullen B, Ju G. Viral sequences determining the oncogenicity of avian leukosis viruses Progress in Clinical and Biological Research. 119: 105-118. PMID 6306683  0.4
1983 Coffin JM, Tsichlis PN, Conklin KF, Senior A, Robinson HL. Genomes of endogenous and exogenous avian retroviruses Virology. 126: 51-72. PMID 6302996 DOI: 10.1016/0042-6822(83)90461-0  0.4
1983 Tsichlis PN, Strauss PG, Hu LF. A common region for proviral DNA integration in MoMuLV-induced rat thymic lymphomas Nature. 302: 445-449. PMID 6300684  0.4
1982 Tsichlis PN, Donehower L, Hager G, Zeller N, Malavarca R, Astrin S, Skalka AM. Sequence comparison in the crossover region of an oncogenic avian retrovirus recombinant and its nononcogenic parent: Genetic regions that control growth rate and oncogenic potential Molecular and Cellular Biology. 2: 1331-1338. PMID 6298596  0.4
1982 Robinson HL, Blais BM, Tsichlis PN, Coffin JM. At least two regions of the viral genome determine the oncogenic potential of avian leukosis viruses. Proceedings of the National Academy of Sciences of the United States of America. 79: 1225-9. PMID 6280174  0.4
1981 Coffin JM, Tsichlis PN, Robinson HL. Genetics of leukemogenesis by avian leukosis viruses Hamatologie Und Bluttransfusion. 26: 432-438. PMID 6274756  0.4
1981 Lautenberger JA, Schulz RA, Garon CF, Tsichlis PN, Spyropoulos DD, Pry TW, Rushlow KE, Papas TS. The transforming sequences of avian myelocytomatosis virus (MC29). Journal of Supramolecular Structure and Cellular Biochemistry. 16: 193-207. PMID 6271982 DOI: 10.1002/jsscb.1981.380160209  0.4
1981 Lautenberger JA, Schulz RA, Garon CF, Tsichlis PN, Papas TS. Molecular cloning of avian myelocytomatosis virus (MC29) transforming sequences. Proceedings of the National Academy of Sciences of the United States of America. 78: 1518-22. PMID 6262810 DOI: 10.1073/pnas.78.3.1518  0.4
1980 Green N, Hiai H, Elder JH, Schwartz RS, Khiroya RH, Thomas CY, Tsichlis PN, Coffin JM. Expression of leukemogenic recombinant viruses associated with a recessive gene in HRS/J mice Journal of Experimental Medicine. 152: 249-264. PMID 7400758 DOI: 10.1084/jem.152.2.249  0.4
1980 Coffin JM, Tsichlis PN, Barker CS. Variation in avian retrovirus genomes Annals of the New York Academy of Sciences. 410-425. PMID 6261656 DOI: 10.1111/j.1749-6632.1980.tb27982.x  0.4
1980 Tsichlis PN, Coffin JM. Recombinants between endogenous and exogenous avian tumor viruses: Role of the C region and other portions of the genome in the control of replication and transformation Journal of Virology. 33: 238-249. PMID 6245229  0.4
1980 Tsichlis PN, Conklin KF, Coffin JM. Mutant and recombinant avian retroviruses with extended host range Proceedings of the National Academy of Sciences of the United States of America. 77: 536-540. PMID 6244565  0.4
1980 Bear SE, Tsichlis PN, Schwanz RS. H-2-Mediated resistance to an ecotropic type C retrovirus: Localization of controlling genes and ontogenic studies of resistance Immunogenetics. 11: 451-465. PMID 6101117 DOI: 10.1007/BF01567814  0.4
1980 Andre-Schwartz J, Datta S, Tsichlis PN, Schwartz RS. Type C virus particles in SWR/J mice Biologie Cellulaire. 39: 197-200.  0.4
1979 Robinson HL, Pearson MN, DeSimone DW, Tsichlis PN, Coffin JM. Subgroup-E avian-leukosis-virus-associated disease in chickens Symposia On Quantitative Biology. 44: 1133-1142. PMID 6253188  0.4
1979 Tsichlis PN, Coffin JM. Role of the C region in relative growth rates of endogenous and exogenous avian oncoviruses Symposia On Quantitative Biology. 44: 1123-1132. PMID 6253187  0.4
1979 Andrianakos AA, Tsichlis PN, Merikas EG, Efstratopoulos AD, Sharp JT, Marketos SG, Merikas GE. The effect of glucocorticosteroids on antigen-induced leukocyte migration inhibition Materia Medica Polona. 11: 10-14. PMID 480973  0.4
1979 Tsichlis PN, Coffin JM. Recombination between the defective component of an acute leukemia virus and Rous associated virus 0, an endogenous virus of chickens Proceedings of the National Academy of Sciences of the United States of America. 76: 3001-3005. PMID 223167  0.4
1977 Safran C, Tsichlis PN, Bluming AZ, Desforges JF. Diagnostic planning using computer assisted decision making for patients with Hodgkin's disease Cancer. 39: 2426-2434. PMID 872042  0.4
1977 Safran C, Desforges JF, Tsichlis PN, Bluming AZ. Decision analysis to evaluate lymphangiography in the management of patients with Hodgkin's disease New England Journal of Medicine. 296: 1088-1092. PMID 850519  0.4
1977 Andrianakos AA, Tsichlis PN, Merikas EG, Marketos SG, Sharp JT, Merikas GE. Cell-mediated immunity in systemic lupus erythematosus Clinical and Experimental Immunology. 30: 89-96. PMID 606439  0.4
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