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Pamela L. Schwartzberg - Publications

Biomedical Sciences The George Washington University, Washington, DC, United States 
Immunology, Biochemistry

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Huang B, Gomez-Rodriguez J, Preite S, Garrett LJ, Harper UL, Schwartzberg PL. CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development. Plos One. 11: e0156072. PMID 27258160 DOI: 10.1371/journal.pone.0156072  0.56
2016 Gomez-Rodriguez J, Meylan F, Handon R, Hayes ET, Anderson SM, Kirby MR, Siegel RM, Schwartzberg PL. Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4. Nature Communications. 7: 10857. PMID 26936133 DOI: 10.1038/ncomms10857  0.56
2016 Ruffo E, Malacarne V, Larsen SE, Das R, Patrussi L, Wülfing C, Biskup C, Kapnick SM, Verbist K, Tedrick P, Schwartzberg PL, Baldari CT, Rubio I, Nichols KE, Snow AL, et al. Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1 Science Translational Medicine. 8. DOI: 10.1126/scitranslmed.aad1565  0.56
2015 Wu T, Shin HM, Moseman EA, Ji Y, Huang B, Harly C, Sen JM, Berg LJ, Gattinoni L, McGavern DB, Schwartzberg PL. TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection. Cell Reports. PMID 26365183 DOI: 10.1016/j.celrep.2015.08.049  0.56
2014 Sinai P, Dozmorov IM, Song R, Schwartzberg PL, Wakeland EK, Wülfing C. T/B-cell interactions are more transient in response to weak stimuli in SLE-prone mice. European Journal of Immunology. 44: 3522-31. PMID 25209945 DOI: 10.1002/eji.201444602  0.56
2014 Prince AL, Kraus Z, Carty SA, Ng C, Yin CC, Jordan MS, Schwartzberg PL, Berg LJ. Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathways. Journal of Immunology (Baltimore, Md. : 1950). 193: 688-99. PMID 24943215 DOI: 10.4049/jimmunol.1302059  0.56
2014 Prince AL, Watkin LB, Yin CC, Selin LK, Kang J, Schwartzberg PL, Berg LJ. Innate PLZF+CD4+ αβ T cells develop and expand in the absence of Itk. Journal of Immunology (Baltimore, Md. : 1950). 193: 673-87. PMID 24928994 DOI: 10.4049/jimmunol.1302058  0.56
2014 Tsang JS, Schwartzberg PL, Kotliarov Y, Biancotto A, Xie Z, Germain RN, Wang E, Olnes MJ, Narayanan M, Golding H, Moir S, Dickler HB, Perl S, Cheung F, et al. Global analyses of human immune variation reveal baseline predictors of postvaccination responses. Cell. 157: 499-513. PMID 24725414 DOI: 10.1016/j.cell.2014.03.031  0.56
2014 Gomez-Rodriguez J, Wohlfert EA, Handon R, Meylan F, Wu JZ, Anderson SM, Kirby MR, Belkaid Y, Schwartzberg PL. Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells. The Journal of Experimental Medicine. 211: 529-43. PMID 24534190 DOI: 10.1084/jem.20131459  0.56
2014 Nakayamada S, Poholek AC, Lu KT, Takahashi H, Kato M, Iwata S, Hirahara K, Cannons JL, Schwartzberg PL, Vahedi G, Sun HW, Kanno Y, O'Shea JJ. Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program. Journal of Immunology (Baltimore, Md. : 1950). 192: 2156-66. PMID 24489092 DOI: 10.4049/jimmunol.1300675  0.56
2014 Lucas CL, Kuehn HS, Zhao F, Niemela JE, Deenick EK, Palendira U, Avery DT, Moens L, Cannons JL, Biancalana M, Stoddard J, Ouyang W, Frucht DM, Rao VK, Atkinson TP, ... ... Schwartzberg PL, et al. Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency. Nature Immunology. 15: 88-97. PMID 24165795 DOI: 10.1038/ni.2771  0.56
2013 He J, Tsai LM, Leong YA, Hu X, Ma CS, Chevalier N, Sun X, Vandenberg K, Rockman S, Ding Y, Zhu L, Wei W, Wang C, Karnowski A, Belz GT, ... ... Schwartzberg PL, et al. Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure. Immunity. 39: 770-81. PMID 24138884 DOI: 10.1016/j.immuni.2013.09.007  0.56
2013 Cannons JL, Zhao F, Schwartzberg PL. Ncking BCR-mediated PI3K activation. Embo Reports. 14: 852-3. PMID 23969954 DOI: 10.1038/embor.2013.133  0.56
2013 Dervovic DD, Liang HC, Cannons JL, Elford AR, Mohtashami M, Ohashi PS, Schwartzberg PL, Zúñiga-Pflücker JC. Cellular and molecular requirements for the selection of in vitro-generated CD8 T cells reveal a role for Notch. Journal of Immunology (Baltimore, Md. : 1950). 191: 1704-15. PMID 23851691 DOI: 10.4049/jimmunol.1300417  0.56
2013 Cannons JL, Lu KT, Schwartzberg PL. T follicular helper cell diversity and plasticity. Trends in Immunology. 34: 200-7. PMID 23395212 DOI: 10.1016/  0.56
2013 Dutta M, Kraus ZJ, Gomez-Rodriguez J, Hwang SH, Cannons JL, Cheng J, Lee SY, Wiest DL, Wakeland EK, Schwartzberg PL. A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes. Journal of Immunology (Baltimore, Md. : 1950). 190: 2121-8. PMID 23355739 DOI: 10.4049/jimmunol.1202145  0.56
2012 Qiao Y, Zhu L, Sofi H, Lapinski PE, Horai R, Mueller K, Stritesky GL, He X, Teh HS, Wiest DL, Kappes DJ, King PD, Hogquist KA, Schwartzberg PL, Sant'Angelo DB, et al. Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 16264-9. PMID 22988097 DOI: 10.1073/pnas.1207528109  0.56
2012 Cannons JL, Lu KT, Schwartzberg PL. Lymph node choreography: B cells take the lead. Nature Immunology. 13: 630-2. PMID 22713820 DOI: 10.1038/ni.2349  0.56
2012 Kageyama R, Cannons JL, Zhao F, Yusuf I, Lao C, Locci M, Schwartzberg PL, Crotty S. The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development. Immunity. 36: 986-1002. PMID 22683125 DOI: 10.1016/j.immuni.2012.05.016  0.56
2012 Zhao F, Cannons JL, Dutta M, Griffiths GM, Schwartzberg PL. Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis. Immunity. 36: 1003-16. PMID 22683123 DOI: 10.1016/j.immuni.2012.05.017  0.56
2012 Dutta M, Schwartzberg PL. Characterization of Ly108 in the thymus: evidence for distinct properties of a novel form of Ly108. Journal of Immunology (Baltimore, Md. : 1950). 188: 3031-41. PMID 22393150 DOI: 10.4049/jimmunol.1103226  0.56
2011 Nakayamada S, Kanno Y, Takahashi H, Jankovic D, Lu KT, Johnson TA, Sun HW, Vahedi G, Hakim O, Handon R, Schwartzberg PL, Hager GL, O'Shea JJ. Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity. 35: 919-31. PMID 22195747 DOI: 10.1016/j.immuni.2011.11.012  0.56
2011 Lu KT, Kanno Y, Cannons JL, Handon R, Bible P, Elkahloun AG, Anderson SM, Wei L, Sun H, O'Shea JJ, Schwartzberg PL. Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells. Immunity. 35: 622-32. PMID 22018472 DOI: 10.1016/j.immuni.2011.07.015  0.56
2011 Lindhurst MJ, Sapp JC, Teer JK, Johnston JJ, Finn EM, Peters K, Turner J, Cannons JL, Bick D, Blakemore L, Blumhorst C, Brockmann K, Calder P, Cherman N, Deardorff MA, ... ... Schwartzberg PL, et al. A mosaic activating mutation in AKT1 associated with the Proteus syndrome. The New England Journal of Medicine. 365: 611-9. PMID 21793738 DOI: 10.1056/NEJMoa1104017  0.56
2011 Germain RN, Schwartzberg PL. The human condition: an immunological perspective. Nature Immunology. 12: 369-72. PMID 21502986 DOI: 10.1038/ni0511-369  0.56
2011 Hall JA, Cannons JL, Grainger JR, Dos Santos LM, Hand TW, Naik S, Wohlfert EA, Chou DB, Oldenhove G, Robinson M, Grigg ME, Kastenmayer R, Schwartzberg PL, Belkaid Y. Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha. Immunity. 34: 435-47. PMID 21419664 DOI: 10.1016/j.immuni.2011.03.003  0.56
2011 Gomez-Rodriguez J, Kraus ZJ, Schwartzberg PL. Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fates. The Febs Journal. 278: 1980-9. PMID 21362139 DOI: 10.1111/j.1742-4658.2011.08072.x  0.56
2011 Cannons JL, Tangye SG, Schwartzberg PL. SLAM family receptors and SAP adaptors in immunity. Annual Review of Immunology. 29: 665-705. PMID 21219180 DOI: 10.1146/annurev-immunol-030409-101302  0.56
2011 Zhang S, Readinger JA, DuBois W, Janka-Junttila M, Robinson R, Pruitt M, Bliskovsky V, Wu JZ, Sakakibara K, Patel J, Parent CA, Tessarollo L, Schwartzberg PL, Mock BA. Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production. Blood. 117: 1228-38. PMID 21079150 DOI: 10.1182/blood-2010-05-287821  0.56
2010 Lu KT, Schwartzberg PL. To B or not to B. Blood. 116: 3120-1. PMID 21030566 DOI: 10.1182/blood-2010-08-299222  0.56
2010 Andrés AM, Dennis MY, Kretzschmar WW, Cannons JL, Lee-Lin SQ, Hurle B, Schwartzberg PL, Williamson SH, Bustamante CD, Nielsen R, Clark AG, Green ED. Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation. Plos Genetics. 6: e1001157. PMID 20976248 DOI: 10.1371/journal.pgen.1001157  0.56
2010 Deenick EK, Chan A, Ma CS, Gatto D, Schwartzberg PL, Brink R, Tangye SG. Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling. Immunity. 33: 241-53. PMID 20691615 DOI: 10.1016/j.immuni.2010.07.015  0.56
2010 Cannons JL, Wu JZ, Gomez-Rodriguez J, Zhang J, Dong B, Liu Y, Shaw S, Siminovitch KA, Schwartzberg PL. Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation. Journal of Immunology (Baltimore, Md. : 1950). 185: 2819-27. PMID 20668219 DOI: 10.4049/jimmunol.0902182  0.56
2010 Kuchen S, Resch W, Yamane A, Kuo N, Li Z, Chakraborty T, Wei L, Laurence A, Yasuda T, Peng S, Hu-Li J, Lu K, Dubois W, Kitamura Y, Charles N, ... ... Schwartzberg PL, et al. Regulation of microRNA expression and abundance during lymphopoiesis. Immunity. 32: 828-39. PMID 20605486 DOI: 10.1016/j.immuni.2010.05.009  0.56
2010 Andreotti AH, Schwartzberg PL, Joseph RE, Berg LJ. T-cell signaling regulated by the Tec family kinase, Itk. Cold Spring Harbor Perspectives in Biology. 2: a002287. PMID 20519342 DOI: 10.1101/cshperspect.a002287  0.56
2010 Nikolov NP, Shimizu M, Cleland S, Bailey D, Aoki J, Strom T, Schwartzberg PL, Candotti F, Siegel RM. Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein. Blood. 116: 740-7. PMID 20457871 DOI: 10.1182/blood-2009-08-237560  0.56
2010 Cannons JL, Qi H, Lu KT, Dutta M, Gomez-Rodriguez J, Cheng J, Wakeland EK, Germain RN, Schwartzberg PL. Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84. Immunity. 32: 253-65. PMID 20153220 DOI: 10.1016/j.immuni.2010.01.010  0.56
2009 Gomez-Rodriguez J, Sahu N, Handon R, Davidson TS, Anderson SM, Kirby MR, August A, Schwartzberg PL. Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase. Immunity. 31: 587-97. PMID 19818650 DOI: 10.1016/j.immuni.2009.07.009  0.56
2009 Steinfelder S, Andersen JF, Cannons JL, Feng CG, Joshi M, Dwyer D, Caspar P, Schwartzberg PL, Sher A, Jankovic D. The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). The Journal of Experimental Medicine. 206: 1681-90. PMID 19635859 DOI: 10.1084/jem.20082462  0.56
2009 Rumble JM, Oetjen KA, Stein PL, Schwartzberg PL, Moore BB, Duckett CS. Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP). Cellular Immunology. 259: 82-9. PMID 19595300 DOI: 10.1016/j.cellimm.2009.05.017  0.56
2009 Washington AV, Gibot S, Acevedo I, Gattis J, Quigley L, Feltz R, De La Mota A, Schubert RL, Gomez-Rodriguez J, Cheng J, Dutra A, Pak E, Chertov O, Rivera L, Morales J, ... ... Schwartzberg PL, et al. TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans. The Journal of Clinical Investigation. 119: 1489-501. PMID 19436112 DOI: 10.1172/JCI36175  0.56
2009 Readinger JA, Mueller KL, Venegas AM, Horai R, Schwartzberg PL. Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk. Immunological Reviews. 228: 93-114. PMID 19290923 DOI: 10.1111/j.1600-065X.2008.00757.x  0.56
2009 Linterman MA, Rigby RJ, Wong RK, Yu D, Brink R, Cannons JL, Schwartzberg PL, Cook MC, Walters GD, Vinuesa CG. Follicular helper T cells are required for systemic autoimmunity. The Journal of Experimental Medicine. 206: 561-76. PMID 19221396 DOI: 10.1084/jem.20081886  0.56
2009 Schwartzberg PL, Mueller KL, Qi H, Cannons JL. SLAM receptors and SAP influence lymphocyte interactions, development and function. Nature Reviews. Immunology. 9: 39-46. PMID 19079134 DOI: 10.1038/nri2456  0.56
2009 Goyal R, Bulua AC, Nikolov NP, Schwartzberg PL, Siegel RM. Rheumatologic and autoimmune manifestations of primary immunodeficiency disorders. Current Opinion in Rheumatology. 21: 78-84. PMID 19077721 DOI: 10.1097/BOR.0b013e32831cb939  0.56
2009 Chiang YJ, Jordan MS, Horai R, Schwartzberg PL, Koretzky GA, Hodes RJ. Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation. The Journal of Biological Chemistry. 284: 4429-38. PMID 19074136 DOI: 10.1074/jbc.M808679200  0.56
2008 Chen Q, Cannons JL, Paton JC, Akiba H, Schwartzberg PL, Snapper CM. A novel ICOS-independent, but CD28- and SAP-dependent, pathway of T cell-dependent, polysaccharide-specific humoral immunity in response to intact Streptococcus pneumoniae versus pneumococcal conjugate vaccine. Journal of Immunology (Baltimore, Md. : 1950). 181: 8258-66. PMID 19050242  0.56
2008 Sahu N, Venegas AM, Jankovic D, Mitzner W, Gomez-Rodriguez J, Cannons JL, Sommers C, Love P, Sher A, Schwartzberg PL, August A. Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses. Journal of Immunology (Baltimore, Md. : 1950). 181: 6125-31. PMID 18941202  0.56
2008 Qi H, Cannons JL, Klauschen F, Schwartzberg PL, Germain RN. SAP-controlled T-B cell interactions underlie germinal centre formation. Nature. 455: 764-9. PMID 18843362 DOI: 10.1038/nature07345  0.56
2008 Feng CG, Zheng L, Jankovic D, Báfica A, Cannons JL, Watford WT, Chaussabel D, Hieny S, Caspar P, Schwartzberg PL, Lenardo MJ, Sher A. The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death. Nature Immunology. 9: 1279-87. PMID 18806793 DOI: 10.1038/ni.1653  0.56
2008 Gómez-Rodríguez J, Washington V, Cheng J, Dutra A, Pak E, Liu P, McVicar DW, Schwartzberg PL. Advantages of q-PCR as a method of screening for gene targeting in mammalian cells using conventional and whole BAC-based constructs. Nucleic Acids Research. 36: e117. PMID 18710883 DOI: 10.1093/nar/gkn523  0.56
2008 Readinger JA, Schiralli GM, Jiang JK, Thomas CJ, August A, Henderson AJ, Schwartzberg PL. Selective targeting of ITK blocks multiple steps of HIV replication. Proceedings of the National Academy of Sciences of the United States of America. 105: 6684-9. PMID 18443296 DOI: 10.1073/pnas.0709659105  0.56
2007 Horai R, Mueller KL, Handon RA, Cannons JL, Anderson SM, Kirby MR, Schwartzberg PL. Requirements for selection of conventional and innate T lymphocyte lineages. Immunity. 27: 775-85. PMID 18031697 DOI: 10.1016/j.immuni.2007.09.012  0.56
2007 Gomez-Rodriguez J, Readinger JA, Viorritto IC, Mueller KL, Houghtling RA, Schwartzberg PL. Tec kinases, actin, and cell adhesion. Immunological Reviews. 218: 45-64. PMID 17624943 DOI: 10.1111/j.1600-065X.2007.00534.x  0.56
2007 Adriani M, Aoki J, Horai R, Thornton AM, Konno A, Kirby M, Anderson SM, Siegel RM, Candotti F, Schwartzberg PL. Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome. Clinical Immunology (Orlando, Fla.). 124: 41-8. PMID 17512803 DOI: 10.1016/j.clim.2007.02.001  0.56
2007 Schwartzberg PL. Formin the way. Immunity. 26: 139-41. PMID 17307700 DOI: 10.1016/j.immuni.2007.02.007  0.56
2007 Kim IJ, Burkum CE, Cookenham T, Schwartzberg PL, Woodland DL, Blackman MA. Perturbation of B cell activation in SLAM-associated protein-deficient mice is associated with changes in gammaherpesvirus latency reservoirs. Journal of Immunology (Baltimore, Md. : 1950). 178: 1692-701. PMID 17237419  0.56
2007 Konno A, Kirby M, Anderson SA, Schwartzberg PL, Candotti F. The expression of Wiskott-Aldrich syndrome protein (WASP) is dependent on WASP-interacting protein (WIP). International Immunology. 19: 185-92. PMID 17205972 DOI: 10.1093/intimm/dxl135  0.56
2007 Zhao L, Cannons JL, Anderson S, Kirby M, Xu L, Castilla LH, Schwartzberg PL, Bosselut R, Liu PP. CBFB-MYH11 hinders early T-cell development and induces massive cell death in the thymus. Blood. 109: 3432-40. PMID 17185462 DOI: 10.1182/blood-2006-10-051508  0.56
2006 Lindhurst MJ, Fiermonte G, Song S, Struys E, De Leonardis F, Schwartzberg PL, Chen A, Castegna A, Verhoeven N, Mathews CK, Palmieri F, Biesecker LG. Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia. Proceedings of the National Academy of Sciences of the United States of America. 103: 15927-32. PMID 17035501 DOI: 10.1073/pnas.0607661103  0.56
2006 Kamperschroer C, Dibble JP, Meents DL, Schwartzberg PL, Swain SL. SAP is required for Th cell function and for immunity to influenza. Journal of Immunology (Baltimore, Md. : 1950). 177: 5317-27. PMID 17015717  0.56
2006 Broussard C, Fleischacker C, Fleischecker C, Horai R, Chetana M, Venegas AM, Sharp LL, Hedrick SM, Fowlkes BJ, Schwartzberg PL. Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk. Immunity. 25: 93-104. PMID 16860760 DOI: 10.1016/j.immuni.2006.05.011  0.56
2006 Cannons JL, Yu LJ, Jankovic D, Crotty S, Horai R, Kirby M, Anderson S, Cheever AW, Sher A, Schwartzberg PL. SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation. The Journal of Experimental Medicine. 203: 1551-65. PMID 16754717 DOI: 10.1084/jem.20052097  0.56
2006 Jordan MS, Sadler J, Austin JE, Finkelstein LD, Singer AL, Schwartzberg PL, Koretzky GA. Functional hierarchy of the N-terminal tyrosines of SLP-76. Journal of Immunology (Baltimore, Md. : 1950). 176: 2430-8. PMID 16456002  0.56
2006 Broussard C, Fleischacker C, Horai R, Chetana M, Venegas AM, Sharp LL, Hedrick SM, Fowlkes BJ, Schwartzberg PL. Altered Development of CD8+ T Cell Lineages in Mice Deficient for the Tec Kinases Itk and Rlk (DOI:10.1016/j.immuni.2006.05.011) Immunity. 25: 849. DOI: 10.1016/j.immuni.2006.10.009  0.56
2005 Finkelstein LD, Shimizu Y, Schwartzberg PL. Tec kinases regulate TCR-mediated recruitment of signaling molecules and integrin-dependent cell adhesion. Journal of Immunology (Baltimore, Md. : 1950). 175: 5923-30. PMID 16237085  0.56
2005 Loftus SK, Cannons JL, Incao A, Pak E, Chen A, Zerfas PM, Bryant MA, Biesecker LG, Schwartzberg PL, Pavan WJ. Acinar cell apoptosis in Serpini2-deficient mice models pancreatic insufficiency. Plos Genetics. 1: e38. PMID 16184191 DOI: 10.1371/journal.pgen.0010038  0.56
2005 Schwartzberg PL, Finkelstein LD, Readinger JA. TEC-family kinases: regulators of T-helper-cell differentiation. Nature Reviews. Immunology. 5: 284-95. PMID 15803148 DOI: 10.1038/nri1591  0.56
2005 Berg LJ, Finkelstein LD, Lucas JA, Schwartzberg PL. Tec family kinases in T lymphocyte development and function. Annual Review of Immunology. 23: 549-600. PMID 15771581 DOI: 10.1146/annurev.immunol.22.012703.104743  0.56
2005 Nichols KE, Hom J, Gong SY, Ganguly A, Ma CS, Cannons JL, Tangye SG, Schwartzberg PL, Koretzky GA, Stein PL. Regulation of NKT cell development by SAP, the protein defective in XLP. Nature Medicine. 11: 340-5. PMID 15711562 DOI: 10.1038/nm1189  0.56
2005 Hwang ES, Szabo SJ, Schwartzberg PL, Glimcher LH. T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3. Science (New York, N.Y.). 307: 430-3. PMID 15662016 DOI: 10.1126/science.1103336  0.56
2005 Dombroski D, Houghtling RA, Labno CM, Precht P, Takesono A, Caplen NJ, Billadeau DD, Wange RL, Burkhardt JK, Schwartzberg PL. Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton. Journal of Immunology (Baltimore, Md. : 1950). 174: 1385-92. PMID 15661896  0.56
2005 Nichols KE, Ma CS, Cannons JL, Schwartzberg PL, Tangye SG. Molecular and cellular pathogenesis of X-linked lymphoproliferative disease. Immunological Reviews. 203: 180-99. PMID 15661030 DOI: 10.1111/j.0105-2896.2005.00230.x  0.56
2004 Horai R, Nakajima A, Habiro K, Kotani M, Nakae S, Matsuki T, Nambu A, Saijo S, Kotaki H, Sudo K, Okahara A, Tanioka H, Ikuse T, Ishii N, Schwartzberg PL, et al. TNF-alpha is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice. The Journal of Clinical Investigation. 114: 1603-11. PMID 15578092 DOI: 10.1172/JCI20742  0.56
2004 Cannons JL, Yu LJ, Hill B, Mijares LA, Dombroski D, Nichols KE, Antonellis A, Koretzky GA, Gardner K, Schwartzberg PL. SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1. Immunity. 21: 693-706. PMID 15539155 DOI: 10.1016/j.immuni.2004.09.012  0.56
2004 Mooney JM, Klem J, Wülfing C, Mijares LA, Schwartzberg PL, Bennett M, Schatzle JD. The murine NK receptor 2B4 (CD244) exhibits inhibitory function independent of signaling lymphocytic activation molecule-associated protein expression. Journal of Immunology (Baltimore, Md. : 1950). 173: 3953-61. PMID 15356144  0.56
2004 Finkelstein LD, Schwartzberg PL. Tec kinases: shaping T-cell activation through actin. Trends in Cell Biology. 14: 443-51. PMID 15308211 DOI: 10.1016/j.tcb.2003.07.001  0.56
2004 Hron JD, Caplan L, Gerth AJ, Schwartzberg PL, Peng SL. SH2D1A regulates T-dependent humoral autoimmunity. The Journal of Experimental Medicine. 200: 261-6. PMID 15263031 DOI: 10.1084/jem.20040526  0.56
2004 Al-Shami A, Spolski R, Kelly J, Fry T, Schwartzberg PL, Pandey A, Mackall CL, Leonard WJ. A role for thymic stromal lymphopoietin in CD4(+) T cell development. The Journal of Experimental Medicine. 200: 159-68. PMID 15263024 DOI: 10.1084/jem.20031975  0.56
2004 Sood R, Bader PI, Speer MC, Edwards YH, Eddings EM, Blair RT, Hu P, Faruque MU, Robbins CM, Zhang H, Leuders J, Morrison K, Thompson D, Schwartzberg PL, Meltzer PS, et al. Cloning and characterization of an inversion breakpoint at 6q23.3 suggests a role for Map7 in sacral dysgenesis. Cytogenetic and Genome Research. 106: 61-7. PMID 15218243 DOI: 10.1159/000078563  0.56
2004 Takesono A, Horai R, Mandai M, Dombroski D, Schwartzberg PL. Requirement for Tec kinases in chemokine-induced migration and activation of Cdc42 and Rac. Current Biology : Cb. 14: 917-22. PMID 15186750 DOI: 10.1016/j.cub.2004.04.011  0.56
2004 Cheng J, Dutra A, Takesono A, Garrett-Beal L, Schwartzberg PL. Improved generation of C57BL/6J mouse embryonic stem cells in a defined serum-free media. Genesis (New York, N.Y. : 2000). 39: 100-4. PMID 15170695 DOI: 10.1002/gene.20031  0.56
2004 Cannons JL, Schwartzberg PL. Fine-tuning lymphocyte regulation: what's new with tyrosine kinases and phosphatases? Current Opinion in Immunology. 16: 296-303. PMID 15134778 DOI: 10.1016/j.coi.2004.03.011  0.56
2003 Schwartzberg PL. Amplifying Btk's signal. Immunity. 19: 634-6. PMID 14614849 DOI: 10.1016/S1074-7613(03)00304-2  0.56
2003 Labno CM, Lewis CM, You D, Leung DW, Takesono A, Kamberos N, Seth A, Finkelstein LD, Rosen MK, Schwartzberg PL, Burkhardt JK. Itk functions to control actin polymerization at the immune synapse through localized activation of Cdc42 and WASP Current Biology. 13: 1619-1624. PMID 13678593 DOI: 10.1016/j.cub.2003.08.005  0.56
2003 Schwartzberg PL. Genetic approaches to tyrosine kinase signaling pathways in the immune system. Immunologic Research. 27: 481-8. PMID 12857991 DOI: 10.1385/IR:27:2-3:481  0.56
2003 Latour S, Roncagalli R, Chen R, Bakinowski M, Shi X, Schwartzberg PL, Davidson D, Veillette A. Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation. Nature Cell Biology. 5: 149-54. PMID 12545173 DOI: 10.1038/ncb919  0.56
2003 Crotty S, Kersh EN, Cannons J, Schwartzberg PL, Ahmed R. SAP is required for generating long-term humoral immunity. Nature. 421: 282-7. PMID 12529646 DOI: 10.1038/nature01318  0.56
2002 Ozaki K, Spolski R, Feng CG, Qi CF, Cheng J, Sher A, Morse HC, Liu C, Schwartzberg PL, Leonard WJ. A critical role for IL-21 in regulating immunoglobulin production. Science (New York, N.Y.). 298: 1630-4. PMID 12446913 DOI: 10.1126/science.1077002  0.56
2002 Takesono A, Finkelstein LD, Schwartzberg PL. Beyond calcium: new signaling pathways for Tec family kinases. Journal of Cell Science. 115: 3039-48. PMID 12118060  0.56
2002 Makrigiannis AP, Pau AT, Schwartzberg PL, McVicar DW, Beck TW, Anderson SK. A BAC contig map of the Ly49 gene cluster in 129 mice reveals extensive differences in gene content relative to C57BL/6 mice. Genomics. 79: 437-44. PMID 11863373 DOI: 10.1006/geno.2002.6724  0.56
2001 Czar MJ, Debnath J, Schaeffer EM, Lewis CM, Schwartzberg PL. Biochemical and genetic analyses of the Tec kinases Itk and Rlk/Txk Biochemical Society Transactions. 29: 863-867. PMID 11709089 DOI: 10.1042/0300-5127:0290863  0.56
2001 Schaeffer EM, Yap GS, Lewis CM, Czar MJ, McVicar DW, Cheever AW, Sher A, Schwartzberg PL. Mutation of Tec family kinases alters T helper cell differentiation. Nature Immunology. 2: 1183-8. PMID 11702066 DOI: 10.1038/ni734  0.56
2001 Schwartzberg PL. Immunology: Tampering with the immune system Science. 293: 228-229. PMID 11452106 DOI: 10.1126/science.1063291  0.56
2001 Czar MJ, Schwartzberg PL. XLP: One gene, many players Clinical Immunology. 100: 2-3. PMID 11414739 DOI: 10.1006/clim.2001.5051  0.56
2001 Lewis CM, Broussard C, Czar MJ, Schwartzberg PL. Tec kinases: Modulators of lymphocyte signaling and development Current Opinion in Immunology. 13: 317-325. PMID 11406363 DOI: 10.1016/S0952-7915(00)00221-1  0.56
2001 Czar MJ, Kersh EN, Mijares LA, Lanier G, Lewis J, Yap G, Chen A, Sher A, Duckett CS, Ahmed R, Schwartzberg PL. Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP Proceedings of the National Academy of Sciences of the United States of America. 98: 7449-7454. PMID 11404475 DOI: 10.1073/pnas.131193098  0.56
2001 Chamorro M, Czar MJ, Debnath J, Cheng G, Lenardo MJ, Varmus HE, Schwartzberg PL. Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk. Bmc Immunology. 2: 3. PMID 11353545 DOI: 10.1186/1471-2172-2-3  0.56
2001 Xing L, Venegas AM, Chen A, Garrett-Beal L, Boyce BF, Varmus HE, Schwartzberg PL. Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival. Genes & Development. 15: 241-53. PMID 11157779 DOI: 10.1101/gad.840301  0.56
2001 Ellis CE, Schwartzberg PL, Grider TL, Fink DW, Nussbaum RL. α-Synuclein Is Phosphorylated by Members of the Src Family of Protein-tyrosine Kinases Journal of Biological Chemistry. 276: 3879-3884. PMID 11078745 DOI: 10.1074/jbc.M010316200  0.56
2000 Wagner KU, Claudio E, Rucker EB, Riedlinger G, Broussard C, Schwartzberg PL, Siebenlist U, Hennighausen L. Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly. Development (Cambridge, England). 127: 4949-58. PMID 11044408  0.56
2000 Schaeffer EM, Broussard C, Debnath J, Anderson S, McVicar DW, Schwartzberg PL. Tec family kinases modulate thresholds for thymocyte development and selection Journal of Experimental Medicine. 192: 987-1000. PMID 11015440 DOI: 10.1084/jem.192.7.987  0.56
2000 Shan X, Czar MJ, Bunnell SC, Liu P, Liu Y, Schwartzberg PL, Wange RL. Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Molecular and Cellular Biology. 20: 6945-57. PMID 10958690 DOI: 10.1128/MCB.20.18.6945-6957.2000  0.56
2000 Schaeffer EM, Schwartzberg PL. Tec family kinases in lymphocyte signaling and function Current Opinion in Immunology. 12: 282-288. PMID 10781397 DOI: 10.1016/S0952-7915(00)00088-1  0.56
2000 Sun Z, Arendt CW, Ellmeier W, Schaeffer EM, Sunshine MJ, Gandhi L, Annes J, Petrzilka D, Kupfer A, Schwartzberg PL, Littman DR. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. Nature. 404: 402-7. PMID 10746729 DOI: 10.1038/35006090  0.56
1999 Eliceiri BP, Paul R, Schwartzberg PL, Hood JD, Leng J, Cheresh DA. Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability Molecular Cell. 4: 915-924. PMID 10635317  0.56
1999 Felsenfeld DP, Schwartzberg PL, Venegas A, Tse R, Sheetz MP. Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src. Nature Cell Biology. 1: 200-6. PMID 10559917 DOI: 10.1038/12021  0.56
1999 Schwartzberg PL. A friendly signal Nature Genetics. 23: 128-130. PMID 10508499 DOI: 10.1038/13753  0.56
1999 Schaeffer EM, Debnath J, Yap G, McVicar D, Liao XC, Littman DR, Sher A, Varmus HE, Lenardo MJ, Schwartzberg PL. Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science (New York, N.Y.). 284: 638-41. PMID 10213685 DOI: 10.1126/science.284.5414.638  0.56
1999 Debnath J, Chamorro M, Czar MJ, Schaeffer EM, Lenardo MJ, Varmus HE, Schwartzberg PL. rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases. Molecular and Cellular Biology. 19: 1498-507. PMID 9891083  0.56
1998 Schneider H, Schwartzberg PL, Rudd CE. Resting lymphocyte kinase (RIk/Txk) phosphorylates the YVKM motif and regulates PI 3-kinase binding to T-Cell antigen CTLA-4 Biochemical and Biophysical Research Communications. 252: 14-19. PMID 9813138 DOI: 10.1006/bbrc.1998.9559  0.56
1998 Schwartzberg PL. The many faces of Src: Multiple functions of a prototypical tyrosine kinase Oncogene. 17: 1463-1468. PMID 9779992  0.56
1997 Schwartzberg PL, Xing L, Hoffmann O, Lowell CA, Garrett L, Boyce BF, Varmus HE. Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice. Genes & Development. 11: 2835-44. PMID 9353253  0.56
1995 Hu Q, Davidson D, Schwartzberg PL, Macchiarini F, Lenardo MJ, Bluestone JA, Matis LA. Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage Journal of Biological Chemistry. 270: 1928-1934. PMID 7829530 DOI: 10.1074/jbc.270.4.1928  0.56
1995 Hardin JD, Boast S, Schwartzberg PL, Lee G, Alt FW, Stall AM, Goff SP. Bone marrow B lymphocyte development in c-abl-deficient mice. Cellular Immunology. 165: 44-54. PMID 7671324 DOI: 10.1006/cimm.1995.1185  0.56
1994 Zúñiga-Pflücker JC, Jiang D, Schwartzberg PL, Lenardo MJ. Sublethal γ-radiation induces differentiation of CD4-/CD8- into CD4+/CD8+ thymocytes without T cell receptor β rearrangement in recombinase activation gene 2-/- mice Journal of Experimental Medicine. 180: 1517-1521. PMID 7931082  0.56
1993 Schwartzberg PL, Roth MJ, Tanese N, Goff SP. Analysis of a temperature-sensitive mutation affecting the integration protein of Moloney murine leukemia virus. Virology. 192: 673-8. PMID 8421906 DOI: 10.1006/viro.1993.1086  0.56
1991 Schwartzberg PL, Stall AM, Hardin JD, Bowdish KS, Humaran T, Boast S, Harbison ML, Robertson EJ, Goff SP. Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations Cell. 65: 1165-1175. PMID 2065353  0.56
1990 Schwartzberg PL, Robertson EJ, Goff SP. Targeted gene disruption of the endogenous c-abl locus by homologous recombination with DNA encoding a selectable fusion protein Proceedings of the National Academy of Sciences of the United States of America. 87: 3210-3214. PMID 2183226  0.56
1989 Schwartzberg PL, Goff SP, Robertson EJ. Germ-like transmission of a c-abl mutation produced by targeted gene disruption in ES cells Science. 246: 799-803. PMID 2554496  0.56
1989 Roth MJ, Schwartzberg PL, Goff SP. Structure of the termini of DNA intermediates in the integration of retroviral DNA: Dependence on IN function and terminal DNA sequence Cell. 58: 47-54. PMID 2546673 DOI: 10.1016/0092-8674(89)90401-7  0.56
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