Youngjae You - Publications

Affiliations: 
Department of Chemistry and Biochemistry University of Oklahoma, Norman, OK, United States 
Area:
General Chemistry, Pharmaceutical Chemistry, Pharmacy

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Li M, Nguyen L, Subramaniyan B, Bio M, Peer CJ, Kendrick J, Figg WD, Woo S, You Y. PBPK modeling-based optimization of site-specific chemo-photodynamic therapy with far-red light-activatable paclitaxel prodrug. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31299262 DOI: 10.1016/j.jconrel.2019.07.010  0.84
2019 Bio M, Mahabubur KM, Lim I, Rajaputra P, Hurst RE, You Y. Singlet oxygen-activatable Paclitaxel prodrugs via intermolecular activation for combined PDT and chemotherapy. Bioorganic & Medicinal Chemistry Letters. PMID 30987891 DOI: 10.1016/j.bmcl.2019.03.053  0.92
2017 Thapa P, Li M, Karki R, Bio M, Rajaputra P, Nkepang G, Woo S, You Y. Folate-PEG Conjugates of a Far-Red Light-Activatable Paclitaxel Prodrug to Improve Selectivity toward Folate Receptor-Positive Cancer Cells. Acs Omega. 2: 6349-6360. PMID 29104951 DOI: 10.1021/acsomega.7b01105  0.92
2017 Li M, Thapa P, Rajaputra P, Bio M, Peer CJ, Figg WD, You Y, Woo S. Quantitative modeling of the dynamics and intracellular trafficking of far-red light-activatable prodrugs: implications in stimuli-responsive drug delivery system. Journal of Pharmacokinetics and Pharmacodynamics. PMID 28913666 DOI: 10.1007/s10928-017-9543-z  0.92
2017 Bio M, Rajaputra P, Lim I, Thapa P, Tienabeso B, Hurst RE, You Y. Efficient activation of a visible light-activatable CA4 prodrug through intermolecular photo-unclick chemistry in mitochondria. Chemical Communications (Cambridge, England). PMID 28111669 DOI: 10.1039/c6cc09994g  0.92
2016 Thapa P, Li M, Bio M, Rajaputra P, Nkepang G, Sun Y, Woo S, You Y. Far-red Light-activatable Prodrug of Paclitaxel for the Combined Effects of Photodynamic Therapy and Site-specific Paclitaxel Chemotherapy. Journal of Medicinal Chemistry. PMID 26974508 DOI: 10.1021/acs.jmedchem.5b01971  0.92
2016 Rajaputra P, Bio M, Nkepang G, Thapa P, Woo S, You Y. Anticancer drug released from near IR-activated prodrug overcomes spatiotemporal limits of singlet oxygen. Bioorganic & Medicinal Chemistry. PMID 26928287 DOI: 10.1016/j.bmc.2016.02.025  0.92
2015 Bio M, Rajaputra P, You Y. Photodynamic therapy via FRET following bioorthogonal click reaction in cancer cells. Bioorganic & Medicinal Chemistry Letters. PMID 26584884 DOI: 10.1016/j.bmcl.2015.11.014  0.68
2015 Hurst RE, Hauser PJ, You Y, Bailey-Downs LC, Bastian A, Matthews SM, Thorpe J, Earle C, Bourguignon LY, Ihnat MA. Identification of novel drugs to target dormant micrometastases. Bmc Cancer. 15: 404. PMID 25971923 DOI: 10.1186/s12885-015-1409-4  0.92
2015 Watley RL, Awuah SG, Bio M, Cantu R, Gobeze HB, Nesterov VN, Das SK, D'Souza F, You Y. Dual Functioning Thieno-Pyrrole Fused BODIPY Dyes for NIR Optical Imaging and Photodynamic Therapy: Singlet Oxygen Generation without Heavy Halogen Atom Assistance. Chemistry, An Asian Journal. 10: 1335-43. PMID 25779683 DOI: 10.1002/asia.201500140  0.92
2014 Nkepang G, Bio M, Rajaputra P, Awuah SG, You Y. Folate receptor-mediated enhanced and specific delivery of far-red light-activatable prodrugs of combretastatin A-4 to FR-positive tumor. Bioconjugate Chemistry. 25: 2175-88. PMID 25351441 DOI: 10.1021/bc500376j  0.92
2014 Muli DK, Rajaputra P, You Y, McGrath DV. Asymmetric ZnPc-rhodamine B conjugates for mitochondrial targeted photodynamic therapy. Bioorganic & Medicinal Chemistry Letters. 24: 4496-500. PMID 25150377 DOI: 10.1016/j.bmcl.2014.07.082  0.92
2014 Bandi V, Das SK, Awuah SG, You Y, D'Souza F. Thieno-pyrrole-fused 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-fullerene dyads: utilization of near-infrared sensitizers for ultrafast charge separation in donor-acceptor systems. Journal of the American Chemical Society. 136: 7571-4. PMID 24820034 DOI: 10.1021/ja503015f  0.92
2014 Bio M, Rajaputra P, Nkepang G, You Y. Far-red light activatable, multifunctional prodrug for fluorescence optical imaging and combinational treatment. Journal of Medicinal Chemistry. 57: 3401-9. PMID 24694092 DOI: 10.1021/jm5000722  0.92
2013 Hossion AM, Bio M, Nkepang G, Awuah SG, You Y. Visible Light Controlled Release of Anticancer Drug through Double Activation of Prodrug. Acs Medicinal Chemistry Letters. 4: 124-7. PMID 24900573 DOI: 10.1021/ml3003617  0.92
2013 Awuah SG, Das SK, D'Souza F, You Y. Thieno-pyrrole-fused BODIPY intermediate as a platform to multifunctional NIR agents. Chemistry, An Asian Journal. 8: 3123-32. PMID 24038940 DOI: 10.1002/asia.201300855  0.92
2013 Bio M, Rajaputra P, Nkepang G, Awuah SG, Hossion AML, You Y. Site-specific and far-red-light-activatable prodrug of combretastatin A-4 using photo-unclick chemistry Journal of Medicinal Chemistry. 56: 3936-3942. PMID 23631389 DOI: 10.1021/jm400139w  0.92
2013 Ngen EJ, Xiao L, Rajaputra P, Yan X, You Y. Enhanced singlet oxygen generation from a porphyrin-rhodamine B dyad by two-photon excitation through resonance energy transfer. Photochemistry and Photobiology. 89: 841-8. PMID 23489066 DOI: 10.1111/php.12071  0.92
2013 Rajaputra P, Nkepang G, Watley R, You Y. Synthesis and in vitro biological evaluation of lipophilic cation conjugated photosensitizers for targeting mitochondria. Bioorganic & Medicinal Chemistry. 21: 379-87. PMID 23245573 DOI: 10.1016/j.bmc.2012.11.032  0.92
2012 Bio M, Nkepang G, You Y. Click and photo-unclick chemistry of aminoacrylate for visible light-triggered drug release Chemical Communications. 48: 6517-6519. PMID 22622787 DOI: 10.1039/c2cc32373g  0.92
2012 Nkepang G, Pogula PK, Bio M, You Y. Synthesis and singlet oxygen reactivity of 1,2-diaryloxyethenes and selected sulfur and nitrogen analogs Photochemistry and Photobiology. 88: 753-759. PMID 22268454 DOI: 10.1111/j.1751-1097.2012.01095.x  0.92
2011 Paul B, Rajaputra P, You Y. In vitro and in vivo photodynamic activity of core-modified porphyrin IY69 using 690 nm diode laser. Photochemistry and Photobiology. 87: 1468-73. PMID 21854396 DOI: 10.1111/j.1751-1097.2011.00988.x  0.92
2011 Awuah SG, Polreis J, Biradar V, You Y. Singlet oxygen generation by novel NIR BODIPY dyes. Organic Letters. 13: 3884-7. PMID 21732590 DOI: 10.1021/ol2014076  0.92
2009 Ngen EJ, Rajaputra P, You Y. Evaluation of delocalized lipophilic cationic dyes as delivery vehicles for photosensitizers to mitochondria. Bioorganic & Medicinal Chemistry. 17: 6631-40. PMID 19692249 DOI: 10.1016/j.bmc.2009.07.074  0.92
2008 Ngen EJ, Daniels TS, Murthy RS, Detty MR, You Y. Core-modified porphyrins. Part 6: Effects of lipophilicity and core structures on physicochemical and biological properties in vitro. Bioorganic & Medicinal Chemistry. 16: 3171-83. PMID 18164203 DOI: 10.1016/j.bmc.2007.12.023  0.92
2007 Chintharlapalli S, Papineni S, Liu S, Jutooru I, Chadalapaka G, Cho SD, Murthy RS, You Y, Safe S. 2-cyano-lup-1-en-3-oxo-20-oic acid, a cyano derivative of betulinic acid, activates peroxisome proliferator-activated receptor gamma in colon and pancreatic cancer cells. Carcinogenesis. 28: 2337-46. PMID 17724373 DOI: 10.1093/carcin/bgm189  0.92
2006 You Y, Gibson SL, Detty MR. Phototoxicity of a core-modified porphyrin and induction of apoptosis. Journal of Photochemistry and Photobiology. B, Biology. 85: 155-62. PMID 16905327 DOI: 10.1016/j.jphotobiol.2006.07.002  0.92
2006 Tombline G, Donnelly DJ, Holt JJ, You Y, Ye M, Gannon MK, Nygren CL, Detty MR. Stimulation of P-glycoprotein ATPase by analogues of tetramethylrosamine: coupling of drug binding at the "R" site to the ATP hydrolysis transition state. Biochemistry. 45: 8034-47. PMID 16800628 DOI: 10.1021/bi0603470  0.92
2005 You Y, Gibson SL, Detty MR. Core-modified porphyrins. Part 5: Electronic effects on photophysical and biological properties in vitro. Bioorganic & Medicinal Chemistry. 13: 5968-80. PMID 16084729 DOI: 10.1016/j.bmc.2005.07.006  0.92
2005 Gibson SL, Holt JJ, Ye M, Donnelly DJ, Ohulchanskyy TY, You Y, Detty MR. Structure-activity studies of uptake and phototoxicity with heavy-chalcogen analogues of tetramethylrosamine in vitro in chemosensitive and multidrug-resistant cells. Bioorganic & Medicinal Chemistry. 13: 6394-403. PMID 16084725 DOI: 10.1016/j.bmc.2005.06.056  0.92
2005 You Y. Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents. Current Pharmaceutical Design. 11: 1695-717. PMID 15892669 DOI: 10.2174/1381612053764724  0.92
2005 You Y, Gibson SL, Hilf R, Ohulchanskyy TY, Detty MR. Core-modified porphyrins. Part 4: Steric effects on photophysical and biological properties in vitro. Bioorganic & Medicinal Chemistry. 13: 2235-51. PMID 15727875 DOI: 10.1016/j.bmc.2004.12.048  0.92
2003 You Y, Gibson SL, Hilf R, Davies SR, Oseroff AR, Roy I, Ohulchanskyy TY, Bergey EJ, Detty MR. Water soluble, core-modified porphyrins. 3. Synthesis, photophysical properties, and in vitro studies of photosensitization, uptake, and localization with carboxylic acid-substituted derivatives. Journal of Medicinal Chemistry. 46: 3734-47. PMID 12904078 DOI: 10.1021/jm030136i  0.92
2003 You Y, Ahsan K, Detty MR. Mechanistic studies of the tellurium(II)/tellurium(IV) redox cycle in thiol peroxidase-like reactions of diorganotellurides in methanol. Journal of the American Chemical Society. 125: 4918-27. PMID 12696911 DOI: 10.1021/ja029590m  0.92
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