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Lai-Chu Wu - Publications

Biochemistry Ohio State University, Columbus, Columbus, OH 
Biochemistry, Immunology

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Wang Y, Chu J, Yi P, Dong W, Saultz JN, Wang Y, Wang H, Scoville SD, Zhang J, Wu LC, Deng Y, He X, Mundy-Bosse BL, Freud AG, Wang LS, et al. SMAD4 promotes TGF-β-independent NK cell homeostasis and maturation and antitumor immunity. The Journal of Clinical Investigation. PMID 30183689 DOI: 10.1172/JCI121227  0.48
2017 Victor AR, Nalin AP, Dong W, McClory S, Wei M, Mao C, Kladney RD, Youssef Y, Chan WK, Briercheck EL, Hughes T, Scoville SD, Pitarresi JR, Chen C, Manz S, ... Wu LC, et al. IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-κB. Journal of Immunology (Baltimore, Md. : 1950). PMID 28842466 DOI: 10.4049/jimmunol.1601554  0.48
2017 Shen N, Yan F, Pang J, Zhao N, Gangat N, Wu LC, Bode AM, Al-Kali A, Litzow MR, Liu S. Inactivation of receptor tyrosine kinases reverts aberrant DNA methylation in acute myeloid leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28720666 DOI: 10.1158/1078-0432.CCR-17-0235  0.48
2017 Pang J, Shen N, Yan F, Zhao N, Dou L, Wu LC, Seiler CL, Yu L, Yang K, Bachanova V, Weaver E, Tretyakova NY, Liu S. Thymoquinone exerts potent growth-suppressive activity on leukemia through DNA hypermethylation reversal in leukemia cells. Oncotarget. PMID 28415607 DOI: 10.18632/oncotarget.16431  0.48
2016 Yang X, Pang J, Shen N, Yan F, Wu LC, Al-Kali A, Litzow MR, Peng Y, Lee RJ, Liu S. Liposomal bortezomib is active against chronic myeloid leukemia by disrupting the Sp1-BCR/ABL axis. Oncotarget. PMID 27144331 DOI: 10.18632/oncotarget.8871  0.48
2015 Yu XJ, Yang MJ, Zhou B, Wang GZ, Huang YC, Wu LC, Cheng X, Wen ZS, Huang JY, Zhang YD, Gao XH, Li GF, He SW, Gu ZH, Ma L, et al. Characterization of Somatic Mutations in Air Pollution-Related Lung Cancer. Ebiomedicine. 2: 583-590. PMID 26288819 DOI: 10.1016/j.ebiom.2015.04.003  0.48
2015 Liu Z, Liu JQ, Shi Y, Zhu X, Liu Z, Li MS, Yu J, Wu LC, He Y, Zhang G, Bai XF. Epstein-Barr virus-induced gene 3-deficiency leads to impaired antitumor T-cell responses and accelerated tumor growth. Oncoimmunology. 4: e989137. PMID 26140252 DOI: 10.4161/2162402X.2014.989137  0.48
2015 Agarwal HK, Khalil A, Ishita K, Yang W, Nakkula RJ, Wu LC, Ali T, Tiwari R, Byun Y, Barth RF, Tjarks W. Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer. European Journal of Medicinal Chemistry. 100: 197-209. PMID 26087030 DOI: 10.1016/j.ejmech.2015.05.042  1
2015 Young NA, Wu LC, Bruss M, Kaffenberger BH, Hampton J, Bolon B, Jarjour WN. A chimeric human-mouse model of Sjögren's syndrome. Clinical Immunology (Orlando, Fla.). 156: 1-8. PMID 25451161 DOI: 10.1016/j.clim.2014.10.004  1
2015 Jurkowitz MS, Patel A, Wu LC, Krautwater A, Pfeiffer DR, Bell CE. The YhhN protein of Legionella pneumophila is a Lysoplasmalogenase. Biochimica Et Biophysica Acta. 1848: 742-51. PMID 25445671 DOI: 10.1016/j.bbamem.2014.11.011  1
2014 Wu LC, Chiang CJ, Liu ZH, Tsuang YH, Sun JS, Huang YY. Fabrication and properties of acellular porcine anulus fibrosus for tissue engineering in spine surgery. Journal of Orthopaedic Surgery and Research. 9: 118. PMID 25466788 DOI: 10.1186/s13018-014-0118-z  0.44
2014 Young NA, Bruss MS, Gardner M, Willis WL, Mo X, Valiente GR, Cao Y, Liu Z, Jarjour WN, Wu LC. Oral administration of nano-emulsion curcumin in mice suppresses inflammatory-induced NFκB signaling and macrophage migration. Plos One. 9: e111559. PMID 25369140 DOI: 10.1371/journal.pone.0111559  1
2014 Deng Y, Chu J, Ren Y, Fan Z, Ji X, Mundy-Bosse B, Yuan S, Hughes T, Zhang J, Cheema B, Camardo AT, Xia Y, Wu LC, Wang LS, He X, et al. The natural product phyllanthusmin C enhances IFN-γ production by human NK cells through upregulation of TLR-mediated NF-κB signaling. Journal of Immunology (Baltimore, Md. : 1950). 193: 2994-3002. PMID 25122922 DOI: 10.4049/jimmunol.1302600  1
2014 Shen N, Yan F, Pang J, Wu LC, Al-Kali A, Litzow MR, Liu S. A nucleolin-DNMT1 regulatory axis in acute myeloid leukemogenesis. Oncotarget. 5: 5494-509. PMID 25015109 DOI: 10.18632/oncotarget.2131  0.48
2014 Young NA, Wu LC, Burd CJ, Friedman AK, Kaffenberger BH, Rajaram MV, Schlesinger LS, James H, Shupnik MA, Jarjour WN. Estrogen modulation of endosome-associated toll-like receptor 8: an IFNα-independent mechanism of sex-bias in systemic lupus erythematosus. Clinical Immunology (Orlando, Fla.). 151: 66-77. PMID 24525049 DOI: 10.1016/j.clim.2014.01.006  1
2014 Knapik DM, Perera P, Nam J, Blazek AD, Rath B, Leblebicioglu B, Das H, Wu LC, Hewett TE, Agarwal SK, Robling AG, Flanigan DC, Lee BS, Agarwal S. Mechanosignaling in bone health, trauma and inflammation. Antioxidants & Redox Signaling. 20: 970-85. PMID 23815527 DOI: 10.1089/ars.2013.5467  1
2013 Wu LC, Wen ZS, Qiu YT, Chen XQ, Chen HB, Wei MM, Liu Z, Jiang S, Zhou GB. Largazole Arrests Cell Cycle at G1 Phase and Triggers Proteasomal Degradation of E2F1 in Lung Cancer Cells. Acs Medicinal Chemistry Letters. 4: 921-6. PMID 24900585 DOI: 10.1021/ml400093y  0.48
2013 He S, Chu J, Wu LC, Mao H, Peng Y, Alvarez-Breckenridge CA, Hughes T, Wei M, Zhang J, Yuan S, Sandhu S, Vasu S, Benson DM, Hofmeister CC, He X, et al. MicroRNAs activate natural killer cells through Toll-like receptor signaling. Blood. 121: 4663-71. PMID 23580661 DOI: 10.1182/blood-2012-07-441360  1
2013 Yu J, Peng Y, Wu LC, Xie Z, Deng Y, Hughes T, He S, Mo X, Chiu M, Wang QE, He X, Liu S, Grever MR, Chan KK, Liu Z. Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia. Plos One. 8: e55934. PMID 23457487 DOI: 10.1371/journal.pone.0055934  1
2013 Liu Z, Liu JQ, Talebian F, Wu LC, Li S, Bai XF. IL-27 enhances the survival of tumor antigen-specific CD8+ T cells and programs them into IL-10-producing, memory precursor-like effector cells. European Journal of Immunology. 43: 468-79. PMID 23225163 DOI: 10.1002/eji.201242930  1
2013 Young NA, Friedman AK, Kaffenberger B, Rajaram MV, Birmingham DJ, Rovin BH, Hebert LA, Schlesinger LS, Wu LC, Jarjour WN. Novel estrogen target gene ZAS3 is overexpressed in systemic lupus erythematosus. Molecular Immunology. 54: 23-31. PMID 23178823 DOI: 10.1016/j.molimm.2012.10.026  1
2013 Hickey CJ, Schwind S, Radomska HS, Dorrance AM, Santhanam R, Mishra A, Wu YZ, Alachkar H, Maharry K, Nicolet D, Mrózek K, Walker A, Eiring AM, Whitman SP, Becker H, ... ... Wu LC, et al. Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia. Blood. 121: 159-69. PMID 23100311 DOI: 10.1182/blood-2012-05-428573  1
2012 Mishra A, Liu S, Sams GH, Curphey DP, Santhanam R, Rush LJ, Schaefer D, Falkenberg LG, Sullivan L, Jaroncyk L, Yang X, Fisk H, Wu LC, Hickey C, Chandler JC, et al. Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation. Cancer Cell. 22: 645-55. PMID 23153537 DOI: 10.1016/j.ccr.2012.09.009  1
2012 Du L, Xie Z, Wu LC, Chiu M, Lin J, Chan KK, Liu S, Liu Z. Reactivation of RASSF1A in breast cancer cells by curcumin. Nutrition and Cancer. 64: 1228-35. PMID 23145775 DOI: 10.1080/01635581.2012.717682  1
2011 Shin DH, Park KW, Wu LC, Hong JW. ZAS3 promotes TNFα-induced apoptosis by blocking NFϰB-activated expression of the anti-apoptotic genes TRAF1 and TRAF2. Bmb Reports. 44: 267-72. PMID 21524353 DOI: 10.5483/BMBRep.2011.44.4.267  1
2011 Wu LC, Pfeiffer DR, Calhoon EA, Madiai F, Marcucci G, Liu S, Jurkowitz MS. Purification, identification, and cloning of lysoplasmalogenase, the enzyme that catalyzes hydrolysis of the vinyl ether bond of lysoplasmalogen. The Journal of Biological Chemistry. 286: 24916-30. PMID 21515882 DOI: 10.1074/jbc.M111.247163  1
2011 Liu S, Madiai F, Hackshaw KV, Allen CE, Carl J, Huschart E, Karanfilov C, Litsky A, Hickey CJ, Marcucci G, Huja S, Agarwal S, Yu J, Caligiuri MA, Wu LC. The large zinc finger protein ZAS3 is a critical modulator of osteoclastogenesis. Plos One. 6: e17161. PMID 21390242 DOI: 10.1371/journal.pone.0017161  1
2011 Yakovich AJ, Jiang B, Allen CE, Du J, Wu LC, Barnard JA. ZAS3 accentuates transforming growth factor β signaling in epithelial cells. Cellular Signalling. 23: 105-13. PMID 20732416 DOI: 10.1016/j.cellsig.2010.08.009  1
2010 Hong JW, Wu LC. ZAS3 represses NFκB-dependent transcription by direct competition for DNA binding. Bmb Reports. 43: 807-12. PMID 21189157 DOI: 10.5483/BMBRep.2010.43.12.807  1
2010 Liu JQ, Joshi PS, Wang C, El-Omrani HY, Xiao Y, Liu X, Hagan JP, Liu CG, Wu LC, Bai XF. Targeting activation-induced cytidine deaminase overcomes tumor evasion of immunotherapy by CTLs. Journal of Immunology (Baltimore, Md. : 1950). 184: 5435-43. PMID 20404277 DOI: 10.4049/jimmunol.0903322  0.48
2010 Liu S, Wu LC, Pang J, Santhanam R, Schwind S, Wu YZ, Hickey CJ, Yu J, Becker H, Maharry K, Radmacher MD, Li C, Whitman SP, Mishra A, Stauffer N, et al. Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia. Cancer Cell. 17: 333-47. PMID 20385359 DOI: 10.1016/j.ccr.2010.03.008  1
2009 Garzon R, Liu S, Fabbri M, Liu Z, Heaphy CE, Callegari E, Schwind S, Pang J, Yu J, Muthusamy N, Havelange V, Volinia S, Blum W, Rush LJ, Perrotti D, ... ... Wu LC, et al. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood. 113: 6411-8. PMID 19211935 DOI: 10.1182/blood-2008-07-170589  1
2009 Liu Z, Liu S, Xie Z, Pavlovicz RE, Wu J, Chen P, Aimiuwu J, Pang J, Bhasin D, Neviani P, Fuchs JR, Plass C, Li PK, Li C, Huang TH, ... Wu LC, et al. Modulation of DNA methylation by a sesquiterpene lactone parthenolide. The Journal of Pharmacology and Experimental Therapeutics. 329: 505-14. PMID 19201992 DOI: 10.1124/jpet.108.147934  1
2008 Liu S, Liu Z, Xie Z, Pang J, Yu J, Lehmann E, Huynh L, Vukosavljevic T, Takeki M, Klisovic RB, Baiocchi RA, Blum W, Porcu P, Garzon R, Byrd JC, ... ... Wu LC, et al. Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia. Blood. 111: 2364-73. PMID 18083845 DOI: 10.1182/blood-2007-08-110171  1
2007 Allen CE, Richards J, Muthusamy N, Auer H, Liu Y, Robinson ML, Barnard JA, Wu LC. Disruption of ZAS3 in mice alters NF-kappaB and AP-1 DNA binding and T-cell development. Gene Expression. 14: 83-100. PMID 18257392 DOI: 10.3727/105221607783417574  1
2007 Yu J, Wei M, Boyd Z, Lehmann EB, Trotta R, Mao H, Liu S, Becknell B, Jaung MS, Jarjoura D, Marcucci G, Wu LC, Caligiuri MA. Transcriptional control of human T-BET expression: the role of Sp1. European Journal of Immunology. 37: 2549-61. PMID 17705132 DOI: 10.1002/eji.200737088  0.48
2005 Hong JW, Wu LC. Structural characterization of the gene encoding the large zinc finger protein ZAS3: implication to the origin of multiple promoters in eukaryotic genes. Biochimica Et Biophysica Acta. 1681: 74-87. PMID 15627499 DOI: 10.1016/j.bbaexp.2004.10.004  1
2003 Hong JW, Allen CE, Wu LC. Inhibition of NF-kappaB by ZAS3, a zinc-finger protein that also binds to the kappaB motif. Proceedings of the National Academy of Sciences of the United States of America. 100: 12301-6. PMID 14530385 DOI: 10.1073/pnas.2133048100  1
2002 Allen CE, Muthusamy N, Weisbrode SE, Hong JW, Wu LC. Developmental anomalies and neoplasia in animals and cells deficient in the large zinc finger protein KRC. Genes, Chromosomes & Cancer. 35: 287-98. PMID 12378523 DOI: 10.1002/gcc.10128  1
2002 Allen CE, Mak CH, Wu LC. The kappa B transcriptional enhancer motif and signal sequences of V(D)J recombination are targets for the zinc finger protein HIVEP3/KRC: a site selection amplification binding study. Bmc Immunology. 3: 10. PMID 12193271 DOI: 10.1186/1471-2172-3-10  1
2002 Wu LC. ZAS: C2H2 zinc finger proteins involved in growth and development. Gene Expression. 10: 137-52. PMID 12173742  1
2002 Hicar MD, Robinson ML, Wu LC. Embryonic expression and regulation of the large zinc finger protein KRC. Genesis (New York, N.Y. : 2000). 33: 8-20. PMID 12001065 DOI: 10.1002/gene.10084  1
2002 Oukka M, Kim ST, Lugo G, Sun J, Wu LC, Glimcher LH. A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2. Molecular Cell. 9: 121-31. PMID 11804591 DOI: 10.1016/S1097-2765(01)00434-8  1
2001 Wu LC, Hicar MD, Hong J, Allen CE. The DNA-binding ability of HIVEP3/KRC decreases upon activation of V(D)J recombination. Immunogenetics. 53: 564-71. PMID 11685469 DOI: 10.1007/s002510100360  1
2001 Hicar MD, Liu Y, Allen CE, Wu LC. Structure of the human zinc finger protein HIVEP3: molecular cloning, expression, exon-intron structure, and comparison with paralogous genes HIVEP1 and HIVEP2. Genomics. 71: 89-100. PMID 11161801 DOI: 10.1006/geno.2000.6425  1
2000 Allen CE, Wu LC. Downregulation of KRC induces proliferation, anchorage independence, and mitotic cell death in HeLa cells. Experimental Cell Research. 260: 346-56. PMID 11035930 DOI: 10.1006/excr.2000.5029  1
2000 Hjelmsoe I, Allen CE, Cohn MA, Tulchinsky EM, Wu LC. The kappaB and V(D)J recombination signal sequence binding protein KRC regulates transcription of the mouse metastasis-associated gene S100A4/mts1. The Journal of Biological Chemistry. 275: 913-20. PMID 10625627 DOI: 10.1074/jbc.275.2.913  1
1994 Dangel AW, Mendoza AR, Baker BJ, Daniel CM, Carroll MC, Wu LC, Yu CY. The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates. Immunogenetics. 40: 425-36. PMID 7545960 DOI: 10.1007/BF00177825  1
1987 Wu LC, Morley BJ, Campbell RD. Cell-specific expression of the human complement protein factor B gene: evidence for the role of two distinct 5'-flanking elements. Cell. 48: 331-42. PMID 3643061 DOI: 10.1016/0092-8674(87)90436-3  1
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