Adegboyega Oyelere - Publications

Chemistry and Biochemistry Georgia Institute of Technology, Atlanta, GA 
Pharmaceutical Chemistry, Biochemistry, Physical Chemistry

47/68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Khodaverdian V, Tapadar S, MacDonald IA, Xu Y, Ho PY, Bridges A, Rajpurohit P, Sanghani BA, Fan Y, Thangaraju M, Hathaway NA, Oyelere AK. Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study. Scientific Reports. 9: 4802. PMID 30886160 DOI: 10.1038/s41598-019-39214-1  0.4
2018 Story S, Skriba MJ, Maiti K, Nihar Ranjan, Degtyareva NN, Green KD, Khodaverdian V, Oyelere AK, Garneau-Tsodikova S, Arya DP. Synthesis, antimicrobial activity, attenuation of aminoglycoside resistance in MRSA, and ribosomal A-site binding of pyrene-neomycin conjugates. European Journal of Medicinal Chemistry. 163: 381-393. PMID 30530174 DOI: 10.1016/j.ejmech.2018.11.022  0.32
2017 Degtyareva NN, Gong C, Story S, Levinson N, Oyelere AK, Green KD, Garneau-Tsodikova S, Arya DP. Antimicrobial Activity, AME Resistance and Translation Inhibition Studies of Anthraquinone-Neomycin Conjugates. Acs Infectious Diseases. PMID 28103015 DOI: 10.1021/acsinfecdis.6b00176  0.32
2015 Tapadar S, Fathi S, Raji I, Omesiete W, Kornacki JR, Mwakwari SC, Miyata M, Mitsutake K, Li JD, Mrksich M, Oyelere AK. A structure-activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities. Bioorganic & Medicinal Chemistry. PMID 26585275 DOI: 10.1016/j.bmc.2015.10.045  0.8
2015 Washington AZ, Tapadar S, George A, Oyelere AK. Exploiting translational stalling peptides in an effort to extend azithromycin interaction within the prokaryotic ribosome nascent peptide exit tunnel. Bioorganic & Medicinal Chemistry. 23: 5198-209. PMID 26037612 DOI: 10.1016/j.bmc.2015.04.078  0.8
2015 Sodji QH, Kornacki JR, McDonald JF, Mrksich M, Oyelere AK. Design and structure activity relationship of tumor-homing histone deacetylase inhibitors conjugated to folic and pteroic acids. European Journal of Medicinal Chemistry. 96: 340-59. PMID 25899338 DOI: 10.1016/j.ejmech.2015.04.014  0.8
2015 Jiang L, Watkins D, Jin Y, Gong C, King A, Washington AZ, Green KD, Garneau-Tsodikova S, Oyelere AK, Arya DP. Rapid synthesis, RNA binding, and antibacterial screening of a peptidic-aminosugar (PA) library. Acs Chemical Biology. 10: 1278-89. PMID 25706406 DOI: 10.1021/cb5010367  0.8
2015 Owumi SE, Oyelere AK. Determination of metal ion contents of two antiemetic clays use in Geophagy Toxicology Reports. 2: 928-932. DOI: 10.1016/j.toxrep.2015.06.008  0.8
2014 Sodji Q, Patil V, Jain S, Kornacki JR, Mrksich M, Tekwani BL, Oyelere AK. The antileishmanial activity of isoforms 6- and 8-selective histone deacetylase inhibitors Bioorganic and Medicinal Chemistry Letters. 24: 4826-4830. PMID 25240614 DOI: 10.1016/j.bmcl.2014.08.060  0.8
2014 Washington AZ, Benicewicz DB, Canzoneri JC, Fagan CE, Mwakwari SC, Maehigashi T, Dunham CM, Oyelere AK. Macrolide-peptide conjugates as probes of the path of travel of the nascent peptides through the ribosome. Acs Chemical Biology. 9: 2621-31. PMID 25198768 DOI: 10.1021/cb5003224  0.8
2014 Dreaden EC, Raji IO, Austin LA, Fathi S, Mwakwari SC, Humphries WH, Kang B, Oyelere AK, El-Sayed MA. P-glycoprotein-dependent trafficking of nanoparticle-drug conjugates. Small (Weinheim An Der Bergstrasse, Germany). 10: 1719-23. PMID 24616407 DOI: 10.1002/smll.201303190  0.8
2013 Sodji QH, Patil V, Kornacki JR, Mrksich M, Oyelere AK. Synthesis and structure-activity relationship of 3-hydroxypyridine-2-thione-based histone deacetylase inhibitors. Journal of Medicinal Chemistry. 56: 9969-81. PMID 24304348 DOI: 10.1021/jm401225q  0.6
2013 Gryder BE, Akbashev MJ, Rood MK, Raftery ED, Meyers WM, Dillard P, Khan S, Oyelere AK. Selectively targeting prostate cancer with antiandrogen equipped histone deacetylase inhibitors. Acs Chemical Biology. 8: 2550-60. PMID 24004176 DOI: 10.1021/cb400542w  0.8
2013 Gryder BE, Rood MK, Johnson KA, Patil V, Raftery ED, Yao LP, Rice M, Azizi B, Doyle DF, Oyelere AK. Histone deacetylase inhibitors equipped with estrogen receptor modulation activity. Journal of Medicinal Chemistry. 56: 5782-96. PMID 23786452 DOI: 10.1021/jm400467w  0.8
2013 Guerrant W, Patil V, Canzoneri JC, Yao LP, Hood R, Oyelere AK. Dual-acting histone deacetylase-topoisomerase I inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 3283-7. PMID 23622981 DOI: 10.1016/j.bmcl.2013.03.108  0.8
2013 Patil V, Sodji QH, Kornacki JR, Mrksich M, Oyelere AK. 3-Hydroxypyridin-2-thione as Novel Zinc Binding Group for Selective Histone Deacetylase Inhibition Journal of Medicinal Chemistry. 56: 3492-3506. PMID 23547652 DOI: 10.1021/jm301769u  0.8
2013 Sodji QH, Patil V, Kornacki JR, Mrksich M, Oyelere AK. Synthesis and structure-activity relationship of 3-hydroxypyridine-2- thione-based histone deacetylase inhibitors Journal of Medicinal Chemistry. 56: 9969-9981. DOI: 10.1021/jm401225q  0.8
2012 Patil V, Canzoneri JC, Samatov TR, Lührmann R, Oyelere AK. Molecular architecture of zinc chelating small molecules that inhibit spliceosome assembly at an early stage. Rna (New York, N.Y.). 18: 1605-11. PMID 22832025 DOI: 10.1261/rna.034819.112  0.8
2012 Dreaden EC, Mwakwari SC, Austin LA, Kieffer MJ, Oyelere AK, El-Sayed MA. Small molecule-gold nanorod conjugates selectively target and induce macrophage cytotoxicity towards breast cancer cells. Small (Weinheim An Der Bergstrasse, Germany). 8: 2819-22. PMID 22777707 DOI: 10.1002/smll.201200333  0.8
2012 Dreaden EC, Gryder BE, Austin LA, Tene Defo BA, Hayden SC, Pi M, Quarles LD, Oyelere AK, El-Sayed MA. Antiandrogen gold nanoparticles dual-target and overcome treatment resistance in hormone-insensitive prostate cancer cells. Bioconjugate Chemistry. 23: 1507-12. PMID 22768914 DOI: 10.1021/bc300158k  0.8
2012 Gryder BE, Sodji QH, Oyelere AK. Targeted cancer therapy: giving histone deacetylase inhibitors all they need to succeed. Future Medicinal Chemistry. 4: 505-24. PMID 22416777 DOI: 10.4155/fmc.12.3  0.8
2012 Guerrant W, Patil V, Canzoneri JC, Oyelere AK. Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors. Journal of Medicinal Chemistry. 55: 1465-77. PMID 22260166 DOI: 10.1021/jm200799p  0.8
2011 Gryder BE, Guerrant W, Chen CH, Oyelere AK. Oxathiazole-2-one derivative of bortezomib: Synthesis, stability and proteasome inhibition activity Medchemcomm. 2: 1083-1086. DOI: 10.1039/c1md00208b  0.8
2010 Huang X, Kang B, Qian W, Mackey MA, Chen PC, Oyelere AK, El-Sayed IH, El-Sayed MA. Comparative study of photothermolysis of cancer cells with nuclear-targeted or cytoplasm-targeted gold nanospheres: continuous wave or pulsed lasers. Journal of Biomedical Optics. 15: 058002. PMID 21054128 DOI: 10.1117/1.3486538  0.8
2010 Oyelere AK. Macrocycles in medicinal chemistry and drug discovery. Current Topics in Medicinal Chemistry. 10: 1359-60. PMID 20919989 DOI: 10.2174/156802610792232097  0.8
2010 Mwakwari SC, Guerrant W, Patil V, Khan SI, Tekwani BL, Gurard-Levin ZA, Mrksich M, Oyelere AK. Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton Journal of Medicinal Chemistry. 53: 6100-6111. PMID 20669972 DOI: 10.1021/jm100507q  0.8
2010 Mwakwari SC, Patil V, Guerrant W, Oyelere AK. Macrocyclic histone deacetylase inhibitors. Current Topics in Medicinal Chemistry. 10: 1423-40. PMID 20536416 DOI: 10.2174/156802610792232079  0.8
2010 Guerrant W, Mwakwari SC, Chen PC, Khan SI, Tekwani BL, Oyelere AK. A structure-activity relationship study of the antimalarial and antileishmanial activities of nonpeptide macrocyclic histone deacetylase inhibitors. Chemmedchem. 5: 1232-5. PMID 20533500 DOI: 10.1002/cmdc.201000087  0.8
2010 Patil V, Guerrant W, Chen PC, Gryder B, Benicewicz DB, Khan SI, Tekwani BL, Oyelere AK. Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group. Bioorganic & Medicinal Chemistry. 18: 415-25. PMID 19914074 DOI: 10.1016/j.bmc.2009.10.042  0.8
2009 Dreaden EC, Mwakwari SC, Sodji QH, Oyelere AK, El-Sayed MA. Tamoxifen-poly(ethylene glycol)-thiol gold nanoparticle conjugates: enhanced potency and selective delivery for breast cancer treatment. Bioconjugate Chemistry. 20: 2247-53. PMID 19919059 DOI: 10.1021/bc9002212  0.8
2009 Canzoneri JC, Chen PC, Oyelere AK. Design and synthesis of novel histone deacetylase inhibitor derived from nuclear localization signal peptide. Bioorganic & Medicinal Chemistry Letters. 19: 6588-90. PMID 19854643 DOI: 10.1016/j.bmcl.2009.10.028  0.8
2009 Oyelere AK, Chen PC, Guerrant W, Mwakwari SC, Hood R, Zhang Y, Fan Y. Non-peptide macrocyclic histone deacetylase inhibitors. Journal of Medicinal Chemistry. 52: 456-68. PMID 19093884 DOI: 10.1021/jm801128g  0.8
2008 Chen PC, Mwakwari SC, Oyelere AK. Gold nanoparticles: From nanomedicine to nanosensing. Nanotechnology, Science and Applications. 1: 45-65. PMID 24198460  0.8
2008 Canzoneri JC, Oyelere AK. Interaction of anthracyclines with iron responsive element mRNAs. Nucleic Acids Research. 36: 6825-34. PMID 18953029 DOI: 10.1093/nar/gkn774  0.8
2008 Chen PC, Patil V, Guerrant W, Green P, Oyelere AK. Synthesis and structure-activity relationship of histone deacetylase (HDAC) inhibitors with triazole-linked cap group. Bioorganic & Medicinal Chemistry. 16: 4839-53. PMID 18397827 DOI: 10.1016/j.bmc.2008.03.050  0.8
2007 Chen PC, Wharton RE, Patel PA, Oyelere AK. Direct diazo-transfer reaction on beta-lactam: synthesis and preliminary biological activities of 6-triazolylpenicillanic acids. Bioorganic & Medicinal Chemistry. 15: 7288-300. PMID 17855098 DOI: 10.1016/j.bmc.2007.08.035  0.8
2007 Oyelere AK, Chen PC, Huang X, El-Sayed IH, El-Sayed MA. Peptide-conjugated gold nanorods for nuclear targeting. Bioconjugate Chemistry. 18: 1490-7. PMID 17630680 DOI: 10.1021/bc070132i  0.8
2006 Oyelere AK, Chen PC, Yao LP, Boguslavsky N. Heterogeneous diazo-transfer reaction: a facile unmasking of azide groups on amine-functionalized insoluble supports for solid-phase synthesis. The Journal of Organic Chemistry. 71: 9791-6. PMID 17168598 DOI: 10.1021/jo0618122  0.8
2003 Strobel SA, Jones FD, Oyelere AK, Ryder SP. Biochemical detection of adenosine and cytidine ionization within RNA by interference analysis. Nucleic Acids Research. Supplement (2001). 229-30. PMID 14510464  0.8
2003 Cho HD, Oyelere AK, Strobel SA, Weiner AM. Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection. Rna (New York, N.Y.). 9: 970-81. PMID 12869708 DOI: 10.1261/rna.2110903  0.8
2002 Oyelere AK, Kardon JR, Strobel SA. pK(a) perturbation in genomic Hepatitis Delta Virus ribozyme catalysis evidenced by nucleotide analogue interference mapping. Biochemistry. 41: 3667-75. PMID 11888283 DOI: 10.1021/bi011816v  0.8
2001 Oyelere AK, Strobel SA. Site specific incorporation of 6-azauridine into the genomic HDV ribozyme active site. Nucleosides, Nucleotides & Nucleic Acids. 20: 1851-8. PMID 11719998 DOI: 10.1081/NCN-100107196  0.8
2001 Ryder SP, Oyelere AK, Padilla JL, Klostermeier D, Millar DP, Strobel SA. Investigation of adenosine base ionization in the hairpin ribozyme by nucleotide analog interference mapping. Rna (New York, N.Y.). 7: 1454-63. PMID 11680850  0.8
2000 Oyelere AK, Strobel SA. Biochemical detection of cytidine protonation within RNA Journal of the American Chemical Society. 122: 10259-10267. DOI: 10.1021/ja001918t  0.8
1999 Szewczak AA, Ortoleva-Donnelly L, Zivarts MV, Oyelere AK, Kazantsev AV, Strobel SA. An important base triple anchors the substrate helix recognition surface within the Tetrahymena ribozyme active site. Proceedings of the National Academy of Sciences of the United States of America. 96: 11183-8. PMID 10500151 DOI: 10.1073/pnas.96.20.11183  0.8
1997 Oliver JS, Oyelere AK. Efficient preparation of aminoacylated dinucleoside phosphates with N-FMOC amino acid fluorides Tetrahedron Letters. 38: 4005-4008. DOI: 10.1016/S0040-4039(97)00820-4  0.8
1996 Oliver JS, Oyelere A. Aminoacylation of nucleosides with FMOC amino acid fluorides Journal of Organic Chemistry. 61: 4168-4171. DOI: 10.1021/jo9601674  0.8
Low-probability matches
2016 Raji I, Yadudu F, Janeira E, Fathi S, Szymczak L, Kornacki JR, Komatsu K, Li JD, Mrksich M, Oyelere AK. Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase. Bioorganic & Medicinal Chemistry. PMID 28057407 DOI: 10.1016/j.bmc.2016.12.032  0.24
2020 Jia YF, Jeeva S, Xu J, Heppelmann CJ, Jang JS, Slama MQ, Tapadar S, Oyelere AK, Kang SM, Matveyenko AV, Peterson QP, Shin CH. TBK1 regulates regeneration of pancreatic β-cells. Scientific Reports. 10: 19374. PMID 33168920 DOI: 10.1038/s41598-020-76600-6  0.2
2020 Tapadar S, Fathi S, Wu B, Sun CQ, Raji I, Moore SG, Arnold RS, Gaul DA, Petros JA, Oyelere AK. Liver-Targeting Class I Selective Histone Deacetylase Inhibitors Potently Suppress Hepatocellular Tumor Growth as Standalone Agents. Cancers. 12. PMID 33114147 DOI: 10.3390/cancers12113095  0.2
2020 Caggia S, Tapadar S, Wu B, Venugopal SV, Garrett AS, Kumar A, Stiffend JS, Davis JS, Oyelere AK, Khan SA. Small Molecule Inhibitors Targeting Gα2 Protein Attenuate Migration of Cancer Cells. Cancers. 12. PMID 32575572 DOI: 10.3390/cancers12061631  0.2
2019 Xu J, Jia YF, Tapadar S, Weaver JD, Raji IO, Pithadia DJ, Javeed N, García AJ, Choi DS, Matveyenko AV, Oyelere AK, Shin CH. Publisher Correction: Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells. Scientific Reports. 9: 18570. PMID 31796771 DOI: 10.1038/s41598-019-54301-z  0.2
2018 Xu J, Jia YF, Tapadar S, Weaver JD, Raji IO, Pithadia DJ, Javeed N, García AJ, Choi DS, Matveyenko AV, Oyelere AK, Shin CH. Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells. Scientific Reports. 8: 15587. PMID 30349097 DOI: 10.1038/s41598-018-33875-0  0.2
2018 George A, Raji I, Cinar B, Kucuk O, Oyelere AK. Design, synthesis, and evaluation of the antiproliferative activity of hydantoin-derived antiandrogen-genistein conjugates. Bioorganic & Medicinal Chemistry. PMID 29456113 DOI: 10.1016/j.bmc.2018.01.009  0.2
2008 Zhou J, Bhattacharjee A, Chen S, Chen Y, Duffy E, Farmer J, Goldberg J, Hanselmann R, Ippolito JA, Lou R, Orbin A, Oyelere A, Salvino J, Springer D, Tran J, et al. Design at the atomic level: generation of novel hybrid biaryloxazolidinones as promising new antibiotics. Bioorganic & Medicinal Chemistry Letters. 18: 6179-83. PMID 18951792 DOI: 10.1016/j.bmcl.2008.10.014  0.16
2008 Zhou J, Bhattacharjee A, Chen S, Chen Y, Duffy E, Farmer J, Goldberg J, Hanselmann R, Ippolito JA, Lou R, Orbin A, Oyelere A, Salvino J, Springer D, Tran J, et al. Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics. Bioorganic & Medicinal Chemistry Letters. 18: 6175-8. PMID 18947996 DOI: 10.1016/j.bmcl.2008.10.011  0.16
2020 Wu B, Fathi S, Mortley S, Mohiuddin M, Jang YC, Oyelere AK. Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity. Bioorganic & Medicinal Chemistry. 115345. PMID 32061484 DOI: 10.1016/j.bmc.2020.115345  0.04
2019 Crooke SN, Schimer J, Raji I, Wu B, Oyelere AK, Finn MG. Lung Tissue Delivery of Virus-Like Particles Mediated by Macrolide Antibiotics. Molecular Pharmaceutics. PMID 31244221 DOI: 10.1021/acs.molpharmaceut.9b00180  0.04
2020 Owumi SE, Adedara IA, Farombi EO, Oyelere AK. Protocatechuic acid modulates reproductive dysfunction linked to furan exposure in rats. Toxicology. 442: 152556. PMID 32758512 DOI: 10.1016/j.tox.2020.152556  0.01
2020 Owumi SE, Adedara IA, Akomolafe AP, Farombi EO, Oyelere AK. Gallic acid enhances reproductive function by modulating oxido-inflammatory and apoptosis mediators in rats exposed to aflatoxin-B1. Experimental Biology and Medicine (Maywood, N.J.). 1535370220936206. PMID 32558593 DOI: 10.1177/1535370220936206  0.01
2020 Owumi S, Najophe ES, Farombi EO, Oyelere AK. Gallic acid protects against Aflatoxin B -induced oxidative and inflammatory stress damage in rats kidneys and liver. Journal of Food Biochemistry. e13316. PMID 32496616 DOI: 10.1111/jfbc.13316  0.01
2018 Oyebode OT, Owumi SE, Oyelere AK, Olorunsogo OO. Calliandra portoricensis Benth exhibits anticancer effects via alteration of Bax/Bcl-2 ratio and growth arrest in prostate LNCaP cells. Journal of Ethnopharmacology. PMID 30580026 DOI: 10.1016/j.jep.2018.12.020  0.01
2018 Sun C, Tapadar S, Gaul D, Arnold R, Oyelere A, Petros J. MP87-10 NEW DESIGNER DRUGS FOR CASTRATION RESISTANT PROSTATE CANCER Journal of Urology. 199. DOI: 10.1016/j.juro.2018.02.2910  0.01
2017 Pavlova A, Parks JM, Oyelere AK, Gumbart JC. Toward the rational design of macrolide antibiotics to combat resistance. Chemical Biology & Drug Design. PMID 28419786 DOI: 10.1111/cbdd.13004  0.01
2017 Raji I, Ahluwalia K, Oyelere AK. Design, synthesis and evaluation of antiproliferative activity of melanoma-targeted histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 28131715 DOI: 10.1016/j.bmcl.2017.01.044  0.01
2016 Fathi S, Oyelere AK. Liposomal drug delivery systems for targeted cancer therapy: is active targeting the best choice? Future Medicinal Chemistry. PMID 27774793 DOI: 10.4155/fmc-2016-0135  0.01
2015 Owumi SE, Oyelere AK. Determination of metal ion contents of two antiemetic clays use in Geophagy. Toxicology Reports. 2: 928-932. PMID 28962431 DOI: 10.1016/j.toxrep.2015.06.008  0.01
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