Eric Wickstrom - Publications

Affiliations: 
Molecular Pharmacology and Structural Biology Thomas Jefferson University, Philadelphia, PA, United States 
Area:
General Biophysics, Condensed Matter Physics, Computer Science

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kumar P, Tripathi SK, Chen CP, Wickstrom E, Thakur ML. Evaluating Ga-68 Peptide Conjugates for Targeting VPAC Receptors: Stability and Pharmacokinetics. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 29802552 DOI: 10.1007/S11307-018-1207-X  0.307
2018 Oh E, Liu Y, Sonar MV, Merry D, Wickstrom E. Fluorescence Imaging of Huntingtin mRNA Knockdown. Bioconjugate Chemistry. PMID 29451775 DOI: 10.1021/Acs.Bioconjchem.8B00048  0.345
2018 Jin Y, Wickstrom E. Abstract A57: Antisense oligonucleotide therapeutics with receptor-targeted delivery in triple-negative breast cancer cells via microRNA blockade without passenger strand side effects Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-A57  0.319
2016 Kumar P, Tripathi SK, Chen CP, Mehta N, Paudyal B, Wickstrom E, Thakur ML. Evaluation of a PACAP Peptide Analogue Labeled with (68)Ga Using Two Different Chelating Agents. Cancer Biotherapy & Radiopharmaceuticals. 31: 29-36. PMID 26844850 DOI: 10.1089/Cbr.2015.1947  0.311
2015 Wampole ME, Paudyal B, Trabulsi EJ, Thakur ML, Wickstrom E. Abstract 1487: Rotating 3D projections of prostate lesions imaged by Cu-64-VPAC1 ligand PET and CT Cancer Research. 75: 1487-1487. DOI: 10.1158/1538-7445.Am2015-1487  0.305
2015 Trabulsi EJ, Kumar P, Tripathi S, Birbe R, McCue P, Wickstrom E, Intenzo C, Kim S, Den R, Gomella L, Thakur ML. Abstract 1485: Pilot study of VPAC1 targeted PET imaging of prostate cancer Cancer Research. 75: 1485-1485. DOI: 10.1158/1538-7445.Am2015-1485  0.327
2015 Trabulsi E, Tripathi S, McCue P, Birbe R, Wickstrom E, Gomella L, Kim S, Intenzo C, Thakur M. Pd4-09 Vasoactive Intestinal Peptide And Pituitary Adenylate Cyclase Activating Peptide Receptor 1 (Vpac1) Targeted Imaging Of Prostate Cancer: A Pilot Study The Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.321  0.314
2014 Sonar MV, Wampole ME, Jin YY, Chen CP, Thakur ML, Wickstrom E. Fluorescence detection of KRAS2 mRNA hybridization in lung cancer cells with PNA-peptides containing an internal thiazole orange. Bioconjugate Chemistry. 25: 1697-708. PMID 25180641 DOI: 10.1021/Bc500304M  0.362
2014 Wickstrom E, Chen C, Wampole ME, Zhang K, Paudyal B, Wang A, Tripathi S, Kumar P, Mitchell EP, Lu B, Thakur ML, Gray BD, Mattis JA. Abstract B55: Hypoxanthine wobble base multimutant KRAS2 mRNA PET imaging agent in G12D mice Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B55  0.363
2013 Paudyal B, Zhang K, Chen CP, Wampole ME, Mehta N, Mitchell EP, Gray BD, Mattis JA, Pak KY, Thakur ML, Wickstrom E. Determining efficacy of breast cancer therapy by PET imaging of HER2 mRNA. Nuclear Medicine and Biology. 40: 994-9. PMID 24074944 DOI: 10.1016/J.Nucmedbio.2013.08.005  0.318
2013 Sanders JM, Wampole ME, Chen CP, Sethi D, Singh A, Dupradeau FY, Wang F, Gray BD, Thakur ML, Wickstrom E. Effects of hypoxanthine substitution in peptide nucleic acids targeting KRAS2 oncogenic mRNA molecules: theory and experiment. The Journal of Physical Chemistry. B. 117: 11584-95. PMID 23972113 DOI: 10.1021/Jp4064966  0.613
2013 Sanders JM, Wampole ME, Thakur ML, Wickstrom E. Molecular determinants of epidermal growth factor binding: a molecular dynamics study. Plos One. 8: e54136. PMID 23382875 DOI: 10.1371/Journal.Pone.0054136  0.569
2013 Wickstrom E, Chen C, Paudyal B, Wampole ME, Zhang K, Wang A, Lu B, Thakur ML. Abstract 4534: Mutant KRAS2 mRNA PET imaging in spontaneous transgenic lung cancers. Cancer Research. 73: 4534-4534. DOI: 10.1158/1538-7445.Am2013-4534  0.339
2013 Olejniczak AB, Kierzek R, Wickstrom E, Lesnikowski ZJ. Synthesis, physicochemical and biochemical studies of anti-IRS-1 oligonucleotides containing carborane and/or metallacarborane modification Journal of Organometallic Chemistry. 747: 201-210. DOI: 10.1016/J.Jorganchem.2013.05.022  0.326
2012 Sethi D, Chen CP, Jing RY, Thakur ML, Wickstrom E. Fluorescent peptide-PNA chimeras for imaging monoamine oxidase A mRNA in neuronal cells. Bioconjugate Chemistry. 23: 158-63. PMID 22239616 DOI: 10.1021/Bc2004507  0.344
2011 Wickstrom E, Chen CP, Devadhas D, Wampole M, Jin YY, Sanders JM, Kairys JC, Ankeny ML, Hu R, Barner KE, Steiner KV, Thakur ML. Three dimensional projection environment for molecular design and surgical simulation. Studies in Health Technology and Informatics. 163: 691-5. PMID 21335882 DOI: 10.3233/978-1-60750-706-2-691  0.56
2010 Opitz AW, Wickstrom E, Thakur ML, Wagner NJ. Physiologically based pharmacokinetics of molecular imaging nanoparticles for mRNA detection determined in tumor-bearing mice. Oligonucleotides. 20: 117-25. PMID 20406142 DOI: 10.1089/Oli.2009.0216  0.324
2010 Amirkhanov NV, Zhang K, Aruva MR, Thakur ML, Wickstrom E. Imaging human pancreatic cancer xenografts by targeting mutant KRAS2 mRNA with [(111)In]DOTA(n)-poly(diamidopropanoyl)(m)-KRAS2 PNA-D(Cys-Ser-Lys-Cys) nanoparticles. Bioconjugate Chemistry. 21: 731-40. PMID 20232877 DOI: 10.1021/Bc900523C  0.333
2010 Thakur ML, Devadhas D, Zhang K, Pestell RG, Wang C, McCue P, Wickstrom E. Imaging spontaneous MMTVneu transgenic murine mammary tumors: targeting metabolic activity versus genetic products. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 106-11. PMID 20008985 DOI: 10.2967/Jnumed.109.069542  0.319
2010 Panchapakesan B, Velasco V, Jing R, Talati P, Zibelli AM, Wickstrom E. Abstract LB-72: Rapid detection and profiling of breast cancer cells in blood applied to arrays of carbon nanotube thin film biosensors Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-72  0.304
2008 Shao N, Wickstrom E, Panchapakesan B. Nanotube-antibody biosensor arrays for the detection of circulating breast cancer cells. Nanotechnology. 19: 465101. PMID 21836232 DOI: 10.1088/0957-4484/19/46/465101  0.31
2008 Amirkhanov NV, Dimitrov I, Opitz AW, Zhang K, Lackey JP, Cardi CA, Lai S, Wagner NJ, Thakur ML, Wickstrom E. Design of (Gd-DO3A)n-polydiamidopropanoyl-peptide nucleic acid-D(Cys-Ser-Lys-Cys) magnetic resonance contrast agents. Biopolymers. 89: 1061-76. PMID 18680101 DOI: 10.1002/Bip.21059  0.339
2008 Tian X, Michal AM, Li P, Wolfe HR, Waldman SA, Wickstrom E. STa peptide analogs for probing guanylyl cyclase C. Biopolymers. 90: 713-23. PMID 18615494 DOI: 10.1002/Bip.21045  0.304
2008 Zhang K, Aruva MR, Shanthly N, Cardi CA, Rattan S, Patel C, Kim C, McCue PA, Wickstrom E, Thakur ML. PET imaging of VPAC1 expression in experimental and spontaneous prostate cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 112-21. PMID 18077536 DOI: 10.2967/Jnumed.107.043703  0.3
2007 Cesarone G, Edupuganti OP, Chen CP, Wickstrom E. Insulin receptor substrate 1 knockdown in human MCF7 ER+ breast cancer cells by nuclease-resistant IRS1 siRNA conjugated to a disulfide-bridged D-peptide analogue of insulin-like growth factor 1. Bioconjugate Chemistry. 18: 1831-40. PMID 17922544 DOI: 10.1021/Bc070135V  0.353
2007 Tian X, Aruva MR, Zhang K, Shanthly N, Cardi CA, Thakur ML, Wickstrom E. PET imaging of CCND1 mRNA in human MCF7 estrogen receptor positive breast cancer xenografts with oncogene-specific [64Cu]chelator-peptide nucleic acid-IGF1 analog radiohybridization probes. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 48: 1699-707. PMID 17909257 DOI: 10.2967/Jnumed.107.042499  0.347
2007 Zhang K, Aruva MR, Shanthly N, Cardi CA, Patel CA, Rattan S, Cesarone G, Wickstrom E, Thakur ML. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating peptide (PACAP) receptor specific peptide analogues for PET imaging of breast cancer: In vitro/in vivo evaluation. Regulatory Peptides. 144: 91-100. PMID 17727979 DOI: 10.1016/J.Regpep.2007.06.008  0.349
2007 Yakubov LA, Rogachev VA, Likhacheva AC, Bogachev SS, Sebeleva TE, Shilov AG, Baiborodin SI, Petrova NA, Mechetina LV, Shurdov MA, Wickstrom E. Natural human gene correction by small extracellular genomic DNA fragments. Cell Cycle (Georgetown, Tex.). 6: 2293-301. PMID 17703110 DOI: 10.4161/Cc.6.18.4729  0.318
2007 Chakrabarti A, Zhang K, Aruva MR, Cardi CA, Opitz AW, Wagner NJ, Thakur ML, Wickstrom E. Radiohybridization PET imaging of KRAS G12D mRNA expression in human pancreas cancer xenografts with [(64)Cu]DO3A-peptide nucleic acid-peptide nanoparticles. Cancer Biology & Therapy. 6: 948-56. PMID 17611392 DOI: 10.4161/Cbt.6.6.4191  0.389
2007 Tian X, Chakrabarti A, Amirkhanov N, Aruva MR, Zhang K, Cardi CA, Lai S, Thakur ML, Wickstrom E. Receptor-mediated internalization of chelator-PNA-peptide hybridization probes for radioimaging or magnetic resonance imaging of oncogene mRNAs in tumours. Biochemical Society Transactions. 35: 72-6. PMID 17233604 DOI: 10.1042/Bst0350072  0.373
2007 Shao N, Lu S, Wickstrom E, Panchapakesan B. Integrated molecular targeting of IGF1R and HER2 surface receptors and destruction of breast cancer cells using single wall carbon nanotubes Nanotechnology. 18. DOI: 10.1088/0957-4484/18/31/315101  0.325
2006 Cesarone G, Garofalo C, Abrams MT, Igoucheva O, Alexeev V, Yoon K, Surmacz E, Wickstrom E. RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells. Journal of Cellular Biochemistry. 98: 440-50. PMID 16440325 DOI: 10.1002/Jcb.20817  0.322
2005 Efimov VA, Chakhmakhcheva OG, Wickstrom E. Synthesis and application of negatively charged PNA analogues. Nucleosides, Nucleotides & Nucleic Acids. 24: 1853-74. PMID 16438053 DOI: 10.1080/15257770500268830  0.305
2005 Tian X, Chakrabarti A, Amirkhanov NV, Aruva MR, Zhang K, Mathew B, Cardi C, Qin W, Sauter ER, Thakur ML, Wickstrom E. External imaging of CCND1, MYC, and KRAS oncogene mRNAs with tumor-targeted radionuclide-PNA-peptide chimeras. Annals of the New York Academy of Sciences. 1059: 106-44. PMID 16382049 DOI: 10.1196/Annals.1339.038  0.369
2005 Tian X, Aruva MR, Wolfe HR, Qin W, Sauter ER, Thakur ML, Waldman SA, Wickstrom E. Tumor-targeting peptide-PNA-peptide chimeras for imaging overexpressed oncogene mRNAs. Nucleosides, Nucleotides & Nucleic Acids. 24: 1085-91. PMID 16248097 DOI: 10.1081/Ncn-200059177  0.365
2005 Amirkhanov NV, Wickstrom E. Synthesis of novel polydiamidopropanoate dendrimer PNA-peptide chimeras for non-invasive magnetic resonance imaging of cancer. Nucleosides, Nucleotides & Nucleic Acids. 24: 423-6. PMID 16247963 DOI: 10.1081/Ncn-200059955  0.333
2005 Chakrabarti A, Aruva MR, Sajankila SP, Thakur ML, Wickstrom E. Synthesis of novel peptide nucleic acid-peptide chimera for non-invasive imaging of cancer. Nucleosides, Nucleotides & Nucleic Acids. 24: 409-14. PMID 16247960 DOI: 10.1081/Ncn-200061865  0.355
2005 Tian X, Aruva MR, Qin W, Zhu W, Sauter ER, Thakur ML, Wickstrom E. Noninvasive molecular imaging of MYC mRNA expression in human breast cancer xenografts with a [99mTc]peptide-peptide nucleic acid-peptide chimera. Bioconjugate Chemistry. 16: 70-9. PMID 15656577 DOI: 10.1021/Bc0497923  0.377
2005 Panchapakesan B, Cesarone G, Liu S, Teker K, Wickstrom E. Single-wall carbon nanotubes with adsorbed antibodies detect live breast cancer cells Nanobiotechnology. 1: 353-360. DOI: 10.1385/Nbt:1:4:353  0.308
2004 Wickstrom E, Choob M, Urtishak KA, Tian X, Sternheim N, Talbot S, Archdeacon J, Efimov VA, Farber SA. Sequence specificity of alternating hydroyprolyl/phosphono peptide nucleic acids against zebrafish embryo mRNAs. Journal of Drug Targeting. 12: 363-72. PMID 15545086 DOI: 10.1080/10611860412331285242  0.335
2003 Tian X, Aruva MR, Rao PS, Qin W, Read P, Sauter ER, Thakur ML, Wickstrom E. Imaging oncogene expression. Annals of the New York Academy of Sciences. 1002: 165-88. PMID 14751834 DOI: 10.1196/Annals.1281.015  0.381
2003 Vorobjev PE, Smith JB, Pyshnaya IA, Levina AS, Zarytova VF, Wickstrom E. Site-specific cleavage of RNA and DNA by complementary DNA--bleomycin A5 conjugates. Bioconjugate Chemistry. 14: 1307-13. PMID 14624648 DOI: 10.1021/Bc034148U  0.311
2003 Urtishak KA, Choob M, Tian X, Sternheim N, Talbot WS, Wickstrom E, Farber SA. Targeted gene knockdown in zebrafish using negatively charged peptide nucleic acid mimics. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 228: 405-13. PMID 14579379 DOI: 10.1002/Dvdy.10394  0.328
2003 Wickstrom E, Thakur ML, Sauter ER. Receptor-specific targeting with complementary peptide nucleic acids conjugated to peptide analogs and radionuclides Letters in Peptide Science. 10: 191-214. DOI: 10.1007/S10989-004-4917-7  0.386
2002 Wickstrom E, Sauter E, Tian X, Rao S, Quin W, Thakur M. Radiolabeled PNAs for imaging gene expression Brazilian Archives of Biology and Technology. 45: 57-59. DOI: 10.1590/S1516-89132002000500008  0.371
2002 Wickstrom E, Tian X, Rao PS, Thakur ML, Qin W, Sauter ER. Oncogene mRNA imaging with 99mTc-chelator-PNA-peptides Russian Chemical Bulletin. 51: 1083-1099. DOI: 10.1023/A:1020985420948  0.373
1999 Smith JB, Wickstrom E. Preclinical antisense DNA therapy of cancer in mice Methods in Enzymology. 314: 537-580. PMID 10565038 DOI: 10.1016/S0076-6879(99)14128-4  0.314
1997 Basu S, Wickstrom E. Synthesis and characterization of a peptide nucleic acid conjugated to a D-peptide analog of insulin-like growth factor 1 for increased cellular uptake Bioconjugate Chemistry. 8: 481-488. PMID 9258444 DOI: 10.1021/Bc9700650  0.37
1991 Ho PT, Ishiguro K, Wickstrom E, Sartorelli AC. Non-sequence-specific inhibition of transferrin receptor expression in HL-60 leukemia cells by phosphorothioate oligodeoxynucleotides Antisense Research and Development. 1: 329-342. PMID 1821654 DOI: 10.1089/Ard.1991.1.329  0.328
1988 Wickstrom EL, Bacon TA, Gonzalez A, Freeman DL, Lyman GH, Wickstrom E. Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA. Proceedings of the National Academy of Sciences of the United States of America. 85: 1028-32. PMID 3277186 DOI: 10.1073/Pnas.85.4.1028  0.307
1974 Wickstrom E, Tinoco I. The stability of RNA hairpin loops containing A–U–G: An–U–G–Um Biopolymers. 13: 2367-2383. PMID 4429788 DOI: 10.1002/Bip.1974.360131116  0.48
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