☰

A-Lien Lu - Publications

Affiliations: 
Biochemistry University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Biochemistry
Tree Info Similar researchers PubMed Report error

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hwang BJ, Gonzales R, Corzine S, Stenson E, Pidugu L, Lu AL. DNA binding by the Rad9A subunit of the Rad9-Rad1-Hus1 complex. Plos One. 17: e0272645. PMID 35939452 DOI: 10.1371/journal.pone.0272645  0.461
2022 Gupta A, Hwang BJ, Benyamien-Roufaeil D, Jain S, Liu S, Gonzales R, Brown RA, Zalzman M, Lu AL. Mammalian MutY Homolog (MYH or MUTYH) is Critical for Telomere Integrity under Oxidative Stress. Obm Geriatrics. 6. PMID 35812693 DOI: 10.21926/obm.geriatr.2202196  0.324
2020 Tan J, Wang X, Hwang BJ, Gonzales R, Konen O, Lan L, Lu AL. An ordered assembly of MYH glycosylase, SIRT6 protein deacetylase, and Rad9-Rad1-Hus1 checkpoint clamp at oxidatively damaged telomeres. Aging. 12. PMID 32991318 DOI: 10.18632/aging.103934  0.362
2015 Hwang BJ, Jin J, Gao Y, Shi G, Madabushi A, Yan A, Guan X, Zalzman M, Nakajima S, Lan L, Lu AL. SIRT6 protein deacetylase interacts with MYH DNA glycosylase, APE1 endonuclease, and Rad9-Rad1-Hus1 checkpoint clamp. Bmc Molecular Biology. 16: 12. PMID 26063178 DOI: 10.1186/S12867-015-0041-9  0.518
2015 Hwang BJ, Jin J, Gunther R, Madabushi A, Shi G, Wilson GM, Lu AL. Association of the Rad9-Rad1-Hus1 checkpoint clamp with MYH DNA glycosylase and DNA. Dna Repair. 31: 80-90. PMID 26021743 DOI: 10.1016/J.Dnarep.2015.05.004  0.482
2015 Lim PX, Patel DR, Poisson KE, Basuita M, Tsai C, Lyndaker AM, Hwang BJ, Lu AL, Weiss RS. Genome Protection by the 9-1-1 Complex Subunit HUS1 Requires Clamp Formation, DNA Contacts, and ATR Signaling-independent Effector Functions. The Journal of Biological Chemistry. 290: 14826-40. PMID 25911100 DOI: 10.1074/Jbc.M114.630640  0.493
2014 Jin J, Hwang BJ, Chang PW, Toth EA, Lu AL. Interaction of apurinic/apyrimidinic endonuclease 2 (Apn2) with Myh1 DNA glycosylase in fission yeast. Dna Repair. 15: 1-10. PMID 24559510 DOI: 10.1016/J.Dnarep.2014.01.001  0.523
2014 Hwang BJ, Shi G, Lu AL. Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage. Dna Repair. 13: 10-21. PMID 24315136 DOI: 10.1016/J.Dnarep.2013.10.011  0.464
2013 Luncsford PJ, Manvilla BA, Patterson DN, Malik SS, Jin J, Hwang BJ, Gunther R, Kalvakolanu S, Lipinski LJ, Yuan W, Lu W, Drohat AC, Lu AL, Toth EA. Coordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions. Dna Repair. 12: 1043-52. PMID 24209961 DOI: 10.1016/J.Dnarep.2013.09.007  0.436
2013 Madabushi A, Hwang BJ, Jin J, Lu AL. Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase. The Biochemical Journal. 456: 89-98. PMID 23952905 DOI: 10.1042/Bj20130670  0.524
2011 Chang DY, Shi G, Durand-Dubief M, Ekwall K, Lu AL. The role of MutY homolog (Myh1) in controlling the histone deacetylase Hst4 in the fission yeast Schizosaccharomyces pombe. Journal of Molecular Biology. 405: 653-65. PMID 21110984 DOI: 10.1016/J.Jmb.2010.11.037  0.467
2011 Madabushi A, Gunther R, Lu A. HUS1 (HUS1 checkpoint homolog (S. pombe)) Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/45024  0.41
2010 Luncsford PJ, Chang DY, Shi G, Bernstein J, Madabushi A, Patterson DN, Lu AL, Toth EA. A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions. Journal of Molecular Biology. 403: 351-70. PMID 20816984 DOI: 10.1016/J.Jmb.2010.08.045  0.502
2010 Bai H, Madabushi A, Guan X, Lu AL. Interaction between human mismatch repair recognition proteins and checkpoint sensor Rad9-Rad1-Hus1. Dna Repair. 9: 478-87. PMID 20188637 DOI: 10.1016/J.Dnarep.2010.01.011  0.489
2009 Chang P, Madabushi A, Lu A. Insights into the role of Val45 and Gln182 of Escherichia coli MutY in DNA substrate binding and specificity Bmc Biochemistry. 10: 19-19. PMID 19523222 DOI: 10.1186/1471-2091-10-19  0.485
2008 Leung HY, Yung LH, Poon CH, Shi G, Lu AL, Leung LK. Genistein protects against polycyclic aromatic hydrocarbon-induced oxidative DNA damage in non-cancerous breast cells MCF-10A. The British Journal of Nutrition. 101: 257-62. PMID 18570695 DOI: 10.1017/S0007114508998457  0.356
2007 Guan X, Madabushi A, Chang DY, Fitzgerald ME, Shi G, Drohat AC, Lu AL. The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase. Nucleic Acids Research. 35: 6207-18. PMID 17855402 DOI: 10.1093/Nar/Gkm678  0.515
2007 Guan X, Bai H, Shi G, Theriot CA, Hazra TK, Mitra S, Lu AL. The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates NEIL1 glycosylase. Nucleic Acids Research. 35: 2463-72. PMID 17395641 DOI: 10.1093/Nar/Gkm075  0.489
2007 Bai H, Lu A. Physical and Functional Interactions between Escherichia coli MutY Glycosylase and Mismatch Repair Protein MutS Journal of Bacteriology. 189: 902-910. PMID 17114250 DOI: 10.1128/Jb.01513-06  0.533
2007 Bai H, Grist S, Gardner J, Suthers G, Wilson TM, Lu AL. Functional characterization of human MutY homolog (hMYH) missense mutation (R231L) that is linked with hMYH-associated polyposis. Cancer Letters. 250: 74-81. PMID 17081686 DOI: 10.1016/J.Canlet.2006.09.016  0.443
2006 Shi G, Chang DY, Cheng CC, Guan X, Venclovas C, Lu AL. Physical and functional interactions between MutY glycosylase homologue (MYH) and checkpoint proteins Rad9-Rad1-Hus1. The Biochemical Journal. 400: 53-62. PMID 16879101 DOI: 10.1042/Bj20060774  0.423
2006 Lu A, Bai H, Shi G, Chang D. MutY and MutY homologs (MYH) in genome maintenance. Frontiers in Bioscience. 11: 3062. PMID 16720376 DOI: 10.2741/2033  0.497
2006 Lu AL, Lee CY, Li L, Li X. Physical and functional interactions between Escherichia coli MutY and endonuclease VIII. The Biochemical Journal. 393: 381-7. PMID 16201966 DOI: 10.1042/Bj20051133  0.549
2005 Bai H, Jones S, Guan X, Wilson TM, Sampson JR, Cheadle JP, Lu AL. Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis. Nucleic Acids Research. 33: 597-604. PMID 15673720 DOI: 10.1093/Nar/Gki209  0.461
2005 Lu AL, Clark S, Modrich P. Methyl-directed repair of DNA base-pair mismatches in vitro. 1983 Dna Repair. 4: 134-138; discussion . PMID 15533843 DOI: 10.1016/J.Dnarep.2004.07.003  0.343
2004 Chang DY, Lu AL. Interaction of checkpoint proteins Hus1/Rad1/Rad9 with DNA base excision repair enzyme MutY homolog in fission yeast, Schizosaccharomyces pombe. The Journal of Biological Chemistry. 280: 408-17. PMID 15533944 DOI: 10.1074/jbc.M406800200  0.418
2004 Lee CY, Bai H, Houle R, Wilson GM, Lu AL. An Escherichia coli MutY mutant without the six-helix barrel domain is a dimer in solution and assembles cooperatively into multisubunit complexes with DNA. The Journal of Biological Chemistry. 279: 52653-63. PMID 15456766 DOI: 10.1074/Jbc.M405271200  0.534
2003 Li L, Lu AL. The C-terminal domain of Escherichia coli MutY is involved in DNA binding and glycosylase activities. Nucleic Acids Research. 31: 3038-49. PMID 12799430 DOI: 10.1093/Nar/Gkg434  0.483
2003 Lu AL, Wright PM. Characterization of an Escherichia coli mutant MutY with a cysteine to alanine mutation at the iron-sulfur cluster domain. Biochemistry. 42: 3742-50. PMID 12667065 DOI: 10.1021/Bi0269198  0.325
2002 Chang D, Lu A. Functional interaction of MutY homolog with proliferating cell nuclear antigen in fission yeast, Schizosaccharomyces pombe. Journal of Biological Chemistry. 277: 11853-11858. PMID 11805113 DOI: 10.1074/Jbc.M111739200  0.443
2002 Gu Y, Parker A, Wilson TM, Bai H, Chang DY, Lu AL. Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6. The Journal of Biological Chemistry. 277: 11135-42. PMID 11801590 DOI: 10.1074/Jbc.M108618200  0.511
2001 Lu AL, Li X, Gu Y, Wright PM, Chang DY. Repair of oxidative DNA damage: Mechanisms and functions Cell Biochemistry and Biophysics. 35: 141-170. PMID 11892789 DOI: 10.1385/Cbb:35:2:141  0.501
2001 Li X, Lu AL. Molecular cloning and functional analysis of the MutY homolog of Deinococcus radiodurans. Journal of Bacteriology. 183: 6151-8. PMID 11591657 DOI: 10.1128/Jb.183.21.6151-6158.2001  0.509
2001 Gu Y, Lu A. Differential DNA recognition and glycosylase activity of the native human MutY homolog (hMYH) and recombinant hMYH expressed in bacteria Nucleic Acids Research. 29: 2666-2674. PMID 11410677 DOI: 10.1093/Nar/29.12.2666  0.513
2001 Li X, Lu AL. Intact MutY and its catalytic domain differentially contact with A/8-oxoG-containing DNA. Nucleic Acids Research. 28: 4593-603. PMID 11095667 DOI: 10.1093/Nar/28.23.4593  0.5
2001 Parker A, Gu Y, Mahoney W, Lee S, Singh KK, Lu A. Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair. Journal of Biological Chemistry. 276: 5547-5555. PMID 11092888 DOI: 10.1074/Jbc.M008463200  0.455
2000 Lu AL. Repair of A/G and A/8-oxoG mismatches by MutY adenine DNA glycosylase Methods in Molecular Biology (Clifton, N.J.). 152: 3-16. PMID 10957964 DOI: 10.1385/1-59259-068-3:3  0.511
2000 Parker A, Gu Y, Lu A. Purification and characterization of a mammalian homolog of Escherichia coli MutY mismatch repair protein from calf liver mitochondria Nucleic Acids Research. 28: 3206-3215. PMID 10954587 DOI: 10.1093/Nar/28.17.3206  0.462
2000 Li X, Wright PM, Lu AL. The C-terminal domain of MutY glycosylase determines the 7,8-dihydro-8- oxo-guanine specificity and is crucial for mutation avoidance Journal of Biological Chemistry. 275: 8448-8455. PMID 10722679 DOI: 10.1074/Jbc.275.12.8448  0.559
1999 Wright PM, Yu J, Cillo J, Lu AL. The active site of the Escherichia coli MutY DNA adenine glycosylase Journal of Biological Chemistry. 274: 29011-29018. PMID 10506150 DOI: 10.1074/Jbc.274.41.29011  0.544
1998 Lu A, Fawcett WP. Characterization of the Recombinant MutY Homolog, an Adenine DNA Glycosylase, from Yeast Schizosaccharomyces pombe Journal of Biological Chemistry. 273: 25098-25105. PMID 9737967 DOI: 10.1074/Jbc.273.39.25098  0.576
1997 Laufs S, Lu A, Arrell K, Carstens EB. Autographa californica nuclear polyhedrosis virus p143 gene product is a DNA-binding protein Virology. 228: 98-106. PMID 9024814 DOI: 10.1006/Viro.1996.8361  0.32
1996 Gogos A, Cillo J, Clarke ND, Lu AL. Specific recognition of A/G and A/7,8-dihydro-8-oxoguanine (8-oxoG) mismatches by Escherichia coli MutY: removal of the C-terminal domain preferentially affects A/8-oxoG recognition. Biochemistry. 35: 16665-71. PMID 8988002 DOI: 10.1021/Bi960843W  0.552
1996 Lu AL, Yuen DS, Cillo J. Catalytic mechanism and DNA substrate recognition of Escherichia coli MutY protein. The Journal of Biological Chemistry. 271: 24138-43. PMID 8798653 DOI: 10.1074/Jbc.271.39.24138  0.553
1996 Pellock BJ, Lu A, Meagher RB, Weise MJ, Miller LK. Sequence, function, and phylogenetic analysis of an ascovirus DNA polymerase gene. Virology. 216: 146-57. PMID 8614981 DOI: 10.1006/viro.1996.0041  0.373
1995 Fronticelli C, Sanna MT, Perez-Alvarado GC, Karavitis M, Lu A, Brinigar WS. Allosteric modulation by tertiary structure in mammalian hemoglobins. Introduction of the functional characteristics of bovine hemoglobin into human hemoglobin by five amino acid substitutions. Journal of Biological Chemistry. 270: 30588-30592. PMID 8530494 DOI: 10.1074/Jbc.270.51.30588  0.32
1995 Lu AL, Tsai-Wu JJ, Cillo J. DNA determinants and substrate specificities of Escherichia coli MutY. The Journal of Biological Chemistry. 270: 23582-8. PMID 7559523 DOI: 10.1074/Jbc.270.40.23582  0.446
1994 Tsai-Wu J, Lu A. Escherichia coli mutY-dependent mismatch repair involves DNA polymerase I and a short repair tract. Molecular Genetics and Genomics. 244: 444-450. PMID 8078471 DOI: 10.1007/Bf00286698  0.514
1993 Desiraju V, Shanabruch WG, Lu A. Nucleotide sequence of the Salmonella typhimurium mutB gene, the homolog of Escherichia coli mutY. Journal of Bacteriology. 175: 541-543. PMID 8419300 DOI: 10.1128/Jb.175.2.541-543.1993  0.357
1992 Lu A, Hsu I. Detection of single DNA base mutations with mismatch repair enzymes. Genomics. 14: 249-255. PMID 1427840 DOI: 10.1016/S0888-7543(05)80213-7  0.524
1992 Tsai-Wu J, Liu H, Lu A. Escherichia coli MutY protein has both N-glycosylase and apurinic/apyrimidinic endonuclease activities on A.C and A.G mispairs. Proceedings of the National Academy of Sciences of the United States of America. 89: 8779-8783. PMID 1382298 DOI: 10.1073/Pnas.89.18.8779  0.468
1991 Tsai-Wu J, Radicella JP, Lu A. Nucleotide sequence of the Escherichia coli micA gene required for A/G-specific mismatch repair: identity of micA and mutY. Journal of Bacteriology. 173: 1902-1910. PMID 2001994 DOI: 10.1128/Jb.173.6.1902-1910.1991  0.493
1991 Lu A, Carstens EB. Nucleotide sequence of a gene essential for viral DNA replication in the baculovirus Autographa californica nuclear polyhedrosis virus Virology. 181: 336-347. PMID 1994581 DOI: 10.1016/0042-6822(91)90500-B  0.32
1991 Chang D, Lu A. Base mismatch-specific endonuclease activity in extracts from Saccharomyces cerevisiae. Nucleic Acids Research. 19: 4761-4766. PMID 1891366 DOI: 10.1093/Nar/19.17.4761  0.464
1990 Carstens EB, Lu A. Nucleotide sequence and transcriptional analysis of the HindIII P region of a temperature-sensitive mutant of Autographa californica nuclear polyhedrosis virus Journal of General Virology. 71: 3035-3040. PMID 2273394 DOI: 10.1099/0022-1317-71-12-3035  0.315
1987 Lu AL. Influence of GATC sequences on Escherichia coli DNA mismatch repair in vitro Journal of Bacteriology. 169: 1254-1259. PMID 3029029 DOI: 10.1128/Jb.169.3.1254-1259.1987  0.433
Show low-probability matches.