Todd A. Lydic, Ph.D. - Publications

Affiliations: 
2012 Physiology Michigan State University, East Lansing, MI 
Area:
Physiology Biology, Analytical Chemistry, Biochemistry

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Dorweiler TF, Singh A, Ganju A, Lydic TA, Glazer LC, Kolesnick RN, Busik JV. Diabetic retinopathy is a ceramidopathy reversible by anti-ceramide immunotherapy. Cell Metabolism. PMID 38718792 DOI: 10.1016/j.cmet.2024.04.013  0.757
2024 Kostina A, Lewis-Israeli YR, Abdelhamid M, Gabalski MA, Kiselev A, Volmert BD, Lankerd H, Huang AR, Wasserman AH, Lydic T, Chan C, Park S, Olomu I, Aguirre A. ER stress and lipid imbalance drive diabetic embryonic cardiomyopathy in an organoid model of human heart development. Stem Cell Reports. PMID 38335962 DOI: 10.1016/j.stemcr.2024.01.003  0.445
2024 Ahmad Z, Singh S, Lee TJ, Sharma A, Lydic TA, Giri S, Kumar A. Untargeted and temporal analysis of retinal lipidome in bacterial endophthalmitis. Prostaglandins & Other Lipid Mediators. 106806. PMID 38185280 DOI: 10.1016/j.prostaglandins.2023.106806  0.365
2023 Kostina A, Lewis-Israeli YR, Abdelhamid M, Gabalski MA, Volmert BD, Lankerd H, Huang AR, Wasserman AH, Lydic T, Chan C, Olomu I, Aguirre A. ER stress and lipid imbalance drive embryonic cardiomyopathy in a human heart organoid model of pregestational diabetes. Biorxiv : the Preprint Server For Biology. PMID 37333095 DOI: 10.1101/2023.06.07.544081  0.39
2023 Busik JV, Decot H, Lin AB, Lydic TA. Untargeted Analysis of Lipids Containing Very Long Chain Fatty Acids in Retina and Retinal Tight Junctions. Methods in Molecular Biology (Clifton, N.J.). 2625: 269-290. PMID 36653650 DOI: 10.1007/978-1-0716-2966-6_23  0.741
2022 Lydic TA, Busik JV. Diabetes Retinopathy: New Ways to Detect and Treat. Methods in Molecular Biology (Clifton, N.J.). 2592: 89-100. PMID 36507987 DOI: 10.1007/978-1-0716-2807-2_6  0.745
2021 Hammer SS, Vieira CP, McFarland D, Sandler M, Levitsky Y, Dorweiler TF, Lydic TA, Asare-Bediako B, Adu-Agyeiwaah Y, Sielski MS, Dupont M, Longhini AL, Li Calzi S, Chakraborty D, Seigel GM, et al. Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction. Diabetologia. PMID 33770194 DOI: 10.1007/s00125-021-05431-5  0.734
2020 Vieira CP, Fortmann SD, Hossain M, Longhini AL, Hammer SS, Asare-Bediako B, Crossman DK, Sielski MS, Adu-Agyeiwaah Y, Dupont M, Floyd JL, Li Calzi S, Lydic T, Welner RS, Blanchard GJ, et al. Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes. Jci Insight. 5. PMID 32641586 DOI: 10.1172/Jci.Insight.137230  0.772
2020 Truong NTT, Lydic TA, Bazil JN, Suryadevara A, Olson LK. Regulation of lipid metabolism in pancreatic beta cells by interferon gamma: A link to anti-viral function. Cytokine. 133: 155147. PMID 32492632 DOI: 10.1016/J.Cyto.2020.155147  0.408
2020 Levitsky Y, Hammer SS, Fisher KP, Huang C, Gentles TL, Pegouske DJ, Xi C, Lydic TA, Busik JV, Proshlyakov DA. Mitochondrial Ceramide Effects on the Retinal Pigment Epithelium in Diabetes. International Journal of Molecular Sciences. 21. PMID 32481596 DOI: 10.3390/Ijms21113830  0.742
2020 Doskey CM, Fader KA, Nault R, Lydic T, Matthews J, Potter D, Sharratt B, Williams K, Zacharewski T. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters hepatic polyunsaturated fatty acid metabolism and eicosanoid biosynthesis in female Sprague-Dawley rats. Toxicology and Applied Pharmacology. 115034. PMID 32387183 DOI: 10.1016/J.Taap.2020.115034  0.396
2020 Vieira CP, Fortmann SD, Longhini AL, Lydic TA, Busik JV, Grant MB. 333-OR: DMHCA Reduces the Development of Diabetic Retinopathy (DR) in db/db Mice by Lowering Cholesterol Levels and Altering the Transcriptomic Profile of Hematopoietic Stem Cells Diabetes. 69. DOI: 10.2337/Db20-333-Or  0.705
2019 Paul A, Lydic TA, Hogan R, Goo YH. Cholesterol Acceptors Regulate the Lipidome of Macrophage Foam Cells. International Journal of Molecular Sciences. 20. PMID 31382484 DOI: 10.3390/Ijms20153784  0.322
2019 Delekta PC, Lydic TA, Hammer ND. Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids. Journal of Visualized Experiments : Jove. PMID 31157784 DOI: 10.3791/59538  0.391
2019 Machacek M, Saunders H, Zhang Z, Tan EP, Li J, Li T, Villar MT, Artigues A, Lydic T, Cork G, Slawson C, Fields PE. Elevated O-GlcNAcylation enhances pro-inflammatory Th17 function by altering the intracellular lipid microenvironment. The Journal of Biological Chemistry. PMID 31010828 DOI: 10.1074/Jbc.Ra119.008373  0.322
2019 PEGOUSKE D, LEVITSKY Y, HAMMER S, LYDIC TA, MUCHNIK A, PROSHLYAKOV DA, BUSIK JV. 583-P: Increase in Mitochondrial Ceramide Contributes to Diabetes-Induced Retinal Endothelial Cell Damage Diabetes. 68: 583-P. DOI: 10.2337/Db19-583-P  0.752
2018 Agbaga MG, Merriman DK, Brush RS, Lydic TA, Conley SM, Naash MI, Jackson S, Woods AS, Reid GE, Busik JV, Anderson RE. Differential Composition of DHA and Very Long Chain PUFAs in Rod and Cone Photoreceptors. Journal of Lipid Research. PMID 29986998 DOI: 10.1194/Jlr.M082495  0.698
2018 Delekta PC, Shook JC, Lydic TA, Mulks MH, Hammer ND. utilizes host-derived lipoprotein particles as sources of exogenous fatty acids. Journal of Bacteriology. PMID 29581406 DOI: 10.1128/Jb.00728-17  0.407
2018 Lydic TA, Goo YH. Lipidomics unveils the complexity of the lipidome in metabolic diseases. Clinical and Translational Medicine. 7: 4. PMID 29374337 DOI: 10.1186/S40169-018-0182-9  0.302
2018 Kady NM, Liu X, Lydic TA, Syed MH, Navitskaya S, Wang Q, Hammer SS, O'Reilly S, Huang C, Seregin SS, Amalfitano A, Chiodo VA, Boye SL, Hauswirth WW, Antonetti DA, et al. ELOVL4-Mediated Production of Very Long Chain Ceramides Stabilizes Tight Junctions and Prevents Diabetes-Induced Retinal Vascular Permeability. Diabetes. PMID 29362226 DOI: 10.2337/Db17-1034  0.777
2018 Goo Y, Lee I, Lydic TA, Bangru S, Saha P, Kalsotra A, Chan LC, Paul A. Abstract 447: Lipid Droplet Associated Hydrolase (LDAH) Impacts Oxysterol Metabolism and Prevents Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.447  0.339
2017 Hammer SS, Beli E, Kady N, Wang Q, Wood K, Lydic TA, Malek G, Saban DR, Wang XX, Hazra S, Levi M, Busik JV, Grant MB. The Mechanism of Diabetic Retinopathy Pathogenesis Unifying Key Lipid Regulators, Sirtuin 1 and Liver X Receptor. Ebiomedicine. PMID 28774737 DOI: 10.1016/J.Ebiom.2017.07.008  0.78
2017 Nault R, Fader KA, Lydic TA, Zacharewski TR. Lipidomic evaluation of aryl hydrocarbon receptor-mediated hepatic steatosis in male and female mice by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chemical Research in Toxicology. PMID 28238261 DOI: 10.1021/Acs.Chemrestox.6B00430  0.37
2016 Wang Q, Navitskaya S, Chakravarthy H, Huang C, Kady N, Lydic TA, Chen YE, Yin KJ, Powell FL, Martin PM, Grant MB, Busik JV. Dual Anti-Inflammatory and Anti-Angiogenic Action of miR-15a in Diabetic Retinopathy. Ebiomedicine. PMID 27531575 DOI: 10.1016/J.Ebiom.2016.08.013  0.668
2015 Lydic TA, Townsend S, Adda CG, Collins C, Mathivanan S, Reid GE. Rapid and comprehensive 'shotgun' lipidome profiling of colorectal cancer cell derived exosomes. Methods (San Diego, Calif.). PMID 25907253 DOI: 10.1016/J.Ymeth.2015.04.014  0.318
2015 Cai Y, Lydic TA, Turkette T, Reid GE, Olson LK. Impact of alogliptin and pioglitazone on lipid metabolism in islets of prediabetic and diabetic Zucker Diabetic Fatty rats. Biochemical Pharmacology. 95: 46-57. PMID 25801003 DOI: 10.1016/J.Bcp.2015.03.010  0.482
2014 Lydic TA, Busik JV, Reid GE. A monophasic extraction strategy for the simultaneous lipidome analysis of polar and nonpolar retina lipids. Journal of Lipid Research. 55: 1797-1809. PMID 24879804 DOI: 10.1194/Jlr.D050302  0.624
2014 Wang Q, Tikhonenko M, Bozack SN, Lydic TA, Yan L, Panchy NL, McSorley KM, Faber MS, Yan Y, Boulton ME, Grant MB, Busik JV. Changes in the daily rhythm of lipid metabolism in the diabetic retina. Plos One. 9: e95028. PMID 24736612 DOI: 10.1371/Journal.Pone.0095028  0.82
2014 Bennett LD, Brush RS, Chan M, Lydic TA, Reese K, Reid GE, Busik JV, Elliott MH, Anderson RE. Effect of reduced retinal VLC-PUFA on rod and cone photoreceptors. Investigative Ophthalmology & Visual Science. 55: 3150-7. PMID 24722693 DOI: 10.1167/Iovs.14-13995  0.693
2013 Chen W, Zhou H, Liu S, Fhaner CJ, Gross BC, Lydic TA, Reid GE. Altered lipid metabolism in residual white adipose tissues of Bscl2 deficient mice. Plos One. 8: e82526. PMID 24358199 DOI: 10.1371/Journal.Pone.0082526  0.413
2013 Sanjaya, Miller R, Durrett TP, Kosma DK, Lydic TA, Muthan B, Koo AJ, Bukhman YV, Reid GE, Howe GA, Ohlrogge J, Benning C. Altered lipid composition and enhanced nutritional value of Arabidopsis leaves following introduction of an algal diacylglycerol acyltransferase 2. The Plant Cell. 25: 677-93. PMID 23417035 DOI: 10.1105/Tpc.112.104752  0.313
2013 Tikhonenko M, Lydic TA, Opreanu M, Li Calzi S, Bozack S, McSorley KM, Sochacki AL, Faber MS, Hazra S, Duclos S, Guberski D, Reid GE, Grant MB, Busik JV. N-3 polyunsaturated Fatty acids prevent diabetic retinopathy by inhibition of retinal vascular damage and enhanced endothelial progenitor cell reparative function. Plos One. 8: e55177. PMID 23383097 DOI: 10.1371/Journal.Pone.0055177  0.782
2013 Chen W, Zhou H, Liu S, Fhaner CJ, Gross BC, Lydic TA, Reid GE. De novo lipogenesis and metabolic pathways of MUFA and PUFAs. Plos One. DOI: 10.1371/Journal.Pone.0082526.G001  0.302
2011 Opreanu M, Tikhonenko M, Bozack S, Lydic TA, Reid GE, McSorley KM, Sochacki A, Perez GI, Esselman WJ, Kern T, Kolesnick R, Grant MB, Busik JV. The unconventional role of acid sphingomyelinase in regulation of retinal microangiopathy in diabetic human and animal models. Diabetes. 60: 2370-8. PMID 21771974 DOI: 10.2337/Db10-0550  0.786
2010 Griffitts J, Saunders D, Tesiram YA, Reid GE, Salih A, Liu S, Lydic TA, Busik JV, Kang JX, Towner RA. Non-mammalian fat-1 gene prevents neoplasia when introduced to a mouse hepatocarcinogenesis model: Omega-3 fatty acids prevent liver neoplasia. Biochimica Et Biophysica Acta. 1801: 1133-44. PMID 20620224 DOI: 10.1016/J.Bbalip.2010.06.008  0.641
2010 Opreanu M, Lydic TA, Reid GE, McSorley KM, Esselman WJ, Busik JV. Inhibition of cytokine signaling in human retinal endothelial cells through downregulation of sphingomyelinases by docosahexaenoic acid. Investigative Ophthalmology & Visual Science. 51: 3253-63. PMID 20071681 DOI: 10.1167/Iovs.09-4731  0.789
2010 Tikhonenko M, Lydic TA, Wang Y, Chen W, Opreanu M, Sochacki A, McSorley KM, Renis RL, Kern T, Jump DB, Reid GE, Busik JV. Remodeling of retinal Fatty acids in an animal model of diabetes: a decrease in long-chain polyunsaturated fatty acids is associated with a decrease in fatty acid elongases Elovl2 and Elovl4. Diabetes. 59: 219-27. PMID 19875612 DOI: 10.2337/Db09-0728  0.789
2010 Tikhonenko M, Lydic TA, Reid GE, Busik JV. Response to comment on: Tikhonenko et al. (2010) Remodeling of retinal fatty acids in an animal model of diabetes: A decrease in long-chain polyunsaturated fatty acids is associated with a decrease in fatty acid elongases Elovl2 and Elovl4. Diabetes;59:219-227 Diabetes. 59. DOI: 10.2337/Db10-0623  0.827
2009 Lydic TA, Renis R, Busik JV, Reid GE. Analysis of Retina and Erythrocyte Glycerophospholipid Alterations in a Rat Model of Type 1 Diabetes. Jala (Charlottesville, Va.). 14: 383-399. PMID 20161420 DOI: 10.1016/J.Jala.2009.07.003  0.769
2009 Busik JV, Reid GE, Lydic TA. Global analysis of retina lipids by complementary precursor ion and neutral loss mode tandem mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 579: 33-70. PMID 19763470 DOI: 10.1007/978-1-60761-322-0_3  0.653
2009 Kielczewski JL, Jarajapu YP, McFarland EL, Cai J, Afzal A, Li Calzi S, Chang KH, Lydic T, Shaw LC, Busik J, Hughes J, Cardounel AJ, Wilson K, Lyons TJ, Boulton ME, et al. Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. Circulation Research. 105: 897-905. PMID 19762684 DOI: 10.1161/Circresaha.109.199059  0.61
2009 Lydic TA, Busik JV, Esselman WJ, Reid GE. Complementary precursor ion and neutral loss scan mode tandem mass spectrometry for the analysis of glycerophosphatidylethanolamine lipids from whole rat retina. Analytical and Bioanalytical Chemistry. 394: 267-75. PMID 19277613 DOI: 10.1007/S00216-009-2717-9  0.62
2003 Riekhof WR, Ruckle ME, Lydic TA, Sears BB, Benning C. The sulfolipids 2'-O-acyl-sulfoquinovosyldiacylglycerol and sulfoquinovosyldiacylglycerol are absent from a Chlamydomonas reinhardtii mutant deleted in SQD1. Plant Physiology. 133: 864-74. PMID 14500794 DOI: 10.1104/Pp.103.029249  0.359
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