Year |
Citation |
Score |
2015 |
Mendelsohn J, Prewett M, Rockwell P, Goldstein NI. CCR 20th anniversary commentary: a chimeric antibody, C225, inhibits EGFR activation and tumor growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 227-9. PMID 25593342 DOI: 10.1158/1078-0432.CCR-14-2491 |
1 |
|
2014 |
Figueiredo-Pereira ME, Rockwell P, Schmidt-Glenewinkel T, Serrano P. Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration. Frontiers in Molecular Neuroscience. 7: 104. PMID 25628533 DOI: 10.3389/fnmol.2014.00104 |
1 |
|
2013 |
Hao T, Rockwell P. Signaling through the vascular endothelial growth factor receptor VEGFR-2 protects hippocampal neurons from mitochondrial dysfunction and oxidative stress. Free Radical Biology & Medicine. 63: 421-31. PMID 23732519 DOI: 10.1016/j.freeradbiomed.2013.05.036 |
1 |
|
2012 |
Edelstein J, Rockwell P. Okadaic acid induces Akt hyperphosphorylation and an oxidative stress-mediated cell death in serum starved SK-N-SH human neuroblastoma cells that are augmented by rapamycin. Neuroscience Letters. 531: 74-9. PMID 23127854 DOI: 10.1016/j.neulet.2012.10.052 |
1 |
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2011 |
Edelstein J, Hao T, Cao Q, Morales L, Rockwell P. Crosstalk between VEGFR2 and muscarinic receptors regulates the mTOR pathway in serum starved SK-N-SH human neuroblastoma cells. Cellular Signalling. 23: 239-48. PMID 20851763 DOI: 10.1016/j.cellsig.2010.09.008 |
1 |
|
2008 |
Papa L, Rockwell P. Persistent mitochondrial dysfunction and oxidative stress hinder neuronal cell recovery from reversible proteasome inhibition. Apoptosis : An International Journal On Programmed Cell Death. 13: 588-99. PMID 18299995 DOI: 10.1007/s10495-008-0182-0 |
1 |
|
2008 |
Gomes E, Rockwell P. p38 MAPK as a negative regulator of VEGF/VEGFR2 signaling pathway in serum deprived human SK-N-SH neuroblastoma cells. Neuroscience Letters. 431: 95-100. PMID 18178312 DOI: 10.1016/j.neulet.2007.11.068 |
1 |
|
2008 |
Toschi A, Edelstein J, Rockwell P, Ohh M, Foster DA. HIF alpha expression in VHL-deficient renal cancer cells is dependent on phospholipase D. Oncogene. 27: 2746-53. PMID 17998935 DOI: 10.1038/sj.onc.1210927 |
1 |
|
2007 |
Gomes E, Papa L, Hao T, Rockwell P. The VEGFR2 and PKA pathways converge at MEK/ERK1/2 to promote survival in serum deprived neuronal cells. Molecular and Cellular Biochemistry. 305: 179-90. PMID 17646929 DOI: 10.1007/s11010-007-9542-2 |
1 |
|
2007 |
Papa L, Gomes E, Rockwell P. Reactive oxygen species induced by proteasome inhibition in neuronal cells mediate mitochondrial dysfunction and a caspase-independent cell death. Apoptosis : An International Journal On Programmed Cell Death. 12: 1389-405. PMID 17415663 DOI: 10.1007/s10495-007-0069-5 |
1 |
|
2006 |
Rodrik V, Gomes E, Hui L, Rockwell P, Foster DA. Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cells. Febs Letters. 580: 5647-52. PMID 16996503 DOI: 10.1016/j.febslet.2006.09.013 |
1 |
|
2004 |
Li Z, Arnaud L, Rockwell P, Figueiredo-Pereira ME. A single amino acid substitution in a proteasome subunit triggers aggregation of ubiquitinated proteins in stressed neuronal cells. Journal of Neurochemistry. 90: 19-28. PMID 15198663 DOI: 10.1111/j.1471-4159.2004.02456.x |
1 |
|
2004 |
Rockwell P, Martinez J, Papa L, Gomes E. Redox regulates COX-2 upregulation and cell death in the neuronal response to cadmium. Cellular Signalling. 16: 343-53. PMID 14687664 DOI: 10.1016/j.cellsig.2003.08.006 |
1 |
|
2002 |
Figueiredo-Pereira ME, Li Z, Jansen M, Rockwell P. N-acetylcysteine and celecoxib lessen cadmium cytotoxicity which is associated with cyclooxygenase-2 up-regulation in mouse neuronal cells. The Journal of Biological Chemistry. 277: 25283-9. PMID 11997384 DOI: 10.1074/jbc.M109145200 |
1 |
|
2001 |
Neuchrist C, Erovic BM, Handisurya A, Steiner GE, Rockwell P, Gedlicka C, Burian M. Vascular endothelial growth factor receptor 2 (VEGFR2) expression in squamous cell carcinomas of the head and neck Laryngoscope. 111: 1834-1841. PMID 11801954 |
1 |
|
2000 |
Rockwell P, Yuan H, Magnusson R, Figueiredo-Pereira ME. Proteasome inhibition in neuronal cells induces a proinflammatory response manifested by upregulation of cyclooxygenase-2, its accumulation as ubiquitin conjugates, and production of the prostaglandin PGE2 Archives of Biochemistry and Biophysics. 374: 325-333. PMID 10666314 DOI: 10.1006/abbi.1999.1646 |
1 |
|
1998 |
Witte L, Hicklin DJ, Zhu Z, Pytowski B, Kotanides H, Rockwell P, Böhlen P. Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy Cancer and Metastasis Reviews. 17: 155-161. PMID 9770111 DOI: 10.1023/A:1006094117427 |
1 |
|
1998 |
Zhu Z, Rockwell P, Lu D, Kotanides H, Pytowski B, Hicklin DJ, Bohlen P, Witte L. Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library Cancer Research. 58: 3209-3214. PMID 9699643 |
1 |
|
1997 |
Viloria Petit AM, Rak J, Hung MC, Rockwell P, Goldstein N, Fendly B, Kerbel RS. Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors American Journal of Pathology. 151: 1523-1530. PMID 9403702 |
1 |
|
1997 |
Skobe M, Rockwell P, Goldstein N, Vosseler S, Fusenig NE. Halting angiogenesis suppresses carcinoma cell invasion Nature Medicine. 3: 1222-1227. PMID 9359696 |
1 |
|
1997 |
Rockwell P, O'Connor WJ, King K, Goldstein NI, Zhang LM, Stein CA. Cell-surface perturbations of the epidermal growth factor and vascular endothelial growth factor receptors by phosphorothioate oligodeoxynucleotides. Proceedings of the National Academy of Sciences of the United States of America. 94: 6523-8. PMID 9177251 DOI: 10.1073/pnas.94.12.6523 |
1 |
|
1996 |
Prewett M, Rockwell P, Rockwell RF, Giorgio NA, Mendelsohn J, Scher HI, Goldstein NI. The biologic effects of C225, a chimeric monoclonal antibody to the EGFR, on human prostate carcinoma Journal of Immunotherapy. 19: 419-427. PMID 9041461 DOI: 10.1097/00002371-199611000-00006 |
1 |
|
1996 |
Gitay-Goren H, Cohen T, Tessler S, Sokerl S, Gengrinovitch S, Rockwell P, Klagsbrun M, Levi BZ, Neufeld G. Selective binding of VEGF121 to one of the three vascular endothelial growth factor receptors of vascular endothelial cells Journal of Biological Chemistry. 271: 5519-5523. PMID 8621410 |
1 |
|
1996 |
Carow CE, Levenstein M, Kaufmann SH, Chen J, Amin S, Rockwell P, Witte L, Borowitz MJ, Civin CI, Small D. Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias Blood. 87: 1089-1096. PMID 8562934 |
1 |
|
1996 |
Prewett M, Rockwell P, Rose C, Goldstein NI. Anti-tremor and cell cycle responses in KB celIs treated with a chimeric anti-EGFR monoclonal antibody in combination with cisplatin International Journal of Oncology. 9: 217-224. |
1 |
|
1996 |
Prewett M, Rockwell P, Rose C, Zuklys K, Goldstein NI. Altered cell cycle distribution and cyclin-CDK protein expression in A431 epidermoid carcinoma cells treated with doxorubicin and a chimeric monoclonal antibody to the epidermal growth factor receptor Molecular and Cellular Differentiation. 4: 167-186. |
1 |
|
1995 |
Goldstein NI, Prewett M, Zuklys K, Rockwell P, Mendelsohn J. Biological Efficacy of a Chimeric Antibody to the Epidermal Growth Factor Receptor in a Human Tumor Xenograft Model Clinical Cancer Research. 1: 1311-1318. PMID 9815926 |
1 |
|
1995 |
Rose C, Rockwell P, Yang JQ, Pytowski B, Goldstein NI. Isolation and characterization of a monoclonal antibody binding to the extracellular domain of the flk-2 tyrosine kinase receptor Hybridoma. 14: 453-459. PMID 8575794 |
1 |
|
1995 |
Gengrinovitch S, Greenberg SM, Cohen T, Gitay-Goren H, Rockwell P, Maione TE, Levi BZ, Neufeld G. Platelet factor-4 inhibits the mitogenic activity of VEGF121 and VEGF165 using several concurrent mechanisms Journal of Biological Chemistry. 270: 15059-15065. PMID 7797488 |
1 |
|
1995 |
Rockwell P, Goldstein NI. Role of protein tyrosine kinase receptors in cancer: Possibilities for therapeutic intervention Molecular and Cellular Differentiation. 3: 315-335. |
1 |
|
1995 |
Rockwell P, Neufeld G, Glassman A, Caron D, Goldstein N. In vitro neutralization of vascular endothelial growth factor activation of Flk-1 by a monoclonal antibody Molecular and Cellular Differentiation. 3: 91-109. |
1 |
|
1994 |
Tessler S, Rockwell P, Hicklin D, Cohen T, Levi BZ, Witte L, Lemischka IR, Neufeld G. Heparin modulates the interaction of VEGF165 with soluble and cell associated flk-1 receptors Journal of Biological Chemistry. 269: 12456-12461. PMID 8175651 |
1 |
|
1994 |
Small D, Levenstein M, Kim E, Carow C, Amin S, Rockwell P, Witte L, Burrow C, Ratajczak MZ, Gewirtz AM, Civin CI. STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells Proceedings of the National Academy of Sciences of the United States of America. 91: 459-463. PMID 7507245 |
1 |
|
1991 |
Rockwell P, Gottesman ME. An Escherichia coli rpoB mutation that inhibits transcription of catabolite-sensitive operons. Journal of Molecular Biology. 222: 189-96. PMID 1660071 DOI: 10.1016/0022-2836(91)90205-K |
1 |
|
1988 |
Rockwell P, Krakow JS. Effects of an anti-β monoclonal antibody on the interaction of the Escherichia coli RNA polymerase with the lac and TAC promoters Biochemistry. 27: 3512-3520. PMID 3291950 |
1 |
|
1985 |
Rockwell P, Beasley E, Krakow JS. Characterization of effects of anti-β and anti-β′ monoclonal antibodies on the activity of the RNA polymerase from Escherichia coli Biochemistry. 24: 3240-3245. PMID 3896308 |
1 |
|
1985 |
Rockwell P, Krakow JS. Effects of anti-beta and anti-beta' monoclonal antibodies on promoter binding and abortive initiation by the E. coli RNA polymerase Federation Proceedings. 44. |
1 |
|
1984 |
Rockwell P, Krakow JS. Effects of beta' and beta specific monoclonal antibodies on promoter utilization by the E. coli RNA polymerase Federation Proceedings. 43. |
1 |
|
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