Stephen C. Bunnell - Publications

Immunology Sackler School of Graduate Biomedical Sciences (Tufts University) 
Immunology, Cell Biology, Biochemistry

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Fray MA, Charpentier JC, Sylvain NR, Seminario MC, Bunnell SC. Vav2 lacks calcium entry-promoting scaffolding functions unique to Vav1 and inhibits T cell activation via Cdc42. Journal of Cell Science. PMID 31974114 DOI: 10.1242/jcs.238337  1
2018 Lewis JB, Scangarello FA, Murphy JM, Eidell KP, Sodipo MO, Ophir MJ, Sargeant R, Seminario MC, Bunnell SC. ADAP is an upstream regulator that precedes SLP-76 at sites of TCR engagement and stabilizes signaling microclusters. Journal of Cell Science. PMID 30305305 DOI: 10.1242/jcs.215517  0.44
2018 Kalantari P, Morales Y, Miller EA, Jaramillo LD, Ponichtera HE, Wuethrich MA, Cheong C, Seminario MC, Russo JM, Bunnell SC, Stadecker MJ. CD209a Synergizes with Dectin-2 and Mincle to Drive Severe Th17 Cell-Mediated Schistosome Egg-Induced Immunopathology. Cell Reports. 22: 1288-1300. PMID 29386115 DOI: 10.1016/j.celrep.2018.01.001  0.44
2014 Fray MA, Bunnell SC. p53 keeps bystanders at the gates. Immunity. 40: 633-5. PMID 24837097 DOI: 10.1016/j.immuni.2014.05.001  1
2014 Ponichtera HE, Shainheit MG, Liu BC, Raychowdhury R, Larkin BM, Russo JM, Salantes DB, Lai CQ, Parnell LD, Yun TJ, Cheong C, Bunnell SC, Hacohen N, Stadecker MJ. CD209a expression on dendritic cells is critical for the development of pathogenic Th17 cell responses in murine schistosomiasis. Journal of Immunology (Baltimore, Md. : 1950). 192: 4655-65. PMID 24729611 DOI: 10.4049/jimmunol.1400121  1
2014 Cruz-Orcutt N, Vacaflores A, Connolly SF, Bunnell SC, Houtman JC. Activated PLC-γ1 is catalytically induced at LAT but activated PLC-γ1 is localized at both LAT- and TCR-containing complexes. Cellular Signalling. 26: 797-805. PMID 24412752 DOI: 10.1016/j.cellsig.2013.12.022  1
2013 Ophir MJ, Liu BC, Bunnell SC. The N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms. The Journal of Cell Biology. 203: 1021-41. PMID 24368808 DOI: 10.1083/jcb.201305088  1
2012 Molano A, Huang Z, Marko MG, Azzi A, Wu D, Wang E, Kelly SL, Merrill AH, Bunnell SC, Meydani SN. Age-dependent changes in the sphingolipid composition of mouse CD4+ T cell membranes and immune synapses implicate glucosylceramides in age-related T cell dysfunction. Plos One. 7: e47650. PMID 23110086 DOI: 10.1371/journal.pone.0047650  1
2011 Sylvain NR, Nguyen K, Bunnell SC. Vav1-mediated scaffolding interactions stabilize SLP-76 microclusters and contribute to antigen-dependent T cell responses. Science Signaling. 4: ra14. PMID 21386095 DOI: 10.1126/scisignal.2001178  1
2010 Bunnell SC. Multiple microclusters: diverse compartments within the immune synapse. Current Topics in Microbiology and Immunology. 340: 123-54. PMID 19960312 DOI: 10.1007/978-3-642-03858-7_7  1
2009 Barr VA, Bunnell SC. Interference reflection microscopy. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 4.23. PMID 20013754 DOI: 10.1002/0471143030.cb0423s45  1
2009 Bunnell SC. A view to a kill: how ligand quality controls lethal hits. Immunity. 31: 531-3. PMID 19833082 DOI: 10.1016/j.immuni.2009.09.011  1
2009 Sacristán C, Schattgen SA, Berg LJ, Bunnell SC, Roy AL, Rosenstein Y. Characterization of a novel interaction between transcription factor TFII-I and the inducible tyrosine kinase in T cells. European Journal of Immunology. 39: 2584-95. PMID 19701889 DOI: 10.1002/eji.200839031  1
2009 Marko MG, Pang HJ, Ren Z, Azzi A, Huber BT, Bunnell SC, Meydani SN. Vitamin E reverses impaired linker for activation of T cells activation in T cells from aged C57BL/6 mice. The Journal of Nutrition. 139: 1192-7. PMID 19403707 DOI: 10.3945/jn.108.103416  1
2008 Nguyen K, Sylvain NR, Bunnell SC. T cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76. Immunity. 28: 810-21. PMID 18549800 DOI: 10.1016/j.immuni.2008.04.019  1
2008 Seminario MC, Bunnell SC. Signal initiation in T-cell receptor microclusters. Immunological Reviews. 221: 90-106. PMID 18275477 DOI: 10.1111/j.1600-065X.2008.00593.x  1
2007 Marko MG, Ahmed T, Bunnell SC, Wu D, Chung H, Huber BT, Meydani SN. Age-associated decline in effective immune synapse formation of CD4(+) T cells is reversed by vitamin E supplementation. Journal of Immunology (Baltimore, Md. : 1950). 178: 1443-9. PMID 17237392  1
2007 Morley SC, Sung J, Sun GP, Martelli MP, Bunnell SC, Bierer BE. Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells. Molecular Immunology. 44: 2469-80. PMID 17178161 DOI: 10.1016/j.molimm.2006.09.024  1
2006 Bunnell SC, Singer AL, Hong DI, Jacque BH, Jordan MS, Seminario MC, Barr VA, Koretzky GA, Samelson LE. Persistence of cooperatively stabilized signaling clusters drives T-cell activation. Molecular and Cellular Biology. 26: 7155-66. PMID 16980618 DOI: 10.1128/MCB.00507-06  1
2006 Barr VA, Balagopalan L, Barda-Saad M, Polishchuk R, Boukari H, Bunnell SC, Bernot KM, Toda Y, Nossal R, Samelson LE. T-cell antigen receptor-induced signaling complexes: internalization via a cholesterol-dependent endocytic pathway. Traffic (Copenhagen, Denmark). 7: 1143-62. PMID 16919152 DOI: 10.1111/j.1600-0854.2006.00464.x  1
2006 Zipfel PA, Bunnell SC, Witherow DS, Gu JJ, Chislock EM, Ring C, Pendergast AM. Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling. Current Biology : Cb. 16: 35-46. PMID 16401422 DOI: 10.1016/j.cub.2005.12.024  1
2005 Barda-Saad M, Braiman A, Titerence R, Bunnell SC, Barr VA, Samelson LE. Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton. Nature Immunology. 6: 80-9. PMID 15558067 DOI: 10.1038/ni1143  1
2004 Seminario MC, Precht P, Bunnell SC, Warren SE, Morris CM, Taub D, Wange RL. PTEN permits acute increases in D3-phosphoinositide levels following TCR stimulation but inhibits distal signaling events by reducing the basal activity of Akt. European Journal of Immunology. 34: 3165-75. PMID 15468057 DOI: 10.1002/eji.200425206  1
2004 Singer AL, Bunnell SC, Obstfeld AE, Jordan MS, Wu JN, Myung PS, Samelson LE, Koretzky GA. Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function. The Journal of Biological Chemistry. 279: 15481-90. PMID 14722089 DOI: 10.1074/jbc.M313339200  1
2003 Bunnell SC, Barr VA, Fuller CL, Samelson LE. High-resolution multicolor imaging of dynamic signaling complexes in T cells stimulated by planar substrates. Science's Stke : Signal Transduction Knowledge Environment. 2003: PL8. PMID 12684528 DOI: 10.1126/stke.2003.177.pl8  1
2002 Bunnell SC. Determining the destiny of NF-kappa B after TCR ligation: it's CARMA1. Molecular Interventions. 2: 356-60, 338. PMID 14993411 DOI: 10.1124/mi.2.6.356  1
2002 Bunnell SC, Hong DI, Kardon JR, Yamazaki T, McGlade CJ, Barr VA, Samelson LE. T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. The Journal of Cell Biology. 158: 1263-75. PMID 12356870 DOI: 10.1083/jcb.200203043  1
2001 Bunnell SC, Kapoor V, Trible RP, Zhang W, Samelson LE. Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. Immunity. 14: 315-29. PMID 11290340 DOI: 10.1016/S1074-7613(01)00112-1  1
2000 Shan X, Czar MJ, Bunnell SC, Liu P, Liu Y, Schwartzberg PL, Wange RL. Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Molecular and Cellular Biology. 20: 6945-57. PMID 10958690 DOI: 10.1128/MCB.20.18.6945-6957.2000  1
2000 Bunnell SC, Diehn M, Yaffe MB, Findell PR, Cantley LC, Berg LJ. Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade. The Journal of Biological Chemistry. 275: 2219-30. PMID 10636929 DOI: 10.1074/jbc.275.3.2219  1
1999 Samelson LE, Bunnell SC, Trible RP, Yamazaki T, Zhang W. Studies on the adapter molecule LAT. Cold Spring Harbor Symposia On Quantitative Biology. 64: 259-63. PMID 11232294 DOI: 10.1101/sqb.1999.64.259  1
1998 Bunnell SC, Berg LJ. The signal transduction of motion and antigen recognition: factors affecting T cell function and differentiation. Genetic Engineering. 20: 63-110. PMID 9666556  1
1998 Liu KQ, Bunnell SC, Gurniak CB, Berg LJ. T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells. The Journal of Experimental Medicine. 187: 1721-7. PMID 9584150 DOI: 10.1084/jem.187.10.1721  1
1997 Heyeck SD, Wilcox HM, Bunnell SC, Berg LJ. Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity. The Journal of Biological Chemistry. 272: 25401-8. PMID 9312162 DOI: 10.1074/jbc.272.40.25401  1
1997 Andreotti AH, Bunnell SC, Feng S, Berg LJ, Schreiber SL. Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature. 385: 93-7. PMID 8985255 DOI: 10.1038/385093a0  1
1996 Bunnell SC, Henry PA, Kolluri R, Kirchhausen T, Rickles RJ, Berg LJ. Identification of Itk/Tsk Src homology 3 domain ligands. The Journal of Biological Chemistry. 271: 25646-56. PMID 8810341 DOI: 10.1074/jbc.271.41.25646  1
1996 Bedard DL, Bunnell SC, Smullen LA. Stimulation of microbial para-dechlorination of polychlorinated biphenyls that have persisted in housatonic river sediment for decades Environmental Science and Technology. 30: 687-694. DOI: 10.1021/es950463i  1
1995 Raab M, Cai YC, Bunnell SC, Heyeck SD, Berg LJ, Rudd CE. p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation. Proceedings of the National Academy of Sciences of the United States of America. 92: 8891-5. PMID 7568038  1
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