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Jurgen Rohr - Publications

Affiliations: 
Pharmaceutical Sciences University of Kentucky, Lexington, KY 
Area:
Pharmacy, Biochemistry
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Year Citation  Score
2019 Bilobrov V, Sokolova V, Prylutska S, Panchuk R, Litsis O, Osetskyi V, Evstigneev M, Prylutskyy Y, Epple M, Ritter U, Rohr J. A Novel Nanoconjugate of Landomycin A with C60 Fullerene for Cancer Targeted Therapy: In Vitro Studies. Cellular and Molecular Bioengineering. 12: 41-51. PMID 31719898 DOI: 10.1007/S12195-018-0548-5  0.301
2019 Wheeler R, Yu X, Hou C, Mitra P, Chen JM, Herkules F, Ivanov DN, Tsodikov OV, Rohr J. Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis. Angewandte Chemie (International Ed. in English). PMID 31702856 DOI: 10.1002/Anie.201910241  0.36
2019 Savi DC, Noriler SA, Ponomareva LV, Thorson JS, Rohr J, Glienke C, Shaaban KA. Dihydroisocoumarins produced by Diaporthe cf. heveae LGMF1631 inhibiting citrus pathogens. Folia Microbiologica. PMID 31401763 DOI: 10.1007/S12223-019-00746-8  0.319
2019 Noriler SA, Savi DC, Ponomareva LV, Rohr J, Thorson JS, Rodrigues R, Glienke C, Shaaban KA. Vochysiamides A and B: Two new bioactive carboxamides produced by the new species Diaporthe vochysiae. Fitoterapia. 104273. PMID 31344395 DOI: 10.1016/J.Fitote.2019.104273  0.344
2019 Hou C, Rohr J, Parkin S, Tsodikov OV. How mithramycin stereochemistry dictates its structure and DNA binding function. Medchemcomm. 10: 735-741. PMID 31191864 DOI: 10.1039/C9Md00100J  0.3
2019 Hayden RC, Hou C, Mitra P, Mandal A, Rohr J, Thorson J, Tsodikov O, Leggas M. Abstract 2954: Mithramycin analogues disrupt ETS transcription factor DNA binding Cancer Research. 79: 2954-2954. DOI: 10.1158/1538-7445.Sabcs18-2954  0.301
2018 Savi DC, Shaaban KA, Gos FMW, Thorson JS, Glienke C, Rohr J. Secondary metabolites produced by Microbacterium sp. LGMB471 with antifungal activity against the phytopathogen Phyllosticta citricarpa. Folia Microbiologica. PMID 30565048 DOI: 10.1007/S12223-018-00668-X  0.324
2018 Cui Z, Wang XC, Liu X, Lemke A, Koppermann S, Ducho C, Rohr J, Thorson JS, Van Lanen SG. Self-Resistance During Muraymycin Biosynthesis: A Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order. Antimicrobial Agents and Chemotherapy. PMID 29735559 DOI: 10.1128/Aac.00193-18  0.398
2018 de Medeiros AG, Savi DC, Mitra P, Shaaban KA, Jha AK, Thorson JS, Rohr J, Glienke C. Bioprospecting of Diaporthe terebinthifolii LGMF907 for antimicrobial compounds. Folia Microbiologica. PMID 29497981 DOI: 10.1007/S12223-018-0587-2  0.345
2018 Savi DC, Shaaban KA, Gos FMWR, Ponomareva LV, Thorson JS, Glienke C, Rohr J. Phaeophleospora vochysiae Savi & Glienke sp. nov. Isolated from Vochysia divergens Found in the Pantanal, Brazil, Produces Bioactive Secondary Metabolites. Scientific Reports. 8: 3122. PMID 29449610 DOI: 10.1038/S41598-018-21400-2  0.336
2017 Krafczyk R, Macošek J, Jagtap PKA, Gast D, Wunder S, Mitra P, Jha AK, Rohr J, Hoffmann-Röder A, Jung K, Hennig J, Lassak J. Structural Basis for EarP-Mediated Arginine Glycosylation of Translation Elongation Factor EF-P. Mbio. 8. PMID 28951478 DOI: 10.1128/Mbio.01412-17  0.31
2017 Gos FMWR, Savi DC, Shaaban KA, Thorson JS, Aluizio R, Possiede YM, Rohr J, Glienke C. Antibacterial Activity of Endophytic Actinomycetes Isolated from the Medicinal Plant Vochysia divergens (Pantanal, Brazil). Frontiers in Microbiology. 8: 1642. PMID 28932210 DOI: 10.3389/Fmicb.2017.01642  0.308
2017 Salem SM, Weidenbach S, Rohr J. Two Cooperative Glycosyltransferases are Responsible for the Sugar Diversity of Saquayamycins Isolated from Streptomyces sp. KY 40-1. Acs Chemical Biology. PMID 28892347 DOI: 10.1021/Acschembio.7B00453  0.407
2017 Gao G, Liu X, Xu M, Wang Y, Zhang F, Xu L, Lv J, Long Q, Kang Q, Ou HY, Wang Y, Rohr J, Deng Z, Jiang M, Lin S, et al. Formation of an Angular Aromatic Polyketide from a Linear Anthrene Precursor via Oxidative Rearrangement. Cell Chemical Biology. PMID 28712746 DOI: 10.1016/J.Chembiol.2017.06.008  0.374
2017 Wang X, Elshahawi SI, Cai W, Zhang Y, Ponomareva LV, Chen X, Copley GC, Hower JC, Zhan CG, Parkin S, Rohr J, Van Lanen SG, Shaaban KA, Thorson JS. Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2. Journal of Natural Products. PMID 28358212 DOI: 10.1021/Acs.Jnatprod.7B00108  0.306
2017 Panchuk RR, Lehka LV, Terenzi A, Matselyukh BP, Rohr J, Jha AK, Downey T, Kril' IJ, Herbacek I, van Schonhoven S, Heffeter P, Stoika RS, Berger W. Rapid generation of hydrogen peroxide contributes to the complex cell death induction by the angucycline antibiotic landomycin E. Free Radical Biology & Medicine. PMID 28189848 DOI: 10.1016/J.Freeradbiomed.2017.02.024  0.604
2017 Wang G, Chen J, Zhu H, Rohr J. One-Pot Enzymatic Total Synthesis of Presteffimycinone, an Early Intermediate of the Anthracycline Antibiotic Steffimycin Biosynthesis. Organic Letters. PMID 28102686 DOI: 10.1021/Acs.Orglett.6B03708  0.33
2017 Goswami A, Liu X, Cai W, Wyche TP, Bugni TS, Meurillon M, Peyrottes S, Perigaud C, Nonaka K, Rohr J, Van Lanen SG. Evidence that Oxidative Dephosphorylation by the Non-heme Fe(II), α-Ketoglutarate:UMP Oxygenase Occurs by Stereospecific Hydroxylation. Febs Letters. PMID 28074470 DOI: 10.1002/1873-3468.12554  0.308
2016 Blundell RD, Williams SJ, Arras SD, Chitty JL, Blake KL, Ericsson DJ, Tibrewal N, Rohr J, Koh YQ, Kappler U, Robertson AA, Butler MS, Cooper MA, Kobe B, Fraser JA. Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans. Acs Infectious Diseases. 2: 651-663. PMID 27759389 DOI: 10.1021/Acsinfecdis.6B00121  0.36
2016 Pahari P, Saikia UP, Das TP, Damodaran C, Rohr J. Synthesis of Psoralidin derivatives and their anticancer activity: First synthesis of Lespeflorin I(1). Tetrahedron. 72: 3324-3334. PMID 27698514 DOI: 10.1016/J.Tet.2016.04.066  0.334
2016 Jackson D, Yu X, Wang G, Patel A, Barajas J, Sasaki E, Metsa-Ketala M, Liu HW, Rohr J, Tsai SS. Insights Into Complex Oxidation During BE-7585A Biosynthesis: Structural Determination and Analysis of the Polyketide Monooxygenase BexE. Acs Chemical Biology. PMID 26813028 DOI: 10.1021/Acschembio.5B00913  0.34
2015 Chen JM, Hou C, Wang G, Tsodikov OV, Rohr J. Structural insight into MtmC, a bifunctional ketoreductase-methyltransferase involved in the assembly of the mithramycin trisaccharide chain. Biochemistry. 54: 2481-9. PMID 25587924 DOI: 10.1021/Bi501462G  0.358
2015 Tam HK, Härle J, Gerhardt S, Rohr J, Wang G, Thorson JS, Bigot A, Lutterbeck M, Seiche W, Breit B, Bechthold A, Einsle O. Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2. Angewandte Chemie (International Ed. in English). 54: 2811-5. PMID 25581707 DOI: 10.1002/Anie.201409792  0.344
2015 Savi DC, Shaaban KA, Vargas N, Ponomareva LV, Possiede YM, Thorson JS, Glienke C, Rohr J. Microbispora sp. LGMB259 endophytic actinomycete isolated from Vochysia divergens (Pantanal, Brazil) producing β-carbolines and indoles with biological activity. Current Microbiology. 70: 345-54. PMID 25385358 DOI: 10.1007/S00284-014-0724-3  0.336
2014 Braña AF, Rodríguez M, Pahari P, Rohr J, García LA, Blanco G. Activation and silencing of secondary metabolites in Streptomyces albus and Streptomyces lividans after transformation with cosmids containing the thienamycin gene cluster from Streptomyces cattleya. Archives of Microbiology. 196: 345-55. PMID 24633227 DOI: 10.1007/S00203-014-0977-Z  0.372
2014 Singh S, Zhang J, Huber TD, Sunkara M, Hurley K, Goff RD, Wang G, Zhang W, Liu C, Rohr J, Van Lanen SG, Morris AJ, Thorson JS. Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues. Angewandte Chemie (International Ed. in English). 53: 3965-9. PMID 24616228 DOI: 10.1002/Anie.201308272  0.362
2013 Bosserman MA, Downey T, Noinaj N, Buchanan SK, Rohr J. Molecular insight into substrate recognition and catalysis of Baeyer-Villiger monooxygenase MtmOIV, the key frame-modifying enzyme in the biosynthesis of anticancer agent mithramycin. Acs Chemical Biology. 8: 2466-77. PMID 23992662 DOI: 10.1021/Cb400399B  0.665
2013 Garcia I, Vior NM, González-Sabín J, Braña AF, Rohr J, Moris F, Méndez C, Salas JA. Engineering the biosynthesis of the polyketide-nonribosomal peptide collismycin A for generation of analogs with neuroprotective activity. Chemistry & Biology. 20: 1022-32. PMID 23911584 DOI: 10.1016/J.Chembiol.2013.06.014  0.348
2013 Scott D, Chen JM, Bae Y, Rohr J. Semi-synthetic mithramycin SA derivatives with improved anticancer activity. Chemical Biology & Drug Design. 81: 615-24. PMID 23331575 DOI: 10.1111/Cbdd.12107  0.312
2013 Chen J, Wang G, Rohr J. The Biosynthetic Pathway to TDP-D-Fucofuranose, the Sugar Donor Substrate for the C-Glycosyltranferase Involved in Gilvocarcin V Biosynthesis Planta Medica. 79. DOI: 10.1055/S-0033-1348674  0.343
2013 Downey T, Bosserman M, Noinaj N, Buchanan S, Rohr J. Investigating and Re-Engineering Baeyer-Villiger Monooxygenase MtmOIV for Combinatorial Biosynthesis of Novel Aureolic Acid Anticancer Drug Analogues Planta Medica. 79. DOI: 10.1055/S-0033-1348553  0.6
2012 Barnard-Britson S, Chi X, Nonaka K, Spork AP, Tibrewal N, Goswami A, Pahari P, Ducho C, Rohr J, Van Lanen SG. Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase. Journal of the American Chemical Society. 134: 18514-7. PMID 23110675 DOI: 10.1021/Ja308185Q  0.387
2012 Tibrewal N, Pahari P, Wang G, Kharel MK, Morris C, Downey T, Hou Y, Bugni TS, Rohr J. Baeyer-Villiger C-C bond cleavage reaction in gilvocarcin and jadomycin biosynthesis. Journal of the American Chemical Society. 134: 18181-4. PMID 23102024 DOI: 10.1021/Ja3081154  0.653
2012 Shaaban KA, Shepherd MD, Ahmed TA, Nybo SE, Leggas M, Rohr J. Pyramidamycins A-D and 3-hydroxyquinoline-2-carboxamide; cytotoxic benzamides from Streptomyces sp. DGC1. The Journal of Antibiotics. 65: 615-22. PMID 23047245 DOI: 10.1038/Ja.2012.81  0.734
2012 Wang G, Pahari P, Kharel MK, Chen J, Zhu H, Van Lanen SG, Rohr J. Cooperation of two bifunctional enzymes in the biosynthesis and attachment of deoxysugars of the antitumor antibiotic mithramycin. Angewandte Chemie (International Ed. in English). 51: 10638-42. PMID 22997042 DOI: 10.1002/Anie.201205414  0.36
2012 Tibrewal N, Downey TE, Van Lanen SG, Ul Sharif E, O'Doherty GA, Rohr J. Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway. Journal of the American Chemical Society. 134: 12402-5. PMID 22800463 DOI: 10.1021/Ja305113D  0.633
2012 Shaaban KA, Ahmed TA, Leggas M, Rohr J. Saquayamycins G-K, cytotoxic angucyclines from Streptomyces sp. Including two analogues bearing the aminosugar rednose. Journal of Natural Products. 75: 1383-92. PMID 22758660 DOI: 10.1021/Np300316B  0.34
2012 Patrikainen P, Kallio P, Fan K, Klika KD, Shaaban KA, Mäntsälä P, Rohr J, Yang K, Niemi J, Metsä-Ketelä M. Tailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities. Chemistry & Biology. 19: 647-55. PMID 22633416 DOI: 10.1016/J.Chembiol.2012.04.010  0.358
2012 Núñez LE, Nybo SE, González-Sabín J, Pérez M, Menéndez N, Braña AF, Shaaban KA, He M, Morís F, Salas JA, Rohr J, Méndez C. A novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis. Journal of Medicinal Chemistry. 55: 5813-25. PMID 22578073 DOI: 10.1021/Jm300234T  0.74
2012 Kharel MK, Rohr J. Delineation of gilvocarcin, jadomycin, and landomycin pathways through combinatorial biosynthetic enzymology. Current Opinion in Chemical Biology. 16: 150-61. PMID 22465094 DOI: 10.1016/J.Cbpa.2012.03.007  0.379
2012 Kharel MK, Pahari P, Shaaban KA, Wang G, Morris C, Rohr J. Elucidation of post-PKS tailoring steps involved in landomycin biosynthesis. Organic & Biomolecular Chemistry. 10: 4256-65. PMID 22454092 DOI: 10.1039/C2Ob07171A  0.383
2012 Garcia I, Vior NM, Braña AF, González-Sabin J, Rohr J, Moris F, Méndez C, Salas JA. Elucidating the biosynthetic pathway for the polyketide-nonribosomal peptide collismycin A: mechanism for formation of the 2,2'-bipyridyl ring. Chemistry & Biology. 19: 399-413. PMID 22444595 DOI: 10.1016/J.Chembiol.2012.01.014  0.338
2012 Nybo SE, Shabaan KA, Kharel MK, Sutardjo H, Salas JA, Méndez C, Rohr J. Ketoolivosyl-tetracenomycin C: a new ketosugar bearing tetracenomycin reveals new insight into the substrate flexibility of glycosyltransferase ElmGT. Bioorganic & Medicinal Chemistry Letters. 22: 2247-50. PMID 22361136 DOI: 10.1016/J.Bmcl.2012.01.094  0.758
2012 Pahari P, Kharel MK, Shepherd MD, van Lanen SG, Rohr J. Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis. Angewandte Chemie (International Ed. in English). 51: 1216-20. PMID 22223167 DOI: 10.1002/Anie.201105882  0.415
2012 Kharel MK, Pahari P, Shepherd MD, Tibrewal N, Nybo SE, Shaaban KA, Rohr J. Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis. Natural Product Reports. 29: 264-325. PMID 22186970 DOI: 10.1039/C1Np00068C  0.739
2012 Tibrewal N, Downey T, Rohr J. Synergistic reductive methyltransferase GILM and its crucial role in gilvocarcin biosynthetic pathway Planta Medica. 78. DOI: 10.1055/S-0032-1320333  0.605
2012 Wang G, Pahari P, Kharel M, Van Lanen S, Rohr J. Two bifunctional enzymes, MTM GIV and MTM C, involved in the biosynthesis of deoxysugar moieties of the antitumor antibiotic mithramycin Planta Medica. 78. DOI: 10.1055/S-0032-1320284  0.354
2011 Wang G, Kharel MK, Pahari P, Rohr J. Investigating Mithramycin deoxysugar biosynthesis: enzymatic total synthesis of TDP-D-olivose. Chembiochem : a European Journal of Chemical Biology. 12: 2568-71. PMID 21960454 DOI: 10.1002/Cbic.201100540  0.34
2011 Sleiman SF, Langley BC, Basso M, Berlin J, Xia L, Payappilly JB, Kharel MK, Guo H, Marsh JL, Thompson LM, Mahishi L, Ahuja P, MacLellan WR, Geschwind DH, Coppola G, ... Rohr J, et al. Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6858-70. PMID 21543616 DOI: 10.1523/Jneurosci.0710-11.2011  0.311
2011 Kharel MK, Lian H, Rohr J. Characterization of the TDP-D-ravidosamine biosynthetic pathway: one-pot enzymatic synthesis of TDP-D-ravidosamine from thymidine-5-phosphate and glucose-1-phosphate. Organic & Biomolecular Chemistry. 9: 1799-808. PMID 21264378 DOI: 10.1039/C0Ob00854K  0.345
2011 Bosserman MA, Flórez AB, Shaaban KA, Braña AF, Salas JA, Méndez C, Rohr J. Characterization of the terminal activation step catalyzed by oxygenase CmmOIV of the chromomycin biosynthetic pathway from Streptomyces griseus. Biochemistry. 50: 1421-8. PMID 21244022 DOI: 10.1021/Bi1016205  0.364
2011 Yang Z, Chi X, Funabashi M, Baba S, Nonaka K, Pahari P, Unrine J, Jacobsen JM, Elliott GI, Rohr J, Van Lanen SG. Characterization of LipL as a non-heme, Fe(II)-dependent α-ketoglutarate:UMP dioxygenase that generates uridine-5'-aldehyde during A-90289 biosynthesis. The Journal of Biological Chemistry. 286: 7885-92. PMID 21216959 DOI: 10.1074/Jbc.M110.203562  0.302
2011 Shaaban KA, Srinivasan S, Kumar R, Damodaran C, Rohr J. Landomycins P-W, cytotoxic angucyclines from Streptomyces cyanogenus S-136. Journal of Natural Products. 74: 2-11. PMID 21188999 DOI: 10.1021/Np100469Y  0.341
2011 Shepherd MD, Liu T, Méndez C, Salas JA, Rohr J. Engineered biosynthesis of gilvocarcin analogues with altered deoxyhexopyranose moieties. Applied and Environmental Microbiology. 77: 435-41. PMID 21075894 DOI: 10.1128/Aem.01774-10  0.353
2011 Shaaban KA, Stamatkin C, Damodaran C, Rohr J. 11-Deoxylandomycinone and landomycins X-Z, new cytotoxic angucyclin(on)es from a Streptomyces cyanogenus K62 mutant strain. The Journal of Antibiotics. 64: 141-50. PMID 20978514 DOI: 10.1038/Ja.2010.121  0.317
2010 Kharel MK, Shepherd MD, Nybo SE, Smith ML, Bosserman MA, Rohr J. Isolation of Streptomyces species from soil. Current Protocols in Microbiology. Unit 10E.4. PMID 21053254 DOI: 10.1002/9780471729259.Mc10E04S19  0.709
2010 Nybo SE, Shepherd MD, Bosserman MA, Rohr J. Genetic manipulation of Streptomyces species. Current Protocols in Microbiology. Unit 10E.3. PMID 21053253 DOI: 10.1002/9780471729259.Mc10E03S19  0.716
2010 Shepherd MD, Kharel MK, Zhu LL, van Lanen SG, Rohr J. Delineating the earliest steps of gilvocarcin biosynthesis: role of GilP and GilQ in starter unit specificity. Organic & Biomolecular Chemistry. 8: 3851-6. PMID 20617244 DOI: 10.1039/C0Ob00036A  0.309
2010 Ostash B, Ostash I, Zhu L, Kharel MK, Luzhetskiǐ A, Bechthold A, Walker S, Rohr J, Fedorenko V. Properties of lanK-based regulatory circuit involved in landomycin biosynthesis in Streptomyces cyanogenus S136 Genetika. 46: 604-609. PMID 20583594 DOI: 10.1134/S1022795410050030  0.322
2010 Kharel MK, Pahari P, Lian H, Rohr J. Enzymatic total synthesis of rabelomycin, an angucycline group antibiotic. Organic Letters. 12: 2814-7. PMID 20486694 DOI: 10.1021/Ol1009009  0.356
2010 Kharel MK, Nybo SE, Shepherd MD, Rohr J. Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clusters. Chembiochem : a European Journal of Chemical Biology. 11: 523-32. PMID 20140934 DOI: 10.1002/Cbic.200900673  0.748
2010 Kharel MK, Pahari P, Lian H, Rohr J. Corrigendum: GilR, an Unusual Lactone-Forming Enzyme Involved in Gilvocarcin Biosynthesis Chembiochem. 11: 1161-1161. DOI: 10.1002/Cbic.201090040  0.324
2009 Kharel MK, Pahari P, Lian H, Rohr J. GilR, an unusual lactone-forming enzyme involved in gilvocarcin biosynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 1305-8. PMID 19388008 DOI: 10.1002/Cbic.200900130  0.331
2009 Beam MP, Bosserman MA, Noinaj N, Wehenkel M, Rohr J. Crystal structure of Baeyer-Villiger monooxygenase MtmOIV, the key enzyme of the mithramycin biosynthetic pathway . Biochemistry. 48: 4476-87. PMID 19364090 DOI: 10.1021/Bi8023509  0.743
2009 Pahari P, Rohr J. Total synthesis of psoralidin, an anticancer natural product. The Journal of Organic Chemistry. 74: 2750-4. PMID 19254011 DOI: 10.1021/Jo8025884  0.32
2009 Liu T, Kharel MK, Zhu L, Bright SA, Mattingly C, Adams VR, Rohr J. Inactivation of the ketoreductase gilU gene of the gilvocarcin biosynthetic gene cluster yields new analogues with partly improved biological activity. Chembiochem : a European Journal of Chemical Biology. 10: 278-86. PMID 19067453 DOI: 10.1002/Cbic.200800348  0.433
2009 Lombó F, Abdelfattah MS, Braña AF, Salas JA, Rohr J, Méndez C. Elucidation of oxygenation steps during oviedomycin biosynthesis and generation of derivatives with increased antitumor activity. Chembiochem : a European Journal of Chemical Biology. 10: 296-303. PMID 18988223 DOI: 10.1002/Cbic.200800425  0.358
2008 Pérez M, Baig I, Braña AF, Salas JA, Rohr J, Méndez C. Generation of new derivatives of the antitumor antibiotic mithramycin by altering the glycosylation pattern through combinatorial biosynthesis. Chembiochem : a European Journal of Chemical Biology. 9: 2295-304. PMID 18756551 DOI: 10.1002/Cbic.200800299  0.349
2008 Abdelfattah MS, Kharel MK, Hitron JA, Baig I, Rohr J. Moromycins A and B, isolation and structure elucidation of C-glycosylangucycline-type antibiotics from Streptomyces sp. KY002. Journal of Natural Products. 71: 1569-73. PMID 18666798 DOI: 10.1021/Np800281F  0.352
2008 Ramos A, Lombó F, Braña AF, Rohr J, Méndez C, Salas JA. Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster. Microbiology (Reading, England). 154: 781-8. PMID 18310024 DOI: 10.1099/Mic.0.2007/014035-0  0.364
2008 Olano C, Abdelfattah MS, Gullón S, Braña AF, Rohr J, Méndez C, Salas JA. Glycosylated derivatives of steffimycin: insights into the role of the sugar moieties for the biological activity. Chembiochem : a European Journal of Chemical Biology. 9: 624-33. PMID 18224649 DOI: 10.1002/Cbic.200700610  0.387
2008 Baig I, Perez M, Braña AF, Gomathinayagam R, Damodaran C, Salas JA, Méndez C, Rohr J. Mithramycin analogues generated by combinatorial biosynthesis show improved bioactivity. Journal of Natural Products. 71: 199-207. PMID 18197601 DOI: 10.1021/Np0705763  0.365
2007 Kharel MK, Zhu L, Liu T, Rohr J. Multi-oxygenase complexes of the gilvocarcin and jadomycin biosyntheses. Journal of the American Chemical Society. 129: 3780-1. PMID 17346045 DOI: 10.1021/Ja0680515  0.416
2007 Zhu L, Luzhetskyy A, Luzhetska M, Mattingly C, Adams V, Bechthold A, Rohr J. Generation of new landomycins with altered saccharide patterns through over-expression of the glycosyltransferase gene lanGT3 in the biosynthetic gene cluster of landomycin A in Streptomyces cyanogenus S-136. Chembiochem : a European Journal of Chemical Biology. 8: 83-8. PMID 17139690 DOI: 10.1002/Cbic.200600360  0.391
2006 Rohr J. Cryptophycin anticancer drugs revisited. Acs Chemical Biology. 1: 747-50. PMID 17240971 DOI: 10.1021/Cb6004678  0.324
2006 Baig I, Kharel M, Kobylyanskyy A, Zhu L, Rebets Y, Ostash B, Luzhetskyy A, Bechthold A, Fedorenko VA, Rohr J. On the acceptor substrate of C-glycosyltransferase UrdGT2: three prejadomycin C-Glycosides from an engineered mutant of Streptomyces globisporus 1912 DeltalndE(urdGT2). Angewandte Chemie (International Ed. in English). 45: 7842-6. PMID 17061307 DOI: 10.1002/Anie.200603176  0.333
2006 Pérez M, Lombó F, Baig I, Braña AF, Rohr J, Salas JA, Méndez C. Combinatorial biosynthesis of antitumor deoxysugar pathways in Streptomyces griseus: Reconstitution of "unnatural natural gene clusters" for the biosynthesis of four 2,6-D-dideoxyhexoses. Applied and Environmental Microbiology. 72: 6644-52. PMID 17021216 DOI: 10.1128/Aem.01266-06  0.34
2006 Garrido LM, Lombó F, Baig I, Nur-E-Alam M, Furlan RL, Borda CC, Braña A, Méndez C, Salas JA, Rohr J, Padilla G. Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes. Applied Microbiology and Biotechnology. 73: 122-31. PMID 16810496 DOI: 10.1007/S00253-006-0453-Z  0.37
2006 Liu T, Kharel MK, Fischer C, McCormick A, Rohr J. Inactivation of gilGT, encoding a C-glycosyltransferase, and gilOIII, encoding a P450 enzyme, allows the details of the late biosynthetic pathway to gilvocarcin V to be delineated. Chembiochem : a European Journal of Chemical Biology. 7: 1070-7. PMID 16795121 DOI: 10.1002/Cbic.200600031  0.373
2006 Gullón S, Olano C, Abdelfattah MS, Braña AF, Rohr J, Méndez C, Salas JA. Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin. Applied and Environmental Microbiology. 72: 4172-83. PMID 16751529 DOI: 10.1128/Aem.00734-06  0.343
2006 Albertini V, Jain A, Vignati S, Napoli S, Rinaldi A, Kwee I, Nur-e-Alam M, Bergant J, Bertoni F, Carbone GM, Rohr J, Catapano CV. Novel GC-rich DNA-binding compound produced by a genetically engineered mutant of the mithramycin producer Streptomyces argillaceus exhibits improved transcriptional repressor activity: implications for cancer therapy. Nucleic Acids Research. 34: 1721-34. PMID 16571899 DOI: 10.1093/Nar/Gkl063  0.319
2005 Gibson M, Nur-e-alam M, Lipata F, Oliveira MA, Rohr J. Characterization of kinetics and products of the Baeyer-Villiger oxygenase MtmOIV, the key enzyme of the biosynthetic pathway toward the natural product anticancer drug mithramycin from Streptomyces argillaceus. Journal of the American Chemical Society. 127: 17594-5. PMID 16351075 DOI: 10.1021/Ja055750T  0.394
2005 Salas AP, Zhu L, Sánchez C, Braña AF, Rohr J, Méndez C, Salas JA. Deciphering the late steps in the biosynthesis of the anti-tumour indolocarbazole staurosporine: sugar donor substrate flexibility of the StaG glycosyltransferase. Molecular Microbiology. 58: 17-27. PMID 16164546 DOI: 10.1111/J.1365-2958.2005.04777.X  0.343
2005 Chen YH, Wang CC, Greenwell L, Rix U, Hoffmeister D, Vining LC, Rohr J, Yang KQ. Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase Journal of Biological Chemistry. 280: 22508-22514. PMID 15817470 DOI: 10.1074/Jbc.M414229200  0.361
2005 Luzhetskyy A, Zhu L, Gibson M, Fedoryshyn M, Dürr C, Hofmann C, Hoffmeister D, Ostash B, Mattingly C, Adams V, Fedorenko V, Rohr J, Bechthold A. Generation of novel landomycins M and O through targeted gene disruption. Chembiochem : a European Journal of Chemical Biology. 6: 675-8. PMID 15812784 DOI: 10.1002/Cbic.200400316  0.331
2005 Rix U, Wang C, Chen Y, Lipata FM, Rix LLR, Greenwell LM, Vining LC, Yang K, Rohr J. The oxidative ring cleavage in jadomycin biosynthesis: A multistep oxygenation cascade in a biosynthetic black box Chembiochem. 6: 838-845. PMID 15776503 DOI: 10.1002/Cbic.200400395  0.389
2005 Pérez M, Lombó F, Zhu L, Gibson M, Braña AF, Rohr J, Salas JA, Méndez C. Combining sugar biosynthesis genes for the generation of L- and D-amicetose and formation of two novel antitumor tetracenomycins. Chemical Communications (Cambridge, England). 1604-6. PMID 15770274 DOI: 10.1039/B417815G  0.33
2005 Zhu L, Ostash B, Rix U, Nur-E-Alam M, Mayers A, Luzhetskyy A, Mendez C, Salas JA, Bechthold A, Fedorenko V, Rohr J. Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycinone. The Journal of Organic Chemistry. 70: 631-8. PMID 15651811 DOI: 10.1021/Jo0483623  0.384
2005 Sánchez C, Zhu L, Braña AF, Salas AP, Rohr J, Méndez C, Salas JA. Combinatorial biosynthesis of antitumor indolocarbazole compounds. Proceedings of the National Academy of Sciences of the United States of America. 102: 461-6. PMID 15625109 DOI: 10.1073/Pnas.0407809102  0.377
2004 Lombó F, Gibson M, Greenwell L, Braña AF, Rohr J, Salas JA, Méndez C. Engineering biosynthetic pathways for deoxysugars: branched-chain sugar pathways and derivatives from the antitumor tetracenomycin. Chemistry & Biology. 11: 1709-18. PMID 15610855 DOI: 10.1016/J.Chembiol.2004.10.007  0.356
2004 Luzhetskyy A, Liu T, Fedoryshyn M, Ostash B, Fedorenko V, Rohr J, Bechthold A. Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis. Chembiochem : a European Journal of Chemical Biology. 5: 1567-70. PMID 15515090 DOI: 10.1002/Cbic.200400123  0.328
2004 Liu T, Fischer C, Beninga C, Rohr J. Oxidative rearrangement processes in the biosynthesis of gilvocarcin V. Journal of the American Chemical Society. 126: 12262-3. PMID 15453748 DOI: 10.1021/Ja0467521  0.371
2004 Menéndez N, Nur-E-Alam M, Braña AF, Rohr J, Salas JA, Méndez C. Tailoring modification of deoxysugars during biosynthesis of the antitumour drug chromomycin A by Streptomyces griseus ssp. griseus. Molecular Microbiology. 53: 903-15. PMID 15255901 DOI: 10.1111/J.1365-2958.2004.04166.X  0.361
2004 Pérez-Zúñiga FJ, Seco EM, Cuesta T, Degenhardt F, Rohr J, Vallín C, Iznaga Y, Pérez ME, González L, Malpartida F. CE-108, a new macrolide tetraene antibiotic. The Journal of Antibiotics. 57: 197-204. PMID 15152805 DOI: 10.7164/Antibiotics.57.197  0.323
2004 Ostash B, Rix U, Rix LL, Liu T, Lombo F, Luzhetskyy A, Gromyko O, Wang C, Braña AF, Méndez C, Salas JA, Fedorenko V, Rohr J. Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus. Chemistry & Biology. 11: 547-55. PMID 15123249 DOI: 10.1016/J.Chembiol.2004.03.011  0.377
2004 Menéndez N, Nur-e-Alam M, Braña AF, Rohr J, Salas JA, Méndez C. Biosynthesis of the antitumor chromomycin A3 in Streptomyces griseus: analysis of the gene cluster and rational design of novel chromomycin analogs. Chemistry & Biology. 11: 21-32. PMID 15112992 DOI: 10.1016/J.Chembiol.2003.12.011  0.318
2003 Remsing LL, Bahadori HR, Carbone GM, McGuffie EM, Catapano CV, Rohr J. Inhibition of c-src transcription by mithramycin: structure-activity relationships of biosynthetically produced mithramycin analogues using the c-src promoter as target. Biochemistry. 42: 8313-24. PMID 12846580 DOI: 10.1021/Bi034091Z  0.332
2003 Fischer C, Lipata F, Rohr J. The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins. Journal of the American Chemical Society. 125: 7818-9. PMID 12822997 DOI: 10.1021/Ja034781Q  0.389
2003 Remsing LL, González AM, Nur-e-Alam M, Fernández-Lozano MJ, Braña AF, Rix U, Oliveira MA, Méndez C, Salas JA, Rohr J. Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis. Journal of the American Chemical Society. 125: 5745-53. PMID 12733914 DOI: 10.1021/Ja034162H  0.378
2003 Hoffmeister D, Dräger G, Ichinose K, Rohr J, Bechthold A. The C-Glycosyltransferase UrdGT2 is unselective toward d- and l-configured nucleotide-bound rhodinoses. Journal of the American Chemical Society. 125: 4678-9. PMID 12696864 DOI: 10.1021/Ja029645K  0.351
2003 Rix U, Remsing LL, Hoffmeister D, Bechthold A, Rohr J. Urdamycin L: a novel metabolic shunt product that provides evidence for the role of the urdM gene in the urdamycin A biosynthetic pathway of Streptomyces fradiae TU 2717. Chembiochem : a European Journal of Chemical Biology. 4: 109-11. PMID 12512084 DOI: 10.1002/Cbic.200390002  0.321
2002 Fischer C, Rodríguez L, Patallo EP, Lipata F, Braña AF, Méndez C, Salas JA, Rohr J. Digitoxosyltetracenomycin C and glucosyltetracenomycin C, two novel elloramycin analogues obtained by exploring the sugar donor substrate specificity of glycosyltransferase ElmGT. Journal of Natural Products. 65: 1685-9. PMID 12444703 DOI: 10.1021/Np020112Z  0.355
2002 Méndez C, Künzel E, Lipata F, Lombó F, Cotham W, Walla M, Bearden DW, Braña AF, Salas JA, Rohr J. Oviedomycin, an unusual angucyclinone encoded by genes of the oleandomycin-producer Streptomyces antibioticus ATCC11891. Journal of Natural Products. 65: 779-82. PMID 12027768 DOI: 10.1021/Np010555N  0.345
2002 Trefzer A, Blanco G, Remsing L, Künzel E, Rix U, Lipata F, Braña AF, Méndez C, Rohr J, Bechthold A, Salas JA. Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways. Journal of the American Chemical Society. 124: 6056-62. PMID 12022840 DOI: 10.1021/Ja017385L  0.39
2002 Sánchez C, Butovich IA, Braña AF, Rohr J, Méndez C, Salas JA. The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives. Chemistry & Biology. 9: 519-31. PMID 11983340 DOI: 10.1016/S1074-5521(02)00126-6  0.344
2002 Macky TA, Oelkers C, Rix U, Heredia ML, Künzel E, Wimberly M, Rohrer B, Crosson CE, Rohr J. Synthesis, pharmacokinetics, efficacy, and rat retinal toxicity of a novel mitomycin C-triamcinolone acetonide conjugate. Journal of Medicinal Chemistry. 45: 1122-7. PMID 11855992 DOI: 10.1021/Jm010511B  0.31
2002 Remsing LL, Garcia-Bernardo J, Gonzalez A, Künzel E, Rix U, Braña AF, Bearden DW, Méndez C, Salas JA, Rohr J. Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway. Journal of the American Chemical Society. 124: 1606-14. PMID 11853433 DOI: 10.1021/Ja0105156  0.432
2002 Trefzer A, Fischer C, Stockert S, Westrich L, Künzel E, Girreser U, Rohr J, Bechthold A. Elucidation of the function of two glycosyltransferase genes (lanGT1 and lanGT4) involved in landomycin biosynthesis and generation of new oligosaccharide antibiotics. Chemistry & Biology. 8: 1239-52. PMID 11755402 DOI: 10.1016/S1074-5521(01)00091-6  0.383
2001 Patallo EP, Blanco G, Fischer C, Brana AF, Rohr J, Mendez C, Salas JA. Deoxysugar methylation during biosynthesis of the antitumor polyketide elloramycin by Streptomyces olivaceus. Characterization of three methyltransferase genes. The Journal of Biological Chemistry. 276: 18765-74. PMID 11376004 DOI: 10.1074/Jbc.M101225200  0.373
2001 Blanco G, Patallo EP, Braña AF, Trefzer A, Bechthold A, Rohr J, Méndez C, Salas JA. Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin. Chemistry & Biology. 8: 253-63. PMID 11306350 DOI: 10.1016/S1074-5521(01)00010-2  0.392
2001 González A, Remsing LL, Lombó F, Fernández MJ, Prado L, Braña AF, Künzel E, Rohr J, Méndez C, Salas JA. The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties. Molecular & General Genetics : Mgg. 264: 827-35. PMID 11254130 DOI: 10.1007/S004380000372  0.366
2000 Hoffmeister D, Ichinose K, Domann S, Faust B, Trefzer A, Dräger G, Kirschning A, Fischer C, Künzel E, Bearden DW, Rohr J, Bechthold A. The NDP-sugar co-substrate concentration and the enzyme expression level influence the substrate specificity of glycosyltransferases: Cloning and characterization of deoxysugar biosynthetic genes of the urdamycin biosynthetic gene cluster Chemistry and Biology. 7: 821-831. PMID 11094336 DOI: 10.1016/S1074-5521(00)00029-6  0.367
2000 Trefzer A, Hoffmeister D, Künzel E, Stockert S, Weitnauer G, Westrich L, Rix U, Fuchser J, Bindseil KU, Rohr J, Bechthold A. Function of glycosyltransferase genes involved in urdamycin A biosynthesis. Chemistry & Biology. 7: 133-42. PMID 10662691 DOI: 10.1016/S1074-5521(00)00079-X  0.327
2000 Blanco G, Fernández E, Fernández MJ, Braña AF, Weissbach U, Künzel E, Rohr J, Méndez C, Salas JA. Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus. Molecular & General Genetics : Mgg. 262: 991-1000. PMID 10660060 DOI: 10.1007/Pl00008667  0.366
2000 Faust B, Hoffmeister D, Weitnauer G, Westrich L, Haag S, Schneider P, Decker H, Künzel E, Rohr J, Bechthold A. Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tü2717. Microbiology (Reading, England). 146: 147-54. PMID 10658661 DOI: 10.1099/00221287-146-1-147  0.392
2000 Lozano MJ, Remsing LL, Quirós LM, Braña AF, Fernández E, Sánchez C, Méndez C, Rohr J, Salas JA. Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus. The Journal of Biological Chemistry. 275: 3065-74. PMID 10652287 DOI: 10.1074/Jbc.275.5.3065  0.349
1999 Prado L, Lombó F, Braña AF, Méndez C, Rohr J, Salas JA. Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus. Molecular & General Genetics : Mgg. 261: 216-25. PMID 10102355 DOI: 10.1007/S004380050960  0.345
1999 Prado L, Fernández E, Weissbach U, Blanco G, Quirós LM, Braña AF, Méndez C, Rohr J, Salas JA. Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin. Chemistry & Biology. 6: 19-30. PMID 9889148 DOI: 10.1016/S1074-5521(99)80017-9  0.301
1999 Künzel E, Faust B, Oelkers C, Weissbach U, Bearden DW, Weitnauer G, Westrich L, Bechthold A, Rohr J. Inactivation of the urdGT2 gene, which encodes a glycosyltransferase responsible for the C-glycosyltransfer of activated D-olivose, leads to formation of the novel urdamycins I, J, and K Journal of the American Chemical Society. 121: 11058-11062. DOI: 10.1021/Ja9915347  0.384
1999 Rohr J, Méndez C, Salas JA. The biosynthesis of aureolic acid group antibiotics Bioorganic Chemistry. 27: 41-54. DOI: 10.1006/Bioo.1998.1110  0.332
1998 Fernández E, Weissbach U, Sánchez Reillo C, Braña AF, Méndez C, Rohr J, Salas JA. Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin. Journal of Bacteriology. 180: 4929-37. PMID 9733697 DOI: 10.1128/Jb.180.18.4929-4937.1998  0.389
1997 Rohr J, Wohlert S, Oelkers C, Kirschning A, Ries M. Biosynthetic short activation of the 2,3,6-trideoxysugarl-rhodinose Chemical Communications. 973-974. DOI: 10.1039/A702125I  0.305
1997 Krohn K, Rohr J. Angucyclines : Total Syntheses, New Structures, And Biosynthetic Studies Of An Emerging New Class Of Antibiotics Topics in Current Chemistry. 188: 127-195. DOI: 10.1007/Bfb0119236  0.331
1997 Kirschning A, Bechthold AFW, Rohr J. Chemical and biochemical aspects of deoxysugars and deoxysugar oligosaccharides Topics in Current Chemistry. 188: 1-84. DOI: 10.1007/Bfb0119234  0.355
1997 Künzel E, Wohlert SE, Beninga C, Haag S, Decker H, Hutchinson CR, Blanco G, Mendez C, Salas JA, Rohr J. Tetracenomycin M, a novel genetically engineered tetracenomycin resulting from a combination of mithramycin and tetracenomycin biosynthetic genes Chemistry - a European Journal. 3: 1675-1678. DOI: 10.1002/Chem.19970031017  0.386
1997 Rohr J. Biosynthesis of Taxol Angewandte Chemie (International Edition in English). 36: 2190-2195. DOI: 10.1002/Anie.199721901  0.328
1996 Blum S, Groth I, Rohr J, Fielder HP. Biosynthetic capacities of actinomycetes. 5. Dioxolides, novel secondary metabolites from Streptomyces tendae. Journal of Basic Microbiology. 36: 19-25. PMID 8819841 DOI: 10.1002/Jobm.3620360105  0.309
1995 Decker H, Rohr J, Motamedi H, Zähner H, Hutchinson CR. Identification of Streptomyces olivaceus Tü 2353 genes involved in the production of the polyketide elloramycin. Gene. 166: 121-6. PMID 8529875 DOI: 10.1016/0378-1119(95)00573-7  0.33
1995 Rohr J. Combinatorial Biosynthesis–An Approach in the Near Future? Angewandte Chemie International Edition in English. 34: 881-885. DOI: 10.1002/Anie.199508811  0.34
1990 Henkel T, Rohr J, Beale JM, Schwenen L. Landomycins, new angucycline antibiotics from Streptomyces SP. I. Structural studies on landomycins A~D Journal of Antibiotics. 43: 492-503. PMID 2358402 DOI: 10.7164/Antibiotics.43.492  0.351
1990 Rohr J, Zeeck A. Structure-activity relationships of elloramycin and tetracenomycin C Journal of Antibiotics. 43: 1169-1178. PMID 2211379 DOI: 10.7164/Antibiotics.43.1169  0.35
1989 Henkel T, Ciesiolka T, Rohr J, Zeeck A. Urdamycins, new angucycline antibiotics from streptomyces fradiae. V. Derivatives of urdamycin A Journal of Antibiotics. 42: 299-311. PMID 2925521 DOI: 10.7164/Antibiotics.42.299  0.329
1989 Rohr J. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. VI. Structure elucidation and biosynthetic investigations on urdamycin H Journal of Antibiotics. 42: 1482-1488. PMID 2808135 DOI: 10.7164/Antibiotics.42.1482  0.383
1989 Rohr J, Beale JM, Floss HG. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. IV. Biosynthetic studies of urdamycins A-D. The Journal of Antibiotics. 42: 1151-7. PMID 2753820 DOI: 10.7164/Antibiotics.42.1151  0.335
1988 Rohr J, Zeeck A, Floss HG. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. III. The structures of urdamycins C and D. The Journal of Antibiotics. 41: 126-9. PMID 3346183 DOI: 10.7164/Antibiotics.41.126  0.329
1988 Rohr J, Eick S, Zeeck A, Reuschenbach P, Zähner H, Fiedler H. Metabolic products of microorganisms. 249. Tetracenomycins B3 and D3, key intermediates of the elloramycin and tetracenomycin C biosynthesis. The Journal of Antibiotics. 41: 1066-1073. PMID 3170342 DOI: 10.7164/Antibiotics.41.1066  0.348
1987 Rohr J, Zeeck A. Metabolic products of microorganisms. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. II. Structural studies of urdamycins B to F Journal of Antibiotics. 40: 459-467. PMID 3583915 DOI: 10.7164/Antibiotics.40.459  0.344
1986 Drautz H, Zahner H, Rohr J, Zeeck A. Metabolic products of microorganisms. 234. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. I. Isolation, characterization and biological properties Journal of Antibiotics. 39: 1657-1669. PMID 3818439 DOI: 10.7164/Antibiotics.39.1657  0.377
1985 Drautz H, Reuschenbach P, Zahner H, Rohr J, Zeeck A. Metabolic products of microorganisms. 225 Elloramycin, a new anthracycline-like antibiotic from Streptomyces olivaceus. Isolation, characterization, structure and biological properties Journal of Antibiotics. 38: 1291-1301. PMID 3840789 DOI: 10.7164/Antibiotics.38.1291  0.384
Low-probability matches (unlikely to be authored by this person)
2006 Menéndez N, Nur-e-Alam M, Fischer C, Braña AF, Salas JA, Rohr J, Méndez C. Deoxysugar transfer during chromomycin A3 biosynthesis in Streptomyces griseus subsp. griseus: new derivatives with antitumor activity. Applied and Environmental Microbiology. 72: 167-77. PMID 16391039 DOI: 10.1128/Aem.72.1.167-177.2006  0.299
2004 Rix U, Zheng J, Remsing Rix LL, Greenwell L, Yang K, Rohr J. The dynamic structure of jadomycin B and the amino acid incorporation step of its biosynthesis. Journal of the American Chemical Society. 126: 4496-7. PMID 15070349 DOI: 10.1021/Ja031724O  0.299
1994 Rohr J. Antibiotics and Antiviral Compounds. Chemical Synthesis and Modification. Herausgegeben vonK. Krohn, H. A. Kirst undH. Maag. VCH Verlagsgesellschaft, Weinheim/VCH Publishers, New York, 1993. 482 S., geb. 128.00 DM, 53.00 £. - ISBN 3-527-29040-0/1-56081-745-3 Angewandte Chemie. 106: 1065-1066. DOI: 10.1002/Ange.19941060936  0.297
2015 Lassak J, Keilhauer EC, Fürst M, Wuichet K, Gödeke J, Starosta AL, Chen JM, Søgaard-Andersen L, Rohr J, Wilson DN, Häussler S, Mann M, Jung K. Arginine-rhamnosylation as new strategy to activate translation elongation factor P. Nature Chemical Biology. 11: 266-70. PMID 25686373 DOI: 10.1038/Nchembio.1751  0.297
2000 Lombó F, Künzel E, Prado L, Braña AF, Bindseil KU, Frevert J, Bearden D, Méndez C, Salas JA, Rohr J. The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin. Angewandte Chemie (International Ed. in English). 39: 796-799. PMID 10760873 DOI: 10.1002/(Sici)1521-3773(20000218)39:4<796::Aid-Anie796>3.0.Co;2-N  0.297
2019 Savi DC, Shaaban KA, Mitra P, Ponomareva LV, Thorson JS, Glienke C, Rohr J. Secondary metabolites produced by the citrus phytopathogen Phyllosticta citricarpa. The Journal of Antibiotics. PMID 30792517 DOI: 10.1038/S41429-019-0154-3  0.294
1998 Rohr J, Weißbach U, Beninga C, Künzel E, Siems K, Bindseil KU, Lombó F, Prado L, Braña AF, Méndez C, Salas JA. The Structures Of Premithramycinone And Demethylpremithramycinone, Plausible Early Intermediates Of The Aureolic Acid Group Antibiotic Mithramycin Chemical Communications. 437-438. DOI: 10.1039/A707446H  0.292
2011 Sleiman SF, Berlin J, Basso M, Karuppagounder SS, Rohr J, Ratan RR. Histone Deacetylase Inhibitors and Mithramycin A Impact a Similar Neuroprotective Pathway at a Crossroad between Cancer and Neurodegeneration. Pharmaceuticals (Basel, Switzerland). 4: 1183-1195. PMID 22582024 DOI: 10.3390/Ph4081183  0.292
1993 Thiericke R, Rohr J. Biological variation of microbial metabolites by precursor-directed biosynthesis Natural Product Reports. 10: 265-289. PMID 8351079 DOI: 10.1039/Np9931000265  0.291
2012 Wang G, Pahari P, Kharel MK, Chen J, Zhu H, Van Lanen SG, Rohr J. Zusammenwirken zweier difunktionaler Enzyme bei Aufbau und Verknüpfung von Desoxyzuckern des Antitumor-Antibiotikums Mithramycin Angewandte Chemie. 124: 10790-10794. DOI: 10.1002/Ange.201205414  0.29
1986 Zeeck A, Rohr J, Sheldrick GM, Jones PG, Paulus EF. Structure of a New Antibiotic and Cytotoxic Indicator Substance, Urdamycin A. Cheminform. 17. DOI: 10.1002/Chin.198634343  0.289
2005 Wang C, Gibson M, Rohr J, Oliveira MA. Crystallization and X-ray diffraction properties of Baeyer-Villiger monooxygenase MtmOIV from the mithramycin biosynthetic pathway in Streptomyces argillaceus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 1023-6. PMID 16511225 DOI: 10.1107/S1744309105033221  0.288
2018 Leggas M, Eckenrode J, Mitra P, Jha A, Salem S, Mandal A, Thorson J, Rohr J. Abstract B043: Mithramycin-SA analogues with reduced toxicity for the treatment of ETS transcription factor-driven tumors Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B043  0.288
2015 Tam HK, Härle J, Gerhardt S, Rohr J, Wang G, Thorson JS, Bigot A, Lutterbeck M, Seiche W, Breit B, Bechthold A, Einsle O. Strukturelle Charakterisierung von O- und C-glycosylierenden Varianten der Landomycin-Glycosyltransferase LanGT2 Angewandte Chemie. 127: 2853-2857. DOI: 10.1002/Ange.201409792  0.286
2010 Previdi S, Malek A, Albertini V, Riva C, Capella C, Broggini M, Carbone GM, Rohr J, Catapano CV. Inhibition of Sp1-dependent transcription and antitumor activity of the new aureolic acid analogues mithramycin SDK and SK in human ovarian cancer xenografts. Gynecologic Oncology. 118: 182-8. PMID 20452660 DOI: 10.1016/J.Ygyno.2010.03.020  0.285
2019 Gober R, Wheeler R, Rohr J. Post-PKS enzyme complexes Medchemcomm. 10: 1855-1866. DOI: 10.1039/C9Md00066F  0.285
1992 Egert E, Noltemeyer M, Siebers J, Rohr J, Zeeck A. The structure of tetracenomycin C Journal of Antibiotics. 45: 1190-1192. PMID 1517166 DOI: 10.7164/Antibiotics.45.1190  0.284
2015 Weidenbach S, Hou C, Chen JM, Tsodikov OV, Rohr J. Dimerization and DNA recognition rules of mithramycin and its analogues. Journal of Inorganic Biochemistry. 156: 40-47. PMID 26760230 DOI: 10.1016/J.Jinorgbio.2015.12.011  0.284
1986 Fiedler HP, Rohr J, Zeeck A. Elloramycins B, C, D, E, and F: Minor congeners of the elloramycin producer Streptomyces olivaceus Journal of Antibiotics. 39: 856-859. PMID 3755429 DOI: 10.7164/Antibiotics.39.856  0.28
1991 Schönewolf M, Grabley S, Hütter K, Machinek R, Wink J, Zeeck A, Rohr J. Secondary metabolites by chemical screening, 10. Glycerinopyrin, a novel metabolite from Streptomyces violaceus Liebigs Annalen Der Chemie. 1991: 77-80. DOI: 10.1002/Jlac.199119910114  0.279
2015 Eckenrode J, Horn J, Chen J, Rohr J, Leggas M. Abstract 2628: Mithramycin analogs with reduced toxicity for EWS-FLI1 targeting Cancer Research. 75: 2628-2628. DOI: 10.1158/1538-7445.Am2015-2628  0.276
1997 Meurer G, Gerlitz M, Wendt-Pienkowski E, Vining LC, Rohr J, Hutchinson CR. Iterative type II polyketide synthases, cyclases and ketoreductases exhibit context-dependent behavior in the biosynthesis of linear and angular decapolyketides Chemistry and Biology. 4: 433-443. PMID 9224566 DOI: 10.1016/S1074-5521(97)90195-2  0.274
2000 Rohr J. A new role for polyketides Angewandte Chemie - International Edition. 39: 2847-2849. DOI: 10.1002/1521-3773(20000818)39:16<2847::Aid-Anie2847>3.0.Co;2-0  0.274
2018 Mitra P, Eckenrode JM, Mandal A, Jha AK, Salem SM, Leggas M, Rohr J. Development of Mithramycin Analogues with Increased Selectivity towards ETS Transcription Factor Expressing Cancers. Journal of Medicinal Chemistry. PMID 30114371 DOI: 10.1021/Acs.Jmedchem.8B01107  0.273
2009 Zhao W, Zhu L, Srinivasan S, Damodaran C, Rohr J. Identification of urushiols as the major active principle of the Siddha herbal medicine Semecarpus Lehyam: Anti-tumor agents for the treatment of breast cancer. Pharmaceutical Biology. 47: 886-893. PMID 20617110 DOI: 10.1080/13880200902942410  0.273
2006 Baig I, Kharel M, Kobylyanskyy A, Zhu L, Rebets Y, Ostash B, Luzhetskyy A, Bechthold A, Fedorenko VA, Rohr J. Über das Acceptorsubstrat der C-Glycosyltransferase UrdGT2: drei Prejadomycin-C-glycoside aus einer konstruierten Mutante vonStreptomyces globisporus 1912 ΔlndE(urdGT2) Angewandte Chemie. 118: 8006-8010. DOI: 10.1002/Ange.200603176  0.272
2013 Shamaladevi N, Lyn DA, Shaaban KA, Zhang L, Villate S, Rohr J, Lokeshwar BL. Ericifolin: a novel antitumor compound from allspice that silences androgen receptor in prostate cancer. Carcinogenesis. 34: 1822-32. PMID 23568956 DOI: 10.1093/Carcin/Bgt123  0.271
2010 Sowmyalakshmi S, Kumar R, Pahari P, Rohr J, Damodaran C. Abstract 4387: Reactive oxygen species-mediated cell death by psoralidin in prostate cancer cells Cancer Research. 70: 4387-4387. DOI: 10.1158/1538-7445.Am10-4387  0.27
1999 Walker M, Pohl E, Herbst-Irmer R, Gerlitz M, Rohr J, Sheldrick GM. Absolute configurations of Emycin D, E and F; mimicry of centrosymmetric space groups by mixtures of chiral stereoisomers Acta Crystallographica Section B-Structural Science. 55: 607-616. PMID 10927402 DOI: 10.1107/S0108768199003948  0.269
1995 Decker H, Haag S, Udvarnoki G, Rohr J. Neue, gentechnisch hergestellte Tetracenomycine Angewandte Chemie. 107: 1214-1217. DOI: 10.1002/Ange.19951071019  0.266
1994 Bockholt H, Beale JM, Rohr J. Biosynthesestudien an Pyridazomycin Angewandte Chemie. 106: 1733-1735. DOI: 10.1002/Ange.19941061542  0.266
2016 Hou C, Weidenbach S, Cano KE, Wang Z, Mitra P, Ivanov DN, Rohr J, Tsodikov OV. Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Research. PMID 27587584 DOI: 10.1093/Nar/Gkw761  0.266
2011 Noinaj N, Bosserman MA, Schickli MA, Piszczek G, Kharel MK, Pahari P, Buchanan SK, Rohr J. The crystal structure and mechanism of an unusual oxidoreductase, GilR, involved in gilvocarcin V biosynthesis. The Journal of Biological Chemistry. 286: 23533-43. PMID 21561854 DOI: 10.1074/jbc.M111.247833  0.265
2011 Scott D, Rohr J, Bae Y. Nanoparticulate formulations of mithramycin analogs for enhanced cytotoxicity. International Journal of Nanomedicine. 6: 2757-67. PMID 22114504 DOI: 10.2147/Ijn.S25427  0.263
2009 Kumar R, Srinivasan S, Koduru S, Pahari P, Rohr J, Kyprianou N, Damodaran C. Psoralidin, an herbal molecule, inhibits phosphatidylinositol 3-kinase-mediated Akt signaling in androgen-independent prostate cancer cells. Cancer Prevention Research (Philadelphia, Pa.). 2: 234-43. PMID 19223576 DOI: 10.1158/1940-6207.Capr-08-0129  0.261
1995 Udvarnoki G, Wagner C, Machinek R, Rohr J. Biosynthetic Origin of the Oxygen Atoms of Tetracenomycin C Angewandte Chemie International Edition in English. 34: 565-567. DOI: 10.1002/Anie.199505651  0.26
2010 Koduru S, Rohr J, Damodaran C. Abstract 2491: Biphasic effect of psoralidin on cell cycle regulatory markers in hormone refractory prostate cancer Cancer Research. 70: 2491-2491. DOI: 10.1158/1538-7445.Am10-2491  0.26
1995 Udvarnoki G, Wagner C, Machinek R, Rohr J. Biosynthetische Herkunft der Sauerstoffatome von Tetracenomycin C Angewandte Chemie. 107: 643-645. DOI: 10.1002/Ange.19951070524  0.258
2004 Furlan RL, Watt SJ, Garrido LM, Amarante-Mendes GP, Nur-e-alam M, Rohr J, Braña A, Mendez C, Salas JA, Sheil MM, Beck JL, Padilla G. DNA-binding properties of cosmomycin D, an anthracycline with two trisaccharide chains. The Journal of Antibiotics. 57: 647-54. PMID 15638325 DOI: 10.7164/Antibiotics.57.647  0.257
1994 Rohr J. Book Review: Antibiotics and Antiviral Compounds. Chemical Synthesis and Modification. Edited by K. Krohn, H. A. Kirst and H. Maag Angewandte Chemie International Edition in English. 33: 1119-1120. DOI: 10.1002/Anie.199411192  0.256
2014 Savi D, Shaaban K, Thorson J, Glienke C, Rohr J. 1-vinyl-β-carboline-3-carboxylate isolated from endophytic Microbispora sp. LGMB259, with antibacterial and antifungal activies Planta Medica. 80. DOI: 10.1055/S-0034-1382395  0.256
1990 Rohr J. A novel type of ring contraction as non-enzymatic step in the later stages of the biosynthesis of urdamycin H Angewandte Chemie - International Edition in English. 29: 1051-1053. DOI: 10.1002/Anie.199010511  0.255
2005 Nur-e-Alam M, Méndez C, Salas JA, Rohr J. Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII. Chembiochem : a European Journal of Chemical Biology. 6: 632-6. PMID 15712316 DOI: 10.1002/Cbic.200400309  0.254
1994 Bockholt H, Beale JM, Rohr J. Biosynthetic investigations on pyridazomycin Angewandte Chemie - International Edition in English. 33: 1647-1651. DOI: 10.1002/Anie.199416481  0.252
2010 Kumar R, Srinivasan S, Pahari P, Rohr J, Damodaran C. Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer. Molecular Cancer Therapeutics. 9: 2488-96. PMID 20736346 DOI: 10.1158/1535-7163.Mct-10-0180  0.252
1991 Schonewolf M, Rohr J. Biogenesis of the carbon skeleton of glycerinopyrin: A new biosynthetic pathway for pyrroles Angewandte Chemie - International Edition in English. 30: 183-185. DOI: 10.1002/Anie.199101831  0.25
2010 Bosserman MA, Shepherd MD, Kharel MK, Rohr J. Laboratory maintenance of Streptomyces argillaceus and Streptomyces griseus. Current Protocols in Microbiology. Unit 10E.2. PMID 21053252 DOI: 10.1002/9780471729259.Mc10E02S19  0.248
2010 Damodaran C, Kumar R, Rohr J. Abstract 4140: Inhibition of mTOR signaling by psoralidin in breast cancer Cancer Research. 70: 4140-4140. DOI: 10.1158/1538-7445.Am10-4140  0.247
2015 Lassak J, Keilhauer EC, Fürst M, Wuichet K, Gödeke J, Starosta AL, Chen JM, Søgaard-Andersen L, Rohr J, Wilson DN, Häussler S, Mann M, Jung K. Corrigendum: Arginine-rhamnosylation as new strategy to activate translation elongation factor P. Nature Chemical Biology. 11: 299. PMID 25785429 DOI: 10.1038/Nchembio0415-299D  0.244
2004 Ranga RS, Girija R, Nur-e-Alam M, Sathishkumar S, Akbarsha MA, Thirugnanam S, Rohr J, Ahmed MM, Chendil D. Rasagenthi lehyam (RL) a novel complementary and alternative medicine for prostate cancer. Cancer Chemotherapy and Pharmacology. 54: 7-15. PMID 15042313 DOI: 10.1007/S00280-004-0770-9  0.242
1995 Gerlitz M, Udvarnoki G, Rohr J. Biosyntheses of novel emycins from the mutant strain Streptomyces cellulosae ssp. griseoincarnatus 1114-2 Angewandte Chemie (International Edition in English). 34: 1617-1621. DOI: 10.1002/Anie.199516171  0.242
1995 Rohr J. Shikimic Acid. Metabolism and Metabolites. VonE. Haslam. Wiley, Chichester, 1993. 387 S., geb. 75.00 £. – ISBN 0-471-93999-4 Angewandte Chemie. 107: 653-653. DOI: 10.1002/Ange.19951070532  0.241
2015 Matselyukh B, Mohammadipanah F, Laatsch H, Rohr J, Efremenkova O, Khilya V. N-methylphenylalanyl-dehydrobutyrine diketopiperazine, an A-factor mimic that restores antibiotic biosynthesis and morphogenesis in Streptomyces globisporus 1912-B2 and Streptomyces griseus 1439. The Journal of Antibiotics. 68: 9-14. PMID 25005816 DOI: 10.1038/Ja.2014.86  0.241
2019 Eckenrode JM, Mitra P, Rohr J, Leggas M. Bioanalytical method for quantitative determination of mithramycin analogues in mouse plasma by HPLC-QTOF. Biomedical Chromatography : Bmc. e4544. PMID 30927450 DOI: 10.1002/Bmc.4544  0.235
2016 Panchuk RR, Lehka LV, Rohr J, Berger W, Stoika RS. Mitochondria do not play a major role in landomycin E-induced ROS burst and circumvention of multiple drug resistance in HL-60 leukemia cells Biopolymers & Cell. 32: 190-202. DOI: 10.7124/Bc.000920  0.235
2009 Koduru S, Sowmyalakshmi S, Kumar R, Gomathinayagam R, Rohr J, Damodaran C. Identification of a potent herbal molecule for the treatment of breast cancer. Bmc Cancer. 9: 41. PMID 19183448 DOI: 10.1186/1471-2407-9-41  0.234
2016 Weidenbach S, Hou C, Chen JM, Tsodikov OV, Rohr J. Towards understanding the mechanism of action of mithramycin and its analogues: dimerization and DNA binding studies. Planta Medica. 81: S1-S381. PMID 27975447 DOI: 10.1055/S-0036-1596246  0.234
2010 Shepherd MD, Kharel MK, Bosserman MA, Rohr J. Laboratory maintenance of Streptomyces species. Current Protocols in Microbiology. Unit 10E.1. PMID 20812215 DOI: 10.1002/9780471729259.Mc10E01S18  0.234
2020 Hayden R, Mandal A, Liu Y, Hou C, Thorson J, Rohr J, Tsodikov O, Leggas M. Mithramycin analogues with unique mechanism of action in Ewing sarcoma The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04062  0.232
2010 Kumar R, Koduru S, Srinivasan S, Rohr J, Damodaran C. Abstract 4043: Targeting microRNA for the prevention and treatment of prostate cancer Cancer Research. 70: 4043-4043. DOI: 10.1158/1538-7445.Am10-4043  0.225
1995 Rohr J. Book Review: Shikimic Acid. By E. Haslam Angewandte Chemie International Edition in English. 34: 361-361. DOI: 10.1002/Anie.199503611  0.215
1990 Rohr J. A novel type of non-enzymatic reaction during the late steps in the biosynthesis of the angucycline antibiotics urdamycins C and D Journal of the Chemical Society, Chemical Communications. 113-114. DOI: 10.1039/C39900000113  0.213
1992 Rohr J, Thiericke R. Angucycline group antibiotics Natural Product Reports. 9: 103-137. PMID 1620493 DOI: 10.1039/Np9920900103  0.211
1997 Rohr J. Biosynthese von Taxol Angewandte Chemie. 109: 2284-2289. DOI: 10.1002/Ange.19971092008  0.206
2000 Lombó F, Künzel E, Prado L, Braña AF, Bindseil KU, Frevert J, Bearden D, Méndez C, Salas JA, Rohr J. Die antitumorwirksame Hybrid-Verbindung Premithramycinon H verweist indirekt auf ein tricyclisches Intermediat der Biosynthese des Aureolsäure-Antibiotikums Mithramycin Angewandte Chemie. 112: 808-811. DOI: 10.1002/(Sici)1521-3757(20000218)112:4<808::Aid-Ange808>3.0.Co;2-3  0.206
1995 Decker H, Haag S, Udvarnoki G, Rohr J. Novel genetically engineered tetracenomycins Angewandte Chemie (International Edition in English). 34: 1107-1110. DOI: 10.1002/Anie.199511071  0.206
2014 Chen JM, Shepherd MD, Horn J, Leggas M, Rohr J. Enzymatic methylation and structure-activity-relationship studies on polycarcin V, a gilvocarcin-type antitumor agent. Chembiochem : a European Journal of Chemical Biology. 15: 2729-35. PMID 25366963 DOI: 10.1002/Cbic.201402426  0.204
2005 Zheng JT, Rix U, Zhao L, Mattingly C, Adams V, Chen Q, Rohr J, Yang KQ. Cytotoxic activities of new jadomycin derivatives. The Journal of Antibiotics. 58: 405-8. PMID 16156517 DOI: 10.1038/Ja.2005.51  0.203
2014 Chen J, Hou C, Tsodikov O, Rohr J. Structural investigations of two bifunctional co-dependent enzymes, MtmGIV and MtmC, involved in the biosynthesis of mithramycin Planta Medica. 80. DOI: 10.1055/s-0034-1382745  0.201
1991 Schönewolf M, Rohr J. Biogenese des Kohlenstoffgerüsts von Glycerinopyrin: Ein neuartiger Biosyntheseweg für Pyrrole Angewandte Chemie. 103: 211-213. DOI: 10.1002/Ange.19911030228  0.199
2000 Rohr J. Eine neue Rolle für Polyketide Angewandte Chemie. 112: 2967-2969. DOI: 10.1002/1521-3757(20000818)112:16<2967::Aid-Ange2967>3.0.Co;2-H  0.196
1989 Rohr J. Biosynthetic formation of the S-methyl group of the angucycline antibiotic urdamycin E Journal of the Chemical Society, Chemical Communications. 492-493. DOI: 10.1039/C39890000492  0.195
1991 Rohr J. Grundlagen und Praxis der Biotechnologie. VonH. Diekmann undH. Metz. Gustav Fischer Verlag, Stuttgart 1991. 276 S., kartoniert DM 64.00. - ISBN 3-437-20462-9 Angewandte Chemie. 103: 1214-1215. DOI: 10.1002/Ange.19911030951  0.193
1990 Rohr J. Eine neuartige Ringkontraktion als nicht-enzymatischer Schritt der späten Urdamycin-H-Biosynthese Angewandte Chemie. 102: 1091-1092. DOI: 10.1002/Ange.19901020928  0.188
2021 Zhang Y, Cheema MT, Ponomareva LV, Ye Q, Liu T, Sajid I, Rohr J, She QB, Voss SR, Thorson JS, Shaaban KA. Himalaquinones A-G, Angucyclinone-Derived Metabolites Produced by the Himalayan Isolate sp. PU-MM59. Journal of Natural Products. PMID 34170698 DOI: 10.1021/acs.jnatprod.1c00192  0.188
2006 Abdelfattah MS, Rohr J. Premithramycinon G, ein frühes Shuntprodukt des Mithramycin-Biosyntheseweges, akkumuliert nach Inaktivierung der Oxygenase MtmOII Angewandte Chemie. 118: 5813-5818. DOI: 10.1002/Ange.200600511  0.187
2009 Cain J, Black EP, Rohr J. An audience response system strategy to improve student motivation, attention, and feedback. American Journal of Pharmaceutical Education. 73: 21. PMID 19513159 DOI: 10.5688/Aj730221  0.187
1995 Gerlitz M, Udvarnoki G, Rohr J. Biosynthese neuartiger Emycine aus dem Mutanten-StammStreptomyces cellulosae ssp.griseoincarnatus 1114-2 Angewandte Chemie. 107: 1757-1761. DOI: 10.1002/Ange.19951071525  0.186
1993 Rohr J, Schoenewolf M, Udvarnoki G, Eckardt K, Schumann G, Wagner C, Beale JM, Sorey SD. Investigations on the biosynthesis of the angucycline group antibiotics aquayamycin and the urdamycins A and B. Results from the structural analysis of novel blocked mutant products The Journal of Organic Chemistry. 58: 2547-2551. DOI: 10.1021/jo00061a032  0.179
1994 Weber S, Zolke C, Rohr J, Beale JM. Investigations of the biosynthesis and structural revision of landomycin A Journal of Organic Chemistry. 59: 4211-4214.  0.176
1995 Rohr J. Kombinatorische Biosynthese – eine Zukunftsstrategie? Angewandte Chemie. 107: 963-967. DOI: 10.1002/Ange.19951070806  0.174
2021 Iantas J, Savi DC, Schibelbein RDS, Noriler SA, Assad BM, Dilarri G, Ferreira H, Rohr J, Thorson JS, Shaaban KA, Glienke C. Endophytes of Brazilian Medicinal Plants With Activity Against Phytopathogens. Frontiers in Microbiology. 12: 714750. PMID 34539608 DOI: 10.3389/fmicb.2021.714750  0.17
1992 Rohr J. Comparison of multicyclic polyketides by folding analysis: A novel approach to recognize biosynthetic and/or evolutionary interrelationships of the natural products or intermediates and its exemplification on hepta-, octa-, and decaketides Journal of Organic Chemistry. 57: 5217-5223. DOI: 10.1021/jo00045a040  0.168
2008 Malek A, Núñez L, Menéndez N, Morís F, Carbone G, Rohr J, Méndez C, Salas J, Catapano C. 182 POSTER In vitro and in vivo antitumor activity of novel aureolic acid analogues generated by metabolic engineering of the biosynthetic pathways in Streptomyces argillaceus and treptomyces griseus subsp. griseus European Journal of Cancer Supplements. 6: 58. DOI: 10.1016/S1359-6349(08)72114-1  0.168
1999 Wohlert SE, Künzel E, Machinek R, Méndez C, Salas JA, Rohr J. The structure of mithramycin reinvestigated. Journal of Natural Products. 62: 119-21. PMID 9917296 DOI: 10.1021/np980355k  0.162
2020 Liu Y, Eckenrode JM, Zhang Y, Zhang J, Hayden RC, Kyomuhangi A, Ponomareva LV, Cui Z, Rohr J, Tsodikov OV, Van Lanen SG, Shaaban KA, Leggas M, Thorson JS. Mithramycin 2'-Oximes with Improved Selectivity, Pharmacokinetics, and Ewing Sarcoma Antitumor Efficacy. Journal of Medicinal Chemistry. PMID 33191745 DOI: 10.1021/acs.jmedchem.0c01526  0.158
1998 Wohlert SE, Blanco G, Lombó F, Fernández E, Braña AF, Reich S, Udvarnoki G, Méndez C, Decker H, Frevert J, Salas JA, Rohr J. Novel hybrid tetracenomycins through combinatorial biosynthesis using a glycosyltransferase encoded by the elm genes in cosmid 16F4 and which shows a broad sugar substrate specificity Journal of the American Chemical Society. 120: 10596-10601. DOI: 10.1021/Ja981687E  0.156
2023 Iantas J, Savi DC, Ponomareva L, Thorson JS, Rohr J, Glienke C, Shaaban KA. Paecilins Q and R: Antifungal chromanones produced by the endophytic fungus Pseudofusicoccum stromaticum CMRP4328. Planta Medica. PMID 36977488 DOI: 10.1055/a-2063-5481  0.156
2004 Albertini V, Vignati S, Rinaldi A, Bertoni F, Rohr J, Carbone G, Catapano C. 546 A novel aureolic acid antibiotic analogue has potent anti-proliferative activity and induces multiple changes in gene expression in ovarian cancer cells European Journal of Cancer Supplements. 2: 166. DOI: 10.1016/S1359-6349(04)80554-8  0.154
1992 Udvarnoki G, Henkel T, Machinek R, Rohr J. Biosynthetic origin of the oxygen atoms of aquayamycin: Aspects for the biosynthesis of the urdamycin family and for aquayamycin-containing angucycline antibiotics in general Journal of Organic Chemistry. 57: 1274-1276. DOI: 10.1021/jo00030a041  0.153
2010 KROHN K, ROHR J. ChemInform Abstract: Angucyclines: Total Syntheses, New Structures, and Biosynthetic Studies of an Emerging New Class of Antibiotics Cheminform. 28: no-no. DOI: 10.1002/chin.199737344  0.153
2021 Terenzi A, La Franca M, van Schoonhoven S, Panchuk R, Martínez Á, Heffeter P, Gober R, Pirker C, Vician P, Kowol CR, Stoika R, Salassa L, Rohr J, Berger W. Landomycins as glutathione-depleting agents and natural fluorescent probes for cellular Michael adduct-dependent quinone metabolism. Communications Chemistry. 4: 162. PMID 36697631 DOI: 10.1038/s42004-021-00600-4  0.149
2014 Yu X, Metsä-Ketelä M, Tsai S, Liu H, Rohr J. Roles of the key enzymes involved in the angucycline core formation in the BE-7585A biosynthesis Planta Medica. 80. DOI: 10.1055/S-0034-1382628  0.147
2002 Rix U, Fischer C, Remsing LL, Rohr J. Modification of post-PKS tailoring steps through combinatorial biosynthesis. Natural Product Reports. 19: 542-80. PMID 12430723 DOI: 10.1039/B103920M  0.142
2015 Tam HK, Härle J, Gerhardt S, Rohr J, Wang G, Thorson JS, Bigot A, Lutterbeck M, Seiche W, Breit B, Bechthold A, Einsle O. Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2 Angewandte Chemie - International Edition. 54: 2811-2815. DOI: 10.1002/anie.201409792  0.138
1998 Matselyukh BP, Lukyanchuk VV, Polishchuk LV, Matselyukh AB, Rohr J. Isolation and restriction analysis of two plasmids from Streptomyces globisporus 1912 Biopolymers and Cell. 14: 238-241. DOI: 10.7124/bc.0004D3  0.126
1968 Weinreich J, Busch D, Gottstein U, Schaefer J, Rohr J. Über zwei neue Fälle von hereditärer nichtsphärocytärer hämolytischer Anämie bei Glucose-6-Phosphat-Dehydrogenase-Defekt in einer norddeutschen Familie - I. Mitteilung Klinische Wochenschrift. 46: 146-149. PMID 5667020 DOI: 10.1007/BF01727373  0.124
2010 ROHR J, ET AL. EA. ChemInform Abstract: The Structures of Premithramycinone and Demethylpremithramycinone, Plausible Early Intermediates of the Aureolic Acid Group Antibiotic Mithramycin. Cheminform. 29: no-no. DOI: 10.1002/chin.199821215  0.122
2008 Rohr JA. Foreword Ethics and Integrity of Governance: Perspectives Across Frontiers. DOI: 10.4337/9781848441378.00007  0.12
2006 Abdelfattah MS, Rohr J. Premithramycinone G, an early shunt product of the mithramycin biosynthetic pathway accumulated upon inactivation of oxygenase MtmOII. Angewandte Chemie (International Ed. in English). 45: 5685-9. PMID 16856198 DOI: 10.1002/anie.200600511  0.118
2020 Hou C, Mandal A, Rohr J, Tsodikov OV. Allosteric Interference in Oncogenic FLI1 and ERG Transactions by Mithramycins. Structure (London, England : 1993). PMID 33275876 DOI: 10.1016/j.str.2020.11.012  0.117
2010 SCHOENEWOLF M, ROHR J. ChemInform Abstract: Biogenesis of the Carbon Framework in Glycerinopyrin: A New Type Biosynthesis Pathway of Pyrrols. Cheminform. 22: no-no. DOI: 10.1002/chin.199117280  0.114
2010 SCHOENEWOLF M, GRABLEY S, HUETTER K, MACHINEK R, WINK J, ZEECK A, ROHR J. ChemInform Abstract: Secondary Metabolites by Chemical Screening. Part 10. Glycerinopyrin, a Novel Metabolite from Streptomyces violaceus. Cheminform. 22: no-no. DOI: 10.1002/chin.199116281  0.112
2006 Previdi S, Albertini V, Nur-e-Alam M, Kwee I, Broggini M, Carbone G, Rohr J, Catapano C. 308 POSTER Antitumor activity of the new aureolic acid derivatives mithramycin SDK and SK in human ovarian cancer xenografts European Journal of Cancer Supplements. 4: 97. DOI: 10.1016/S1359-6349(06)70313-5  0.106
2010 KIRSCHNING A, BECHTHOLD AF, ROHR J. ChemInform Abstract: Chemical and Biochemical Aspects of Deoxysugars and Deoxysugar Oligosaccharides Cheminform. 28: no-no. DOI: 10.1002/chin.199738328  0.099
2021 Schweer D, McCorkle JR, Rohr J, Tsodikov OV, Ueland F, Kolesar J. Mithramycin and Analogs for Overcoming Cisplatin Resistance in Ovarian Cancer. Biomedicines. 9. PMID 33445667 DOI: 10.3390/biomedicines9010070  0.097
2010 ROHR J, WOHLERT S, OELKERS C, KIRSCHNING A, RIES M. ChemInform Abstract: Biosynthetic Short Activation of the 2,3,6-Trideoxysugar L-Rhodinose. Cheminform. 28: no-no. DOI: 10.1002/chin.199742246  0.097
1979 de Moerloose P, Jeannet M, Martins-da-Silva B, Werner-Favre C, Rohr J, Gauthier G. Increased frequency of HLA--DRw2 and DRw3 in multiple sclerosis. Tissue Antigens. 13: 357-60. PMID 91212 DOI: 10.1111/J.1399-0039.1979.TB00808.X  0.092
2010 BOCKHOLT H, BEALE JM, ROHR J. ChemInform Abstract: Biosynthetic Investigations on Pyridazomycin (I). Cheminform. 26: no-no. DOI: 10.1002/chin.199502234  0.089
2005 Sowmyalakshmi S, Nur-E-Alam M, Akbarsha MA, Thirugnanam S, Rohr J, Chendil D. Investigation on Semecarpus Lehyam--a Siddha medicine for breast cancer. Planta. 220: 910-8. PMID 15517350 DOI: 10.1007/s00425-004-1405-4  0.086
2022 Bhosale SS, Mandal A, Hou C, McCorkle JR, Schweer D, Hill KS, Kolesar JM, Tsodikov OV, Rohr J, Subramanian V. Mithplatins: Mithramycin SA-Pt(II) Complex Conjugates for the Treatment of Platinum Resistant Ovarian Cancers. Chemmedchem. PMID 36342449 DOI: 10.1002/cmdc.202200368  0.084
2012 Rohr JR, Martin LB. Reduce, reuse, recycle scientific reviews. Trends in Ecology & Evolution. 27: 192-3. PMID 22341497 DOI: 10.1016/J.Tree.2012.01.012  0.081
2005 Rohr JR, Crumrine PW. Effects of an herbicide and an insecticide on pond community structure and processes Ecological Applications. 15: 1135-1147.  0.08
1994 Bockholt H, Udvarnoki G, Rohr J, Mocek U, Beale JM, Floss HG. Biosynthetic studies on the xanthone antibiotics lysolipins X and I The Journal of Organic Chemistry. 59: 2064-2069. DOI: 10.1021/jo00087a021  0.074
1986 Roth G, Rohr J, Magistris MR. Motor neuropathy with proximal multifocal persistent conduction block, fasciculations and myokymia: Evolution to tetraplegia European Neurology. 25: 416-423. PMID 3024989 DOI: 10.1159/000116045  0.071
2016 Jennings DE, Krupa JJ, Rohr JR. Foraging modality and plasticity in foraging traits determine the strength of competitive interactions among carnivorous plants, spiders, and toads. The Journal of Animal Ecology. PMID 27061175 DOI: 10.1111/1365-2656.12526  0.069
2011 Jennings DE, Rohr JR. A review of the conservation threats to carnivorous plants Biological Conservation. 144: 1356-1363. DOI: 10.1016/J.Biocon.2011.03.013  0.068
2001 Rohr J. ChemInform Abstract: Oxygenases and Glycosyltransferases in Combinatorial Biosynthetic Approaches Cheminform. 32: no-no. DOI: 10.1002/chin.200105292  0.066
2005 Rohr JR, Palmer BD. Aquatic herbicide exposure increases salamander desiccation risk eight months later in a terrestrial environment. Environmental Toxicology and Chemistry / Setac. 24: 1253-8. PMID 16111008 DOI: 10.1897/04-448R.1  0.065
2013 Rohr JR, Palmer BD. Climate change, multiple stressors, and the decline of ectotherms. Conservation Biology : the Journal of the Society For Conservation Biology. 27: 741-51. PMID 23773091 DOI: 10.1111/Cobi.12086  0.062
1951 Rohr JH, Kraus I, Freeman S. Effect of Alkalis on Conjugation of Sulfonamides with Glucuronic and Acetic Acid Proceedings of the Society For Experimental Biology and Medicine. 77: 60-63. PMID 14844395 DOI: 10.3181/00379727-77-18678  0.062
2003 Rohr JR, Madison DM. Dryness increases predation risk in efts: support for an amphibian decline hypothesis. Oecologia. 135: 657-64. PMID 16228260 DOI: 10.1007/S00442-003-1206-7  0.061
2006 Rohr J, Speckmann C, Henneke P, Ehl S. Genetic susceptibility to invasive pneumococcal infections Padiatrische Praxis. 69: 301-312.  0.061
2009 Schulze I, Rohr J, Speckmann C. Congenital disorders of immune regulation Monatsschrift Fur Kinderheilkunde. 157: 878-885. DOI: 10.1007/s00112-009-1988-8  0.059
1991 Lundell CM, Rohr JJ. Interface friction: An owner's perspective Geotextiles and Geomembranes. 10: 499-505.  0.058
2006 Nachtigall I, Deja M, Halle E, Kastrup M, Weber-Carstens S, Krieg H, Puhlmann B, Eggers V, Heymann A, Rohr J, Viviano E, von Dossow V, MacGuill M, Sander M, Göbel U, et al. [Implementation of standard operating procedures for the initial empirical antimicrobial therapy for adults--a new computer program at the University Hospital Charité]. AnäSthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : Ains. 41: 626-35. PMID 17063411 DOI: 10.1055/s-2006-955857  0.057
1947 ROHR JH, FREEMAN S. The comparative effect of various alkalis and urea upon the blood concentration, excretion, and conjugation of sulfonamides with glucuronic and acetic acid Proceedings [of the] Annual Meeting. Central Society For Clinical Research (U.S.). 20: 69. PMID 20341013  0.057
2014 McMahon TA, Rohr JR. Trypan blue dye is an effective and inexpensive way to determine the viability of Batrachochytrium dendrobatidis zoospores. Ecohealth. 11: 164-7. PMID 24519684 DOI: 10.1007/S10393-014-0908-0  0.056
1965 ROHR JH, SCHEUREN JP. DRUGS AND ALLERGY. ALTHOUGH A USEFUL DRUG IS A GREAT FRIEND TO MAN, IT ALSO MAY BE HIS DEADLIEST ENEMY The Journal of the Kansas Medical Society. 66. PMID 14270256  0.054
2008 Speckmann C, Rohr J, Ehl S. Genetic disorders of immune regulation Primary Immunodeficiency Diseases: Definition, Diagnosis, and Management. 167-194. DOI: 10.1007/978-3-540-78936-9_5  0.054
2004 Latz MI, Nauen JC, Rohr J. Bioluminescence response of four species of dinoflagellates to fully developed pipe flow Journal of Plankton Research. 26: 1529-1546. DOI: 10.1093/Plankt/Fbh141  0.053
2004 Rohr JJ, Fish FE. Strouhal numbers and optimization of swimming by odontocete cetaceans Journal of Experimental Biology. 207: 1633-1642. PMID 15073196 DOI: 10.1242/Jeb.00948  0.053
2006 Rohr JR, Kerby JL, Sih A. Community ecology as a framework for predicting contaminant effects. Trends in Ecology & Evolution. 21: 606-13. PMID 16843566 DOI: 10.1016/J.Tree.2006.07.002  0.053
2011 Rohr J. Conformity and self-assertion the indigenous peoples of Russia's far North Osteuropa. 61: 387-406.  0.053
2009 Clements WH, Rohr JR. Community responses to contaminants: using basic ecological principles to predict ecotoxicological effects. Environmental Toxicology and Chemistry / Setac. 28: 1789-800. PMID 19358627 DOI: 10.1897/09-140.1  0.052
2001 Rohr JR, Madison DM. A chemically mediated trade-off between predation risk and mate search in newts Animal Behaviour. 62: 863-869. DOI: 10.1006/Anbe.2001.1816  0.052
2010 Rohr JR, Mccoy KA. Preserving environmental health and scientific credibility: A practical guide to reducing conflicts of interest Conservation Letters. 3: 143-150. DOI: 10.1111/J.1755-263X.2010.00114.X  0.051
2003 Fish FE, Peacock JE, Rohr JJ. Stabilization mechanism in swimming odontocete cetaceans by phased movements Marine Mammal Science. 19: 515-528.  0.051
2012 Rohr JR, Martin LB. Type I error is unlikely to hinder review recycling: A reply to Montesinos Trends in Ecology and Evolution. 27: 312-313. DOI: 10.1016/J.Tree.2012.03.005  0.051
1985 Gauthier G, Rohr J, Wildi E, Megret M. The spontaneous dissecting hematoma of the internal carotid artery: A review of 205 published - including 10 new - cases Schweizer Archiv Fur Neurologie Und Psychiatrie. 136: 53-74. PMID 2409590  0.049
2010 Rohr JR, McCoy KA. A qualitative meta-analysis reveals consistent effects of atrazine on freshwater fish and amphibians. Environmental Health Perspectives. 118: 20-32. PMID 20056568 DOI: 10.1289/Ehp.0901164  0.049
2004 Prasad A, Rohr JF. Control of nitrogen oxides emissions from ammonia combustion Proceedings of the Air and Waste Management Association's Annual Conference and Exhibition, Awma.  0.049
2002 Rohr JJ, Fish FE, Gilpatrick JW. Maximum swim speeds of captive and free-ranging delphinids: Critical analysis of extraordinary performance Marine Mammal Science. 18: 1-19.  0.049
2012 Visootsak J, Charen K, Rohr J, Allen E, Sherman S. Diagnosis of fragile X syndrome: A qualitative study of African American families Journal of Genetic Counseling. 21: 845-853. PMID 22134579 DOI: 10.1007/s10897-011-9454-x  0.048
1986 Rohr J, Hillion C, Gauthier G. Ultrasonic examinations and indication to angiography. A comparative study Schweizer Archiv Fur Neurologie Und Psychiatrie. 137: 45-62. PMID 2422748  0.047
2013 Latz MI, Rohr J. Bathyphotometer bioluminescence potential measurements: A framework for characterizing flow agitators and predicting flow-stimulated bioluminescence intensity Continental Shelf Research. 61: 71-84. DOI: 10.1016/J.Csr.2013.04.033  0.046
2013 Li Y, Cohen JM, Rohr JR. Review and synthesis of the effects of climate change on amphibians Integrative Zoology. 8: 145-161. PMID 23731811 DOI: 10.1111/1749-4877.12001  0.046
1978 Berbatis CG, Rohr JB. Guidelines for topical antimicrobials Australian Journal of Pharmacy. 59: 671-673.  0.045
1992 Rohr JA. French constitutionalism and the administrative state: A Comparative Textual Study Administration &Amp; Society. 24: 224-258. DOI: 10.1177/009539979202400207  0.044
1981 Gauthier G, Rohr J. Prevention of cerebrovascular attacks Therapeutische Umschau. 38: 717-721. PMID 7281058  0.043
2013 Sears B, Snyder P, Rohr J. No effects of two anesthetic agents on circulating leukocyte counts or resistance to Trematode infections in larval amphibians Journal of Herpetology. 47: 498-501. DOI: 10.1670/12-144  0.043
2010 Rohr J, Hertweck C. Type II PKS Comprehensive Natural Products Ii: Chemistry and Biology. 1: 227-303.  0.042
2005 Latz M, Rohr J. GI owing with the flow Optics and Photonics News. 16: 40-45. DOI: 10.1364/Opn.16.10.000040  0.042
1995 Latz MI, Rohr J, Hoyt J. A Novel Flow Visualization Technique Using Bioluminescent Marine Plankton—Part I: Laboratory Studies Ieee Journal of Oceanic Engineering. 20: 144-147. DOI: 10.1109/48.376679  0.042
1965 Rohr J, Pallardy G. New procedure of practical marking for radiography of the optical canal with Hartmann's incidence Journal De Radiologie, D"Electrologie, Et De Medecine Nucleaire. 46: 647-648. PMID 5858177  0.041
1986 Rohr J, Gauthier G. Pulsatile tinnitus and arteriovenous fistula of the dura mater Schweizerische Medizinische Wochenschrift. 116: 598-603. PMID 3520813  0.04
1984 Rohr J. Carotid artery stenoses: Early diagnosis Schweizerische Medizinische Wochenschrift. 114: 974-982. PMID 6474121  0.039
2006 Ibrahim F, Rohr J, Jeong WJ, Hesson J, Cerutti H. Untemplated oligoadenylation promotes degradation of RISC-cleaved transcripts Science. 314: 1893. PMID 17185594 DOI: 10.1126/Science.1135268  0.039
2015 McMahon TA, Rohr JR. Transition of chytrid fungus infection from mouthparts to hind limbs during amphibian metamorphosis. Ecohealth. 12: 188-93. PMID 25384612 DOI: 10.1007/S10393-014-0989-9  0.039
2004 Stokes MD, Deane GB, Latz MI, Rohr J. Bioluminescence imaging of wave-induced turbulence Journal of Geophysical Research C: Oceans. 109. DOI: 10.1029/2003Jc001871  0.038
1992 Gerlitz M, Hammann P, Thiericke R, Rohr J. The biogenetic origin of the carbon skeleton and the oxygen atoms of elaiophylin, a symmetric macrodiolide antibiotic Journal of Organic Chemistry. 57: 4030-4033.  0.038
2009 Latz MI, Allen J, Sarkar S, Rohr J. Effect of fully characterized unsteady flow on population growth of the dinoflagellate Lingulodinium polyedrum Limnology and Oceanography. 54: 1243-1256. DOI: 10.4319/Lo.2009.54.4.1243  0.037
2000 Chan JJ, Rohr JB. Acne vulgaris: yesterday, today and tomorrow Australasian Journal of Dermatology. 41. PMID 11105385  0.037
1992 Rohr J, Detsch R. A low sea-state study of the quieting effect of monomolecular films on the underlying ambient-noise field Journal of the Acoustical Society of America. 92: 365-383.  0.036
2014 Civitello DJ, Rohr JR. Disentangling the effects of exposure and susceptibility on transmission of the zoonotic parasite Schistosoma mansoni. The Journal of Animal Ecology. 83: 1379-86. PMID 24702134 DOI: 10.1111/1365-2656.12222  0.036
2005 Steinbeck T, Rohr J, Warnck S. Functional model for gas sensing based on quantum cascade lasers Technisches Messen. 72: 413-420. DOI: 10.1524/teme.72.6.413.65629  0.036
1985 Rohr J, Gauthier G. Spontaneous regression of a posterior fossa dural arteriovenous malformation Revue Neurologique. 141: 240-244. PMID 3890074  0.034
1994 ROHR JA. Executive Power and Republican Principles at the Founding of the Fifth Republic Governance. 7: 113-134. DOI: 10.1111/j.1468-0491.1994.tb00173.x  0.034
1987 Rohr J, Van Atra C. Mixing efficiency in stably stratified growing turbulence Journal of Geophysical Research: Oceans. 92: 5481-5488. DOI: 10.1029/JC092iC05p05481  0.034
1985 Rohr J, Gauthier G. Ultrasound examinations and detection of a post-traumatic vertebral arteriovenous fistula Revue Neurologique. 141: 464-470. PMID 3911342  0.034
1987 Rohr J, Gauthier G. Spontaneous dissecting hematoma of both internal carotid arteries with an interval of three and a half years between them Revue Neurologique. 143: 115-120. PMID 3602789  0.034
2004 Rohr JA. On Cooper's "big questions", Public Administration Review. 64: 408-409. DOI: 10.1111/j.1540-6210.2004.00387.x  0.033
2008 Rohr J. Bewertung von Markenwerten und Kundenbeziehungen im Rahmen der Kaufpreisallokation Controlling & Management. 53: 75-79. DOI: 10.1365/s12176-012-0231-y  0.033
1999 Latz MI, Rohr J. Luminescent response of the red tide dinoflagellate Lingulodinium polyedrum to laminar and turbulent flow Limnology and Oceanography. 44: 1423-1435. DOI: 10.4319/Lo.1999.44.6.1423  0.033
1998 Rohr J, Latz MI, Fallon S, Nauen JC, Hendricks E. Experimental approaches towards interpreting dolphin-stimulated bioluminescence Journal of Experimental Biology. 201: 1447-1460. PMID 9547324  0.033
1996 Anderson GW, Rohr JJ, Hoyt JW. An experimental investigation of polymer drag-reduction scale-up American Society of Mechanical Engineers, Fluids Engineering Division (Publication) Fed. 237: 19-21.  0.032
1989 Rohr J, Glass R, Castile B. Effect of monomolecular films on the underlying ocean ambient-noise field Journal of the Acoustical Society of America. 85: 1148-1157. DOI: 10.1121/1.397444  0.032
1997 Rohr J, Allen J, Losee J, Latz MI. The use of bioluminescence as a flow diagnostic Physics Letters, Section a: General, Atomic and Solid State Physics. 228: 408-416. DOI: 10.1016/S0375-9601(97)00034-0  0.032
2013 Sears BF, Rohr JR. Loss of trematode parthenitae in Planorbella trivolvis (Mollusca: Gastropoda). The Journal of Parasitology. 99: 738-9. PMID 23387507 DOI: 10.1645/12-111.1  0.031
1988 Rohr JA. Bureaucratic Morality in the United States International Political Science Review. 9: 167-178. DOI: 10.1177/019251218800900302  0.031
2002 Rehm RS, Rohr JA. Parents', nurses', and educators' perceptions of risks and benefits of school attendance by children who are medically fragile/technology-dependent. Journal of Pediatric Nursing. 17: 345-53. PMID 12395302 DOI: 10.1053/jpdn.2002.127174  0.03
2000 Brand R, Rohr JB. Toxic epidermal necrolysis in Western Australia Australasian Journal of Dermatology. 41: 31-33. PMID 10715897 DOI: 10.1046/j.1440-0960.2000.00384.x  0.03
1990 Rohr J, Losee J, Hoyt J. Stimulation of bioluminescence by turbulent pipe flow Deep Sea Research Part a, Oceanographic Research Papers. 37: 1639-1646. DOI: 10.1016/0198-0149(90)90066-5  0.03
2002 Rohr J, Hyman M, Fallon S, Latz MI. Bioluminescence flow visualization in the ocean: An initial strategy based on laboratory experiments Deep-Sea Research Part I: Oceanographic Research Papers. 49: 2009-2033. DOI: 10.1016/S0967-0637(02)00116-4  0.03
1967 Weinreich J, Rohr J. Autoimmune hemolytic anemia as a possible complication of prolonged treatment with alpha-methyl-dopa Deutsche Medizinische Wochenschrift. 92: 161-163. PMID 6016323  0.03
1965 ROHR JH, SCHEUREN JP. LYMPHANGIOSARCOMA ARISING IN A CHRONICALLY EDEMATOUS ARM FOLLOWING RADICAL MASTECTOMY The Journal of the Kansas Medical Society. 66: 98-101. PMID 14270257  0.029
2015 Ortega N, Price W, Campbell T, Rohr J. Acquired and introduced macroparasites of the invasive Cuban treefrog, Osteopilus septentrionalis International Journal For Parasitology: Parasites and Wildlife. 4: 379-384. DOI: 10.1016/j.ijppaw.2015.10.002  0.028
2002 Rohr JA. Musings on the state a reply to Mark Rutgers's "Traditional Flavors", Administration and Society. 33: 664-670. DOI: 10.1177/0095399702033006004  0.028
1962 ROHR JH. A new noscapine formulation for the relief of symptoms associated with respiratory tract disorders Current Therapeutic Research, Clinical and Experimental. 4: 21-23. PMID 14493423  0.028
2010 Rohr JR, Raffel TR. Linking global climate and temperature variability to widespread amphibian declines putatively caused by disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 8269-74. PMID 20404180 DOI: 10.1073/Pnas.0912883107  0.026
1999 Schießl UP, Rohr J. 60°C lead salt laser emission near 5-μm wavelength Infrared Physics and Technology. 40: 325-328. DOI: 10.1016/S1350-4495(99)00028-6  0.025
1983 Rohr J. Detection of extracranial carotid stenoses by spectral analysis of the Doppler signal and echotomography Revue Medicale De La Suisse Romande. 103: 281-293. PMID 6878956  0.023
2002 Rohr JA. Dicey's ghost and administrative law Administration and Society. 34: 8-31. DOI: 10.1177/0095399702034001003  0.022
1975 Rohr JB. The skin of the newborn Australasian Journal of Dermatology. 16: 118-120. PMID 1222015  0.022
2010 Rohr J, He Y. Preservice teachers and parents: Using a reading course to change perceptions and practice Educational Studies. 36: 35-45. DOI: 10.1080/03055690903148530  0.021
2000 Tait CP, Yu LL, Rohr J. Sjogren's syndrome and granulomatous panniculitis Australasian Journal of Dermatology. 41: 187-189. PMID 10954994 DOI: 10.1046/j.1440-0960.2000.00428.x  0.021
1984 Rohr J, Gauthier G. Bilateral optic nerve meningiomas associated with partial unilateral Duane's retraction syndrome Revue Neurologique. 140: 637-641. PMID 6505491  0.02
1947 ROHR JH, RHOADS PS. The indication, dosage, and mode of administration of sodium bicarbonate with sulfonamides Quarterly Bulletin. Northwestern University (Evanston, Ill.). Medical School. 21: 130-134. PMID 20239476  0.02
1967 Rohr JA. Religious toleration in st. augustine Journal of Church and State. 9: 51-70. DOI: 10.1093/jcs/9.1.51  0.019
1982 Rohr JA. The Constitution in Public Administration: A Report on Education The American Review of Public Administration. 16: 429-431. DOI: 10.1177/027507408201600412  0.018
1982 Rohr JA. Public Administration and the Constitutional Bicentennial: An Essay on Research International Journal of Public Administration. 4: 349-380. DOI: 10.1080/01900698208524437  0.017
1980 Rohr JA. Ethics for the senior executive service: Suggestions for Management Training Administration &Amp; Society. 12: 203-216. DOI: 10.1177/009539978001200205  0.017
1988 Rohr J, Gauthier G. Idiopathic acute orbital myositis Revue Neurologique. 144: 47-48. PMID 3347808  0.017
1983 Rohr J. Importance of the Doppler effect in exploration of the arteries supplying the brain Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis. 72: 681-683. PMID 6878159  0.016
1959 REBOUL H, HEITZ F, VERGOZ L, ROHR J. Arteriophlebographic plates before & after various reparative surgical interventions on arteries of extremities, iliac & aortic termination Journal De Radiologie, D'éLectrologie &Amp; Archives D'éLectricité MéDicale. 40: 391-394. PMID 13673422  0.015
1993 Rohr J. Von Leitstrukturen zu Wirkstoffen Nachrichten Aus Chemie, Technik Und Laboratorium. 41: 1359-1362. DOI: 10.1002/nadc.19930411208  0.015
1979 Rohr JB, Quirk CJ. Treatment for transient acontholytic dermatosis. Archives of Dermatology. 115: 1033-4. PMID 485173 DOI: 10.1001/archderm.1979.04010090001003  0.014
1963 ROHR JH, HASKELL AR. STUDIES IN LONG TERM DECONGESTANT THERAPY. Clinical Medicine (Northfield, Ill.). 70: 2230-4. PMID 15446123  0.014
1971 Rohr JB, Taft EH. Solitary lichen planus Australasian Journal of Dermatology. 12: 111. PMID 5118087  0.013
1974 Krahenbuhl B, Rohr J. Peripheral arteries: manual palpation and examination by the Doppler method Schweizerische Medizinische Wochenschrift. 104: 240-241. PMID 4814674  0.013
2015 Rohr JA. The constitutional responsibility of the civil service Comparative Civil Service Systems in the 21st Century, 2nd Edition. 1-14. DOI: 10.1057/9781137491459.0017  0.011
2015 Boone MD, Rohr JR. The trouble with risk assessment lies at the foundation Bioscience. 65: 227-228. DOI: 10.1093/Biosci/Biu229  0.01
2008 Rohr JA. The United States Public Service Academy: The coming debate Administration and Society. 40: 659-661. DOI: 10.1177/0095399708324895  0.01
1998 Rohr JA. Current Canadian constitutionalism and the 1865 confederation debates American Review of Canadian Studies. 28: 413-444.  0.01
1997 Frank B, Eckrich H, Rohr J. Quality nursing care: Leadership makes the difference Journal of Nursing Administration. 27: 13-14. PMID 9159608 DOI: 10.1097/00005110-199705000-00004  0.01
1997 Rohr JA. Public Administration and Comparative Constitutionalism: The Case of Canadian Federalism Public Administration Review. 57: 339-346.  0.01
1989 Rohr JB, Heenan PJ. Multiple cutaneous nodules in a patient with SLE Australasian Journal of Dermatology. 30: 55-56. PMID 2486054  0.01
1988 Rohr JB. Acne in the adolescent Australian Family Physician. 17. PMID 2971347  0.01
1982 Rohr JA. Applying the Categorical Imperative to Policy Evaluation: A Critique Administration &Amp; Society. 14: 201-205. DOI: 10.1177/009539978201400206  0.01
1979 Rohr J. The narrow spinal canal: a frequently unrecognized diagnosis (author's transl) Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis. 68: 67-69. PMID 760107  0.01
1970 Rohr J, Uthgenannt H, Weinreich J. Antithyroid antibodies and thyroid gland function disorders in chronic liver diseases Acta Hepato-Splenologica. 17: 26-36. PMID 4191125  0.01
1948 Rohr JH, Colwell AR. Comparative time action of globin insulins Archives of Internal Medicine. 82: 54-62. PMID 18110760 DOI: 10.1001/archinte.1948.00220250064003  0.01
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